00000780032022FYfalseP4Yhttp://fasb.org/us-gaap/2022#OtherAssetsCurrent http://fasb.org/us-gaap/2022#OtherAssetsNoncurrenthttp://fasb.org/us-gaap/2022#OtherAssetsCurrent http://fasb.org/us-gaap/2022#OtherAssetsNoncurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesCurrent http://fasb.org/us-gaap/2022#OtherLiabilitiesNoncurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesCurrent http://fasb.org/us-gaap/2022#OtherLiabilitiesNoncurrenthttp://fasb.org/us-gaap/2022#OtherNonoperatingIncomeExpensehttp://fasb.org/us-gaap/2022#OtherNonoperatingIncomeExpense010204045755200%101020457015350595100P5YP7YP3YP3YP5YP1YP3YP1Yhttp://fasb.org/us-gaap/2022#OtherAssetsNoncurrenthttp://fasb.org/us-gaap/2022#OtherAssetsNoncurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesCurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesCurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesNoncurrenthttp://fasb.org/us-gaap/2022#OtherLiabilitiesNoncurrenthttp://fasb.org/us-gaap/2022#OtherNonoperatingIncomeExpense00000780032022-01-012022-12-310000078003us-gaap:CommonStockMember2022-01-012022-12-310000078003pfe:NotesDue20271.000Member2022-01-012022-12-3100000780032022-07-03iso4217:USD00000780032023-02-21xbrli:shares00000780032021-01-012021-12-3100000780032020-01-012020-12-31iso4217:USDxbrli:shares00000780032022-12-3100000780032021-12-310000078003us-gaap:PreferredStockMember2019-12-310000078003us-gaap:CommonStockMember2019-12-310000078003us-gaap:AdditionalPaidInCapitalMember2019-12-310000078003us-gaap:TreasuryStockMember2019-12-310000078003us-gaap:RetainedEarningsMember2019-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2019-12-310000078003us-gaap:ParentMember2019-12-310000078003us-gaap:NoncontrollingInterestMember2019-12-3100000780032019-12-310000078003us-gaap:RetainedEarningsMember2020-01-012020-12-310000078003us-gaap:ParentMember2020-01-012020-12-310000078003us-gaap:NoncontrollingInterestMember2020-01-012020-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2020-01-012020-12-310000078003us-gaap:CommonStockMember2020-01-012020-12-310000078003us-gaap:AdditionalPaidInCapitalMember2020-01-012020-12-310000078003us-gaap:TreasuryStockMember2020-01-012020-12-310000078003us-gaap:PreferredStockMember2020-01-012020-12-310000078003us-gaap:PreferredStockMember2020-12-310000078003us-gaap:CommonStockMember2020-12-310000078003us-gaap:AdditionalPaidInCapitalMember2020-12-310000078003us-gaap:TreasuryStockMember2020-12-310000078003us-gaap:RetainedEarningsMember2020-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2020-12-310000078003us-gaap:ParentMember2020-12-310000078003us-gaap:NoncontrollingInterestMember2020-12-3100000780032020-12-310000078003us-gaap:RetainedEarningsMember2021-01-012021-12-310000078003us-gaap:ParentMember2021-01-012021-12-310000078003us-gaap:NoncontrollingInterestMember2021-01-012021-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2021-01-012021-12-310000078003us-gaap:CommonStockMember2021-01-012021-12-310000078003us-gaap:AdditionalPaidInCapitalMember2021-01-012021-12-310000078003us-gaap:TreasuryStockMember2021-01-012021-12-310000078003us-gaap:PreferredStockMember2021-12-310000078003us-gaap:CommonStockMember2021-12-310000078003us-gaap:AdditionalPaidInCapitalMember2021-12-310000078003us-gaap:TreasuryStockMember2021-12-310000078003us-gaap:RetainedEarningsMember2021-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2021-12-310000078003us-gaap:ParentMember2021-12-310000078003us-gaap:NoncontrollingInterestMember2021-12-310000078003us-gaap:RetainedEarningsMember2022-01-012022-12-310000078003us-gaap:ParentMember2022-01-012022-12-310000078003us-gaap:NoncontrollingInterestMember2022-01-012022-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2022-01-012022-12-310000078003us-gaap:CommonStockMember2022-01-012022-12-310000078003us-gaap:AdditionalPaidInCapitalMember2022-01-012022-12-310000078003us-gaap:TreasuryStockMember2022-01-012022-12-310000078003us-gaap:PreferredStockMember2022-12-310000078003us-gaap:CommonStockMember2022-12-310000078003us-gaap:AdditionalPaidInCapitalMember2022-12-310000078003us-gaap:TreasuryStockMember2022-12-310000078003us-gaap:RetainedEarningsMember2022-12-310000078003us-gaap:AccumulatedOtherComprehensiveIncomeMember2022-12-310000078003us-gaap:ParentMember2022-12-310000078003us-gaap:NoncontrollingInterestMember2022-12-31pfe:operatingSegment0000078003us-gaap:ProductConcentrationRiskMemberus-gaap:SalesRevenueProductLineMemberpfe:TopTenProductsMember2021-01-012021-12-310000078003us-gaap:ProductConcentrationRiskMemberpfe:TopSevenProductsMemberus-gaap:SalesRevenueProductLineMember2020-01-012020-12-310000078003us-gaap:ProductConcentrationRiskMemberus-gaap:SalesRevenueProductLineMemberpfe:TopNineProductsMember2022-01-012022-12-310000078003us-gaap:ProductConcentrationRiskMemberus-gaap:SalesRevenueProductLineMemberpfe:TopTenProductsMember2022-01-012022-12-31xbrli:pure0000078003us-gaap:ProductConcentrationRiskMemberus-gaap:SalesRevenueProductLineMemberpfe:TopNineProductsMember2021-01-012021-12-310000078003us-gaap:AccountsReceivableMember2022-12-310000078003us-gaap:AccountsReceivableMember2021-12-310000078003us-gaap:OtherCurrentLiabilitiesMember2022-12-310000078003us-gaap:OtherCurrentLiabilitiesMember2021-12-310000078003us-gaap:OtherNoncurrentLiabilitiesMember2022-12-310000078003us-gaap:OtherNoncurrentLiabilitiesMember2021-12-310000078003pfe:GBTMember2022-10-050000078003pfe:GBTMember2022-10-052022-10-050000078003pfe:GBTMemberpfe:RestructuringChargesAndAcquisitionRelatedCostsMember2022-10-052022-10-050000078003pfe:GBTMemberus-gaap:InProcessResearchAndDevelopmentMember2022-10-050000078003pfe:GBTMemberus-gaap:DevelopedTechnologyRightsMember2022-10-050000078003pfe:GBTMemberus-gaap:DevelopedTechnologyRightsMember2022-10-052022-10-050000078003pfe:BiohavenMember2022-10-030000078003pfe:BiohavenMember2022-10-032022-10-030000078003pfe:BiohavenLtdMember2022-12-312022-12-310000078003pfe:BiohavenMember2021-11-012021-11-300000078003us-gaap:CollaborativeArrangementMemberpfe:BiohavenLtdMember2022-10-032022-10-030000078003us-gaap:DevelopedTechnologyRightsMemberpfe:BiohavenMember2022-10-030000078003us-gaap:DevelopedTechnologyRightsMemberpfe:BiohavenMember2022-10-032022-10-030000078003pfe:BiohavenMemberus-gaap:InProcessResearchAndDevelopmentMember2022-10-030000078003pfe:ReViralAssetAcquisitionMember2022-06-092022-06-090000078003pfe:ArenaMember2022-03-110000078003pfe:ArenaMember2022-03-112022-03-110000078003pfe:ArenaMemberpfe:RestructuringChargesAndAcquisitionRelatedCostsMember2022-03-112022-03-110000078003pfe:ArenaMemberus-gaap:InProcessResearchAndDevelopmentMember2022-03-110000078003pfe:ArenaMemberus-gaap:LicensingAgreementsMember2022-03-110000078003pfe:TrilliumMember2021-11-170000078003pfe:TrilliumMember2021-11-172021-11-170000078003pfe:TrilliumMember2021-01-012021-11-160000078003pfe:ArrayMember2019-07-300000078003pfe:ArrayMember2019-07-302019-07-300000078003pfe:RestructuringChargesAndAcquisitionRelatedCostsMemberpfe:ArrayMember2019-07-302019-07-300000078003us-gaap:DevelopedTechnologyRightsMemberpfe:ArrayMember2019-07-300000078003us-gaap:DevelopedTechnologyRightsMemberpfe:ArrayMember2019-07-302019-07-300000078003pfe:ArrayMemberus-gaap:InProcessResearchAndDevelopmentMember2019-07-300000078003pfe:ArrayMemberus-gaap:LicensingAgreementsMember2019-07-300000078003pfe:ArrayMemberpfe:LicensingAgreementsTechnologyInDevelopmentMember2019-07-300000078003pfe:ArrayMemberpfe:LicensingAgreementsDevelopedTechnologyMember2019-07-300000078003pfe:ArrayMemberpfe:LicensingAgreementsDevelopedTechnologyMember2019-07-302019-07-300000078003pfe:ArrayMemberus-gaap:InProcessResearchAndDevelopmentMember2020-01-012020-12-310000078003us-gaap:DiscontinuedOperationsDisposedOfBySaleMemberpfe:MeridianMember2021-12-310000078003us-gaap:DiscontinuedOperationsDisposedOfBySaleMemberpfe:MeridianMember2021-12-312021-12-310000078003srt:MinimumMemberpfe:TransitionServiceAgreementMemberpfe:PurchaserOfMeridianMember2021-12-312021-12-310000078003pfe:TransitionServiceAgreementMembersrt:MaximumMemberpfe:PurchaserOfMeridianMember2021-12-312021-12-310000078003pfe:ManufacturingAndSupplyAgreementMemberpfe:PurchaserOfMeridianMember2021-12-312021-12-310000078003pfe:ViatrisMember2020-11-132020-11-130000078003pfe:MylanMemberpfe:ViatrisMember2020-11-132020-11-130000078003us-gaap:DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMemberpfe:ViatrisMemberpfe:UpjohnIncMember2020-11-130000078003pfe:ViatrisMember2020-11-160000078003pfe:MylanMemberpfe:ViatrisMember2020-11-160000078003pfe:UpjohnIncMember2020-06-300000078003pfe:UpjohnFinanceB.V.Member2020-06-30iso4217:EUR0000078003pfe:UpjohnIncAndUpjohnFinanceBVMember2020-06-012020-06-300000078003pfe:UpjohnIncAndUpjohnFinanceBVMemberus-gaap:SeniorNotesMember2020-06-300000078003us-gaap:LineOfCreditMemberus-gaap:CommercialPaperMember2020-06-300000078003pfe:SeniorNotesDue2021Memberus-gaap:UnsecuredDebtMember2020-06-300000078003pfe:SeniorNotesDue2023Memberus-gaap:UnsecuredDebtMember2020-06-300000078003us-gaap:DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMemberpfe:UpjohnIncMember2020-11-160000078003us-gaap:DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMemberpfe:UpjohnIncMember2020-11-162020-11-160000078003us-gaap:DiscontinuedOperationsDisposedOfByMeansOtherThanSaleSpinoffMemberpfe:UpjohnIncMember2020-01-012020-12-310000078003pfe:ManufacturingAndSupplyAgreementMembersrt:MinimumMemberpfe:ViatrisMember2020-01-012020-12-310000078003pfe:ManufacturingAndSupplyAgreementMembersrt:MaximumMemberpfe:ViatrisMember2020-01-012020-12-310000078003pfe:TransitionServiceAgreementMembersrt:MaximumMemberpfe:ViatrisMember2020-01-012020-12-310000078003pfe:ViatrisMember2022-12-310000078003pfe:ViatrisMember2021-12-310000078003pfe:ViatrisMember2021-01-012021-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2022-01-012022-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2021-01-012021-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2020-01-012020-12-310000078003pfe:EpiPenMemberus-gaap:DiscontinuedOperationsDisposedOfBySaleMemberpfe:MeridianMember2021-01-012021-12-310000078003pfe:UpjohnIncAndUpjohnFinanceBVMemberus-gaap:SegmentDiscontinuedOperationsMember2020-01-012020-12-310000078003us-gaap:SegmentDiscontinuedOperationsMemberpfe:UpjohnFinanceBVMember2020-01-012020-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2019-07-310000078003pfe:ConsumerHealthcareJVHaleonMemberpfe:GSKMember2019-07-310000078003pfe:ConsumerHealthcareJVHaleonMember2022-07-180000078003pfe:ConsumerHealthcareJVHaleonMember2022-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2021-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2022-01-012022-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2021-01-012021-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2020-01-012020-12-310000078003pfe:GSKConsumerHealthcareMember2019-12-310000078003pfe:GSKConsumerHealthcareMembersrt:MinimumMember2022-01-012022-12-310000078003pfe:GSKConsumerHealthcareMembersrt:MaximumMember2022-01-012022-12-310000078003pfe:ConsumerHealthcareJVHaleonMember2022-10-020000078003pfe:ConsumerHealthcareJVHaleonMember2021-10-030000078003pfe:ConsumerHealthcareJVHaleonMember2021-10-042022-10-020000078003pfe:ConsumerHealthcareJVHaleonMember2020-10-042021-10-030000078003pfe:ConsumerHealthcareJVHaleonMember2019-10-012020-09-270000078003pfe:GSKMemberpfe:ConsumerHealthcareJVHaleonMemberus-gaap:DisposalGroupDisposedOfBySaleNotDiscontinuedOperationsMember2022-03-310000078003us-gaap:SeniorNotesMemberpfe:ConsumerHealthcareJVHaleonMemberpfe:ConsumerHealthcareJVSeniorNotesUSDDenominatedMember2022-03-310000078003us-gaap:SeniorNotesMemberpfe:ConsumerHealthcareJVSeniorNotesEURDenominatedMemberpfe:ConsumerHealthcareJVHaleonMember2022-03-310000078003us-gaap:SeniorNotesMemberpfe:ConsumerHealthcareJVSeniorNotesGBPDenominatedMemberpfe:ConsumerHealthcareJVHaleonMember2022-03-31iso4217:GBP0000078003pfe:ConsumerHealthcareJVHaleonMember2022-03-310000078003us-gaap:LoansPayableMemberpfe:A1365ConsumerHealthcareJVLoanMember2022-07-030000078003pfe:ConsumerHealthcareJVHaleonMember2022-07-012022-07-310000078003us-gaap:LoansPayableMemberpfe:A1365ConsumerHealthcareJVLoanMember2022-07-310000078003pfe:ViivHealthcareLimitedMember2022-12-310000078003pfe:ViivHealthcareLimitedMember2016-12-310000078003pfe:ViivHealthcareLimitedMember2022-01-012022-12-310000078003pfe:ViivHealthcareLimitedMember2021-01-012021-12-310000078003pfe:ViivHealthcareLimitedMember2020-01-012020-12-310000078003pfe:ViivHealthcareLimitedMember2022-12-310000078003pfe:ViivHealthcareLimitedMember2021-12-310000078003pfe:ViivHealthcareLimitedMember2022-01-012022-12-310000078003pfe:ViivHealthcareLimitedMember2021-01-012021-12-310000078003pfe:ViivHealthcareLimitedMember2020-01-012020-12-310000078003us-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2020-04-300000078003pfe:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOffMemberus-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2020-03-302020-06-280000078003pfe:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOffMemberus-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2021-01-012022-12-310000078003us-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2020-04-302020-04-300000078003us-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2022-06-300000078003us-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2022-06-012022-06-300000078003srt:MinimumMemberus-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2022-06-012022-06-300000078003srt:MaximumMemberus-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2022-06-012022-06-300000078003us-gaap:LicensingAgreementsMemberpfe:ValnevaSEMember2022-12-312022-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:BiohavenMember2022-01-042022-01-040000078003us-gaap:CollaborativeArrangementMemberpfe:BiohavenMember2022-01-040000078003us-gaap:CollaborativeArrangementMemberpfe:ShinglesVaccineProgramMRNABasedMemberpfe:BioNTechMember2021-12-302021-12-300000078003us-gaap:CollaborativeArrangementMemberpfe:ShinglesVaccineProgramMRNABasedMemberpfe:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOffMemberpfe:BioNTechMember2021-12-302021-12-300000078003us-gaap:CollaborativeArrangementMemberpfe:ShinglesVaccineProgramMRNABasedMemberpfe:BioNTechMember2021-12-300000078003us-gaap:CollaborativeArrangementMemberpfe:CoronavirusVaccineProgramMRNABasedMemberpfe:BioNTechMember2020-04-012020-04-300000078003us-gaap:CollaborativeArrangementMemberpfe:CoronavirusVaccineProgramMRNABasedMemberpfe:BioNTechMember2020-04-300000078003us-gaap:CollaborativeArrangementMemberpfe:CoronavirusVaccineProgramMRNABasedMemberpfe:BioNTechMember2020-03-302020-06-280000078003us-gaap:CollaborativeArrangementMemberpfe:CoronavirusVaccineProgramMRNABasedMemberpfe:BioNTechMember2020-04-090000078003us-gaap:CollaborativeArrangementMemberpfe:CoronavirusVaccineProgramMRNABasedMemberpfe:BioNTechMember2020-04-092020-04-090000078003us-gaap:CollaborativeArrangementMemberpfe:BioNTechMember2020-07-310000078003us-gaap:CollaborativeArrangementMemberpfe:BioNTechMember2022-01-012022-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:BeamMember2021-12-242021-12-240000078003pfe:BeamMemberus-gaap:CollaborativeArrangementMemberpfe:BeamMember2021-12-242021-12-240000078003us-gaap:CollaborativeArrangementMemberpfe:BeamMember2021-10-042021-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:BeamMember2021-12-240000078003us-gaap:CollaborativeArrangementMemberpfe:ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOffMemberpfe:ArvinasIncMember2021-07-212021-07-210000078003us-gaap:CollaborativeArrangementMemberpfe:ArvinasIncMember2021-07-210000078003us-gaap:CollaborativeArrangementMemberpfe:ArvinasIncMember2021-07-052021-10-030000078003us-gaap:CollaborativeArrangementMemberpfe:ArvinasIncMember2021-07-212021-07-210000078003us-gaap:CollaborativeArrangementMemberpfe:ArvinasIncMember2022-12-312022-12-310000078003pfe:MyovantMemberus-gaap:CollaborativeArrangementMember2020-12-260000078003pfe:MyovantMemberus-gaap:CollaborativeArrangementMember2020-12-262020-12-260000078003pfe:MyovantMemberus-gaap:CollaborativeArrangementMember2020-12-012020-12-310000078003pfe:MyovantMemberus-gaap:CollaborativeArrangementMemberus-gaap:DevelopedTechnologyRightsMember2020-12-260000078003us-gaap:CollaborativeArrangementMemberpfe:CStoneMember2020-09-290000078003us-gaap:CollaborativeArrangementMemberpfe:CStoneMember2022-01-012022-12-310000078003us-gaap:CollaborativeArrangementMember2022-01-012022-12-310000078003us-gaap:CollaborativeArrangementMember2021-01-012021-12-310000078003us-gaap:CollaborativeArrangementMember2020-01-012020-12-310000078003pfe:EndToEndResearchAndDevelopmentOperationsImprovementsMemberpfe:FocusedCompanyPlanMember2022-12-310000078003pfe:FocusedCompanyPlanMember2022-12-310000078003pfe:BiopharmaSegmentMemberpfe:FocusedCompanyPlanMember2022-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMember2022-01-012022-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMember2021-01-012021-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMember2020-01-012020-12-310000078003us-gaap:CostOfSalesMember2022-01-012022-12-310000078003us-gaap:CostOfSalesMember2021-01-012021-12-310000078003us-gaap:CostOfSalesMember2020-01-012020-12-310000078003us-gaap:SellingGeneralAndAdministrativeExpensesMember2022-01-012022-12-310000078003us-gaap:SellingGeneralAndAdministrativeExpensesMember2021-01-012021-12-310000078003us-gaap:SellingGeneralAndAdministrativeExpensesMember2020-01-012020-12-310000078003us-gaap:ResearchAndDevelopmentExpenseMember2022-01-012022-12-310000078003us-gaap:ResearchAndDevelopmentExpenseMember2021-01-012021-12-310000078003us-gaap:ResearchAndDevelopmentExpenseMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMember2020-01-012020-12-310000078003pfe:ArenaMemberpfe:RestructuringChargesAndAcquisitionRelatedCostsMember2022-01-012022-04-030000078003pfe:GBTMemberpfe:RestructuringChargesAndAcquisitionRelatedCostsMember2022-10-032022-12-310000078003us-gaap:EmployeeSeveranceMember2020-12-310000078003pfe:AssetImpairmentsMember2020-12-310000078003us-gaap:OtherRestructuringMember2020-12-310000078003us-gaap:EmployeeSeveranceMember2021-01-012021-12-310000078003pfe:AssetImpairmentsMember2021-01-012021-12-310000078003us-gaap:OtherRestructuringMember2021-01-012021-12-310000078003us-gaap:EmployeeSeveranceMember2021-12-310000078003pfe:AssetImpairmentsMember2021-12-310000078003us-gaap:OtherRestructuringMember2021-12-310000078003us-gaap:EmployeeSeveranceMember2022-01-012022-12-310000078003pfe:AssetImpairmentsMember2022-01-012022-12-310000078003us-gaap:OtherRestructuringMember2022-01-012022-12-310000078003us-gaap:EmployeeSeveranceMember2022-12-310000078003pfe:AssetImpairmentsMember2022-12-310000078003us-gaap:OtherRestructuringMember2022-12-310000078003pfe:BioNTechAllogeneTherapeuticsIncAndArvinasMember2022-01-012022-12-310000078003pfe:BioNTechAndCerevelTherapeuticsLLCMember2021-01-012021-12-310000078003pfe:BioNTechAndSpringWorksMember2020-01-012020-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMemberus-gaap:LicensingAgreementsMember2022-01-012022-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:BioNTechMember2021-01-012021-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMemberus-gaap:LicensingAgreementsMember2021-01-012021-12-310000078003us-gaap:OtherNonoperatingIncomeExpenseMemberus-gaap:LicensingAgreementsMember2020-01-012020-12-310000078003pfe:CK1AssetsSoldToBiogenIncMemberus-gaap:DisposalGroupDisposedOfBySaleNotDiscontinuedOperationsMember2020-12-310000078003pfe:BiopharmaSegmentMemberus-gaap:InProcessResearchAndDevelopmentMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberus-gaap:DevelopedTechnologyRightsMember2022-01-012022-12-310000078003pfe:HospiraMemberpfe:GenericSterileInjectableProductMemberpfe:LicensingAgreementsAndOtherMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:ArrayMemberus-gaap:InProcessResearchAndDevelopmentMember2020-01-012020-12-310000078003pfe:AnacorMemberpfe:BiopharmaSegmentMemberus-gaap:DevelopedTechnologyRightsMemberpfe:EucrisaMember2020-01-012020-12-310000078003pfe:HospiraMemberpfe:GenericSterileInjectableProductMemberpfe:BiopharmaSegmentMemberus-gaap:DevelopedTechnologyRightsMember2020-01-012020-12-310000078003pfe:TransitionServiceAgreementMember2022-01-012022-12-310000078003pfe:ViiVMember2022-01-012022-12-310000078003pfe:TransitionServiceAgreementMember2021-01-012021-12-310000078003pfe:ViiVMember2021-01-012021-12-310000078003pfe:TransitionServiceAgreementMember2020-01-012020-12-310000078003pfe:ViiVMember2020-01-012020-12-310000078003us-gaap:InProcessResearchAndDevelopmentMember2022-12-310000078003us-gaap:InProcessResearchAndDevelopmentMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueInputsLevel2Memberus-gaap:InProcessResearchAndDevelopmentMember2022-12-310000078003us-gaap:FairValueInputsLevel3Memberus-gaap:InProcessResearchAndDevelopmentMember2022-12-310000078003us-gaap:InProcessResearchAndDevelopmentMember2022-01-012022-12-310000078003us-gaap:DevelopedTechnologyRightsMember2022-12-310000078003us-gaap:DevelopedTechnologyRightsMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:DevelopedTechnologyRightsMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueInputsLevel3Memberus-gaap:DevelopedTechnologyRightsMember2022-12-310000078003us-gaap:DevelopedTechnologyRightsMember2022-01-012022-12-310000078003pfe:LicensingAgreementsAndOtherMember2022-12-310000078003pfe:LicensingAgreementsAndOtherMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003pfe:LicensingAgreementsAndOtherMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueInputsLevel3Memberpfe:LicensingAgreementsAndOtherMember2022-12-310000078003pfe:LicensingAgreementsAndOtherMember2022-01-012022-12-310000078003us-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueInputsLevel3Member2022-12-310000078003pfe:NoncurrentDeferredTaxAssetsAndOtherNoncurrentTaxAssetsMember2022-12-310000078003pfe:NoncurrentDeferredTaxLiabilitiesMember2022-12-310000078003pfe:NoncurrentDeferredTaxAssetsAndOtherNoncurrentTaxAssetsMember2021-12-310000078003pfe:NoncurrentDeferredTaxLiabilitiesMember2021-12-310000078003pfe:OtherTaxesPayableMember2022-12-310000078003pfe:OtherTaxesPayableMember2021-12-310000078003pfe:IncomeTaxesPayableMember2022-12-310000078003pfe:CurrentTaxAssetsMember2022-12-310000078003pfe:IncomeTaxesPayableMember2021-12-310000078003pfe:CurrentTaxAssetsMember2021-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2019-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2019-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2019-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2019-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2020-01-012020-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2020-01-012020-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2020-01-012020-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2020-01-012020-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2020-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2020-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2020-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2020-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2021-01-012021-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2021-01-012021-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2021-01-012021-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2021-01-012021-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2021-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2021-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2021-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2021-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2022-01-012022-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2022-01-012022-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2022-01-012022-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2022-01-012022-12-310000078003us-gaap:AccumulatedTranslationAdjustmentMember2022-12-310000078003us-gaap:AccumulatedGainLossNetCashFlowHedgeParentMember2022-12-310000078003us-gaap:AccumulatedNetUnrealizedInvestmentGainLossMember2022-12-310000078003us-gaap:AccumulatedDefinedBenefitPlansAdjustmentNetPriorServiceCostCreditMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:MoneyMarketFundsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignGovernmentDebtSecuritiesMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignGovernmentDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Memberus-gaap:ForeignGovernmentDebtSecuritiesMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignGovernmentDebtSecuritiesMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignGovernmentDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Memberus-gaap:ForeignGovernmentDebtSecuritiesMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMember2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMember2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ShortTermInvestmentsMemberus-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:InterestRateContractMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:ForeignExchangeContractMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:ForeignGovernmentDebtSecuritiesMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:ForeignGovernmentDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:ForeignGovernmentDebtSecuritiesMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:ForeignGovernmentDebtSecuritiesMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:ForeignGovernmentDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:ForeignGovernmentDebtSecuritiesMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberus-gaap:USGovernmentAgenciesDebtSecuritiesMemberpfe:LongtermInvestmentsMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMember2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMember2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:FairValueMeasurementsRecurringMemberpfe:LongtermInvestmentsMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:EstimateOfFairValueFairValueDisclosureMemberus-gaap:FairValueInputsLevel2Member2022-12-310000078003us-gaap:EstimateOfFairValueFairValueDisclosureMemberus-gaap:FairValueInputsLevel2Member2021-12-310000078003us-gaap:ForeignGovernmentDebtSecuritiesMember2022-12-310000078003us-gaap:ForeignGovernmentDebtSecuritiesMember2021-12-310000078003us-gaap:USGovernmentAgenciesDebtSecuritiesMember2022-12-310000078003us-gaap:USGovernmentAgenciesDebtSecuritiesMember2021-12-310000078003us-gaap:CorporateDebtSecuritiesMember2022-12-310000078003us-gaap:CorporateDebtSecuritiesMember2021-12-310000078003us-gaap:BankTimeDepositsMember2022-12-310000078003us-gaap:BankTimeDepositsMember2021-12-310000078003us-gaap:RevolvingCreditFacilityMember2022-12-310000078003us-gaap:RevolvingCreditFacilityMemberpfe:CreditFacilityMaturingNovember2026Member2022-12-310000078003us-gaap:RevolvingCreditFacilityMemberpfe:CreditFacilityMaturingNovember2027Member2022-12-310000078003us-gaap:LineOfCreditMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue2023Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue2023Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue2024Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue2024Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue2025Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue2025Memberus-gaap:UnsecuredDebtMember2021-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue2026Member2022-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue2026Member2021-12-310000078003pfe:SeniorUnsecuredDebtDue2027Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue2027Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue2028Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue2028Memberus-gaap:UnsecuredDebtMember2022-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue20292033Member2021-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue20292033Member2022-12-310000078003pfe:SeniorUnsecuredDebtDue20342038Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue20342038Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue20392043Memberus-gaap:UnsecuredDebtMember2022-12-310000078003pfe:SeniorUnsecuredDebtDue20392043Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue20442048Memberus-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtDue20442048Memberus-gaap:UnsecuredDebtMember2022-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue20492053Member2022-12-310000078003us-gaap:UnsecuredDebtMemberpfe:SeniorUnsecuredDebtDue20492053Member2021-12-310000078003us-gaap:UnsecuredDebtMember2022-12-310000078003us-gaap:UnsecuredDebtMember2021-12-310000078003pfe:SeniorUnsecuredDebtOnePointSevenNinePercentDueAugust2031Memberus-gaap:SeniorNotesMember2021-08-310000078003us-gaap:SeniorNotesMember2020-05-310000078003us-gaap:SeniorNotesMember2020-03-310000078003pfe:SeniorUnsecuredDebtOnePointNineFivePercentDue2021Memberus-gaap:SeniorNotesMember2020-11-300000078003pfe:SeniorUnsecuredDebtFivePointEightZeroPercentDue2023Memberus-gaap:SeniorNotesMember2020-11-300000078003us-gaap:SeniorNotesMember2020-11-012020-11-300000078003us-gaap:UnsecuredDebtMemberpfe:SeniorNotesDue2047Member2020-03-310000078003us-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:ForeignExchangeContractMember2022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:ForeignExchangeContractMember2021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:InterestRateContractMember2022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:InterestRateContractMember2021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMember2022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMember2021-12-310000078003us-gaap:NondesignatedMemberus-gaap:ForeignExchangeContractMember2022-12-310000078003us-gaap:NondesignatedMemberus-gaap:ForeignExchangeContractMember2021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:SalesMemberus-gaap:ForeignExchangeContractMember2022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:SalesMemberus-gaap:ForeignExchangeContractMember2021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:CashFlowHedgingMemberus-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:CashFlowHedgingMemberus-gaap:ForeignExchangeContractMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:InterestRateContractMemberus-gaap:FairValueHedgingMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:InterestRateContractMemberus-gaap:FairValueHedgingMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:NetInvestmentHedgingMemberus-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:NetInvestmentHedgingMemberus-gaap:ForeignExchangeContractMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberpfe:ForeignCurrencyShortTermBorrowingsMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberpfe:ForeignCurrencyShortTermBorrowingsMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberpfe:ForeignCurrencyDebtMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberpfe:ForeignCurrencyDebtMember2021-01-012021-12-310000078003us-gaap:NondesignatedMemberus-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003us-gaap:NondesignatedMemberus-gaap:ForeignExchangeContractMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:CostOfSalesMemberus-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:CostOfSalesMemberus-gaap:ForeignExchangeContractMember2021-01-012021-12-310000078003us-gaap:DesignatedAsHedgingInstrumentMemberus-gaap:ForeignExchangeContractMember2022-01-012022-12-310000078003pfe:ForeignCurrencyShortTermBorrowingsMember2021-12-310000078003pfe:ForeignCurrencyDebtMember2022-12-310000078003pfe:ForeignCurrencyDebtMember2021-12-310000078003us-gaap:ShortTermDebtMember2022-12-310000078003us-gaap:ShortTermDebtMember2021-12-310000078003us-gaap:LongTermDebtMember2022-12-310000078003us-gaap:LongTermDebtMember2021-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:ComirnatyMemberpfe:BioNTechMember2022-12-310000078003us-gaap:CollaborativeArrangementMemberpfe:ComirnatyMemberpfe:BioNTechMember2021-12-310000078003us-gaap:LandMember2022-12-310000078003us-gaap:LandMember2021-12-310000078003us-gaap:BuildingMembersrt:MinimumMember2022-01-012022-12-310000078003us-gaap:BuildingMembersrt:MaximumMember2022-01-012022-12-310000078003us-gaap:BuildingMember2022-12-310000078003us-gaap:BuildingMember2021-12-310000078003us-gaap:MachineryAndEquipmentMembersrt:MinimumMember2022-01-012022-12-310000078003us-gaap:MachineryAndEquipmentMembersrt:MaximumMember2022-01-012022-12-310000078003us-gaap:MachineryAndEquipmentMember2022-12-310000078003us-gaap:MachineryAndEquipmentMember2021-12-310000078003us-gaap:FurnitureAndFixturesMembersrt:MinimumMember2022-01-012022-12-310000078003us-gaap:FurnitureAndFixturesMembersrt:MaximumMember2022-01-012022-12-310000078003us-gaap:FurnitureAndFixturesMember2022-12-310000078003us-gaap:FurnitureAndFixturesMember2021-12-310000078003us-gaap:ConstructionInProgressMember2022-12-310000078003us-gaap:ConstructionInProgressMember2021-12-310000078003country:US2022-12-310000078003country:US2021-12-310000078003pfe:DevelopedEuropeMember2022-12-310000078003pfe:DevelopedEuropeMember2021-12-310000078003pfe:DevelopedRestOfWorldMember2022-12-310000078003pfe:DevelopedRestOfWorldMember2021-12-310000078003pfe:EmergingMarketsMember2022-12-310000078003pfe:EmergingMarketsMember2021-12-310000078003us-gaap:DevelopedTechnologyRightsMember2021-12-310000078003us-gaap:TradeNamesMember2022-12-310000078003us-gaap:TradeNamesMember2021-12-310000078003pfe:LicensingAgreementsAndOtherMember2022-12-310000078003pfe:LicensingAgreementsAndOtherMember2021-12-310000078003us-gaap:TradeNamesMember2022-12-310000078003us-gaap:TradeNamesMember2021-12-310000078003us-gaap:InProcessResearchAndDevelopmentMember2021-12-310000078003pfe:LicensingAgreementsAndOtherMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2022-01-012022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2021-01-012021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2020-01-012020-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-01-012022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-01-012021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2020-01-012020-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-01-012022-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-01-012021-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2020-01-012020-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMember2020-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2020-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003us-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2020-12-310000078003pfe:GroupAnnuityContractMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USpfe:DefinedBenefitPlanEquitySecuritiesGlobalEquitySecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMembercountry:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMemberpfe:OtherCommingledFundsMember2021-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003pfe:DefinedBenefitPlanEquitySecuritiesEquityCommingledFundsMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:CorporateDebtSecuritiesMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:USTreasurySecuritiesMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FixedIncomeSecuritiesMember2021-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMemberus-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003srt:PartnershipInterestMemberus-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberpfe:InsuranceContractsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:OtherAggregatedInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel2Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USpfe:InsuranceContractsMemberus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2022-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMemberus-gaap:FairValueInputsLevel1Member2021-12-310000078003country:USus-gaap:FairValueInputsLevel2Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003country:USus-gaap:FairValueInputsLevel3Memberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003us-gaap:FairValueMeasuredAtNetAssetValuePerShareMembercountry:USus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2021-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2020-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2022-01-012022-12-310000078003us-gaap:ForeignPlanMemberus-gaap:FairValueInputsLevel3Memberus-gaap:PensionPlansDefinedBenefitMember2021-01-012021-12-310000078003country:USsrt:MinimumMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MaximumMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:DefinedBenefitPlanEquitySecuritiesMembercountry:USsrt:MinimumMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:DefinedBenefitPlanEquitySecuritiesMembercountry:USsrt:MaximumMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MinimumMemberus-gaap:DefinedBenefitPlanDebtSecurityMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MaximumMemberus-gaap:DefinedBenefitPlanDebtSecurityMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MinimumMemberpfe:DefinedBenefitPlanOtherInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MaximumMemberpfe:DefinedBenefitPlanOtherInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MinimumMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MaximumMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:DefinedBenefitPlanEquitySecuritiesMembersrt:MinimumMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003us-gaap:DefinedBenefitPlanEquitySecuritiesMembersrt:MaximumMemberus-gaap:ForeignPlanMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MinimumMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanDebtSecurityMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MaximumMemberus-gaap:ForeignPlanMemberus-gaap:DefinedBenefitPlanDebtSecurityMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MinimumMemberus-gaap:ForeignPlanMemberpfe:DefinedBenefitPlanOtherInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003srt:MaximumMemberus-gaap:ForeignPlanMemberpfe:DefinedBenefitPlanOtherInvestmentsMemberus-gaap:PensionPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MinimumMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MaximumMemberus-gaap:DefinedBenefitPlanCashAndCashEquivalentsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MinimumMemberpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003country:USsrt:MaximumMemberpfe:InsuranceContractsMemberus-gaap:OtherPostretirementBenefitPlansDefinedBenefitMember2022-12-310000078003pfe:December2018StockPurchasePlanMember2018-12-310000078003us-gaap:CommonStockMember2020-05-042020-05-0400000780032020-05-04pfe:employeeStockOwnershipPlan0000078003pfe:CommonESOPPlanMember2021-01-012021-12-310000078003pfe:CommonESOPPlanMember2022-01-012022-12-310000078003pfe:CommonESOPPlanMember2020-01-012020-12-310000078003pfe:A2019StockPlanMember2022-01-012022-12-310000078003pfe:A2014StockPlanMember2022-01-012022-12-310000078003pfe:A2019StockPlanMemberpfe:BreakthroughPerformanceAwardsMember2022-01-012022-12-310000078003pfe:A2019StockPlanMemberus-gaap:RestrictedStockUnitsRSUMember2022-01-012022-12-310000078003us-gaap:PerformanceSharesMemberpfe:A2019StockPlanMember2022-01-012022-12-310000078003pfe:A2019StockPlanMemberpfe:PortfolioPerformanceSharesMember2022-01-012022-12-310000078003pfe:A2019StockPlanMemberus-gaap:EmployeeStockOptionMember2022-01-012022-12-310000078003pfe:A2019StockPlanMemberpfe:TotalShareholderReturnUnitsTSRUsMember2022-01-012022-12-310000078003pfe:GBTArenaAndBiohavenAcquisitionsMember2022-12-310000078003srt:MinimumMemberpfe:TotalShareholderReturnUnitsTSRUsMember2022-01-012022-12-310000078003srt:MaximumMemberpfe:TotalShareholderReturnUnitsTSRUsMember2022-01-012022-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2022-01-012022-12-31pfe:tradingDay0000078003us-gaap:RestrictedStockUnitsRSUMember2022-01-012022-12-310000078003srt:MinimumMemberpfe:PortfolioPerformanceSharesMember2022-01-012022-12-310000078003srt:MaximumMemberpfe:PortfolioPerformanceSharesMember2022-01-012022-12-310000078003us-gaap:PerformanceSharesMember2022-01-012022-12-31pfe:measurepfe:period0000078003us-gaap:PerformanceSharesMembersrt:MinimumMember2022-01-012022-12-310000078003us-gaap:PerformanceSharesMembersrt:MaximumMember2022-01-012022-12-310000078003pfe:BreakthroughPerformanceAwardsMember2022-01-012022-12-310000078003pfe:BreakthroughPerformanceAwardsMembersrt:MinimumMember2022-01-012022-12-310000078003pfe:BreakthroughPerformanceAwardsMembersrt:MaximumMember2022-01-012022-12-310000078003srt:ManagementMember2022-01-012022-12-310000078003us-gaap:EmployeeStockOptionMember2022-01-012022-12-310000078003srt:BoardOfDirectorsChairmanMemberpfe:PerformanceTotalShareholderReturnUnitPTSRUsMember2017-01-012017-12-310000078003pfe:GroupPresidentChiefBusinessOfficerorFormerGroupPresidentPfizerInnovativeHealthMemberpfe:PerformanceTotalShareholderReturnUnitPTSRUsMember2017-01-012017-12-310000078003pfe:PerformanceTotalShareholderReturnUnitPTSRUsMember2017-01-012017-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2021-01-012021-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2020-01-012020-12-310000078003us-gaap:RestrictedStockUnitsRSUMember2021-01-012021-12-310000078003us-gaap:RestrictedStockUnitsRSUMember2020-01-012020-12-310000078003pfe:PortfolioPerformanceSharesMember2022-01-012022-12-310000078003pfe:PortfolioPerformanceSharesMember2021-01-012021-12-310000078003pfe:PortfolioPerformanceSharesMember2020-01-012020-12-310000078003us-gaap:PerformanceSharesMember2021-01-012021-12-310000078003us-gaap:PerformanceSharesMember2020-01-012020-12-310000078003us-gaap:EmployeeStockOptionMember2021-01-012021-12-310000078003us-gaap:EmployeeStockOptionMember2020-01-012020-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2022-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2021-12-310000078003pfe:TotalShareholderReturnUnitsTSRUsMember2020-12-310000078003us-gaap:RestrictedStockUnitsRSUMember2022-12-310000078003us-gaap:RestrictedStockUnitsRSUMember2021-12-310000078003us-gaap:RestrictedStockUnitsRSUMember2020-12-310000078003pfe:PortfolioPerformanceSharesMember2022-12-310000078003pfe:PortfolioPerformanceSharesMember2021-12-310000078003pfe:PortfolioPerformanceSharesMember2020-12-310000078003us-gaap:PerformanceSharesMember2022-12-310000078003us-gaap:PerformanceSharesMember2021-12-310000078003us-gaap:PerformanceSharesMember2020-12-310000078003us-gaap:EmployeeStockOptionMember2022-12-310000078003us-gaap:EmployeeStockOptionMember2021-12-310000078003us-gaap:EmployeeStockOptionMember2020-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2022-01-012022-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2021-01-012021-12-310000078003us-gaap:SegmentDiscontinuedOperationsMember2020-01-012020-12-310000078003pfe:BreakthroughPerformanceAwardsMember2021-12-310000078003pfe:BreakthroughPerformanceAwardsMember2022-12-310000078003pfe:ProfitUnitsMember2022-12-310000078003pfe:ProfitUnitsMember2022-01-012022-12-310000078003srt:MinimumMember2022-12-310000078003srt:MaximumMember2022-12-310000078003srt:MinimumMember2022-01-012022-12-310000078003srt:MaximumMember2022-01-012022-12-310000078003pfe:PfizerAndVersusSeveralGenericManufacturersMemberpfe:PatentInfringementMemberus-gaap:PendingLitigationMemberpfe:MektoviMemberpfe:Expiring2030Member2022-08-012022-08-31pfe:patent0000078003pfe:Expiring2033Memberpfe:PfizerAndVersusSeveralGenericManufacturersMemberpfe:PatentInfringementMemberus-gaap:PendingLitigationMemberpfe:MektoviMember2022-08-012022-08-310000078003pfe:PfizerAndVersusSeveralGenericManufacturersMemberpfe:PatentInfringementMemberpfe:MektoviMemberus-gaap:PendingLitigationMember2022-08-012022-08-310000078003pfe:ModernaTXUSPatentInfringementCaseMemberpfe:ComirnatyMember2022-08-012022-08-310000078003pfe:ComirnatyMemberpfe:ModernaTXEuropeanPatentInfringementCaseMember2022-09-012022-09-300000078003pfe:PfizerBioNTechAndBioNTechManufacturingGmbHVersusCureVacJudgmentOfNonInfringementMemberpfe:ComirnatyMember2022-07-012022-07-310000078003pfe:DocetaxelMemberpfe:PfizerAndHospiraAndVariousOtherManufacturersVersusMississippiAttorneyGeneralMemberus-gaap:PendingLitigationMember2018-01-012018-12-31pfe:manufacturer0000078003pfe:BiopharmaSegmentMemberus-gaap:OperatingSegmentsMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberus-gaap:OperatingSegmentsMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberus-gaap:OperatingSegmentsMember2020-01-012020-12-310000078003us-gaap:CorporateNonSegmentMember2022-01-012022-12-310000078003us-gaap:CorporateNonSegmentMember2021-01-012021-12-310000078003us-gaap:CorporateNonSegmentMember2020-01-012020-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAmortizationOfIntangibleAssetsMember2022-01-012022-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAmortizationOfIntangibleAssetsMember2021-01-012021-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAmortizationOfIntangibleAssetsMember2020-01-012020-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAcquisitionRelatedCostsMember2022-01-012022-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAcquisitionRelatedCostsMember2021-01-012021-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsAcquisitionRelatedCostsMember2020-01-012020-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsOtherMember2022-01-012022-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsOtherMember2021-01-012021-12-310000078003us-gaap:MaterialReconcilingItemsMemberpfe:ReconcilingItemsOtherMember2020-01-012020-12-310000078003srt:RevisionOfPriorPeriodReclassificationAdjustmentMemberus-gaap:CorporateNonSegmentMember2021-01-012021-12-310000078003srt:RevisionOfPriorPeriodReclassificationAdjustmentMemberpfe:BiopharmaSegmentMemberus-gaap:OperatingSegmentsMember2021-01-012021-12-310000078003srt:RevisionOfPriorPeriodReclassificationAdjustmentMemberus-gaap:CorporateNonSegmentMember2020-01-012020-12-310000078003srt:RevisionOfPriorPeriodReclassificationAdjustmentMemberpfe:BiopharmaSegmentMemberus-gaap:OperatingSegmentsMember2020-01-012020-12-310000078003pfe:PaxlovidMemberus-gaap:CorporateNonSegmentMember2022-01-012022-12-310000078003country:US2022-01-012022-12-310000078003country:US2021-01-012021-12-310000078003country:US2020-01-012020-12-310000078003pfe:DevelopedEuropeMember2022-01-012022-12-310000078003pfe:DevelopedEuropeMember2021-01-012021-12-310000078003pfe:DevelopedEuropeMember2020-01-012020-12-310000078003pfe:DevelopedRestOfWorldMember2022-01-012022-12-310000078003pfe:DevelopedRestOfWorldMember2021-01-012021-12-310000078003pfe:DevelopedRestOfWorldMember2020-01-012020-12-310000078003pfe:EmergingMarketsMember2022-01-012022-12-310000078003pfe:EmergingMarketsMember2021-01-012021-12-310000078003pfe:EmergingMarketsMember2020-01-012020-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:NonUnitedStatesMember2022-12-31pfe:country0000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:NonUnitedStatesMember2021-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:NonUnitedStatesMember2020-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:US2021-01-012021-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:US2020-01-012020-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:US2022-01-012022-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:JP2022-01-012022-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:JP2021-01-012021-12-310000078003us-gaap:GeographicConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMembercountry:JP2020-01-012020-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:McKessonInc.Member2022-01-012022-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:McKessonInc.Member2021-01-012021-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:McKessonInc.Member2020-01-012020-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:AmerisourceBergenCorporationMember2022-01-012022-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:AmerisourceBergenCorporationMember2021-01-012021-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:AmerisourceBergenCorporationMember2020-01-012020-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:CardinalHealthInc.Member2022-01-012022-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:CardinalHealthInc.Member2021-01-012021-12-310000078003us-gaap:CustomerConcentrationRiskMemberus-gaap:RevenueFromContractWithCustomerMemberpfe:CardinalHealthInc.Member2020-01-012020-12-310000078003us-gaap:AccountsReceivableMemberus-gaap:CustomerConcentrationRiskMemberpfe:ThreeLargestUSWholesaleCustomersMember2022-01-012022-12-310000078003us-gaap:AccountsReceivableMemberus-gaap:CustomerConcentrationRiskMemberpfe:ThreeLargestUSWholesaleCustomersMember2021-01-012021-12-310000078003us-gaap:AccountsReceivableMemberus-gaap:CustomerConcentrationRiskMemberpfe:ThreeLargestUSWholesaleCustomersMember2020-01-012020-12-310000078003us-gaap:CustomerConcentrationRiskMemberpfe:GovernmentAndGovernmentSponsoredMemberus-gaap:SalesRevenueNetMember2022-01-012022-12-310000078003us-gaap:CustomerConcentrationRiskMemberpfe:GovernmentAndGovernmentSponsoredMemberus-gaap:SalesRevenueNetMember2021-01-012021-12-310000078003us-gaap:AccountsReceivableMemberus-gaap:CreditConcentrationRiskMemberpfe:GovernmentAndGovernmentSponsoredMember2022-01-012022-12-310000078003us-gaap:AccountsReceivableMemberus-gaap:CreditConcentrationRiskMemberpfe:GovernmentAndGovernmentSponsoredMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:ComirnatyMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:ComirnatyMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:ComirnatyMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:PaxlovidMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:PaxlovidMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:PaxlovidMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:EliquisMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:EliquisMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:EliquisMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:PrevnarPrevenarFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:PrevnarPrevenarFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:PrevnarPrevenarFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:PremarinFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:PremarinFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:PremarinFamilyMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:BMP2Member2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:BMP2Member2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:BMP2Member2020-01-012020-12-310000078003pfe:NimenrixMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:NimenrixMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:NimenrixMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:NurtecODTVyduraMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:NurtecODTVyduraMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:NurtecODTVyduraMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:FSMEIMMUNTicoVacMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:FSMEIMMUNTicoVacMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:FSMEIMMUNTicoVacMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:ToviazMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:ToviazMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:ToviazMemberpfe:BiopharmaSegmentMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:TrumenbaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:TrumenbaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:TrumenbaMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:ChantixChampixMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:ChantixChampixMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:PrimaryCareMemberpfe:ChantixChampixMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherPrimaryCareProductsMemberpfe:PrimaryCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherPrimaryCareProductsMemberpfe:PrimaryCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherPrimaryCareProductsMemberpfe:PrimaryCareMember2020-01-012020-12-310000078003pfe:SpecialtyCareMemberpfe:BiopharmaSegmentMember2022-01-012022-12-310000078003pfe:SpecialtyCareMemberpfe:BiopharmaSegmentMember2021-01-012021-12-310000078003pfe:SpecialtyCareMemberpfe:BiopharmaSegmentMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VyndaqelMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VyndaqelMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VyndaqelMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:XeljanzMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:XeljanzMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:XeljanzMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:EnbrelMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:EnbrelMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:EnbrelMember2020-01-012020-12-310000078003pfe:SulperazonMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:SulperazonMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:SulperazonMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:InflectraRemsimaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:InflectraRemsimaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:InflectraRemsimaMember2020-01-012020-12-310000078003pfe:IgPortfolioProductsMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:IgPortfolioProductsMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:IgPortfolioProductsMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BeneFIXMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:BeneFIXMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:BeneFIXMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZaviceftaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZaviceftaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZaviceftaMember2020-01-012020-12-310000078003pfe:GenotropinMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:GenotropinMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:GenotropinMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZithromaxZmaxMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZithromaxZmaxMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:ZithromaxZmaxMember2020-01-012020-12-310000078003pfe:MedrolMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:MedrolMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:MedrolMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:FragminMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:FragminMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:FragminMember2020-01-012020-12-310000078003pfe:SomavertMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:SomavertMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:SomavertMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:ReFactoAfXynthaMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:ReFactoAfXynthaMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:ReFactoAfXynthaMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VfendMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VfendMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:VfendMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OxbrytaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OxbrytaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OxbrytaMember2020-01-012020-12-310000078003pfe:OtherAntiinfectivesMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2022-01-012022-12-310000078003pfe:OtherAntiinfectivesMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2021-01-012021-12-310000078003pfe:OtherAntiinfectivesMemberpfe:BiopharmaSegmentMemberpfe:SpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OtherSpecialtyCareMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OtherSpecialtyCareMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SpecialtyCareMemberpfe:OtherSpecialtyCareMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:IbranceMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:IbranceMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:IbranceMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:XtandiAllianceRevenuesMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:XtandiAllianceRevenuesMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:XtandiAllianceRevenuesMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:InlytaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:InlytaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:InlytaMember2020-01-012020-12-310000078003pfe:BosulifMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BosulifMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BosulifMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:ZirabevMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:ZirabevMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:ZirabevMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:XalkoriMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:XalkoriMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:XalkoriMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:RuxienceMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:RuxienceMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:RuxienceMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:RetacritMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:RetacritMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:RetacritMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:SutentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:SutentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:SutentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:LorbrenaMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:LorbrenaMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:LorbrenaMember2020-01-012020-12-310000078003pfe:BavencioAllianceRevenuesMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BavencioAllianceRevenuesMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BavencioAllianceRevenuesMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:AromasinMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:AromasinMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:AromasinMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:BesponsaMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:BesponsaMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:BesponsaMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:TrazimeraMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:TrazimeraMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:TrazimeraMemberpfe:BiopharmaSegmentMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:BraftoviMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:BraftoviMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OncologyMemberpfe:BraftoviMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:MektoviMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:MektoviMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:MektoviMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherOncologyProductsMemberpfe:OncologyMember2022-01-012022-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherOncologyProductsMemberpfe:OncologyMember2021-01-012021-12-310000078003pfe:BiopharmaSegmentMemberpfe:OtherOncologyProductsMemberpfe:OncologyMember2020-01-012020-12-310000078003pfe:PfizerCentreOneSegmentMember2022-01-012022-12-310000078003pfe:PfizerCentreOneSegmentMember2021-01-012021-12-310000078003pfe:PfizerCentreOneSegmentMember2020-01-012020-12-310000078003pfe:TotalAllianceBiopharmaceuticalsMember2022-01-012022-12-310000078003pfe:TotalAllianceBiopharmaceuticalsMember2021-01-012021-12-310000078003pfe:TotalAllianceBiopharmaceuticalsMember2020-01-012020-12-310000078003pfe:PfizerCentreOneSegmentMemberpfe:BioNTechMember2022-01-012022-12-310000078003pfe:PfizerCentreOneSegmentMemberpfe:BioNTechMember2021-01-012021-12-310000078003pfe:PfizerCentreOneSegmentMemberpfe:BioNTechMember2020-01-012020-12-310000078003pfe:GovernmentAndGovernmentSponsoredMemberpfe:ComirnatyMember2022-12-310000078003pfe:GovernmentAndGovernmentSponsoredMemberpfe:ComirnatyMember2021-12-310000078003pfe:GovernmentAndGovernmentSponsoredMemberpfe:ComirnatyMember2022-01-012022-12-31