SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 8-K
CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

Date of report (Date of earliest event reported): November 29, 2007

SCIENTIFIC INDUSTRIES, INC.
(Exact name of registrant as specified in its charter) 

Delaware                 000-6658               04-2217279
_______________         ____________    __________________
(State or other   (Commission            (IRS Employer No.)
jurisdiction of    File Number)
incorporation)

70 Orville Drive
Bohemia, New York 11716
(Address of principal executive offices)

(631) 567-4700
Registrant's telephone number, including area code

Not Applicable
(Former name or former address, if changed since last report)

ITEM 5.03 Amendment to By-laws

On November 29, 2007, the Board of Directors of the Registrant amended the Registrant's By-Laws to permit the issuance by the Registrant of uncertificated shares or book entry shares.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS

(a) and (b) not applicable. 

(c) Exhibits

Exhibit No.          Exhibit
__________   _________________________
3(ii)(a)         Article V. Section 1 of the Amended and Restated By-Laws, as

amended on November 29, 2007.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

SCIENTIFIC INDUSTRIES, INC.
(Registrant) 

Date: December 5, 2007                     By: /s/ Helena R. Santos
                                           Helena R. Santos
                                           President and Chief Executive
                                                 Officer

Exhibit 3 (ii)(a)

ARTICLE V, Section 1 As Amended

"Section 1. Certificates of Stock. Certificates of stock, numbered and with the seal of the Corporation affixed, signed by any of the Chief Executive Officer, President or Vice-President, and any of the Chief Financial Officer, the Treasurer or an Assistant Treasurer, or Secretary or an Assistant Secretary, shall be issued to each stockholder certifying the number of shares owned by such holder in the Corporation. When such certificates are signed by a transfer agent or an assistant transfer agent or by a transfer clerk acting on behalf of the Corporation and a registrar, the signatures of such officers of the Corporation may be facsimiles. Notwithstanding any other provision of this Article V, the Board of Directors may by resolution determine to issue certificateless shares, for registration in book entry accounts for shares of stock in such form as the appropriate officers of the Company may form time to time prescribe, in addition to or in place of shares of the Company represented by certificates, to the extent authorized by applicable law."