UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-CSR

CERTIFIED SHAREHOLDER REPORT OF REGISTERED
MANAGEMENT INVESTMENT COMPANIES

Investment Company Act file number 811-00816
AMERICAN CENTURY MUTUAL FUNDS, INC.
(Exact name of registrant as specified in charter)
4500 MAIN STREET, KANSAS CITY, MISSOURI 64111
(Address of principal executive offices) (Zip Code)
CHARLES A. ETHERINGTON
4500 MAIN STREET, KANSAS CITY, MISSOURI 64111
(Name and address of agent for service)
Registrant’s telephone number, including area code: 816-531-5575
Date of fiscal year end: 10-31
Date of reporting period: 10-31-2020







ITEM 1. REPORTS TO STOCKHOLDERS.







    


IMAGE81.JPG
Annual Report
October 31, 2020
Balanced Fund
Investor Class (TWBIX)
I Class (ABINX)
R5 Class (ABGNX)























Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
34
Statement of Operations
35
Statement of Changes in Net Assets
36
Notes to Financial Statements
37
Financial Highlights
45
Report of Independent Registered Public Accounting Firm
47
Management
48
Approval of Management Agreement
51
Additional Information
55


















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
 
Total Returns as of October 31, 2020
      Average Annual Returns  
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class TWBIX 7.54% 7.49% 8.32% 10/20/88
Blended Index 8.96% 8.89% 9.39%
S&P 500 Index 9.71% 11.70% 13.00%
Bloomberg Barclays U.S. Aggregate Bond Index 6.19% 4.08% 3.55%
I Class ABINX 7.75% 7.70% 8.54% 5/1/00
R5 Class ABGNX 7.75% 8.09% 4/10/17
Average annual returns since inception are presented when ten years of performance history is not available.

The blended index combines monthly returns of two widely known indices in proportion to the asset mix of the fund. The S&P 500 Index represents 60% of the index and the remaining 40% is represented by the Bloomberg Barclays U.S. Aggregate Bond Index.



























Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
CHART-77B0227030EC4C8FAFE1.JPG
Value on October 31, 2020
Investor Class — $22,251
Blended Index — $24,530
S&P 500 Index — $33,987
Bloomberg Barclays U.S. Aggregate Bond Index — $14,177
Total Annual Fund Operating Expenses
Investor Class I Class R5 Class
0.91% 0.71% 0.71%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.

















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary
 
Equity Portfolio Managers: Steven Rossi and Guan Wang

Guan Wang joined the portfolio management team in August 2020, when Claudia Musat departed.

Fixed-Income Portfolio Managers: Bob Gahagan, Brian Howell and Charles Tan

Performance Summary

Balanced returned 7.54%* for the 12 months ended October 31, 2020. By comparison, the fund’s benchmark (a blended index consisting of 60% S&P 500 Index and 40% Bloomberg Barclays U.S. Aggregate Bond Index) returned 8.96%.

Balanced seeks long-term capital growth and current income by investing approximately 60% of its assets in equity securities and the remainder in bonds and other fixed-income securities. The purpose of the broad bond market exposure is to reduce the volatility of the equity portfolio, providing a more attractive overall risk/return profile for investors. The total fund’s drivers of both absolute and relative returns, however, are typically a function of the equity allocation. Therefore, the performance attribution discussion focuses primarily on the equity segment.

Consumer Discretionary and Information Technology Largest Equity Detractors

The largest detractors from relative performance were the consumer discretionary and information technology sectors. Within consumer discretionary, stock selection within the textiles, apparel and luxury goods industry provided a headwind. An overweight to Ralph Lauren weighed on sector results, as did reduced exposure to NIKE. We have since exited both of these positions. Positioning among specialty retail companies also hurt relative returns. Elsewhere in the sector, an underweight position in internet and direct marketing retail company Amazon was a top detractor from the portfolio’s relative performance. Due to the pandemic, a major shift occurred in consumer behavior. People stopped visiting brick-and-mortar stores and turned to online shopping. Companies with a strong online presence tended to outperform. Amazon was a leading contributor to index returns for the period because of this shift. Our exposure to Amazon was less than the benchmark, which hurt relative results.

Performance within the semiconductors and semiconductor equipment industry hampered relative results within the information technology sector. During the lockdown, chips and processors used in computer and other electronics products were in high demand, lifting the stock price of many companies within the industry. An underweight position in chip and electronic component maker NVIDIA was among the top detractors from performance. Security selection within the technology hardware,storage and peripherals and IT services industries also weighed on results.

Elsewhere, overweight exposure to media company Discovery and reduced exposure to software company Microsoft were also among the leading detractors from relative returns. Microsoft benefited during the period from increased demand for its Teams platform due to the work-from-home trend that emerged due to the pandemic. We have since exited our position in Discovery.







*All fund returns referenced in this commentary are for Investor Class shares. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.


5



Energy and Real Estate Led Equity Gains

Reduced exposure to the energy sector was a main contributor to performance compared with the benchmark for the year. The sector underperformed the broader market as slower economic growth and steps to slow the spread of the virus weighed heavily on energy demand. In addition, a pricing disagreement between Russia and Saudi Arabia worked to drive down prices even further. As a result, underweight exposure to the oil, gas and consumable fuels industry was a primary contributor to relative performance within the sector, led by reduced exposure to Exxon Mobil.

An underweight to the real estate sector also benefited relative performance. As lockdowns progressed, tenants in retail spaces began to have problems making their lease payments. Lessened exposure to equity real estate investment trusts helped to boost the portfolio’s relative performance. Underweight exposure to Simon Property Group, which owns malls, helped relative returns, as did avoidance of several other index positions. We have since exited our position in Simon Property Group.

Other top contributors to relative performance for the 12-month period included a lack of exposure to aircraft company Boeing. The company’s stock price was volatile over the period. First, continued issues stemming from the grounding of its 737 MAX aircraft depressed the price early in the period. Next, the company’s order book was hurt by the pandemic as people discontinued business travel and airlines canceled orders for new planes. The company was also confronted with continued scrutiny of its governance practices. Elsewhere, overweights to software companies Adobe and Cadence Design Systems were also among the leading performers. The companies benefited from increased demand for their products and services during the lockdown.

Bond Performance Positive

Bond market performance was strong during the year. In late 2019, the long end of the yield curve steepened, as investors felt optimistic toward economic prospects for 2020. The U.S. Federal Reserve’s (Fed) commitment to continued accommodative monetary policies helped fuel a risk-on environment, where spread products outperformed like-duration Treasuries through the end of the calendar year.

However, a shift occurred early in 2020, as the coronavirus spread across the globe. As equity and credit markets entered free-fall in March, a flight to quality ensued. The Fed, as well as other global central banks and governments, enacted historic monetary and fiscal assistance and quantitative easing programs. These efforts helped to provide liquidity within credit markets and ease investor anxiety brought on by widespread lockdowns and their dampening effects on economic activity. As part of these measures, the Fed cut the target overnight lending rate to near zero. This led to falling interest rates across much of the Treasury curve, boosting returns for Treasuries. In addition, the Fed’s purchase of corporate credit worked to support risk asset prices. Generally, investment-grade corporate debt outperformed like-duration Treasuries over the period. High-yield debt lagged the broader market, due in part to the high concentration of energy issuers within the universe. Energy companies lagged the broader market for much of the year.

Outlook

The U.S. continues to face challenges relating to the coronavirus pandemic. While hope for a vaccine and extensive central bank intervention have helped fuel a recovery in risk assets, uncertainty remains regarding the country’s economic recovery. As a result, we think it’s only prudent to expect some volatility ahead. Of course, volatility in and of itself is not a bad thing—downside volatility, for example, can provide buying opportunities. We will continue to monitor the situation and invest appropriately. We believe that the continued economic and market uncertainty highlights the benefits of a balanced approach involving exposure to both stocks and bonds, which is intended to reduce overall price fluctuations and improve risk-adjusted performance.


6



Fund Characteristics
OCTOBER 31, 2020
Key Fixed-Income Portfolio Statistics
Weighted Average Life to Maturity 8.1 years
Average Duration (effective) 6.0 years
Top Ten Common Stocks % of net assets
Apple, Inc. 3.7%
Microsoft Corp. 3.5%
Amazon.com, Inc. 3.1%
Alphabet, Inc., Class A 2.0%
Facebook, Inc., Class A 2.0%
Adobe, Inc. 1.1%
Home Depot, Inc. (The) 1.0%
Broadcom, Inc. 0.9%
Merck & Co., Inc. 0.9%
NVIDIA Corp. 0.9%
Top Five Common Stocks Industries % of net assets
Software 7.5%
Semiconductors and Semiconductor Equipment 4.9%
Interactive Media and Services 4.4%
Internet and Direct Marketing Retail 3.8%
Technology Hardware, Storage and Peripherals 3.7%
Types of Investments in Portfolio % of net assets
Common Stocks 59.1%
U.S. Treasury Securities 13.7%
Corporate Bonds 11.3%
U.S. Government Agency Mortgage-Backed Securities 10.1%
Collateralized Mortgage Obligations 2.8%
Collateralized Loan Obligations 1.8%
Asset-Backed Securities 1.4%
Municipal Securities 0.7%
U.S. Government Agency Securities 0.5%
Sovereign Governments and Agencies 0.3%
Preferred Stocks 0.1%
Temporary Cash Investments 1.2%
Other Assets and Liabilities (3.0)%

7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

8




Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period
(1)
5/1/20 - 10/31/20
 
Annualized
Expense Ratio
(1)
Actual
Investor Class $1,000 $1,078.60 $4.70 0.90%
I Class $1,000 $1,079.10 $3.66 0.70%
R5 Class $1,000 $1,079.70 $3.66 0.70%
Hypothetical
Investor Class $1,000 $1,020.61 $4.57 0.90%
I Class $1,000 $1,021.62 $3.56 0.70%
R5 Class $1,000 $1,021.62 $3.56 0.70%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.

9



Schedule of Investments

OCTOBER 31, 2020
Shares/
Principal Amount
Value
COMMON STOCKS — 59.1%
Aerospace and Defense — 0.8%
General Dynamics Corp. 9,737  $ 1,278,760 
Huntington Ingalls Industries, Inc. 4,572  674,279 
L3Harris Technologies, Inc. 15,350  2,473,038 
Lockheed Martin Corp. 7,217  2,526,888 
Textron, Inc. 23,752  850,322 
7,803,287 
Air Freight and Logistics — 0.1%
United Parcel Service, Inc., Class B 8,655  1,359,787 
Auto Components — 0.2%
BorgWarner, Inc. 42,064  1,471,399 
Banks — 1.0%
Bank of America Corp. 232,057  5,499,751 
Citigroup, Inc. 14,036  581,371 
East West Bancorp, Inc. 18,035  657,917 
JPMorgan Chase & Co. 23,736  2,327,077 
9,066,116 
Beverages — 0.1%
Coca-Cola Co. (The) 12,178  585,275 
Biotechnology — 1.5%
AbbVie, Inc. 45,187  3,845,414 
Alexion Pharmaceuticals, Inc.(1)
9,886  1,138,274 
Amgen, Inc. 3,866  838,690 
Biogen, Inc.(1)
11,791  2,972,157 
Exelixis, Inc.(1)
33,635  688,845 
Incyte Corp.(1)
22,616  1,959,450 
Regeneron Pharmaceuticals, Inc.(1)
3,132  1,702,430 
Vertex Pharmaceuticals, Inc.(1)
6,909  1,439,559 
14,584,819 
Building Products — 1.5%
Allegion plc 23,509  2,315,636 
Fortune Brands Home & Security, Inc. 68,934  5,574,693 
Masco Corp. 114,442  6,134,091 
14,024,420 
Capital Markets — 1.1%
Ameriprise Financial, Inc. 10,756  1,729,888 
Cboe Global Markets, Inc. 15  1,219 
FactSet Research Systems, Inc. 7,232  2,216,608 
Franklin Resources, Inc. 27,882  522,788 
LPL Financial Holdings, Inc. 24,833  1,984,902 
Moody's Corp. 8,606  2,262,517 
State Street Corp. 25,039  1,474,797 
10,192,719 
Chemicals — 0.3%
Eastman Chemical Co. 11,724  947,768 
10



Shares/
Principal Amount
Value
LyondellBasell Industries NV, Class A 30,029  $ 2,055,485 
3,003,253 
Communications Equipment — 0.6%
Cisco Systems, Inc. 34,124  1,225,052 
Lumentum Holdings, Inc.(1)
7,171  592,970 
Motorola Solutions, Inc. 23,503  3,714,884 
5,532,906 
Construction and Engineering — 0.3%
Quanta Services, Inc. 45,499  2,840,503 
Consumer Finance — 0.1%
Synchrony Financial 50,230  1,256,755 
Containers and Packaging — 0.7%
International Paper Co. 57,335  2,508,406 
Packaging Corp. of America 20,689  2,368,684 
WestRock Co. 38,688  1,452,734 
6,329,824 
Distributors — 0.1%
LKQ Corp.(1)
26,083  834,395 
Diversified Financial Services — 0.7%
Berkshire Hathaway, Inc., Class B(1)
33,880  6,840,372 
Diversified Telecommunication Services — 0.9%
AT&T, Inc. 86,134  2,327,341 
CenturyLink, Inc. 111,989  965,345 
Verizon Communications, Inc. 85,409  4,867,459 
8,160,145 
Electric Utilities — 0.8%
Duke Energy Corp. 20,273  1,867,346 
NextEra Energy, Inc. 7,016  513,641 
NRG Energy, Inc. 57,537  1,819,320 
PPL Corp. 94,564  2,600,510 
Southern Co. (The) 8,395  482,293 
7,283,110 
Electrical Equipment — 0.6%
Emerson Electric Co. 39,492  2,558,687 
Rockwell Automation, Inc. 12,466  2,955,938 
5,514,625 
Electronic Equipment, Instruments and Components — 0.5%
Jabil, Inc. 76,588  2,538,127 
SYNNEX Corp. 5,788  761,932 
Zebra Technologies Corp., Class A(1)
5,472  1,552,078 
4,852,137 
Entertainment — 1.6%
Activision Blizzard, Inc. 32,191  2,437,824 
Electronic Arts, Inc.(1)
43,892  5,259,578 
Netflix, Inc.(1)
2,358  1,121,795 
Take-Two Interactive Software, Inc.(1)
23,055  3,571,681 
Zynga, Inc., Class A(1)
303,646  2,729,778 
15,120,656 
Equity Real Estate Investment Trusts (REITs) — 0.2%
Iron Mountain, Inc. 23,413  610,143 
11



Shares/
Principal Amount
Value
Public Storage 3,921  $ 898,183 
1,508,326 
Food and Staples Retailing — 0.4%
BJ's Wholesale Club Holdings, Inc.(1)
55,396  2,121,113 
Kroger Co. (The) 20,104  647,550 
Walmart, Inc. 8,788  1,219,335 
3,987,998 
Food Products — 1.7%
Campbell Soup Co. 19,846  926,213 
General Mills, Inc. 55,145  3,260,172 
Hershey Co. (The) 38,594  5,305,131 
Hormel Foods Corp. 46,387  2,258,583 
J.M. Smucker Co. (The) 9,193  1,031,455 
Kellogg Co. 35,895  2,257,436 
Kraft Heinz Co. (The) 18,998  581,149 
15,620,139 
Health Care Equipment and Supplies — 1.6%
Abbott Laboratories 39,919  4,195,886 
ABIOMED, Inc.(1)
5,341  1,345,291 
Baxter International, Inc. 32,230  2,500,081 
Danaher Corp. 6,834  1,568,677 
Medtronic plc 13,360  1,343,615 
Novocure Ltd.(1)
26,286  3,209,521 
Zimmer Biomet Holdings, Inc. 6,332  836,457 
14,999,528 
Health Care Providers and Services — 2.1%
Anthem, Inc. 10,940  2,984,432 
Cardinal Health, Inc. 10,234  468,615 
CVS Health Corp. 26,025  1,459,742 
HCA Healthcare, Inc. 25,748  3,191,207 
Henry Schein, Inc.(1)
8,380  532,800 
Humana, Inc. 12,307  4,913,939 
McKesson Corp. 16,744  2,469,573 
UnitedHealth Group, Inc. 13,112  4,000,996 
20,021,304 
Health Care Technology — 0.6%
Cerner Corp. 86,245  6,044,912 
Household Durables — 0.1%
PulteGroup, Inc. 29,446  1,200,219 
Household Products — 1.5%
Colgate-Palmolive Co. 46,319  3,654,106 
Kimberly-Clark Corp. 47,353  6,278,534 
Procter & Gamble Co. (The) 33,159  4,546,099 
14,478,739 
Industrial Conglomerates — 0.6%
3M Co. 30,728  4,915,251 
Honeywell International, Inc. 6,798  1,121,330 
6,036,581 
Insurance — 1.1%
Aon plc, Class A 3,910  719,479 
Brown & Brown, Inc. 45,578  1,983,099 
12



Shares/
Principal Amount
Value
Marsh & McLennan Cos., Inc. 24,410  $ 2,525,458 
MetLife, Inc. 88,305  3,342,344 
Principal Financial Group, Inc. 39,276  1,540,405 
10,110,785 
Interactive Media and Services — 4.4%
Alphabet, Inc., Class A(1)
11,731  18,958,587 
Facebook, Inc., Class A(1)
71,484  18,808,155 
Pinterest, Inc., Class A(1)
67,814  3,997,635 
41,764,377 
Internet and Direct Marketing Retail — 3.8%
Amazon.com, Inc.(1)
9,503  28,852,534 
eBay, Inc. 102,621  4,887,838 
Wayfair, Inc., Class A(1)
7,566  1,876,595 
35,616,967 
IT Services — 1.5%
Akamai Technologies, Inc.(1)
12,043  1,145,530 
Cognizant Technology Solutions Corp., Class A 20,104  1,435,828 
International Business Machines Corp. 37,007  4,132,201 
Mastercard, Inc., Class A 6,537  1,886,840 
PayPal Holdings, Inc.(1)
4,256  792,169 
Visa, Inc., Class A 16,914  3,073,443 
Western Union Co. (The) 92,188  1,792,135 
14,258,146 
Life Sciences Tools and Services — 0.4%
Agilent Technologies, Inc. 30,643  3,128,344 
Illumina, Inc.(1)
2,643  773,606 
3,901,950 
Machinery — 0.9%
AGCO Corp. 33,480  2,578,965 
Cummins, Inc. 13,915  3,059,769 
Snap-on, Inc. 16,442  2,590,108 
8,228,842 
Media — 0.1%
Interpublic Group of Cos., Inc. (The) 34,369  621,735 
Metals and Mining — 0.4%
Reliance Steel & Aluminum Co. 19,309  2,104,488 
Steel Dynamics, Inc. 42,890  1,350,177 
3,454,665 
Multi-Utilities — 0.6%
CenterPoint Energy, Inc. 113,760  2,403,749 
Dominion Energy, Inc. 28,788  2,312,828 
Sempra Energy 8,273  1,037,103 
5,753,680 
Multiline Retail — 0.9%
Dollar Tree, Inc.(1)
7,348  663,671 
Target Corp. 52,668  8,017,123 
8,680,794 
Oil, Gas and Consumable Fuels — 0.6%
Chevron Corp. 11,336  787,852 
Exxon Mobil Corp. 35,642  1,162,642 
Kinder Morgan, Inc. 58,603  697,376 
13



Shares/
Principal Amount
Value
Williams Cos., Inc. (The) 138,792  $ 2,663,418 
5,311,288 
Personal Products — 0.6%
Estee Lauder Cos., Inc. (The), Class A 13,102  2,877,985 
Herbalife Nutrition Ltd.(1)
54,240  2,448,394 
5,326,379 
Pharmaceuticals — 2.3%
Bristol-Myers Squibb Co. 112,274  6,562,415 
Jazz Pharmaceuticals plc(1)
5,325  767,333 
Johnson & Johnson 15,434  2,116,156 
Merck & Co., Inc. 111,177  8,361,622 
Mylan NV(1)
139,717  2,031,485 
Pfizer, Inc. 46,407  1,646,520 
21,485,531 
Professional Services — 0.1%
Robert Half International, Inc. 15,465  783,921 
Road and Rail — 0.4%
Kansas City Southern 13,397  2,359,747 
Union Pacific Corp. 7,399  1,311,029 
3,670,776 
Semiconductors and Semiconductor Equipment — 4.9%
Applied Materials, Inc. 72,667  4,304,066 
Broadcom, Inc. 24,860  8,691,802 
Intel Corp. 22,377  990,853 
KLA Corp. 24,456  4,822,234 
Lam Research Corp. 9,598  3,283,284 
NVIDIA Corp. 16,194  8,119,024 
NXP Semiconductors NV 12,247  1,654,815 
Qorvo, Inc.(1)
7,388  940,936 
QUALCOMM, Inc. 50,873  6,275,693 
Skyworks Solutions, Inc. 15,969  2,256,260 
Texas Instruments, Inc. 36,071  5,215,506 
46,554,473 
Software — 7.5%
Adobe, Inc.(1)
22,767  10,179,126 
Autodesk, Inc.(1)
20,413  4,808,078 
Cadence Design Systems, Inc.(1)
20,886  2,284,302 
Dropbox, Inc., Class A(1)
90,925  1,660,290 
Fortinet, Inc.(1)
7,684  848,083 
Microsoft Corp. 165,385  33,485,501 
Oracle Corp., (New York) 80,142  4,496,767 
Palo Alto Networks, Inc.(1)
12,100  2,676,399 
Proofpoint, Inc.(1)
1,550  148,397 
salesforce.com, Inc.(1)
16,658  3,869,154 
ServiceNow, Inc.(1)
11,644  5,793,705 
VMware, Inc., Class A(1)
5,601  721,017 
70,970,819 
Specialty Retail — 2.3%
AutoZone, Inc.(1)
617  696,581 
Best Buy Co., Inc. 31,953  3,564,357 
Dick's Sporting Goods, Inc. 29,570  1,675,140 
14



Shares/
Principal Amount
Value
Home Depot, Inc. (The) 34,394  $ 9,173,224 
Lowe's Cos., Inc. 38,724  6,122,264 
Ulta Beauty, Inc.(1)
4,076  842,795 
22,074,361 
Technology Hardware, Storage and Peripherals — 3.7%
Apple, Inc. 324,953  35,374,384 
Textiles, Apparel and Luxury Goods — 0.1%
Hanesbrands, Inc. 69,555  1,117,749 
Trading Companies and Distributors — 0.2%
W.W. Grainger, Inc. 6,075  2,126,371 
TOTAL COMMON STOCKS
(Cost $424,094,611)
557,742,242 
U.S. TREASURY SECURITIES — 13.7%
U.S. Treasury Bonds, 5.00%, 5/15/37 $ 200,000  315,453 
U.S. Treasury Bonds, 3.50%, 2/15/39 150,000  204,598 
U.S. Treasury Bonds, 4.625%, 2/15/40 1,300,000  2,034,145 
U.S. Treasury Bonds, 4.375%, 5/15/41 1,400,000  2,152,172 
U.S. Treasury Bonds, 3.125%, 11/15/41 1,000,000  1,309,609 
U.S. Treasury Bonds, 3.00%, 5/15/42 3,300,000  4,249,395 
U.S. Treasury Bonds, 2.75%, 11/15/42 2,000,000  2,478,516 
U.S. Treasury Bonds, 2.875%, 5/15/43 1,300,000  1,644,855 
U.S. Treasury Bonds, 3.625%, 2/15/44 300,000  425,063 
U.S. Treasury Bonds, 3.125%, 8/15/44 500,000  659,336 
U.S. Treasury Bonds, 3.00%, 11/15/44 600,000  776,203 
U.S. Treasury Bonds, 2.50%, 2/15/45(2)
5,000,000  5,951,562 
U.S. Treasury Bonds, 3.00%, 5/15/45 600,000  777,258 
U.S. Treasury Bonds, 3.00%, 11/15/45 200,000  259,813 
U.S. Treasury Bonds, 3.375%, 11/15/48 1,900,000  2,664,824 
U.S. Treasury Bonds, 2.25%, 8/15/49 1,200,000  1,369,359 
U.S. Treasury Bonds, 2.375%, 11/15/49 1,900,000  2,225,523 
U.S. Treasury Bonds, 2.00%, 2/15/50 1,900,000  2,057,344 
U.S. Treasury Bonds, 1.25%, 5/15/50 500,000  451,563 
U.S. Treasury Bonds, 1.375%, 8/15/50 200,000  186,469 
U.S. Treasury Inflation Indexed Notes, 0.25%, 7/15/29 2,235,574  2,473,353 
U.S. Treasury Inflation Indexed Notes, 0.125%, 7/15/30 3,548,300  3,894,706 
U.S. Treasury Notes, 1.875%, 1/31/22(2)
500,000  510,859 
U.S. Treasury Notes, 0.375%, 3/31/22 5,500,000  5,518,906 
U.S. Treasury Notes, 1.875%, 3/31/22 900,000  922,078 
U.S. Treasury Notes, 0.125%, 4/30/22 5,000,000  4,999,609 
U.S. Treasury Notes, 1.875%, 4/30/22 1,800,000  1,846,688 
U.S. Treasury Notes, 0.125%, 5/31/22 300,000  299,930 
U.S. Treasury Notes, 1.75%, 6/15/22 3,000,000  3,077,812 
U.S. Treasury Notes, 1.625%, 11/15/22 3,000,000  3,089,707 
U.S. Treasury Notes, 2.00%, 11/30/22 800,000  830,625 
U.S. Treasury Notes, 0.50%, 3/15/23 18,600,000  18,744,586 
U.S. Treasury Notes, 0.25%, 4/15/23 400,000  400,766 
U.S. Treasury Notes, 0.25%, 6/15/23 500,000  500,898 
U.S. Treasury Notes, 2.875%, 11/30/23 6,600,000  7,140,891 
U.S. Treasury Notes, 2.375%, 2/29/24 1,500,000  1,607,021 
U.S. Treasury Notes, 1.125%, 2/28/25 12,200,000  12,625,094 
U.S. Treasury Notes, 0.50%, 3/31/25 1,200,000  1,209,047 
U.S. Treasury Notes, 0.25%, 5/31/25 2,000,000  1,991,797 
15



Shares/
Principal Amount
Value
U.S. Treasury Notes, 0.25%, 8/31/25 $ 6,300,000  $ 6,264,562 
U.S. Treasury Notes, 2.625%, 12/31/25 2,200,000  2,448,875 
U.S. Treasury Notes, 1.375%, 8/31/26 1,500,000  1,574,590 
U.S. Treasury Notes, 1.625%, 10/31/26 100,000  106,480 
U.S. Treasury Notes, 1.75%, 12/31/26 700,000  751,133 
U.S. Treasury Notes, 1.50%, 1/31/27 2,000,000  2,116,016 
U.S. Treasury Notes, 1.125%, 2/28/27 1,200,000  1,241,508 
U.S. Treasury Notes, 0.625%, 3/31/27 10,000,000  10,026,367 
U.S. Treasury Notes, 0.50%, 6/30/27 500,000  496,367 
U.S. Treasury Notes, 0.50%, 8/31/27 600,000  594,750 
TOTAL U.S. TREASURY SECURITIES
(Cost $122,173,126)
129,498,081 
CORPORATE BONDS — 11.3%
Aerospace and Defense — 0.1%
Boeing Co. (The), 5.15%, 5/1/30 150,000  166,271 
Boeing Co. (The), 5.81%, 5/1/50 430,000  506,857 
Lockheed Martin Corp., 3.80%, 3/1/45 80,000  95,918 
Raytheon Technologies Corp., 4.125%, 11/16/28 500,000  586,122 
1,355,168 
Airlines — 0.1%
Delta Air Lines, Inc. / SkyMiles IP Ltd., 4.50%, 10/20/25(3)
590,000  599,280 
Southwest Airlines Co., 5.125%, 6/15/27 508,000  565,567 
1,164,847 
Auto Components
BorgWarner, Inc., 2.65%, 7/1/27 210,000  220,495 
Automobiles — 0.3%
Ford Motor Credit Co. LLC, 5.875%, 8/2/21 440,000  449,878 
Ford Motor Credit Co. LLC, 2.98%, 8/3/22 400,000  397,916 
Ford Motor Credit Co. LLC, 3.35%, 11/1/22 310,000  309,259 
General Motors Co., 5.15%, 4/1/38 260,000  288,830 
General Motors Financial Co., Inc., 2.75%, 6/20/25 430,000  444,286 
General Motors Financial Co., Inc., 2.70%, 8/20/27 650,000  656,388 
2,546,557 
Banks — 1.5%
Banco Santander SA, 3.50%, 4/11/22 600,000  623,947 
Bank of America Corp., MTN, VRN, 1.32%, 6/19/26 895,000  900,431 
Bank of America Corp., MTN, VRN, 2.50%, 2/13/31 930,000  964,914 
Bank of America Corp., MTN, VRN, 2.68%, 6/19/41 600,000  607,694 
Bank of America Corp., MTN, VRN, 2.83%, 10/24/51 155,000  153,705 
Bank of America Corp., VRN, 3.00%, 12/20/23 911,000  955,962 
Barclays plc, VRN, 2.65%, 6/24/31 300,000  301,213 
BNP Paribas SA, VRN, 2.59%, 8/12/35(3)
490,000  472,673 
BPCE SA, 5.15%, 7/21/24(3)
200,000  224,571 
BPCE SA, VRN, 1.65%, 10/6/26(3)
300,000  302,257 
Citigroup, Inc., 4.05%, 7/30/22 70,000  74,212 
Citigroup, Inc., 4.65%, 7/23/48 140,000  181,533 
Citigroup, Inc., VRN, 3.11%, 4/8/26 277,000  299,444 
Citigroup, Inc., VRN, 3.52%, 10/27/28 390,000  433,046 
Citigroup, Inc., VRN, 2.57%, 6/3/31 390,000  406,343 
Cooperatieve Rabobank UA, 3.95%, 11/9/22 450,000  479,940 
DNB Bank ASA, VRN, 1.13%, 9/16/26(3)
380,000  379,762 
Fifth Third BanCorp., 4.30%, 1/16/24 110,000  121,058 
16



Shares/
Principal Amount
Value
FNB Corp., 2.20%, 2/24/23 $ 460,000  $ 465,119 
HSBC Holdings plc, VRN, 2.01%, 9/22/28 240,000  238,732 
JPMorgan Chase & Co., VRN, 4.02%, 12/5/24 220,000  242,237 
JPMorgan Chase & Co., VRN, 2.18%, 6/1/28 670,000  698,852 
JPMorgan Chase & Co., VRN, 2.52%, 4/22/31 905,000  954,909 
JPMorgan Chase & Co., VRN, 3.11%, 4/22/51 170,000  179,390 
Lloyds Banking Group plc, VRN, 2.44%, 2/5/26 540,000  563,372 
Natwest Group plc, VRN, 2.36%, 5/22/24 110,000  113,706 
Santander UK Group Holdings plc, VRN, 1.53%, 8/21/26 405,000  402,854 
Societe Generale SA, VRN, 3.65%, 7/8/35(3)
90,000  90,613 
Wells Fargo & Co., 4.125%, 8/15/23 200,000  218,452 
Wells Fargo & Co., 3.00%, 10/23/26 695,000  759,135 
Wells Fargo & Co., MTN, VRN, 2.39%, 6/2/28 525,000  545,186 
Wells Fargo & Co., VRN, 2.19%, 4/30/26 180,000  187,332 
Wells Fargo & Co., VRN, 3.07%, 4/30/41 310,000  321,870 
13,864,464 
Beverages — 0.2%
Anheuser-Busch Cos. LLC / Anheuser-Busch InBev Worldwide, Inc., 4.90%, 2/1/46 500,000  613,743 
Anheuser-Busch InBev Worldwide, Inc., 4.75%, 1/23/29 630,000  762,959 
PepsiCo, Inc., 1.625%, 5/1/30 110,000  112,130 
1,488,832 
Biotechnology — 0.4%
AbbVie, Inc., 3.25%, 10/1/22(3)
400,000  418,091 
AbbVie, Inc., 3.85%, 6/15/24(3)
440,000  482,523 
AbbVie, Inc., 3.60%, 5/14/25 120,000  133,075 
AbbVie, Inc., 3.20%, 11/21/29(3)
440,000  486,031 
AbbVie, Inc., 4.55%, 3/15/35(3)
110,000  132,274 
AbbVie, Inc., 4.40%, 11/6/42 240,000  283,434 
Gilead Sciences, Inc., 3.65%, 3/1/26 840,000  947,992 
Gilead Sciences, Inc., 1.65%, 10/1/30 420,000  414,781 
3,298,201 
Building Products
Lennox International, Inc., 1.70%, 8/1/27 140,000  139,945 
Capital Markets — 0.8%
Ares Capital Corp., 3.25%, 7/15/25 653,000  655,783 
Ares Finance Co. II LLC, 3.25%, 6/15/30(3)
305,000  316,739 
Credit Suisse Group AG, VRN, 2.59%, 9/11/25(3)
280,000  293,726 
Credit Suisse Group AG, VRN, 2.19%, 6/5/26(3)
780,000  805,909 
Goldman Sachs Group, Inc. (The), 3.50%, 4/1/25 468,000  515,738 
Goldman Sachs Group, Inc. (The), 3.50%, 11/16/26 1,058,000  1,172,087 
Goldman Sachs Group, Inc. (The), 2.60%, 2/7/30 445,000  469,844 
Golub Capital BDC, Inc., 3.375%, 4/15/24 595,000  593,874 
Intercontinental Exchange, Inc., 1.85%, 9/15/32 280,000  277,438 
Morgan Stanley, 4.875%, 11/1/22 327,000  353,904 
Morgan Stanley, VRN, 2.19%, 4/28/26 1,205,000  1,263,406 
Oaktree Specialty Lending Corp., 3.50%, 2/25/25 210,000  210,435 
Owl Rock Technology Finance Corp., 4.75%, 12/15/25(3)
540,000  536,132 
UBS Group AG, 4.125%, 9/24/25(3)
200,000  227,659 
7,692,674 
Chemicals — 0.2%
CF Industries, Inc., 4.50%, 12/1/26(3)
300,000  352,014 
17



Shares/
Principal Amount
Value
CF Industries, Inc., 5.15%, 3/15/34 $ 230,000  $ 269,920 
Dow Chemical Co. (The), 3.60%, 11/15/50 550,000  558,395 
LYB International Finance III LLC, 3.375%, 10/1/40 168,000  166,254 
Nutrition & Biosciences, Inc., 1.83%, 10/15/27(3)
177,000  177,370 
1,523,953 
Commercial Services and Supplies — 0.1%
RELX Capital, Inc., 3.00%, 5/22/30 235,000  254,059 
Republic Services, Inc., 2.30%, 3/1/30 508,000  535,615 
Waste Connections, Inc., 2.60%, 2/1/30 580,000  617,192 
1,406,866 
Communications Equipment
Juniper Networks, Inc., 4.50%, 3/15/24 80,000  89,091 
Motorola Solutions, Inc., 2.30%, 11/15/30 290,000  288,416 
377,507 
Construction and Engineering
Quanta Services, Inc., 2.90%, 10/1/30 330,000  344,283 
Construction Materials — 0.1%
Martin Marietta Materials, Inc., 2.50%, 3/15/30 542,000  560,602 
Vulcan Materials Co., 3.50%, 6/1/30 310,000  347,716 
908,318 
Consumer Finance — 0.2%
AerCap Ireland Capital DAC / AerCap Global Aviation Trust, 3.15%, 2/15/24 355,000  352,947 
Capital One Bank USA N.A., 3.375%, 2/15/23 250,000  264,864 
Park Aerospace Holdings Ltd., 5.50%, 2/15/24(3)
370,000  382,517 
Synchrony Financial, 2.85%, 7/25/22 533,000  550,074 
1,550,402 
Containers and Packaging
Ball Corp., 2.875%, 8/15/30 150,000  148,500 
Diversified Consumer Services
Pepperdine University, 3.30%, 12/1/59 355,000  373,165 
Diversified Financial Services — 0.1%
Block Financial LLC, 3.875%, 8/15/30 140,000  144,384 
Equitable Holdings, Inc., 5.00%, 4/20/48 204,000  243,928 
GE Capital Funding LLC, 4.40%, 5/15/30(3)
610,000  665,275 
NatWest Markets plc, 2.375%, 5/21/23(3)
200,000  207,155 
1,260,742 
Diversified Telecommunication Services — 0.5%
AT&T, Inc., 2.30%, 6/1/27 140,000  145,478 
AT&T, Inc., 4.10%, 2/15/28 150,000  172,087 
AT&T, Inc., 2.75%, 6/1/31 835,000  866,498 
AT&T, Inc., 3.50%, 6/1/41 100,000  101,203 
AT&T, Inc., 3.30%, 2/1/52 818,000  755,142 
AT&T, Inc., 3.55%, 9/15/55(3)
173,000  164,358 
Deutsche Telekom International Finance BV, 1.95%, 9/19/21(3)
354,000  358,070 
Deutsche Telekom International Finance BV, 3.60%, 1/19/27(3)
140,000  156,567 
Telefonica Emisiones SA, 5.46%, 2/16/21 100,000  101,420 
Verizon Communications, Inc., 4.40%, 11/1/34 898,000  1,108,625 
Verizon Communications, Inc., 2.99%, 10/30/56(3)
360,000  364,577 
4,294,025 
Electric Utilities — 0.8%
AEP Texas, Inc., 2.10%, 7/1/30 340,000  350,492 
18



Shares/
Principal Amount
Value
AEP Transmission Co. LLC, 3.75%, 12/1/47 $ 100,000  $ 117,438 
American Electric Power Co., Inc., 3.20%, 11/13/27 110,000  120,106 
Berkshire Hathaway Energy Co., 3.50%, 2/1/25 160,000  176,679 
Berkshire Hathaway Energy Co., 3.80%, 7/15/48 150,000  172,289 
Commonwealth Edison Co., 3.20%, 11/15/49 215,000  233,317 
DTE Electric Co., 2.25%, 3/1/30 330,000  347,521 
Duke Energy Florida LLC, 1.75%, 6/15/30 370,000  374,659 
Duke Energy Florida LLC, 3.85%, 11/15/42 220,000  254,034 
Duke Energy Progress LLC, 4.15%, 12/1/44 130,000  158,904 
Duke Energy Progress LLC, 3.70%, 10/15/46 270,000  312,362 
EDP Finance BV, 1.71%, 1/24/28(3)
500,000  494,858 
Entergy Arkansas LLC, 2.65%, 6/15/51 180,000  178,017 
Entergy Texas, Inc., 1.75%, 3/15/31 670,000  659,864 
Exelon Corp., 4.45%, 4/15/46 150,000  181,780 
FirstEnergy Corp., 4.85%, 7/15/47 90,000  97,805 
Florida Power & Light Co., 4.125%, 2/1/42 140,000  172,486 
Florida Power & Light Co., 3.15%, 10/1/49 170,000  189,476 
MidAmerican Energy Co., 4.40%, 10/15/44 250,000  314,758 
Nevada Power Co., 2.40%, 5/1/30 231,000  245,852 
NextEra Energy Capital Holdings, Inc., 3.55%, 5/1/27 290,000  325,873 
NextEra Energy Operating Partners LP, 4.50%, 9/15/27(3)
120,000  131,400 
Northern States Power Co., 2.60%, 6/1/51 160,000  160,880 
Oncor Electric Delivery Co. LLC, 3.10%, 9/15/49 170,000  185,918 
PacifiCorp, 2.70%, 9/15/30 99,000  107,941 
PacifiCorp, 3.30%, 3/15/51 310,000  338,702 
Potomac Electric Power Co., 3.60%, 3/15/24 120,000  130,470 
Southern Co. Gas Capital Corp., 1.75%, 1/15/31 360,000  356,467 
Southern Co. Gas Capital Corp., 3.95%, 10/1/46 90,000  100,013 
Xcel Energy, Inc., 3.40%, 6/1/30 330,000  374,820 
7,365,181 
Energy Equipment and Services
Baker Hughes a GE Co. LLC / Baker Hughes Co-Obligor, Inc., 3.14%, 11/7/29 209,000  217,802 
Entertainment — 0.1%
Netflix, Inc., 3.625%, 6/15/25(3)
464,000  482,850 
Netflix, Inc., 4.875%, 4/15/28 325,000  366,057 
Netflix, Inc., 5.875%, 11/15/28 86,000  102,906 
951,813 
Equity Real Estate Investment Trusts (REITs) — 0.8%
Alexandria Real Estate Equities, Inc., 4.70%, 7/1/30 100,000  122,803 
Alexandria Real Estate Equities, Inc., 1.875%, 2/1/33 435,000  423,616 
American Tower Corp., 3.375%, 10/15/26 110,000  121,714 
Brixmor Operating Partnership LP, 4.05%, 7/1/30 220,000  237,867 
CubeSmart LP, 2.00%, 2/15/31 385,000  375,325 
Equinix, Inc., 5.375%, 5/15/27 335,000  365,363 
Essex Portfolio LP, 3.25%, 5/1/23 50,000  52,621 
Healthcare Realty Trust, Inc., 2.40%, 3/15/30 300,000  302,840 
Healthcare Realty Trust, Inc., 2.05%, 3/15/31 160,000  157,074 
Highwoods Realty LP, 2.60%, 2/1/31 290,000  286,958 
Kilroy Realty LP, 3.80%, 1/15/23 130,000  135,287 
Kilroy Realty LP, 2.50%, 11/15/32 400,000  388,553 
Kimco Realty Corp., 2.80%, 10/1/26 240,000  256,930 
19



Shares/
Principal Amount
Value
Kimco Realty Corp., 1.90%, 3/1/28 $ 420,000  $ 414,372 
Lexington Realty Trust, 2.70%, 9/15/30 549,000  554,731 
National Retail Properties, Inc., 2.50%, 4/15/30 544,000  539,778 
Omega Healthcare Investors, Inc., 3.375%, 2/1/31 445,000  429,135 
Realty Income Corp., 3.25%, 1/15/31 140,000  153,202 
Regency Centers LP, 3.70%, 6/15/30 300,000  327,851 
Scentre Group Trust 2, VRN, 4.75%, 9/24/80(3)
320,000  314,799 
Spirit Realty LP, 3.20%, 2/15/31 280,000  279,214 
Ventas Realty LP, 4.40%, 1/15/29 330,000  372,110 
VEREIT Operating Partnership LP, 3.40%, 1/15/28 471,000  494,266 
Welltower, Inc., 2.75%, 1/15/31 330,000  337,540 
7,443,949 
Food and Staples Retailing — 0.2%
Costco Wholesale Corp., 1.60%, 4/20/30 430,000  434,510 
Kroger Co. (The), 3.875%, 10/15/46 350,000  394,152 
Sysco Corp., 5.95%, 4/1/30 700,000  895,124 
Walmart, Inc., 4.05%, 6/29/48 210,000  271,662 
1,995,448 
Food Products — 0.1%
Conagra Brands, Inc., 1.375%, 11/1/27 252,000  249,305 
Mars, Inc., 1.625%, 7/16/32(3)
470,000  460,027 
Mondelez International, Inc., 2.75%, 4/13/30 412,000  444,255 
1,153,587 
Gas Utilities
CenterPoint Energy Resources Corp., 1.75%, 10/1/30 323,000  324,628 
Health Care Equipment and Supplies — 0.2%
Becton Dickinson and Co., 3.73%, 12/15/24 290,000  319,976 
Danaher Corp., 2.60%, 10/1/50 190,000  188,711 
DENTSPLY SIRONA, Inc., 3.25%, 6/1/30 380,000  412,230 
Smith & Nephew plc, 2.03%, 10/14/30 280,000  278,099 
Stryker Corp., 1.95%, 6/15/30 360,000  365,329 
Zimmer Biomet Holdings, Inc., 3.55%, 3/20/30 310,000  343,099 
1,907,444 
Health Care Providers and Services — 0.4%
Anthem, Inc., 2.375%, 1/15/25 100,000  106,124 
Cigna Corp., 2.40%, 3/15/30 330,000  342,163 
CVS Health Corp., 4.30%, 3/25/28 620,000  718,958 
CVS Health Corp., 1.75%, 8/21/30 310,000  300,886 
CVS Health Corp., 4.78%, 3/25/38 160,000  192,886 
Duke University Health System, Inc., 3.92%, 6/1/47 160,000  189,987 
Partners Healthcare System, Inc., 3.19%, 7/1/49 215,000  225,937 
UnitedHealth Group, Inc., 3.75%, 7/15/25 210,000  238,580 
UnitedHealth Group, Inc., 2.00%, 5/15/30 200,000  208,462 
UnitedHealth Group, Inc., 4.75%, 7/15/45 140,000  189,413 
Universal Health Services, Inc., 2.65%, 10/15/30(3)
730,000  729,055 
3,442,451 
Hotels, Restaurants and Leisure — 0.1%
Las Vegas Sands Corp., 3.90%, 8/8/29 230,000  229,669 
Marriott International, Inc., 3.50%, 10/15/32 482,000  476,151 
705,820 
20



Shares/
Principal Amount
Value
Household Durables — 0.1%
D.R. Horton, Inc., 5.75%, 8/15/23 $ 110,000  $ 123,598 
D.R. Horton, Inc., 2.50%, 10/15/24 310,000  327,809 
Lennar Corp., 4.75%, 4/1/21 352,000  355,881 
807,288 
Industrial Conglomerates — 0.1%
Carlisle Cos., Inc., 2.75%, 3/1/30 315,000  333,977 
General Electric Co., 3.625%, 5/1/30 370,000  390,729 
General Electric Co., 4.35%, 5/1/50 180,000  190,580 
915,286 
Insurance — 0.6%
American International Group, Inc., 4.50%, 7/16/44 533,000  639,021 
Athene Global Funding, 2.55%, 6/29/25(3)
270,000  279,575 
Athene Global Funding, 2.45%, 8/20/27(3)
197,000  199,872 
Athene Holding Ltd., 3.50%, 1/15/31 440,000  443,058 
Belrose Funding Trust, 2.33%, 8/15/30(3)
140,000  139,612 
Berkshire Hathaway Finance Corp., 2.85%, 10/15/50 200,000  203,284 
Five Corners Funding Trust II, 2.85%, 5/15/30(3)
601,000  646,906 
Great-West Lifeco US Finance 2020 LP, 0.90%, 8/12/25(3)
474,000  472,214 
Kemper Corp., 2.40%, 9/30/30 240,000  236,388 
Liberty Mutual Group, Inc., 4.50%, 6/15/49(3)
120,000  142,168 
Lincoln National Corp., 4.35%, 3/1/48 327,000  373,911 
Lincoln National Corp., 4.375%, 6/15/50 147,000  171,039 
Markel Corp., 4.90%, 7/1/22 190,000  203,265 
Protective Life Global Funding, 1.74%, 9/21/30(3)
400,000  394,491 
Teachers Insurance & Annuity Association of America, 3.30%, 5/15/50(3)
265,000  270,216 
Unum Group, 4.50%, 3/15/25 280,000  311,658 
WR Berkley Corp., 4.625%, 3/15/22 130,000  137,094 
5,263,772 
Internet and Direct Marketing Retail
Expedia Group, Inc., 3.60%, 12/15/23(3)
396,000  407,460 
IT Services — 0.2%
Fiserv, Inc., 3.50%, 7/1/29 172,000  193,091 
Global Payments, Inc., 3.20%, 8/15/29 340,000  367,952 
International Business Machines Corp., 1.70%, 5/15/27 300,000  306,716 
International Business Machines Corp., 1.95%, 5/15/30 200,000  203,113 
PayPal Holdings, Inc., 2.30%, 6/1/30 399,000  418,997 
1,489,869 
Machinery
Cummins, Inc., 2.60%, 9/1/50 410,000  390,685 
Media — 0.3%
Charter Communications Operating LLC / Charter Communications Operating Capital, 4.20%, 3/15/28 200,000  226,838 
Charter Communications Operating LLC / Charter Communications Operating Capital, 4.80%, 3/1/50 645,000  734,112 
Comcast Corp., 3.30%, 2/1/27 91,000  101,772 
Comcast Corp., 1.95%, 1/15/31 230,000  233,488 
Comcast Corp., 3.20%, 7/15/36 248,000  276,051 
Comcast Corp., 3.75%, 4/1/40 100,000  116,993 
Discovery Communications LLC, 3.625%, 5/15/30 100,000  110,683 
Time Warner Entertainment Co. LP, 8.375%, 3/15/23 311,000  364,270 
21



Shares/
Principal Amount
Value
ViacomCBS, Inc., 4.75%, 5/15/25 $ 425,000  $ 488,029 
ViacomCBS, Inc., 4.375%, 3/15/43 345,000  372,401 
3,024,637 
Metals and Mining — 0.1%
Newcrest Finance Pty Ltd., 4.20%, 5/13/50(3)
170,000  197,485 
Steel Dynamics, Inc., 3.45%, 4/15/30 155,000  170,338 
Steel Dynamics, Inc., 3.25%, 10/15/50 70,000  67,878 
Teck Resources Ltd., 3.90%, 7/15/30(3)
140,000  146,864 
Teck Resources Ltd., 6.25%, 7/15/41 160,000  182,625 
765,190 
Multi-Utilities — 0.3%
Ameren Corp., 3.50%, 1/15/31 430,000  489,795 
CenterPoint Energy, Inc., 4.25%, 11/1/28 369,000  435,578 
Dominion Energy, Inc., 4.90%, 8/1/41 200,000  254,050 
NiSource, Inc., 1.70%, 2/15/31 220,000  215,916 
NiSource, Inc., 5.65%, 2/1/45 140,000  195,438 
Sempra Energy, 2.875%, 10/1/22 200,000  207,284 
Sempra Energy, 3.25%, 6/15/27 180,000  194,512 
Sempra Energy, 4.00%, 2/1/48 100,000  112,607 
WEC Energy Group, Inc., 1.375%, 10/15/27 490,000  489,192 
2,594,372 
Oil, Gas and Consumable Fuels — 0.8%
Aker BP ASA, 3.75%, 1/15/30(3)
510,000  490,251 
Aker BP ASA, 4.00%, 1/15/31(3)
160,000  156,807 
BP Capital Markets America, Inc., 1.75%, 8/10/30 270,000  263,330 
Chevron Corp., 2.00%, 5/11/27 240,000  251,953 
Chevron USA, Inc., 1.02%, 8/12/27 140,000  138,387 
Diamondback Energy, Inc., 3.50%, 12/1/29 400,000  398,449 
Ecopetrol SA, 5.875%, 5/28/45 90,000  98,275 
Energy Transfer Operating LP, 3.60%, 2/1/23 160,000  164,899 
Energy Transfer Operating LP, 4.25%, 3/15/23 370,000  385,618 
Energy Transfer Operating LP, 4.90%, 3/15/35 70,000  68,883 
Enterprise Products Operating LLC, 4.85%, 3/15/44 460,000  523,341 
EOG Resources, Inc., 4.10%, 2/1/21 130,000  131,180 
Equinor ASA, 1.75%, 1/22/26 240,000  249,234 
Equinor ASA, 3.25%, 11/18/49 230,000  235,759 
Exxon Mobil Corp., 1.57%, 4/15/23 390,000  400,947 
Kinder Morgan Energy Partners LP, 6.50%, 9/1/39 210,000  261,474 
MPLX LP, 5.25%, 1/15/25 200,000  206,269 
MPLX LP, 2.65%, 8/15/30 290,000  279,459 
MPLX LP, 4.50%, 4/15/38 120,000  121,570 
Ovintiv, Inc., 6.50%, 2/1/38 90,000  82,209 
Petroleos Mexicanos, 4.875%, 1/24/22 240,000  243,124 
Petroleos Mexicanos, 3.50%, 1/30/23 60,000  58,848 
Petroleos Mexicanos, 6.625%, 6/15/35 50,000  41,256 
Petroleos Mexicanos, 5.50%, 6/27/44 230,000  168,072 
Plains All American Pipeline LP / PAA Finance Corp., 3.80%, 9/15/30 650,000  628,696 
Sabine Pass Liquefaction LLC, 5.625%, 3/1/25 590,000  675,839 
Sunoco Logistics Partners Operations LP, 4.00%, 10/1/27 200,000  204,493 
Transcontinental Gas Pipe Line Co. LLC, 3.25%, 5/15/30(3)
250,000  268,224 
22



Shares/
Principal Amount
Value
Valero Energy Corp., 1.20%, 3/15/24 $ 462,000  $ 452,941 
7,649,787 
Paper and Forest Products
Georgia-Pacific LLC, 2.10%, 4/30/27(3)
370,000  385,417 
Pharmaceuticals — 0.3%
AstraZeneca plc, 1.375%, 8/6/30 200,000  194,449 
Bristol-Myers Squibb Co., 3.25%, 8/15/22 190,000  199,822 
Bristol-Myers Squibb Co., 3.625%, 5/15/24 300,000  329,156 
Royalty Pharma plc, 1.75%, 9/2/27(3)
498,000  495,256 
Royalty Pharma plc, 2.20%, 9/2/30(3)
400,000  394,037 
Upjohn, Inc., 2.70%, 6/22/30(3)
687,000  709,835 
Upjohn, Inc., 4.00%, 6/22/50(3)
129,000  135,753 
2,458,308 
Road and Rail — 0.3%
Ashtead Capital, Inc., 4.125%, 8/15/25(3)
400,000  411,828 
Burlington Northern Santa Fe LLC, 4.95%, 9/15/41 50,000  65,738 
Burlington Northern Santa Fe LLC, 4.15%, 4/1/45 690,000  841,694 
CSX Corp., 3.25%, 6/1/27 380,000  424,928 
Norfolk Southern Corp., 3.05%, 5/15/50 200,000  206,797 
Union Pacific Corp., 2.40%, 2/5/30 270,000  287,739 
Union Pacific Corp., 3.60%, 9/15/37 200,000  225,767 
Union Pacific Corp., MTN, 3.55%, 8/15/39 140,000  156,884 
2,621,375 
Semiconductors and Semiconductor Equipment — 0.1%
Broadcom Corp. / Broadcom Cayman Finance Ltd., 3.125%, 1/15/25 126,000  134,729 
Broadcom, Inc., 3.15%, 11/15/25 420,000  453,286 
Microchip Technology, Inc., 2.67%, 9/1/23(3)
400,000  415,323 
Texas Instruments, Inc., 1.75%, 5/4/30 210,000  214,546 
1,217,884 
Software — 0.1%
Microsoft Corp., 2.53%, 6/1/50 415,000  422,415 
Oracle Corp., 4.00%, 7/15/46 520,000  601,057 
1,023,472 
Specialty Retail — 0.1%
Home Depot, Inc. (The), 2.50%, 4/15/27 280,000  303,362 
Home Depot, Inc. (The), 3.90%, 6/15/47 50,000  60,457 
Home Depot, Inc. (The), 3.35%, 4/15/50 479,000  543,027 
Lowe's Cos., Inc., 1.30%, 4/15/28 391,000  387,411 
1,294,257 
Technology Hardware, Storage and Peripherals — 0.3%
Apple, Inc., 2.55%, 8/20/60 460,000  442,456 
Dell International LLC / EMC Corp., 5.45%, 6/15/23(3)
501,000  551,584 
EMC Corp., 3.375%, 6/1/23 710,000  725,655 
Hewlett Packard Enterprise Co., 1.45%, 4/1/24 395,000  402,425 
Seagate HDD Cayman, 4.875%, 3/1/24 150,000  164,347 
Seagate HDD Cayman, 4.75%, 1/1/25 325,000  357,717 
2,644,184 
Trading Companies and Distributors — 0.1%
Air Lease Corp., MTN, 2.875%, 1/15/26 270,000  267,771 
Aircastle Ltd., 5.25%, 8/11/25(3)
555,000  551,300 
819,071 
23



Shares/
Principal Amount
Value
Water Utilities — 0.1%
Essential Utilities, Inc., 2.70%, 4/15/30 $ 470,000  $ 497,766 
Wireless Telecommunication Services — 0.1%
T-Mobile USA, Inc., 2.55%, 2/15/31(3)
385,000  392,304 
T-Mobile USA, Inc., 3.30%, 2/15/51(3)
200,000  193,432 
Vodafone Group plc, 4.375%, 2/19/43 190,000  224,960 
810,696 
TOTAL CORPORATE BONDS
(Cost $102,951,127)
106,547,843 
U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES — 10.1%
Adjustable-Rate U.S. Government Agency Mortgage-Backed Securities — 0.3%
FHLMC, VRN, 3.39%, (1-year H15T1Y plus 2.25%), 9/1/35 109,056  115,497 
FHLMC, VRN, 3.20%, (12-month LIBOR plus 1.87%), 7/1/36 27,357  28,937 
FHLMC, VRN, 2.41%, (1-year H15T1Y plus 2.14%), 10/1/36 97,502  102,657 
FHLMC, VRN, 3.46%, (1-year H15T1Y plus 2.26%), 4/1/37 104,164  110,086 
FHLMC, VRN, 3.63%, (12-month LIBOR plus 1.80%), 2/1/38 39,463  41,703 
FHLMC, VRN, 3.80%, (12-month LIBOR plus 1.82%), 6/1/38 29,749  31,455 
FHLMC, VRN, 2.78%, (12-month LIBOR plus 1.76%), 9/1/40 20,935  21,840 
FHLMC, VRN, 3.65%, (12-month LIBOR plus 1.88%), 5/1/41 15,632  16,481 
FHLMC, VRN, 3.23%, (12-month LIBOR plus 1.86%), 7/1/41 110,746  116,703 
FHLMC, VRN, 3.64%, (12-month LIBOR plus 1.64%), 2/1/43 15,795  16,208 
FHLMC, VRN, 2.50%, (12-month LIBOR plus 1.62%), 6/1/43 422  425 
FHLMC, VRN, 2.83%, (12-month LIBOR plus 1.65%), 6/1/43 8,278  8,344 
FHLMC, VRN, 2.84%, (12-month LIBOR plus 1.63%), 1/1/44 172,417  179,066 
FHLMC, VRN, 2.59%, (12-month LIBOR plus 1.60%), 6/1/45 124,863  130,056 
FHLMC, VRN, 2.35%, (12-month LIBOR plus 1.63%), 8/1/46 299,182  311,099 
FHLMC, VRN, 3.07%, (12-month LIBOR plus 1.64%), 9/1/47 431,344  449,833 
FNMA, VRN, 2.47%, (6-month LIBOR plus 1.57%), 6/1/35 69,469  72,161 
FNMA, VRN, 2.57%, (6-month LIBOR plus 1.57%), 6/1/35 79,761  82,847 
FNMA, VRN, 2.99%, (1-year H15T1Y plus 2.16%), 3/1/38 82,420  86,883 
FNMA, VRN, 3.69%, (12-month LIBOR plus 1.69%), 1/1/40 9,410  9,824 
FNMA, VRN, 3.81%, (12-month LIBOR plus 1.85%), 3/1/40 13,487  14,162 
FNMA, VRN, 2.63%, (12-month LIBOR plus 1.77%), 10/1/40 26,891  27,892 
FNMA, VRN, 3.12%, (12-month LIBOR plus 1.57%), 3/1/43 54,962  56,910 
FNMA, VRN, 3.18%, (12-month LIBOR plus 1.61%), 3/1/47 348,181  363,189 
FNMA, VRN, 3.14%, (12-month LIBOR plus 1.61%), 4/1/47 209,281  218,446 
FNMA, VRN, 3.24%, (12-month LIBOR plus 1.62%), 5/1/47 279,599  291,668 
2,904,372 
Fixed-Rate U.S. Government Agency Mortgage-Backed Securities — 9.8%
FHLMC, 6.50%, 1/1/28 6,779  7,574 
FHLMC, 5.50%, 12/1/33 63,324  73,248 
FHLMC, 5.00%, 7/1/35 551,165  635,810 
FHLMC, 5.50%, 1/1/38 49,461  57,643 
FHLMC, 6.00%, 8/1/38 32,572  37,858 
FHLMC, 3.50%, 12/1/47 402,655  428,729 
FNMA, 6.50%, 1/1/29 11,549  13,137 
FNMA, 7.50%, 7/1/29 17,858  18,562 
FNMA, 7.50%, 9/1/30 7,186  8,435 
FNMA, 5.00%, 7/1/31 284,076  319,999 
FNMA, 6.50%, 9/1/31 10,589  11,825 
FNMA, 7.00%, 9/1/31 3,369  3,587 
24



Shares/
Principal Amount
Value
FNMA, 6.50%, 1/1/32 $ 12,464  $ 14,275 
FNMA, 6.50%, 8/1/32 12,474  14,235 
FNMA, 5.50%, 6/1/33 41,256  48,495 
FNMA, 5.50%, 7/1/33 59,672  70,133 
FNMA, 5.50%, 8/1/33 127,711  150,336 
FNMA, 5.50%, 9/1/33 79,557  93,770 
FNMA, 5.00%, 11/1/33 205,525  236,816 
FNMA, 3.50%, 3/1/34 251,744  269,215 
FNMA, 5.00%, 4/1/35 268,471  309,341 
FNMA, 5.00%, 2/1/36 171,496  197,843 
FNMA, 5.50%, 4/1/36 63,032  73,845 
FNMA, 5.50%, 5/1/36 122,589  143,664 
FNMA, 5.00%, 11/1/36 455,622  525,845 
FNMA, 5.50%, 2/1/37 32,707  38,089 
FNMA, 6.00%, 7/1/37 255,890  299,860 
FNMA, 6.50%, 8/1/37 21,323  24,690 
FNMA, 5.50%, 7/1/39 206,882  242,353 
FNMA, 5.00%, 4/1/40 489,735  565,375 
FNMA, 5.00%, 6/1/40 390,812  451,021 
FNMA, 4.50%, 8/1/40 595,983  669,788 
FNMA, 4.50%, 9/1/40 1,268,582  1,426,663 
FNMA, 3.50%, 1/1/41 725,952  785,508 
FNMA, 4.00%, 1/1/41 634,715  716,379 
FNMA, 4.00%, 5/1/41 653,436  719,838 
FNMA, 4.50%, 9/1/41 1,188,516  1,337,796 
FNMA, 4.50%, 9/1/41 259,498  292,039 
FNMA, 4.00%, 1/1/42 495,081  545,473 
FNMA, 3.50%, 5/1/42 1,089,177  1,191,705 
FNMA, 3.50%, 6/1/42 366,627  405,302 
FNMA, 6.50%, 8/1/47 7,725  8,349 
FNMA, 6.50%, 9/1/47 15,586  16,796 
FNMA, 6.50%, 9/1/47 751  811 
FNMA, 6.50%, 9/1/47 8,226  8,867 
FNMA, 3.50%, 3/1/48 1,114,226  1,181,255 
FNMA, 4.00%, 6/1/48 3,020,228  3,234,583 
FNMA, 4.50%, 7/1/48 837,300  907,406 
FNMA, 4.00%, 8/1/48 2,462,756  2,632,224 
FNMA, 3.50%, 4/1/49 735,857  775,517 
FNMA, 4.00%, 6/1/49 4,819,451  5,143,280 
FNMA, 3.50%, 9/1/49 1,554,308  1,640,448 
FNMA, 3.00%, 12/1/49 2,164,636  2,264,317 
FNMA, 3.00%, 3/1/50 3,397,250  3,556,612 
FNMA, 3.00%, 3/1/50 1,397,275  1,461,090 
FNMA, 3.00%, 6/1/50 8,068,979  8,463,098 
FNMA, 3.00%, 6/1/50 769,938  805,512 
FNMA, 3.00%, 6/1/50 695,017  727,200 
FNMA, 3.00%, 6/1/50 953,603  1,003,752 
FNMA, 3.00%, 8/1/50 2,841,183  2,983,136 
GNMA, 2.50%, TBA 3,500,000  3,665,703 
GNMA, 3.00%, TBA 3,500,000  3,652,852 
GNMA, 7.00%, 4/20/26 18,669  20,915 
25



Shares/
Principal Amount
Value
GNMA, 7.50%, 8/15/26 $ 12,217  $ 13,804 
GNMA, 7.00%, 2/15/28 3,704  3,718 
GNMA, 7.50%, 2/15/28 2,826  2,837 
GNMA, 7.00%, 12/15/28 5,606  5,628 
GNMA, 7.00%, 5/15/31 26,157  31,093 
GNMA, 5.50%, 11/15/32 79,136  91,754 
GNMA, 4.50%, 5/20/41 229,802  255,891 
GNMA, 4.50%, 6/15/41 277,894  314,288 
GNMA, 3.50%, 6/20/42 503,581  547,034 
GNMA, 4.50%, 11/20/43 311,746  347,393 
GNMA, 3.50%, 3/15/46 2,100,916  2,238,477 
GNMA, 2.50%, 7/20/46 576,470  609,441 
GNMA, 3.00%, 4/20/50 5,326,963  5,575,188 
UMBS, 2.00%, TBA 12,050,000  12,424,209 
UMBS, 2.50%, TBA 3,820,000  3,980,410 
UMBS, 3.00%, TBA 1,000,000  1,045,234 
UMBS, 3.50%, TBA 7,400,000  7,815,238 
92,931,459 
TOTAL U.S. GOVERNMENT AGENCY MORTGAGE-BACKED SECURITIES
(Cost $94,290,220)
95,835,831 
COLLATERALIZED MORTGAGE OBLIGATIONS — 2.8%
Private Sponsor Collateralized Mortgage Obligations — 1.5%
ABN Amro Mortgage Corp., Series 2003-4, Class A4, 5.50%, 3/25/33 9,284  9,701 
Adjustable Rate Mortgage Trust, Series 2004-4, Class 4A1, VRN, 3.21%, 3/25/35 137,741  140,129 
Agate Bay Mortgage Loan Trust, Series 2016-3, Class A3, VRN, 3.50%, 8/25/46(3)
179,780  184,910 
Arroyo Mortgage Trust, Series 2018-1, Class A2, VRN, 4.02%, 4/25/48(3)
1,495,966  1,516,477 
Banc of America Mortgage Trust, Series 2004-E, Class 2A6 SEQ, VRN, 3.60%, 6/25/34 93,823  91,960 
Citigroup Mortgage Loan Trust, Inc., Series 2004-UST1, Class A5, VRN, 2.37%, 8/25/34 263,977  263,109 
Connecticut Avenue Securities Trust, Series 2020-R02, Class 2M2, VRN, 2.15%, (1-month LIBOR plus 2.00%), 1/25/40(3)
600,000  585,374 
Connecticut Avenue Securities Trust, Series 2020-SBT1, Class 2M2, VRN, 3.80%, (1-month LIBOR plus 3.65%), 2/25/40(3)
600,000  574,350 
Countrywide Home Loan Mortgage Pass-Through Trust, Series 2005-17, Class 1A11, 5.50%, 9/25/35 2,186  1,949 
Credit Suisse Mortgage Trust, Series 2017-HL2, Class A3 SEQ, VRN, 3.50%, 10/25/47(3)
151,919  152,799 
Credit Suisse Mortgage Trust, Series 2019-AFC1, Class A1, VRN, 2.57%, 7/25/49(3)
445,786  454,908 
Credit Suisse Mortgage Trust, Series 2020-AFC1, Class A1, VRN, 2.24%, 2/25/50(3)
394,752  400,193 
Credit Suisse Mortgage Trust, Series 2020-NQM1, Class A1, 1.21%, 5/25/65(3)
2,000,000  2,003,059 
Credit Suisse Mortgage Trust, Series 2020-NQM1, Class A2, 1.41%, 5/25/65(3)
1,163,175  1,164,959 
First Horizon Alternative Mortgage Securities Trust, Series 2004-AA4, Class A1, VRN, 2.41%, 10/25/34 157,252  157,931 
Galton Funding Mortgage Trust, Series 2020-H1, Class A1 SEQ, VRN, 2.31%, 1/25/60(3)
626,882  638,269 
26



Shares/
Principal Amount
Value
GSR Mortgage Loan Trust, Series 2004-7, Class 3A1, VRN, 2.82%, 6/25/34 $ 39,631  $ 38,822 
GSR Mortgage Loan Trust, Series 2004-AR5, Class 3A3, VRN, 3.88%, 5/25/34 64,577  62,410 
GSR Mortgage Loan Trust, Series 2005-AR1, Class 3A1, VRN, 3.29%, 1/25/35 98,591  98,552 
Home RE Ltd., Series 2020-1, Class M1B, VRN, 3.39%, (1-month LIBOR plus 3.25%), 10/25/30(3)
950,000  951,187 
JPMorgan Mortgage Trust, Series 2013-1, Class 2A2 SEQ, VRN, 2.50%, 3/25/43(3)
36,043  36,424 
JPMorgan Mortgage Trust, Series 2017-1, Class A2, VRN, 3.50%, 1/25/47(3)
424,329  436,182 
MASTR Adjustable Rate Mortgages Trust, Series 2004-13, Class 3A7, VRN, 3.19%, 11/21/34 121,892  123,990 
Merrill Lynch Mortgage Investors Trust, Series 2005-3, Class 2A, VRN, 2.91%, 11/25/35 71,269  69,536 
Merrill Lynch Mortgage Investors Trust, Series 2005-A2, Class A1, VRN, 3.79%, 2/25/35 108,511  111,974 
New Residential Mortgage Loan Trust, Series 2017-1A, Class A1, VRN, 4.00%, 2/25/57(3)
844,651  917,658 
New Residential Mortgage Loan Trust, Series 2019-NQM2, Class A1 SEQ, VRN, 3.60%, 4/25/49(3)
586,355  593,819 
Oaktown Re V Ltd., Series 2020-2A, Class M1A, VRN, 2.54%,
(1-month LIBOR plus 2.40%), 10/25/30(3)
520,000  520,975 
Sequoia Mortgage Trust, Series 2017-CH1, Class A1, VRN, 4.00%, 8/25/47(3)
345,167  357,842 
Sequoia Mortgage Trust, Series 2018-CH2, Class A12 SEQ, VRN, 4.00%, 6/25/48(3)
403,571  405,899 
Sofi Mortgage Trust, Series 2016-1A, Class 1A4 SEQ, VRN, 3.00%, 11/25/46(3)
169,571  173,303 
Starwood Mortgage Residential Trust, Series 2020-2, Class A1 SEQ, VRN, 2.72%, 4/25/60(3)
855,964  860,376 
Structured Adjustable Rate Mortgage Loan Trust, Series 2004-8, Class 2A1, VRN, 2.95%, 7/25/34 58,365  58,689 
14,157,715 
U.S. Government Agency Collateralized Mortgage Obligations — 1.3%
FHLMC, Series 2013-DN2, Class M2, VRN, 4.40%, (1-month LIBOR plus 4.25%), 11/25/23 590,191  543,650 
FHLMC, Series 2014-DN2, Class M3, VRN, 3.75%, (1-month LIBOR plus 3.60%), 4/25/24 649,843  616,646 
FHLMC, Series 2014-HQ3, Class M3, VRN, 4.90%, (1-month LIBOR plus 4.75%), 10/25/24 232,240  235,630 
FHLMC, Series 2015-DNA3, Class M3F, VRN, 3.85%, (1-month LIBOR plus 3.70%), 4/25/28 314,718  324,566 
FHLMC, Series 2015-HQ2, Class M3, VRN, 3.40%, (1-month LIBOR plus 3.25%), 5/25/25 180,000  183,074 
FHLMC, Series 2016-DNA1, Class M3, VRN, 5.70%, (1-month LIBOR plus 5.55%), 7/25/28 920,948  972,269 
FHLMC, Series 2016-DNA2, Class M3, VRN, 4.80%, (1-month LIBOR plus 4.65%), 10/25/28 470,198  490,446 
FHLMC, Series 2016-DNA3, Class M3, VRN, 5.15%, (1-month LIBOR plus 5.00%), 12/25/28 803,262  845,574 
FHLMC, Series 2016-HQA4, Class M3, VRN, 4.05%, (1-month LIBOR plus 3.90%), 4/25/29 537,043  557,531 
FHLMC, Series 2017-DNA1, Class M2, VRN, 3.40%, (1-month LIBOR plus 3.25%), 7/25/29 822,509  849,622 
FHLMC, Series 2017-DNA2, Class M2, VRN, 3.60%, (1-month LIBOR plus 3.45%), 10/25/29 220,000  227,136 
27



Shares/
Principal Amount
Value
FHLMC, Series 2018-HQA2, Class M2, VRN, 2.45%, (1-month LIBOR plus 2.30%), 10/25/48(3)
$ 150,000  $ 146,462 
FHLMC, Series 2019-DNA2, Class M2, VRN, 2.60%, (1-month LIBOR plus 2.45%), 3/25/49(3)
306,546  302,981 
FHLMC, Series 2019-DNA3, Class M2, VRN, 2.20%, (1-month LIBOR plus 2.05%), 7/25/49(3)
422,912  416,203 
FNMA, Series 2014-C02, Class 1M2, VRN, 2.75%, (1-month LIBOR plus 2.60%), 5/25/24 273,631  242,085 
FNMA, Series 2014-C02, Class 2M2, VRN, 2.75%, (1-month LIBOR plus 2.60%), 5/25/24 396,779  389,707 
FNMA, Series 2014-C03, Class 2M2, VRN, 3.05%, (1-month LIBOR plus 2.90%), 7/25/24 491,568  491,165 
FNMA, Series 2014-C04, Class 1M2, VRN, 5.05%, (1-month LIBOR plus 4.90%), 11/25/24 355,839  370,288 
FNMA, Series 2014-C04, Class 2M2, VRN, 5.15%, (1-month LIBOR plus 5.00%), 11/25/24 139,867  143,546 
FNMA, Series 2015-C03, Class 1M2, VRN, 5.15%, (1-month LIBOR plus 5.00%), 7/25/25 945,638  966,384 
FNMA, Series 2015-C03, Class 2M2, VRN, 5.15%, (1-month LIBOR plus 5.00%), 7/25/25 288,574  296,143 
FNMA, Series 2015-C04, Class 1M2, VRN, 5.85%, (1-month LIBOR plus 5.70%), 4/25/28 492,219  523,444 
FNMA, Series 2015-C04, Class 2M2, VRN, 5.70%, (1-month LIBOR plus 5.55%), 4/25/28 403,294  424,916 
FNMA, Series 2016-C01, Class 2M2, VRN, 7.10%, (1-month LIBOR plus 6.95%), 8/25/28 631,313  682,375 
FNMA, Series 2016-C04, Class 1M2, VRN, 4.40%, (1-month LIBOR plus 4.25%), 1/25/29 529,581  549,441 
FNMA, Series 2016-C06, Class 1M2, VRN, 4.40%, (1-month LIBOR plus 4.25%), 4/25/29 262,251  272,248 
12,063,532 
TOTAL COLLATERALIZED MORTGAGE OBLIGATIONS
(Cost $25,888,073)
26,221,247 
COLLATERALIZED LOAN OBLIGATIONS — 1.8%
Anchorage Credit Opportunities CLO 1 Ltd., Series 2019-1A, Class A1, VRN, 2.17%, (3-month LIBOR plus 1.95%), 1/20/32(3)
700,000  692,882 
Ares XLI CLO Ltd., Series 2016-41A, Class AR, VRN, 1.44%,
(3-month LIBOR plus 1.20%), 1/15/29(3)
375,000  374,480 
Bean Creek CLO Ltd., Series 2015-1A, Class AR, VRN, 1.24%,
(3-month LIBOR plus 1.02%), 4/20/31(3)
750,000  739,374 
CBAM Ltd., Series 2019-9A, Class A, VRN, 1.52%, (3-month LIBOR plus 1.28%), 2/12/30(3)
650,000  647,804 
CIFC Funding Ltd., Series 2013-3RA, Class A1, VRN, 1.19%,
(3-month LIBOR plus 0.98%), 4/24/31(3)
450,000  444,555 
Dryden 64 CLO Ltd., Series 2018-64A, Class A, VRN, 1.19%,
(3-month LIBOR plus 0.97%), 4/18/31(3)
550,000  542,368 
Elmwood CLO IV Ltd., Series 2020-1A, Class A, VRN, 1.48%,
(3-month LIBOR plus 1.24%), 4/15/33(3)
1,150,000  1,141,249 
Goldentree Loan Opportunities X Ltd., Series 2015-10A, Class AR, VRN, 1.34%, (3-month LIBOR plus 1.12%), 7/20/31(3)
1,000,000  993,925 
Kayne CLO 6 Ltd., Series 2019-6A, Class A1, VRN, 1.60%,
(3-month LIBOR plus 1.38%), 1/20/33(3)
650,000  651,131 
KKR CLO Ltd., Series 2022A, Class A, VRN, 1.37%, (3-month LIBOR plus 1.15%), 7/20/31(3)
550,000  542,753 
KKR CLO Ltd., Series 2030A, Class A1, VRN, 1.74%, (3-month LIBOR plus 1.50%), 10/17/31(3)
875,000  873,440 
28



Shares/
Principal Amount
Value
Madison Park Funding XXII Ltd., Series 2016-22A, Class A1R, VRN, 1.50%, (3-month LIBOR plus 1.26%), 1/15/33(3)
$ 1,000,000  $ 988,245 
Magnetite VIII Ltd., Series 2014-8A, Class AR2, VRN, 1.22%,
(3-month LIBOR plus 0.98%), 4/15/31(3)
750,000  743,753 
Octagon Investment Partners 45 Ltd., Series 2019-1A, Class A, VRN, 1.57%, (3-month LIBOR plus 1.33%), 10/15/32(3)
750,000  748,263 
Parallel Ltd., Series 2020-1A, Class A1, VRN, 1.98%, (3-month LIBOR plus 1.83%), 7/20/31(3)
1,100,000  1,104,269 
Rockford Tower CLO Ltd., Series 2017-3A, Class A, VRN, 1.41%, (3-month LIBOR plus 1.19%), 10/20/30(3)
650,000  648,132 
Rockford Tower CLO Ltd., Series 2019-2A, Class A, VRN, 1.58%, (3-month LIBOR plus 1.33%), 8/20/32(3)
750,000  746,329 
Silver Creek CLO Ltd., Series 2014-1A, Class AR, VRN, 1.46%,
(3-month LIBOR plus 1.24%), 7/20/30(3)
1,050,000  1,046,704 
Sounds Point CLO IV-R Ltd., Series 2013-3RA, Class A, VRN, 1.37%, (3-month LIBOR plus 1.15%), 4/18/31(3)
885,000  875,717 
Symphony CLO XXII Ltd., Series 2020-22A, Class A1A, VRN, 1.51%, (3-month LIBOR plus 1.29%), 4/18/33(3)
500,000  498,576 
Treman Park CLO Ltd., Series 2015-1A, Class ARR, VRN, 1.29%, (3-month LIBOR plus 1.07%), 10/20/28(3)
750,000  747,580 
Voya CLO Ltd., Series 2013-2A, Class A1R, VRN, 1.18%,
(3-month LIBOR plus 0.97%), 4/25/31(3)
900,000  891,040 
TOTAL COLLATERALIZED LOAN OBLIGATIONS
(Cost $16,717,749)
16,682,569 
ASSET-BACKED SECURITIES — 1.4%
BRE Grand Islander Timeshare Issuer LLC, Series 2017-1A, Class A SEQ, 2.94%, 5/25/29(3)
442,822  450,072 
FirstKey Homes Trust, Series 2020-SFR2, Class D, 1.97%, 10/19/37(3)
1,200,000  1,199,757 
Goodgreen, Series 2018-1A, Class A, VRN, 3.93%, 10/15/53(3)
544,264  581,021 
Goodgreen, Series 2020-1A, Class A SEQ, 2.63%, 4/15/55(3)
990,076  992,852 
Hilton Grand Vacations Trust, Series 2018-AA, Class B, 3.70%, 2/25/32(3)
1,053,103  1,091,880 
MVW Owner Trust, Series 2014-1A, Class A SEQ, 2.25%, 9/22/31(3)
90,977  91,192 
MVW Owner Trust, Series 2015-1A, Class A SEQ, 2.52%, 12/20/32(3)
95,738  96,164 
MVW Owner Trust, Series 2016-1A, Class A SEQ, 2.25%, 12/20/33(3)
150,066  150,544 
MVW Owner Trust, Series 2017-1A, Class A SEQ, 2.42%, 12/20/34(3)
347,600  354,570 
MVW Owner Trust, Series 2018-1A, Class A SEQ, 3.45%, 1/21/36(3)
461,350  478,650 
Progress Residential Trust, Series 2018-SFR3, Class A SEQ, 3.88%, 10/17/35(3)
998,955  1,026,719 
Progress Residential Trust, Series 2018-SFR3, Class B, 4.08%, 10/17/35(3)
2,550,000  2,622,367 
Progress Residential Trust, Series 2019-SFR3, Class A SEQ, 2.27%, 9/17/36(3)
1,145,440  1,169,003 
Sierra Timeshare Receivables Funding LLC, Series 2018-2A, Class A SEQ, 3.50%, 6/20/35(3)
342,228  355,853 
Sierra Timeshare Receivables Funding LLC, Series 2019-2A, Class A SEQ, 2.59%, 5/20/36(3)
534,752  549,687 
Towd Point Mortgage Trust, Series 2017-6, Class A1, VRN, 2.75%, 10/25/57(3)
346,875  358,221 
29



Shares/
Principal Amount
Value
Towd Point Mortgage Trust, Series 2018-1, Class A1 SEQ, VRN, 3.00%, 1/25/58(3)
$ 291,929  $ 304,966 
Towd Point Mortgage Trust, Series 2018-4, Class A1, VRN, 3.00%, 6/25/58(3)
265,238  283,440 
US Airways Pass-Through Trust, Series 2013-1, Class A, 3.95%, 5/15/27 104,849  86,406 
VSE VOI Mortgage LLC, Series 2016-A, Class A SEQ, 2.54%, 7/20/33(3)
225,608  227,044 
VSE VOI Mortgage LLC, Series 2018-A, Class B, 3.72%, 2/20/36(3)
457,517  473,499 
TOTAL ASSET-BACKED SECURITIES
(Cost $12,627,591)
12,943,907 
MUNICIPAL SECURITIES — 0.7%
Bay Area Toll Authority Rev., 6.92%, 4/1/40 295,000  451,332 
California State University Rev., 2.98%, 11/1/51 500,000  514,440 
Energy Northwest Rev., (Bonneville Power Administration), 5.00%, 7/1/39 285,000  370,928 
Foothill-Eastern Transportation Corridor Agency Rev., 4.09%, 1/15/49 275,000  287,601 
Grand Parkway Transportation Corp. Rev., 3.24%, 10/1/52 225,000  227,513 
Houston GO, 3.96%, 3/1/47 120,000  143,766 
Metropolitan Transportation Authority Rev., 6.69%, 11/15/40 105,000  124,752 
Metropolitan Transportation Authority Rev., 6.81%, 11/15/40 60,000  72,034 
Metropolitan Water Reclamation District of Greater Chicago GO, 5.72%, 12/1/38 650,000  903,390 
Missouri Highway & Transportation Commission Rev., 5.45%, 5/1/33 130,000  169,827 
New Jersey Turnpike Authority Rev., 7.41%, 1/1/40 200,000  328,120 
New Jersey Turnpike Authority Rev., 7.10%, 1/1/41 95,000  151,595 
New York City GO, 6.27%, 12/1/37 95,000  139,613 
Ohio Turnpike & Infrastructure Commission Rev., 3.22%, 2/15/48 330,000  333,033 
Ohio Water Development Authority Water Pollution Control Loan Fund Rev., 4.88%, 12/1/34 110,000  132,880 
Port Authority of New York & New Jersey Rev., 4.93%, 10/1/51 50,000  65,316 
Regents of the University of California Medical Center Pooled Rev., 3.26%, 5/15/60 185,000  186,965 
Rutgers The State University of New Jersey Rev., 5.67%, 5/1/40 300,000  398,448 
Sacramento Municipal Utility District Rev., 6.16%, 5/15/36 210,000  295,709 
San Francisco Public Utilities Commission Water Rev., 6.00%, 11/1/40 105,000  145,219 
Santa Clara Valley Transportation Authority Rev., 5.88%, 4/1/32 120,000  153,150 
State of California GO, 4.60%, 4/1/38 355,000  417,093 
State of California GO, 7.55%, 4/1/39 100,000  171,998 
State of California GO, 7.30%, 10/1/39 160,000  258,859 
State of California GO, 7.60%, 11/1/40 80,000  141,862 
State of Washington GO, 5.14%, 8/1/40 20,000  28,614 
University of Texas System (The) Rev., 5.00%, 8/15/40 215,000  317,637 
TOTAL MUNICIPAL SECURITIES
(Cost $5,873,705)
6,931,694 
U.S. GOVERNMENT AGENCY SECURITIES — 0.5%
FHLMC, 0.375%, 9/23/25 1,900,000  1,887,280 
FNMA, 2.125%, 4/24/26 270,000  293,320 
FNMA, 0.75%, 10/8/27 2,000,000  1,987,290 
FNMA, 6.625%, 11/15/30 600,000  909,407 
TOTAL U.S. GOVERNMENT AGENCY SECURITIES
(Cost $4,890,634)
5,077,297 
30



Shares/
Principal Amount
Value
SOVEREIGN GOVERNMENTS AND AGENCIES — 0.3%
Chile
Chile Government International Bond, 3.25%, 9/14/21 $ 100,000  $ 102,151 
Chile Government International Bond, 3.625%, 10/30/42 100,000  112,600 
214,751 
Colombia — 0.1%
Colombia Government International Bond, 4.375%, 7/12/21 310,000  317,767 
Mexico — 0.1%
Mexico Government International Bond, 4.15%, 3/28/27 600,000  669,375 
Peru
Peruvian Government International Bond, 5.625%, 11/18/50 170,000  270,945 
Philippines — 0.1%
Philippine Government International Bond, 4.00%, 1/15/21 300,000  301,459 
Philippine Government International Bond, 6.375%, 10/23/34 150,000  217,508 
518,967 
Poland
Republic of Poland Government International Bond, 5.125%, 4/21/21 140,000  143,337 
Republic of Poland Government International Bond, 3.00%, 3/17/23 140,000  148,644 
291,981 
South Africa
Republic of South Africa Government International Bond, 4.67%, 1/17/24 110,000  114,828 
Uruguay
Uruguay Government International Bond, 4.125%, 11/20/45 120,000  143,700 
TOTAL SOVEREIGN GOVERNMENTS AND AGENCIES
(Cost $2,269,826)
2,542,314 
PREFERRED STOCKS — 0.1%
Banks — 0.1%
JPMorgan Chase & Co., 4.60% 552,000  544,962 
Capital Markets
Morgan Stanley, 3.85% 515,000  495,678 
TOTAL PREFERRED STOCKS
(Cost $996,009)
1,040,640 
TEMPORARY CASH INVESTMENTS — 1.2%
State Street Institutional U.S. Government Money Market Fund, Premier Class
(Cost $11,317,841)
11,317,841  11,317,841 
TOTAL INVESTMENT SECURITIES — 103.0%
(Cost $824,090,512)
972,381,506 
OTHER ASSETS AND LIABILITIES — (3.0)% (27,983,302)
TOTAL NET ASSETS — 100.0% $ 944,398,204 

31



FUTURES CONTRACTS PURCHASED
Reference Entity Contracts Expiration
Date
Notional
Amount
Unrealized
Appreciation
(Depreciation)^
S&P 500 E-Mini 49 December 2020 $ 7,998,515  $ (94,605)
U.S. Treasury 10-Year Notes 30 December 2020 4,146,562  (34,193)
U.S. Treasury 2-Year Notes 5 December 2020 1,104,219  (167)
U.S. Treasury 5-Year Notes 22 December 2020 2,763,234  (7,831)
U.S. Treasury Long Bonds 2 December 2020 344,938  (8,192)
U.S. Treasury Ultra Bonds 11 December 2020 2,365,000  (61,712)
$ 18,722,468  $ (206,700)

FUTURES CONTRACTS SOLD
Reference Entity Contracts Expiration
Date
Notional
Amount
Unrealized
Appreciation
(Depreciation)^
U.S. Treasury 10-Year Ultra Notes 73 December 2020 $ 11,481,531  $ 165,729 

^Amount represents value and unrealized appreciation (depreciation).


CENTRALLY CLEARED TOTAL RETURN SWAP AGREEMENTS
Floating Rate Index Pay/Receive Floating
Rate Index
at Termination
Fixed
Rate
Termination
Date
Notional
Amount
Premiums Paid (Received) Unrealized
Appreciation
(Depreciation)
Value
CPURNSA Receive 1.78% 8/5/24 $ 3,500,000 $ (528) $ (37,269) $ (37,797)


32



NOTES TO SCHEDULE OF INVESTMENTS
CPURNSA - U.S. Consumer Price Index Urban Consumers Not Seasonally Adjusted Index
FHLMC - Federal Home Loan Mortgage Corporation
FNMA - Federal National Mortgage Association
GNMA - Government National Mortgage Association
GO - General Obligation
H15T1Y - Constant Maturity U.S. Treasury Note Yield Curve Rate Index
LIBOR - London Interbank Offered Rate
MTN - Medium Term Note
SEQ - Sequential Payer
TBA - To-Be-Announced. Security was purchased on a forward commitment basis with an approximate principal amount and maturity date. Actual principal amount and maturity date will be determined upon settlement.
UMBS - Uniform Mortgage-Backed Securities
VRN - Variable Rate Note. The rate adjusts periodically based upon the terms set forth in the security’s offering documents. The rate shown is effective at the period end and the reference rate and spread, if any, is indicated. The security's effective maturity date may be shorter than the final maturity date shown.
Category is less than 0.05% of total net assets.
(1)Non-income producing.
(2)Security, or a portion thereof, has been pledged at the custodian bank or with a broker for collateral requirements on forward commitments, futures contracts and/or swap agreements. At the period end, the aggregate value of securities pledged was $586,274.
(3)Security was purchased pursuant to Rule 144A under the Securities Act of 1933 and may be sold in transactions exempt from registration, normally to qualified institutional investors. The aggregate value of these securities at the period end was $63,392,025, which represented 6.7% of total net assets.


See Notes to Financial Statements.
33



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $824,090,512) $ 972,381,506 
Cash 3,885
Deposits with broker for futures contracts 588,000
Receivable for investments sold 13,726,561
Receivable for capital shares sold 715,519
Receivable for variation margin on futures contracts 11,844
Receivable for variation margin on swap agreements 5,886
Dividends and interest receivable 2,526,379
989,959,580 
Liabilities
Payable for investments purchased 43,621,104 
Payable for capital shares redeemed 1,022,876
Payable for variation margin on futures contracts 189,749
Payable for variation margin on swap agreements 1,782
Accrued management fees 725,865
45,561,376
Net Assets $ 944,398,204 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 749,949,800 
Distributable earnings 194,448,404
$ 944,398,204 

Net Assets Shares Outstanding Net Asset Value
Per Share
Investor Class, $0.01 Par Value $841,328,378 42,647,709 $19.73
I Class, $0.01 Par Value $99,524,377 5,041,363 $19.74
R5 Class, $0.01 Par Value $3,545,449 179,617 $19.74


See Notes to Financial Statements.
34



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $689) $ 9,257,131 
Interest 8,673,947 
17,931,078 
Expenses:
Management fees 8,163,813 
Directors' fees and expenses 29,948 
Other expenses 7,548 
8,201,309 
Net investment income (loss) 9,729,769 
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 49,148,714 
Futures contract transactions 2,455,318 
Swap agreement transactions 1,790,674 
53,394,706 
Change in net unrealized appreciation (depreciation) on:
Investments 2,645,261 
Futures contracts (50,492)
Swap agreements (4,541)
2,590,228 
Net realized and unrealized gain (loss) 55,984,934 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 65,714,703 


See Notes to Financial Statements.
35



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets
October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ 9,729,769  $ 14,020,828 
Net realized gain (loss) 53,394,706  32,088,158 
Change in net unrealized appreciation (depreciation) 2,590,228  52,232,418 
Net increase (decrease) in net assets resulting from operations 65,714,703  98,341,404 
Distributions to Shareholders
From earnings:
Investor Class (40,169,645) (56,693,821)
I Class (3,755,952) (4,432,562)
R5 Class (156,553) (189,961)
Decrease in net assets from distributions (44,082,150) (61,316,344)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) 12,514,699  10,455,267 
Net increase (decrease) in net assets 34,147,252  47,480,327 
Net Assets
Beginning of period 910,250,952  862,770,625 
End of period $ 944,398,204  $ 910,250,952 


See Notes to Financial Statements.
36



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Balanced Fund (the fund) is one fund in a series issued by the corporation. The fund’s investment objective is to seek long-term capital growth and current income by investing approximately 60% of its assets in equity securities and the remainder in bonds and other fixed-income securities. The fund offers the Investor Class, I Class and R5 Class.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price.
Fixed income securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. Corporate bonds, U.S. Treasury and Government Agency securities, convertible bonds, bank loan obligations, municipal securities, and sovereign governments and agencies are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information. Mortgage-related and asset-backed securities are valued based on models that consider trade data, prepayment and default projections, benchmark yield and spread data and estimated cash flows of each tranche of the issuer. Collateralized loan obligations are valued based on discounted cash flow models that consider trade and economic data, prepayment assumptions and default projections.
Hybrid securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. Preferred stocks and convertible preferred stocks with perpetual maturities are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information.
Open-end management investment companies are valued at the reported net asset value per share. Exchange-traded futures contracts are valued at the settlement price as provided by the appropriate exchange. Swap agreements are valued at an evaluated mean as provided by independent pricing services or independent brokers.

37



If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.
The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes paydown gain (loss) and accretion of discounts and amortization of premiums. Inflation adjustments related to inflation-linked debt securities are reflected as interest income.
Forward Commitments — The fund may engage in securities transactions on a forward commitment basis. In these transactions, the securities’ prices and yields are fixed on the date of the commitment. The fund may sell a to-be-announced (TBA) security and at the same time make a commitment to purchase the same security at a future date at a specified price. Conversely, the fund may purchase a TBA security and at the same time make a commitment to sell the same security at a future date at a specified price. These types of transactions are known as “TBA roll” transactions and are accounted for as purchases and sales. The fund will segregate cash, cash equivalents or other appropriate liquid securities on its records in amounts sufficient to meet the purchase price.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. American Century Investment Management, Inc. (ACIM) (the investment advisor) monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.
Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.

38



Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.
Distributions to Shareholders — Distributions from net investment income, if any, are generally declared and paid quarterly. Distributions from net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc., and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC.
Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), and extraordinary expenses. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets).

The management fee schedule range and the effective annual management fee for each class for the period ended October 31, 2020 are as follows:
Management Fee
Schedule Range
Effective Annual
Management Fee
Investor Class 0.800% to 0.900% 0.90%
I Class 0.600% to 0.700% 0.70%
R5 Class 0.600% to 0.700% 0.70%

Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.
Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $33,338,077 and $19,270,223, respectively. The effect of interfund transactions on the Statement of Operations was $1,451,267 in net realized gain (loss) on investment transactions.

39



4. Investment Transactions

Purchases of investment securities, excluding short-term investments, for the period ended October 31, 2020 totaled $1,526,847,714, of which $554,653,116 represented U.S. Treasury and Government Agency obligations.

Sales of investment securities, excluding short-term investments, for the period ended October 31, 2020 totaled $1,503,317,756, of which $512,700,617 represented U.S. Treasury and Government Agency obligations.

5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019
Shares Amount Shares Amount
Investor Class/Shares Authorized 530,000,000  530,000,000 
Sold 4,046,798  $ 78,184,412  3,650,691  $ 67,082,586 
Issued in reinvestment of distributions 2,048,400  39,160,124  3,226,922  55,463,226 
Redeemed (6,997,025) (132,646,617) (6,358,619) (116,495,515)
(901,827) (15,302,081) 518,994  6,050,297 
I Class/Shares Authorized 50,000,000  50,000,000 
Sold 2,500,437  47,238,943  852,801  15,760,666 
Issued in reinvestment of distributions 196,097  3,754,687  257,104  4,432,356 
Redeemed (1,231,351) (23,595,556) (878,313) (16,141,605)
1,465,183  27,398,074  231,592  4,051,417 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold 26,145  502,174  12,932  239,892 
Issued in reinvestment of distributions 8,180  156,553  11,020  189,961 
Redeemed (13,204) (240,021) (4,163) (76,300)
21,121  418,706  19,789  353,553 
Net increase (decrease) 584,477  $ 12,514,699  770,375  $ 10,455,267 

6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.

40



The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 557,742,242  —  — 
U.S. Treasury Securities —  $ 129,498,081  — 
Corporate Bonds —  106,547,843  — 
U.S. Government Agency Mortgage-Backed Securities —  95,835,831  — 
Collateralized Mortgage Obligations —  26,221,247  — 
Collateralized Loan Obligations —  16,682,569  — 
Asset-Backed Securities —  12,943,907  — 
Municipal Securities —  6,931,694  — 
U.S. Government Agency Securities —  5,077,297  — 
Sovereign Governments and Agencies —  2,542,314  — 
Preferred Stocks —  1,040,640  — 
Temporary Cash Investments 11,317,841  —  — 
$ 569,060,083  $ 403,321,423  — 
Other Financial Instruments
Futures Contracts $ 165,729  —  — 
Liabilities
Other Financial Instruments
Futures Contracts $ 206,700  —  — 
Swap Agreements —  $ 37,797  — 
$ 206,700  $ 37,797  — 

7. Derivative Instruments

Credit Risk — The fund is subject to credit risk in the normal course of pursuing its investment objectives. The value of a bond generally declines as the credit quality of its issuer declines. Credit default swap agreements enable a fund to buy/sell protection against a credit event of a specific issuer or index. A fund may attempt to enhance returns by selling protection or attempt to mitigate credit risk by buying protection. The buyer/seller of credit protection against a security or basket of securities may pay/receive an up-front or periodic payment to compensate for/against potential default events. Changes in value, including the periodic amounts of interest to be paid or received on swap agreements, are recorded as unrealized appreciation (depreciation) on swap agreements. Upon entering into a centrally cleared swap, a fund is required to deposit cash or securities (initial margin) with a financial intermediary in an amount equal to a certain percentage of the notional amount. Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the value and is a component of unrealized gains and losses. Realized gain or loss is recorded upon receipt or payment of a periodic settlement or termination of swap agreements. Net realized and unrealized gains or losses occurring during the holding period of swap agreements are a component of net realized gain (loss) on swap agreement transactions and change in net unrealized appreciation (depreciation) on swap agreements, respectively. The risks of entering into swap agreements include the possible lack of liquidity, failure of the counterparty to meet its obligations, and that there may be unfavorable changes in the underlying investments or instruments. The fund's average notional amount held during the period was $12,686,250.

41



Equity Price Risk — The fund is subject to equity price risk in the normal course of pursuing its investment objectives. A fund may enter into futures contracts based on an equity index in order to manage its exposure to changes in market conditions. A fund may purchase futures contracts to gain exposure to increases in market value or sell futures contracts to protect against a decline in market value. Upon entering into a futures contract, a fund is required to deposit either cash or securities in an amount equal to a certain percentage of the contract value (initial margin). Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the contract value and is recorded as unrealized gains and losses. A fund recognizes a realized gain or loss when the contract is closed or expires. Net realized and unrealized gains or losses occurring during the holding period of futures contracts are a component of net realized gain (loss) on futures contract transactions and change in net unrealized appreciation (depreciation) on futures contracts, respectively. One of the risks of entering into futures contracts is the possibility that the change in value of the contract may not correlate with the changes in value of the underlying securities. The fund's average notional exposure to equity price risk derivative instruments held during the period was $15,538,919 futures contracts purchased.
Interest Rate Risk — The fund is subject to interest rate risk in the normal course of pursuing its investment objectives. The value of bonds generally declines as interest rates rise. A fund may enter into futures contracts based on a bond index or a specific underlying security. A fund may purchase futures contracts to gain exposure to increases in market value or sell futures contracts to protect against a decline in market value. Upon entering into a futures contract, a fund will segregate cash, cash equivalents or other appropriate liquid securities on its records in amounts sufficient to meet requirements. Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the contract value and is recorded as unrealized gains and losses. A fund recognizes a realized gain or loss when the futures contract is closed or expires. Net realized and unrealized gains or losses occurring during the holding period of futures contracts are a component of net realized gain (loss) on futures contract transactions and change in net unrealized appreciation (depreciation) on futures contracts, respectively. One of the risks of entering into futures contracts is the possibility that the change in value of the contract may not correlate with the changes in value of the underlying securities. The fund's average notional exposure to interest rate risk derivative instruments held during the period was $11,029,456 futures contracts purchased and $7,647,740 futures contracts sold.
Other Contracts — A fund may enter into total return swap agreements in order to attempt to obtain or preserve a particular return or spread at a lower cost than obtaining a return or spread through purchases and/or sales of instruments in other markets or gain exposure to certain markets in the most economical way possible. A fund will segregate cash, cash equivalents or other appropriate liquid securities on its records in amounts sufficient to meet requirements. Changes in value, including the periodic amounts of interest to be paid or received on swap agreements, are recorded as unrealized appreciation (depreciation) on swap agreements. Upon entering into a centrally cleared swap, a fund is required to deposit cash or securities (initial margin) with a financial intermediary in an amount equal to a certain percentage of the notional amount. Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the value and is a component of unrealized gains and losses. Realized gain or loss is recorded upon receipt or payment of a periodic settlement or termination of swap agreements. Net realized and unrealized gains or losses occurring during the holding period of swap agreements are a component of net realized gain (loss) on swap agreement transactions and change in net unrealized appreciation (depreciation) on swap agreements, respectively. The risks of entering into swap agreements include the possible lack of liquidity, failure of the counterparty to meet its obligations, and that there may be unfavorable changes in the underlying investments or instruments, including inflationary risk. The fund's average notional amount held during the period was $3,750,000.

42



Value of Derivative Instruments as of October 31, 2020
Asset Derivatives
Liability Derivatives
Type of Risk Exposure Location on Statement of Assets and Liabilities
Value
Location on Statement of Assets and Liabilities
Value
Credit Risk Receivable for variation margin on swap agreements* $ 5,886  Payable for variation margin on swap agreements* — 
Equity Price Risk Receivable for variation margin on futures contracts* —  Payable for variation margin on futures contracts* $ 189,749 
Interest Rate Risk Receivable for variation margin on futures contracts* 11,844  Payable for variation margin on futures contracts* — 
Other Contracts Receivable for variation margin on swap agreements* —  Payable for variation margin on swap agreements* 1,782 
$ 17,730  $ 191,531 

*Included in the unrealized appreciation (depreciation) on futures contracts or centrally cleared swap agreements, as applicable, as reported in the Schedule of Investments.

Effect of Derivative Instruments on the Statement of Operations for the Year Ended October 31, 2020
Net Realized Gain (Loss)
Change in Net Unrealized
Appreciation (Depreciation)
Type of Risk Exposure Location on Statement of Operations
Value
Location on Statement of Operations
Value
Credit Risk Net realized gain (loss) on swap agreement transactions $ 1,744,488  Change in net unrealized appreciation (depreciation) on swap agreements — 
Equity Price Risk Net realized gain (loss) on futures contract transactions 2,092,402  Change in net unrealized appreciation (depreciation) on futures contracts $ (172,328)
Interest Rate Risk Net realized gain (loss) on futures contract transactions 362,916  Change in net unrealized appreciation (depreciation) on futures contracts 121,836 
Other Contracts Net realized gain (loss) on swap agreement transactions 46,186  Change in net unrealized appreciation (depreciation) on swap agreements (4,541)
$ 4,245,992  $ (55,033)

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.
The fund may invest in instruments that have variable or floating coupon rates based on the London Interbank Offered Rate (LIBOR). LIBOR is a benchmark interest rate intended to be representative of the rate at which certain major international banks lend to one another over short-terms. LIBOR will be phased out by the end of 2021. Uncertainty remains regarding a replacement rate or rates for LIBOR. The transition process may lead to increased volatility or illiquidity in markets for instruments that rely on LIBOR. This could result in a change to the value of such instruments.
The fund’s investment process may result in high portfolio turnover, which could mean high transaction costs, affecting both performance and capital gains tax liabilities to investors.

43



9. Federal Tax Information

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 13,199,357  $ 23,646,494 
Long-term capital gains $ 30,882,793  $ 37,669,850 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:
Federal tax cost of investments $ 827,748,786 
Gross tax appreciation of investments $ 157,525,440 
Gross tax depreciation of investments (12,892,720)
Net tax appreciation (depreciation) of investments 144,632,720 
Net tax appreciation (depreciation) on derivatives (37,088)
Net tax appreciation (depreciation) $ 144,595,632 
Other book-to-tax adjustments $ (147,604)
Undistributed ordinary income $ 679,052 
Accumulated long-term gains $ 49,321,324 

The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales. Other book-to-tax adjustments are attributable primarily to the tax deferral of losses on straddle positions.

44



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
    Income From Investment Operations: Distributions From:     Ratio to Average Net Assets of:    
  Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)(1)
Net
Realized and Unrealized
Gain (Loss)
Total From Investment Operations Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net
Asset Value,
End of Period
Total
Return(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net Assets,
End of Period
(in thousands)
Investor Class
2020 $19.25 0.20 1.22 1.42 (0.25) (0.69) (0.94) $19.73 7.54% 0.90% 1.03% 165% $841,328 
2019 $18.55 0.29 1.73 2.02 (0.29) (1.03) (1.32) $19.25 11.82% 0.90% 1.58% 101% $838,309 
2018 $19.31 0.25 0.09 0.34 (0.25) (0.85) (1.10) $18.55 1.72% 0.90% 1.32% 115% $798,120 
2017 $17.39 0.26 2.10 2.36 (0.28) (0.16) (0.44) $19.31 13.78% 0.91% 1.44% 112% $814,569 
2016 $17.91 0.25 0.26 0.51 (0.26) (0.77) (1.03) $17.39 3.14% 0.90% 1.44% 104% $754,957 
I Class
2020 $19.26 0.23 1.23 1.46 (0.29) (0.69) (0.98) $19.74 7.75% 0.70% 1.23% 165% $99,524 
2019 $18.56 0.33 1.72 2.05 (0.32) (1.03) (1.35) $19.26 12.04% 0.70% 1.78% 101% $68,889 
2018 $19.32 0.29 0.09 0.38 (0.29) (0.85) (1.14) $18.56 1.92% 0.70% 1.52% 115% $62,077 
2017 $17.40 0.30 2.09 2.39 (0.31) (0.16) (0.47) $19.32 13.99% 0.71% 1.64% 112% $73,385 
2016 $17.92 0.28 0.27 0.55 (0.30) (0.77) (1.07) $17.40 3.35% 0.70% 1.64% 104% $58,915 
R5 Class
2020 $19.26 0.24 1.22 1.46 (0.29) (0.69) (0.98) $19.74 7.75% 0.70% 1.23% 165% $3,545 
2019 $18.56 0.33 1.72 2.05 (0.32) (1.03) (1.35) $19.26 12.04% 0.70% 1.78% 101% $3,053 
2018 $19.32 0.30 0.08 0.38 (0.29) (0.85) (1.14) $18.56 1.93% 0.70% 1.52% 115% $2,574 
2017(3)
$18.18 0.17 1.14 1.31 (0.17) (0.17) $19.32 7.21%
0.71%(4)
1.66%(4)
112%(5)
$5 




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day. Total returns for periods less than one year are not annualized.
(3)April 10, 2017 (commencement of sale) through October 31, 2017.
(4)Annualized.
(5)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Balanced Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Balanced Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.

47



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
48



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
49



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





50



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
51



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was below its benchmark for the one-, three-, five-, and ten-year periods reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
52



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was below the median of the total expense ratios of the Fund’s peer expense universe.
53



The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
54



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



55




Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for
the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $8,713,623, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $35,208,176, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund hereby designates $1,230,969 as qualified short-term capital gain distributions for purposes of Internal Revenue Code Section 871 for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $4,325,383 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).





































56
































































IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
Business, Not-For-Profit, Employer-Sponsored Retirement Plans 1-800-345-3533
Banks and Trust Companies, Broker-Dealers, Financial Professionals, Insurance Companies 1-800-345-6488
Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90968 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Growth Fund
Investor Class (TWCGX)
I Class (TWGIX)
Y Class (AGYWX)
A Class (TCRAX)
C Class (TWRCX)
R Class (AGWRX)
R5 Class (AGWUX)
R6 Class (AGRDX)
















Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
14
Statement of Operations
15
Statement of Changes in Net Assets
16
Notes to Financial Statements
17
Financial Highlights
25
Report of Independent Registered Public Accounting Firm
29
Management
30
Approval of Management Agreement
33
Additional Information
37





















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance

Total Returns as of October 31, 2020
      Average Annual Returns  
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class TWCGX 26.70% 15.89% 14.57% 6/30/71
Russell 1000 Growth Index 29.22% 17.30% 16.29%
I Class TWGIX 26.93% 16.13% 14.80% 6/16/97
Y Class AGYWX 27.15% 19.52% 4/10/17
A Class TCRAX 6/4/97
No sales charge 26.38% 15.61% 14.29%
With sales charge 19.10% 14.25% 13.61%
C Class TWRCX 25.43% 14.75% 13.43% 3/1/10
R Class AGWRX 26.07% 15.32% 14.00% 8/29/03
R5 Class AGWUX 26.94% 19.33% 4/10/17
R6 Class AGRDX 27.13% 16.31% 15.54% 7/26/13
Average annual returns since inception are presented when ten years of performance history is not available.
Although the fund’s actual inception date was October 31, 1958, the Investor Class inception date corresponds with the investment advisor’s implementation of its current investment philosophy and practices.

Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.


















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-9707926FF40F49CAA6E1.JPG
Value on October 31, 2020
Investor Class — $39,014
Russell 1000 Growth Index — $45,290

Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class
0.98% 0.78% 0.63% 1.23% 1.98% 1.48% 0.78% 0.63%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.

















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary

Portfolio Managers: Gregory Woodhams, Justin Brown and Scott Marolf

Senior financial analyst Scott Marolf was added to the fund’s portfolio management team in February of 2020.

Performance Summary

Growth returned 26.70%* for the 12 months ended October 31, 2020, lagging the 29.22% return of the fund’s benchmark, the Russell 1000 Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell 1000 Growth Index, all sectors posted gains except for energy, which struggled with the declining price of oil amid falling demand, and industrials, which declined modestly on concerns about global economic weakness. Consumer discretionary and information technology led the benchmark’s performance.

Stock selection in the health care, communication services and consumer discretionary sectors detracted from fund performance relative to the benchmark. Stock decisions in the industrials and information technology sectors benefited relative performance, as did underweighting industrials.

Health Care and Communication Services Stocks Led Detractors

Stock selection in the health care equipment and supplies industry weighed on relative performance in the health care sector. The industry felt the effects of stay-at-home mandates due to the pandemic as hospitals and individuals postponed voluntary procedures. In the communication services sector, entertainment companies such as The Walt Disney Co. also struggled. Disney was forced to close its theme parks. The company’s weakness was exacerbated by the impact of delayed movie releases and a lack of live sports on its ESPN network. We maintained a position in Disney based on its growth in streaming and an eventual recovery in its cyclical media and theme park assets.

Significant detractors included Tesla. We were underweight the electric car company relative to the benchmark, and the stock outperformed due to solid fundamental reports and strong demand for its vehicles. Retail investors also reacted positively to the announcement of a five-for-one stock split. Visa underperformed after the payments company reported declining revenues due primarily to weakness in cross-border transactions as a result of pandemic-related travel restrictions. We maintained a position in Visa based on our favorable view on payment networks. We were also underweight Apple, which detracted from performance. The consumer electronics company delivered solid results with strength in most work-from-home categories, including iPads and Macs, as well as solid growth in services. Also, the company split its stock four-for-one to make the equity more appealing to retail investors.

Dow was a significant detractor. The chemicals company faced the perfect storm of lower global gross domestic product having an impact on polyethylene demand and significantly lower oil prices diminishing Dow’s relative feedstock cost advantage. We eliminated our holding. The stock of multibrand restaurant owner Darden Restaurants fell sharply due to the social distancing restrictions implemented to fight the pandemic. We eliminated Darden on our belief it will take longer for some restaurants to fully recovery from the pandemic.



*All fund returns referenced in this commentary are for Investor Class shares. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.
5



Industrials Aided Performance

Stock decisions among aerospace and defense companies and an underweight allocation to the industry benefited relative performance in the industrials sector. Our lighter exposure to The Boeing Co. aided results as the airplane manufacturer and defense contractor was hurt by the sharply reduced air travel, which curtailed demand for its planes. It also faced continuing difficulties with safety issues with its 737 MAX airplane. We eliminated Boeing during the first quarter of 2020.

In the information technology sector, stock selection in IT services helped performance, as did an overweight allocation to semiconductors and semiconductor equipment. Cloud computing firm Fastly was a key contributor. The company provides a variety of services, including a content delivery network that allows companies to cache data and other content that can then be retrieved by end users. Fastly benefited from the stay-at-home environment. PayPal Holdings outperformed. The payment services company reported better-than-expected earnings, helped by increased use of digital payments during the pandemic. Chipmaker NVIDIA reported solid results and guidance due to strength in its data center and gaming businesses. The data center business is being driven by the launch of new products that are based on a new architecture and a leading process node, which is driving better price/performance per chip. The company also announced the proposed acquisition of ARM Holdings, which has the ability to broaden NVIDIA’s reach in semiconductors. Microsoft was a key contributor. The software giant was buoyed by the breadth of its businesses, its transition to a subscription model and strength in its cloud division.

Other top contributors included Amazon. The retailer continued to benefit from the shift of consumer spending trends toward online purchasing. This is especially important for Amazon’s progress with consumables, including grocery and fresh foods, which has been a slower area of progress. Amazon could also benefit from potential rising demand for more cloud usage.

Outlook

We believe stock selection—rather than sector allocation or market timing via the use of cash—is the most efficient means of generating superior risk-adjusted returns. As a result of this approach, the portfolio’s sector and industry selection, as well as capitalization range allocations, are primarily due to identifying what we believe to be superior individual securities.

At period-end, our largest sector allocation relative to the benchmark was information technology. The largest underweight was health care.







6



Fund Characteristics
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Microsoft Corp. 12.0%
Amazon.com, Inc. 9.6%
Apple, Inc. 8.9%
Alphabet, Inc., Class A 6.7%
Visa, Inc., Class A 4.4%
NVIDIA Corp. 3.5%
PayPal Holdings, Inc. 3.4%
Facebook, Inc., Class A 2.8%
Procter & Gamble Co. (The) 2.3%
UnitedHealth Group, Inc. 2.1%
Top Five Industries % of net assets
Software 17.9%
Internet and Direct Marketing Retail 10.8%
Interactive Media and Services 10.2%
IT Services 9.1%
Technology Hardware, Storage and Peripherals 8.9%
Types of Investments in Portfolio % of net assets
Common Stocks 100.0%
Temporary Cash Investments 0.2%
Temporary Cash Investments - Securities Lending Collateral 0.4%
Other Assets and Liabilities (0.6)%
7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.


8



Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
Investor Class $1,000 $1,187.50 $5.33 0.97%
I Class $1,000 $1,188.90 $4.24 0.77%
Y Class $1,000 $1,189.90 $3.41 0.62%
A Class $1,000 $1,186.20 $6.70 1.22%
C Class $1,000 $1,181.80 $10.80 1.97%
R Class $1,000 $1,184.60 $8.07 1.47%
R5 Class $1,000 $1,189.00 $4.24 0.77%
R6 Class $1,000 $1,189.90 $3.41 0.62%
Hypothetical
Investor Class $1,000 $1,020.26 $4.93 0.97%
I Class $1,000 $1,021.27 $3.91 0.77%
Y Class $1,000 $1,022.02 $3.15 0.62%
A Class $1,000 $1,019.00 $6.19 1.22%
C Class $1,000 $1,015.23 $9.98 1.97%
R Class $1,000 $1,017.75 $7.46 1.47%
R5 Class $1,000 $1,021.27 $3.91 0.77%
R6 Class $1,000 $1,022.02 $3.15 0.62%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 100.0%
Aerospace and Defense — 1.0%
Lockheed Martin Corp. 299,600  $ 104,898,948 
Auto Components — 1.2%
Aptiv plc 1,234,222  119,090,081 
Automobiles — 0.7%
Tesla, Inc.(1)
177,660  68,939,186 
Biotechnology — 3.4%
Amgen, Inc. 878,298  190,537,968 
CRISPR Therapeutics AG(1)
528,089  48,489,132 
Vertex Pharmaceuticals, Inc.(1)
530,105  110,452,678 
349,479,778 
Building Products — 1.2%
Masco Corp. 1,872,880  100,386,368 
Trex Co., Inc.(1)
323,214  22,476,302 
122,862,670 
Capital Markets — 1.4%
S&P Global, Inc. 447,603  144,454,916 
Electrical Equipment — 1.5%
Ballard Power Systems, Inc.(1)(2)
2,146,702  31,706,789 
Generac Holdings, Inc.(1)
163,783  34,418,997 
Rockwell Automation, Inc. 377,360  89,479,603 
155,605,389 
Electronic Equipment, Instruments and Components — 1.8%
CDW Corp. 370,386  45,409,324 
Cognex Corp. 886,161  58,398,010 
Keysight Technologies, Inc.(1)
731,988  76,763,581 
180,570,915 
Entertainment — 1.6%
Liberty Media Corp.-Liberty Formula One, Class C(1)
928,783  33,556,930 
Take-Two Interactive Software, Inc.(1)
506,287  78,433,982 
Walt Disney Co. (The) 442,973  53,710,476 
165,701,388 
Equity Real Estate Investment Trusts (REITs) — 1.5%
SBA Communications Corp. 541,026  157,097,720 
Food Products — 1.6%
Beyond Meat, Inc.(1)
172,327  24,544,535 
Mondelez International, Inc., Class A 2,344,921  124,562,203 
Vital Farms, Inc.(1)
424,727  14,678,565 
163,785,303 
Health Care Equipment and Supplies — 2.4%
DexCom, Inc.(1)
164,224  52,482,706 
Edwards Lifesciences Corp.(1)
602,095  43,164,191 
IDEXX Laboratories, Inc.(1)
95,648  40,633,183 
Insulet Corp.(1)
106,438  23,655,846 
Intuitive Surgical, Inc.(1)
134,818  89,934,391 
249,870,317 
10



Shares Value
Health Care Providers and Services — 2.5%
Quest Diagnostics, Inc. 296,567  $ 36,222,693 
UnitedHealth Group, Inc. 708,540  216,203,896 
252,426,589 
Health Care Technology — 0.7%
Teladoc Health, Inc.(1)(2)
227,274  44,650,250 
Veeva Systems, Inc., Class A(1)
99,231  26,797,332 
71,447,582 
Hotels, Restaurants and Leisure — 1.5%
Chipotle Mexican Grill, Inc.(1)
73,841  88,718,485 
Domino's Pizza, Inc. 184,202  69,687,300 
158,405,785 
Household Products — 2.3%
Procter & Gamble Co. (The) 1,750,735  240,025,768 
Insurance — 0.8%
Progressive Corp. (The) 714,781  65,688,374 
Root, Inc., Class A(1)
336,596  8,068,206 
SelectQuote, Inc.(1)
690,817  11,895,869 
85,652,449 
Interactive Media and Services — 10.2%
Alphabet, Inc., Class A(1)
427,980  691,662,758 
Facebook, Inc., Class A(1)
1,103,804  290,421,870 
Twitter, Inc.(1)
1,565,969  64,768,478 
1,046,853,106 
Internet and Direct Marketing Retail — 10.8%
Amazon.com, Inc.(1)
323,461  982,076,115 
Chewy, Inc., Class A(1)(2)
1,160,388  71,479,901 
Expedia Group, Inc. 512,764  48,276,731 
1,101,832,747 
IT Services — 9.1%
Fastly, Inc., Class A(1)(2)
611,453  38,833,380 
Okta, Inc.(1)
145,190  30,465,218 
PayPal Holdings, Inc.(1)
1,881,715  350,243,613 
Snowflake, Inc., Class A(1)
1,119  279,772 
Twilio, Inc., Class A(1)
112,538  31,394,726 
VeriSign, Inc.(1)
164,539  31,377,587 
Visa, Inc., Class A 2,478,887  450,438,557 
933,032,853 
Life Sciences Tools and Services — 0.9%
Adaptive Biotechnologies Corp.(1)
802,071  36,959,432 
Agilent Technologies, Inc. 324,193  33,096,863 
Repligen Corp.(1)
103,549  17,248,157 
87,304,452 
Machinery — 0.4%
Cummins, Inc. 178,859  39,329,305 
Personal Products — 0.6%
Estee Lauder Cos., Inc. (The), Class A 265,930  58,414,184 
Pharmaceuticals — 2.5%
Merck & Co., Inc. 1,025,831  77,152,750 
Novo Nordisk A/S, B Shares 1,690,462  108,108,035 
Zoetis, Inc. 446,733  70,829,517 
256,090,302 
11



Shares Value
Road and Rail — 1.0%
Lyft, Inc., Class A(1)
872,422  $ 19,917,394 
Union Pacific Corp. 478,721  84,824,574 
104,741,968 
Semiconductors and Semiconductor Equipment — 7.8%
Advanced Micro Devices, Inc.(1)
1,284,331  96,697,281 
Analog Devices, Inc. 535,744  63,501,736 
ASML Holding NV 418,290  152,071,291 
Broadcom, Inc. 373,076  130,438,562 
NVIDIA Corp. 710,758  356,345,631 
799,054,501 
Software — 17.9%
Datadog, Inc., Class A(1)
428,746  38,908,699 
DocuSign, Inc.(1)
142,950  28,911,638 
JFrog Ltd.(1)
2,886  209,033 
Microsoft Corp. 6,089,505  1,232,942,077 
PagerDuty, Inc.(1)(2)
1,731,888  46,934,165 
salesforce.com, Inc.(1)
740,380  171,968,063 
Slack Technologies, Inc., Class A(1)
2,715,586  69,464,690 
Splunk, Inc.(1)
517,536  102,492,829 
Workday, Inc., Class A(1)
140,947  29,615,784 
Zendesk, Inc.(1)
989,682  109,795,321 
1,831,242,299 
Specialty Retail — 1.1%
Home Depot, Inc. (The) 184,100  49,101,311 
TJX Cos., Inc. (The) 1,308,516  66,472,613 
115,573,924 
Technology Hardware, Storage and Peripherals — 8.9%
Apple, Inc. 8,398,795  914,292,824 
Textiles, Apparel and Luxury Goods — 1.7%
NIKE, Inc., Class B 1,477,541  177,423,123 
TOTAL COMMON STOCKS
(Cost $5,054,346,348)
10,255,500,372 
TEMPORARY CASH INVESTMENTS — 0.2%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $4,863,049), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $4,784,532) 4,784,508 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 0.125%, 7/15/30, valued at $8,502,792), at 0.06%, dated 10/30/20,
due 11/2/20 (Delivery value $8,336,042)
8,336,000 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $13,120,508)
13,120,508 
TEMPORARY CASH INVESTMENTS - SECURITIES LENDING COLLATERAL(3) — 0.4%
State Street Navigator Securities Lending Government Money Market Portfolio
(Cost $45,480,168)
45,480,168  45,480,168 
TOTAL INVESTMENT SECURITIES — 100.6%
(Cost $5,112,947,024)
10,314,101,048 
OTHER ASSETS AND LIABILITIES — (0.6)% (61,608,224)
TOTAL NET ASSETS — 100.0% $ 10,252,492,824 

12



FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
EUR 3,355,596  USD 3,938,769  Credit Suisse AG 12/31/20 $ (24,977)
EUR 3,205,916  USD 3,807,221  Credit Suisse AG 12/31/20 (68,009)
EUR 3,847,099  USD 4,556,935  Credit Suisse AG 12/31/20 (69,881)
USD 131,405,172  EUR 111,948,519  Credit Suisse AG 12/31/20 834,300 
USD 4,028,172  EUR 3,431,365  Credit Suisse AG 12/31/20 26,008 
USD 6,117,943  EUR 5,205,377  Credit Suisse AG 12/31/20 46,664 
$ 744,105 

NOTES TO SCHEDULE OF INVESTMENTS
EUR - Euro
USD - United States Dollar
(1)Non-income producing.
(2)Security, or a portion thereof, is on loan. At the period end, the aggregate value of securities on loan was $96,342,699. The amount of securities on loan indicated may not correspond with the securities on loan identified because securities with pending sales are in the process of recall from the brokers.
(3)Investment of cash collateral from securities on loan. At the period end, the aggregate value of the collateral held by the fund was $104,215,411, which includes securities collateral of $58,735,243.


See Notes to Financial Statements.
13



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $5,067,466,856) — including $96,342,699 of securities on loan $ 10,268,620,880 
Investment made with cash collateral received for securities on loan, at value
(cost of $45,480,168)
45,480,168 
Total investment securities, at value (cost of $5,112,947,024) 10,314,101,048 
Cash 3,982 
Receivable for investments sold 24,389,033 
Receivable for capital shares sold 2,233,847 
Unrealized appreciation on forward foreign currency exchange contracts 906,972 
Dividends and interest receivable 2,335,316 
Securities lending receivable 53,611 
10,344,023,809 
Liabilities
Payable for collateral received for securities on loan 45,480,168 
Payable for investments purchased 7,105,222 
Payable for capital shares redeemed 30,264,941 
Unrealized depreciation on forward foreign currency exchange contracts 162,867 
Accrued management fees 8,439,091 
Distribution and service fees payable 78,696 
91,530,985 
Net Assets $ 10,252,492,824 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 4,686,285,919 
Distributable earnings 5,566,206,905 
$ 10,252,492,824 

Net Assets Shares Outstanding Net Asset Value Per Share
Investor Class, $0.01 Par Value $7,656,430,242 182,575,405 $41.94
I Class, $0.01 Par Value $1,719,814,040 40,114,634 $42.87
Y Class, $0.01 Par Value $52,045,800 1,212,439 $42.93
A Class, $0.01 Par Value $102,471,636 2,541,170 $40.32*
C Class, $0.01 Par Value $13,527,401 361,966 $37.37
R Class, $0.01 Par Value $96,170,421 2,468,162 $38.96
R5 Class, $0.01 Par Value $433,055 10,091 $42.91
R6 Class, $0.01 Par Value $611,600,229 14,269,375 $42.86
*Maximum offering price $42.78 (net asset value divided by 0.9425).


See Notes to Financial Statements.

14



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $577,249) $ 86,320,362 
Securities lending, net 714,238 
Interest 500,448 
87,535,048 
Expenses:
Management fees 86,155,014 
Distribution and service fees:
A Class 249,749 
C Class 116,628 
R Class 461,912 
Directors' fees and expenses 300,125 
Other expenses 12,669 
87,296,097 
Net investment income (loss) 238,951 
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions (Note 4) 593,469,427 
Forward foreign currency exchange contract transactions (5,567,078)
Futures contract transactions 11,298,722 
Foreign currency translation transactions (4,268)
599,196,803 
Change in net unrealized appreciation (depreciation) on:
Investments 1,537,275,177 
Forward foreign currency exchange contracts 1,123,274 
Futures contracts (1,432,221)
Translation of assets and liabilities in foreign currencies 23,676 
1,536,989,906 
Net realized and unrealized gain (loss) 2,136,186,709 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 2,136,425,660 


See Notes to Financial Statements.

15



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ 238,951  $ 22,124,570 
Net realized gain (loss) 599,196,803  457,660,058 
Change in net unrealized appreciation (depreciation) 1,536,989,906  661,567,516 
Net increase (decrease) in net assets resulting from operations 2,136,425,660  1,141,352,144 
Distributions to Shareholders
From earnings:
Investor Class (480,259,209) (620,549,413)
I Class (114,436,997) (135,799,946)
Y Class (4,514,391) (5,869,002)
A Class (7,229,137) (11,268,612)
C Class (744,058) (1,173,312)
R Class (7,119,319) (11,498,287)
R5 Class (42,460) (45,748)
R6 Class (41,181,311) (48,975,743)
Decrease in net assets from distributions (655,526,882) (835,180,063)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) 728,589,142  (221,312,359)
Net increase (decrease) in net assets 2,209,487,920  84,859,722 
Net Assets
Beginning of period 8,043,004,904  7,958,145,182 
End of period $ 10,252,492,824  $ 8,043,004,904 


See Notes to Financial Statements.

16



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Growth Fund (the fund) is one fund in a series issued by the corporation. The fund's investment objective is to seek long-term capital growth.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.
Fixed income securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. U.S. Treasury and Government Agency securities are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information.
Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Exchange-traded futures contracts are valued at the settlement price as provided by the appropriate exchange. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.

If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.
17



The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.



18



Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.
Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.
Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

The following table reflects a breakdown of transactions accounted for as secured borrowings, the gross obligation by the type of collateral pledged, and the remaining contractual maturity of those transactions as of October 31, 2020.

Remaining Contractual Maturity of Agreements
Overnight and
Continuous
<30 days
Between
30 & 90 days
>90 days
Total
Securities Lending Transactions(1)
Common Stocks $ 45,480,168  —  —  —  $ 45,480,168 
Gross amount of recognized liabilities for securities lending transactions $ 45,480,168 

(1)Amount represents the payable for cash collateral received for securities on loan. This will generally be in the Overnight and Continuous column as the securities are typically callable on demand.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC.








19



Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets). The strategy assets of the fund also include the assets of NT Growth Fund, one fund in a series issued by the corporation.

The management fee schedule range and the effective annual management fee for each class for the period ended October 31, 2020 are as follows:

Management Fee
Schedule Range
Effective Annual
Management Fee
Investor Class 0.800% to 0.990% 0.97%
I Class 0.600% to 0.790% 0.77%
Y Class 0.450% to 0.640% 0.62%
A Class 0.800% to 0.990% 0.97%
C Class 0.800% to 0.990% 0.97%
R Class 0.800% to 0.990% 0.97%
R5 Class 0.600% to 0.790% 0.77%
R6 Class 0.450% to 0.640% 0.62%

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.
Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.
Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $5,791,151 and $5,504,008, respectively. The effect of interfund transactions on the Statement of Operations was $951,221 in net realized gain (loss) on investment transactions.

4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $3,083,934,281 and $4,171,327,811, respectively.

For the period ended October 31, 2020, the fund incurred net realized gains of $9,756,480 from redemptions in kind. A redemption in kind occurs when a fund delivers securities into its portfolio in lieu of cash as payment to a redeeming shareholder.
20



5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019
Shares Amount Shares Amount
Investor Class/Shares Authorized 2,100,000,000  2,100,000,000 
Sold 9,314,651  $ 343,295,401  6,174,389  $ 204,624,318 
Issued in connection with reorganization (Note 10) 33,740,937  1,281,095,913  —  — 
Issued in reinvestment of distributions 12,608,305  463,439,340  20,752,173  599,737,810 
Redeemed (38,931,327) (1,459,424,248) (22,142,478) (738,868,587)
16,732,566  628,406,406  4,784,084  65,493,541 
I Class/Shares Authorized 460,000,000  460,000,000 
Sold 14,389,473  554,081,579  8,201,339  284,251,396 
Issued in connection with reorganization (Note 10) 238,480  9,244,211  —  — 
Issued in reinvestment of distributions 3,019,127  113,217,452  4,549,653  134,032,787 
Redeemed (15,353,587) (606,960,175) (9,493,140) (319,770,751)
2,293,493  69,583,067  3,257,852  98,513,432 
Y Class/Shares Authorized 40,000,000  40,000,000 
Sold 153,010  5,711,874  193,293  6,309,777 
Issued in reinvestment of distributions 119,002  4,461,395  197,540  5,819,520 
Redeemed (524,867) (19,910,740) (401,561) (13,473,502)
(252,855) (9,737,471) (10,728) (1,344,205)
A Class/Shares Authorized 40,000,000  40,000,000 
Sold 683,766  24,686,474  583,026  18,601,566 
Issued in connection with reorganization (Note 10) 422,151  15,436,291  —  — 
Issued in reinvestment of distributions 164,961  5,847,619  335,059  9,354,848 
Redeemed (1,436,368) (51,778,786) (1,260,515) (40,816,895)
(165,490) (5,808,402) (342,430) (12,860,481)
C Class/Shares Authorized 30,000,000  30,000,000 
Sold 74,102  2,515,992  63,391  1,766,765 
Issued in connection with reorganization (Note 10) 124,022  4,225,593  —  — 
Issued in reinvestment of distributions 20,026  661,725  39,522  1,041,792 
Redeemed (115,923) (3,918,628) (149,895) (4,554,998)
102,227  3,484,682  (46,982) (1,746,441)
R Class/Shares Authorized 40,000,000  40,000,000 
Sold 431,377  15,135,430  339,606  10,447,195 
Issued in connection with reorganization (Note 10) 461,820  16,348,203  —  — 
Issued in reinvestment of distributions 205,542  7,043,451  417,329  11,334,663 
Redeemed (1,236,289) (42,445,952) (1,207,308) (36,468,093)
(137,550) (3,918,868) (450,373) (14,686,235)
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold 999  38,826  2,974  101,028 
Issued in reinvestment of distributions 1,135  42,460  1,552  45,748 
Redeemed (6,612) (240,109) (1,305) (44,020)
(4,478) (158,823) 3,221  102,756 
R6 Class/Shares Authorized 200,000,000  200,000,000 
Sold 4,275,401  166,984,195  3,277,264  109,281,671 
Issued in reinvestment of distributions 1,098,511  41,181,311  1,664,709  48,975,743 
Redeemed (4,210,873) (161,426,955) (15,267,638) (513,042,140)
1,163,039  46,738,551  (10,325,665) (354,784,726)
Net increase (decrease) 19,730,952  $ 728,589,142  (3,131,021) $ (221,312,359)
21



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 9,995,321,046  $ 260,179,326  — 
Temporary Cash Investments —  13,120,508  — 
Temporary Cash Investments - Securities Lending Collateral 45,480,168  —  — 
$ 10,040,801,214  $ 273,299,834  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 906,972  — 
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 162,867  — 

7. Derivative Instruments

Equity Price Risk — The fund is subject to equity price risk in the normal course of pursuing its investment objectives. A fund may enter into futures contracts based on an equity index in order to manage its exposure to changes in market conditions. A fund may purchase futures contracts to gain exposure to increases in market value or sell futures contracts to protect against a decline in market value. Upon entering into a futures contract, a fund is required to deposit either cash or securities in an amount equal to a certain percentage of the contract value (initial margin). Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the contract value and is recorded as unrealized gains and losses. A fund recognizes a realized gain or loss when the contract is closed or expires. Net realized and unrealized gains or losses occurring during the holding period of futures contracts are a component of net realized gain (loss) on futures contract transactions and change in net unrealized appreciation (depreciation) on futures contracts, respectively. One of the risks of entering into futures contracts is the possibility that the change in value of the contract may not correlate with the changes in value of the underlying securities. The fund's average notional exposure to equity price risk derivative instruments held during the period was $48,721,867 futures contracts purchased.





22



Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $147,997,212.

Value of Derivative Instruments as of October 31, 2020
Asset Derivatives Liability Derivatives
Type of Risk Exposure Location on Statement of Assets and Liabilities Value Location on Statement of Assets and Liabilities Value
Foreign Currency Risk Unrealized appreciation on forward foreign currency exchange contracts $ 906,972  Unrealized depreciation on forward foreign currency exchange contracts $ 162,867 

Effect of Derivative Instruments on the Statement of Operations for the Year Ended October 31, 2020
Net Realized Gain (Loss) Change in Net Unrealized Appreciation (Depreciation)
Type of Risk Exposure Location on Statement of Operations Value Location on Statement of Operations Value
Equity Price Risk Net realized gain (loss) on futures contract transactions $ 11,298,722  Change in net unrealized appreciation (depreciation) on futures contracts $ (1,432,221)
Foreign Currency Risk Net realized gain (loss) on forward foreign currency exchange contract transactions (5,567,078) Change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts 1,123,274 
$ 5,731,644  $ (308,947)

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

9. Federal Tax Information

On December 8, 2020, the fund declared and paid a per-share distribution from net realized gains to shareholders of record on December 7, 2020 of $1.5632 for the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 24,642,374  $ 83,919,008 
Long-term capital gains $ 630,884,508  $ 751,261,055 
23



The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 5,119,257,182 
Gross tax appreciation of investments $ 5,282,269,176 
Gross tax depreciation of investments (87,425,310)
Net tax appreciation (depreciation) of investments 5,194,843,866 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 21,584 
Net tax appreciation (depreciation) $ 5,194,865,450 
Undistributed ordinary income — 
Accumulated long-term gains $ 376,496,713 
Late-year ordinary loss deferral $ (5,155,258)
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.

Loss deferrals represent certain qualified losses that the fund has elected to treat as having been incurred in the following fiscal year for federal income tax purposes.

10. Reorganization

On September 11, 2019, the Board of Directors approved an agreement and plan of reorganization (the reorganization), whereby the net assets of All Cap Growth Fund, one fund in a series issued by the corporation, were transferred to Growth Fund in exchange for shares of Growth Fund. The purpose of the transaction was to combine two funds with substantially similar investment objectives and strategies. The financial statements and performance history of Growth Fund survived after the reorganization. The reorganization was effective at the close of the NYSE on February 21, 2020.

The reorganization was accomplished by a tax-free exchange of shares. On February 21, 2020, All Cap Growth Fund exchanged its shares for shares of Growth Fund as follows:
Original Fund/Class
Shares Exchanged
New Fund/Class
Shares Received
All Cap Growth Fund – Investor Class 36,344,493 Growth Fund – Investor Class 33,740,937
All Cap Growth Fund – I Class 256,052 Growth Fund – I Class 238,480
All Cap Growth Fund – A Class 451,934 Growth Fund – A Class 422,151
All Cap Growth Fund – C Class 137,457 Growth Fund – C Class 124,022
All Cap Growth Fund – R Class 495,557 Growth Fund – R Class 461,820

The net assets of All Cap Growth Fund and Growth Fund immediately before the reorganization were $1,326,350,211 and $8,778,658,792, respectively. All Cap Growth Fund's unrealized appreciation of $530,451,716 was combined with that of Growth Fund. Immediately after the reorganization, the combined net assets were $10,105,009,003.

Assuming the reorganization had been completed on November 1, 2019, the beginning of the annual reporting period, the pro forma results of operations for the period ended October 31, 2020 are as follows:
Net investment income (loss) $ 1,186,943 
Net realized and unrealized gain (loss) 2,308,332,754 
Net increase (decrease) in net assets resulting from operations $ 2,309,519,697 

Because the combined investment portfolios have been managed as a single integrated portfolio since the reorganization was completed, it is not practicable to separate the amounts of revenue and earnings of All Cap Growth Fund that have been included in the fund’s Statement of Operations since February 21, 2020.
24



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $35.80 (0.02) 9.12 9.10 (0.15) (2.81) (2.96) $41.94 26.70% 0.97% (0.04)% 33% $7,656,430 
2019 $34.94 0.08 4.70 4.78 (0.08) (3.84) (3.92) $35.80 16.35% 0.98% 0.24% 30% $5,937,959 
2018 $34.93 0.04 3.35 3.39 (0.06) (3.32) (3.38) $34.94 10.22% 0.97% 0.13% 38% $5,627,171 
2017 $28.64 0.08 7.67 7.75 (0.17) (1.29) (1.46) $34.93 28.26% 0.98% 0.26% 48% $5,648,965 
2016 $30.57 0.16 (0.08) 0.08 (0.10) (1.91) (2.01) $28.64 0.40% 0.98% 0.57% 36% $5,122,550 
I Class
2020 $36.56 0.06 9.29 9.35 (0.23) (2.81) (3.04) $42.87 26.93% 0.77% 0.16% 33% $1,719,814 
2019 $35.59 0.15 4.81 4.96 (0.15) (3.84) (3.99) $36.56 16.62% 0.78% 0.44% 30% $1,382,618 
2018 $35.52 0.12 3.40 3.52 (0.13) (3.32) (3.45) $35.59 10.46% 0.77% 0.33% 38% $1,230,065 
2017 $29.11 0.15 7.78 7.93 (0.23) (1.29) (1.52) $35.52 28.48% 0.78% 0.46% 48% $1,271,821 
2016 $31.03 0.23 (0.08) 0.15 (0.16) (1.91) (2.07) $29.11 0.64% 0.78% 0.77% 36% $1,297,685 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Y Class
2020 $36.61 0.13 9.30 9.43 (0.30) (2.81) (3.11) $42.93 27.15% 0.62% 0.31% 33% $52,046 
2019 $35.64 0.20 4.81 5.01 (0.20) (3.84) (4.04) $36.61 16.78% 0.63% 0.59% 30% $53,641 
2018 $35.54 0.17 3.40 3.57 (0.15) (3.32) (3.47) $35.64 10.61% 0.62% 0.48% 38% $52,601 
2017(3)
$30.93 0.08 4.53 4.61 $35.54 14.90%
0.63%(4)
0.43%(4)
48%(5)
$56,218 
A Class
2020 $34.52 (0.10) 8.75 8.65 (0.04) (2.81) (2.85) $40.32 26.38% 1.22% (0.29)% 33% $102,472 
2019 $33.82
(6)
4.54 4.54 (3.84) (3.84) $34.52 16.06% 1.23% (0.01)% 30% $93,422 
2018 $33.94 (0.04) 3.24 3.20 (3.32) (3.32) $33.82 9.94% 1.22% (0.12)% 38% $103,115 
2017 $27.86 0.01 7.46 7.47 (0.10) (1.29) (1.39) $33.94 27.95% 1.23% 0.01% 48% $113,348 
2016 $29.78 0.10 (0.08) 0.02 (0.03) (1.91) (1.94) $27.86 0.18% 1.23% 0.32% 36% $147,133 
C Class
2020 $32.37 (0.37) 8.18 7.81 (2.81) (2.81) $37.37 25.43% 1.97% (1.04)% 33% $13,527 
2019 $32.18 (0.23) 4.26 4.03 (3.84) (3.84) $32.37 15.23% 1.98% (0.76)% 30% $8,408 
2018 $32.67 (0.29) 3.12 2.83 (3.32) (3.32) $32.18 9.12% 1.97% (0.87)% 38% $9,871 
2017 $26.97 (0.21) 7.20 6.99 (1.29) (1.29) $32.67 26.99% 1.98% (0.74)% 48% $9,962 
2016 $29.08 (0.11) (0.09) (0.20) (1.91) (1.91) $26.97 (0.58)% 1.98% (0.43)% 36% $9,379 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R Class
2020 $33.50 (0.19) 8.49 8.30 (0.03) (2.81) (2.84) $38.96 26.07% 1.47% (0.54)% 33% $96,170 
2019 $33.02 (0.08) 4.40 4.32 (3.84) (3.84) $33.50 15.78% 1.48% (0.26)% 30% $87,302 
2018 $33.29 (0.13) 3.18 3.05 (3.32) (3.32) $33.02 9.66% 1.47% (0.37)% 38% $100,915 
2017 $27.35 (0.07) 7.32 7.25 (0.02) (1.29) (1.31) $33.29 27.62% 1.48% (0.24)% 48% $104,368 
2016 $29.31 0.02 (0.07) (0.05) (1.91) (1.91) $27.35 (0.06)% 1.48% 0.07% 36% $96,415 
R5 Class
2020 $36.59 0.08 9.28 9.36 (0.23) (2.81) (3.04) $42.91 26.94% 0.77% 0.16% 33% $433 
2019 $35.62 0.15 4.81 4.96 (0.15) (3.84) (3.99) $36.59 16.61% 0.78% 0.44% 30% $533 
2018 $35.53 0.12 3.40 3.52 (0.11) (3.32) (3.43) $35.62 10.45% 0.77% 0.33% 38% $404 
2017(3)
$30.95 0.05 4.53 4.58 $35.53 14.80%
0.78%(4)
0.27%(4)
48%(5)
$6 
R6 Class
2020 $36.56 0.12 9.29 9.41 (0.30) (2.81) (3.11) $42.86 27.13% 0.62% 0.31% 33% $611,600 
2019 $35.59 0.21 4.80 5.01 (0.20) (3.84) (4.04) $36.56 16.81% 0.63% 0.59% 30% $479,123 
2018 $35.53 0.17 3.40 3.57 (0.19) (3.32) (3.51) $35.59 10.60% 0.62% 0.48% 38% $834,003 
2017 $29.11 0.18 7.80 7.98 (0.27) (1.29) (1.56) $35.53 28.71% 0.63% 0.61% 48% $963,039 
2016 $31.04 0.26 (0.07) 0.19 (0.21) (1.91) (2.12) $29.11 0.76% 0.63% 0.92% 36% $390,201 




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)April 10, 2017 (commencement of sale) through October 31, 2017.
(4)Annualized.
(5)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.
(6)Per-share amount was less than $0.005.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Growth Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Growth Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.

29



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
30



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
31



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





32



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
33



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-, three-, and five-year periods and below its benchmark for the ten-year period reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
34



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was above the median of the total expense ratios of the Fund’s peer expense universe
35



and was within the range of its peer expense group. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
36



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



37



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $24,642,374, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $641,420,862, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $10,536,354 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).
38



Notes

39



Notes























































40








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
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Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90970 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Heritage Fund
Investor Class (TWHIX)
I Class (ATHIX)
Y Class (ATHYX)
A Class (ATHAX)
C Class (AHGCX)
R Class (ATHWX)
R5 Class (ATHGX)
R6 Class (ATHDX)
















Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
 
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
14
Statement of Operations
15
Statement of Changes in Net Assets
16
Notes to Financial Statements
17
Financial Highlights
24
Report of Independent Registered Public Accounting Firm
28
Management
29
Approval of Management Agreement
32
Additional Information
36

















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
Total Returns as of October 31, 2020
    Average Annual Returns
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class TWHIX 25.00% 13.12% 12.50% 11/10/87
Russell Midcap Growth Index 21.14% 14.14% 14.11%
I Class ATHIX 25.25% 13.35% 12.73% 6/16/97
Y Class ATHYX 25.43% 17.02% 4/10/17
A Class ATHAX 7/11/97
No sales charge 24.73% 12.84% 12.23%
With sales charge 17.53% 11.51% 11.57%
C Class AHGCX 23.73% 11.99% 11.38% 6/26/01
R Class ATHWX 24.37% 12.56% 11.95% 9/28/07
R5 Class ATHGX 25.25% 16.84% 4/10/17
R6 Class ATHDX 25.43% 13.52% 12.59% 7/26/13
Average annual returns since inception are presented when ten years of performance history is not available.

Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.




















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-59EB2326B4984B9B8C61.JPG
Value on October 31, 2020
Investor Class — $32,514
Russell Midcap Growth Index — $37,485
Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class
1.01% 0.81% 0.66% 1.26% 2.01% 1.51% 0.81% 0.66%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.







Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary

Portfolio Managers: Rob Brookby and Nalin Yogasundram

Performance Summary

Heritage returned 25.00%* for the 12 months ended October 31, 2020, outpacing the 21.14% return of the fund’s benchmark, the Russell Midcap Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell Midcap Growth Index, health care and information technology were the top-performing sectors. Energy posted a significant loss as oversupply and declining oil prices weighed on the sector.

The information technology and health care sectors led outperformance relative to the benchmark, due primarily to stock selection. Stock decisions in the communication services and consumer discretionary sectors detracted.

Information Technology Led Performance

Stock selection among IT services companies led performance in the information technology sector, which was far and away the fund’s top-performing sector relative to the benchmark. Square was a significant contributor. The payments company outperformed as its main businesses—small retailers and peer to peer—both benefited from the stay-at-home restrictions. Coffee shops and restaurants have had to adjust to new business models, and individuals are increasingly using digital payments. We see these as secular trends that have been accelerated by the pandemic. Twilio was another top contributor. The company’s software allows developers to create apps that communicate with one another. In addition to its apps that support travel industries, its software enables apps that allow videoconferencing between doctors and patients, which has taken hold during the pandemic’s stay-at-home mandates.

Advanced Micro Devices aided performance. The chipmaker beat earnings expectations as it benefited from increased semiconductor demand for gaming as well as missteps by its large competitor Intel. Another top contributor, RingCentral, helps companies move their telecommunications into the cloud, providing features such as voice, video, data and call forwarding of business calls to mobile phones. We think the company has a long-term tailwind but was also seen as a beneficiary of the work-from-home environment during the pandemic.

Other significant contributors included Immunomedics, whose stock price climbed following Gilead Sciences’ announcement that it would acquire the maker of cancer drugs. As a result of the deal, Immunomedics was eliminated. Peloton Interactive, a leader in home fitness, benefited from the stay-at-home environment created by COVID-19. We think the trend will continue after the pandemic, and Peloton is expanding its offerings into lower-priced treadmills and bikes.

Communication Services Stocks Detracted

Stock selection among entertainment and interactive media and services companies weighed on relative performance. Companies such as Live Nation Entertainment fell as the pandemic curtailed live events. We eliminated our holding. We eliminated Pinterest during the fourth quarter of 2019



*All fund returns referenced in this commentary are for Investor Class shares. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.
5



and so were underweight the social media stock relative to the benchmark over the course of the fiscal year. This hampered performance as Pinterest posted strong earnings and user growth.

Underweighting internet and direct marketing retail stocks hurt performance in the consumer discretionary sector as stay-at-home mandates gave a boost to the industry. Stock choices among distributors also detracted. LKQ, a provider of aftermarket automobile parts, declined as shelter-in-place restrictions in the U.S. and Europe caused people to drive fewer miles. We think this is a near-term issue and that, as restrictions are lifted, miles driven will increase, aided by low gasoline prices and ongoing weakness in air travel.

Other significant detractors included DocuSign, which was underweight relative to the benchmark. The cloud-based electronic signature company outperformed as it benefited from increased demand for its services because of social distancing mandates. Another detractor was Japan-based Shiseido, a skin care and cosmetics maker that primarily sells in duty-free shops in China and Japan. The pandemic hurt the travel industry, but we saw a pickup in China and took the opportunity to add to our position. SelectQuote, an online direct-to-consumer insurance broker, has exposure to life insurance, home and automobile insurance, and senior health insurance through Medicare Advantage. The stock lagged on concerns about profitability under competitive pressures as Walmart enters the field.

Outlook

Our process uses a combined top-down, bottom-up fundamental framework aimed at identifying mid-cap companies producing attractive, sustainable growth. We seek to reduce unintended, nonfundamental risks and align the portfolio with fundamental, company-specific risks that we believe will be rewarded over time. As a result of this approach, our sector and industry allocations reflect where we are finding opportunities at a given time.

Consumer discretionary ended the period as the portfolio’s largest overweight relative to the benchmark. Communication services ended as the largest underweight sector.
























6



Fund Characteristics 
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Cadence Design Systems, Inc. 3.1%
Xilinx, Inc. 2.6%
Cognex Corp. 2.4%
Twilio, Inc., Class A 2.2%
Veeva Systems, Inc., Class A 2.2%
Splunk, Inc. 2.1%
Align Technology, Inc. 2.1%
Skyworks Solutions, Inc. 2.0%
Square, Inc., Class A 2.0%
Teleflex, Inc. 1.9%
Top Five Industries % of net assets
Software 16.5%
Semiconductors and Semiconductor Equipment 8.4%
Health Care Equipment and Supplies 7.5%
IT Services 4.2%
Electronic Equipment, Instruments and Components 4.2%
Types of Investments in Portfolio % of net assets
Common Stocks 99.6%
Temporary Cash Investments 0.5%
Temporary Cash Investments - Securities Lending Collateral 0.3%
Other Assets and Liabilities (0.4)%

7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

8




Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
Investor Class $1,000 $1,275.10 $5.72 1.00%
I Class $1,000 $1,276.80 $4.58 0.80%
Y Class $1,000 $1,277.70 $3.72 0.65%
A Class $1,000 $1,274.00 $7.15 1.25%
C Class $1,000 $1,269.40 $11.41 2.00%
R Class $1,000 $1,272.60 $8.57 1.50%
R5 Class $1,000 $1,276.80 $4.58 0.80%
R6 Class $1,000 $1,277.70 $3.72 0.65%
Hypothetical
Investor Class $1,000 $1,020.11 $5.08 1.00%
I Class $1,000 $1,021.12 $4.06 0.80%
Y Class $1,000 $1,021.87 $3.30 0.65%
A Class $1,000 $1,018.85 $6.34 1.25%
C Class $1,000 $1,015.08 $10.13 2.00%
R Class $1,000 $1,017.60 $7.61 1.50%
R5 Class $1,000 $1,021.12 $4.06 0.80%
R6 Class $1,000 $1,021.87 $3.30 0.65%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 99.6%
Auto Components — 1.1%
Aptiv plc 548,341  $ 52,909,423 
Beverages — 1.3%
Boston Beer Co., Inc. (The), Class A(1)
64,024  66,532,460 
Biotechnology — 3.8%
ACADIA Pharmaceuticals, Inc.(1)
742,131  34,471,985 
Alnylam Pharmaceuticals, Inc.(1)
386,684  47,550,532 
Argenx SE, ADR(1)
135,792  33,694,069 
Seagen, Inc.(1)
274,497  45,786,100 
Turning Point Therapeutics, Inc.(1)
297,013  27,381,628 
188,884,314 
Building Products — 2.9%
Fortune Brands Home & Security, Inc. 886,939  71,726,757 
Trane Technologies plc 532,039  70,628,177 
142,354,934 
Capital Markets — 3.8%
LPL Financial Holdings, Inc. 646,613  51,683,777 
MarketAxess Holdings, Inc. 112,440  60,588,294 
MSCI, Inc. 213,928  74,840,572 
187,112,643 
Chemicals — 0.5%
Albemarle Corp. 261,001  24,327,903 
Communications Equipment — 2.2%
Arista Networks, Inc.(1)
206,219  43,079,149 
F5 Networks, Inc.(1)
508,345  67,579,384 
110,658,533 
Containers and Packaging — 3.0%
Avery Dennison Corp. 508,086  70,314,022 
Ball Corp. 888,881  79,110,409 
149,424,431 
Distributors — 0.8%
LKQ Corp.(1)
1,249,055  39,957,269 
Diversified Consumer Services — 0.3%
Chegg, Inc.(1)
177,955  13,069,015 
Electrical Equipment — 4.1%
AMETEK, Inc. 705,961  69,325,370 
Generac Holdings, Inc.(1)
100,382  21,095,277 
nVent Electric plc 1,945,529  35,116,799 
Rockwell Automation, Inc. 145,260  34,444,051 
Sensata Technologies Holding plc(1)
1,026,930  44,887,111 
204,868,608 
Electronic Equipment, Instruments and Components — 4.2%
Cognex Corp. 1,843,079  121,458,906 
Keysight Technologies, Inc.(1)
842,690  88,372,900 
209,831,806 
Entertainment — 2.4%
Roku, Inc.(1)
302,956  61,318,294 
10



Shares Value
Zynga, Inc., Class A(1)
6,679,904  $ 60,052,337 
121,370,631 
Health Care Equipment and Supplies — 7.5%
Align Technology, Inc.(1)
241,133  102,741,949 
DexCom, Inc.(1)
123,252  39,388,874 
IDEXX Laboratories, Inc.(1)
149,685  63,589,182 
Masimo Corp.(1)
319,593  71,531,305 
Teleflex, Inc. 296,019  94,202,126 
371,453,436 
Health Care Providers and Services — 3.2%
Amedisys, Inc.(1)
286,804  74,282,236 
Encompass Health Corp. 1,350,345  82,789,652 
157,071,888 
Health Care Technology — 3.1%
Teladoc Health, Inc.(1)(2)
229,093  45,007,611 
Veeva Systems, Inc., Class A(1)
410,086  110,743,724 
155,751,335 
Hotels, Restaurants and Leisure — 3.0%
Chipotle Mexican Grill, Inc.(1)
78,032  93,753,887 
Las Vegas Sands Corp. 1,144,443  55,001,931 
148,755,818 
Household Durables — 1.2%
D.R. Horton, Inc. 919,446  61,428,187 
Insurance — 0.7%
SelectQuote, Inc.(1)
1,961,668  33,779,923 
Interactive Media and Services — 1.6%
Match Group, Inc.(1)
678,858  79,277,037 
Internet and Direct Marketing Retail — 1.4%
Chewy, Inc., Class A(1)
570,725  35,156,660 
Wayfair, Inc., Class A(1)
138,916  34,455,336 
69,611,996 
IT Services — 4.2%
Square, Inc., Class A(1)
638,062  98,823,043 
Twilio, Inc., Class A(1)
399,749  111,517,978 
210,341,021 
Leisure Products — 1.0%
Peloton Interactive, Inc., Class A(1)
440,119  48,505,515 
Life Sciences Tools and Services — 2.7%
Mettler-Toledo International, Inc.(1)
93,371  93,175,855 
Repligen Corp.(1)
244,420  40,713,039 
133,888,894 
Machinery — 2.7%
Graco, Inc. 938,634  58,101,445 
Parker-Hannifin Corp. 361,056  75,229,628 
133,331,073 
Personal Products — 1.3%
Shiseido Co. Ltd. 1,065,300  65,946,706 
Pharmaceuticals — 1.9%
Horizon Therapeutics plc(1)
756,248  56,665,663 
Jazz Pharmaceuticals plc(1)
244,220  35,192,102 
91,857,765 
Professional Services — 2.3%
CoStar Group, Inc.(1)
54,579  44,951,810 
11



Shares Value
Verisk Analytics, Inc. 391,958  $ 69,756,765 
114,708,575 
Road and Rail — 0.8%
J.B. Hunt Transport Services, Inc. 343,656  41,836,681 
Semiconductors and Semiconductor Equipment — 8.4%
Advanced Micro Devices, Inc.(1)
558,036  42,014,531 
Marvell Technology Group Ltd. 1,886,045  70,745,548 
Skyworks Solutions, Inc. 701,744  99,149,410 
Teradyne, Inc. 829,780  72,896,173 
Xilinx, Inc. 1,089,902  129,360,468 
414,166,130 
Software — 16.5%
Atlassian Corp. plc, Class A(1)
218,384  41,846,742 
Cadence Design Systems, Inc.(1)
1,398,765  152,982,928 
Coupa Software, Inc.(1)
174,866  46,811,628 
DocuSign, Inc.(1)
325,299  65,791,723 
Envestnet, Inc.(1)
543,914  41,739,960 
HubSpot, Inc.(1)
255,058  73,984,674 
Manhattan Associates, Inc.(1)
951,904  81,387,792 
Palo Alto Networks, Inc.(1)
365,626  80,872,815 
RingCentral, Inc., Class A(1)
255,188  65,925,268 
Slack Technologies, Inc., Class A(1)
2,388,917  61,108,497 
Splunk, Inc.(1)
526,759  104,319,353 
816,771,380 
Specialty Retail — 3.4%
Burlington Stores, Inc.(1)
360,250  69,737,195 
Five Below, Inc.(1)
352,465  46,997,683 
Lithia Motors, Inc., Class A 218,921  50,257,694 
166,992,572 
Textiles, Apparel and Luxury Goods — 1.5%
lululemon athletica, Inc.(1)
236,456  75,498,036 
Trading Companies and Distributors — 0.8%
W.W. Grainger, Inc. 112,546  39,393,351 
TOTAL COMMON STOCKS
(Cost $3,805,959,166)
4,941,669,289 
TEMPORARY CASH INVESTMENTS — 0.5%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $9,737,759), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $9,580,536) 9,580,488 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 0.125%, 7/15/30, valued at $17,029,928), at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $16,696,083) 16,696,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 708  708 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $26,277,196)
26,277,196 
TEMPORARY CASH INVESTMENTS - SECURITIES LENDING COLLATERAL(3) — 0.3%
State Street Navigator Securities Lending Government Money Market Portfolio
(Cost $12,856,261)
12,856,261  12,856,261 
TOTAL INVESTMENT SECURITIES — 100.4%
(Cost $3,845,092,623)
4,980,802,746 
OTHER ASSETS AND LIABILITIES — (0.4)% (20,296,017)
TOTAL NET ASSETS — 100.0% $ 4,960,506,729 
12



FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
JPY 164,908,440 USD 1,565,107 Bank of America N.A. 12/30/20 $ 11,401 
JPY 304,888,860 USD 2,917,471 Bank of America N.A. 12/30/20 (2,765)
USD 57,473,652 JPY 6,029,704,530 Bank of America N.A. 12/30/20 (169,698)
USD 2,724,057 JPY 287,631,000 Bank of America N.A. 12/30/20 (25,665)
USD 1,334,084 JPY 140,939,190 Bank of America N.A. 12/30/20 (13,280)
USD 1,441,220 JPY 151,485,660 Bank of America N.A. 12/30/20 (6,967)
USD 2,172,886 JPY 227,228,490 Bank of America N.A. 12/30/20 605 
$ (206,369)

NOTES TO SCHEDULE OF INVESTMENTS
ADR - American Depositary Receipt
JPY - Japanese Yen
USD - United States Dollar
(1)Non-income producing.
(2)Security, or a portion thereof, is on loan. At the period end, the aggregate value of securities on loan was $12,597,212. The amount of securities on loan indicated may not correspond with the securities on loan identified because securities with pending sales are in the process of recall from the brokers.
(3)Investment of cash collateral from securities on loan. At the period end, the aggregate value of the collateral held by the fund was $12,856,261.


See Notes to Financial Statements.
13



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $3,832,236,362) — including $12,597,212 of securities on loan $ 4,967,946,485 
Investment made with cash collateral received for securities on loan, at value
(cost of $12,856,261)
12,856,261 
Total investment securities, at value (cost of $3,845,092,623) 4,980,802,746 
Receivable for investments sold 4,707,368 
Receivable for capital shares sold 1,315,062 
Unrealized appreciation on forward foreign currency exchange contracts 12,006 
Dividends and interest receivable 511,977 
Securities lending receivable 7,515 
4,987,356,674 
Liabilities
Payable for collateral received for securities on loan 12,856,261 
Payable for investments purchased 4,839,017 
Payable for capital shares redeemed 4,542,372 
Unrealized depreciation on forward foreign currency exchange contracts 218,375 
Accrued management fees 4,288,730 
Distribution and service fees payable 105,190 
26,849,945 
Net Assets $ 4,960,506,729 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 3,137,672,875 
Distributable earnings 1,822,833,854 
$ 4,960,506,729 

Net Assets Shares Outstanding Net Asset Value Per Share
Investor Class, $0.01 Par Value $4,083,843,478 167,487,419 $24.38
I Class, $0.01 Par Value $328,635,896 12,328,954 $26.66
Y Class, $0.01 Par Value $52,977,545 1,955,084 $27.10
A Class, $0.01 Par Value $281,636,680 12,998,064 $21.67*
C Class, $0.01 Par Value $31,676,544 2,081,092 $15.22
R Class, $0.01 Par Value $31,861,687 1,477,151 $21.57
R5 Class, $0.01 Par Value $1,338,561 50,213 $26.66
R6 Class, $0.01 Par Value $148,536,338 5,481,633 $27.10
*Maximum offering price $22.99 (net asset value divided by 0.9425).


See Notes to Financial Statements.

14



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $28,307) $ 24,023,423 
Interest 287,447 
Securities lending, net 32,927 
24,343,797 
Expenses:
Management fees 44,748,645 
Distribution and service fees:
A Class 660,263 
C Class 345,144 
R Class 159,983 
Directors' fees and expenses 148,549 
Other expenses 3,458 
46,066,042 
Net investment income (loss) (21,722,245)
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 743,725,789 
Forward foreign currency exchange contract transactions (1,057,145)
Foreign currency translation transactions (22,007)
742,646,637 
Change in net unrealized appreciation (depreciation) on:
Investments 310,240,150 
Forward foreign currency exchange contracts (302,500)
Translation of assets and liabilities in foreign currencies 194 
309,937,844 
Net realized and unrealized gain (loss) 1,052,584,481 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 1,030,862,236 


See Notes to Financial Statements.

15



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets
October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ (21,722,245) $ (17,330,407)
Net realized gain (loss) 742,646,637  519,001,944 
Change in net unrealized appreciation (depreciation) 309,937,844  196,321,808 
Net increase (decrease) in net assets resulting from operations 1,030,862,236  697,993,345 
Distributions to Shareholders
From earnings:
Investor Class (393,425,552) (679,904,197)
I Class (30,338,935) (41,064,427)
Y Class (5,616,329) (1,986,316)
A Class (31,178,565) (53,942,496)
C Class (6,010,954) (13,662,155)
R Class (3,890,228) (6,464,936)
R5 Class (409,601) (529,611)
R6 Class (13,008,625) (22,767,081)
Decrease in net assets from distributions (483,878,789) (820,321,219)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) (129,879,890) 119,035,175 
Net increase (decrease) in net assets 417,103,557  (3,292,699)
Net Assets
Beginning of period 4,543,403,172  4,546,695,871 
End of period $ 4,960,506,729  $ 4,543,403,172 


See Notes to Financial Statements.

16



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Heritage Fund (the fund) is one fund in a series issued by the corporation. The fund's investment objective is to seek long-term capital growth.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge.
2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.
Fixed income securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. U.S. Treasury and Government Agency securities are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information.
Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.


17



If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.

The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

18



Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.

Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.
Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming
shareholder, which represents the pro rata share of undistributed net investment income and net realized
gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.
Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

The following table reflects a breakdown of transactions accounted for as secured borrowings, the gross obligation by the type of collateral pledged, and the remaining contractual maturity of those transactions as of October 31, 2020.
Remaining Contractual Maturity of Agreements
Overnight and
Continuous
<30 days
Between
30 & 90 days
>90 days
Total
Securities Lending Transactions(1)
Common Stocks $ 12,856,261  —  —  —  $ 12,856,261 
Gross amount of recognized liabilities for securities lending transactions $ 12,856,261 

(1)Amount represents the payable for cash collateral received for securities on loan. This will generally be in the Overnight and Continuous column as the securities are typically callable on demand.


19



3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. Various funds issued by American Century Asset Allocation Portfolios, Inc. own, in aggregate, 5% of the shares of the fund.
Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class.

The annual management fee for each class is as follows:
Investor Class
I
Class
Y
Class
A
 Class
C
 Class
R
Class
R5 Class
R6 Class
1.000% 0.800% 0.650% 1.000% 1.000% 1.000% 0.800% 0.650%

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.

Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.

Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $942,759 and $10,534,618, respectively. The effect of interfund transactions on the Statement of Operations was $8,033,372 in net realized gain (loss) on investment transactions.
4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments, for the period ended October 31, 2020 were $3,847,869,301 and $4,431,315,317, respectively.

20



5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019
Shares Amount Shares Amount
Investor Class/Shares Authorized 2,100,000,000  2,100,000,000 
Sold 8,318,301  $ 170,505,402  8,881,792  $ 183,562,881 
Issued in reinvestment of distributions 18,572,102  380,170,938  38,287,328  660,456,399 
Redeemed (29,696,397) (623,476,372) (40,207,691) (832,873,931)
(2,805,994) (72,800,032) 6,961,429  11,145,349 
I Class/Shares Authorized 175,000,000  175,000,000 
Sold 3,026,131  72,188,642  8,282,472  187,142,858 
Issued in reinvestment of distributions 1,292,245  28,868,755  2,030,579  37,809,381 
Redeemed (6,286,808) (144,634,896) (6,042,339) (132,802,177)
(1,968,432) (43,577,499) 4,270,712  92,150,062 
Y Class/Shares Authorized 30,000,000  30,000,000 
Sold 2,100,087  50,592,554  879,608  20,066,401 
Issued in reinvestment of distributions 242,850  5,507,845  88,190  1,662,380 
Redeemed (1,637,996) (41,380,807) (106,938) (2,450,380)
704,941  14,719,592  860,860  19,278,401 
A Class/Shares Authorized 170,000,000  170,000,000 
Sold 2,133,477  40,359,264  2,764,436  52,092,399 
Issued in reinvestment of distributions 1,643,351  29,958,297  3,291,370  51,312,456 
Redeemed (4,216,962) (78,996,914) (5,543,255) (103,070,801)
(440,134) (8,679,353) 512,551  334,054 
C Class/Shares Authorized 70,000,000  70,000,000 
Sold 102,610  1,363,953  219,280  2,780,542 
Issued in reinvestment of distributions 435,672  5,615,807  1,097,917  12,768,775 
Redeemed (1,194,272) (16,177,174) (1,930,896) (27,011,815)
(655,990) (9,197,414) (613,699) (11,462,498)
R Class/Shares Authorized 40,000,000  40,000,000 
Sold 308,951  5,835,185  346,118  6,576,154 
Issued in reinvestment of distributions 212,437  3,864,234  408,317  6,369,746 
Redeemed (719,551) (13,655,328) (594,071) (11,067,893)
(198,163) (3,955,909) 160,364  1,878,007 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold 45,219  1,091,389  21,011  467,950 
Issued in reinvestment of distributions 18,335  409,601  28,443  529,611 
Redeemed (169,115) (3,123,113) (17,479) (385,887)
(105,561) (1,622,123) 31,975  611,674 
R6 Class/Shares Authorized 70,000,000  70,000,000 
Sold 1,630,358  37,972,288  1,574,058  35,568,182 
Issued in reinvestment of distributions 573,408  13,004,903  1,207,802  22,767,071 
Redeemed (2,378,050) (55,744,343) (2,453,088) (53,235,127)
(174,284) (4,767,152) 328,772  5,100,126 
Net increase (decrease) (5,643,617) $ (129,879,890) 12,512,964  $ 119,035,175 
21



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 4,875,722,583  $ 65,946,706  — 
Temporary Cash Investments 708  26,276,488  — 
Temporary Cash Investments - Securities Lending Collateral 12,856,261  —  — 
$ 4,888,579,552  $ 92,223,194  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 12,006  — 
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 218,375  — 

7. Derivative Instruments

Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $52,182,270.
22



The value of foreign currency risk derivative instruments as of October 31, 2020, is disclosed on the Statement of Assets and Liabilities as an asset of $12,006 in unrealized appreciation on forward foreign currency exchange contracts and a liability of $218,375 in unrealized depreciation on forward foreign currency exchange contracts. For the year ended October 31, 2020, the effect of foreign currency risk derivative instruments on the Statement of Operations was $(1,057,145) in net realized gain (loss) on forward foreign currency exchange contract transactions and $(302,500) in change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts.
8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.
The fund invests in common stocks of small companies. Because of this, the fund may be subject to greater risk and market fluctuations than a fund investing in larger, more established companies.

9. Federal Tax Information

On December 8, 2020, the fund declared and paid a per-share distribution from net realized gains to
shareholders of record on December 7, 2020 of $3.5469 for the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class.

The tax character of distributions paid during the years ended October 31,2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income —  $ 83,304,333 
Long-term capital gains $ 483,878,789  $ 737,016,886 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 3,849,935,204 
Gross tax appreciation of investments $ 1,250,442,580 
Gross tax depreciation of investments (119,575,038)
Net tax appreciation (depreciation) of investments 1,130,867,542 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 194 
Net tax appreciation (depreciation) $ 1,130,867,736 
Undistributed ordinary income — 
Accumulated long-term gains $ 714,811,654 
Late-year ordinary loss deferral $ (22,845,536)
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.

Loss deferrals represent certain qualified losses that the fund has elected to treat as having been incurred in the following fiscal year for federal income tax purposes.
23



Financial Highlights
 
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net
Realized
Gains
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $21.74 (0.10) 5.09 4.99 (2.35) $24.38 25.00% 1.00% (0.47)% 85% $4,083,843 
2019 $23.19 (0.08) 2.95 2.87 (4.32) $21.74 17.22% 1.00% (0.38)% 82% $3,702,699 
2018 $23.67 (0.07) 1.70 1.63 (2.11) $23.19 7.16% 1.00% (0.30)% 85% $3,787,202 
2017 $21.28 (0.03) 4.18 4.15 (1.76) $23.67 20.77% 1.01% (0.15)% 56% $4,083,669 
2016 $24.59 (0.05) (0.53) (0.58) (2.73) $21.28 (2.26)% 1.00% (0.21)% 62% $3,823,112 
I Class
2020 $23.52 (0.06) 5.55 5.49 (2.35) $26.66 25.25% 0.80% (0.27)% 85% $328,636 
2019 $24.66 (0.04) 3.22 3.18 (4.32) $23.52 17.50% 0.80% (0.18)% 82% $336,242 
2018 $25.00 (0.03) 1.80 1.77 (2.11) $24.66 7.35% 0.80% (0.10)% 85% $247,267 
2017 $22.34
(3)
4.42 4.42 (1.76) $25.00 21.01% 0.81% 0.05% 56% $262,095 
2016 $25.62
(3)
(0.55) (0.55) (2.73) $22.34 (2.07)% 0.80% (0.01)% 62% $155,695 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net
Realized
Gains
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Y Class
2020 $23.84 (0.03) 5.64 5.61 (2.35) $27.10 25.43% 0.65% (0.12)% 85% $52,978 
2019 $24.90 (0.01) 3.27 3.26 (4.32) $23.84 17.68% 0.65% (0.03)% 82% $29,803 
2018 $25.19
(3)
1.82 1.82 (2.11) $24.90 7.51% 0.65% 0.05% 85% $9,694 
2017(4)
$22.84 0.02 2.33 2.35 $25.19 10.29%
0.66%(5)
0.12%(5)
56%(6)
$6 
A Class
2020 $19.61 (0.14) 4.55 4.41 (2.35) $21.67 24.73% 1.25% (0.72)% 85% $281,637 
2019 $21.42 (0.12) 2.63 2.51 (4.32) $19.61 16.91% 1.25% (0.63)% 82% $263,578 
2018 $22.07 (0.12) 1.58 1.46 (2.11) $21.42 6.89% 1.25% (0.55)% 85% $276,813 
2017 $20.00 (0.08) 3.91 3.83 (1.76) $22.07 20.48% 1.26% (0.40)% 56% $353,039 
2016 $23.33 (0.09) (0.51) (0.60) (2.73) $20.00 (2.53)% 1.25% (0.46)% 62% $570,298 
C Class
2020 $14.54 (0.20) 3.23 3.03 (2.35) $15.22 23.73% 2.00% (1.47)% 85% $31,677 
2019 $17.18 (0.19) 1.87 1.68 (4.32) $14.54 16.06% 2.00% (1.38)% 82% $39,794 
2018 $18.22 (0.23) 1.30 1.07 (2.11) $17.18 6.13% 2.00% (1.30)% 85% $57,552 
2017 $16.92 (0.19) 3.25 3.06 (1.76) $18.22 19.58% 2.01% (1.15)% 56% $88,629 
2016 $20.31 (0.21) (0.45) (0.66) (2.73) $16.92 (3.29)% 2.00% (1.21)% 62% $103,292 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net
Realized
Gains
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R Class
2020 $19.58 (0.18) 4.52 4.34 (2.35) $21.57 24.37% 1.50% (0.97)% 85% $31,862 
2019 $21.43 (0.17) 2.64 2.47 (4.32) $19.58 16.66% 1.50% (0.88)% 82% $32,803 
2018 $22.13 (0.18) 1.59 1.41 (2.11) $21.43 6.62% 1.50% (0.80)% 85% $32,464 
2017 $20.10 (0.13) 3.92 3.79 (1.76) $22.13 20.16% 1.51% (0.65)% 56% $39,033 
2016 $23.48 (0.15) (0.50) (0.65) (2.73) $20.10 (2.75)% 1.50% (0.71)% 62% $43,875 
R5 Class
2020 $23.52 (0.04) 5.53 5.49 (2.35) $26.66 25.25% 0.80% (0.27)% 85% $1,339 
2019 $24.66 (0.04) 3.22 3.18 (4.32) $23.52 17.50% 0.80% (0.18)% 82% $3,663 
2018 $25.00 (0.04) 1.81 1.77 (2.11) $24.66 7.35% 0.80% (0.10)% 85% $3,053 
2017(4)
$22.69
(3)
2.31 2.31 $25.00 10.18%
0.81%(5)
(0.03)%(5)
56%(6)
$114 
R6 Class
2020 $23.84 (0.03) 5.64 5.61 (2.35) $27.10 25.43% 0.65% (0.12)% 85% $148,536 
2019 $24.90 (0.01) 3.27 3.26 (4.32) $23.84 17.68% 0.65% (0.03)% 82% $134,822 
2018 $25.19 0.02 1.80 1.82 (2.11) $24.90 7.51% 0.65% 0.05% 85% $132,651 
2017 $22.46 0.04 4.45 4.49 (1.76) $25.19 21.22% 0.66% 0.20% 56% $186,335 
2016 $25.72 0.03 (0.56) (0.53) (2.73) $22.46 (1.93)% 0.65% 0.14% 62% $123,681 




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)Per-share amount was less than $0.005.
(4)April 10, 2017 (commencement of sale) through October 31, 2017.
(5)Annualized.
(6)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Heritage Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Heritage Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.

28



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
29



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
30



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





31



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
32



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-year period, at its benchmark for the five-year period and below its benchmark for the three- and ten-year periods reviewed by the Board. The Board discussed the Fund's performance with the Advisor, including steps being taken to address underperformance, and was satisfied with the efforts being undertaken by the Advisor. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services
33



provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was below the median of the total expense ratios of the Fund’s peer expense universe. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.
34



Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
35



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



36



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates $511,302,077, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $27,423,288 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).

37



Notes

38



Notes

39



Notes




40








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
Business, Not-For-Profit, Employer-Sponsored Retirement Plans 1-800-345-3533
Banks and Trust Companies, Broker-Dealers, Financial Professionals, Insurance Companies 1-800-345-6488
Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90977 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
NT Growth Fund
G Class (ACLTX)


























Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
Performance
2
Portfolio Commentary
3
Fund Characteristics
5
Shareholder Fee Example
6
Schedule of Investments
7
Statement of Assets and Liabilities
11
Statement of Operations
12
Statement of Changes in Net Assets
13
Notes to Financial Statements
14
Financial Highlights
20
Report of Independent Registered Public Accounting Firm
21
Management
22
Approval of Management Agreement
25
Additional Information
29




















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




Performance
Total Returns as of October 31, 2020
    Average Annual Returns
  Ticker
Symbol
1 year 5 years 10 years Inception
Date
G Class ACLTX 27.44% 16.74% 15.07% 5/12/06
Russell 1000 Growth Index 29.22% 17.30% 16.29%
Fund returns would have been lower if a portion of the fees had not been waived.

Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
  CHART-CF9A89846F4B44F6A291.JPG
Value on October 31, 2020
G Class — $40,737
Russell 1000 Growth Index — $45,290
Ending value of G Class would have been lower if a portion of the fees had not been waived.
Total Annual Fund Operating Expenses
G Class 0.63%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.





Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
2



Portfolio Commentary

Portfolio Managers: Gregory Woodhams, Justin Brown and Scott Marolf

Senior financial analyst Scott Marolf was added to the fund’s portfolio management team in February of 2020.

Performance Summary

NT Growth returned 27.44%* for the 12 months ended October 31, 2020, lagging the 29.22% return of the fund’s benchmark, the Russell 1000 Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell 1000 Growth Index, all sectors posted gains except for energy, which struggled with the declining price of oil amid falling demand, and industrials, which declined modestly on concerns about global economic weakness. Consumer discretionary and information technology led the benchmark’s performance.

Stock selection in the health care, consumer discretionary and communication services sectors detracted from fund performance relative to the benchmark. Stock decisions in the industrials and information technology sectors benefited relative performance, as did underweighting industrials.

Health Care and Communication Services Stocks Led Detractors

Stock selection in the health care equipment and supplies industry weighed on relative performance in the health care sector. The industry felt the effects of stay-at-home mandates due to the pandemic as hospitals and individuals postponed voluntary procedures. In the consumer discretionary sector, our underweight to Tesla relative to the benchmark detracted. The electric car company’s stock outperformed due to solid fundamental reports and strong demand for its vehicles. Retail investors also reacted positively to the announcement of a five-for-one stock split.

In the communication services sector, entertainment companies such as The Walt Disney Co. struggled. Disney was forced to close its theme parks. The company’s weakness was exacerbated by the impact of delayed movie releases and a lack of live sports on its ESPN network. We maintained a position in Disney based on its growth in streaming and an eventual recovery in its cyclical media and theme park assets.

Elsewhere, Visa underperformed after the payments company reported declining revenues due primarily to weakness in cross-border transactions as a result of pandemic-related travel restrictions. We maintained a position in Visa based on our favorable view on payment networks. We were also underweight Apple, which detracted from performance. The consumer electronics company delivered solid results with strength in most work-from-home categories, including iPads and Macs, as well as solid growth in services. Also, the company split its stock four-for-one to make the equity more appealing to retail investors.

Dow was a significant detractor. The chemicals company faced the perfect storm of lower global gross domestic product having an impact on polyethylene demand and significantly lower oil prices diminishing Dow’s relative feedstock cost advantage. We eliminated our holding. The stock of multibrand restaurant owner Darden Restaurants fell sharply due to the social distancing restrictions implemented to fight the pandemic. We eliminated Darden on our belief it will take longer for some restaurants to fully recovery from the pandemic.



*Fund returns would have been lower if a portion of the fees had not been waived.
3



Industrials Aided Performance

Stock decisions among aerospace and defense companies and an underweight allocation to the industry benefited relative performance in the industrials sector. Our lighter exposure to The Boeing Co. aided results as the airplane manufacturer and defense contractor was hurt by the sharply reduced air travel, which curtailed demand for its planes. It also faced continuing difficulties with safety issues with its 737 MAX airplane. We eliminated Boeing during the first quarter of 2020.

In the information technology sector, stock selection in IT services helped performance, as did an overweight allocation to semiconductors and semiconductor equipment. Cloud computing firm Fastly was a key contributor. The company provides a variety of services, including a content delivery network that allows companies to cache data and other content that can then be retrieved by end users. Fastly benefited from the stay-at-home environment. PayPal Holdings outperformed. The payment services company reported better-than-expected earnings, helped by increased use of digital payments during the pandemic. Chipmaker NVIDIA reported solid results and guidance due to strength in its data center and gaming businesses. The data center business is being driven by the launch of new products that are based on a new architecture and a leading process node, which is driving better price/performance per chip. The company also announced the proposed acquisition of ARM Holdings, which has the ability to broaden NVIDIA’s reach in semiconductors. Microsoft was a key contributor. The software giant was buoyed by the breadth of its businesses, its transition to a subscription model and strength in its cloud division.

Other top contributors included Amazon. The retailer continued to benefit from the shift of consumer spending trends toward online purchasing. This is especially important for Amazon’s progress with consumables, including grocery and fresh foods, which has been a slower area of progress. Amazon could also benefit from potential rising demand for more cloud usage.

Outlook

We believe stock selection—rather than sector allocation or market timing via the use of cash—is the most efficient means of generating superior risk-adjusted returns. As a result of this approach, the portfolio’s sector and industry selection, as well as capitalization range allocations, are primarily due to identifying what we believe to be superior individual securities.

At period-end, our largest sector allocation relative to the benchmark was information technology. The largest underweight was health care.





4



Fund Characteristics 
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Microsoft Corp. 11.8%
Amazon.com, Inc. 9.6%
Apple, Inc. 8.8%
Alphabet, Inc., Class A 6.9%
Visa, Inc., Class A 4.4%
NVIDIA Corp. 3.5%
PayPal Holdings, Inc. 3.4%
Facebook, Inc., Class A 2.8%
Procter & Gamble Co. (The) 2.3%
UnitedHealth Group, Inc. 2.1%
Top Five Industries % of net assets
Software 17.6%
Internet and Direct Marketing Retail 10.8%
Interactive Media and Services 10.3%
IT Services 9.1%
Technology Hardware, Storage and Peripherals 8.8%
Types of Investments in Portfolio % of net assets
Common Stocks 99.7%
Temporary Cash Investments 0.2%
Temporary Cash Investments - Securities Lending Collateral 1.2%
Other Assets and Liabilities (1.1)%
5



Shareholder Fee Example

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
G Class $1,000 $1,193.30 $0.06 0.01%
Hypothetical
G Class $1,000 $1,025.09 $0.05 0.01%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
6



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 99.7%
Aerospace and Defense — 1.0%
Lockheed Martin Corp. 37,792  $ 13,232,113 
Auto Components — 1.2%
Aptiv plc 153,563  14,817,294 
Automobiles — 0.7%
Tesla, Inc.(1)
22,290  8,649,412 
Biotechnology — 3.4%
Amgen, Inc. 110,308  23,930,217 
CRISPR Therapeutics AG(1)(2)
65,708  6,033,309 
Vertex Pharmaceuticals, Inc.(1)
66,381  13,831,145 
43,794,671 
Building Products — 1.2%
Masco Corp. 233,735  12,528,196 
Trex Co., Inc.(1)
41,298  2,871,863 
15,400,059 
Capital Markets — 1.4%
S&P Global, Inc. 55,228  17,823,732 
Electrical Equipment — 1.5%
Ballard Power Systems, Inc.(1)(2)
274,292  4,051,293 
Generac Holdings, Inc.(1)
20,927  4,397,809 
Rockwell Automation, Inc. 48,342  11,462,855 
19,911,957 
Electronic Equipment, Instruments and Components — 1.8%
CDW Corp. 46,172  5,660,687 
Cognex Corp. 110,331  7,270,813 
Keysight Technologies, Inc.(1)
94,843  9,946,186 
22,877,686 
Entertainment — 1.6%
Liberty Media Corp.-Liberty Formula One, Class C(1)
119,422  4,314,717 
Take-Two Interactive Software, Inc.(1)
62,918  9,747,256 
Walt Disney Co. (The) 56,143  6,807,339 
20,869,312 
Equity Real Estate Investment Trusts (REITs) — 1.5%
SBA Communications Corp. 67,123  19,490,506 
Food Products — 1.6%
Beyond Meat, Inc.(1)
22,289  3,174,622 
Mondelez International, Inc., Class A 294,391  15,638,050 
Vital Farms, Inc.(1)
50,068  1,730,350 
20,543,022 
Health Care Equipment and Supplies — 2.4%
DexCom, Inc.(1)
18,613  5,948,343 
Edwards Lifesciences Corp.(1)
76,937  5,515,614 
IDEXX Laboratories, Inc.(1)
11,853  5,035,391 
Insulet Corp.(1)
13,573  3,016,599 
Intuitive Surgical, Inc.(1)
17,229  11,493,121 
31,009,068 
7



Shares Value
Health Care Providers and Services — 2.5%
Quest Diagnostics, Inc. 38,340  $ 4,682,848 
UnitedHealth Group, Inc. 88,118  26,888,326 
31,571,174 
Health Care Technology — 0.7%
Teladoc Health, Inc.(1)(2)
28,620  5,622,685 
Veeva Systems, Inc., Class A(1)
12,778  3,450,699 
9,073,384 
Hotels, Restaurants and Leisure — 1.5%
Chipotle Mexican Grill, Inc.(1)
9,229  11,088,459 
Domino's Pizza, Inc. 23,289  8,810,694 
19,899,153 
Household Products — 2.3%
Procter & Gamble Co. (The) 217,975  29,884,373 
Insurance — 0.8%
Progressive Corp. (The) 91,507  8,409,493 
Root, Inc., Class A(1)
36,800  882,096 
SelectQuote, Inc.(1)
89,844  1,547,114 
10,838,703 
Interactive Media and Services — 10.3%
Alphabet, Inc., Class A(1)
54,407  87,927,697 
Facebook, Inc., Class A(1)
137,329  36,132,633 
Twitter, Inc.(1)
198,132  8,194,739 
132,255,069 
Internet and Direct Marketing Retail — 10.8%
Amazon.com, Inc.(1)
40,516  123,012,653 
Chewy, Inc., Class A(1)(2)
146,627  9,032,223 
Expedia Group, Inc. 64,850  6,105,628 
138,150,504 
IT Services — 9.1%
Fastly, Inc., Class A(1)(2)
78,642  4,994,553 
Okta, Inc.(1)
18,447  3,870,734 
PayPal Holdings, Inc.(1)
233,857  43,527,803 
Snowflake, Inc., Class A(1)
138  34,503 
Twilio, Inc., Class A(1)
14,315  3,993,456 
VeriSign, Inc.(1)
21,257  4,053,710 
Visa, Inc., Class A 308,166  55,996,844 
116,471,603 
Life Sciences Tools and Services — 0.9%
Adaptive Biotechnologies Corp.(1)
104,451  4,813,102 
Agilent Technologies, Inc. 42,616  4,350,668 
Repligen Corp.(1)
12,916  2,151,418 
11,315,188 
Machinery — 0.4%
Cummins, Inc. 20,604  4,530,614 
Personal Products — 0.6%
Estee Lauder Cos., Inc. (The), Class A 34,111  7,492,822 
Pharmaceuticals — 2.5%
Merck & Co., Inc. 128,022  9,628,535 
Novo Nordisk A/S, B Shares 210,318  13,450,208 
Zoetis, Inc. 55,201  8,752,118 
31,830,861 
8



Shares Value
Road and Rail — 1.0%
Lyft, Inc., Class A(1)
115,417  $ 2,634,970 
Union Pacific Corp. 59,588  10,558,398 
13,193,368 
Semiconductors and Semiconductor Equipment — 7.8%
Advanced Micro Devices, Inc.(1)
160,104  12,054,230 
Analog Devices, Inc. 62,855  7,450,203 
ASML Holding NV 52,600  19,122,977 
Broadcom, Inc. 47,207  16,504,984 
NVIDIA Corp. 89,562  44,902,804 
100,035,198 
Software — 17.6%
Datadog, Inc., Class A(1)
53,843  4,886,252 
DocuSign, Inc.(1)
18,231  3,687,220 
JFrog Ltd.(1)
355  25,713 
Microsoft Corp. 749,768  151,805,527 
PagerDuty, Inc.(1)(2)
217,227  5,886,852 
salesforce.com, Inc.(1)
92,032  21,376,273 
Slack Technologies, Inc., Class A(1)
338,599  8,661,362 
Splunk, Inc.(1)
63,334  12,542,665 
Workday, Inc., Class A(1)
18,610  3,910,333 
Zendesk, Inc.(1)
122,993  13,644,843 
226,427,040 
Specialty Retail — 1.1%
Home Depot, Inc. (The) 23,305  6,215,677 
TJX Cos., Inc. (The) 161,819  8,220,405 
14,436,082 
Technology Hardware, Storage and Peripherals — 8.8%
Apple, Inc. 1,031,748  112,316,087 
Textiles, Apparel and Luxury Goods — 1.7%
NIKE, Inc., Class B 179,286  21,528,663 
TOTAL COMMON STOCKS
(Cost $837,384,802)
1,279,668,718 
TEMPORARY CASH INVESTMENTS — 0.2%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $925,834), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $910,886) 910,881 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 3.625%, 2/15/44, valued at $1,617,856), at 0.06%, dated 10/30/20,
due 11/2/20 (Delivery value $1,586,008)
1,586,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 99  99 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $2,496,980)
2,496,980 
TEMPORARY CASH INVESTMENTS - SECURITIES LENDING COLLATERAL(3) — 1.2%
State Street Navigator Securities Lending Government Money Market Portfolio
(Cost $15,064,521)
15,064,521  15,064,521 
TOTAL INVESTMENT SECURITIES — 101.1%
(Cost $854,946,303)
1,297,230,219 
OTHER ASSETS AND LIABILITIES — (1.1)% (14,514,082)
TOTAL NET ASSETS — 100.0% $ 1,282,716,137 
9



FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
EUR 677,357  USD 795,075  Credit Suisse AG 12/31/20 $ (5,042)
EUR 402,390  USD 477,863  Credit Suisse AG 12/31/20 (8,536)
EUR 482,868  USD 571,963  Credit Suisse AG 12/31/20 (8,771)
USD 16,187,640  EUR 13,790,800  Credit Suisse AG 12/31/20 102,776 
USD 514,281  EUR 438,158  Credit Suisse AG 12/31/20 3,237 
USD 520,812  EUR 440,394  Credit Suisse AG 12/31/20 7,160 
USD 849,815  EUR 722,067  Credit Suisse AG 12/31/20 7,634 
$ 98,458 

NOTES TO SCHEDULE OF INVESTMENTS
EUR - Euro
USD - United States Dollar
(1)Non-income producing.
(2)Security, or a portion thereof, is on loan. At the period end, the aggregate value of securities on loan was $29,565,239. The amount of securities on loan indicated may not correspond with the securities on loan identified because securities with pending sales are in the process of recall from the brokers.
(3)Investment of cash collateral from securities on loan. At the period end, the aggregate value of the collateral held by the fund was $31,772,212, which includes securities collateral of $16,707,691.


See Notes to Financial Statements.
10



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $839,881,782) — including $29,565,239 of securities on loan $ 1,282,165,698 
Investment made with cash collateral received for securities on loan, at value
(cost of $15,064,521)
15,064,521 
Total investment securities, at value (cost of $854,946,303) 1,297,230,219 
Receivable for investments sold 942,051 
Receivable for capital shares sold 636 
Unrealized appreciation on forward foreign currency exchange contracts 120,807 
Dividends and interest receivable 284,887 
Securities lending receivable 11,488 
1,298,590,088 
Liabilities
Payable for collateral received for securities on loan 15,064,521 
Payable for investments purchased 786,524 
Payable for capital shares redeemed 557 
Unrealized depreciation on forward foreign currency exchange contracts 22,349 
15,873,951 
Net Assets $ 1,282,716,137 
G Class Capital Shares, $0.01 Par Value
Shares authorized 780,000,000 
Shares outstanding 64,147,672 
Net Asset Value Per Share $ 20.00 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 688,736,770 
Distributable earnings 593,979,367 
$ 1,282,716,137 


See Notes to Financial Statements.
11



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $59,352) $ 8,765,781 
Interest 120,178 
Securities lending, net 99,827 
8,985,786 
Expenses:
Management fees 6,004,545 
Directors' fees and expenses 31,908 
Other expenses 40,677 
6,077,130 
Fees waived (6,004,545)
72,585 
Net investment income (loss) 8,913,201 
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 192,462,267 
Forward foreign currency exchange contract transactions (433,606)
Futures contract transactions 2,159,756 
Foreign currency translation transactions 1,594 
194,190,011 
Change in net unrealized appreciation (depreciation) on:
Investments 10,657,655 
Forward foreign currency exchange contracts 163,582 
Futures contracts (191,844)
Translation of assets and liabilities in foreign currencies 3,353 
10,632,746 
Net realized and unrealized gain (loss) 204,822,757 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 213,735,958 


See Notes to Financial Statements.
12



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ 8,913,201  $ 13,258,376 
Net realized gain (loss) 194,190,011  117,578,603 
Change in net unrealized appreciation (depreciation) 10,632,746  56,285,542 
Net increase (decrease) in net assets resulting from operations 213,735,958  187,122,521 
Distributions to Shareholders
From earnings (121,765,935) (183,752,693)
Capital Share Transactions
Proceeds from shares sold 642,945,523  131,041,452 
Proceeds from reinvestment of distributions 121,765,935  183,752,693 
Payments for shares redeemed (651,200,701) (400,315,276)
Net increase (decrease) in net assets from capital share transactions 113,510,757  (85,521,131)
Net increase (decrease) in net assets 205,480,780  (82,151,303)
Net Assets
Beginning of period 1,077,235,357  1,159,386,660 
End of period $ 1,282,716,137  $ 1,077,235,357 
Transactions in Shares of the Fund
Sold 32,808,941  7,637,963 
Issued in reinvestment of distributions 7,300,116  12,655,144 
Redeemed (35,290,362) (23,336,412)
Net increase (decrease) in shares of the fund 4,818,695  (3,043,305)


See Notes to Financial Statements.
13



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. NT Growth Fund (the fund) is one fund in a series issued by the corporation. The fund's investment objective is to seek long-term capital growth. The fund is not permitted to invest in securities issued by companies assigned the Global Industry Classification Standard or the Bloomberg Industry Classification Standard for the tobacco industry. The fund offers the G Class.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.
Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Exchange-traded futures contracts are valued at the settlement price as provided by the appropriate exchange. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.
If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.

14



The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.
Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.

15



Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.
Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

The following table reflects a breakdown of transactions accounted for as secured borrowings, the gross obligation by the type of collateral pledged, and the remaining contractual maturity of those transactions as of October 31, 2020.

Remaining Contractual Maturity of Agreements
Overnight and
Continuous
<30 days
Between
30 & 90 days
>90 days
Total
Securities Lending Transactions(1)
Common Stocks $ 15,064,521  —  —  —  $ 15,064,521 
Gross amount of recognized liabilities for securities lending transactions $ 15,064,521 

(1)Amount represents the payable for cash collateral received for securities on loan. This will generally be in the Overnight and Continuous column as the securities are typically callable on demand.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc., and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. Various funds issued by American Century Asset Allocation Portfolios, Inc. own, in aggregate, 57% of the shares of the fund. Related parties do not invest in the fund for the purpose of exercising management or control.
Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee). The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), and extraordinary expenses. The fee is computed and accrued daily based on the daily net assets of the fund and paid monthly in arrears. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets). The strategy assets of the fund also include the assets of Growth Fund, one fund in a series issued by the corporation. The management fee schedule ranges from 0.450% to 0.640%. The investment advisor agreed to waive the fund's management fee in its entirety. The investment advisor expects this waiver to remain in effect permanently and cannot terminate it without the approval of the Board of Directors. The effective annual management fee for the period ended October 31, 2020 was 0.62% before waiver and 0.00% after waiver.
16



Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.
Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $703,032 and $641,618, respectively. The effect of interfund transactions on the Statement of Operations was $(149,244) in net realized gain (loss) on investment transactions.

4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $396,463,476 and $935,959,191, respectively.

On July 22, 2020, the fund received investment securities valued at $571,173,873 from a purchase in kind from other products managed by the fund’s investment advisor. A purchase in kind occurs when a fund receives securities into its portfolio in lieu of cash as payment from a purchasing shareholder.

5. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 1,247,095,533  $ 32,573,185  — 
Temporary Cash Investments 99  2,496,881  — 
Temporary Cash Investments - Securities Lending Collateral 15,064,521  —  — 
$ 1,262,160,153  $ 35,070,066  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 120,807  — 
      
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 22,349  — 


17



6. Derivative Instruments
Equity Price Risk — The fund is subject to equity price risk in the normal course of pursuing its investment objectives. A fund may enter into futures contracts based on an equity index in order to manage its exposure to changes in market conditions. A fund may purchase futures contracts to gain exposure to increases in market value or sell futures contracts to protect against a decline in market value. Upon entering into a futures contract, a fund is required to deposit either cash or securities in an amount equal to a certain percentage of the contract value (initial margin). Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the contract value and is recorded as unrealized gains and losses. A fund recognizes a realized gain or loss when the contract is closed or expires. Net realized and unrealized gains or losses occurring during the holding period of futures contracts are a component of net realized gain (loss) on futures contract transactions and change in net unrealized appreciation (depreciation) on futures contracts, respectively. One of the risks of entering into futures contracts is the possibility that the change in value of the contract may not correlate with the changes in value of the underlying securities. The fund's average notional exposure to equity price risk derivative instruments held during the period was $24,005,676 futures contracts purchased.
Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $16,388,568.
Value of Derivative Instruments as of October 31, 2020
Asset Derivatives
Liability Derivatives
Type of Risk Exposure Location on Statement of Assets and Liabilities
Value
Location on Statement of Assets and Liabilities
Value
Foreign Currency Risk Unrealized appreciation on forward foreign currency exchange contracts $ 120,807  Unrealized depreciation on forward foreign currency exchange contracts $ 22,349 

Effect of Derivative Instruments on the Statement of Operations for the Year Ended October 31, 2020
Net Realized Gain (Loss)
Change in Net Unrealized
Appreciation (Depreciation)
Type of Risk Exposure Location on Statement of Operations
Value
Location on Statement of Operations
Value
Equity Price Risk Net realized gain (loss) on futures contract transactions $ 2,159,756  Change in net unrealized appreciation (depreciation) on futures contracts $ (191,844)
Foreign Currency Risk Net realized gain (loss) on forward foreign currency exchange contract transactions (433,606) Change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts 163,582 
$ 1,726,150  $ (28,262)


18



7. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.
The fund is owned by a relatively small number of shareholders, and in the event such shareholders redeem, the ongoing operations of the fund may be at risk.

8. Federal Tax Information

On December 8, 2020, the fund declared and paid per-share distributions of $2.3161 and $0.1036 from net realized gains and net investment income, respectively to shareholders of record on December 7, 2020.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 16,872,974  $ 30,194,756 
Long-term capital gains $ 104,892,961  $ 153,557,937 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.

The reclassifications, which are primarily due to tax equalization, were made to capital $43,958,771 and distributable earnings $(43,958,771).
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 857,845,519 
Gross tax appreciation of investments $ 452,530,797 
Gross tax depreciation of investments (13,146,097)
Net tax appreciation (depreciation) of investments 439,384,700 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 2,283 
Net tax appreciation (depreciation) $ 439,386,983 
Undistributed ordinary income $ 7,815,156 
Accumulated long-term gains $ 146,777,228 
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.
19



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)(1)
Net Realized and Unrealized Gain (Loss) Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
G Class
2020 $18.16 0.17 4.29 4.46 (0.27) (2.35) (2.62) $20.00 27.44% 0.01% 0.63% 0.92% 0.30% 40% $1,282,716
2019 $18.59 0.20 2.41 2.61 (0.22) (2.82) (3.04) $18.16 18.16%
0.00%(3)
0.63% 1.20% 0.57% 43% $1,077,235
2018 $18.38 0.20 1.80 2.00 (0.13) (1.66) (1.79) $18.59 11.50%
0.00%(3)
0.62% 1.09% 0.47% 53% $1,159,387
2017 $14.62 0.11 4.00 4.11 (0.12) (0.23) (0.35) $18.38 28.64% 0.56% 0.74% 0.67% 0.49% 64% $1,364,741
2016 $15.57 0.11 (0.06) 0.05 (0.07) (0.93) (1.00) $14.62 0.49% 0.78% 0.78% 0.74% 0.74% 60% $1,104,817

Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day. Total returns for periods less than one year are not annualized.
(3)Ratio was less than 0.005%.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of NT Growth Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of NT Growth Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.
21



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
22



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
23



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





24



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
25



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-, three-, and five-year periods and below its benchmark for the ten-year period reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
26



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was above the median of the total expense ratios of the Fund’s peer expense universe
27



and was within the range of its peer expense group. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
28



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



29



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $10,986,642, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $147,693,058, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund hereby designates $4,508,710 as qualified short-term capital gain distributions for purposes of Internal Revenue Code Section 871 for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $43,958,771 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).






































30



Notes






















































31



Notes















































32








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
Business, Not-For-Profit, Employer-Sponsored Retirement Plans 1-800-345-3533
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Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90986 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
NT Heritage Fund
G Class (ACLWX)


























Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
 
Performance
2
Portfolio Commentary
3
Fund Characteristics
5
Shareholder Fee Example
6
Schedule of Investments
7
Statement of Assets and Liabilities
11
Statement of Operations
12
Statement of Changes in Net Assets
13
Notes to Financial Statements
14
Financial Highlights
20
Report of Independent Registered Public Accounting Firm
21
Management
22
Approval of Management Agreement
25
Additional Information
29



















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




Performance
Total Returns as of October 31, 2020
      Average Annual Returns  
  Ticker
Symbol
1 year 5 years 10 years Inception
Date
G Class ACLWX 25.77% 13.81% 12.72% 5/12/06
Russell Midcap Growth Index 21.14% 14.14% 14.11%
Fund returns would have been lower if a portion of the fees had not been waived.
Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
  CHART-D47A8074C70846D5B651.JPG
Value on October 31, 2020
G Class — $33,135
Russell Midcap Growth Index — $37,485
Ending value of G Class would have been lower if a portion of the fees had not been waived.

Total Annual Fund Operating Expenses
G Class 0.66%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.







Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
2



Portfolio Commentary
 
Portfolio Managers: Rob Brookby and Nalin Yogasundram

Performance Summary

NT Heritage returned 25.77%* for the 12 months ended October 31, 2020, outpacing the 21.14% return of the fund’s benchmark, the Russell Midcap Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell Midcap Growth Index, health care and information technology were the top-performing sectors. Energy posted a significant loss as oversupply and declining oil prices weighed on the sector.

The information technology and health care sectors led outperformance relative to the benchmark due to stock selection. Stock decisions in the communication services and consumer discretionary sectors detracted.

Information Technology Led Performance

Stock selection among IT services companies led performance in the information technology sector, which was far and away the fund’s top-performing sector relative to the benchmark. Square was a significant contributor. The payments company outperformed as its main businesses—small retailers and peer to peer—both benefited from the stay-at-home restrictions. Coffee shops and restaurants have had to adjust to new business models, and individuals are increasingly using digital payments. We see these as secular trends that have been accelerated by the pandemic. Twilio was another top contributor. The company’s software allows developers to create apps that communicate with one another. In addition to its apps that support travel industries, its software enables apps that allow videoconferencing between doctors and patients, which has taken hold during the pandemic’s stay-at-home mandates.

Advanced Micro Devices aided performance. The chipmaker beat earnings expectations as it benefited from increased semiconductor demand for gaming as well as missteps by its large competitor Intel. Another top contributor, RingCentral, helps companies move their telecommunications into the cloud, providing features such as voice, video, data and call forwarding of business calls to mobile phones. We think the company has a long-term tailwind but was also seen as a beneficiary of the work-from-home environment during the pandemic.

Other significant contributors included Immunomedics, whose stock price climbed following Gilead Sciences’ announcement that it would acquire the maker of cancer drugs. As a result of the deal, Immunomedics was eliminated. Peloton Interactive, a leader in home fitness, benefited from the stay-at-home environment created by COVID-19. We think the trend will continue after the pandemic, and Peloton is expanding its offerings into lower-priced treadmills and bikes.

Communication Services Stocks Detracted

Stock selection among interactive media and services and entertainment companies weighed on relative performance. Companies such as Live Nation Entertainment fell as the pandemic curtailed live events. We eliminated our holding. We eliminated Pinterest during the fourth quarter of 2019



*Fund returns would have been lower if a portion of the fees had not been waived.

3



and so were underweight the social media stock relative to the benchmark over the course of the fiscal year. This hampered performance as Pinterest posted strong earnings and user growth.

Underweighting internet and direct marketing retail stocks hurt performance in the consumer discretionary sector as stay-at-home mandates gave a boost to the industry. Stock choices among distributors also detracted. LKQ, a provider of aftermarket automobile parts, declined as shelter-in-place restrictions in the U.S. and Europe caused people to drive fewer miles. We think this is a near-term issue and that, as restrictions are lifted, miles driven will increase, aided by low gasoline prices and ongoing weakness in air travel.

Other significant detractors included DocuSign, which was underweight relative to the benchmark. The cloud-based electronic signature company outperformed as it benefited from increased demand for its services because of social distancing mandates. Another detractor was Japan-based Shiseido, a skin care and cosmetics maker that primarily sells in duty-free shops in China and Japan. The pandemic hurt the travel industry, but we saw a pickup in China and took the opportunity to add to our position. SelectQuote, an online direct-to-consumer insurance broker, has exposure to life insurance, home and automobile insurance, and senior health insurance through Medicare Advantage. The stock lagged on concerns about profitability under competitive pressures as Walmart enters the field.

Outlook

Our process uses a combined top-down, bottom-up fundamental framework aimed at identifying mid-cap companies producing attractive, sustainable growth. We seek to reduce unintended, nonfundamental risks and align the portfolio with fundamental, company-specific risks that we believe will be rewarded over time. As a result of this approach, our sector and industry allocations reflect where we are finding opportunities at a given time.

Consumer discretionary ended the period as the portfolio’s largest overweight relative to the benchmark. Communication services ended as the largest underweight sector.



4



Fund Characteristics
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Cadence Design Systems, Inc. 3.1%
Xilinx, Inc. 2.6%
Cognex Corp. 2.5%
Veeva Systems, Inc., Class A 2.2%
Twilio, Inc., Class A 2.2%
Splunk, Inc. 2.1%
Align Technology, Inc. 2.1%
Square, Inc., Class A 2.0%
Skyworks Solutions, Inc. 2.0%
Teleflex, Inc. 1.9%
Top Five Industries % of net assets
Software 16.5%
Semiconductors and Semiconductor Equipment 8.3%
Health Care Equipment and Supplies 7.5%
Electronic Equipment, Instruments and Components 4.2%
IT Services 4.2%
Types of Investments in Portfolio % of net assets
Common Stocks 99.5%
Temporary Cash Investments 0.5%
Temporary Cash Investments - Securities Lending Collateral 0.7%
Other Assets and Liabilities (0.7)%



5



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
G Class $1,000 $1,278.70 $0.06 0.01%
Hypothetical
G Class $1,000 $1,025.09 $0.05 0.01%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
6



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 99.5%
Auto Components — 1.1%
Aptiv plc 102,697  $ 9,909,234 
Beverages — 1.3%
Boston Beer Co., Inc. (The), Class A(1)
11,864  12,328,832 
Biotechnology — 3.8%
ACADIA Pharmaceuticals, Inc.(1)
137,382  6,381,394 
Alnylam Pharmaceuticals, Inc.(1)
71,682  8,814,735 
Argenx SE, ADR(1)
25,583  6,347,910 
Seagen, Inc.(1)
52,918  8,826,722 
Turning Point Therapeutics, Inc.(1)
57,525  5,303,230 
35,673,991 
Building Products — 2.9%
Fortune Brands Home & Security, Inc. 168,296  13,610,098 
Trane Technologies plc 99,966  13,270,486 
26,880,584 
Capital Markets — 3.7%
LPL Financial Holdings, Inc. 119,308  9,536,288 
MarketAxess Holdings, Inc. 21,303  11,479,122 
MSCI, Inc. 39,606  13,855,763 
34,871,173 
Chemicals — 0.5%
Albemarle Corp. 51,096  4,762,658 
Communications Equipment — 2.2%
Arista Networks, Inc.(1)
38,469  8,036,174 
F5 Networks, Inc.(1)
96,392  12,814,353 
20,850,527 
Containers and Packaging — 3.0%
Avery Dennison Corp. 96,188  13,311,457 
Ball Corp. 168,707  15,014,923 
28,326,380 
Distributors — 0.8%
LKQ Corp.(1)
234,579  7,504,182 
Diversified Consumer Services — 0.3%
Chegg, Inc.(1)
33,684  2,473,753 
Electrical Equipment — 4.1%
AMETEK, Inc. 131,036  12,867,735 
Generac Holdings, Inc.(1)
18,900  3,971,835 
nVent Electric plc 380,545  6,868,838 
Rockwell Automation, Inc. 27,352  6,485,706 
Sensata Technologies Holding plc(1)
195,476  8,544,256 
38,738,370 
Electronic Equipment, Instruments and Components — 4.2%
Cognex Corp. 347,831  22,922,063 
Keysight Technologies, Inc.(1)
158,759  16,649,056 
39,571,119 
Entertainment — 2.5%
Roku, Inc.(1)
57,037  11,544,289 
7



Shares Value
Zynga, Inc., Class A(1)
1,270,048  $ 11,417,731 
22,962,020 
Health Care Equipment and Supplies — 7.5%
Align Technology, Inc.(1)
45,138  19,232,399 
DexCom, Inc.(1)
22,582  7,216,756 
IDEXX Laboratories, Inc.(1)
28,857  12,259,031 
Masimo Corp.(1)
59,703  13,362,725 
Teleflex, Inc. 55,761  17,744,823 
69,815,734 
Health Care Providers and Services — 3.2%
Amedisys, Inc.(1)
54,887  14,215,733 
Encompass Health Corp. 255,730  15,678,806 
29,894,539 
Health Care Technology — 3.1%
Teladoc Health, Inc.(1)(2)
42,166  8,283,932 
Veeva Systems, Inc., Class A(1)
77,574  20,948,859 
29,232,791 
Hotels, Restaurants and Leisure — 2.9%
Chipotle Mexican Grill, Inc.(1)
14,284  17,161,940 
Las Vegas Sands Corp. 215,493  10,356,594 
27,518,534 
Household Durables — 1.3%
D.R. Horton, Inc. 174,721  11,673,110 
Insurance — 0.7%
SelectQuote, Inc.(1)
371,977  6,405,444 
Interactive Media and Services — 1.6%
Match Group, Inc.(1)
125,989  14,712,995 
Internet and Direct Marketing Retail — 1.4%
Chewy, Inc., Class A(1)(2)
107,613  6,628,961 
Wayfair, Inc., Class A(1)
25,605  6,350,808 
12,979,769 
IT Services — 4.2%
Square, Inc., Class A(1)
120,549  18,670,629 
Twilio, Inc., Class A(1)
74,405  20,756,763 
39,427,392 
Leisure Products — 1.0%
Peloton Interactive, Inc., Class A(1)
84,495  9,312,194 
Life Sciences Tools and Services — 2.7%
Mettler-Toledo International, Inc.(1)
17,665  17,628,080 
Repligen Corp.(1)
45,646  7,603,254 
25,231,334 
Machinery — 2.7%
Graco, Inc. 175,966  10,892,295 
Parker-Hannifin Corp. 68,997  14,376,215 
25,268,510 
Personal Products — 1.3%
Shiseido Co. Ltd. 201,700  12,486,108 
Pharmaceuticals — 1.9%
Horizon Therapeutics plc(1)
140,023  10,491,924 
Jazz Pharmaceuticals plc(1)
47,252  6,809,013 
17,300,937 
Professional Services — 2.3%
CoStar Group, Inc.(1)
10,279  8,465,887 
8



Shares Value
Verisk Analytics, Inc. 74,600  $ 13,276,562 
21,742,449 
Road and Rail — 0.8%
J.B. Hunt Transport Services, Inc. 63,554  7,737,064 
Semiconductors and Semiconductor Equipment — 8.3%
Advanced Micro Devices, Inc.(1)
103,722  7,809,229 
Marvell Technology Group Ltd. 349,102  13,094,816 
Skyworks Solutions, Inc. 131,863  18,630,923 
Teradyne, Inc. 157,275  13,816,609 
Xilinx, Inc. 205,211  24,356,494 
77,708,071 
Software — 16.5%
Atlassian Corp. plc, Class A(1)
41,193  7,893,403 
Cadence Design Systems, Inc.(1)
263,223  28,788,700 
Coupa Software, Inc.(1)
32,984  8,829,817 
DocuSign, Inc.(1)
61,772  12,493,387 
Envestnet, Inc.(1)
100,599  7,719,967 
HubSpot, Inc.(1)
48,687  14,122,638 
Manhattan Associates, Inc.(1)
177,865  15,207,457 
Palo Alto Networks, Inc.(1)
69,025  15,267,640 
RingCentral, Inc., Class A(1)
48,722  12,586,841 
Slack Technologies, Inc., Class A(1)
455,708  11,657,011 
Splunk, Inc.(1)
99,359  19,677,056 
154,243,917 
Specialty Retail — 3.4%
Burlington Stores, Inc.(1)
68,617  13,282,879 
Five Below, Inc.(1)
65,204  8,694,301 
Lithia Motors, Inc., Class A 41,496  9,526,237 
31,503,417 
Textiles, Apparel and Luxury Goods — 1.5%
lululemon athletica, Inc.(1)
43,831  13,994,800 
Trading Companies and Distributors — 0.8%
W.W. Grainger, Inc. 21,296  7,454,026 
TOTAL COMMON STOCKS
(Cost $763,621,592)
930,495,958 
TEMPORARY CASH INVESTMENTS — 0.5%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $1,768,181), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $1,739,632) 1,739,623 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 3.625%, 2/15/44, valued at $3,091,689), at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $3,031,015) 3,031,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 189  189 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $4,770,812)
4,770,812 
TEMPORARY CASH INVESTMENTS - SECURITIES LENDING COLLATERAL(3) — 0.7%
State Street Navigator Securities Lending Government Money Market Portfolio
(Cost $6,515,019)
6,515,019  6,515,019 
TOTAL INVESTMENT SECURITIES — 100.7%
(Cost $774,907,423)
941,781,789 
OTHER ASSETS AND LIABILITIES — (0.7)% (6,463,956)
TOTAL NET ASSETS — 100.0% $ 935,317,833 
9



FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
JPY 32,477,040  USD 308,232  Bank of America N.A. 12/30/20 $ 2,245 
JPY 33,873,750  USD 324,137  Bank of America N.A. 12/30/20 (307)
USD 11,318,851  JPY 1,187,488,980  Bank of America N.A. 12/30/20 (33,420)
USD 536,475  JPY 56,646,000  Bank of America N.A. 12/30/20 (5,055)
USD 262,734  JPY 27,756,540  Bank of America N.A. 12/30/20 (2,615)
$ (39,152)

NOTES TO SCHEDULE OF INVESTMENTS
ADR - American Depositary Receipt
JPY - Japanese Yen
USD - United States Dollar
(1)Non-income producing.
(2)Security, or a portion thereof, is on loan. At the period end, the aggregate value of securities on loan was $8,954,851. The amount of securities on loan indicated may not correspond with the securities on loan identified because securities with pending sales are in the process of recall from the brokers.
(3)Investment of cash collateral from securities on loan. At the period end, the aggregate value of the collateral held by the fund was $9,473,581, which includes securities collateral of $2,958,562.


See Notes to Financial Statements.
10



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $768,392,404) — including $8,954,851 of securities on loan $ 935,266,770 
Investment made with cash collateral received for securities on loan, at value
(cost of $6,515,019)
6,515,019 
Total investment securities, at value (cost of $774,907,423) 941,781,789 
Receivable for investments sold 899,645 
Receivable for capital shares sold 744 
Unrealized appreciation on forward foreign currency exchange contracts 2,245 
Dividends and interest receivable 98,255 
Securities lending receivable 2,714 
$ 942,785,392 
Liabilities
Payable for collateral received for securities on loan 6,515,019 
Payable for investments purchased 911,078 
Payable for capital shares redeemed 65 
Unrealized depreciation on forward foreign currency exchange contracts 41,397 
7,467,559 
Net Assets $ 935,317,833 
G Class Capital Shares, $0.01 Par Value
Shares authorized 600,000,000 
Shares outstanding 66,173,094 
Net Asset Value Per Share
$ 14.13 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 679,959,022 
Distributable earnings 255,358,811 
$ 935,317,833 


See Notes to Financial Statements.

11



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $3,542) $ 3,396,451 
Interest 35,004 
Securities lending, net 8,669 
3,440,124 
Expenses:
Management fees 4,383,893 
Directors' fees and expenses 22,086 
Other expenses 17,423 
4,423,402 
Fees waived (4,383,893)
39,509 
Net investment income (loss) 3,400,615 
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 101,754,998 
Forward foreign currency exchange contract transactions (200,297)
Foreign currency translation transactions (1,175)
101,553,526 
Change in net unrealized appreciation (depreciation) on:
Investments 52,062,972 
Forward foreign currency exchange contracts (51,632)
Translation of assets and liabilities in foreign currencies 23 
52,011,363 
Net realized and unrealized gain (loss) 153,564,889 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 156,965,504 


See Notes to Financial Statements.

12



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets
October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ 3,400,615  $ 3,852,250 
Net realized gain (loss) 101,553,526  80,423,875 
Change in net unrealized appreciation (depreciation) 52,011,363  20,173,100 
Net increase (decrease) in net assets resulting from operations 156,965,504  104,449,225 
Distributions to Shareholders
From earnings (81,790,080) (142,583,485)
Capital Share Transactions
Proceeds from shares sold 470,785,649  49,849,275 
Proceeds from reinvestment of distributions 81,790,080  142,583,485 
Payments for shares redeemed (294,257,396) (244,279,493)
Net increase (decrease) in net assets from capital share transactions 258,318,333  (51,846,733)
Net increase (decrease) in net assets 333,493,757  (89,980,993)
Net Assets
Beginning of period 601,824,076  691,805,069 
End of period $ 935,317,833  $ 601,824,076 
Transactions in Shares of the Fund
Sold 35,788,482  4,017,174 
Issued in reinvestment of distributions 6,931,363  13,992,491 
Redeemed (22,986,369) (19,173,722)
Net increase (decrease) in shares of the fund 19,733,476  (1,164,057)


See Notes to Financial Statements.

13



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. NT Heritage Fund (the fund) is one fund in a series issued by the corporation. The fund's investment objective is to seek long-term capital growth. The fund is not permitted to invest in securities issued by companies assigned the Global Industry Classification Standard or the Bloomberg Industry Classification Standard for the tobacco industry. The fund offers the G Class.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.
Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.
If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.
The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between
14



domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.
Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.
Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).

15



Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.
Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

The following table reflects a breakdown of transactions accounted for as secured borrowings, the gross obligation by the type of collateral pledged, and the remaining contractual maturity of those transactions as of October 31, 2020.
Remaining Contractual Maturity of Agreements
Overnight and
Continuous
<30 days
Between
30 & 90 days
>90 days
Total
Securities Lending Transactions(1)
Common Stocks $ 6,515,019  —  —  —  $ 6,515,019 
Gross amount of recognized liabilities for securities lending transactions $ 6,515,019 

(1)Amount represents the payable for cash collateral received for securities on loan. This will generally be in the Overnight and Continuous column as the securities are typically callable on demand.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc., and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. Various funds issued by American Century Asset Allocation Portfolios, Inc. own, in aggregate, 55% of the shares of the fund. Related parties do not invest in the fund for the purpose of exercising management or control.
Management Fees —The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee). The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), and extraordinary expenses. The fee is computed and accrued daily based on the daily net assets of the fund and paid monthly in arrears. The annual management fee is 0.65%. The investment advisor agreed to waive the fund's management fee in its entirety. The investment advisor expects this waiver to remain in effect permanently and cannot terminate it without the approval of the Board of Directors. The annual management fee for the period ended October 31, 2020 was 0.00% after waiver.
Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.


16



Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $604,985 and $2,345,535, respectively. The effect of interfund transactions on the Statement of Operations was $384,674 in net realized gain (loss) on investment transactions.
4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $619,188,041 and $842,313,556, respectively.

On July 22, 2020, the fund received investment securities valued at $409,456,297 from a purchase in kind from other products managed by the fund's investment advisor. A purchase in kind occurs when a fund receives securities into its portfolio in lieu of cash as payment from a purchasing shareholder.

5. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 918,009,850  $ 12,486,108  — 
Temporary Cash Investments 189  4,770,623  — 
Temporary Cash Investments - Securities Lending Collateral 6,515,019  —  — 
$ 924,525,058  $ 17,256,731  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 2,245  — 
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 41,397  — 

17



6. Derivative Instruments

Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $8,239,079.
The value of foreign currency risk derivative instruments as of October 31, 2020, is disclosed on the Statement of Assets and Liabilities as an asset of $2,245 in unrealized appreciation on forward foreign currency exchange contracts and a liability of $41,397 in unrealized depreciation on forward foreign currency exchange contracts. For the year ended October 31, 2020, the effect of foreign currency risk derivative instruments on the Statement of Operations was $(200,297) in net realized gain (loss) on forward foreign currency exchange contract transactions and $(51,632) in change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts.

7. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.
The fund is owned by a relatively small number of shareholders, and in the event such shareholders redeem, the ongoing operations of the fund may be at risk.
The fund invests in common stocks of small companies. Because of this, the fund may be subject to greater risk and market fluctuations than a fund investing in larger, more established companies.

8. Federal Tax Information

On December 8, 2020, the fund declared and paid per-share distributions of $1.4906 and $0.0510 from net
realized gains and net investment income, respectively to shareholders of record on December 7, 2020.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 2,988,466  $ 23,908,173 
Long-term capital gains $ 78,801,614  $ 118,675,312 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
The reclassifications, which are primarily due to tax equalization, were made to capital $10,582,984 and
distributable earnings $(10,582,984).
18



As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 782,269,275 
Gross tax appreciation of investments $ 177,004,696 
Gross tax depreciation of investments (17,492,182)
Net tax appreciation (depreciation) of investments 159,512,514 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 23 
Net tax appreciation (depreciation) $ 159,512,537 
Undistributed ordinary income $ 4,462,077 
Accumulated long-term gains $ 91,384,197 
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.
19



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
G Class
2020 $12.96 0.06 2.93 2.99 (0.07) (1.75) (1.82) $14.13 25.77% 0.01% 0.66% 0.50% (0.15)% 91% $935,318
2019 $14.53 0.08 1.66 1.74 (0.12) (3.19) (3.31) $12.96 18.18% 0.01% 0.66% 0.62% (0.03)% 92% $601,824
2018 $14.41 0.10 1.05 1.15 (0.05) (0.98) (1.03) $14.53 8.19%
0.00%(3)
0.65% 0.71% 0.06% 90% $691,805
2017 $12.31 0.04 2.50 2.54 (0.44) (0.44) $14.41 21.29% 0.58% 0.76% 0.27% 0.09% 67% $822,910
2016 $13.65
(4)
(0.28) (0.28) (1.06) (1.06) $12.31 (2.01)% 0.80% 0.80% (0.02)% (0.02)% 73% $649,951
Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day. Total returns for periods less than one year are not annualized.
(3)Ratio was less than 0.005%.
(4)Per-share amount was less than $0.005.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of NT Heritage Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of NT Heritage Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.
21



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
22



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
23



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





24



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
25



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-year period and below its benchmark for the three-, five-, and ten-year periods reviewed by the Board. The Board discussed the Fund's performance with the Advisor, including steps being taken to address underperformance, and was satisfied with the efforts being undertaken by the Advisor. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services
26



provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was below the median of the total expense ratios of the Fund’s peer expense universe. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.
27



Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
28



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



29



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $2,170,721, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $88,891,558, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund hereby designates $195,059 as qualified short-term capital gain distributions for purposes of Internal Revenue Code Section 871 for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $10,582,984 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).

30



Notes
31



Notes




32








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
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Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90987 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Select Fund
Investor Class (TWCIX)
I Class (TWSIX)
Y Class (ASLWX)
A Class (TWCAX)
C Class (ACSLX)
R Class (ASERX)
R5 Class (ASLGX)
R6 Class (ASDEX)
















Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
 
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
13
Statement of Operations
14
Statement of Changes in Net Assets
15
Notes to Financial Statements
16
Financial Highlights
24
Report of Independent Registered Public Accounting Firm
28
Management
29
Approval of Management Agreement
32
Additional Information
36

















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
 
Total Returns as of October 31, 2020
    Average Annual Returns
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class TWCIX 26.10% 15.52% 14.93% 6/30/71
Russell 1000 Growth Index 29.22% 17.30% 16.29%
I Class TWSIX 26.35% 15.75% 15.16% 3/13/97
Y Class ASLWX 26.55% 18.78% 4/10/17
A Class TWCAX 8/8/97
No sales charge 25.79% 15.23% 14.64%
With sales charge 18.56% 13.87% 13.97%
C Class ACSLX 24.85% 14.37% 13.79% 1/31/03
R Class ASERX 25.48% 14.95% 14.36% 7/29/05
R5 Class ASLGX 26.34% 18.58% 4/10/17
R6 Class ASDEX 26.54% 15.92% 15.97% 7/26/13
Average annual returns since inception are presented when ten years of performance history is not available.
Although the fund’s actual inception date was October 31,1958, the Investor Class inception date corresponds with the investment advisor’s implementation of its current investment philosophy and practices.
Fund returns would have been lower if a portion of the fees had not been waived.


Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.














Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-51E0C2A5C86A486FAB41.JPG
Value on October 31, 2020
Investor Class — $40,247
Russell 1000 Growth Index — $45,290
Ending value of Investor Class would have been lower if a portion of the fees had not been waived.


Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class
0.99% 0.79% 0.64% 1.24% 1.99% 1.49% 0.79% 0.64%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary
 
Portfolio Managers: Keith Lee, Michael Li and Chris Krantz

Performance Summary

Select returned 26.10%* for the 12 months ended October 31, 2020, lagging the 29.22% return of the fund’s benchmark, the Russell 1000 Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell 1000 Growth Index, consumer discretionary and information technology led the benchmark’s performance. At the other end of the spectrum, the energy sector struggled with the declining price of oil amid a sharp slowdown in economic growth and falling energy demand.

Stock selection and an underweight allocation to information technology stocks relative to the benchmark detracted from performance. Stock choices in the consumer discretionary sector also weighed on relative performance. Positioning in the industrials and health care sectors benefited relative performance the most.

Information Technology Stocks Led Detractors

In the information technology sector, stock selection in the semiconductors and semiconductor equipment industry detracted the most from performance compared with the benchmark. We did not own several stocks in the industry that performed well, including chipmaker NVIDIA, which is a benchmark component. The company reported strong quarterly results and raised guidance due to strength in its data center and gaming businesses. Among IT services stocks, digital payments company Mastercard underperformed as transaction volumes declined along with economic activity. Revenues declined further because of weakness in cross-border transactions as a result of pandemic-related travel restrictions.

Elsewhere, our lighter relative exposure to Tesla hampered performance as the electric car company outperformed. Tesla benefited from solid fundamental reports and strong demand for its vehicles. The company reported better-than-expected production numbers, successfully launched the Model Y and announced plans to ramp up production of its commercial Tesla Semi. We had some exposure to the stock, but less than the benchmark. The stock of The TJX Cos. underperformed as the off-price retailer temporarily closed its stores due to the pandemic. We like the long-term prospects for TJX as traditional mall retailers close their shops and consumers look for value. Our holding of The Walt Disney Co. detracted on concerns that the pandemic would significantly impact the global entertainment company. Disney closed its amusement parks in line with social distancing mandates.

Industrials Stocks Aided Relative Performance

A key contribution to performance compared with the benchmark came from avoiding many poor-performing stocks in the aerospace and defense industry. Elsewhere in the industrials sector, stock decisions in the industrial conglomerates and road and rail industries also contributed positively.




*All fund returns referenced in this commentary are for Investor Class shares. Fund returns would have been lower if a portion of the fees had not been waived. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.
5



Among leading individual contributors to performance was PayPal Holdings. The stock price of the leader in online payments benefited from the increasing demand for digital transactions, a secular trend that has been aided by stay-at-home restrictions during the pandemic.

Regeneron Pharmaceuticals was another major contributor to relative performance. The biotechnology company is engaged in the discovery and development of medicines for the treatment of serious diseases, and it maintains one of the world’s most comprehensive genetic databases. Regeneron’s treatment for COVID-19 patients showed benefits for patients in late-stage clinical trials. Not owning benchmark component Merck & Co. also helped relative performance. Merck lagged other pharmaceutical companies because its prescribing trends were more affected by a downturn in doctor visits and elective procedures during the height of the COVID-19-related shutdowns.

Elsewhere, Apple’s stock price outperformed as growth in its services and wearable devices has taken the pressure off of iPhone sales as the driver of earnings. It also benefited relative performance to avoid benchmark components The Coca-Cola Co. and PepsiCo. These large beverage companies saw decreased demand due to the pandemic, which curtailed restaurant visits and live events, significant sources of revenue.

Outlook

We remain confident in our belief that high-quality companies with a capability for sustained long-term growth can outperform over time. Our portfolio positioning reflects where we are finding stocks of what we believe are attractive, well-run mature growth companies as a result of the application of that philosophy and process.

At the end of the reporting period, our largest sector overweight relative to the benchmark was communication services. The sector encompasses entertainment and communication stocks, including large portfolio holdings Facebook and Google parent Alphabet. Health care was the largest sector underweight. We view growth opportunities in the health care space as highly bifurcated. We have no exposure to life sciences tools and services and health care technology but are notably overweight in health care providers and services. Information technology ended the period underweight. However, information technology remains the largest sector allocation on an absolute basis, reflecting an abundance of what we view as high-quality, well-run companies benefiting from powerful secular trends.















6



Fund Characteristics
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Apple, Inc. 12.9%
Alphabet, Inc.* 9.2%
Amazon.com, Inc. 8.4%
Microsoft Corp. 6.2%
Mastercard, Inc., Class A 5.0%
PayPal Holdings, Inc. 4.5%
Facebook, Inc., Class A 4.4%
UnitedHealth Group, Inc. 3.9%
salesforce.com, Inc. 3.0%
Visa, Inc., Class A 2.2%
*Includes all classes of the issuer held by the fund.
Top Five Industries % of net assets
Software 14.3%
Interactive Media and Services 13.6%
Technology Hardware, Storage and Peripherals 12.9%
IT Services 12.0%
Internet and Direct Marketing Retail 8.4%
Types of Investments in Portfolio % of net assets
Common Stocks 99.2%
Convertible Bonds 0.7%
Rights
—*
Total Equity Exposure 99.9%
Temporary Cash Investments 0.1%
Other Assets and Liabilities
—*
*Category is less than 0.05% of total net assets.
7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

8




Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period
(1)
5/1/20 - 10/31/20
 
Annualized
Expense Ratio
(1)
Actual
Investor Class $1,000 $1,187.90 $5.33 0.97%
I Class $1,000 $1,189.20 $4.24 0.77%
Y Class $1,000 $1,190.10 $3.41 0.62%
A Class $1,000 $1,186.50 $6.71 1.22%
C Class $1,000 $1,181.90 $10.80 1.97%
R Class $1,000 $1,185.00 $8.07 1.47%
R5 Class $1,000 $1,189.20 $4.24 0.77%
R6 Class $1,000 $1,190.10 $3.41 0.62%
Hypothetical
Investor Class $1,000 $1,020.26 $4.93 0.97%
I Class $1,000 $1,021.27 $3.91 0.77%
Y Class $1,000 $1,022.02 $3.15 0.62%
A Class $1,000 $1,019.00 $6.19 1.22%
C Class $1,000 $1,015.23 $9.98 1.97%
R Class $1,000 $1,017.75 $7.46 1.47%
R5 Class $1,000 $1,021.27 $3.91 0.77%
R6 Class $1,000 $1,022.02 $3.15 0.62%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 99.2%
Aerospace and Defense — 0.7%
Mercury Systems, Inc.(1)
388,800  $ 26,780,544 
Auto Components — 0.4%
Aptiv plc 155,600  15,013,844 
Automobiles — 0.8%
Tesla, Inc.(1)
82,000  31,819,280 
Beverages — 0.9%
Constellation Brands, Inc., Class A 152,700  25,230,621 
Diageo plc 330,500  10,690,785 
35,921,406 
Biotechnology — 3.2%
Biogen, Inc.(1)
193,100  48,674,717 
Regeneron Pharmaceuticals, Inc.(1)
110,500  60,063,380 
Vertex Pharmaceuticals, Inc.(1)
70,500  14,689,380 
123,427,477 
Capital Markets — 1.4%
Moody's Corp. 71,100  18,692,190 
MSCI, Inc. 101,000  35,333,840 
54,026,030 
Chemicals — 0.7%
Sherwin-Williams Co. (The) 37,500  25,799,250 
Containers and Packaging — 1.2%
Ball Corp. 500,600  44,553,400 
Entertainment — 2.0%
Electronic Arts, Inc.(1)
394,300  47,248,969 
Walt Disney Co. (The) 238,300  28,893,875 
76,142,844 
Equity Real Estate Investment Trusts (REITs) — 2.7%
American Tower Corp. 208,600  47,904,990 
Equinix, Inc. 78,600  57,475,464 
105,380,454 
Food and Staples Retailing — 1.2%
Costco Wholesale Corp. 130,200  46,562,124 
Health Care Equipment and Supplies — 2.9%
Boston Scientific Corp.(1)
124,300  4,259,761 
Danaher Corp. 140,000  32,135,600 
Penumbra, Inc.(1)
129,300  33,751,179 
Stryker Corp. 212,800  42,987,728 
113,134,268 
Health Care Providers and Services — 3.9%
UnitedHealth Group, Inc. 497,600  151,837,664 
Industrial Conglomerates — 0.6%
Roper Technologies, Inc. 58,300  21,649,122 
Interactive Media and Services — 13.6%
Alphabet, Inc., Class A(1)
90,600  146,419,566 
Alphabet, Inc., Class C(1)
129,100  209,272,391 
10



Shares Value
Facebook, Inc., Class A(1)
647,600  $ 170,390,036 
526,081,993 
Internet and Direct Marketing Retail — 8.4%
Amazon.com, Inc.(1)
106,300  322,742,745 
IT Services — 11.7%
Mastercard, Inc., Class A 674,500  194,687,680 
PayPal Holdings, Inc.(1)
926,300  172,412,219 
Visa, Inc., Class A 459,900  83,568,429 
450,668,328 
Machinery — 0.6%
FANUC Corp. 115,300  24,507,092 
Personal Products — 0.8%
Estee Lauder Cos., Inc. (The), Class A 143,500  31,521,210 
Pharmaceuticals — 1.7%
Bristol-Myers Squibb Co. 1,109,200  64,832,740 
Professional Services — 3.1%
IHS Markit Ltd. 783,900  63,393,993 
Verisk Analytics, Inc. 312,100  55,544,437 
118,938,430 
Road and Rail — 0.4%
Canadian Pacific Railway Ltd. 56,800  16,973,919 
Semiconductors and Semiconductor Equipment — 4.5%
Analog Devices, Inc. 448,700  53,184,411 
KLA Corp. 70,100  13,822,318 
Maxim Integrated Products, Inc. 812,300  56,576,695 
Texas Instruments, Inc. 352,800  51,011,352 
174,594,776 
Software — 13.9%
Adobe, Inc.(1)
45,400  20,298,340 
Atlassian Corp. plc, Class A(1)
367,400  70,401,188 
Crowdstrike Holdings, Inc., Class A(1)
191,000  23,653,440 
Microsoft Corp. 1,181,100  239,137,317 
Proofpoint, Inc.(1)
165,000  15,797,100 
salesforce.com, Inc.(1)
504,600  117,203,442 
Zendesk, Inc.(1)
461,100  51,154,434 
537,645,261 
Specialty Retail — 3.4%
Home Depot, Inc. (The) 167,300  44,620,583 
Lowe's Cos., Inc. 307,800  48,663,180 
TJX Cos., Inc. (The) 718,500  36,499,800 
129,783,563 
Technology Hardware, Storage and Peripherals — 12.9%
Apple, Inc. 4,558,000  496,183,880 
Textiles, Apparel and Luxury Goods — 1.6%
NIKE, Inc., Class B 498,200  59,823,856 
TOTAL COMMON STOCKS
(Cost $1,426,828,655)
3,826,345,500 



11



Shares/Principal Amount Value
CONVERTIBLE BONDS — 0.7%
IT Services — 0.3%
Square, Inc., 0.50%, 5/15/23 $ 5,601,000  $ 11,595,131 
Software — 0.4%
PagerDuty, Inc., 1.25%, 7/1/25(2)
15,622,000  15,902,598 
TOTAL CONVERTIBLE BONDS
(Cost $20,694,718)
27,497,729 
RIGHTS
Pharmaceuticals
Bristol-Myers Squibb Co.(1)
(Cost $832,404)
390,800  1,274,008 
TEMPORARY CASH INVESTMENTS — 0.1%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $787,871), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $775,150) 775,146 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 3.625%, 2/15/44, valued at $1,376,046), at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $1,349,007) 1,349,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 89  89 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $2,124,235)
2,124,235 
TOTAL INVESTMENT SECURITIES — 100.0%
(Cost $1,450,480,012)
3,857,241,472 
OTHER ASSETS AND LIABILITIES
(372,196)
TOTAL NET ASSETS — 100.0% $ 3,856,869,276 

FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
CAD 661,209  USD 502,876  Morgan Stanley 12/31/20 $ (6,412)
USD 392,668  CAD 519,663  Morgan Stanley 12/31/20 2,483 
USD 367,616  CAD 486,662  Morgan Stanley 12/31/20 2,209 
USD 11,868,194  CAD 15,819,709  Morgan Stanley 12/31/20 (9,927)
$ (11,647)

NOTES TO SCHEDULE OF INVESTMENTS
CAD - Canadian Dollar
USD - United States Dollar
Category is less than 0.05% of total net assets.
(1)Non-income producing.
(2)Security was purchased pursuant to Rule 144A under the Securities Act of 1933 and may be sold in transactions exempt from registration, normally to qualified institutional investors. The aggregate value of these securities at the period end was $15,902,598, which represented 0.4% of total net assets.


See Notes to Financial Statements.
12



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $1,450,480,012) $ 3,857,241,472 
Receivable for investments sold 5,029,239 
Receivable for capital shares sold 671,593 
Unrealized appreciation on forward foreign currency exchange contracts 4,692 
Dividends and interest receivable 1,718,887 
3,864,665,883 
Liabilities
Payable for investments purchased 1,985,028
Payable for capital shares redeemed 2,489,286
Unrealized depreciation on forward foreign currency exchange contracts 16,339
Accrued management fees 3,287,357
Distribution and service fees payable 18,597
7,796,607
Net Assets $ 3,856,869,276 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 1,197,462,515 
Distributable earnings 2,659,406,761 
$ 3,856,869,276 

Net Assets Shares Outstanding Net Asset Value Per Share
Investor Class, $0.01 Par Value $3,596,722,207 38,289,617 $93.93
I Class, $0.01 Par Value $119,954,185 1,249,629 $95.99
Y Class, $0.01 Par Value $72,595,149 753,979 $96.28
A Class, $0.01 Par Value $54,557,816 598,324 $91.18*
C Class, $0.01 Par Value $5,390,335 68,036 $79.23
R Class, $0.01 Par Value $3,384,358 37,662 $89.86
R5 Class, $0.01 Par Value $9,215 96 $95.99
R6 Class, $0.01 Par Value $4,256,011 44,258 $96.16
*Maximum offering price $96.74 (net asset value divided by 0.9425).


See Notes to Financial Statements.
13



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $60,352) $ 29,204,115 
Interest 220,450 
Securities Lending, net 53,994 
29,478,559 
Expenses:
Management fees 34,999,463 
Distribution and service fees:
A Class 124,929 
C Class 56,881 
R Class 16,762 
Directors' fees and expenses 114,845 
Other expenses 1,091 
35,313,971 
Fees waived(1)
(716,482)
34,597,489 
Net investment income (loss) (5,118,930)
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 267,330,014 
Forward foreign currency exchange contract transactions 163,865 
Written options contract transactions 888,402 
Foreign currency translation transactions (40,312)
268,341,969 
Change in net unrealized appreciation (depreciation) on:
Investments 557,295,358 
Forward foreign currency exchange contracts 84,581 
Written options contracts (20,820)
Translation of assets and liabilities in foreign currencies 1,194 
557,360,313 
Net realized and unrealized gain (loss) 825,702,282 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 820,583,352 

(1)Amount consists of $668,866, $22,847, $12,216, $9,994, $1,138, $670, $1 and $750 for Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class, respectively.


See Notes to Financial Statements.
14



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ (5,118,930) $ 20,145 
Net realized gain (loss) 268,341,969  179,904,572 
Change in net unrealized appreciation (depreciation) 557,360,313  274,093,557 
Net increase (decrease) in net assets resulting from operations 820,583,352  454,018,274 
Distributions to Shareholders
From earnings:
Investor Class (167,944,066) (213,120,945)
I Class (5,704,618) (5,385,005)
Y Class (2,611,966) (1,027,005)
A Class (2,383,411) (3,006,841)
C Class (346,331) (473,987)
R Class (178,475) (180,464)
R5 Class (394) (476)
R6 Class (158,543) (145,270)
Decrease in net assets from distributions (179,327,804) (223,339,993)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) (42,842,237) 57,161,383 
Net increase (decrease) in net assets 598,413,311  287,839,664 
Net Assets
Beginning of period 3,258,455,965  2,970,616,301 
End of period $ 3,856,869,276  $ 3,258,455,965 


See Notes to Financial Statements.
15



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Select Fund (the fund) is one fund in a series issued by the corporation. The fund’s investment objective is to seek long-term capital growth.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class and R6 Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.

Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.

Fixed income securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. Convertible bonds are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information.

Open-end management investment companies are valued at the reported net asset value per share. Exchange-traded options contracts are valued at a mean as provided by independent pricing services. Repurchase agreements are valued at cost, which approximates fair value. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.


16



If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.

The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

17



Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.
Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.
Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.

Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC.
Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of
funds (such as subadvised funds and separate accounts) that use very similar investment teams and
18



strategies (strategy assets). During the period ended October 31, 2020, the investment advisor agreed to waive 0.02% of the fund's management fee. The investment advisor expects this waiver to continue until July 31, 2021 and cannot terminate it prior to such date without the approval of the Board of Directors.

The management fee schedule range and the effective annual management fee before and after waiver for each class for the period ended October 31, 2020 are as follows:
Management Fee
Effective Annual Management Fee
Schedule Range
Before Waiver
After Waiver
Investor Class 0.800% to 0.990% 0.99% 0.97%
I Class 0.600% to 0.790% 0.79% 0.77%
Y Class 0.450% to 0.640% 0.64% 0.62%
A Class 0.800% to 0.990% 0.99% 0.97%
C Class 0.800% to 0.990% 0.99% 0.97%
R Class 0.800% to 0.990% 0.99% 0.97%
R5 Class 0.600% to 0.790% 0.79% 0.77%
R6 Class 0.450% to 0.640% 0.64% 0.62%

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.

Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.
Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $21,891 and $4,001,132, respectively. The effect of interfund transactions on the Statement of Operations was $730,243 in net realized gain (loss) on investment transactions.
4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments, for the period ended October 31, 2020 were $576,208,800 and $778,268,797, respectively.

19



5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019
Shares Amount Shares Amount
Investor Class/Shares Authorized 475,000,000  475,000,000 
Sold 1,243,588  $ 102,506,141  800,738  $ 57,669,376 
Issued in reinvestment of distributions 2,018,516  159,826,128  3,227,630  203,857,091 
Redeemed (3,836,882) (319,224,605) (3,621,970) (261,065,622)
(574,778) (56,892,336) 406,398  460,845 
I Class/Shares Authorized 40,000,000  40,000,000 
Sold 263,810  22,646,467  647,839  49,485,276 
Issued in reinvestment of distributions 67,528  5,454,233  78,144  5,019,942 
Redeemed (397,122) (32,507,442) (356,766) (26,327,849)
(65,784) (4,406,742) 369,217  28,177,369 
Y Class/Shares Authorized 30,000,000  30,000,000 
Sold 372,810  32,358,265  431,529  32,202,180 
Issued in reinvestment of distributions 31,872  2,578,781  15,293  982,580 
Redeemed (224,881) (20,117,689) (66,043) (4,978,500)
179,801  14,819,357  380,779  28,206,260 
A Class/Shares Authorized 40,000,000  40,000,000 
Sold 150,187  12,354,119  60,310  4,251,171 
Issued in reinvestment of distributions 30,503  2,349,653  48,212  2,974,205 
Redeemed (130,967) (10,805,132) (106,841) (7,576,575)
49,723  3,898,640  1,681  (351,199)
C Class/Shares Authorized 30,000,000  30,000,000 
Sold 3,306  218,808  9,195  550,593 
Issued in reinvestment of distributions 4,778  321,908  8,020  439,266 
Redeemed (21,797) (1,593,266) (23,445) (1,502,183)
(13,713) (1,052,550) (6,230) (512,324)
R Class/Shares Authorized 30,000,000  30,000,000 
Sold 13,166  1,067,191  11,175  787,619 
Issued in reinvestment of distributions 2,346  178,475  2,952  180,464 
Redeemed (17,732) (1,462,813) (5,809) (414,285)
(2,220) (217,147) 8,318  553,798 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Issued in reinvestment of distributions 394  476 
R6 Class/Shares Authorized 40,000,000  40,000,000 
Sold 24,479  2,048,036  12,413  902,406 
Issued in reinvestment of distributions 1,952  157,710  2,252  144,508 
Redeemed (13,941) (1,197,599) (5,652) (420,756)
12,490  1,008,147  9,013  626,158 
Net increase (decrease) (414,476) $ (42,842,237) 1,169,184  $ 57,161,383 

20



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 3,774,173,704  $ 52,171,796  — 
Convertible Bonds —  27,497,729  — 
Rights 1,274,008  —  — 
Temporary Cash Investments 89  2,124,146  — 
$ 3,775,447,801  $ 81,793,671  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 4,692  — 
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 16,339  — 

21



7. Derivative Instruments

Equity Price Risk — The fund is subject to equity price risk in the normal course of pursuing its investment objectives. A fund may enter into options contracts based on an equity index or specific security in order to manage its exposure to changes in market conditions. The risks of entering into equity price risk derivative instruments include the possible lack of liquidity, failure of the counterparty to meet its obligations, and that there may be unfavorable changes in the underlying investments or instruments. A fund may purchase or write an option contract to protect against declines in market value on the underlying index or security. A purchased option contract provides the fund a right, but not an obligation, to buy (call) or sell (put) an equity-related asset at a specified exercise price within a certain period or on a specific date. A written option contract holds the corresponding obligation to sell (call writing) or buy (put writing) the underlying equity-related asset if the purchaser exercises the option contract. The buyer pays the seller an initial purchase price (premium) for this right. Option contracts purchased by a fund are accounted for in the same manner as marketable portfolio securities. The premium received by a fund for option contracts written is recorded as a liability and valued daily. The proceeds from securities sold through the exercise of option contracts are decreased by the premium paid to purchase the option contracts. A fund may recognize a realized gain or loss when the option contract is closed, exercised or expires. Net realized and unrealized gains or losses occurring during the holding period of purchased options contracts are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively. Net realized and unrealized gains or losses occurring during the holding period of written options contracts are a component of net realized gain (loss) on written options contract transactions and change in net unrealized appreciation (depreciation) on written options contracts, respectively. The fund’s average exposure to equity price risk derivative instruments held during the period was 713 written options contracts.
Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $18,219,002.

Value of Derivative Instruments as of October 31, 2020
Asset Derivatives
Liability Derivatives
Type of Risk Exposure Location on Statement of Assets and Liabilities
Value
Location on Statement of Assets and Liabilities
Value
Foreign Currency Risk Unrealized appreciation on forward foreign currency exchange contracts $ 4,692  Unrealized depreciation on forward foreign currency exchange contracts $ 16,339 

22



Effect of Derivative Instruments on the Statement of Operations for the Year Ended October 31, 2020
Net Realized Gain (Loss)
Change in Net Unrealized
Appreciation (Depreciation)
Type of Risk Exposure Location on Statement of Operations
Value
Location on Statement of Operations
Value
Equity Price Risk Net realized gain (loss) on written options contract transactions $ 888,402  Change in net unrealized appreciation (depreciation) on written options contracts $ (20,820)
Foreign Currency Risk Net realized gain (loss) on forward foreign currency exchange contract transactions 163,865  Change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts 84,581 
$ 1,052,267  $ 63,761 

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

9. Federal Tax Information

On December 8, 2020, the fund declared and paid a per-share distribution from net realized gains to
shareholders of record on December 7, 2020 of $6.3212 for the Investor Class, I Class, Y Class, A Class,
C Class, R Class, R5 Class and R6 Class.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 28,200  $ 1,537,114 
Long-term capital gains $ 179,299,604  $ 221,802,879 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:
Federal tax cost of investments $ 1,450,515,454 
Gross tax appreciation of investments $ 2,421,591,472 
Gross tax depreciation of investments (14,865,454)
Net tax appreciation (depreciation) of investments 2,406,726,018 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 1,136 
Net tax appreciation (depreciation) $ 2,406,727,154 
Undistributed ordinary income $ — 
Accumulated long-term gains $ 257,590,403 
Late-year ordinary loss deferral $ (4,910,796)
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.

Loss deferrals represent certain qualified losses that the fund has elected to treat as having been incurred in the following fiscal year for federal income tax purposes.
23



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $78.58 (0.13) 19.83 19.70 (4.35) (4.35) $93.93 26.10% 0.97% 0.99% (0.15)% (0.17)% 16% $3,596,722 
2019 $73.74
(3)
10.42 10.42 (0.03) (5.55) (5.58) $78.58 15.98% 0.97% 0.99%
0.00%(4)
(0.02)% 17% $3,054,007 
2018 $71.92 0.04 6.20 6.24 (0.21) (4.21) (4.42) $73.74 8.94% 0.97% 0.99% 0.06% 0.04% 22% $2,835,970 
2017 $58.32 0.21 15.59 15.80 (0.22) (1.98) (2.20) $71.92 27.93% 0.99% 1.00% 0.33% 0.32% 19% $2,753,729 
2016 $61.57 0.20 0.30 0.50 (0.25) (3.50) (3.75) $58.32 0.98% 0.99% 0.99% 0.36% 0.36% 16% $2,287,797 
I Class
2020 $80.06 0.05 20.23 20.28 (4.35) (4.35) $95.99 26.35% 0.77% 0.79% 0.05% 0.03% 16% $119,954 
2019 $75.02 0.13 10.63 10.76 (0.17) (5.55) (5.72) $80.06 16.22% 0.77% 0.79% 0.20% 0.18% 17% $105,310 
2018 $73.11 0.19 6.29 6.48 (0.36) (4.21) (4.57) $75.02 9.15% 0.77% 0.79% 0.26% 0.24% 22% $70,986 
2017 $59.25 0.31 15.87 16.18 (0.34) (1.98) (2.32) $73.11 28.20% 0.79% 0.80% 0.53% 0.52% 19% $60,895 
2016 $62.49 0.32 0.31 0.63 (0.37) (3.50) (3.87) $59.25 1.19% 0.79% 0.79% 0.56% 0.56% 16% $28,061 
Y Class
2020 $80.17 0.16 20.30 20.46 (4.35) (4.35) $96.28 26.55% 0.62% 0.64% 0.20% 0.18% 16% $72,595 
2019 $75.13 0.22 10.64 10.86 (0.27) (5.55) (5.82) $80.17 16.38% 0.62% 0.64% 0.35% 0.33% 17% $46,034 
2018 $73.13 0.28 6.33 6.61 (0.40) (4.21) (4.61) $75.13 9.34% 0.62% 0.64% 0.41% 0.39% 22% $14,529 
2017(5)
$63.80 0.22 9.11 9.33 $73.13 14.62%
0.64%(6)
0.65%(6)
0.59%(6)
0.58%(6)
19%(7)
$6 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
A Class
2020 $76.58 (0.33) 19.28 18.95 (4.35) (4.35) $91.18 25.79% 1.22% 1.24% (0.40)% (0.42)% 16% $54,558 
2019 $72.15 (0.18) 10.16 9.98 (5.55) (5.55) $76.58 15.69% 1.22% 1.24% (0.25)% (0.27)% 17% $42,013 
2018 $70.45 (0.14) 6.07 5.93 (0.02) (4.21) (4.23) $72.15 8.67% 1.22% 1.24% (0.19)% (0.21)% 22% $39,459 
2017 $57.16 0.05 15.29 15.34 (0.07) (1.98) (2.05) $70.45 27.63% 1.24% 1.25% 0.08% 0.07% 19% $40,345 
2016 $60.41 0.06 0.29 0.35 (0.10) (3.50) (3.60) $57.16 0.73% 1.24% 1.24% 0.11% 0.11% 16% $36,723 
C Class
2020 $67.55 (0.82) 16.85 16.03 (4.35) (4.35) $79.23 24.85% 1.97% 1.99% (1.15)% (1.17)% 16% $5,390 
2019 $64.79 (0.63) 8.94 8.31 (5.55) (5.55) $67.55 14.82% 1.97% 1.99% (1.00)% (1.02)% 17% $5,523 
2018 $64.11 (0.62) 5.51 4.89 (4.21) (4.21) $64.79 7.86% 1.97% 1.99% (0.94)% (0.96)% 22% $5,700 
2017 $52.51 (0.39) 13.97 13.58 (1.98) (1.98) $64.11 26.66% 1.99% 2.00% (0.67)% (0.68)% 19% $5,668 
2016 $56.09 (0.33) 0.25 (0.08) (3.50) (3.50) $52.51 (0.02)% 1.99% 1.99% (0.64)% (0.64)% 16% $4,570 
R Class
2020 $75.71 (0.53) 19.03 18.50 (4.35) (4.35) $89.86 25.48% 1.47% 1.49% (0.65)% (0.67)% 16% $3,384 
2019 $71.56 (0.36) 10.06 9.70 (5.55) (5.55) $75.71 15.40% 1.47% 1.49% (0.50)% (0.52)% 17% $3,019 
2018 $70.05 (0.30) 6.02 5.72 (4.21) (4.21) $71.56 8.41% 1.47% 1.49% (0.44)% (0.46)% 22% $2,259 
2017 $56.92 (0.11) 15.22 15.11 (1.98) (1.98) $70.05 27.30% 1.49% 1.50% (0.17)% (0.18)% 19% $3,518 
2016 $60.21 (0.08) 0.29 0.21 (3.50) (3.50) $56.92 0.49% 1.49% 1.49% (0.14)% (0.14)% 16% $2,814 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R5 Class
2020 $80.07 0.03 20.24 20.27 (4.35) (4.35) $95.99 26.34% 0.77% 0.79% 0.05% 0.03% 16% $9 
2019 $75.04 0.13 10.62 10.75 (0.17) (5.55) (5.72) $80.07 16.20% 0.77% 0.79% 0.20% 0.18% 17% $7 
2018 $73.10 0.18 6.28 6.46 (0.31) (4.21) (4.52) $75.04 9.13% 0.77% 0.79% 0.26% 0.24% 22% $6 
2017(5)
$63.83 0.17 9.10 9.27 $73.10 14.52%
0.79%(6)
0.80%(6)
0.44%(6)
0.43%(6)
19%(7)
$6 
R6 Class
2020 $80.08 0.16 20.27 20.43 (4.35) (4.35) $96.16 26.54% 0.62% 0.64% 0.20% 0.18% 16% $4,256 
2019 $75.05 0.25 10.60 10.85 (0.27) (5.55) (5.82) $80.08 16.39% 0.62% 0.64% 0.35% 0.33% 17% $2,544 
2018 $73.13 0.31 6.29 6.60 (0.47) (4.21) (4.68) $75.05 9.33% 0.62% 0.64% 0.41% 0.39% 22% $1,708 
2017 $59.27 0.51 15.76 16.27 (0.43) (1.98) (2.41) $73.13 28.38% 0.64% 0.65% 0.68% 0.67% 19% $1,519 
2016 $62.51 0.41 0.31 0.72 (0.46) (3.50) (3.96) $59.27 1.35% 0.64% 0.64% 0.71% 0.71% 16% $7,959 




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)Amount is less than $0.005.
(4)Ratio was less than 0.005%.
(5)April 10, 2017 (commencement of sale) through October 31, 2017.
(6)Annualized.
(7)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Select Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Select Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.
28



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
29



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
30



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





31



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
32



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one- and five-year periods and below its benchmark for the three- and ten-year periods reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
33



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was above the median of the total expense ratios of the Fund’s peer expense universe
34



and was within the range of its peer expense group. The Board and the Advisor agreed to a temporary reduction of the Fund's annual unified management fee of 0.02% (e.g., the Investor Class unified fee will be reduced from 0.99% to 0.97%) for at least one year, beginning August 1, 2020. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
35



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



36



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $28,200, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $189,757,172, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $10,457,568 distributed to shareholders on redemption of shares as part of the dividends paid deduction ( tax equalization).
37



Notes
38



Notes
39



Notes



40








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
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Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90969 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Small Cap Growth Fund
Investor Class (ANOIX)
I Class (ANONX)
Y Class (ANOYX)
A Class (ANOAX)
C Class (ANOCX)
R Class (ANORX)
R5 Class (ANOGX)
R6 Class (ANODX)
G Class (ANOHX)














Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
 
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
15
Statement of Operations
16
Statement of Changes in Net Assets
17
Notes to Financial Statements
18
Financial Highlights
25
Report of Independent Registered Public Accounting Firm
29
Management
30
Approval of Management Agreement
33
Additional Information
37

















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
 
Total Returns as of October 31, 2020
      Average Annual Returns  
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class ANOIX 32.43% 16.59% 14.23% 6/1/01
Russell 2000 Growth Index 13.37% 10.35% 11.94%
I Class ANONX 32.76% 16.83% 14.46% 5/18/07
Y Class ANOYX 32.96% 19.84% 4/10/17
A Class ANOAX 1/31/03
No sales charge 32.14% 16.30% 13.96%
With sales charge 24.51% 14.93% 13.28%
C Class ANOCX 31.18% 15.45% 13.09% 1/31/03
R Class ANORX 31.80% 16.02% 13.67% 9/28/07
R5 Class ANOGX 32.74% 19.66% 4/10/17
R6 Class ANODX 32.91% 17.01% 13.91% 7/26/13
G Class ANOHX 34.09% 24.23% 4/1/19
Average annual returns since inception are presented when ten years of performance history is not available.
G Class returns would have been lower if a portion of the fees had not been waived. Extraordinary performance is attributable in part to unusually favorable market conditions and may not be repeated or consistently achieved in the future.

Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.














Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-0CDC1DEDBDF34EB08061.JPG
Value on October 31, 2020
Investor Class — $37,879
Russell 2000 Growth Index — $30,922

Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class G Class
1.28% 1.08% 0.93% 1.53% 2.28% 1.78% 1.08% 0.93% 0.93%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.












Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary
 
Portfolio Managers: Jackie Wagner and Jeff Hoernemann

Performance Summary

Small Cap Growth returned 32.43%* for the 12 months ended October 31, 2020, outpacing the 13.37% return of the fund’s benchmark, the Russell 2000 Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell 2000 Growth Index, health care stocks posted the best returns, followed by information technology and consumer discretionary. Energy stocks registered significant losses as the price of oil declined amid falling demand.

Stock choices within the health care and information technology sectors helped drive outperformance relative to the benchmark. Stock selection in the consumer staples and energy sectors detracted.

Health Care Stocks Benefited Performance

Stock selection across health care industries was helpful, led by biotechnology and pharmaceuticals. Immunomedics was a top contributor. The biopharmaceutical company agreed to be acquired by Gilead Sciences, reflecting the value of its oncology program, which has multiple potential further indications. The holding was eliminated as a result of the deal. Early in the year, Teladoc Health, the top provider of telehealth services, reported results and guidance ahead of expectations. As the pandemic took hold, the company saw rapidly accelerating demand for its services as providers sought out socially distanced care. Catalent, a contract manufacturer of pharmaceutical and biologic products, was another top contributor in the health care sector. We sold our holdings of Teladoc and Catalent as their capitalization sizes grew beyond the fund’s small-cap parameters.

Other significant contributors included Chegg. This provider of products and services to students continued to post better-than-expected results. The company benefited from strong subscription growth, operating expense leverage and from its acquisition of Thinkful. The acceleration of at-home/online learning due to COVID-19 boosted adoption trends and allowed the company to capitalize on cross-selling opportunities. Palomar Holdings helped performance. This property and casualty insurance company is mostly exposed to earthquakes and other catastrophes such as wind and flood. Gross written premium growth remained strong, driven by demand for quake insurance. Pricing growth also accelerated.

As a small-cap fund, we occasionally invest in initial public offerings (IPOs). During the period, our IPOs were modest positive contributors.

Consumer Staples Weighed on Performance

Stock selection among personal products companies and an underweight allocation to the industry led relative underperformance in the consumer staples sector. Underweighting beverages stocks also hampered performance. Meal replacement company Medifast underperformed. Margins and
margin guidance for the company did not meet lofty expectations over several quarters. The company also significantly missed expectations for forward guidance. We eliminated the holding.


*All fund returns referenced in this commentary are for Investor Class shares. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.
5



Stock choices in the energy sector detracted. Callon Petroleum, an energy exploration and production company, was severely impacted by plummeting crude oil prices. Demand destruction driven by strict social distancing policies implemented around the world as the coronavirus spread was exacerbated by an oil price war that led to an oil glut. We eliminated our holding.

Other significant detractors included Everbridge, a provider of software applications that automate the delivery of critical information to help keep people safe and businesses running. Although Everbridge posted strong results, billings came up short of expectations. Not owning benchmark component Quidel detracted as the diagnostics equipment and test maker won approval for a point-of-care coronavirus antigen test. The Brink’s Co.’s cash management business was significantly impacted by retail and restaurant closures due to pandemic concerns. Its Latin America exposure put the company in a position of slower recovery relative to European and U.S. companies. Although Essential Properties Realty Trust’s results were in line with expectations and the company reaffirmed its guidance for the year, the stock underperformed due to the quality of the company’s end customers, which leaves it exposed to lower-quality properties. The holding was eliminated.

Outlook

Small Cap Growth’s investment process focuses on smaller companies with accelerating growth rates and share-price momentum. We believe that active investments in such companies will generate outperformance over time compared with the Russell 2000 Growth Index.

The portfolio positioning remains largely stock specific, with few thematic trends. As of October 31, 2020, financials was the largest overweight sector relative to the benchmark. Health care was the largest underweight sector.



6



Fund Characteristics
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Chegg, Inc. 1.6%
Natera, Inc. 1.4%
R1 RCM, Inc. 1.4%
NMI Holdings, Inc., Class A 1.3%
Crocs, Inc. 1.3%
FirstService Corp. 1.3%
Five9, Inc. 1.3%
National Vision Holdings, Inc. 1.2%
Churchill Downs, Inc. 1.2%
Envestnet, Inc. 1.2%
Top Five Industries % of net assets
Biotechnology 16.9%
Software 9.3%
Health Care Providers and Services 5.9%
Health Care Equipment and Supplies 4.6%
Semiconductors and Semiconductor Equipment 4.5%
Types of Investments in Portfolio % of net assets
Common Stocks 98.1%
Temporary Cash Investments 2.3%
Temporary Cash Investments - Securities Lending Collateral 1.2%
Other Assets and Liabilities (1.6)%

7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.


8



Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
Investor Class $1,000 $1,322.10 $7.06 1.21%
I Class $1,000 $1,324.00 $5.90 1.01%
Y Class $1,000 $1,325.30 $5.03 0.86%
A Class $1,000 $1,320.80 $8.52 1.46%
C Class $1,000 $1,315.70 $12.86 2.21%
R Class $1,000 $1,319.00 $9.97 1.71%
R5 Class $1,000 $1,323.80 $5.90 1.01%
R6 Class $1,000 $1,324.70 $5.03 0.86%
G Class $1,000 $1,330.50 $0.06 0.01%
Hypothetical
Investor Class $1,000 $1,019.05 $6.14 1.21%
I Class $1,000 $1,020.06 $5.13 1.01%
Y Class $1,000 $1,020.81 $4.37 0.86%
A Class $1,000 $1,017.80 $7.41 1.46%
C Class $1,000 $1,014.03 $11.19 2.21%
R Class $1,000 $1,016.54 $8.67 1.71%
R5 Class $1,000 $1,020.06 $5.13 1.01%
R6 Class $1,000 $1,020.81 $4.37 0.86%
G Class $1,000 $1,025.09 $0.05 0.01%
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 98.1%
Aerospace and Defense — 2.9%
AAR Corp. 142,398  $ 2,771,065 
Aerojet Rocketdyne Holdings, Inc.(1)
439,475  14,247,780 
CAE, Inc. 530,316  9,063,496 
Kratos Defense & Security Solutions, Inc.(1)
745,651  14,085,347 
Mercury Systems, Inc.(1)
59,196  4,077,420 
44,245,108 
Airlines — 0.7%
Alaska Air Group, Inc. 263,219  9,973,368 
Auto Components — 1.1%
LCI Industries 151,007  16,559,428 
Biotechnology — 16.9%
ACADIA Pharmaceuticals, Inc.(1)
213,458  9,915,124 
Acceleron Pharma, Inc.(1)
108,667  11,364,395 
ADC Therapeutics SA(1)
315,020  9,037,924 
Amarin Corp. plc, ADR(1)(2)
285,179  1,385,970 
Amicus Therapeutics, Inc.(1)
745,416  13,290,767 
Arcutis Biotherapeutics, Inc.(1)
279,196  4,975,273 
Arena Pharmaceuticals, Inc.(1)
112,789  9,668,273 
Biohaven Pharmaceutical Holding Co. Ltd.(1)
174,156  13,490,124 
Blueprint Medicines Corp.(1)
146,710  15,005,499 
Bridgebio Pharma, Inc.(1)(2)
233,920  8,977,850 
ChemoCentryx, Inc.(1)
156,220  7,498,560 
Deciphera Pharmaceuticals, Inc.(1)
201,845  11,721,139 
FibroGen, Inc.(1)
263,014  10,094,477 
Flexion Therapeutics, Inc.(1)
617,459  7,403,333 
Generation Bio Co.(1)
114,551  2,959,998 
Global Blood Therapeutics, Inc.(1)
117,516  6,214,246 
Halozyme Therapeutics, Inc.(1)
400,950  11,226,600 
Heron Therapeutics, Inc.(1)
291,597  4,755,947 
Insmed, Inc.(1)
454,820  14,981,771 
Iovance Biotherapeutics, Inc.(1)
116,322  4,150,369 
Karuna Therapeutics, Inc.(1)
129,982  10,553,238 
Kymera Therapeutics, Inc.(1)
140,480  5,055,875 
Mirati Therapeutics, Inc.(1)
56,590  12,287,953 
Natera, Inc.(1)
320,496  21,556,561 
Relay Therapeutics, Inc.(1)
114,648  4,235,097 
Ultragenyx Pharmaceutical, Inc.(1)
137,824  13,851,312 
Viela Bio, Inc.(1)(2)
245,830  7,844,435 
253,502,110 
Building Products — 3.2%
American Woodmark Corp.(1)
106,641  8,809,613 
Builders FirstSource, Inc.(1)
442,408  13,404,963 
Masonite International Corp.(1)
164,584  14,483,392 
Trex Co., Inc.(1)
164,360  11,429,594 
48,127,562 
10



Shares Value
Capital Markets — 1.6%
Hamilton Lane, Inc., Class A 246,429  $ 17,176,101 
TMX Group Ltd. 67,513  6,560,259 
23,736,360 
Chemicals — 0.6%
H.B. Fuller Co. 185,285  8,384,146 
Commercial Services and Supplies — 1.8%
Brink's Co. (The) 335,355  14,363,254 
Clean Harbors, Inc.(1)
247,978  13,135,395 
27,498,649 
Communications Equipment — 0.2%
Lumentum Holdings, Inc.(1)
39,080  3,231,525 
Construction Materials — 0.6%
Summit Materials, Inc., Class A(1)
472,834  8,364,433 
Containers and Packaging — 0.9%
Berry Global Group, Inc.(1)
276,526  12,894,407 
Diversified Consumer Services — 1.6%
Chegg, Inc.(1)
322,632  23,694,094 
Electrical Equipment — 1.0%
Array Technologies, Inc.(1)
174,373  6,425,645 
Sensata Technologies Holding plc(1)
192,820  8,428,162 
14,853,807 
Electronic Equipment, Instruments and Components — 2.8%
Jabil, Inc. 324,134  10,741,801 
Littelfuse, Inc. 81,856  16,202,577 
nLight, Inc.(1)
161,792  3,436,462 
SYNNEX Corp. 90,144  11,866,556 
42,247,396 
Equity Real Estate Investment Trusts (REITs) — 1.4%
Global Medical REIT, Inc. 857,701  10,661,224 
Innovative Industrial Properties, Inc. 47,061  5,488,724 
Rexford Industrial Realty, Inc. 108,345  5,033,709 
21,183,657 
Food and Staples Retailing — 1.0%
Grocery Outlet Holding Corp.(1)
219,284  9,652,882 
Sprouts Farmers Market, Inc.(1)
297,119  5,660,117 
15,312,999 
Food Products — 0.6%
Whole Earth Brands, Inc.(1)
1,147,541  9,398,361 
Health Care Equipment and Supplies — 4.6%
Acutus Medical, Inc.(1)
280,759  6,420,958 
Eargo, Inc.(1)
191,445  6,633,569 
Globus Medical, Inc., Class A(1)
196,751  10,254,662 
ICU Medical, Inc.(1)
55,612  9,887,258 
Inari Medical, Inc.(1)
36,410  2,410,342 
OrthoPediatrics Corp.(1)
141,358  6,304,567 
Silk Road Medical, Inc.(1)
248,828  15,078,977 
Tandem Diabetes Care, Inc.(1)
113,883  12,413,247 
69,403,580 
Health Care Providers and Services — 5.9%
Acadia Healthcare Co., Inc.(1)
249,040  8,878,276 
AMN Healthcare Services, Inc.(1)
205,132  13,391,017 
11



Shares Value
Encompass Health Corp. 196,606  $ 12,053,914 
HealthEquity, Inc.(1)
273,264  14,070,363 
Option Care Health, Inc.(1)
883,354  11,775,109 
R1 RCM, Inc.(1)
1,173,476  21,028,690 
RadNet, Inc.(1)
470,349  6,824,764 
88,022,133 
Health Care Technology — 1.4%
Health Catalyst, Inc.(1)(2)
397,607  13,709,489 
Phreesia, Inc.(1)
191,687  7,086,669 
20,796,158 
Hotels, Restaurants and Leisure — 3.5%
Brinker International, Inc. 322,002  14,019,967 
Churchill Downs, Inc. 118,829  17,723,345 
Planet Fitness, Inc., Class A(1)
144,683  8,575,362 
Wingstop, Inc. 100,394  11,678,834 
51,997,508 
Household Durables — 1.1%
TopBuild Corp.(1)
113,251  17,351,186 
Household Products — 0.6%
Reynolds Consumer Products, Inc. 312,786  8,833,077 
Independent Power and Renewable Electricity Producers — 0.6%
Innergex Renewable Energy, Inc. 500,660  9,026,385 
Insurance — 4.5%
BRP Group, Inc., Class A(1)
611,630  15,596,565 
eHealth, Inc.(1)
198,314  13,308,853 
Goosehead Insurance, Inc., Class A 114,199  13,993,945 
Kinsale Capital Group, Inc. 65,348  12,250,790 
Lemonade, Inc.(1)(2)
113,328  5,699,265 
Palomar Holdings, Inc.(1)
68,897  6,143,545 
66,992,963 
Interactive Media and Services — 1.1%
EverQuote, Inc., Class A(1)
231,963  7,768,441 
QuinStreet, Inc.(1)
573,226  9,174,482 
16,942,923 
Internet and Direct Marketing Retail — 0.2%
Leslie's, Inc.(1)
109,652  2,409,054 
IT Services — 3.4%
Globant SA(1)
64,396  11,630,562 
I3 Verticals, Inc., Class A(1)
607,754  12,537,965 
Nuvei Corp.(1)
247,858  9,210,403 
Repay Holdings Corp.(1)
775,009  17,460,953 
50,839,883 
Leisure Products — 1.5%
Brunswick Corp. 217,089  13,830,740 
Callaway Golf Co. 522,716  8,096,871 
21,927,611 
Life Sciences Tools and Services — 1.9%
NeoGenomics, Inc.(1)
396,643  15,560,305 
PRA Health Sciences, Inc.(1)
139,436  13,586,644 
29,146,949 
Machinery — 2.1%
Evoqua Water Technologies Corp.(1)
717,096  16,443,011 
12



Shares Value
Navistar International Corp.(1)
342,085  $ 14,747,285 
31,190,296 
Mortgage Real Estate Investment Trusts (REITs) — 0.7%
Hannon Armstrong Sustainable Infrastructure Capital, Inc. 236,204  9,885,137 
Personal Products — 0.4%
elf Beauty, Inc.(1)
302,236  6,126,324 
Pharmaceuticals — 1.8%
Axsome Therapeutics, Inc.(1)
123,801  8,209,244 
Harmony Biosciences Holdings, Inc.(1)
109,908  4,275,421 
Horizon Therapeutics plc(1)
129,311  9,689,273 
Optinose, Inc.(1)(2)
264,670  846,944 
Reata Pharmaceuticals, Inc., Class A(1)
31,811  3,712,662 
26,733,544 
Professional Services — 1.1%
ASGN, Inc.(1)
133,497  8,901,580 
Korn Ferry 253,378  7,649,482 
16,551,062 
Real Estate Management and Development — 2.7%
Altus Group Ltd. 164,309  6,722,573 
FirstService Corp. 144,165  19,331,289 
Redfin Corp.(1)
341,031  14,244,865 
40,298,727 
Semiconductors and Semiconductor Equipment — 4.5%
Allegro MicroSystems, Inc.(1)
195,969  3,586,233 
Entegris, Inc. 75,653  5,656,575 
Inphi Corp.(1)
26,450  3,696,652 
MKS Instruments, Inc. 69,728  7,557,818 
PDF Solutions, Inc.(1)
414,254  7,763,120 
Power Integrations, Inc. 256,180  15,424,598 
Semtech Corp.(1)
307,135  16,858,640 
SiTime Corp.(1)
91,817  7,665,801 
68,209,437 
Software — 9.3%
Envestnet, Inc.(1)
227,912  17,489,967 
Everbridge, Inc.(1)
107,792  11,284,744 
Five9, Inc.(1)
124,919  18,952,711 
Manhattan Associates, Inc.(1)
143,133  12,237,871 
Model N, Inc.(1)
434,622  15,311,733 
nCino, Inc.(1)
205,607  14,499,406 
Paylocity Holding Corp.(1)
66,783  12,389,582 
Rapid7, Inc.(1)
155,172  9,609,802 
RealPage, Inc.(1)
203,845  11,352,128 
SailPoint Technologies Holdings, Inc.(1)
358,376  14,876,188 
Vertex, Inc., Class A(1)
86,407  2,094,506 
140,098,638 
Specialty Retail — 2.8%
Lithia Motors, Inc., Class A 69,291  15,907,135 
National Vision Holdings, Inc.(1)
442,466  17,844,653 
Vroom, Inc.(1)
200,229  8,229,412 
41,981,200 
Textiles, Apparel and Luxury Goods — 1.3%
Crocs, Inc.(1)
376,644  19,709,780 
13



Shares Value
Thrifts and Mortgage Finance — 1.3%
NMI Holdings, Inc., Class A(1)
927,816  $ 19,938,766 
Trading Companies and Distributors — 0.9%
Applied Industrial Technologies, Inc. 231,395  14,126,665 
TOTAL COMMON STOCKS
(Cost $1,183,618,015)
1,471,746,396 
TEMPORARY CASH INVESTMENTS — 2.3%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $12,823,371), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $12,616,329) 12,616,266 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 0.125%, 7/15/30, valued at $22,426,837), at 0.06%, dated 10/30/20,
due 11/2/20 (Delivery value $21,987,110)
21,987,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 1,069  1,069 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $34,604,335)
34,604,335 
TEMPORARY CASH INVESTMENTS - SECURITIES LENDING COLLATERAL(3) — 1.2%
State Street Navigator Securities Lending Government Money Market Portfolio
(Cost $17,308,437)
17,308,437  17,308,437 
TOTAL INVESTMENT SECURITIES — 101.6%
(Cost $1,235,530,787)
1,523,659,168 
OTHER ASSETS AND LIABILITIES — (1.6)% (23,258,879)
TOTAL NET ASSETS — 100.0% $ 1,500,400,289 

FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
CAD 1,655,461  USD 1,239,906  Morgan Stanley 12/31/20 $ 3,085 
CAD 11,185,167  USD 8,403,986  Morgan Stanley 12/31/20 (5,680)
USD 46,529,581  CAD 62,021,606  Morgan Stanley 12/31/20 (38,917)
USD 1,232,714  CAD 1,649,623  Morgan Stanley 12/31/20 (5,894)
USD 1,106,081  CAD 1,469,741  Morgan Stanley 12/31/20 2,536 
USD 1,351,629  CAD 1,791,631  Morgan Stanley 12/31/20 6,395 
USD 4,261,860  CAD 5,684,742  Morgan Stanley 12/31/20 (6,490)
$ (44,965)

NOTES TO SCHEDULE OF INVESTMENTS
ADR - American Depositary Receipt
CAD - Canadian Dollar
USD - United States Dollar
(1)Non-income producing.
(2)Security, or a portion thereof, is on loan. At the period end, the aggregate value of securities on loan was $17,644,902. The amount of securities on loan indicated may not correspond with the securities on loan identified because securities with pending sales are in the process of recall from the brokers.
(3)Investment of cash collateral from securities on loan. At the period end, the aggregate value of the collateral held by the fund was $18,090,942, which includes securities collateral of $782,505.


See Notes to Financial Statements.
14



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $1,218,222,350) — including $17,644,902 of securities on loan $ 1,506,350,731 
Investment made with cash collateral received for securities on loan, at value
(cost of $17,308,437)
17,308,437 
Total investment securities, at value (cost of $1,235,530,787) 1,523,659,168 
Receivable for investments sold 18,297,082 
Receivable for capital shares sold 846,842 
Unrealized appreciation on forward foreign currency exchange contracts 12,016 
Dividends and interest receivable 6,167 
Securities lending receivable 82,993 
1,542,904,268 
Liabilities
Payable for collateral received for securities on loan 17,308,437 
Payable for investments purchased 22,925,331 
Payable for capital shares redeemed 1,064,455 
Unrealized depreciation on forward foreign currency exchange contracts 56,981 
Accrued management fees 1,118,787 
Distribution and service fees payable 29,988 
42,503,979 
Net Assets $ 1,500,400,289 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 1,054,906,642 
Distributable earnings 445,493,647 
$ 1,500,400,289 

Net Assets Shares Outstanding Net Asset Value Per Share
Investor Class, $0.01 Par Value $531,353,305 24,151,524 $22.00
I Class, $0.01 Par Value $317,466,348 13,976,088 $22.71
Y Class, $0.01 Par Value $130,957,763 5,689,423 $23.02
A Class, $0.01 Par Value $98,200,216 4,675,908 $21.00*
C Class, $0.01 Par Value $5,297,689 288,275 $18.38
R Class, $0.01 Par Value $8,492,235 418,377 $20.30
R5 Class, $0.01 Par Value $9,477 417 $22.73
R6 Class, $0.01 Par Value $108,820,003 4,729,299 $23.01
G Class, $0.01 Par Value $299,803,253 12,842,182 $23.35
*Maximum offering price $22.28 (net asset value divided by 0.9425).


See Notes to Financial Statements.

15



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $101,912) $ 4,510,929 
Securities lending, net 300,211 
Interest 135,020 
4,946,160 
Expenses:
Management fees 12,723,236 
Distribution and service fees:
A Class 215,627 
C Class 47,432 
R Class 36,175 
Directors' fees and expenses 37,893 
Other expenses 116 
13,060,479 
Fees waived - G Class (1,694,098)
11,366,381 
Net investment income (loss) (6,420,221)
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions 182,124,370 
Forward foreign currency exchange contract transactions 152,963 
Foreign currency translation transactions (1,411)
182,275,922 
Change in net unrealized appreciation (depreciation) on:
Investments 161,838,619 
Forward foreign currency exchange contracts 21,434 
Translation of assets and liabilities in foreign currencies (6,759)
161,853,294 
Net realized and unrealized gain (loss) 344,129,216 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 337,708,995 


See Notes to Financial Statements.

16



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ (6,420,221) $ (5,373,421)
Net realized gain (loss) 182,275,922  59,472,982 
Change in net unrealized appreciation (depreciation) 161,853,294  40,650,541 
Net increase (decrease) in net assets resulting from operations 337,708,995  94,750,102 
Distributions to Shareholders
From earnings:
Investor Class (25,227,608) (48,639,063)
I Class (16,816,143) (45,335,165)
Y Class (535,213) (276,649)
A Class (4,721,985) (10,279,016)
C Class (312,537) (867,837)
R Class (381,103) (773,910)
R5 Class (395) (905)
R6 Class (2,829,940) (4,560,472)
G Class (9,051,157) — 
Decrease in net assets from distributions (59,876,081) (110,733,017)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) 369,858,485  (19,942,776)
Net increase (decrease) in net assets 647,691,399  (35,925,691)
Net Assets
Beginning of period 852,708,890  888,634,581 
End of period $ 1,500,400,289  $ 852,708,890 


See Notes to Financial Statements.

17



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Small Cap Growth Fund (the fund) is one fund in a series issued by the corporation. The fund’s investment objective is to seek long-term capital growth.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge. Sale of the G Class commenced on April 1, 2019.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.
Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.
Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.
If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.


18



The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.
Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.
Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.
Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.
Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.
Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.
Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.


19



Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.
Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually. The fund may elect to treat a portion of its payment to a redeeming shareholder, which represents the pro rata share of undistributed net investment income and net realized gains, as a distribution for federal income tax purposes (tax equalization).
Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.
Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

The following table reflects a breakdown of transactions accounted for as secured borrowings, the gross obligation by the type of collateral pledged, and the remaining contractual maturity of those transactions as of October 31, 2020.

Remaining Contractual Maturity of Agreements
Overnight and
Continuous
<30 days
Between
30 & 90 days
>90 days
Total
Securities Lending Transactions(1)
Common Stocks $ 17,308,437  —  —  —  $ 17,308,437 
Gross amount of recognized liabilities for securities lending transactions $ 17,308,437 

(1)Amount represents the payable for cash collateral received for securities on loan. This will generally be in the Overnight and Continuous column as the securities are typically callable on demand.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. Various funds issued by American Century Asset Allocation Portfolios, Inc. own, in aggregate, 16% of the shares of the fund.


20



Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets). The investment advisor agreed to waive the G Class's management fee in its entirety. The investment advisor expects this waiver to remain in effect permanently and cannot terminate it without the approval of the Board of Directors.

The management fee schedule range and the effective annual management fee for each class for the period ended October 31, 2020 are as follows:
Management Fee
Schedule Range
Effective Annual
Management Fee
Investor Class 1.100% to 1.500% 1.21%
I Class 0.900% to 1.300% 1.01%
Y Class 0.750% to 1.150% 0.86%
A Class 1.100% to 1.500% 1.21%
C Class 1.100% to 1.500% 1.21%
R Class 1.100% to 1.500% 1.21%
R5 Class 0.900% to 1.300% 1.01%
R6 Class 0.750% to 1.150% 0.86%
G Class 0.750% to 1.150%
0.00%(1)
(1)Effective annual management fee before waiver was 0.86%.

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.
Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.
Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $12,972,887 and $1,628,000, respectively. The effect of interfund transactions on the Statement of Operations was $142,719 in net realized gain (loss) on investment transactions.

4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $1,807,926,013 and $1,648,435,828, respectively.

On August 13, 2020, the fund received investment securities valued at $133,320,673 from a purchase in kind from other products managed by the fund’s investment advisor. A purchase in kind occurs when a fund receives securities into its portfolio in lieu of cash as payment from a purchasing shareholder.
21



5. Capital Share Transactions
Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019(1)
Shares Amount Shares Amount
Investor Class/Shares Authorized 335,000,000  335,000,000 
Sold 9,921,702  $ 179,032,931  2,845,255  $ 48,155,202 
Issued in reinvestment of distributions 1,317,045  23,588,268  3,224,826  45,566,788 
Redeemed (9,495,829) (181,400,499) (5,030,701) (84,023,120)
1,742,918  21,220,700  1,039,380  9,698,870 
I Class/Shares Authorized 210,000,000  210,000,000 
Sold 14,257,641  281,464,270  2,861,828  48,997,525 
Issued in reinvestment of distributions 161,247  2,976,627  322,168  4,674,658 
Redeemed (17,359,714) (315,563,803) (6,320,416) (107,127,487)
(2,940,826) (31,122,906) (3,136,420) (53,455,304)
Y Class/Shares Authorized 30,000,000  30,000,000 
Sold 6,761,561  126,431,953  250,309  4,433,763 
Issued in reinvestment of distributions 28,652  535,213  18,884  276,649 
Redeemed (1,451,198) (30,110,005) (14,128) (249,802)
5,339,015  96,857,161  255,065  4,460,610 
A Class/Shares Authorized 70,000,000  70,000,000 
Sold 635,430  10,992,905  732,140  11,663,863 
Issued in reinvestment of distributions 267,760  4,586,734  722,004  9,804,810 
Redeemed (990,674) (17,325,103) (1,137,418) (18,386,791)
(87,484) (1,745,464) 316,726  3,081,882 
C Class/Shares Authorized 30,000,000  30,000,000 
Sold 75,490  1,255,719  48,287  670,563 
Issued in reinvestment of distributions 18,317  276,405  61,607  747,908 
Redeemed (126,131) (1,977,877) (180,322) (2,539,818)
(32,324) (445,753) (70,428) (1,121,347)
R Class/Shares Authorized 30,000,000  30,000,000 
Sold 215,915  3,705,057  151,546  2,348,495 
Issued in reinvestment of distributions 22,612  375,133  57,798  763,516 
Redeemed (193,648) (3,188,549) (168,574) (2,650,675)
44,879  891,641  40,770  461,336 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold —  —  1,498  25,253 
Issued in reinvestment of distributions 22  395  62  905 
Redeemed —  —  (1,553) (26,878)
22  395  (720)
R6 Class/Shares Authorized 50,000,000  50,000,000 
Sold 3,584,510  69,966,478  1,013,445  17,944,892 
Issued in reinvestment of distributions 151,577  2,829,940  311,295  4,560,472 
Redeemed (1,680,729) (33,221,028) (779,079) (13,919,920)
2,055,358  39,575,390  545,661  8,585,444 
G Class/Shares Authorized 140,000,000  140,000,000 
Sold 16,326,187  329,098,341  458,459  8,429,061 
Issued in reinvestment of distributions 481,445  9,051,157  —  — 
Redeemed (4,419,358) (93,522,177) (4,551) (82,608)
12,388,274  244,627,321  453,908  8,346,453 
Net increase (decrease) 18,509,832  $ 369,858,485  (555,331) $ (19,942,776)

(1)April 1, 2019 (commencement of sale) through October 31, 2019 for the G Class.
22



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.

The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 1,411,831,991  $ 59,914,405  — 
Temporary Cash Investments 1,069  34,603,266  — 
Temporary Cash Investments - Securities Lending Collateral 17,308,437  —  — 
$ 1,429,141,497  $ 94,517,671  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 12,016  — 
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 56,981  — 

7. Derivative Instruments

Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $38,771,910.

23



The value of foreign currency risk derivative instruments as of October 31, 2020, is disclosed on the Statement of Assets and Liabilities as an asset of $12,016 in unrealized appreciation on forward foreign currency exchange contracts and a liability of $56,981 in unrealized depreciation on forward foreign currency exchange contracts. For the year ended October 31, 2020, the effect of foreign currency risk derivative instruments on the Statement of Operations was $152,963 in net realized gain (loss) on forward foreign currency exchange contract transactions and $21,434 in change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts.

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

The fund invests in common stocks of small companies. Because of this, the fund may be subject to greater risk and market fluctuations than a fund investing in larger, more established companies.

The fund’s investment process may result in high portfolio turnover, which could mean high transaction costs, affecting both performance and capital gains tax liabilities to investors.

9. Federal Tax Information

On December 8, 2020, the fund declared and paid a per-share distribution from net realized gains to shareholders of record on December 7, 2020 of $2.7205 for the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:

2020 2019
Distributions Paid From
Ordinary income —  $ 21,323,960 
Long-term capital gains $ 59,876,081  $ 89,409,057 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 1,253,127,307 
Gross tax appreciation of investments $ 324,104,356 
Gross tax depreciation of investments (53,572,495)
Net tax appreciation (depreciation) of investments 270,531,861 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies (6,755)
Net tax appreciation (depreciation) $ 270,525,106 
Undistributed ordinary income $ 28,065,383 
Accumulated long-term gains $ 146,903,158 
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.
24



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net Realized Gains Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $17.54 (0.15) 5.61 5.46 (1.00) $22.00 32.43% 1.22% (0.81)% 141% $531,353
2019 $18.08 (0.12) 1.91 1.79 (2.33) $17.54 13.00% 1.28% (0.70)% 92% $392,956
2018 $16.70 (0.17) 1.65 1.48 (0.10) $18.08 8.89% 1.27% (0.93)% 116% $386,455
2017 $12.96 (0.13) 4.45 4.32 (0.58) $16.70 33.36% 1.36% (0.83)% 70% $361,029
2016 $13.06 (0.10)
(3)
(0.10) $12.96 (0.77)% 1.36% (0.83)% 130% $133,140
I Class
2020 $18.04 (0.11) 5.78 5.67 (1.00) $22.71 32.76% 1.02% (0.61)% 141% $317,466
2019 $18.50 (0.09) 1.96 1.87 (2.33) $18.04 13.16% 1.08% (0.50)% 92% $305,249
2018 $17.04 (0.14) 1.70 1.56 (0.10) $18.50 9.18% 1.07% (0.73)% 116% $371,030
2017 $13.20 (0.09) 4.51 4.42 (0.58) $17.04 33.51% 1.16% (0.63)% 70% $219,881
2016 $13.27 (0.08) 0.01 (0.07) $13.20 (0.53)% 1.16% (0.63)% 130% $269,094
Y Class
2020 $18.24 (0.10) 5.88 5.78 (1.00) $23.02 32.96% 0.87% (0.46)% 141% $130,958
2019 $18.65 (0.06) 1.98 1.92 (2.33) $18.24 13.34% 0.93% (0.35)% 92% $6,392
2018 $17.16 (0.07) 1.66 1.59 (0.10) $18.65 9.29% 0.92% (0.58)% 116% $1,778
2017(4)
$15.34 (0.06) 2.46 2.40 (0.58) $17.16 15.67%
1.01%(5)
(0.61)%(5)
70%(6)
$6




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net Realized Gains Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
A Class
2020 $16.82 (0.19) 5.37 5.18 (1.00) $21.00 32.14% 1.47% (1.06)% 141% $98,200
2019 $17.49 (0.16) 1.82 1.66 (2.33) $16.82 12.72% 1.53% (0.95)% 92% $80,127
2018 $16.19 (0.21) 1.61 1.40 (0.10) $17.49 8.61% 1.52% (1.18)% 116% $77,764
2017 $12.61 (0.16) 4.32 4.16 (0.58) $16.19 33.02% 1.61% (1.08)% 70% $80,654
2016 $12.74 (0.13)
(3)
(0.13) $12.61 (1.02)% 1.61% (1.08)% 130% $86,651
C Class
2020 $14.94 (0.28) 4.72 4.44 (1.00) $18.38 31.18% 2.22% (1.81)% 141% $5,298
2019 $15.92 (0.25) 1.60 1.35 (2.33) $14.94 11.84% 2.28% (1.70)% 92% $4,790
2018 $14.86 (0.32) 1.48 1.16 (0.10) $15.92 7.83% 2.27% (1.93)% 116% $6,227
2017 $11.70 (0.25) 3.99 3.74 (0.58) $14.86 31.99% 2.36% (1.83)% 70% $9,958
2016 $11.91 (0.21)
(3)
(0.21) $11.70 (1.68)% 2.36% (1.83)% 130% $9,146
R Class
2020 $16.33 (0.23) 5.20 4.97 (1.00) $20.30 31.80% 1.72% (1.31)% 141% $8,492
2019 $17.09 (0.19) 1.76 1.57 (2.33) $16.33 12.39% 1.78% (1.20)% 92% $6,099
2018 $15.86 (0.25) 1.58 1.33 (0.10) $17.09 8.41% 1.77% (1.43)% 116% $5,687
2017 $12.40 (0.19) 4.23 4.04 (0.58) $15.86 32.61% 1.86% (1.33)% 70% $3,761
2016 $12.55 (0.16) 0.01 (0.15) $12.40 (1.20)% 1.86% (1.33)% 130% $2,672




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
Distributions From Net Realized Gains Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R5 Class
2020 $18.05 (0.12) 5.80 5.68 (1.00) $22.73 32.74% 1.02% (0.61)% 141% $9
2019 $18.51 (0.08) 1.95 1.87 (2.33) $18.05 13.21% 1.08% (0.50)% 92% $7
2018 $17.05 (0.14) 1.70 1.56 (0.10) $18.51 9.12% 1.07% (0.73)% 116% $7
2017(4)
$15.26 (0.07) 2.44 2.37 (0.58) $17.05 15.56%
1.16%(5)
(0.76)%(5)
70%(6)
$6
R6 Class
2020 $18.24 (0.09) 5.86 5.77 (1.00) $23.01 32.91% 0.87% (0.46)% 141% $108,820
2019 $18.65 (0.06) 1.98 1.92 (2.33) $18.24 13.40% 0.93% (0.35)% 92% $48,763
2018 $17.15 (0.11) 1.71 1.60 (0.10) $18.65 9.30% 0.92% (0.58)% 116% $39,687
2017 $13.26 (0.08) 4.55 4.47 (0.58) $17.15 33.74% 1.01% (0.48)% 70% $28,077
2016 $13.31 (0.06) 0.01 (0.05) $13.26 (0.38)% 1.01% (0.48)% 130% $25,992
G Class
2020 $18.34 0.08 5.93 6.01 (1.00) $23.35 34.09%
0.01%(7)
0.40%(7)
141% $299,803
2019(8)
$17.43 0.05 0.86 0.91 $18.34 5.22%
0.00%(5)(9)(10)
0.52%(5)(10)
92%(11)
$8,326




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)Per-share amount was less than $0.005.
(4)April 10, 2017 (commencement of sale) through October 31, 2017.
(5)Annualized.
(6)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.
(7)The ratio of operating expenses to average net assets before expense waiver and the ratio of net investment income (loss) to average net assets before expense waiver was 0.87% and (0.46)%, respectively.
(8)April 1, 2019 (commencement of sale) through October 31, 2019.
(9)Ratio was less than 0.005%.
(10)The annualized ratio of operating expenses to average net assets before expense waiver and the annualized ratio of net investment income (loss) to average net assets before expense waiver was 0.93% and (0.41)%, respectively.
(11)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2019.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Small Cap Growth Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Small Cap Growth Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.
29



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
30



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
31



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





32



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
33



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-, three-, five-, and ten-year periods reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
34



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was above the median of the total expense ratios of the Fund’s peer expense universe
35



and was within the range of its peer expense group. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
36



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



37



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates $66,099,273, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.

The fund hereby designates $1,173,649 as qualified short-term capital gain distributions for purposes of Internal Revenue Code Section 871 for the fiscal year ended October 31, 2020.

The fund utilized earnings and profits of $7,396,841 distributed to shareholders on redemption of shares as part of the dividends paid deduction (tax equalization).
38



Notes
39



Notes

40








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
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Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90978 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Sustainable Equity Fund
Investor Class (AFDIX)
I Class (AFEIX)
Y Class (AFYDX)
A Class (AFDAX)
C Class (AFDCX)
R Class (AFDRX)
R5 Class (AFDGX)
R6 Class (AFEDX)
G Class (AFEGX)














Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.











Table of Contents
President's Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
15
Statement of Operations
16
Statement of Changes in Net Assets
17
Notes to Financial Statements
18
Financial Highlights
26
Report of Independent Registered Public Accounting Firm
30
Management
31
Approval of Management Agreement
34
Additional Information
38






















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
Total Returns as of October 31, 2020
    Average Annual Returns
  Ticker
Symbol
1 year 5 years 10 years Since Inception Inception
Date
Investor Class AFDIX 11.33% 11.98% 13.03% 7/29/05
S&P 500 Index 9.71% 11.70% 13.00%
I Class AFEIX 11.55% 12.21% 13.27% 7/29/05
Y Class AFYDX 11.70% 13.96% 4/10/17
A Class AFDAX 11/30/04
No sales charge 11.07% 11.71% 12.76%
With sales charge 4.68% 10.40% 12.09%
C Class AFDCX 10.22% 10.87% 11.92% 11/30/04
R Class AFDRX 10.77% 11.42% 12.47% 7/29/05
R5 Class AFDGX 11.55% 13.79% 4/10/17
R6 Class AFEDX 11.70% 13.18% 4/1/19
G Class AFEGX 12.21% 13.69% 4/1/19
Average annual returns since inception are presented when ten years of performance history is not available.
Fund returns would have been lower if a portion of the fees had not been waived.

Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.



















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-210FB57F00E94DF88C81.JPG
Value on October 31, 2020
Investor Class — $34,084
S&P 500 Index — $33,987
Ending value of Investor Class would have been lower if a portion of the fees had not been waived.
Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class G Class
0.80% 0.60% 0.45% 1.05% 1.80% 1.30% 0.60% 0.45% 0.45%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.











Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary

Portfolio Managers: Greg Woodhams, Justin Brown, Joe Reiland and Rob Bove

Performance Summary

Sustainable Equity returned 11.33%* for the 12 months ended October 31, 2020, outpacing the 9.71% return of the fund’s benchmark, the S&P 500 Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the S&P 500 Index, information technology and consumer discretionary stocks posted the largest gains. The energy sector fell sharply amid weakening demand and a notable decline in oil prices.

Stock selection in the real estate and information technology sectors helped drive outperformance relative to the benchmark. An overweight allocation to information technology was also helpful. Stock decisions in the health care and energy sectors detracted.

Real Estate and Information Technology Led Performance

Stock selection in the real estate sector was a top contributor. A leading source of strength was Prologis, an equity real estate investment trust (REIT) that owns primarily logistics and distribution center properties, which benefited from the surge in e-commerce. REITs were also supported by low interest rates as the Federal Reserve provided stimulus to the pandemic-stricken economy.

In the information technology sector, stock choices in the IT services industry led relative performance. The stock price of PayPal Holdings, the leader in online payments, benefited from the increasing demand for digital transactions, a secular trend that has been aided by stay-at-home restrictions during the pandemic. In the software industry, Microsoft was a top contributor, buoyed by the breadth of its businesses, its transition to a subscription model and strength in its cloud division. NVIDIA reported positive results and raised guidance due to strong demand for its chips used in data centers and gaming. The data center business is being driven by the launch of new products that are based on a new architecture and a leading process node, which is driving better price and performance per chip.

Elsewhere, not owning two oil companies that are components of the benchmark helped relative performance. Exxon Mobil faltered along with the sector as reduced energy demand and low prices weighed on revenues. Investors worried about the sustainability of its dividend, and the stock was removed from the Dow Jones Industrial Average at the end of August. Not owning Chevron helped relative performance due to lower-than-expected earnings amid falling oil prices. This was another victim of economic weakness resulting from a surge in COVID-19 cases and uncertainty about the pace of the recovery.

Health Care Stocks Detracted

Overall stock selection in the health care sector detracted, mostly driven by choices in the health care equipment and supplies industry. The pandemic hurt several health care segments. Medical device makers in particular were hampered by fewer elective procedures because of the pandemic.


*All fund returns referenced in this commentary are for Investor Class shares. Fund returns would have been lower had a portion of the fees not been waived. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.

5



The energy sector especially felt the impact of the pandemic. Plunging oil prices and weak demand as the global economy shut down caused most energy stocks to fall, including ONEOK, a diversified energy company with a large stake in pipelines. We eliminated ONEOK as the energy sector is likely to see considerable weakness due to uncertainty around the timing and magnitude of an eventual economic recovery. ConocoPhillips also detracted. The oil giant’s stock fell after the company reported disappointing results due to declining oil prices and low production. Phillips 66 was another casualty. The economic slowdown caused by the pandemic resulted in reduced demand for refined oil, which hurt that segment of Phillips 66’s business. Profit margins and earnings fell along with demand for gasoline, jet fuel and related products.

Among other notable individual detractors from relative returns, Bank of America underperformed as interest rates fell to zero. In addition, slower economic growth and high unemployment were expected to lead to credit losses and slow new-loan generation. The travel industry was also hit hard by the pandemic. Royal Caribbean Cruises was a significant detractor. Sailings were canceled, and those revenues likely won’t come back anytime soon, even after the worst of the virus has passed. Fares will also likely have to be lower across the industry to drive bookings in the foreseeable future. We eliminated our holding.

Outlook

The portfolio invests in a blend of large value and large growth stocks, while seeking to outperform the S&P 500 Index with a comparable dividend yield without taking on significant additional risk. We believe that companies exhibiting both improving business fundamentals and sustainable corporate behaviors will outperform over time. We use a quantitative model that combines fundamental measures of a stock’s value and growth potential. We then integrate our view of the company’s financial improvement with multiple sources of environmental, social and governance data.

As of October 31, 2020, the portfolio’s largest overweight position relative to the benchmark was in the industrials sector. Communication services ended the period as the largest underweight sector.

























A strategy or emphasis on environmental, social and governance factors (ESG) may limit the investment opportunities available to a portfolio. Therefore, the portfolio may underperform or perform differently than other portfolios that do not have an ESG investment focus. A portfolio's ESG investment focus may also result in the portfolio investing in securities or industry sectors that perform differently or maintain a different risk profile than the market generally or compared to underlying holdings that are not screened for ESG standards.
6



Fund Characteristics
October 31, 2020
Top Ten Holdings % of net assets
Microsoft Corp. 7.0%
Apple, Inc. 6.2%
Amazon.com, Inc. 4.8%
Alphabet, Inc., Class A 3.7%
Procter & Gamble Co. (The) 2.2%
Prologis, Inc. 2.2%
NextEra Energy, Inc. 2.2%
Facebook, Inc., Class A 2.1%
Home Depot, Inc. (The) 2.0%
NVIDIA Corp. 1.8%
Top Five Industries % of net assets
Software 8.9%
Technology Hardware, Storage and Peripherals 6.2%
Interactive Media and Services 5.8%
Internet and Direct Marketing Retail 5.4%
IT Services 5.3%
Types of Investments in Portfolio % of net assets
Common Stocks 96.9%
Temporary Cash Investments 2.8%
Other Assets and Liabilities 0.3%

7



Shareholder Fee Example

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.
8




Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
Investor Class $1,000 $1,141.90 $4.25 0.79%
I Class $1,000 $1,143.30 $3.18 0.59%
Y Class $1,000 $1,143.80 $2.37 0.44%
A Class $1,000 $1,140.60 $5.60 1.04%
C Class $1,000 $1,136.20 $9.61 1.79%
R Class $1,000 $1,139.20 $6.94 1.29%
R5 Class $1,000 $1,143.20 $3.18 0.59%
R6 Class $1,000 $1,144.00 $2.37 0.44%
G Class $1,000 $1,146.90 $0.00
0.00%(2)
Hypothetical
Investor Class $1,000 $1,021.17 $4.01 0.79%
I Class $1,000 $1,022.17 $3.00 0.59%
Y Class $1,000 $1,022.93 $2.24 0.44%
A Class $1,000 $1,019.91 $5.28 1.04%
C Class $1,000 $1,016.14 $9.07 1.79%
R Class $1,000 $1,018.65 $6.55 1.29%
R5 Class $1,000 $1,022.17 $3.00 0.59%
R6 Class $1,000 $1,022.93 $2.24 0.44%
G Class $1,000 $1,025.14 $0.00
0.00%(2)
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
(2)Other expenses, which include directors' fees and expenses, did not exceed 0.005%.
9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 96.9%
Aerospace and Defense — 0.9%
Lockheed Martin Corp. 70,746  $ 24,770,297 
Air Freight and Logistics — 0.4%
Expeditors International of Washington, Inc. 129,022  11,401,674 
Auto Components — 0.9%
Aptiv plc 247,418  23,873,363 
Banks — 3.4%
Bank of America Corp. 1,657,238  39,276,541 
JPMorgan Chase & Co. 375,234  36,787,941 
Regions Financial Corp. 1,276,032  16,971,226 
93,035,708 
Beverages — 1.5%
PepsiCo, Inc. 300,068  39,996,064 
Biotechnology — 2.3%
AbbVie, Inc. 282,759  24,062,791 
Amgen, Inc. 138,678  30,084,805 
Vertex Pharmaceuticals, Inc.(1)
47,771  9,953,566 
64,101,162 
Building Products — 1.8%
Johnson Controls International plc 610,256  25,758,906 
Masco Corp. 415,366  22,263,617 
48,022,523 
Capital Markets — 4.0%
Ameriprise Financial, Inc. 74,804  12,030,728 
BlackRock, Inc. 37,449  22,439,815 
Intercontinental Exchange, Inc. 166,185  15,687,864 
Morgan Stanley 601,753  28,974,407 
S&P Global, Inc. 97,170  31,359,674 
110,492,488 
Chemicals — 2.8%
Air Products and Chemicals, Inc. 48,647  13,438,247 
Ecolab, Inc. 74,424  13,663,502 
Linde plc 130,378  28,727,489 
Sherwin-Williams Co. (The) 28,141  19,360,445 
75,189,683 
Communications Equipment — 0.6%
Cisco Systems, Inc. 491,800  17,655,620 
Consumer Finance — 0.5%
American Express Co. 161,071  14,696,118 
Containers and Packaging — 0.8%
Ball Corp. 234,935  20,909,215 
Diversified Telecommunication Services — 1.2%
Verizon Communications, Inc. 583,057  33,228,418 
Electric Utilities — 2.2%
NextEra Energy, Inc. 821,648  60,152,850 
Electrical Equipment — 0.5%
Eaton Corp. plc 138,330  14,357,271 
10



Shares Value
Electronic Equipment, Instruments and Components — 1.5%
CDW Corp. 56,823  $ 6,966,500 
Cognex Corp. 181,929  11,989,121 
Keysight Technologies, Inc.(1)
197,220  20,682,461 
39,638,082 
Entertainment — 1.5%
Activision Blizzard, Inc. 198,629  15,042,174 
Walt Disney Co. (The) 222,632  26,994,130 
42,036,304 
Equity Real Estate Investment Trusts (REITs) — 3.0%
Prologis, Inc. 609,826  60,494,739 
SBA Communications Corp. 70,766  20,548,324 
81,043,063 
Food and Staples Retailing — 1.3%
Costco Wholesale Corp. 47,372  16,941,174 
Sysco Corp. 311,315  17,218,833 
34,160,007 
Food Products — 0.9%
Beyond Meat, Inc.(1)
7,080  1,008,404 
Mondelez International, Inc., Class A 380,309  20,202,014 
Vital Farms, Inc.(1)
101,130  3,495,053 
24,705,471 
Health Care Equipment and Supplies — 2.0%
Baxter International, Inc. 71,661  5,558,744 
Edwards Lifesciences Corp.(1)
268,729  19,265,182 
Medtronic plc 222,924  22,419,467 
ResMed, Inc. 31,823  6,108,106 
53,351,499 
Health Care Providers and Services — 3.0%
Cigna Corp. 73,597  12,288,491 
CVS Health Corp. 348,341  19,538,447 
Humana, Inc. 36,726  14,663,957 
UnitedHealth Group, Inc. 119,612  36,498,406 
82,989,301 
Hotels, Restaurants and Leisure — 0.5%
Chipotle Mexican Grill, Inc.(1)
12,268  14,739,757 
Household Products — 2.8%
Colgate-Palmolive Co. 201,909  15,928,601 
Procter & Gamble Co. (The) 445,587  61,089,978 
77,018,579 
Industrial Conglomerates — 1.2%
Honeywell International, Inc. 195,219  32,201,374 
Insurance — 1.3%
Aflac, Inc. 154,333  5,239,605 
Marsh & McLennan Cos., Inc. 105,345  10,898,994 
Progressive Corp. (The) 91,322  8,392,492 
Prudential Financial, Inc. 86,240  5,521,085 
Travelers Cos., Inc. (The) 53,522  6,460,640 
36,512,816 
Interactive Media and Services — 5.8%
Alphabet, Inc., Class A(1)
62,638  101,229,898 
Facebook, Inc., Class A(1)
220,558  58,031,016 
159,260,914 
11



Shares Value
Internet and Direct Marketing Retail — 5.4%
Amazon.com, Inc.(1)
43,589  $ 132,342,742 
Expedia Group, Inc. 170,447  16,047,585 
148,390,327 
IT Services — 5.3%
Accenture plc, Class A 135,273  29,342,067 
Mastercard, Inc., Class A 119,003  34,349,026 
PayPal Holdings, Inc.(1)
229,324  42,684,076 
Visa, Inc., Class A 204,603  37,178,411 
143,553,580 
Life Sciences Tools and Services — 2.2%
Agilent Technologies, Inc. 219,872  22,446,733 
Thermo Fisher Scientific, Inc. 82,034  38,811,926 
61,258,659 
Machinery — 1.8%
Cummins, Inc. 114,756  25,233,697 
Parker-Hannifin Corp. 114,642  23,886,807 
49,120,504 
Media — 0.7%
Comcast Corp., Class A 464,464  19,618,959 
Multiline Retail — 0.4%
Target Corp. 79,345  12,077,896 
Oil, Gas and Consumable Fuels — 0.9%
ConocoPhillips 576,848  16,509,390 
Phillips 66 162,555  7,584,816 
24,094,206 
Personal Products — 0.4%
Estee Lauder Cos., Inc. (The), Class A 53,898  11,839,235 
Pharmaceuticals — 3.5%
Bristol-Myers Squibb Co. 492,596  28,792,236 
Merck & Co., Inc. 450,541  33,885,189 
Novo Nordisk A/S, B Shares 244,487  15,635,376 
Zoetis, Inc. 107,738  17,081,860 
95,394,661 
Professional Services — 0.9%
IHS Markit Ltd. 292,635  23,665,392 
Road and Rail — 1.8%
Norfolk Southern Corp. 95,016  19,869,746 
Union Pacific Corp. 161,113  28,547,612 
48,417,358 
Semiconductors and Semiconductor Equipment — 5.0%
Advanced Micro Devices, Inc.(1)
197,091  14,838,981 
Applied Materials, Inc. 187,182  11,086,790 
ASML Holding NV 54,044  19,647,950 
Broadcom, Inc. 53,302  18,635,978 
NVIDIA Corp. 98,449  49,358,391 
Texas Instruments, Inc. 156,934  22,691,087 
136,259,177 
Software — 8.9%
Adobe, Inc.(1)
56,655  25,330,451 
Microsoft Corp. 949,103  192,164,884 
salesforce.com, Inc.(1)
107,093  24,874,491 
242,369,826 
12



Shares Value
Specialty Retail — 3.0%
Home Depot, Inc. (The) 208,967  $ 55,733,588 
TJX Cos., Inc. (The) 501,961  25,499,619 
81,233,207 
Technology Hardware, Storage and Peripherals — 6.2%
Apple, Inc. 1,553,214  169,082,876 
Textiles, Apparel and Luxury Goods — 1.9%
NIKE, Inc., Class B 317,928  38,176,794 
VF Corp. 189,700  12,747,840 
50,924,634 
TOTAL COMMON STOCKS
(Cost $2,273,426,429)
2,646,840,118 
TEMPORARY CASH INVESTMENTS — 2.8%
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%, 6/30/21 - 11/15/48, valued at $28,245,093), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $27,789,056) 27,788,917 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 0.125%, 7/15/30, valued at $49,397,645), at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $48,429,242) 48,429,000 
State Street Institutional U.S. Government Money Market Fund, Premier Class 2,312  2,312 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $76,220,229)
76,220,229 
TOTAL INVESTMENT SECURITIES — 99.7%
(Cost $2,349,646,658)
2,723,060,347 
OTHER ASSETS AND LIABILITIES — 0.3% 9,463,965 
TOTAL NET ASSETS — 100.0% $ 2,732,524,312 

FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
EUR 695,952  USD 816,902  Credit Suisse AG 12/31/20 $ (5,180)
EUR 413,437  USD 490,981  Credit Suisse AG 12/31/20 (8,771)
EUR 496,124  USD 587,665  Credit Suisse AG 12/31/20 (9,012)
USD 16,632,031  EUR 14,169,391  Credit Suisse AG 12/31/20 105,598 
USD 528,399  EUR 450,187  Credit Suisse AG 12/31/20 3,325 
USD 535,110  EUR 452,483  Credit Suisse AG 12/31/20 7,357 
USD 873,144  EUR 741,889  Credit Suisse AG 12/31/20 7,844 
$ 101,161 

FUTURES CONTRACTS PURCHASED
Reference Entity Contracts Expiration Date Notional
Amount
Unrealized
Appreciation
(Depreciation)^
S&P 500 E-Mini 449 December 2020 $ 73,292,515  $ (2,283,894)

^Amount represents value and unrealized appreciation (depreciation).

13



NOTES TO SCHEDULE OF INVESTMENTS
EUR - Euro
USD - United States Dollar
(1)Non-income producing.


See Notes to Financial Statements.
14



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $2,349,646,658) $ 2,723,060,347 
Deposits with broker for futures contracts 5,388,000 
Receivable for capital shares sold 3,387,271 
Unrealized appreciation on forward foreign currency exchange contracts 124,124 
Dividends and interest receivable 2,982,544 
2,734,942,286 
Liabilities
Payable for capital shares redeemed 713,148 
Payable for variation margin on futures contracts 1,059,040 
Unrealized depreciation on forward foreign currency exchange contracts 22,963 
Accrued management fees 597,943 
Distribution and service fees payable 24,880 
2,417,974 
Net Assets $ 2,732,524,312 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 2,451,869,922 
Distributable earnings 280,654,390 
$ 2,732,524,312 

Net Assets Shares Outstanding Net Asset Value Per Share
Investor Class, $0.01 Par Value $595,556,710 17,707,423 $33.63
I Class, $0.01 Par Value $245,758,736 7,281,829 $33.75
Y Class, $0.01 Par Value $8,115,118 240,004 $33.81
A Class, $0.01 Par Value $54,637,872 1,634,446 $33.43*
C Class, $0.01 Par Value $10,178,219 314,456 $32.37
R Class, $0.01 Par Value $9,014,143 271,939 $33.15
R5 Class, $0.01 Par Value $3,194,889 94,610 $33.77
R6 Class, $0.01 Par Value $5,149,675 152,157 $33.84
G Class, $0.01 Par Value $1,800,918,950 53,021,103 $33.97
*Maximum offering price $35.47 (net asset value divided by 0.9425).


See Notes to Financial Statements.

15



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $62,619) $ 34,347,338 
Interest 187,541 
Securities lending, net 5,449 
34,540,328 
Expenses:
Management fees 12,113,725 
Distribution and service fees:
A Class 136,241 
C Class 97,519 
R Class 32,240 
Directors' fees and expenses 65,600 
Other expenses 20,415 
12,465,740 
Fees waived(1)
(6,245,688)
6,220,052 
Net investment income (loss) 28,320,276 
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions (104,596,255)
Forward foreign currency exchange contract transactions (614,166)
Futures contract transactions (7,766,381)
Foreign currency translation transactions (4,810)
(112,981,612)
Change in net unrealized appreciation (depreciation) on:
Investments 283,791,380 
Forward foreign currency exchange contracts 128,688 
Futures contracts (2,283,894)
Translation of assets and liabilities in foreign currencies (365)
281,635,809 
Net realized and unrealized gain (loss) 168,654,197 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 196,974,473 

(1)Amount consists of $185,152, $52,538, $20,216, $19,997, $3,608, $2,165, $541, $1,301 and $5,960,170 for Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class, respectively.


See Notes to Financial Statements.

16



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets
October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ 28,320,276  $ 3,393,891 
Net realized gain (loss) (112,981,612) 14,582,318 
Change in net unrealized appreciation (depreciation) 281,635,809  26,832,590 
Net increase (decrease) in net assets resulting from operations 196,974,473  44,808,799 
Distributions to Shareholders
From earnings:
Investor Class (3,259,073) (9,479,446)
I Class (962,442) (2,679,164)
Y Class (510,247) (1,208,845)
A Class (364,241) (3,252,169)
C Class (67,854) (629,682)
R Class (31,560) (210,019)
R5 Class (11,626) (93,131)
R6 Class (18,679) — 
G Class (14,189,132) — 
Decrease in net assets from distributions (19,414,854) (17,552,456)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) 1,707,601,522  558,177,061 
Net increase (decrease) in net assets 1,885,161,141  585,433,404 
Net Assets
Beginning of period 847,363,171  261,929,767 
End of period $ 2,732,524,312  $ 847,363,171 


See Notes to Financial Statements.

17



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Sustainable Equity Fund (the fund) is one fund in a series issued by the corporation. The fund’s investment objective is to seek long-term capital growth. Income is a secondary objective. The fund is not permitted to invest in securities issued by companies assigned the Global Industry Classification Standard or the Bloomberg Industry Classification Standard for the tobacco industry.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge. Sale of the R6 Class and G Class commenced on April 1, 2019.
2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.

Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.

Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Exchange-traded futures contracts are valued at the settlement price as provided by the appropriate exchange. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.

If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.


18



The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.

Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.

Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.
Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.

Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.

Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.

Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.


19



Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.

Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually.

Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.

Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC. Various funds issued by American Century Asset Allocation Portfolios, Inc. own, in aggregate, 52% of the shares of the fund. Related parties do not invest in the fund for the purpose of exercising management or control.
Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets). From November 1, 2019 through July 31, 2020, the investment advisor agreed to waive 0.05% of the fund’s management fee. Effective August 1, 2020, the investment advisor terminated the waiver and decreased the annual management fee by 0.05%. The investment advisor agreed to waive the G Class’s management fee in its entirety. The investment advisor expects this waiver to remain in effect permanently and cannot terminate it without the approval of the Board of Directors.

20



The management fee schedule range and the effective annual management fee before and after waiver for each class for the period ended October 31, 2020 are as follows:
Effective Annual Management Fee
Management Fee
Schedule Range*
Before Waiver
After Waiver
Investor Class 0.750% to 0.790% 0.83% 0.79%
I Class 0.550% to 0.590% 0.63% 0.59%
Y Class 0.400% to 0.440% 0.48% 0.44%
A Class 0.750% to 0.790% 0.83% 0.79%
C Class 0.750% to 0.790% 0.83% 0.79%
R Class 0.750% to 0.790% 0.83% 0.79%
R5 Class 0.550% to 0.590% 0.63% 0.59%
R6 Class 0.400% to 0.440% 0.48% 0.44%
G Class 0.400% to 0.440% 0.48% 0.00%
*Prior to August 1, 2020, the management fee schedule range was 0.800% to 0.840% for Investor Class, A Class, C Class and R Class, 0.600% to 0.640% for I Class and R5 Class, 0.450% to 0.490% for Y Class, R6 Class and G Class.

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.

Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.

Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases were $9,165,216 and there were no interfund sales.
4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $1,575,488,143 and $725,148,983, respectively.

On July 22, 2020, the fund received investment securities valued at $774,285,429 from a purchase in kind from other products managed by the fund’s investment advisor. A purchase in kind occurs when a fund receives securities into its portfolio in lieu of cash as payment from a purchasing shareholder.

21



5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019(1)
Shares Amount Shares Amount
Investor Class/Shares Authorized 230,000,000  230,000,000 
Sold 17,239,793  $ 543,096,618  1,478,661  $ 42,448,717 
Issued in reinvestment of distributions 100,919  3,228,400  373,564  9,230,761 
Redeemed (3,521,917) (109,408,579) (3,033,709) (85,434,146)
13,818,795  436,916,439  (1,181,484) (33,754,668)
I Class/Shares Authorized 50,000,000  50,000,000 
Sold 5,143,550  162,491,745  2,840,717  80,856,818 
Issued in reinvestment of distributions 26,744  857,150  88,125  2,181,089 
Redeemed (1,372,675) (42,143,506) (795,266) (22,113,079)
3,797,619  121,205,389  2,133,576  60,924,828 
Y Class/Shares Authorized 30,000,000  30,000,000 
Sold 817,327  25,138,027  1,298,628  36,812,959 
Issued in reinvestment of distributions 15,895  509,737  48,822  1,208,845 
Redeemed (2,263,503) (74,266,512) (188,570) (5,485,398)
(1,430,281) (48,618,748) 1,158,880  32,536,406 
A Class/Shares Authorized 50,000,000  50,000,000 
Sold 333,847  10,430,358  279,004  7,723,840 
Issued in reinvestment of distributions 10,059  320,586  113,811  2,808,849 
Redeemed (501,546) (15,535,923) (398,221) (11,099,073)
(157,640) (4,784,979) (5,406) (566,384)
C Class/Shares Authorized 30,000,000  30,000,000 
Sold 89,054  2,800,693  71,758  1,908,443 
Issued in reinvestment of distributions 1,854  57,571  22,210  538,156 
Redeemed (119,796) (3,670,138) (160,965) (4,368,416)
(28,888) (811,874) (66,997) (1,921,817)
R Class/Shares Authorized 30,000,000  30,000,000 
Sold 215,132  6,842,044  65,244  1,825,976 
Issued in reinvestment of distributions 997  31,560  8,544  210,019 
Redeemed (92,477) (2,693,315) (40,894) (1,140,492)
123,652  4,180,289  32,894  895,503 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold 58,252  1,990,201  3,133  89,963 
Issued in reinvestment of distributions 350  11,238  3,761  93,131 
Redeemed (7,052) (207,323) (11,350) (311,587)
51,550  1,794,116  (4,456) (128,493)
R6 Class/Shares Authorized 50,000,000  50,000,000 
Sold 250,249  7,873,896  154,326  4,599,937 
Issued in reinvestment of distributions 582  18,679  —  — 
Redeemed (228,865) (7,676,224) (24,135) (733,659)
21,966  216,351  130,191  3,866,278 
G Class/Shares Authorized 525,000,000  525,000,000 
Sold 48,405,679  1,575,927,164  16,265,238  496,972,039 
Issued in reinvestment of distributions 442,167  14,189,132  —  — 
Redeemed (12,070,100) (392,611,757) (21,881) (646,631)
36,777,746  1,197,504,539  16,243,357  496,325,408 
Net increase (decrease) 52,974,519  $ 1,707,601,522  18,440,555  $ 558,177,061 
(1)April 1, 2019 (commencement of sale) through October 31, 2019 for the R6 Class and G Class.
22



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 2,611,556,792  $ 35,283,326 
Temporary Cash Investments 2,312 76,217,917
$ 2,611,559,104  $ 111,501,243 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts $ 124,124 
Liabilities
Other Financial Instruments
Futures Contracts $ 2,283,894 
Forward Foreign Currency Exchange Contracts $ 22,963 
$ 2,283,894  $ 22,963 

7. Derivative Instruments

Equity Price Risk — The fund is subject to equity price risk in the normal course of pursuing its investment objectives. A fund may enter into futures contracts based on an equity index in order to manage its exposure to changes in market conditions. A fund may purchase futures contracts to gain exposure to increases in market value or sell futures contracts to protect against a decline in market value. Upon entering into a futures contract, a fund is required to deposit either cash or securities in an amount equal to a certain percentage of the contract value (initial margin). Subsequent payments (variation margin) are made or received daily, in cash, by a fund. The variation margin is equal to the daily change in the contract value and is recorded as unrealized gains and losses. A fund recognizes a realized gain or loss when the contract is closed or expires. Net realized and unrealized gains or losses occurring during the holding period of futures contracts are a component of net realized gain (loss) on futures contract transactions and change in net unrealized appreciation (depreciation) on futures contracts, respectively. One of the risks of entering into futures contracts is the possibility that the change in value of the contract may not correlate with the changes in value of the underlying securities. The fund's average notional exposure to equity price risk derivative instruments held during the period was $22,559,689 futures contracts purchased.
23



Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $18,095,531.

Value of Derivative Instruments as of October 31, 2020
Asset Derivatives
Liability Derivatives
Type of Risk Exposure Location on Statement of Assets and Liabilities
Value
Location on Statement of Assets and Liabilities
Value
Equity Price Risk Receivable for variation margin on futures contracts* —  Payable for variation margin on futures contracts* $ 1,059,040 
Foreign Currency Risk Unrealized appreciation on forward foreign currency exchange contracts $ 124,124  Unrealized depreciation on forward foreign currency exchange contracts 22,963 
$ 124,124  $ 1,082,003 

* Included in the unrealized appreciation (depreciation) on futures contracts, as reported in the Schedule of Investments.

Effect of Derivative Instruments on the Statement of Operations for the Year Ended October 31, 2020
Net Realized Gain (Loss)
Change in Net Unrealized
Appreciation (Depreciation)
Type of Risk Exposure Location on Statement of Operations
Value
Location on Statement of Operations
Value
Equity Price Risk Net realized gain (loss) on futures contract transactions $ (7,766,381) Change in net unrealized appreciation (depreciation) on futures contracts $ (2,283,894)
Foreign Currency Risk Net realized gain (loss) on forward foreign currency exchange contract transactions (614,166) Change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts 128,688 
$ (8,380,547) $ (2,155,206)

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

24



9. Federal Tax Information

On December 8, 2020, the fund declared and paid the following per-share distributions from net investment
income to shareholders of record on December 7, 2020:
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class G Class
$0.1559 $0.2314 $0.2881 $0.0614 $0.2314 $0.2881 $0.4543

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income $ 7,163,302  $ 2,630,877 
Long-term capital gains $ 12,251,552  $ 14,921,579 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.
As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 2,375,197,191 
Gross tax appreciation of investments $ 402,484,485 
Gross tax depreciation of investments (54,621,329)
Net tax appreciation (depreciation) of investments 347,863,156 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 1,300 
Net tax appreciation (depreciation) $ 347,864,456 
Undistributed ordinary income $ 22,952,967 
Accumulated short-term capital losses $ (86,617,491)
Accumulated long-term capital losses $ (3,545,542)
The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.

Accumulated capital losses represent net capital loss carryovers that may be used to offset future realized capital gains for federal income tax purposes. The capital loss carryovers may be carried forward for an unlimited period. Future capital loss carryover utilization in any given year may be subject to Internal Revenue Code limitations.

25



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $30.40 0.28 3.15 3.43 (0.20) (0.20) $33.63 11.33% 0.79% 0.83% 0.88% 0.84% 36% $595,557
2019 $28.19 0.33 3.77 4.10 (0.22) (1.67) (1.89) $30.40 16.10% 0.80% 0.84% 1.14% 1.10% 33% $118,225
2018 $27.22 0.26 1.52 1.78 (0.20) (0.61) (0.81) $28.19 6.60% 0.95% 0.95% 0.91% 0.91% 41% $142,923
2017 $21.75 0.23 5.51 5.74 (0.27) (0.27) $27.22 26.61% 1.00% 1.00% 0.95% 0.95% 18% $135,315
2016 $21.77 0.25 (0.04) 0.21 (0.23) (0.23) $21.75 0.99% 0.99% 0.99% 1.18% 1.18% 71% $87,865
I Class
2020 $30.50 0.35 3.16 3.51 (0.06) (0.20) (0.26) $33.75 11.55% 0.59% 0.63% 1.08% 1.04% 36% $245,759
2019 $28.27 0.37 3.81 4.18 (0.28) (1.67) (1.95) $30.50 16.37% 0.60% 0.64% 1.34% 1.30% 33% $106,268
2018 $27.30 0.33 1.51 1.84 (0.26) (0.61) (0.87) $28.27 6.80% 0.75% 0.75% 1.11% 1.11% 41% $38,188
2017 $21.81 0.27 5.53 5.80 (0.31) (0.31) $27.30 26.88% 0.80% 0.80% 1.15% 1.15% 18% $19,776
2016 $21.84 0.29 (0.05) 0.24 (0.27) (0.27) $21.81 1.19% 0.79% 0.79% 1.38% 1.38% 71% $5,637
Y Class
2020 $30.56 0.43 3.12 3.55 (0.10) (0.20) (0.30) $33.81 11.70% 0.44% 0.48% 1.23% 1.19% 36% $8,115
2019 $28.32 0.41 3.82 4.23 (0.32) (1.67) (1.99) $30.56 16.56% 0.45% 0.49% 1.49% 1.45% 33% $51,037
2018 $27.33 0.36 1.52 1.88 (0.28) (0.61) (0.89) $28.32 6.93% 0.60% 0.60% 1.26% 1.26% 41% $14,485
2017(3)
$23.89 0.16 3.28 3.44 $27.33 14.40%
0.65%(4)
0.65%(4)
1.10%(4)
1.10%(4)
18%(5)
$383




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
A Class
2020 $30.29 0.21 3.13 3.34 (0.20) (0.20) $33.43 11.07% 1.04% 1.08% 0.63% 0.59% 36% $54,638
2019 $28.09 0.25 3.78 4.03 (0.16) (1.67) (1.83) $30.29 15.81% 1.05% 1.09% 0.89% 0.85% 33% $54,290
2018 $27.13 0.19 1.51 1.70 (0.13) (0.61) (0.74) $28.09 6.31% 1.20% 1.20% 0.66% 0.66% 41% $50,489
2017 $21.67 0.17 5.50 5.67 (0.21) (0.21) $27.13 26.34% 1.25% 1.25% 0.70% 0.70% 18% $51,396
2016 $21.69 0.20 (0.05) 0.15 (0.17) (0.17) $21.67 0.74% 1.24% 1.24% 0.93% 0.93% 71% $97,012
C Class
2020 $29.56 (0.02) 3.03 3.01 (0.20) (0.20) $32.37 10.22% 1.79% 1.83% (0.12)% (0.16)% 36% $10,178
2019 $27.48 0.04 3.71 3.75 (1.67) (1.67) $29.56 14.98% 1.80% 1.84% 0.14% 0.10% 33% $10,149
2018 $26.63 (0.03) 1.49 1.46 (0.61) (0.61) $27.48 5.51% 1.95% 1.95% (0.09)% (0.09)% 41% $11,277
2017 $21.27 (0.01) 5.41 5.40 (0.04) (0.04) $26.63 25.40% 2.00% 2.00% (0.05)% (0.05)% 18% $17,904
2016 $21.29 0.04 (0.04)
(6)
(0.02) (0.02) $21.27 (0.02)% 1.99% 1.99% 0.18% 0.18% 71% $18,640
R Class
2020 $30.12 0.12 3.11 3.23 (0.20) (0.20) $33.15 10.77% 1.29% 1.33% 0.38% 0.34% 36% $9,014
2019 $27.93 0.18 3.77 3.95 (0.09) (1.67) (1.76) $30.12 15.56% 1.30% 1.34% 0.64% 0.60% 33% $4,466
2018 $26.98 0.11 1.51 1.62 (0.06) (0.61) (0.67) $27.93 6.04% 1.45% 1.45% 0.41% 0.41% 41% $3,223
2017 $21.55 0.11 5.47 5.58 (0.15) (0.15) $26.98 26.03% 1.50% 1.50% 0.45% 0.45% 18% $3,910
2016 $21.58 0.14 (0.05) 0.09 (0.12) (0.12) $21.55 0.44% 1.49% 1.49% 0.68% 0.68% 71% $4,090




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Operating
Expenses
(before
expense
waiver)
Net
Investment
Income
(Loss)
Net
Investment
Income
(Loss)
(before
expense
waiver)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R5 Class
2020 $30.52 0.34 3.17 3.51 (0.06) (0.20) (0.26) $33.77 11.55% 0.59% 0.63% 1.08% 1.04% 36% $3,195
2019 $28.29 0.38 3.80 4.18 (0.28) (1.67) (1.95) $30.52 16.36% 0.60% 0.64% 1.34% 1.30% 33% $1,314
2018 $27.30 0.32 1.52 1.84 (0.24) (0.61) (0.85) $28.29 6.82% 0.75% 0.75% 1.11% 1.11% 41% $1,344
2017(3)
$23.89 0.15 3.26 3.41 $27.30 14.27%
0.80%(4)
0.80%(4)
1.07%(4)
1.07%(4)
18%(5)
$6
R6 Class
2020 $30.56 0.39 3.17 3.56 (0.08) (0.20) (0.28) $33.84 11.70% 0.44% 0.48% 1.23% 1.19% 36% $5,150
2019(7)
$28.05 0.21 2.30 2.51 $30.56 8.95%
0.44%(4)
0.49%(4)
1.18%(4)
1.13%(4)
33%(8)
$3,979
G Class
2020 $30.64 0.54 3.18 3.72 (0.19) (0.20) (0.39) $33.97 12.21%
0.00%(9)
0.48% 1.67% 1.19% 36% $1,800,919
2019(7)
$28.05 0.37 2.22 2.59 $30.64 9.23%
0.00%(4)(9)
0.49%(4)
2.04%(4)
1.55%(4)
33%(8)
$497,635




Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)April 10, 2017 (commencement of sale) through October 31, 2017.
(4)Annualized.
(5)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.
(6)Per-share amount was less than $0.005.
(7)April 1, 2019 (commencement of sale) through October 31, 2019.
(8)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2019.
(9)Ratio was less than 0.005%.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of
investments, of Sustainable Equity Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Sustainable Equity Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.


DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.

30



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
31



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
32



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





33



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
34



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the one-, three-, five-, and ten-year periods reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
35



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was below the median of the total expense ratios of the Fund’s peer expense universe.
36



The Board and the Advisor agreed to a permanent change to the Fund's fee schedule that should have the effect of lowering the Fund's annual unified management fee by approximately 0.05% (e.g., the Investor Class unified fee will be reduced from 0.84% to 0.79%), beginning August 1, 2020. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
37



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.



38



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates up to the maximum amount allowable as qualified dividend income for the fiscal year ended October 31, 2020.

For corporate taxpayers, the fund hereby designates $7,163,302, or up to the maximum amount allowable, of ordinary income distributions paid during the fiscal year ended October 31, 2020 as qualified for the corporate dividends received deduction.

The fund hereby designates $12,251,552, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.



39



Notes























































40








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Contact Us americancentury.com
Automated Information Line 1-800-345-8765
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or 816-531-5575
Investors Using Advisors 1-800-378-9878
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American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90971 2012





    


IMAGE81.JPG
Annual Report
October 31, 2020
Ultra® Fund
Investor Class (TWCUX)
I Class (TWUIX)
Y Class (AULYX)
A Class (TWUAX)
C Class (TWCCX)
R Class (AULRX)
R5 Class (AULGX)
R6 Class (AULDX)
G Class (AULNX)














Beginning on January 1, 2021, as permitted by regulations adopted by the Securities and Exchange Commission, paper copies of the fund’s shareholder reports like this one will no longer be sent by mail, unless you specifically request paper copies of the reports from the fund or from your financial intermediary, such as a broker-dealer or bank. Instead, the reports will be made available on a website, and you will be notified by mail each time a report is posted and provided with a website link to access the report.

If you already elected to receive shareholder reports electronically, you will not be affected by this change and you need not take any action. You may elect to receive shareholder reports and other communications from the fund or your financial intermediary electronically by calling or sending an email request to your appropriate contacts as listed on the back cover of this report.

You may elect to receive all future reports in paper free of charge. You can inform the fund or your financial intermediary that you wish to continue receiving paper copies of your shareholder reports by calling or sending an email request to your appropriate contacts as listed on the back cover of this report. Your election to receive reports in paper will apply to all funds held with the fund complex/your financial intermediary.









Table of Contents
 
President’s Letter
2
Performance
3
Portfolio Commentary
5
Fund Characteristics
7
Shareholder Fee Example
8
Schedule of Investments
10
Statement of Assets and Liabilities
13
Statement of Operations
14
Statement of Changes in Net Assets
15
Notes to Financial Statements
16
Financial Highlights
23
Report of Independent Registered Public Accounting Firm
27
Management
28
Approval of Management Agreement
31
Additional Information
35

















Any opinions expressed in this report reflect those of the author as of the date of the report, and do not necessarily represent the opinions of American Century Investments® or any other person in the American Century Investments organization. Any such opinions are subject to change at any time based upon market or other conditions and American Century Investments disclaims any responsibility to update such opinions. These opinions may not be relied upon as investment advice and, because investment decisions made by American Century Investments funds are based on numerous factors, may not be relied upon as an indication of trading intent on behalf of any American Century Investments fund. Security examples are used for representational purposes only and are not intended as recommendations to purchase or sell securities. Performance information for comparative indices and securities is provided to American Century Investments by third party vendors. To the best of American Century Investments’ knowledge, such information is accurate at the time of printing.




President’s Letter
IMAGE181.JPG Jonathan Thomas

Dear Investor:

Thank you for reviewing this annual report for the period ended October 31, 2020. Annual reports help convey important information about fund returns, including market factors that affected performance. For additional investment insights, please visit americancentury.com.

Pandemic Disrupted Economic, Market Courses

Market sentiment began the period relatively upbeat. A dovish Federal Reserve (Fed), modest inflation, improving economic and earnings data, and progress on U.S.-China trade policy helped boost global growth outlooks. Against this backdrop, riskier assets generally remained in favor.

However, beginning in late February, the COVID-19 outbreak rapidly spread worldwide, halting most U.S. and global economic activity and triggering a deep worldwide recession. Global stocks and credit-sensitive assets sold off sharply, while U.S. Treasury yields plunged to record lows amid soaring demand. Quick and aggressive action from the Fed and other central banks and federal governments helped stabilize and restore confidence in the financial markets. By summer, declining coronavirus infection and death rates in many regions and the reopening of economies were positive influences. By the end of the reporting period, most data suggested an economic recovery was underway. But, at the same time, COVID-19 infection rates were rising in the U.S. and Europe, prompting new lockdown measures in some European countries.

Overall, the broad U.S. stock market overcame the effects of the early 2020 sell-off to deliver a solid gain for the 12-month period. Growth stocks rallied and significantly outperformed value stocks, which generally declined. Global bond returns were broadly positive, as yields declined.

Science Helps Steer the Return to Normal

The return to pre-pandemic life will take time and patience, but we are confident we will get there. The first COVID-19 vaccine is on track for approval by year-end, and medical professionals continue to fine-tune virus treatment protocols. In the meantime, investors likely will face periods of outbreak-related disruptions, economic and political uncertainty, and heightened market volatility. These influences can be unsettling, but they tend to be temporary.

We appreciate your confidence in us during these extraordinary times. Our firm has a long history of helping clients weather unpredictable markets, and we’re confident we will continue to meet today’s challenges.

Sincerely,
IMAGE191.JPG
Jonathan Thomas
President and Chief Executive Officer
American Century Investments
2



Performance
Total Returns as of October 31, 2020
      Average Annual Returns  
  Ticker
Symbol
1 year 5 years 10 years Since
Inception
Inception
Date
Investor Class TWCUX 37.77% 18.30% 16.69% 11/2/81
Russell 1000 Growth Index 29.22% 17.30% 16.29%
S&P 500 Index 9.71% 11.70% 13.00%
I Class TWUIX 38.05% 18.53% 16.93% 11/14/96
Y Class AULYX 38.26% 23.20% 4/10/17
A Class TWUAX 10/2/96
No sales charge 37.43% 18.00% 16.40%
With sales charge 29.52% 16.62% 15.71%
C Class TWCCX 36.39% 17.12% 15.53% 10/29/01
R Class AULRX 37.08% 17.70% 16.11% 8/29/03
R5 Class AULGX 38.05% 23.01% 4/10/17
R6 Class AULDX 38.26% 18.71% 17.81% 7/26/13
G Class AULNX 39.09% 32.50% 8/1/19
Average annual returns since inception are presented when ten years of performance history is not available.
Fund returns would have been lower if a portion of the fees had not been waived. Extraordinary performance is attributable in part to unusually favorable market conditions and may not be repeated or consistently achieved in the future.

Sales charges include initial sales charges and contingent deferred sales charges (CDSCs), as applicable. A Class shares have a 5.75% maximum initial sales charge and may be subject to a maximum CDSC of 1.00%. C Class shares redeemed within 12 months of purchase are subject to a maximum CDSC of 1.00%. The SEC requires that mutual funds provide performance information net of maximum sales charges in all cases where charges could be applied.














Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
3



Growth of $10,000 Over 10 Years
$10,000 investment made October 31, 2010
Performance for other share classes will vary due to differences in fee structure.
  CHART-98139DEEC8D247359C31.JPG
Value on October 31, 2020
Investor Class — $46,863
Russell 1000 Growth Index — $45,290
S&P 500 Index — $33,987

Total Annual Fund Operating Expenses
Investor Class I Class Y Class A Class C Class R Class R5 Class R6 Class G Class
0.97% 0.77% 0.62% 1.22% 1.97% 1.47% 0.77% 0.62% 0.62%
The total annual fund operating expenses shown is as stated in the fund’s prospectus current as of the date of this report. The prospectus may vary from the expense ratio shown elsewhere in this report because it is based on a different time period, includes acquired fund fees and expenses, and, if applicable, does not include fee waivers or expense reimbursements.















Data presented reflect past performance. Past performance is no guarantee of future results. Current performance may be higher or lower than the performance shown. Total returns for periods less than one year are not annualized. Investment return and principal value will fluctuate, and redemption value may be more or less than original cost. Data assumes reinvestment of dividends and capital gains, and none of the charts reflect the deduction of taxes that a shareholder would pay on fund distributions or the redemption of fund shares. To obtain performance data current to the most recent month end, please call 1-800-345-2021 or visit americancentury.com. For additional information about the fund, please consult the prospectus.
4



Portfolio Commentary
 
Portfolio Managers: Keith Lee, Michael Li and Jeff Bourke

Performance Summary

Ultra returned 37.77%* for the 12 months ended October 31, 2020, outpacing the 29.22% return of the fund’s benchmark, the Russell 1000 Growth Index.

U.S. stocks delivered strong returns during the reporting period, which was marked by extreme volatility. Stocks initially rose to all-time highs in February, before the COVID-19 pandemic and measures to combat it led to the first recession and bear market in stocks since the 2008-09 financial crisis. Massive monetary and fiscal stimulus helped support the economy and markets, and stocks recovered the ground lost earlier. Within the Russell 1000 Growth Index, consumer discretionary and information technology led the benchmark’s performance. At the other end of the spectrum, the energy sector struggled with the declining price of oil amid a sharp slowdown in economic growth and falling energy demand.

Stock selection in the consumer discretionary sector contributed most to outperformance relative to the benchmark. Stock decisions in the information technology sector were also helpful. An overweight allocation to energy detracted fractionally from relative performance.

Consumer Discretionary Stocks Were Top Contributors

The automobiles industry led outperformance in the consumer discretionary sector. The leading contribution to relative performance came from electric car company Tesla, which benefited from solid fundamental reports and strong demand for its vehicles. The company reported better-than-expected production numbers, successfully launched the Model Y and announced plans to ramp up production of its commercial Tesla Semi.

In the information technology sector, DocuSign was a key contributor. The cloud-based electronic signature company outperformed as e-signatures and digital document management have become increasingly mainstream. The stock is benefiting from a secular trend toward spending on productivity-enhancement tools. Canada-based e-commerce firm Shopify outperformed after reporting record earnings. The company also announced a partnership with Walmart, which could boost sales. Square was a top performer on optimism about continued growth trends in its cash app business and its merchant-based business showing signs of stabilizing after being negatively impacted by the COVID-19 virus.

Regeneron Pharmaceuticals was another major contributor to outperformance. The biotechnology company is engaged in the discovery and development of medicines for the treatment of serious diseases, and it maintains one of the world’s most comprehensive genetic databases. Regeneron’s treatment for COVID-19 patients showed benefits in late-stage clinical trials.

Energy Holdings Detracted Fractionally from Performance

We have only one holding in the energy sector. EOG Resources detracted as the stock price of this leading oil and gas exploration and production company fell along with the price of crude oil amid weakening demand due to the pandemic.





*All fund returns referenced in this commentary are for Investor Class shares. Performance for other share classes will vary due to differences in fee structure; when Investor Class performance exceeds that of the fund’s benchmark, other share classes may not. See page 3 for returns for all share classes.
5



Elsewhere, among other individual detractors from relative performance was chipmaker NVIDIA. We did not own the stock, which is a benchmark component. The company reported strong results and raised guidance due to strength in its data center and gaming businesses. Digital payment companies Mastercard and Visa underperformed as transaction volumes declined along with economic activity. Revenues declined further because of weakness in cross-border transactions as a result of pandemic-related travel restrictions.

The stock of The TJX Cos. underperformed as the off-price retailer temporarily closed its stores due to the pandemic. We like the long-term prospects for TJX as traditional mall retailers close their shops and consumers look for value.

Outlook

We remain confident in our belief that high-quality companies with a capability for sustained long-term growth can outperform over time. Our portfolio positioning reflects where we are finding stocks of what we believe are attractive, well-run companies as a result of the application of that philosophy and process.

As of October 31, 2020, the largest sector overweights relative to the benchmark were in the communication services and consumer discretionary sectors. The communication services sector encompasses entertainment and communication stocks, including large portfolio holdings Facebook and Google parent Alphabet. We believe our consumer discretionary companies with dominant global brands or which are leveraging technology to drive expansion offer attractive, sustainable growth going forward. In particular, we see many companies in the sector benefiting from digital transformation and online growth of their business.

The portfolio’s largest underweight was in the health care sector. Although the portfolio has lighter exposure than the benchmark, we believe that many segments of the health care industry are primed for a golden age of innovation and positive social impact. Indeed, we think select companies in the sector are uniquely positioned to address a number of profound social and medical problems. The sector’s rapid, effective response to the pandemic is important proof of this concept. Our information technology holdings were modestly underweight relative to the benchmark. However, the sector represented our largest absolute position. We continued to find an abundance of what we believe are high-quality, well-run companies benefiting from powerful secular trends.



6



Fund Characteristics
OCTOBER 31, 2020
Top Ten Holdings % of net assets
Apple, Inc. 12.0%
Amazon.com, Inc. 8.3%
Alphabet, Inc.* 6.5%
Microsoft Corp. 5.7%
Facebook, Inc., Class A 4.5%
Mastercard, Inc., Class A 4.3%
Visa, Inc., Class A 4.1%
salesforce.com, Inc. 3.6%
UnitedHealth Group, Inc. 3.3%
Tesla, Inc. 3.1%
*Includes all classes of the issuer held by the fund.
Top Five Industries % of net assets
IT Services 14.9%
Software 13.7%
Technology Hardware, Storage and Peripherals 12.0%
Interactive Media and Services 11.9%
Internet and Direct Marketing Retail 8.3%
Types of Investments in Portfolio % of net assets
Common Stocks 100.0%
Temporary Cash Investments
—*
Other Assets and Liabilities
—*
*Category is less than 0.05% of total net assets.

7



Shareholder Fee Example 

Fund shareholders may incur two types of costs: (1) transaction costs, including sales charges (loads) on purchase payments and redemption/exchange fees; and (2) ongoing costs, including management fees; distribution and service (12b-1) fees; and other fund expenses. This example is intended to help you understand your ongoing costs (in dollars) of investing in your fund and to compare these costs with the ongoing cost of investing in other mutual funds.

The example is based on an investment of $1,000 made at the beginning of the period and held for the entire period from May 1, 2020 to October 31, 2020.

Actual Expenses

The table provides information about actual account values and actual expenses for each class. You may use the information, together with the amount you invested, to estimate the expenses that you paid over the period. First, identify the share class you own. Then simply divide your account value by $1,000 (for example, an $8,600 account value divided by $1,000 = 8.6), then multiply the result by the number under the heading “Expenses Paid During Period” to estimate the expenses you paid on your account during this period.

If you hold Investor Class shares of any American Century Investments fund, or I Class shares of the American Century Diversified Bond Fund, in an American Century Investments account (i.e., not through a financial intermediary or employer-sponsored retirement plan account), American Century Investments may charge you a $25.00 annual account maintenance fee if the value of those shares is less than $10,000. We will redeem shares automatically in one of your accounts to pay the $25.00 fee. In determining your total eligible investment amount, we will include your investments in all personal accounts (including American Century Investments brokerage accounts) registered under your Social Security number. Personal accounts include individual accounts, joint accounts, UGMA/UTMA accounts, personal trusts, Coverdell Education Savings Accounts and IRAs (including traditional, Roth, Rollover, SEP-, SARSEP- and SIMPLE-IRAs), and certain other retirement accounts. If you have only business, business retirement, employer-sponsored or American Century Investments brokerage accounts, you are currently not subject to this fee. If you are subject to the account maintenance fee, your account value could be reduced by the fee amount.

Hypothetical Example for Comparison Purposes

The table also provides information about hypothetical account values and hypothetical expenses based on the actual expense ratio of each class of your fund and an assumed rate of return of 5% per year before expenses, which is not the actual return of a fund’s share class. The hypothetical account values and expenses may not be used to estimate the actual ending account balance or expenses you paid for the period. You may use this information to compare the ongoing costs of investing in your fund and other funds. To do so, compare this 5% hypothetical example with the 5% hypothetical examples that appear in the shareholder reports of the other funds.

Please note that the expenses shown in the table are meant to highlight your ongoing costs only and do not reflect any transactional costs, such as sales charges (loads) or redemption/exchange fees. Therefore, the table is useful in comparing ongoing costs only, and will not help you determine the relative total costs of owning different funds. In addition, if these transactional costs were included, your costs would have been higher.

8




Beginning
Account Value
5/1/20
Ending
Account Value
10/31/20
Expenses Paid
During Period(1)
5/1/20 - 10/31/20

Annualized
Expense Ratio(1)
Actual
Investor Class $1,000 $1,263.40 $5.46 0.96%
I Class $1,000 $1,264.80 $4.33 0.76%
Y Class $1,000 $1,265.70 $3.47 0.61%
A Class $1,000 $1,261.80 $6.88 1.21%
C Class $1,000 $1,257.20 $11.12 1.96%
R Class $1,000 $1,260.30 $8.30 1.46%
R5 Class $1,000 $1,264.60 $4.33 0.76%
R6 Class $1,000 $1,265.70 $3.47 0.61%
G Class $1,000 $1,269.50 $0.00
0.00%(2)
Hypothetical
Investor Class $1,000 $1,020.31 $4.88 0.96%
I Class $1,000 $1,021.32 $3.86 0.76%
Y Class $1,000 $1,022.07 $3.10 0.61%
A Class $1,000 $1,019.05 $6.14 1.21%
C Class $1,000 $1,015.28 $9.93 1.96%
R Class $1,000 $1,017.80 $7.41 1.46%
R5 Class $1,000 $1,021.32 $3.86 0.76%
R6 Class $1,000 $1,022.07 $3.10 0.61%
G Class $1,000 $1,025.14 $0.00
0.00%(2)
(1)Expenses are equal to the class's annualized expense ratio listed in the table above, multiplied by the average account value over the period, multiplied by 184, the number of days in the most recent fiscal half-year, divided by 366, to reflect the one-half year period. Annualized expense ratio reflects actual expenses, including any applicable fee waivers or expense reimbursements and excluding any acquired fund fees and expenses.
(2)Other expenses, which include directors' fees and expenses, did not exceed 0.005%.

9



Schedule of Investments

OCTOBER 31, 2020
Shares Value
COMMON STOCKS — 100.0%
Automobiles — 3.1%
Tesla, Inc.(1)
1,260,000  $ 488,930,400 
Banks — 0.9%
JPMorgan Chase & Co. 1,032,435  101,219,927 
U.S. Bancorp 1,116,000  43,468,200 
144,688,127 
Beverages — 1.0%
Constellation Brands, Inc., Class A 936,673  154,766,480 
Biotechnology — 2.7%
Biogen, Inc.(1)
424,944  107,115,634 
Ionis Pharmaceuticals, Inc.(1)
731,088  34,324,582 
Regeneron Pharmaceuticals, Inc.(1)
537,000  291,891,720 
433,331,936 
Capital Markets — 1.1%
MSCI, Inc. 491,778  172,043,615 
Chemicals — 0.6%
Ecolab, Inc. 496,000  91,060,640 
Commercial Services and Supplies — 0.4%
Copart, Inc.(1)
508,736  56,144,105 
Electrical Equipment — 0.6%
Acuity Brands, Inc. 409,000  36,458,260 
Rockwell Automation, Inc. 275,000  65,208,000 
101,666,260 
Electronic Equipment, Instruments and Components — 0.7%
Cognex Corp. 700,000  46,130,000 
Keyence Corp. 127,900  57,999,220 
104,129,220 
Entertainment — 2.7%
Netflix, Inc.(1)
536,667  255,313,959 
Roku, Inc.(1)
284,000  57,481,600 
Walt Disney Co. (The) 1,035,000  125,493,750 
438,289,309 
Food and Staples Retailing — 1.8%
Costco Wholesale Corp. 802,820  287,104,488 
Health Care Equipment and Supplies — 5.3%
ABIOMED, Inc.(1)
103,743  26,130,787 
DexCom, Inc.(1)
237,000  75,740,460 
Edwards Lifesciences Corp.(1)
2,238,438  160,473,620 
IDEXX Laboratories, Inc.(1)
313,000  132,968,660 
Intuitive Surgical, Inc.(1)
608,810  406,124,975 
Tandem Diabetes Care, Inc.(1)
380,056  41,426,104 
842,864,606 
Health Care Providers and Services — 3.3%
UnitedHealth Group, Inc. 1,728,000  527,281,920 
Hotels, Restaurants and Leisure — 3.4%
Chipotle Mexican Grill, Inc.(1)
242,398  291,236,349 
Starbucks Corp. 2,189,000  190,355,440 
10



Shares Value
Wingstop, Inc. 592,000  $ 68,867,360 
550,459,149 
Household Products — 0.8%
Colgate-Palmolive Co. 1,677,000  132,298,530 
Interactive Media and Services — 11.9%
Alphabet, Inc., Class A(1)
288,955  466,983,065 
Alphabet, Inc., Class C(1)
351,787  570,250,245 
Facebook, Inc., Class A(1)
2,746,176  722,546,367 
Tencent Holdings Ltd. 1,877,000  143,977,961 
1,903,757,638 
Internet and Direct Marketing Retail — 8.3%
Amazon.com, Inc.(1)
436,294  1,324,654,028 
IT Services — 14.9%
Adyen NV(1)
55,000  92,810,829 
Mastercard, Inc., Class A 2,392,700  690,628,928 
PayPal Holdings, Inc.(1)
2,528,716  470,669,909 
Shopify, Inc., Class A(1)
220,453  204,013,820 
Square, Inc., Class A(1)
1,742,670  269,904,729 
Visa, Inc., Class A 3,592,544  652,801,170 
2,380,829,385 
Machinery — 1.6%
Donaldson Co., Inc. 704,557  33,466,458 
Nordson Corp. 322,200  62,323,146 
Westinghouse Air Brake Technologies Corp. 1,365,607  80,980,495 
Yaskawa Electric Corp. 1,951,800  75,950,501 
252,720,600 
Oil, Gas and Consumable Fuels — 0.2%
EOG Resources, Inc. 847,000  29,001,280 
Personal Products — 1.3%
Estee Lauder Cos., Inc. (The), Class A 961,000  211,093,260 
Road and Rail — 0.9%
J.B. Hunt Transport Services, Inc. 1,205,000  146,696,700 
Semiconductors and Semiconductor Equipment — 2.3%
Analog Devices, Inc. 1,258,000  149,110,740 
Applied Materials, Inc. 1,566,108  92,760,577 
Xilinx, Inc. 1,090,291  129,406,639 
371,277,956 
Software — 13.7%
DocuSign, Inc.(1)
1,465,000  296,296,250 
Fair Isaac Corp.(1)
179,000  70,069,550 
Microsoft Corp. 4,520,765  915,319,289 
Paycom Software, Inc.(1)
312,000  113,596,080 
salesforce.com, Inc.(1)
2,508,766  582,711,079 
Splunk, Inc.(1)
373,000  73,868,920 
Zoom Video Communications, Inc., Class A(1)
284,000  130,898,440 
2,182,759,608 
Specialty Retail — 2.3%
Ross Stores, Inc. 1,430,729  121,855,189 
TJX Cos., Inc. (The) 4,939,724  250,937,979 
372,793,168 
Technology Hardware, Storage and Peripherals — 12.0%
Apple, Inc. 17,668,492  1,923,392,039 
11



Shares Value
Textiles, Apparel and Luxury Goods — 2.2%
lululemon athletica, Inc.(1)
208,482  $ 66,566,218 
NIKE, Inc., Class B 2,302,000  276,424,160 
342,990,378 
TOTAL COMMON STOCKS
(Cost $4,455,798,760)
15,967,024,825 
TEMPORARY CASH INVESTMENTS
Repurchase Agreement, BMO Capital Markets Corp., (collateralized by various U.S. Treasury obligations, 0.50% - 3.375%,
6/30/21 - 11/15/48, valued at $1,208,998), in a joint trading account at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $1,189,478)
1,189,472 
Repurchase Agreement, Fixed Income Clearing Corp., (collateralized by various U.S. Treasury obligations, 3.625%, 2/15/44, valued at $2,112,532), at 0.06%, dated 10/30/20, due 11/2/20 (Delivery value $2,071,010) 2,071,000 
TOTAL TEMPORARY CASH INVESTMENTS
(Cost $3,260,472)
3,260,472 
TOTAL INVESTMENT SECURITIES — 100.0%
(Cost $4,459,059,232)
15,970,285,297 
OTHER ASSETS AND LIABILITIES
(2,722,370)
TOTAL NET ASSETS — 100.0% $ 15,967,562,927 

FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS
Currency Purchased Currency Sold Counterparty Settlement Date Unrealized Appreciation
(Depreciation)
EUR 2,109,250 USD 2,475,819 Credit Suisse AG 12/31/20 $ (15,700)
EUR 1,859,000 USD 2,210,555 Credit Suisse AG 12/31/20 (42,315)
EUR 1,859,000 USD 2,202,008 Credit Suisse AG 12/31/20 (33,768)
USD 63,910,182 EUR 54,447,250 Credit Suisse AG 12/31/20 405,770 
USD 2,149,882 EUR 1,841,125 Credit Suisse AG 12/31/20 2,490 
USD 2,334,081 EUR 1,984,125 Credit Suisse AG 12/31/20 19,902 
USD 3,107,445 EUR 2,627,625 Credit Suisse AG 12/31/20 42,721 
USD 45,209,238 JPY 4,743,014,150 Bank of America N.A. 12/30/20 (133,486)
USD 2,727,655 JPY 288,011,150 Bank of America N.A. 12/30/20 (25,702)
$ 219,912 

NOTES TO SCHEDULE OF INVESTMENTS
EUR - Euro
JPY - Japanese Yen
USD - United States Dollar
†    Category is less than 0.05% of total net assets.
(1)Non-income producing.


See Notes to Financial Statements.
12



Statement of Assets and Liabilities
OCTOBER 31, 2020
Assets
Investment securities, at value (cost of $4,459,059,232) $ 15,970,285,297 
Receivable for investments sold 15,585,497 
Receivable for capital shares sold 6,080,728 
Unrealized appreciation on forward foreign currency exchange contracts 470,883 
Dividends and interest receivable 3,562,297 
Securities lending receivable 19,201 
15,996,003,903 
Liabilities
Disbursements in excess of demand deposit cash 117 
Payable for capital shares redeemed 14,625,738 
Unrealized depreciation on forward foreign currency exchange contracts 250,971 
Accrued management fees 13,491,823 
Distribution and service fees payable 72,327 
28,440,976 
Net Assets $ 15,967,562,927 
Net Assets Consist of:
Capital (par value and paid-in surplus) $ 4,010,075,511 
Distributable earnings 11,957,487,416 
$ 15,967,562,927 

Net Assets Shares Outstanding Net Asset Value
Per Share
Investor Class, $0.01 Par Value $14,648,924,593 220,687,212 $66.38
I Class, $0.01 Par Value $588,450,910 8,497,876 $69.25
Y Class, $0.01 Par Value $1,707,541 24,538 $69.59
A Class, $0.01 Par Value $167,682,336 2,669,640 $62.81*
C Class, $0.01 Par Value $24,319,704 474,702 $51.23
R Class, $0.01 Par Value $26,729,177 440,901 $60.62
R5 Class, $0.01 Par Value $257,846 3,721 $69.29
R6 Class, $0.01 Par Value $509,483,676 7,329,751 $69.51
G Class, $0.01 Par Value $7,144 102 $70.04
*Maximum offering price $66.64 (net asset value divided by 0.9425).


See Notes to Financial Statements.
13



Statement of Operations
YEAR ENDED OCTOBER 31, 2020
Investment Income (Loss)
Income:
Dividends (net of foreign taxes withheld of $92,608) $ 85,123,109 
Interest 292,923 
Securities lending, net 19,201 
85,435,233 
Expenses:
Management fees 133,143,519 
Distribution and service fees:
A Class 348,326 
C Class 205,353 
R Class 109,874 
Directors' fees and expenses 450,125 
Other expenses 1,208 
134,258,405 
Fees waived - G Class (37)
134,258,368 
Net investment income (loss) (48,823,135)
Realized and Unrealized Gain (Loss)
Net realized gain (loss) on:
Investment transactions (Note 4) 525,996,155 
Forward foreign currency exchange contract transactions (2,337,508)
Foreign currency translation transactions 16,793 
523,675,440 
Change in net unrealized appreciation (depreciation) on:
Investments 3,982,877,671 
Forward foreign currency exchange contracts 180,160 
Translation of assets and liabilities in foreign currencies 7,288 
3,983,065,119 
Net realized and unrealized gain (loss) 4,506,740,559 
Net Increase (Decrease) in Net Assets Resulting from Operations $ 4,457,917,424 


See Notes to Financial Statements.
14



Statement of Changes in Net Assets
YEARS ENDED OCTOBER 31, 2020 AND OCTOBER 31, 2019
Increase (Decrease) in Net Assets October 31, 2020 October 31, 2019
Operations
Net investment income (loss) $ (48,823,135) $ (14,151,682)
Net realized gain (loss) 523,675,440  652,663,454 
Change in net unrealized appreciation (depreciation) 3,983,065,119  899,393,859 
Net increase (decrease) in net assets resulting from operations 4,457,917,424  1,537,905,631 
Distributions to Shareholders
From earnings:
Investor Class (497,939,761) (730,083,401)
I Class (15,792,365) (28,348,100)
Y Class (53,531) (76,346)
A Class (5,351,781) (7,623,683)
C Class (935,790) (947,855)
R Class (850,029) (1,360,937)
R5 Class (4,210) (448)
R6 Class (16,454,953) (25,190,411)
G Class (217) — 
Decrease in net assets from distributions (537,382,637) (793,631,181)
Capital Share Transactions
Net increase (decrease) in net assets from capital share transactions (Note 5) (240,034,647) 116,179,202 
Net increase (decrease) in net assets 3,680,500,140  860,453,652 
Net Assets
Beginning of period 12,287,062,787  11,426,609,135 
End of period $ 15,967,562,927  $ 12,287,062,787 


See Notes to Financial Statements.
15



Notes to Financial Statements

OCTOBER 31, 2020

1. Organization

American Century Mutual Funds, Inc. (the corporation) is registered under the Investment Company Act of 1940, as amended (the 1940 Act), as an open-end management investment company and is organized as a Maryland corporation. Ultra Fund (the fund) is one fund in a series issued by the corporation. The fund's investment objective is to seek long-term capital growth.

The fund offers the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class. The A Class may incur an initial sales charge. The A Class and C Class may be subject to a contingent deferred sales charge. Sale of the G Class commenced on August 1, 2019.

2. Significant Accounting Policies

The following is a summary of significant accounting policies consistently followed by the fund in preparation of its financial statements. The fund is an investment company and follows accounting and reporting guidance in accordance with accounting principles generally accepted in the United States of America. This may require management to make certain estimates and assumptions at the date of the financial statements. Actual results could differ from these estimates. Management evaluated the impact of events or transactions occurring through the date the financial statements were issued that would merit recognition or disclosure.

Investment Valuations — The fund determines the fair value of its investments and computes its net asset value per share at the close of regular trading (usually 4 p.m. Eastern time) on the New York Stock Exchange (NYSE) on each day the NYSE is open. The Board of Directors has adopted valuation policies and procedures to guide the investment advisor in the fund’s investment valuation process and to provide methodologies for the oversight of the fund’s pricing function.

Equity securities that are listed or traded on a domestic securities exchange are valued at the last reported sales price or at the official closing price as provided by the exchange. Equity securities traded on foreign securities exchanges are generally valued at the closing price of such securities on the exchange where primarily traded or at the close of the NYSE, if that is earlier. If no last sales price is reported, or if local convention or regulation so provides, the mean of the latest bid and asked prices may be used. Securities traded over-the-counter are valued at the mean of the latest bid and asked prices, the last sales price, or the official closing price. Equity securities initially expressed in local currencies are translated into U.S. dollars at the mean of the appropriate currency exchange rate at the close of the NYSE as provided by an independent pricing service.

Fixed income securities are valued at the evaluated mean as provided by independent pricing services or at the mean of the most recent bid and asked prices as provided by investment dealers. U.S. Treasury and Government Agency securities are valued using market models that consider trade data, quotations from dealers and active market makers, relevant yield curve and spread data, creditworthiness, trade data or market information on comparable securities, and other relevant security specific information.

Open-end management investment companies are valued at the reported net asset value per share. Repurchase agreements are valued at cost, which approximates fair value. Forward foreign currency exchange contracts are valued at the mean of the appropriate forward exchange rate at the close of the NYSE as provided by an independent pricing service.

If the fund determines that the market price for an investment is not readily available or the valuation methods mentioned above do not reflect an investment’s fair value, such investment is valued as determined in good faith by the Board of Directors or its delegate, in accordance with policies and procedures adopted by the Board of Directors. In its determination of fair value, the fund may review several factors including, but not limited to, market information regarding the specific investment or comparable investments and correlation with other investment types, futures indices or general market indicators. Circumstances that may cause the fund to use these procedures to value an investment include, but are not limited to: an investment has been declared in default or is distressed; trading in a security has been suspended during the trading day or a security is not actively trading on its principal exchange; prices received from a regular pricing source are deemed unreliable; or there is a foreign market holiday and no trading occurred.
16



The fund monitors for significant events occurring after the close of an investment’s primary exchange but before the fund’s net asset value per share is determined. Significant events may include, but are not limited to: corporate announcements and transactions; governmental action and political unrest that could impact a specific investment or an investment sector; or armed conflicts, natural disasters and similar events that could affect investments in a specific country or region. The fund also monitors for significant fluctuations between domestic and foreign markets, as evidenced by the U.S. market or such other indicators that the Board of Directors, or its delegate, deems appropriate. The fund may apply a model-derived factor to the closing price of equity securities traded on foreign securities exchanges. The factor is based on observable market data as provided by an independent pricing service.

Security Transactions — Security transactions are accounted for as of the trade date. Net realized gains and losses are determined on the identified cost basis, which is also used for federal income tax purposes.

Investment Income — Dividend income less foreign taxes withheld, if any, is recorded as of the ex-dividend date. Distributions received on securities that represent a return of capital or long-term capital gain are recorded as a reduction of cost of investments and/or as a realized gain. The fund may estimate the components of distributions received that may be considered nontaxable distributions or long-term capital gain distributions for income tax purposes. Interest income is recorded on the accrual basis and includes accretion of discounts and amortization of premiums. Securities lending income is net of fees and rebates earned by the lending agent for its services.

Foreign Currency Translations — All assets and liabilities initially expressed in foreign currencies are translated into U.S. dollars at prevailing exchange rates at period end. The fund may enter into spot foreign currency exchange contracts to facilitate transactions denominated in a foreign currency. Purchases and sales of investment securities, dividend and interest income, spot foreign currency exchange contracts, and expenses are translated at the rates of exchange prevailing on the respective dates of such transactions. Net realized and unrealized foreign currency exchange gains or losses related to investment securities are a component of net realized gain (loss) on investment transactions and change in net unrealized appreciation (depreciation) on investments, respectively.

Repurchase Agreements — The fund may enter into repurchase agreements with institutions that American Century Investment Management, Inc. (ACIM) (the investment advisor) has determined are creditworthy pursuant to criteria adopted by the Board of Directors. The fund requires that the collateral, represented by securities, received in a repurchase transaction be transferred to the custodian in a manner sufficient to enable the fund to obtain those securities in the event of a default under the repurchase agreement. ACIM monitors, on a daily basis, the securities transferred to ensure the value, including accrued interest, of the securities under each repurchase agreement is equal to or greater than amounts owed to the fund under each repurchase agreement.

Joint Trading Account — Pursuant to an Exemptive Order issued by the Securities and Exchange Commission, the fund, along with certain other funds in the American Century Investments family of funds, may transfer uninvested cash balances into a joint trading account. These balances are invested in one or more repurchase agreements that are collateralized by U.S. Treasury or Agency obligations.

Segregated Assets — In accordance with the 1940 Act, the fund segregates assets on its books and records to cover certain types of investment securities and other financial instruments. ACIM monitors, on a daily basis, the securities segregated to ensure the fund designates a sufficient amount of liquid assets, marked-to-market daily. The fund may also receive assets or be required to pledge assets at the custodian bank or with a broker for collateral requirements.

Income Tax Status — It is the fund’s policy to distribute substantially all net investment income and net realized gains to shareholders and to otherwise qualify as a regulated investment company under provisions of the Internal Revenue Code. Accordingly, no provision has been made for income taxes. The fund files U.S. federal, state, local and non-U.S. tax returns as applicable. The fund's tax returns are subject to examination by the relevant taxing authority until expiration of the applicable statute of limitations, which is generally three years from the date of filing but can be longer in certain jurisdictions. At this time, management believes there are no uncertain tax positions which, based on their technical merit, would not be sustained upon examination and for which it is reasonably possible that the total amounts of unrecognized tax benefits will significantly change in the next twelve months.




17



Multiple Class — All shares of the fund represent an equal pro rata interest in the net assets of the class to which such shares belong, and have identical voting, dividend, liquidation and other rights and the same terms and conditions, except for class specific expenses and exclusive rights to vote on matters affecting only individual classes. Income, non-class specific expenses, and realized and unrealized capital gains and losses of the fund are allocated to each class of shares based on their relative net assets.

Distributions to Shareholders — Distributions from net investment income and net realized gains, if any, are generally declared and paid annually.

Indemnifications — Under the corporation’s organizational documents, its officers and directors are indemnified against certain liabilities arising out of the performance of their duties to the fund. In addition, in the normal course of business, the fund enters into contracts that provide general indemnifications. The maximum exposure under these arrangements is unknown as this would involve future claims that may be made against a fund. The risk of material loss from such claims is considered by management to be remote.

Securities Lending — Securities are lent to qualified financial institutions and brokers. State Street Bank & Trust Co. serves as securities lending agent to the fund pursuant to a Securities Lending Agreement. The lending of securities exposes the fund to risks such as: the borrowers may fail to return the loaned securities, the borrowers may not be able to provide additional collateral, the fund may experience delays in recovery of the loaned securities or delays in access to collateral, or the fund may experience losses related to the investment collateral. To minimize certain risks, loan counterparties pledge collateral in the form of cash and/or securities. The lending agent has agreed to indemnify the fund in the case of default of any securities borrowed. Cash collateral received is invested in the State Street Navigator Securities Lending Government Money Market Portfolio, a money market mutual fund registered under the 1940 Act. The loans may also be secured by U.S. government securities in an amount at least equal to the market value of the securities loaned, plus accrued interest and dividends, determined on a daily basis and adjusted accordingly. By lending securities, the fund seeks to increase its net investment income through the receipt of interest and fees. Such income is reflected separately within the Statement of Operations. The value of loaned securities and related collateral outstanding at period end, if any, are shown on a gross basis within the Schedule of Investments and Statement of Assets and Liabilities.

3. Fees and Transactions with Related Parties

Certain officers and directors of the corporation are also officers and/or directors of American Century Companies, Inc. (ACC). The corporation’s investment advisor, ACIM, the corporation's distributor, American Century Investment Services, Inc. (ACIS), and the corporation’s transfer agent, American Century Services, LLC, are wholly owned, directly or indirectly, by ACC.

Management Fees — The corporation has entered into a management agreement with ACIM, under which ACIM provides the fund with investment advisory and management services in exchange for a single, unified management fee (the fee) per class. The agreement provides that ACIM will pay all expenses of managing and operating the fund, except brokerage expenses, taxes, interest, fees and expenses of the independent directors (including legal counsel fees), extraordinary expenses, and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the 1940 Act. The fee is computed and accrued daily based on each class's daily net assets and paid monthly in arrears. The difference in the fee among the classes is a result of their separate arrangements for non-Rule 12b-1 shareholder services. It is not the result of any difference in advisory or custodial fees or other expenses related to the management of the fund’s assets, which do not vary by class. The rate of the fee is determined by applying a fee rate calculation formula. This formula takes into account the fund’s assets as well as certain assets, if any, of other clients of the investment advisor outside the American Century Investments family of funds (such as subadvised funds and separate accounts) that use very similar investment teams and strategies (strategy assets). The investment advisor agreed to waive the G Class's management fee in its entirety. The investment advisor expects this waiver to remain in effect permanently and cannot terminate it without the approval of the Board of Directors.

18



The management fee schedule range and the effective annual management fee for each class for the period ended October 31, 2020 are as follows:
Management Fee
Schedule Range
Effective Annual Management Fee
Investor Class
0.800% to 0.990% 0.96%
I Class
0.600% to 0.790% 0.76%
Y Class
0.450% to 0.640% 0.61%
A Class
0.800% to 0.990% 0.96%
C Class
0.800% to 0.990% 0.96%
R Class
0.800% to 0.990% 0.96%
R5 Class
0.600% to 0.790% 0.76%
R6 Class
0.450% to 0.640% 0.61%
G Class
0.450% to 0.640%
0.00%(1)
(1)Effective annual management fee before waiver was 0.61%.

Distribution and Service Fees — The Board of Directors has adopted a separate Master Distribution and Individual Shareholder Services Plan for each of the A Class, C Class and R Class (collectively the plans), pursuant to Rule 12b-1 of the 1940 Act. The plans provide that the A Class will pay ACIS an annual distribution and service fee of 0.25%. The plans provide that the C Class will pay ACIS an annual distribution and service fee of 1.00%, of which 0.25% is paid for individual shareholder services and 0.75% is paid for distribution services. The plans provide that the R Class will pay ACIS an annual distribution and service fee of 0.50%. The fees are computed and accrued daily based on each class’s daily net assets and paid monthly in arrears. The fees are used to pay financial intermediaries for distribution and individual shareholder services. Fees incurred under the plans during the period ended October 31, 2020 are detailed in the Statement of Operations.

Directors' Fees and Expenses — The Board of Directors is responsible for overseeing the investment advisor’s management and operations of the fund. The directors receive detailed information about the fund and its investment advisor regularly throughout the year, and meet at least quarterly with management of the investment advisor to review reports about fund operations. The fund’s officers do not receive compensation from the fund.

Interfund Transactions — The fund may enter into security transactions with other American Century Investments funds and other client accounts of the investment advisor, in accordance with the 1940 Act rules and procedures adopted by the Board of Directors. The rules and procedures require, among other things, that these transactions be effected at the independent current market price of the security. During the period, the interfund purchases and sales were $6,986,160 and $5,529,333, respectively. The effect of interfund transactions on the Statement of Operations was $(370,185) in net realized gain (loss) on investment transactions.

4. Investment Transactions

Purchases and sales of investment securities, excluding short-term investments and in kind transactions, for the period ended October 31, 2020 were $812,029,510 and $1,484,842,878, respectively.

For the period ended October 31, 2020, the fund incurred net realized gains of $13,227,780 from redemptions in kind. A redemption in kind occurs when a fund delivers securities from its portfolio in lieu of cash as payment to a redeeming shareholder.

19



5. Capital Share Transactions

Transactions in shares of the fund were as follows:
Year ended
October 31, 2020
Year ended
October 31, 2019(1)
Shares Amount Shares Amount
Investor Class/Shares Authorized 3,000,000,000  3,000,000,000 
Sold 10,005,335  $ 565,084,480  7,271,579  $ 338,362,927 
Issued in reinvestment of distributions 9,306,297  478,901,904  17,133,838  704,543,764 
Redeemed (23,598,620) (1,325,972,063) (19,883,790) (933,688,053)
(4,286,988) (281,985,679) 4,521,627  109,218,638 
I Class/Shares Authorized 120,000,000  120,000,000 
Sold 3,516,331  210,134,766  3,624,881  178,398,381 
Issued in reinvestment of distributions 257,034  13,774,479  611,707  26,101,541 
Redeemed (2,262,344) (130,239,567) (5,408,439) (271,836,094)
1,511,021  93,669,678  (1,171,851) (67,336,172)
Y Class/Shares Authorized 30,000,000  30,000,000 
Sold 7,598  435,257  5,158  249,374 
Issued in reinvestment of distributions 534  28,722  918  39,247 
Redeemed (7,612) (457,476) (1,132) (51,484)
520  6,503  4,944  237,137 
A Class/Shares Authorized 60,000,000  60,000,000 
Sold 873,790  47,417,147  639,406  28,146,102 
Issued in reinvestment of distributions 103,252  5,038,693  182,881  7,165,291 
Redeemed (747,854) (39,456,212) (632,688) (28,166,501)
229,188  12,999,628  189,599  7,144,892 
C Class/Shares Authorized 30,000,000  30,000,000 
Sold 194,165  8,625,235  211,178  7,569,450 
Issued in reinvestment of distributions 20,036  802,646  26,806  877,102 
Redeemed (160,091) (7,166,955) (93,382) (3,442,472)
54,110  2,260,926  144,602  5,004,080 
R Class/Shares Authorized 30,000,000  30,000,000 
Sold 246,296  13,528,987  197,063  8,482,452 
Issued in reinvestment of distributions 17,503  826,153  34,308  1,305,420 
Redeemed (195,157) (10,614,721) (199,457) (8,334,487)
68,642  3,740,419  31,914  1,453,385 
R5 Class/Shares Authorized 30,000,000  30,000,000 
Sold 1,897  120,588  2,002  94,159 
Issued in reinvestment of distributions 45  2,404  10  448 
Redeemed (28) (1,589) (339) (16,599)
1,914  121,403  1,673  78,008 
R6 Class/Shares Authorized 110,000,000  110,000,000 
Sold 2,682,757  161,316,501  2,436,356  117,344,335 
Issued in reinvestment of distributions 304,162  16,339,604  587,616  25,097,065 
Redeemed (4,473,539) (248,503,847) (1,676,518) (82,067,166)
(1,486,620) (70,847,742) 1,347,454  60,374,234 
G Class/Shares Authorized 80,000,000  80,000,000 
Sold 98 5,000
Issued in reinvestment of distributions 217  —  — 
217  98  5,000 
Net increase (decrease) (3,908,209) $ (240,034,647) 5,070,060  $ 116,179,202 

(1)August 1, 2019 (commencement of sale) through October 31, 2019 for the G Class.
20



6. Fair Value Measurements

The fund’s investments valuation process is based on several considerations and may use multiple inputs to determine the fair value of the investments held by the fund. In conformity with accounting principles generally accepted in the United States of America, the inputs used to determine a valuation are classified into three broad levels.

Level 1 valuation inputs consist of unadjusted quoted prices in an active market for identical investments.

Level 2 valuation inputs consist of direct or indirect observable market data (including quoted prices for comparable investments, evaluations of subsequent market events, interest rates, prepayment speeds, credit risk, etc.). These inputs also consist of quoted prices for identical investments initially expressed in local currencies that are adjusted through translation into U.S. dollars.

Level 3 valuation inputs consist of unobservable data (including a fund’s own assumptions).

The level classification is based on the lowest level input that is significant to the fair valuation measurement. The valuation inputs are not necessarily an indication of the risks associated with investing in these securities or other financial instruments.
The following is a summary of the level classifications as of period end. The Schedule of Investments provides additional information on the fund’s portfolio holdings.
Level 1 Level 2 Level 3
Assets
Investment Securities
Common Stocks $ 15,596,286,314  $ 370,738,511  — 
Temporary Cash Investments —  3,260,472  — 
$ 15,596,286,314  $ 373,998,983  — 
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 470,883  — 
      
Liabilities
Other Financial Instruments
Forward Foreign Currency Exchange Contracts —  $ 250,971  — 

7. Derivative Instruments

Foreign Currency Risk — The fund is subject to foreign currency exchange rate risk in the normal course of pursuing its investment objectives. The value of foreign investments held by a fund may be significantly affected by changes in foreign currency exchange rates. The dollar value of a foreign security generally decreases when the value of the dollar rises against the foreign currency in which the security is denominated and tends to increase when the value of the dollar declines against such foreign currency. A fund may enter into forward foreign currency exchange contracts to reduce a fund's exposure to foreign currency exchange rate fluctuations. The net U.S. dollar value of foreign currency underlying all contractual commitments held by a fund and the resulting unrealized appreciation or depreciation are determined daily. Realized gain or loss is recorded upon settlement of the contract. Net realized and unrealized gains or losses occurring during the holding period of forward foreign currency exchange contracts are a component of net realized gain (loss) on forward foreign currency exchange contract transactions and change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts, respectively. A fund bears the risk of an unfavorable change in the foreign currency exchange rate underlying the forward contract. Additionally, losses, up to the fair value, may arise if the counterparties do not perform under the contract terms. The fund's average U.S. dollar exposure to foreign currency risk derivative instruments held during the period was $76,100,205.

21



The value of foreign currency risk derivative instruments as of October 31, 2020, is disclosed on the Statement of Assets and Liabilities as an asset of $470,883 in unrealized appreciation on forward foreign currency exchange contracts and a liability of $250,971 in unrealized depreciation on forward foreign currency exchange contracts. For the year ended October 31, 2020, the effect of foreign currency risk derivative instruments on the Statement of Operations was $(2,337,508) in net realized gain (loss) on forward foreign currency exchange contract transactions and $180,160 in change in net unrealized appreciation (depreciation) on forward foreign currency exchange contracts.

8. Risk Factors

The value of the fund’s shares will go up and down, sometimes rapidly or unpredictably, based on the performance of the securities owned by the fund and other factors generally affecting the securities market. Market risks, including political, regulatory, economic and social developments, can affect the value of the fund’s investments. Natural disasters, public health emergencies, terrorism and other unforeseeable events may lead to increased market volatility and may have adverse long-term effects on world economies and markets generally.

9. Federal Tax Information

On December 8, 2020, the fund declared and paid a per-share distribution from net realized gains to shareholders of record on December 7, 2020 of $2.1247 for the Investor Class, I Class, Y Class, A Class, C Class, R Class, R5 Class, R6 Class and G Class.

The tax character of distributions paid during the years ended October 31, 2020 and October 31, 2019 were as follows:
2020 2019
Distributions Paid From
Ordinary income —  $ 1,545,620 
Long-term capital gains $ 537,382,637  $ 792,085,561 

The book-basis character of distributions made during the year from net investment income or net realized gains may differ from their ultimate characterization for federal income tax purposes. These differences reflect the differing character of certain income items and net realized gains and losses for financial statement and tax purposes, and may result in reclassification among certain capital accounts on the financial statements.

As of period end, the federal tax cost of investments and the components of distributable earnings on a tax-basis were as follows:

Federal tax cost of investments $ 4,471,976,122 
Gross tax appreciation of investments $ 11,564,877,638 
Gross tax depreciation of investments (66,568,463)
Net tax appreciation (depreciation) of investments 11,498,309,175 
Net tax appreciation (depreciation) on derivatives and translation of assets and liabilities in foreign currencies 1,358 
Net tax appreciation (depreciation) $ 11,498,310,533 
Undistributed ordinary income — 
Accumulated long-term gains $ 508,947,551 
Late-year ordinary loss deferral $ (49,770,668)

The difference between book-basis and tax-basis unrealized appreciation (depreciation) is attributable primarily to the tax deferral of losses on wash sales.

Loss deferrals represent certain qualified losses that the fund has elected to treat as having been incurred in the following fiscal year for federal income tax purposes.

22



Financial Highlights
For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
Investor Class
2020 $50.27 (0.21) 18.55 18.34 (2.23) (2.23) $66.38 37.77% 0.97% (0.36)% 6% $14,648,925 
2019 $47.74 (0.06) 5.92 5.86 (3.33) (3.33) $50.27 13.83% 0.97% (0.13)% 13% $11,308,500 
2018 $44.59 (0.06) 5.82 5.76 (0.07) (2.54) (2.61) $47.74 13.44% 0.97% (0.12)% 17% $10,524,969 
2017 $35.83 0.07 10.39 10.46 (0.10) (1.60) (1.70) $44.59 30.42% 0.98% 0.17% 16% $9,593,102 
2016 $37.81 0.06 (0.14) (0.08) (0.08) (1.82) (1.90) $35.83 (0.06)% 0.98% 0.19% 18% $7,790,085 
I Class
2020 $52.25 (0.10) 19.33 19.23 (2.23) (2.23) $69.25 38.05% 0.77% (0.16)% 6% $588,451 
2019 $49.39 0.03 6.16 6.19 (3.33) (3.33) $52.25 14.05% 0.77% 0.07% 13% $365,036 
2018 $46.04 0.03 6.02 6.05 (0.16) (2.54) (2.70) $49.39 13.68% 0.77% 0.08% 17% $402,938 
2017 $36.95 0.14 10.73 10.87 (0.18) (1.60) (1.78) $46.04 30.66% 0.78% 0.37% 16% $322,059 
2016 $38.93 0.14 (0.14) (0.16) (1.82) (1.98) $36.95 0.14% 0.78% 0.39% 18% $198,930 
Y Class
2020 $52.42 (0.01) 19.41 19.40 (2.23) (2.23) $69.59 38.26% 0.62% (0.01)% 6% $1,708 
2019 $49.47 0.10 6.18 6.28 (3.33) (3.33) $52.42 14.22% 0.62% 0.22% 13% $1,259 
2018 $46.07 0.11 6.02 6.13 (0.19) (2.54) (2.73) $49.47 13.85% 0.62% 0.23% 17% $944 
2017(3)
$39.40 0.10 6.57 6.67 $46.07 16.93%
0.63%(4)
0.43%(4)
16%(5)
$6 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
A Class
2020 $47.79 (0.34) 17.59 17.25 (2.23) (2.23) $62.81 37.43% 1.22% (0.61)% 6% $167,682 
2019 $45.67 (0.17) 5.62 5.45 (3.33) (3.33) $47.79 13.54% 1.22% (0.38)% 13% $116,630 
2018 $42.80 (0.17) 5.58 5.41 (2.54) (2.54) $45.67 13.15% 1.22% (0.37)% 17% $102,806 
2017 $34.45 (0.04) 10.00 9.96 (0.01) (1.60) (1.61) $42.80 30.10% 1.23% (0.08)% 16% $83,130 
2016 $36.43 (0.02) (0.14) (0.16) (1.82) (1.82) $34.45 (0.31)% 1.23% (0.06)% 18% $58,829 
C Class
2020 $39.65 (0.62) 14.43 13.81 (2.23) (2.23) $51.23 36.39% 1.97% (1.36)% 6% $24,320 
2019 $38.77 (0.43) 4.64 4.21 (3.33) (3.33) $39.65 12.69% 1.97% (1.13)% 13% $16,676 
2018 $36.96 (0.45) 4.80 4.35 (2.54) (2.54) $38.77 12.32% 1.97% (1.12)% 17% $10,700 
2017 $30.17 (0.28) 8.67 8.39 (1.60) (1.60) $36.96 29.12% 1.98% (0.83)% 16% $5,359 
2016 $32.36 (0.25) (0.12) (0.37) (1.82) (1.82) $30.17 (1.03)% 1.98% (0.81)% 18% $3,306 
R Class
2020 $46.31 (0.46) 17.00 16.54 (2.23) (2.23) $60.62 37.08% 1.47% (0.86)% 6% $26,729 
2019 $44.47 (0.28) 5.45 5.17 (3.33) (3.33) $46.31 13.26% 1.47% (0.63)% 13% $17,240 
2018 $41.84 (0.28) 5.45 5.17 (2.54) (2.54) $44.47 12.87% 1.47% (0.62)% 17% $15,137 
2017 $33.79 (0.12) 9.77 9.65 (1.60) (1.60) $41.84 29.75% 1.48% (0.33)% 16% $11,345 
2016 $35.85 (0.10) (0.14) (0.24) (1.82) (1.82) $33.79 (0.55)% 1.48% (0.31)% 18% $9,066 




For a Share Outstanding Throughout the Years Ended October 31 (except as noted)
Per-Share Data Ratios and Supplemental Data
Income From Investment Operations: Distributions From: Ratio to Average Net Assets of:
Net Asset
Value,
Beginning
of Period
Net
Investment
Income
(Loss)
(1)
Net
Realized
and
Unrealized
Gain (Loss)
Total From
Investment
Operations
 Net
Investment
Income
Net
Realized
Gains
Total
Distributions
Net Asset
Value,
End
of Period
Total
Return
(2)
Operating
Expenses
Net
Investment
Income
(Loss)
Portfolio
Turnover
Rate
Net
Assets,
End of
Period
(in thousands)
R5 Class
2020 $52.28 (0.12) 19.36 19.24 (2.23) (2.23) $69.29 38.05% 0.77% (0.16)% 6% $258 
2019 $49.42 0.01 6.18 6.19 (3.33) (3.33) $52.28 14.04% 0.77% 0.07% 13% $94 
2018 $46.04 0.04 6.02 6.06 (0.14) (2.54) (2.68) $49.42 13.69% 0.77% 0.08% 17% $7 
2017(3)
$39.41 0.07 6.56 6.63 $46.04 16.82%
0.78%(4)
0.28%(4)
16%(5)
$6 
R6 Class
2020 $52.36
(6)
19.38 19.38 (2.23) (2.23) $69.51 38.26% 0.62% (0.01)% 6% $509,484 
2019 $49.42 0.10 6.17 6.27 (3.33) (3.33) $52.36 14.22% 0.62% 0.22% 13% $461,623 
2018 $46.07 0.10 6.02 6.12 (0.23) (2.54) (2.77) $49.42 13.85% 0.62% 0.23% 17% $369,109 
2017 $36.97 0.18 10.75 10.93 (0.23) (1.60) (1.83) $46.07 30.86% 0.63% 0.52% 16% $233,309 
2016 $38.95 0.17 (0.12) 0.05 (0.21) (1.82) (2.03) $36.97 0.29% 0.63% 0.54% 18% $83,367 
G Class
2020 $52.44 0.37 19.46 19.83 (2.23) (2.23) $70.04 39.09%
0.01%(7)
0.60%(7)
6% $7 
2019(8)
$51.28 0.10 1.06 1.16 $52.44 2.26%
0.00%(4)(9)(10)
0.78%(4)(10)
13%(11)
$5 





Notes to Financial Highlights
(1)Computed using average shares outstanding throughout the period.
(2)Total returns are calculated based on the net asset value of the last business day and do not reflect applicable sales charges, if any. Total returns for periods less than one year are not annualized.
(3)April 10, 2017 (commencement of sale) through October 31, 2017.
(4)Annualized.
(5)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2017.
(6)Per-share amount was less than $0.005.
(7)The ratio of operating expenses to average net assets before expense waiver and the ratio of net investment income (loss) to average net assets before expense waiver was 0.62% and (0.01)%, respectively.
(8)August 1, 2019 (commencement of sale) through October 31, 2019.
(9)Ratio was less than 0.005%.
(10)The annualized ratio of operating expenses to average net assets before expense waiver and the annualized ratio of net investment income (loss) to average net assets before expense waiver was 0.62% and 0.16%, respectively.
(11)Portfolio turnover is calculated at the fund level. Percentage indicated was calculated for the year ended October 31, 2019.


See Notes to Financial Statements.




Report of Independent Registered Public Accounting Firm

To the Shareholders and the Board of Directors of American Century Mutual Funds, Inc.:

Opinion on the Financial Statements and Financial Highlights

We have audited the accompanying statement of assets and liabilities, including the schedule of investments, of Ultra® Fund (the “Fund”), one of the funds constituting the American Century Mutual Funds, Inc., as of October 31, 2020, the related statement of operations for the year then ended, the statements of changes in net assets for each of the two years in the period then ended, the financial highlights for each of the five years in the period then ended, and the related notes. In our opinion, the financial statements and financial highlights present fairly, in all material respects, the financial position of Ultra® Fund of the American Century Mutual Funds, Inc. as of October 31, 2020, and the results of its operations for the year then ended, the changes in its net assets for each of the two years in the period then ended, and the financial highlights for each of the five years in the period then ended, in conformity with accounting principles generally accepted in the United States of America.

Basis for Opinion

These financial statements and financial highlights are the responsibility of the Fund's management. Our responsibility is to express an opinion on the Fund’s financial statements and financial highlights based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Fund in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements and financial highlights are free of material misstatement, whether due to error or fraud. The Fund is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Fund’s internal control over financial reporting. Accordingly, we express no such opinion.

Our audits included performing procedures to assess the risks of material misstatement of the financial statements and financial highlights, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements and financial highlights. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements and financial highlights. Our procedures included confirmation of securities owned as of October 31, 2020, by correspondence with the custodian and brokers; when replies were not received from brokers, we performed other auditing procedures. We believe that our audits provide a reasonable basis for our opinion.

DELOITTE & TOUCHE LLP

Kansas City, Missouri
December 16, 2020

We have served as the auditor of one or more American Century investment companies since 1997.
27



Management

The Board of Directors

The individuals listed below serve as directors of the funds. Each director will continue to serve in this capacity until death, retirement, resignation or removal from office. The board has adopted a mandatory retirement age for directors who are not “interested persons,” as that term is defined in the Investment Company Act (independent directors). Independent directors shall retire by December 31 of the year in which they reach their 75th birthday.
Mr. Thomas is an “interested person” because he currently serves as President and Chief Executive Officer of American Century Companies, Inc. (ACC), the parent company of American Century Investment Management, Inc. (ACIM or the advisor). The other directors (more than three-fourths of the total number) are independent. They are not employees, directors or officers of, and have no financial interest in, ACC or any of its wholly owned, direct or indirect, subsidiaries, including ACIM, American Century Investment Services, Inc. (ACIS) and American Century Services, LLC (ACS), and they do not have any other affiliations, positions or relationships that would cause them to be considered “interested persons” under the Investment Company Act. The directors serve in this capacity for seven (in the case of Jonathan S. Thomas, 16; and Stephen E. Yates, 8) registered investment companies in the American Century Investments family of funds.
The following table presents additional information about the directors. The mailing address for each director is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Thomas W. Bunn (1953) Director Since 2017 Retired 62 SquareTwo Financial; Barings (formerly Babson Capital Funds Trust) (2013 to 2016)
Chris H. Cheesman
(1962)
Director Since 2019
Retired. Senior Vice President & Chief Audit Executive, AllianceBernstein (1999 to 2018)
62 None
Barry Fink
(1955)
Director Since 2012 (independent since 2016) Retired 62 None
Rajesh K. Gupta
(1960)
Director Since 2019
Partner Emeritus, SeaCrest Investment Management and SeaCrest Wealth Management (2019 to Present); Chief Executive Officer and Chief Investment Officer, SeaCrest Investment Management (2006 to 2019); Chief Executive Officer and Chief Investment Officer, SeaCrest Wealth Management (2008 to 2019)
62 None
28



Name
(Year of Birth)
Position(s) Held with Funds Length of Time Served Principal Occupation(s) During Past 5 Years Number of American Century Portfolios Overseen by Director Other Directorships Held During Past 5 Years
Independent Directors
Lynn Jenkins
(1963)
Director Since 2019
Consultant, LJ Strategies (2019 to present); United States Representative, U.S. House of Representatives (2009 to 2018) 62 MGP Ingredients, Inc.
Jan M. Lewis
(1957)
Director Since 2011 Retired 62 None
John R. Whitten
(1946)
Director Since 2008 Retired 62 Onto Innovation Inc.; Rudolph Technologies, Inc. (2006 to 2019)
Stephen E. Yates
(1948)
Director and Chairman of the Board Since 2012 (Chairman since 2018) Retired 87 None
Interested Director
Jonathan S. Thomas
(1963)
Director Since 2007 President and Chief Executive Officer, ACC (2007 to present). Also serves as Chief Executive Officer, ACS; Executive Vice President, ACIM; Director, ACC, ACIM and other ACC subsidiaries 125 None
The Statement of Additional Information has additional information about the fund's directors and is available without charge, upon request, by calling 1-800-345-2021.
29



Officers

The following table presents certain information about the executive officers of the funds. Each officer serves as an officer for each of the 16 (in the case of Robert J. Leach, 15) investment companies in the American Century family of funds. No officer is compensated for his or her service as an officer of the funds. The listed officers are interested persons of the funds and are appointed or re-appointed on an annual basis. The mailing address for each officer listed below is 4500 Main Street, Kansas City, Missouri 64111.
Name
(Year of Birth)
Offices with the Funds Principal Occupation(s) During the Past Five Years
Patrick Bannigan
(1965)
President since 2019 Executive Vice President and Director, ACC (2012 to present); Chief Financial Officer, Chief Accounting Officer and Treasurer, ACC (2015 to present). Also serves as President, ACS; Vice President, ACIM; Chief Financial Officer, Chief Accounting Officer and/or Director, ACIM, ACS and other ACC subsidiaries
R. Wes Campbell
(1974)
Chief Financial Officer and Treasurer since 2018 Vice President, ACS, (2020 to present); Investment Operations and Investment Accounting, ACS (2000 to present)
Amy D. Shelton
(1964)
Chief Compliance Officer and Vice President since 2014 Chief Compliance Officer, American Century funds, (2014 to present); Chief Compliance Officer, ACIM (2014 to present); Chief Compliance Officer, ACIS (2009 to present). Also serves as Vice President, ACIS
Charles A. Etherington
(1957)
General Counsel since 2007 and Senior Vice President since 2006 Attorney, ACC (1994 to present); Vice President, ACC (2005 to present); General Counsel, ACC (2007 to present). Also serves as General Counsel, ACIM, ACS, ACIS and other ACC subsidiaries; and Senior Vice President, ACIM and ACS
C. Jean Wade
(1964)
Vice President since 2012 Senior Vice President, ACS (2017 to present); Vice President, ACS (2000 to 2017)
Robert J. Leach
(1966)
Vice President since 2006 Vice President, ACS (2000 to present)
David H. Reinmiller
(1963)
Vice President since 2000 Attorney, ACC (1994 to present). Also serves as Vice President, ACIM and ACS
Ward D. Stauffer
(1960)
Secretary since 2005 Attorney, ACC (2003 to present)





30



Approval of Management Agreement

At a meeting held on June 24, 2020, the Fund’s Board of Directors (the "Board") unanimously approved the renewal of the management agreement pursuant to which American Century Investment Management, Inc. (the “Advisor”) acts as the investment advisor for the Fund. Under Section 15(c) of the Investment Company Act, contracts for investment advisory services are required to be reviewed, evaluated, and approved by a majority of a fund’s directors (the “Directors”), including a majority of the independent Directors, each year.

Prior to its consideration of the renewal of the management agreement, the Directors requested and reviewed extensive data and information compiled by the Advisor and certain independent providers of evaluation data concerning the Fund and the services provided to the Fund by the Advisor. This review was in addition to the oversight and evaluation undertaken by the Board and its committees on a continual basis and the information received was supplemental to the extensive information that the Board and its committees receive and consider throughout the year.

In connection with its consideration of the renewal of the management agreement, the Board’s review and evaluation of the services provided by the Advisor included, but was not limited to, the following:

the nature, extent, and quality of investment management, shareholder services, and other services provided and to be provided to the Fund;
the wide range of other programs and services provided and to be provided to the Fund and its shareholders on a routine and non-routine basis;
the Fund’s investment performance, including data comparing the Fund's performance to appropriate benchmarks and/or a peer group of other mutual funds with similar investment objectives and strategies;
the cost of owning the Fund compared to the cost of owning similar funds;
the compliance policies, procedures, and regulatory experience of the Advisor and the Fund's service providers;
the Advisor’s strategic plans;
the Advisor’s business continuity plans and specifically its response to the COVID-19 pandemic;
financial data showing the cost of services provided to the Fund, the profitability of the Fund to the Advisor, and the overall profitability of the Advisor;
possible economies of scale associated with the Advisor’s management of the Fund and other accounts;
services provided and charges to the Advisor's other investment management clients;
acquired fund fees and expenses;
payments and practices in connection with financial intermediaries holding shares of the Fund and the services provided by intermediaries in connection therewith; and
possible collateral benefits to the Advisor from the management of the Fund.

The Board held two meetings to consider the renewal. The independent Directors also met in private session three times to review and discuss the information provided in response to their request. The independent Directors held active discussions with the Advisor regarding the renewal of the management agreement, requesting supplemental information, and reviewing information provided by the Advisor in response thereto. The independent Directors had the benefit of the advice of their independent counsel throughout the process.

Factors Considered

The Directors considered all of the information provided by the Advisor, the independent data providers, and independent counsel in connection with the approval. They determined that the information was sufficient for them to evaluate the management agreement for the Fund. In connection with their review, the Directors did not identify any single factor as being all-important or
31



controlling, and each Director may have attributed different levels of importance to different factors. In deciding to renew the management agreement, the Board based its decision on a number of factors, including without limitation the following:

Nature, Extent and Quality of Services — Generally. Under the management agreement, the Advisor is responsible for providing or arranging for all services necessary for the operation of the Fund. The Board noted that the Advisor provides or arranges at its own expense a wide variety of services including without limitation the following:

constructing and designing the Fund
portfolio research and security selection
initial capitalization/funding
securities trading
Fund administration
custody of Fund assets
daily valuation of the Fund’s portfolio
shareholder servicing and transfer agency, including shareholder confirmations, recordkeeping, and communications
legal services (except the independent Directors’ counsel)
regulatory and portfolio compliance
financial reporting
marketing and distribution (except amounts paid by the Fund under Rule 12b-1 plans)

The Board noted that many of these services have expanded over time in terms of both quantity and complexity in response to shareholder demands, competition in the industry, changing distribution channels, and the changing regulatory environment.

Investment Management Services. The nature of the investment management services provided to the Fund is quite complex and allows Fund shareholders access to professional money management, instant diversification of their investments within an asset class, the opportunity to easily diversify among asset classes by investing in or exchanging among various American Century Investments funds, and liquidity. In evaluating investment performance, the Board expects the Advisor to manage the Fund in accordance with its investment objectives and approved strategies. Further, the Directors recognize that the Advisor has an obligation to monitor trading activities, and in particular to seek the best execution of fund trades, and to evaluate the use of and payment for research. In providing these services, the Advisor utilizes teams of investment professionals (portfolio managers, analysts, research assistants, and securities traders) who require extensive information technology, research, training, compliance, and other systems to conduct their business. The Board, directly and through its Fund Performance Review Committee, provides oversight of the investment performance process. It regularly reviews investment performance information for the Fund, together with comparative information for appropriate benchmarks and/or peer groups of similarly-managed funds, over different time horizons. The Directors also review investment performance information during the management agreement renewal process. If performance concerns are identified, the Fund receives special reviews until performance improves, during which the Board discusses with the Advisor the reasons for such results (e.g., market conditions, security selection) and any efforts being undertaken to improve performance. The Fund’s performance was above its benchmark for the three-, five-, and ten-year periods and below its benchmark for the one-year period reviewed by the Board. The Board found the investment management services provided by the Advisor to the Fund to be satisfactory and consistent with the management agreement.

Shareholder and Other Services. Under the management agreement, the Advisor provides the Fund with a comprehensive package of transfer agency, shareholder, and other services. The Board, directly and through its various committees, regularly reviews reports and evaluations of such services at its regular meetings. These reports include, but are not limited to, information regarding the operational efficiency and accuracy of the shareholder and transfer agency services provided, staffing levels, shareholder satisfaction, technology support (including cyber security), new products and services offered to Fund shareholders, securities trading activities, portfolio
32



valuation services, auditing services, and legal and operational compliance activities. The Board found the services provided by the Advisor to the Fund under the management agreement to be competitive and of high quality.

COVID-19 Response. During 2020, much of the world experienced unprecedented change and challenges from the impacts of the rapidly evolving, worldwide spread of the COVID-19 virus. The Board evaluated the Advisor’s response to the COVID-19 pandemic and its impact on service to the Fund. The Board found that Fund shareholders have continued to receive the Advisor’s investment management and other services without disruption, and Advisor personnel have demonstrated great resiliency in providing those services. The Board, directly and through its Audit Committee, continues to monitor the impact of the pandemic and the response of each of the Fund’s service providers.

Costs of Services and Profitability. The Advisor provides detailed information concerning its cost of providing various services to the Fund, its profitability in managing the Fund (pre- and post-distribution), its overall profitability, and its financial condition. The Directors have reviewed with the Advisor the methodology used to prepare this financial information. This information is considered in evaluating the Advisor’s financial condition, its ability to continue to provide services under the management agreement, and the reasonableness of the current management fee. The Board concluded that the Advisor’s profits were reasonable in light of the services provided to the Fund.

Ethics. The Board generally considers the Advisor’s commitment to providing quality services to shareholders and to conducting its business ethically. They noted that the Advisor’s practices generally meet or exceed industry best practices.

Economies of Scale. The Board also reviewed information provided by the Advisor regarding the possible existence of economies of scale in connection with the management of the Fund. The Board concluded that economies of scale are difficult to measure and predict with precision, especially on a fund-by-fund basis. The Board concluded that the Advisor is appropriately sharing economies of scale, to the extent they exist, through its competitive fee structure, offering competitive fees from fund inception, and through reinvestment in its business, infrastructure, investment capabilities and initiatives to provide shareholders additional content and services. The Board also noted that economies of scale are shared with the Fund and its shareholders through management fee breakpoints that serve to reduce the effective management fee as the assets of the Fund grow.

Comparison to Other Funds’ Fees. The management agreement provides that the Fund pays the Advisor a single, all-inclusive (or unified) management fee for providing all services necessary for the management and operation of the Fund, other than brokerage expenses, expenses attributable to short sales, taxes, interest, extraordinary expenses, fees and expenses of the Fund’s independent Directors (including their independent legal counsel), and expenses incurred in connection with the provision of shareholder services and distribution services under a plan adopted pursuant to Rule 12b-1 under the Investment Company Act. Under the unified fee structure, the Advisor is responsible for providing all investment advisory, custody, audit, administrative, compliance, recordkeeping, marketing and shareholder services, or arranging and supervising third parties to provide such services. By contrast, most other funds are charged a variety of fees, including an investment advisory fee, a transfer agency fee, an administrative fee, distribution charges, and other expenses. Other than their investment advisory fees and any applicable Rule 12b-1 distribution fees, all other components of the total fees charged by these other funds may be increased without shareholder approval. The Board believes the unified fee structure is a benefit to Fund shareholders because it clearly discloses to shareholders the cost of owning Fund shares, and, since the unified fee cannot be increased without a vote of Fund shareholders, it shifts to the Advisor the risk of increased costs of operating the Fund and provides a direct incentive to minimize administrative inefficiencies. Part of the Board’s analysis of fee levels involves reviewing certain evaluative data compiled by an independent provider comparing the Fund’s unified fee to the total expense ratios of its peers. The unified fee charged to shareholders of the Fund was above the median of the total expense ratios of the Fund’s peer expense universe
33



and was within the range of its peer expense group. The Board concluded that the management fee paid by the Fund to the Advisor under the management agreement is reasonable in light of the services provided to the Fund.

Comparison to Fees and Services Provided to Other Clients of the Advisor. The Board also requested and received information from the Advisor concerning the nature of the services, fees, costs, and profitability of its advisory services to advisory clients other than the Fund. They observed that these varying types of client accounts require different services and involve different regulatory and entrepreneurial risks than the management of the Fund. The Board analyzed this information and concluded that the fees charged and services provided to the Fund were reasonable by comparison.

Payments to Intermediaries. The Directors also requested and received a description of payments made to intermediaries by the Fund and the Advisor and services provided in response thereto. These payments include various payments made by the Fund or the Advisor to different types of intermediaries and recordkeepers for distribution and service activities provided for the Fund. The Directors reviewed such information and received representations from the Advisor that all such payments by the Fund were made pursuant to the Fund's Rule 12b-1 Plan and that all such payments by the Advisor were made from the Advisor’s resources and reasonable profits. The Board found such payments to be reasonable in scope and purpose.

Collateral or “Fall-Out” Benefits Derived by the Advisor. The Board considered the possible existence of collateral benefits the Advisor may receive as a result of its relationship with the Fund. They concluded that the Advisor’s primary business is managing mutual funds and it generally does not use fund or shareholder information to generate profits in other lines of business, and therefore does not derive any significant collateral benefits from them. To the extent there are potential collateral benefits, the board has been advised and has taken this into consideration in its review of the management contract with the Fund. The Board noted that additional assets from other clients may offer the Advisor some benefit from increased leverage with service providers and counterparties. Additionally, the Advisor may receive proprietary research from broker-dealers that execute fund portfolio transactions, which the Board concluded is likely to benefit other clients of the Advisor, as well as Fund shareholders. The Board also determined that the Advisor is able to provide investment management services to certain clients other than the Fund, at least in part, due to its existing infrastructure built to serve the fund complex. The Board concluded that appropriate allocation methodologies had been employed to assign resources and the cost of those resources to these other clients and, where expressly provided, these other client assets may be included with the assets of the Fund to determine breakpoints in the management fee schedule.

Existing Relationship. The Board also considered whether there was any reason for not continuing the existing arrangement with the Advisor. In this regard, the Board was mindful of the potential disruptions of the Fund’s operations and various risks, uncertainties, and other effects that could occur as a result of a decision not to continue such relationship. In particular, the Board recognized that most shareholders have invested in the Fund on the strength of the Advisor’s industry standing and reputation and in the expectation that the Advisor will have a continuing role in providing advisory services to the Fund.

Conclusion of the Directors. As a result of this process, the Board, including all of the independent Directors, taking into account all of the factors discussed above and the information provided by the Advisor and others in connection with its review and throughout the year, determined that the management fee is fair and reasonable in light of the services provided and that the investment management agreement between the Fund and the Advisor should be renewed.
34



Additional Information

Retirement Account Information

As required by law, distributions you receive from certain retirement accounts are subject to federal income tax withholding, unless you elect not to have withholding apply*. Tax will be withheld on the total amount withdrawn even though you may be receiving amounts that are not subject to withholding, such as nondeductible contributions. In such case, excess amounts of withholding could occur. You may adjust your withholding election so that a greater or lesser amount will be withheld.
If you don’t want us to withhold on this amount, you must notify us to not withhold the federal income tax. You may notify us in writing or in certain situations by telephone or through other electronic means. For systematic withdrawals, your withholding election will remain in effect until revoked or changed by filing a new election. You have the right to revoke your election at any time and change your withholding percentage for future distributions.
Remember, even if you elect not to have income tax withheld, you are liable for paying income tax on the taxable portion of your withdrawal. If you elect not to have income tax withheld or you don’t have enough income tax withheld, you may be responsible for payment of estimated tax. You may incur penalties under the estimated tax rules if your withholding and estimated tax payments are not sufficient. You can reduce or defer the income tax on a distribution by directly or indirectly rolling such distribution over to another IRA or eligible plan. You should consult your tax advisor for additional information.
State tax will be withheld if, at the time of your distribution, your address is within one of the mandatory withholding states and you have federal income tax withheld (or as otherwise required by state law). State taxes will be withheld from your distribution in accordance with the respective state rules.
*Some 403(b), 457 and qualified retirement plan distributions may be subject to 20% mandatory withholding, as they are subject to special tax and withholding rules.  Your plan administrator or plan sponsor is required to provide you with a special tax notice explaining those rules at the time you request a distribution.  If applicable, federal and/or state taxes may be withheld from your distribution amount.


Proxy Voting Policies

A description of the policies that the fund's investment advisor uses in exercising the voting rights associated with the securities purchased and/or held by the fund is available without charge, upon request, by calling 1-800-345-2021. It is also available on American Century Investments’ website at americancentury.com/proxy and on the Securities and Exchange Commission’s website at sec.gov. Information regarding how the investment advisor voted proxies relating to portfolio securities during the most recent 12-month period ended June 30 is available on americancentury.com/proxy. It is also available at sec.gov.


Quarterly Portfolio Disclosure

The fund files its complete schedule of portfolio holdings with the Securities and Exchange Commission (SEC) for the first and third quarters of each fiscal year as an exhibit to its reports on Form N-PORT. The fund’s Form N-PORT reports are available on the SEC’s website at sec.gov. The fund also makes its complete schedule of portfolio holdings for the most recent quarter of its fiscal year available on its website at americancentury.com and, upon request, by calling 1-800-345-2021.




35



Other Tax Information

The following information is provided pursuant to provisions of the Internal Revenue Code.

The fund hereby designates $537,382,637, or up to the maximum amount allowable, as long-term capital gain distributions (20% rate gain distributions) for the fiscal year ended October 31, 2020.
36



Notes
37



Notes
38



Notes
39



Notes

40








IMAGE81.JPG
Contact Us americancentury.com
Automated Information Line 1-800-345-8765
Investor Services Representative 1-800-345-2021
or 816-531-5575
Investors Using Advisors 1-800-378-9878
Business, Not-For-Profit, Employer-Sponsored Retirement Plans 1-800-345-3533
Banks and Trust Companies, Broker-Dealers, Financial Professionals, Insurance Companies 1-800-345-6488
Telecommunications Relay Service for the Deaf 711
American Century Mutual Funds, Inc.
Investment Advisor:
American Century Investment Management, Inc.
Kansas City, Missouri
This report and the statements it contains are submitted for the general information of our shareholders. The report is not authorized for distribution to prospective investors unless preceded or accompanied by an effective prospectus.
©2020 American Century Proprietary Holdings, Inc. All rights reserved.
CL-ANN-90975 2012




ITEM 2. CODE OF ETHICS.

(a) The registrant has adopted a Code of Ethics for Senior Financial Officers that applies to the registrant’s principal executive officer, principal financial officer, principal accounting officer, and persons performing similar functions.

(b) No response required.

(c) None.

(d) None.

(e) Not applicable.

(f) The registrant’s Code of Ethics for Senior Financial Officers was filed as Exhibit 12 (a)(1) to American Century Asset Allocation Portfolios, Inc.’s Annual Certified Shareholder Report on Form N-CSR, File No. 811-21591, on September 29, 2005, and is incorporated herein by reference.


ITEM 3. AUDIT COMMITTEE FINANCIAL EXPERT.

(a)(1) The registrant’s board has determined that the registrant has at least one audit committee financial expert serving on its audit committee.

(a)(2) John R. Whitten, Thomas Bunn, Chris H. Cheesman and Lynn M. Jenkins are the registrant’s designated audit committee financial experts. They are “independent” as defined in Item 3 of Form N-CSR.

(a)(3) Not applicable.

(b) No response required.

(c) No response required.

(d) No response required.


ITEM 4. PRINCIPAL ACCOUNTANT FEES AND SERVICES.

(a) Audit Fees.

The aggregate fees billed for each of the last two fiscal years for professional services rendered by the principal accountant for the audit of the registrant’s annual financial statements or services that are normally provided by the accountant in connection with statutory and regulatory filings or engagements for those fiscal years were as follows:

FY 2019: $261,180
FY 2020: $199,255

(b) Audit-Related Fees.

The aggregate fees billed in each of the last two fiscal years for assurance and related services by the principal accountant that are reasonably related to the performance of the audit of the registrant’s financial statements and are not reported under paragraph (a) of this Item were as follows:





For services rendered to the registrant:

FY 2019: $0
FY 2020: $0

Fees required to be approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation S-X (relating to certain engagements for non-audit services with the registrant’s investment adviser and its affiliates):

FY 2019: $0
FY 2020: $0

(c) Tax Fees.

The aggregate fees billed in each of the last two fiscal years for professional services rendered by the principal accountant for tax compliance, tax advice, and tax planning were as follows:

For services rendered to the registrant:

FY 2019: $0
FY 2020: $0

Fees required to be approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation S-X (relating to certain engagements for non-audit services with the registrant’s investment adviser and its affiliates):

FY 2019: $0
FY 2020: $0

(d) All Other Fees.

The aggregate fees billed in each of the last two fiscal years for products and services provided by the principal accountant, other than the services reported in paragraphs (a) through (c) of this Item were as follows:

For services rendered to the registrant:

FY 2019: $0
FY 2020: $0

Fees required to be approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation S-X (relating to certain engagements for non-audit services with the registrant’s investment adviser and its affiliates):

FY 2019: $0
FY 2020: $0

(e)(1) In accordance with paragraph (c)(7)(i)(A) of Rule 2-01 of Regulation S-X, before the accountant is engaged by the registrant to render audit or non-audit services, the engagement is approved by the registrant’s audit committee. Pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation S-X, the registrant’s audit committee also pre-approves its accountant’s engagements for non-audit services with the registrant’s investment adviser, its parent company, and any entity controlled by, or under common control with the investment adviser that provides ongoing services to the registrant, if the engagement relates directly to the operations and financial reporting of the registrant.

(e)(2) All services described in each of paragraphs (b) through (d) of this Item were pre-approved before the engagement by the registrant’s audit committee pursuant to paragraph (c)(7)(i)(A) of Rule 2-01 of Regulation S-X. Consequently, none of such services were required to be approved by the audit committee pursuant to paragraph (c)(7)(i)(C).





(f) The percentage of hours expended on the principal accountant’s engagement to audit the registrant’s financial statements for the most recent fiscal year that were attributed to work performed by persons other than the principal accountant’s full-time, permanent employees was less than 50%.

(g) The aggregate non-audit fees billed by the registrant’s accountant for services rendered to the registrant, and rendered to the registrant’s investment adviser (not including any sub-adviser whose role is primarily portfolio management and is subcontracted with or overseen by another investment adviser), and any entity controlling, controlled by, or under common control with the adviser that provides ongoing services to the registrant for each of the last two fiscal years of the registrant were as follows:

FY 2019: $119,500
FY 2020: $0

(h) The registrant’s investment adviser and accountant have notified the registrant’s audit committee of all non-audit services that were rendered by the registrant’s accountant to the registrant’s investment adviser, its parent company, and any entity controlled by, or under common control with the investment adviser that provides services to the registrant, which services were not required to be pre-approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation S-X. The notification provided to the registrant’s audit committee included sufficient details regarding such services to allow the registrant’s audit committee to consider the continuing independence of its principal accountant.


ITEM 5. AUDIT COMMITTEE OF LISTED REGISTRANTS.

Not applicable.


ITEM 6. INVESTMENTS.

(a) The schedule of investments is included as part of the report to stockholders filed under Item 1 of this Form.

(b) Not applicable.

ITEM 7. DISCLOSURE OF PROXY VOTING POLICIES AND PROCEDURES FOR CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

Not applicable.


ITEM 8. PORTFOLIO MANAGERS OF CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

Not applicable.


ITEM 9. PURCHASES OF EQUITY SECURITIES BY CLOSED-END MANAGEMENT INVESTMENT COMPANY AND AFFILIATED PURCHASERS.

Not applicable.


ITEM 10. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.





During the reporting period, there were no material changes to the procedures by which shareholders may recommend nominees to the registrant’s board.


ITEM 11. CONTROLS AND PROCEDURES.

(a) The registrant's principal executive officer and principal financial officer have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940) are effective based on their evaluation of these controls and procedures as of a date within 90 days of the filing date of this report.

(b) There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the Investment Company Act of 1940) that occurred during the period covered by this report that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.


ITEM 12. DISCLOSURE OF SECURITIES LENDING ACTIVITIES FOR CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

Not applicable.


ITEM 13. EXHIBITS.

(a)(1) Registrant’s Code of Ethics for Senior Financial Officers, which is the subject of the disclosure required by Item 2 of Form N-CSR, was filed as Exhibit 12(a)(1) to American Century Asset Allocation Portfolios, Inc.’s Certified Shareholder Report on Form N-CSR, File No. 811-21591, on September 29, 2005.

(a)(2) Separate certifications by the registrant’s principal executive officer and principal financial officer, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 and Rule 30a-2(a) under the Investment Company Act of 1940, are filed and attached hereto as EX-99.CERT.

(a)(3) Not applicable.

(a)(4) Not applicable.

(b) A certification by the registrant’s chief executive officer and chief financial officer, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, is furnished and attached hereto as EX-99.906CERT.









SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Registrant: American Century Mutual Funds, Inc.
By: /s/ Patrick Bannigan
Name: Patrick Bannigan
Title: President
Date: December 30, 2020


Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.
By: /s/ Patrick Bannigan
Name: Patrick Bannigan
Title: President
(principal executive officer)
Date: December 30, 2020

By: /s/ R. Wes Campbell
Name: R. Wes Campbell
Title: Treasurer and
Chief Financial Officer
(principal financial officer)
Date: December 30, 2020



EX-99.CERT
CERTIFICATIONS

I, Patrick Bannigan, certify that:

1. I have reviewed this report on Form N-CSR of American Century Mutual Funds, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations, changes in net assets, and cash flows (if the financial statements are required to include a statement of cash flows) of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940) and internal control over financial reporting (as defined in Rule 30a-3(d) under the Investment Company Act of 1940) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of a date within 90 days prior to the filing date of this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the period covered by this report that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer and I have disclosed to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize, and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date: December 30, 2020
/s/ Patrick Bannigan
Patrick Bannigan
President
(principal executive officer)





I, R. Wes Campbell, certify that:

1. I have reviewed this report on Form N-CSR of American Century Mutual Funds, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations, changes in net assets, and cash flows (if the financial statements are required to include a statement of cash flows) of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940) and internal control over financial reporting (as defined in Rule 30a-3(d) under the Investment Company Act of 1940) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of a date within 90 days prior to the filing date of this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the period covered by this report that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer and I have disclosed to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize, and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date: December 30, 2020
/s/ R. Wes Campbell
R. Wes Campbell
Treasurer and Chief Financial Officer
(principal financial officer)



EX-99.906CERT

CERTIFICATION
PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


In connection with the shareholder report of American Century Mutual Funds, Inc. (the "Registrant") on Form N-CSR for the period ending October 31, 2020 (the "Report"), we, the undersigned, certify, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of Section 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Registrant.

Date: December 30, 2020
By: /s/ Patrick Bannigan
Patrick Bannigan
President
(chief executive officer)
By: /s/ R. Wes Campbell
R. Wes Campbell
Treasurer and Chief Financial Officer
(chief financial officer)