AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 1997

REGISTRATION NO. 333-


SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549


FORM S-3
REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933


ABIOMED, INC.
(EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
               DELAWARE                              04-2743260
    (STATE OR OTHER JURISDICTION OF    (I.R.S. EMPLOYERIDENTIFICATION NUMBER)
    INCORPORATION OR ORGANIZATION)


33 CHERRY HILL DRIVE
DANVERS, MASSACHUSETTS 01923
(978) 777-5410

(ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING
AREA CODE, OF REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)


DR. DAVID M. LEDERMAN
PRESIDENT AND CHIEF EXECUTIVE OFFICER
ABIOMED, INC.
33 CHERRY HILL DRIVE
DANVERS, MASSACHUSETTS 01923
(978) 777-5410

(NAME, ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER,
INCLUDING AREA CODE, OF AGENT FOR SERVICE)


COPIES TO:

   PHILIP J. FLINK, ESQUIRE               STEVEN C. BROWNE, ESQUIRE
BROWN, RUDNICK, FREED & GESMER         TESTA, HURWITZ & THIBEAULT, LLP
     ONE FINANCIAL CENTER                      125 HIGH STREET
  BOSTON, MASSACHUSETTS 02111            BOSTON, MASSACHUSETTS 02110
        (617) 856-8200                         (617) 248-7000

                            ---------------

APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: As soon as

practicable after the effective date of this Registration Statement.
If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, check the following box. [_]
If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. [_] If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. [_] If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. [_]
If delivery of the prospectus is expected to be made pursuant to Rule 434, check the following box. [_]

CALCULATION OF REGISTRATION FEE


                                                 PROPOSED       PROPOSED
                                  AMOUNT         MAXIMUM        MAXIMUM
  TITLE OF EACH CLASS OF          TO BE       OFFERING PRICE   AGGREGATE       AMOUNT OF
SECURITIES TO BE REGISTERED   REGISTERED(1)    PER SHARE(2)  OFFERING PRICE REGISTRATION FEE
--------------------------------------------------------------------------------------------
 Common Stock, $.01 par                          $17.125      $47,265,000      $14,322.73
  value.................     2,760,000 shares
--------------------------------------------------------------------------------------------
 Preferred Share Purchase
  Rights(3).............           --              --             --              --



(1) Includes up to 360,000 shares of Common Stock which may be purchased by the Underwriters to cover over-allotments, if any.
(2) Estimated solely for the purpose of determining the registration fee pursuant to Rule 457(c) under the Securities Act of 1933. Based upon the average of the high and low price of the Common Stock as reported on the Nasdaq National Market on September 24, 1997.
(3) Pursuant to a Rights Distribution made in August 1997, one right (each a "Right") is deemed to be delivered with each share of Common Stock issued by the Company. The Rights currently are not separately transferable apart from the Common Stock, nor are they exercisable until the occurrence of certain events. Accordingly, no independent value has been attributed to the Rights.

THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH
SECTION 8(A) OF THE SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME EFFECTIVE ON SUCH DATE AS THE COMMISSION, ACTING PURSUANT TO SAID
SECTION 8(A), MAY DETERMINE.




++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

+INFORMATION CONTAINED HEREIN IS SUBJECT TO COMPLETION OR AMENDMENT. A         +
+REGISTRATION STATEMENT RELATING TO THESE SECURITIES HAS BEEN FILED WITH THE   +
+SECURITIES AND EXCHANGE COMMISSION. THESE SECURITIES MAY NOT BE SOLD NOR MAY  +
+OFFERS TO BUY BE ACCEPTED PRIOR TO THE TIME THE REGISTRATION STATEMENT        +
+BECOMES EFFECTIVE. THIS PROSPECTUS SHALL NOT CONSTITUTE AN OFFER TO SELL OR   +
+THE SOLICITATION OF AN OFFER TO BUY NOR SHALL THERE BE ANY SALE OF THESE      +
+SECURITIES IN ANY STATE IN WHICH SUCH OFFER, SOLICITATION OR SALE WOULD BE    +
+UNLAWFUL PRIOR TO REGISTRATION OR QUALIFICATION UNDER THE SECURITIES LAWS OF  +
+ANY SUCH STATE.                                                               +

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ SUBJECT TO COMPLETION, DATED SEPTEMBER 29, 1997

[ABIOMED LOGO APPEARS HERE]

2,400,000 SHARES

COMMON STOCK

Of the 2,400,000 shares of Common Stock offered hereby, 2,250,000 shares are being offered by ABIOMED, Inc. ("ABIOMED" or the "Company") and 150,000 shares are being offered by the Selling Stockholders. See "Principal and Selling Stockholders." The Company will not receive any of the proceeds from the sale of shares by the Selling Stockholders. On September 26, 1997, the last reported sale price of the Company's Common Stock, as reported on the Nasdaq National Market, was $17.125 per share. See "Price Range of Common Stock." The Company's Common Stock is traded on the Nasdaq National Market under the symbol "ABMD."


THE COMMON STOCK OFFERED HEREBY INVOLVES A HIGH DEGREE OF RISK.
SEE "RISK FACTORS" BEGINNING ON PAGE 6.


THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR HAS THE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.



                                             UNDERWRITING                         PROCEEDS TO
                             PRICE TO        DISCOUNTS AND      PROCEEDS TO         SELLING
                              PUBLIC          COMMISSIONS        COMPANY(1)      STOCKHOLDERS
---------------------------------------------------------------------------------------------
Per Share..............
---------------------------------------------------------------------------------------------
Total (2)..............



(1) Before deducting expenses payable by the Company, estimated at $400,000.
(2) The Company has granted the Underwriters a 30-day option to purchase up to an additional 360,000 shares of Common Stock solely to cover over- allotments, if any. See "Underwriting." If such option is exercised in full, the total Price to Public, Underwriting Discounts and Commissions and Proceeds to Company will be , and , respectively.

The Common Stock is offered by the Underwriters as stated herein, subject to receipt and acceptance by them and subject to their right to reject any order in whole or in part. It is expected that delivery of such shares will be made through the offices of Robertson, Stephens & Company LLC ("Robertson, Stephens & Company"), San Francisco, California, on or about , 1997.

ROBERTSON, STEPHENS & COMPANY UBS SECURITIES

The date of this Prospectus is , 1997


BVS-5000(R) BI-VENTRICULAR ASSIST SYSTEM

THE BVS-5000 PNEUMATIC

[PHOTOGRAPH OF THE ITEMS DESCRIBED                CONSOLE WITH TWO SINGLE-USE
IN THE CAPTION]                                   BVS BLOOD PUMPS MOUNTED ON A
                                                  BEDSIDE STAND. THE BVS-5000
                                                  PROVIDES A PATIENT'S FAILING
                                                  HEART WITH FULL CIRCULATORY
                                                  ASSISTANCE WHILE ALLOWING
                                                  THE HEART TO REST, HEAL AND
                                                  RECOVER ITS FUNCTION.

CERTAIN PERSONS PARTICIPATING IN THIS OFFERING MAY ENGAGE IN TRANSACTIONS THAT STABILIZE, MAINTAIN OR OTHERWISE AFFECT THE PRICE OF THE COMMON STOCK OF THE COMPANY, INCLUDING STABILIZING BIDS, SYNDICATE COVERING TRANSACTIONS AND THE IMPOSITION OF PENALTY BIDS. FOR A DISCUSSION OF THESE ACTIVITIES, SEE "UNDERWRITING."

IN CONNECTION WITH THIS OFFERING, CERTAIN UNDERWRITERS AND SELLING GROUP MEMBERS OR THEIR AFFILIATES MAY ENGAGE IN PASSIVE MARKET MAKING TRANSACTIONS IN THE COMMON STOCK ON THE NASDAQ NATIONAL MARKET IN ACCORDANCE WITH RULE 103 OF REGULATION M UNDER THE SECURITIES EXCHANGE ACT OF 1934. SEE "UNDERWRITING."


NO DEALER, SALES REPRESENTATIVE OR ANY OTHER PERSON HAS BEEN AUTHORIZED TO GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS IN CONNECTION WITH THIS OFFERING OTHER THAN THOSE CONTAINED IN THIS PROSPECTUS, AND, IF GIVEN OR MADE, SUCH INFORMATION OR REPRESENTATION MUST NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED BY THE COMPANY, ANY SELLING STOCKHOLDER OR ANY UNDERWRITER. THIS PROSPECTUS DOES NOT CONSTITUTE AN OFFER TO SELL OR A SOLICITATION OF AN OFFER TO BUY, ANY SECURITIES OTHER THAN THE REGISTERED SECURITIES TO WHICH IT RELATES OR AN OFFER TO, OR A SOLICITATION OF, ANY PERSON IN ANY JURISDICTION IN WHICH SUCH AN OFFER OR SOLICITATION WOULD BE UNLAWFUL. NEITHER THE DELIVERY OF THIS PROSPECTUS NOR ANY OFFER OR SALE MADE HEREUNDER SHALL, UNDER ANY CIRCUMSTANCES, CREATE ANY IMPLICATION THAT THERE HAS BEEN NO CHANGE IN THE AFFAIRS OF THE COMPANY SINCE THE DATE HEREOF OR THAT THE INFORMATION CONTAINED HEREIN IS CORRECT AS OF ANY TIME SUBSEQUENT TO THE DATE HEREOF.


TABLE OF CONTENTS

                                                                       PAGE
                                                                       ----
Summary...............................................................   4
Risk Factors..........................................................   6
Use of Proceeds.......................................................  17
Dividend Policy.......................................................  17
Price Range of Common Stock...........................................  17
Capitalization........................................................  18
Selected Consolidated Financial Data..................................  19
Management's Discussion and Analysis of Financial Condition and
 Results of Operations................................................  20
Business..............................................................  24
Management............................................................  38
Certain Transactions..................................................  41
Principal and Selling Stockholders....................................  42
Description of Capital Stock..........................................  43
Underwriting..........................................................  46
Legal Matters.........................................................  48
Experts...............................................................  48
Available Information.................................................  48
Incorporation of Certain Documents by Reference.......................  49
Index to Consolidated Financial Statements............................ F-1


ABIOMED(R), ABIODENT(R) and the ABIOMED logo are registered service marks of the Company. BVS(R), BVS-5000(R) and PerioTemp(R) are registered trademarks of the Company. Angioflex(TM) and Heart Booster(TM) are trademarks of the Company. Halimeter(R) is a registered trademark of Interscan Corporation. This Prospectus also includes trademarks of companies other than the Company.

As used herein, the term "ABIOMED" or the "Company" includes the Company and its consolidated subsidiaries.

References to "Common Stock" include "Rights" issuable pursuant to that certain Rights Agreement entered into in August 1997 providing for the delivery of a Right along with each share of Common Stock issued by the Company. See "Description of Capital Stock."

3

SUMMARY

This Prospectus contains forward-looking statements which involve risks and uncertainties. The Company's actual results could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including those set forth under "Risk Factors" and elsewhere in this Prospectus.

The following summary is qualified in its entirety by, and should be read in conjunction with, the detailed information and the Consolidated Financial Statements and Notes thereto appearing elsewhere in this Prospectus.

THE COMPANY

ABIOMED, Inc. ("ABIOMED" or the "Company") is a leader in the research and development of cardiac assist and heart replacement technology. The Company developed, manufactures and sells the BVS-5000 ("BVS"), a temporary cardiac assist device designed to provide a patient's failing heart with full circulatory assistance while allowing the heart to rest, heal and recover its function. The BVS is most frequently used in patients whose hearts fail to immediately recover function following heart surgery. The BVS is the only device that can provide full circulatory assistance approved by the United States Food and Drug Administration ("FDA") as a bridge-to-recovery device for the treatment of patients with reversible heart failure.

The Company is developing a battery-powered totally implantable artificial heart ("TAH") intended as a permanent replacement device to assume the full pumping function of both the left and right ventricles of the heart. The TAH is designed for use by patients with irreparably damaged hearts and at risk of death due to acute myocardial infarction ("AMI"), chronic ischemic disease or some form of end-stage congestive heart failure, but whose vital organs otherwise remain viable. Among these combined groups, the Company believes that approximately 60,000 patients per year could benefit from a heart replacement device. The Company is devoting significant resources to accelerate the development of the TAH with the goal to initiate clinical trials of the TAH by the end of the year 2000. There can be no assurance that the Company will be able to successfully complete pre-clinical testing of the TAH and receive FDA approval to begin clinical trials of the TAH in a timely manner, if at all, or that any market will develop for the TAH.

The Company sells the BVS in the United States through direct sales and clinical support teams. Its sales force focuses on sales to new customers, while its clinical support group focuses on training and educating existing customers in order to improve clinical outcomes and increase BVS blood pump usage. The BVS is intended for use in any hospital performing open-chest cardiac surgery, of which there are more than 900 in the United States. As of September 29, 1997, the BVS had been purchased by over 275 medical centers in the United States including many of the largest centers. The Company believes that its installed base of customers provides an opportunity for reorders of the single-use BVS blood pumps as well as a reference base to assist in selling to new accounts.

The Company's goal is to be a leader in the development, manufacture and marketing of mechanical cardiac assist and heart replacement devices that address the varying needs of a wide range of patients. The Company is pursuing a variety of strategies to pursue this objective, including accelerating the development of the TAH, increasing market penetration of the BVS, maintaining and enhancing its technological leadership and pursuing strategic relationships to support its research and commercialization efforts.

Since the Company's inception, United States government agencies, particularly the National Heart, Lung and Blood Institute ("NHLBI"), have provided significant support to the Company's product development efforts. The Company seeks funding from third parties to support its research and development programs and generally limits the use of its own funds until the scientific risk is reduced. In addition, the Company intends to pursue collaborative relationships to develop and commercialize the Company's non- cardiac assist technologies.

The Company is a Delaware corporation. The Company's principal offices are located at 33 Cherry Hill Drive, Danvers, Massachusetts 01923. The Company's telephone number is (978) 777-5410 and its fax number is (978) 777-8411.

4

THE OFFERING

Common Stock Offered by the Company...........  2,250,000 shares
Common Stock Offered by the Selling               150,000 shares
 Stockholders.................................
Common Stock Outstanding after the Offering... 10,513,007 shares (1)
Use of Proceeds............................... For research and development,
                                               expansion of manufacturing
                                               capabilities and other general
                                               corporate purposes. See "Use of
                                               Proceeds."
Nasdaq National Market Symbol................. ABMD

SUMMARY CONSOLIDATED FINANCIAL DATA
(in thousands, except per share data)

                                                                     THREE MONTHS
                                  YEAR ENDED MARCH 31,              ENDED JUNE 30,
                          ----------------------------------------- ---------------
                           1993     1994     1995    1996    1997    1996    1997
                          -------  -------  ------  ------  ------- ------- -------
STATEMENT OF OPERATIONS
 DATA:
Revenues:
  Products..............  $ 1,709  $ 4,648  $6,893  $9,725  $12,311 $ 2,868 $ 4,207
  Contracts.............    1,736    2,027   2,337   3,118    4,151     817   1,829
                          -------  -------  ------  ------  ------- ------- -------
    Total revenues......    3,445    6,675   9,230  12,843   16,462   3,685   6,036
Costs and expenses:
  Cost of products......    2,042    2,211   3,289   3,921    5,361   1,049   1,529
  Research and
   development (2)......    2,097    2,431   2,464   3,218    3,833     864   1,643
  Selling, general and
   administrative.......    3,803    4,553   4,278   5,741    7,068   1,519   2,117
                          -------  -------  ------  ------  ------- ------- -------
    Total costs and
     expenses...........    7,942    9,195  10,031  12,880   16,262   3,432   5,289
                          -------  -------  ------  ------  ------- ------- -------
Income (loss) from
 operations.............   (4,497)  (2,520)   (801)    (37)     200     253     747
Interest and other
 income.................      604      537     449     528      535     130     124
                          -------  -------  ------  ------  ------- ------- -------
Net income (loss).......  $(3,893) $(1,983) $ (352) $  491  $   735 $   383 $   871
                          =======  =======  ======  ======  ======= ======= =======
Net income (loss) per
 share..................  $ (0.60) $ (0.31) $(0.05) $ 0.07  $  0.10 $  0.05 $  0.12
                          =======  =======  ======  ======  ======= ======= =======
Weighted average number
 of shares outstanding..    6,441    6,461   6,512   6,995    7,162   7,206   7,567

                                                     JUNE 30, 1997
                                         -------------------------------------
                                                                PRO FORMA AS
                                         ACTUAL PRO FORMA (3) ADJUSTED (3) (4)
                                         ------ ------------- ----------------
BALANCE SHEET DATA:
Cash, cash equivalents and short-term
 marketable securities.................. $8,766    $24,904        $60,935
Working capital......................... 13,291     29,301         65,332
Total assets............................ 19,715     35,852         71,884
Total stockholders' investment.......... 16,162     32,172         68,203


(1) Based on the number of shares outstanding as of September 26, 1997. Excludes 964,410 shares of Common Stock reserved for issuance upon the exercise of stock options outstanding as of September 26, 1997 at a weighted average exercise price of $10.81 per share. See Note 6 to Consolidated Financial Statements.
(2) Research and development expenses include certain contract costs. See Note 1(e) to Consolidated Financial Statements.
(3) Gives effect to the receipt of net proceeds of approximately $16.0 million from the sale of 1,242,710 shares of Common Stock by the Company in July 1997. See "Certain Transactions" and Note 10 to Consolidated Financial Statements.
(4) Adjusted to reflect the sale of 2,250,000 shares of Common Stock offered by the Company hereby at an assumed public offering price of $17.125 per share and the application of the net proceeds therefrom after deducting the estimated underwriting discounts and commissions and offering expenses payable by the Company. See "Use of Proceeds" and "Capitalization."

Except as otherwise indicated, all information in this Prospectus assumes no exercise of the Underwriters' over-allotment option.

5

RISK FACTORS

This Prospectus contains forward-looking statements which involve risks and uncertainties. The Company's actual results could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including those set forth in the following risk factors and elsewhere in this Prospectus.

In addition to the other information in this Prospectus, the following risk factors should be considered carefully in evaluating the Company and its business before purchasing shares of the Common Stock offered hereby.

DEPENDENCE ON BVS PRODUCT LINE; EARLY STAGE OF BVS MARKET DEVELOPMENT

In the three months ended June 30, 1997 and the fiscal year ended March 31, 1997, sales of the BVS and related products and services represented more than ninety percent of the Company's product revenues. The Company believes that its dependence on the BVS product line is likely to continue for at least the next several years, unless and until the Company successfully develops, obtains regulatory approvals for and sells new products.

The market for the BVS continues to be in the early stage of development. The Company has initially focused its marketing efforts on larger medical centers and hospitals. The commercial success of the BVS will be dependent upon both the Company's ability to sell the BVS to smaller hospitals and medical centers, which generally have more limited financial resources, and the increase of the use of the BVS at those medical centers and hospitals which have purchased the systems. There can be no assurance that the Company will be successful in marketing the BVS. Advances in medical technology, biotechnology and pharmaceuticals may reduce the size of the potential markets for the Company's products or render those products obsolete. Failure of the Company to expand the market for and use of the BVS would have a material adverse effect on its business, financial condition and results of operations. See "Business--Marketing and Sales."

UNCERTAINTY OF PRODUCT DEVELOPMENT AND CLINICAL TRIALS

The Company has developed and markets a limited number of products and believes that its future success will in large part be dependent upon its ability to develop and market innovative new products, such as the TAH. The successful development of these products presents enormous challenges. The Company must demonstrate that the TAH, which is being designed to assume the full pumping function of both the left and right ventricles of the heart, can operate effectively and reliably within a patient over an extended period. For many years, the Company and others have been attempting to develop products that meet these criteria and have not yet been successful. Before obtaining regulatory approvals for the commercial sale of any of its products under development, the Company must demonstrate through pre-clinical studies and clinical trials that the product is safe and effective. Initial pre-clinical testing of the TAH and other products being developed by the Company will be conducted in simulated environments and animal models to demonstrate safety and effectiveness over an extended period of time before they are permitted to be clinically tested in humans. There can be no assurance that the Company will be able to successfully complete pre-clinical testing of the TAH or other products being developed by the Company and receive FDA approval to initiate clinical trials of such products in a timely manner, if at all. Moreover, pre- clinical trials may not be predictive of results that will be obtained in clinical trials. Any significant delays in, or termination of, pre-clinical trials of the Company's products under development would have a material adverse effect on the Company's business, financial condition and results of operations.

Clinical trials for the Company's cardiac assist and heart replacement products will be conducted with patients who are critically ill. During the course of treatment, these patients may die or suffer other adverse medical effects for reasons that may not be related to the product being tested but which can nevertheless affect clinical trial results. A number of companies in the medical device industry have suffered significant

6

setbacks in advanced clinical trials, even after promising results in earlier trials. Clinical trials of the Company's TAH and other products under development may be delayed or terminated as a result of many factors, and there can be no assurance that such delays or terminations will not occur. One such factor is the rate of enrollment of patients, which generally varies throughout the course of a clinical trial and which depends on the size of the potential patient population, the number of clinical trial sites, the proximity of the patients to clinical trial sites, the eligibility criteria for the trial and the existence of competitive clinical trials. The Company cannot control the rate at which patients present themselves for enrollment, and there can be no assurance that the rate of patient enrollment will be consistent with the Company's expectations or be sufficient to enable clinical trials of the Company's products under development to be completed in a timely manner, if at all. Any significant delays in, or termination of, clinical trials of the Company's products under development would have a material adverse effect on the Company's business, financial condition and results of operations.

In addition, the Company's product development will be subject to numerous other risks associated with new product development, including unanticipated delays, expenses, technical problems or other difficulties that could result in the abandonment or substantial change in the design, development and commercialization of these new products. Given the uncertainties inherent with product development and introduction, there can be no assurance that any of the Company's products under development will demonstrate sufficient safety and efficacy to obtain the requisite regulatory approvals, on a timely basis and within budget, if at all, or that any of these products will be commercially successful if such approvals are obtained. See "Business--ABIOMED Products and Products under Development."

ANTICIPATED FUTURE LOSSES

The Company plans to use its own resources to fund the further development of the TAH in amounts significantly in excess of the funding provided under the Company's development contract for the TAH with the NHLBI ("TAH Contract"). The Company estimates that the development of the TAH, including conducting pre-clinical and clinical studies and obtaining regulatory approvals, will require substantial funds. As a result, the Company believes that it may again incur losses. The amount and duration of these losses will depend upon a number of factors, including the Company's ability to increase sales and profitability of its present products, to develop and obtain regulatory approvals for new products and product enhancements, and to successfully manufacture and market these new products and enhancements, as well as the timing and extent of the Company's spending related to product development and the timing of government appropriations related to the Company's NHLBI contracts. The Company anticipates that its spending under the TAH Contract will, beginning in the quarter ending September 30, 1997, exceed the amount which the government has currently appropriated for that contract. There can be no assurance that the government will appropriate any additional amounts under the TAH Contract or any of the Company's other government contracts on a timely basis, if at all. See "Use of Proceeds" and "Management's Discussion and Analysis of Financial Condition and Results of Operations."

COMPLEX MANUFACTURING; HIGH-QUALITY REQUIREMENTS

The nature of the Company's products requires high-quality manufacturing. The Company's manufacturing and quality testing processes and procedures are highly dependent on the diligence and experience of the Company's personnel. To the extent that the Company's manufacturing volumes expand or the Company begins the manufacture of new products, this dependence on personnel will likely increase. In addition, the manufacture of the blood contacting surfaces of the Company's products requires a high degree of precision. These surfaces are manufactured from polyurethane-based materials. The quality and composition of polyurethane-based products can vary significantly based on numerous factors including humidity, temperature, material content and air flow during the manufacturing process. The Company's products also incorporate plastic components for non-blood contacting surfaces. The Company relies on third-party vendors to provide these components to the Company's specifications. The Company is not able to fully inspect the quality of all vendor supplied components and, therefore, relies on its vendors with respect to the

7

quality of these components. Once the plastic-based components of the Company's products have been assembled, accessibility for inspection is limited. If a defect is detected in as few as one of the Company's products, or in one component of a Company product, it can result in the recall or restriction on sale of products. Once assembled, in most cases, the Company's blood contacting components cannot be reworked for human use. The manufacturing lead times for parts and assemblies, particularly the polyurethane-based components, can take many weeks from the date that all materials and components are received by the Company. In addition, vendor lead times for materials and components of the Company's products vary significantly, with lead times for certain materials and components exceeding six months.

The Company is planning to expand its manufacturing facility for the BVS during the next twelve months. There can be no assurance that the products manufactured in the expanded facility will be manufactured at the same cost and quality as the BVS is currently being manufactured. In addition, to the extent that the Company's products under development have been manufactured, they have been manufactured as prototypes with, at most, pilot-scale production. The Company's products under development are likely to involve additional manufacturing complexities and high quality requirements. There can be no assurance that the Company will be able to increase production of the BVS or manufacture future products, if developed and approved, in commercial quantities on a consistent and timely basis, with acceptable cost and quality. The inability to manufacture current and future products in sufficient quantities in a timely manner, and with acceptable cost and quality, would have a material adverse effect on the Company's business, financial condition and results of operations. See "Business--Manufacturing."

RISK OF MARKET WITHDRAWAL OR PRODUCT RECALL

Complex medical devices, such as the BVS and other of the Company's products under development, can experience performance problems that require review and possible corrective action by the manufacturer. Similar to many other medical device manufacturers, the Company periodically received reports from users of its products relating to performance difficulties they have encountered. The Company expects that it will continue to receive customer reports regarding the performance and use of the BVS. There can be no assurance that component failures, manufacturing errors or design defects that could result in an unsafe condition or injury to the patient will not occur. Certain of these failures or defects have been deemed sufficiently serious by the Company to result in recalls of products associated with certain manufacturing lots or containing certain components, including a recall of certain BVS blood pumps initiated in late 1996. Not all of the products subject to this recall have been returned to the Company. Any product problems could result in market withdrawals or recalls of products, voluntarily or required, which could have a material adverse effect on the Company's business, financial condition and results of operations. In addition, there can be no assurance that a product recall will result in the recovery of all defective products or prevent customers from using these products. The use of a defective product could result in injury to a patient and significant liability to the Company which could have a material adverse effect on its business, financial condition and results of operations. See "Management's Discussion and Analysis of Financial Condition and Results of Operations."

FLUCTUATIONS AND UNPREDICTABILITY OF OPERATING RESULTS

The Company's annual and quarterly operating results have fluctuated and the Company expects these fluctuations to continue. Significant annual and quarterly fluctuations in the Company's results of operations may be caused by, among other factors, the overall state of health care and cost containment efforts, economic conditions in the Company's markets, the expense and timing of the Company's development efforts for a particular product or product enhancement, the timing of regulatory actions, the potential need to recall or rework products from time to time, timing of government appropriations related to the Company's research contracts and grants, the timing of or changes in third-party reimbursement policies for the Company's products, the timing of expenditures in anticipation of future sales, variations in the Company's product mix and component costs, the availability of components, the timing of customer orders, adjustments of delivery schedules to accommodate customers, inventory levels of products at customers (including inventory at

8

distributors), changes in the government's funding policies under the Company's existing contracts, pricing and other competitive conditions, and the timing of the announcement, introduction and delivery of new products and product enhancements by the Company and its competitors. Customers may also cancel or reschedule shipments, and production difficulties could delay shipments. The price for the BVS console is significantly higher than for the single-use blood pumps. As a result, variations in the number and timing of consoles sold have a disproportionate effect on the Company's revenues and results of operations. The Company also believes that BVS sales may be somewhat seasonal, with reduced sales in the summer months, reflecting hospital personnel and physician vacation schedules. Beginning in fiscal 1998, the Company anticipates potentially significant annual and quarterly fluctuations in contract revenues and research and development costs associated with the development of the TAH due to the need for additional government appropriations under the TAH Contract and to increased levels of Company spending. See "Management's Discussion and Analysis of Financial Condition and Results of Operations."

MARKETS FOR PRODUCTS UNDER DEVELOPMENT UNPROVEN

Most of the Company's products under development, including the TAH, are targeting new and unproven markets. There can be no assurance that the TAH or other products under development by the Company will gain any degree of market acceptance among physicians, medical centers and third party payors, including managed care organizations, even if necessary regulatory approvals and reimbursement are obtained. As a result, it is likely that the Company's evaluation of the potential markets for these products will materially vary with time. In addition, the effective use of these products will likely require development of new surgical techniques by well-trained physicians, which will initially limit the market for the Company's products. Physicians, patients and society as a whole may have ethical concerns or be reluctant to accept medical devices designed to replace the heart. The timing and amount of reimbursement, if any, by third-party payors for the use of these products, if developed, will also have a significant impact on the market for these products. Other companies may also introduce products or technologies which will compete with these products, reduce the market for these products, or render these products obsolete. There can be no assurance that the Company will be able to market successfully any of its products under development, if and when these products are developed. Failure to do so would have a material adverse effect on the Company's business, financial condition and results of operations. See "Business--Marketing and Sales."

DEPENDENCE ON KEY PERSONNEL; RISKS ASSOCIATED WITH GROWING NUMBER OF EMPLOYEES

The Company is highly dependent on the principal members of its scientific, sales, and management staff, the loss of whose services could have a material adverse effect on the Company's business, financial condition and results of operations. Competition among medical device companies for highly skilled scientific, sales and management personnel is intense. There can be no assurance that the Company will be able to attract and retain all personnel necessary for the development of its business. Failure to do so could have a material adverse effect on its business, financial condition and results of operations.

The Company has recently experienced a significant increase in the number of its full-time employees, from 79 at April 1, 1996 to 166 at September 29, 1997. Moreover, the Company intends to continue to add a significant additional number of employees to support its development and expanding manufacturing, marketing and sales efforts. The expansion of the Company's personnel has placed additional demands upon, and may significantly strain, the Company's management, financial systems and other resources. There can be no assurance that the Company will be able to successfully manage its growing number of employees. Failure to do so would have a material adverse effect on the Company's business, financial condition and results of operations.

COMPETITION AND TECHNOLOGICAL CHANGE

Competition in the cardiac assist market is intense and subject to rapid technological change and evolving industry requirements and standards. Many of the companies developing or marketing cardiac assist products

9

have substantially greater financial, product development, sales and marketing resources and experience than the Company. These competitors may develop superior products or products of similar quality at the same or lower prices. Moreover, there can be no assurance that improvements in current or new technologies will not make them technically equivalent or superior to the Company's products in addition to providing cost or other advantages. Other advances in medical technology, biotechnology and pharmaceuticals may reduce the size of the potential markets for the Company's products or render those products obsolete.

The BVS is the only device that can provide full circulatory assistance approved by the FDA as a bridge-to-recovery device for the treatment of patients with reversible heart failure. However, the Company is aware of at least one other company, Thoratec Laboratories Corporation, seeking approval of a temporary cardiac assist device to address this market. Approval by the FDA of products that compete directly with the BVS would increase competitive pricing and other pressures and could have a material adverse effect on the Company's business, financial condition and results of operations.

The Company is aware of other artificial heart development efforts in the United States, Canada, Europe and Japan. A team comprised of Pennsylvania State University and 3M Corporation, Inc. has been developing a heart replacement device for many years with significant NHLBI support. There are a number of companies, including Thermo Cardiosystems, Inc. and Novacor, a division of Baxter International, Inc., which are developing permanent cardiac assist products, including implantable left ventricular assist devices ("LVADs") and miniaturized rotary ventricular assist devices, that may address markets that overlap with those targeted by the Company's TAH.

The Company's customers frequently have limited budgets. As a result, the Company's products compete against the broad range of medical devices for these limited funds. The Company's success will depend in large part upon its ability to enhance its existing products and to develop new products to meet regulatory and customer requirements and to achieve market acceptance. The Company believes that important competitive factors with respect to the development and commercialization of its products include the relative speed with which it can develop products, establish clinical utility, complete clinical testing and regulatory approval processes, obtain reimbursement and supply commercial quantities of the product to the market. There can be no assurance that the Company will be able to compete successfully or that competition will not have a material adverse effect on the Company's business, financial condition and results of operations. See "Business--Competition."

GOVERNMENT REGULATION

Clinical testing, manufacture and sale of the Company's products and products under development, including the BVS and the TAH, are or will be subject to regulation by the FDA and corresponding state and foreign regulatory agencies. Noncompliance with applicable requirements can result in, among other things, fines, injunctions, civil penalties, recall or seizure of products, total or partial suspension of production, failure of the government to grant pre-market clearance or pre-market approval for devices, withdrawal of marketing approvals and criminal prosecution. The FDA also has the authority to request repair, replacement or refund of the cost of any device manufactured or distributed by the Company.

Any devices, including the BVS, that are manufactured or distributed by the Company pursuant to FDA clearances or approvals are subject to pervasive and continuing regulation by the FDA and certain state agencies. Manufacturers of medical devices for marketing in the United States are required to adhere to the FDA's Quality System Regulation and must also comply with Medical Devices Reporting requirements that a firm report to the FDA any incident in which its product may have caused or contributed to a death or serious injury, or in which its product malfunctioned and, if the malfunction were to recur, it would be likely to cause or contribute to a death or serious injury. Labeling and promotional activities are subject to scrutiny by the FDA and, in certain circumstances, by the Federal Trade Commission. Current FDA enforcement policy prohibits the marketing of approved medical devices for unapproved uses. The Company is subject to routine inspection by the FDA and certain state agencies for compliance with the Quality System Regulation and Medical Device Reporting requirements, as well as other applicable regulations.

10

In addition, the FDA requires that manufacturers of certain devices, including the BVS, conduct postmarket surveillance studies after receiving approval of a Pre-Market Approval ("PMA") application. The primary purpose of required postmarket surveillance is to provide an early warning system to alert the health care community to any potential problems with a device within a reasonable time of the initial marketing of the device. Postmarket surveillance provides clinical monitoring of the early experiences with the device once it is distributed in the general population under actual conditions of use.

The Company is also subject to regulation in each of the foreign countries in which it sells its products. Many of the regulations applicable to the Company's products in these counties are similar to those of the FDA. The Company believes that foreign regulations relating to the manufacture and sale of medical devices are becoming more stringent. The European Union has adopted regulations requiring that medical devices comply with the Medical Device Directive by June 15, 1998, which includes ISO-9001 and CE certification. The Company's BVS currently has German MedGV approval but is not yet certified for ISO-9001 compliance. The Company is working to obtain ISO-9001 and independent CE certification for its BVS facility. There can be no assurance that the Company will obtain such certification in a timely manner, if at all. Unless ISO and CE certification are obtained, the Company's sale of the BVS into the European Union may be restricted. Many manufacturers of medical devices, including the Company, have often relied on foreign markets for the initial commercial introduction of their products. The more stringent foreign regulatory environment could make it more difficult, costly and time consuming for the Company to pursue this strategy for new products.

Any FDA, foreign or state regulatory approvals or clearances, once obtained, can be withdrawn or modified. Delay in the Company obtaining, or inability of the Company to obtain and maintain, any necessary United States or foreign clearances or approvals for new or existing products or product enhancements, or cost overruns resulting from these regulatory requirements, would have a material adverse effect on the Company's business, financial condition and results of operations. See "Business--Government Regulation."

RELIANCE ON GOVERNMENT CONTRACTS

The Company generally relies on external funding for its basic research and development, primarily through government research contracts and grants. Such funding has been obtained for the initial development of most of the Company's current products and products under development. In particular, in September 1996, the Company was awarded by the NHLBI a four-year $8.5 million extension to its TAH Contract, and in September 1995 the Company was awarded a five-year $4.3 million contract from the NHLBI for the development of the Company's Heart Booster. As of June 30, 1997, the Company's total backlog of government contracts and grants was $8.9 million. Such contracts and grants are not expected to be sufficient to commercialize the underlying products, and for certain products, including the TAH, the cost of product development in excess of the contract value is expected to be significant. The Company's strategy is to continue to seek government contracts and grants to support development efforts. Funding for the Company's government research and development contracts is subject to government appropriation, and all of these contracts contain provisions which make them terminable at the convenience of the government. There can be no assurance that the government will not terminate or reduce or delay the funding for any of the Company's contracts. In addition, there can be no assurance that the Company will be successful in obtaining any new government contracts or further extensions to existing contracts. A significant delay or reduction of funding under the Company's government contracts could have a material adverse effect on the Company's business, financial condition and results of operations. See "Management's Discussion and Analysis of Financial Conditions and Results of Operations" and "Business--ABIOMED Products and Products under Development" and "--Strategic Relationships."

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DEPENDENCE ON LIMITED SOURCES OF SUPPLY

The Company relies on outside vendors to supply certain components used in the BVS and in its products under development. Certain of the components of the BVS are supplied by sole source vendors or are custom made for the Company. From time to time, suppliers of certain components of the BVS have indicated that they intend to discontinue, or have discontinued, making such components. In addition, certain of these components are supplied from single sources due to quality considerations, costs or constraints imposed by regulatory authorities. There are relatively few additional sources of supply for such components and establishing additional or replacement suppliers for such components cannot be accomplished quickly and may require FDA approval. In the past, certain suppliers have announced that, due to government regulation or in an effort to reduce potential product liability exposure, they intend to limit or terminate sales of certain products to the medical industry. There can be no assurance that, if such an interruption were to occur, the Company would be able to find suitable alternative supplies at reasonable prices or would be able to obtain requisite regulatory approvals in a timely manner, if at all. Similarly, when and if the Company reaches the clinical testing stage of its products under development, it may find that certain components become more difficult to source from outside vendors due to the product liability risk perceived by those vendors. The Company's inability to obtain acceptable components in a timely manner or to find suitable replacements at an acceptable cost would have a material adverse effect on the Company's business, financial condition and results of operations. See "Business--Manufacturing."

FUTURE CAPITAL NEEDS AND UNCERTAINTY OF ADDITIONAL FUNDING

The Company is working on the research and development of several long-term projects and is placing increased emphasis on development of the TAH, which will result in significantly increased internally funded research and development expenditures. These costs include costs of pre-clinical trials and regulatory approvals. The Company estimates that the cost of developing the TAH and other products will be significant. These costs may include costs related to pre-clinical and clinical trials and regulatory approvals. The Company estimates that it will require significant additional funds in order to complete the development and achieve regulatory approvals of the TAH and other products under development. Generally, estimates of long-term project costs are extremely imprecise and cost overruns are common. As a result, there can be no assurance that the Company will not require significantly more resources to complete the development of the TAH and its other products. The Company plans to fund this effort through a combination of the TAH Contract, proceeds from the offering, existing resources, the possible sales of additional securities and cash flow from sales of its existing products. Even if the Company does not experience cost overruns, there can be no assurance that the Company will be able to obtain sufficient funds to complete the development of the TAH and other products. Moreover, the Company may require additional funds to commence the manufacture and marketing of the TAH or any of the Company's other products under development in commercial quantities, if and when approved or cleared by the regulatory authorities. Failure of the Company to obtain any required additional funding could delay product development and otherwise materially and adversely affect the business of the Company. There can be no assurance that the Company will be able to obtain additional funding on favorable terms, if at all. See "Use of Proceeds" and "Management's Discussion and Analysis of Financial Condition and Results of Operations."

DEPENDENCE ON THIRD-PARTY REIMBURSEMENT

The Company's BVS product is, and most of its products under development are intended to be, sold to medical institutions. Medical institutions and their physicians typically seek reimbursement for the use of these products from third-party payors, including Medicare, Medicaid, private health insurers and managed care organizations. As a result, market acceptance of the Company's current and proposed products may depend in large part on the extent to which reimbursement is available to medical institutions and their physicians for use of the Company's products.

The level of reimbursement provided by United States and foreign third-party payors varies according to a number of factors, including the medical procedure category, payor, location, outcome and cost. In the

12

United States, many private health care insurance carriers follow the recommendations of the Health Care Finance Administration ("HCFA"), which establishes guidelines for the reimbursement of health care providers treating Medicare and Medicaid patients. Internationally, medical reimbursement systems vary significantly. In certain countries, medical center budgets are fixed regardless of levels of patient treatment. In other countries, such as Japan, reimbursement from government or third party payors must be applied for and approved. As of the date of this Prospectus, under HCFA guidelines, Medicare reimburses medical institutions for Medicare patients based on the category of surgical procedures in which the BVS is used and incrementally reimburses physicians for the use of the BVS. Medicare does not, however, currently reimburse medical institutions for the incremental cost of using the BVS above the amount allowed for the reimbursement category of the surgical procedure. Certain private health insurers and managed care providers provide incremental reimbursement to both the medical institutions and their physicians. The Company is currently petitioning HCFA to assign a higher paying reimbursement category whenever the BVS is used. In October 1995, HCFA established a special "ICD-9" code for the BVS in an effort to more clearly track and evaluate hospital and physician costs associated specifically with the BVS compared to current reimbursement levels, so that HCFA can determine the appropriate category and level of reimbursement. There can be no assurance that HCFA will reassign the BVS to a higher paying category in a timely manner, if at all.

No reimbursement levels have been established for the Company's products under development, including the TAH. Prior to approving coverage for new medical devices, most third-party payors require evidence that the product has received FDA approval or clearance for marketing, is safe and effective and not
experimental or investigational, and is medically necessary and appropriate for the specific patient for whom the product is being used. Increasing numbers of third-party payors require evidence that the procedures in which the products are used, as well as the products themselves are cost-effective. There can be no assurance that the Company's products under development will meet these criteria, that third-party payors will reimburse physicians and medical institutions for the use of the products or that the level of reimbursement will be sufficient to support the widespread use of the products. Furthermore, there can be no assurance that third-party payors will continue to provide reimbursement for the use of BVS or that such payors will not reduce the current level of reimbursement for the product. Failure to achieve adequate reimbursement for its current or proposed products would have a material adverse effect on the Company's business, financial condition and results of operations.

POTENTIAL INADEQUACY OF PRODUCT LIABILITY INSURANCE

The Company's business involves the risk of product liability claims inherent in the manufacture and marketing of life support systems. There are many factors beyond the control of the Company that could result in the failure of the BVS to sustain the life of a patient, the most important of which is the condition of the patient prior to the use of the product. As a result, many of the patients using the BVS do not survive. In addition, the effectiveness of the Company's products could be adversely affected by the reliability of the physicians, nurses and technicians using and monitoring the use of the product, and the maintenance of the product by the Company's customers. The failure of the BVS or any other life support system under development by the Company to save a life could give rise to product liability claims and result in negative publicity that could have a material adverse effect on the Company's business, financial condition and results of operations. The Company currently maintains product liability insurance, subject to certain deductibles and exclusions. There can be no assurance that this insurance will be sufficient to protect the Company from product liability claims, or that product liability insurance will continue to be available to the Company at a reasonable cost, if at all.

The risk of product liability claims against the Company may increase as the Company introduces new products under development, particularly products such as the TAH intended for permanent life support. The TAH will have a finite life and could cause unintended complications to other organs. The eventual failure of the TAH could give rise to product liability claims, regardless of whether the TAH has extended or improved the quality of the patient's life beyond that expected without the use of the TAH. As a result of the additional

13

product liability risks that will be associated with the TAH and other products under development by the Company, there can be no assurance that the Company will be able to secure product liability insurance for these products, when and if developed, or that such insurance will be sufficient to protect the Company at an acceptable cost. The failure of the Company to be able to obtain adequate product liability insurance, if any, for these products could have a material adverse effect on its business, financial condition and results of operations.

DEPENDENCE ON PATENTS AND PROPRIETARY RIGHTS

The Company's business depends significantly upon its proprietary technology. The Company relies on a combination of trade secret laws, patents, copyrights, trademarks and confidentiality agreements and other contractual provisions to establish, maintain and protect its proprietary rights, all of which afford only limited protection. There can be no assurance that others will not independently develop substantially equivalent proprietary information and techniques or otherwise gain access to the Company's trade secrets or disclose such technology or that the Company can meaningfully protect its trade secrets.

The Company has been issued or allowed 22 patents and has pending three patent applications in the United States. The Company has obtained or applied for corresponding patents for certain of these patents and patent applications in a limited number of foreign countries. These patents relate to the BVS and certain of its products under development including the TAH. The Company's United States patents expire at various times from 2003 to 2016. There can be no assurance that the Company's pending patent applications or any future applications will be approved, that any patents will provide the Company with competitive advantages or will not be challenged by third parties, or that the patents of others will not render the Company's patents obsolete or otherwise have an adverse effect on the Company's ability to conduct business. Because foreign patents may afford less protection under foreign law than is available under United States patent law, there can be no assurance that any such patents issued to the Company will adequately protect the Company's proprietary information. Others may have filed and may file patent applications in the future that are similar or identical to those of the Company. To determine the priority of inventions, the Company may have to participate in interference proceedings declared by the United States Patent and Trademark Office or opposition proceedings before a foreign patent office that could result in substantial cost to the Company. No assurance can be given that any such interfering patent or patent application will not have priority over patent applications filed on behalf of the Company or that the Company will prevail in any opposition proceeding.

The medical device industry is characterized by a large number of patents and by frequent and substantial intellectual property litigation. There can be no assurance that the Company's products and technologies do not infringe any patents or proprietary rights of third parties. The Company may in the future be notified that it may be infringing intellectual property rights possessed by others. Any intellectual property litigation would be costly and could divert the efforts and attention of the Company's management and technical personnel, which could have a material adverse effect on the Company's business, financial condition and results of operations. There can be no assurance that infringement claims will not be asserted in the future or such assertions, if proven to be true, will not prevent the Company from selling its products or materially and adversely affect the Company's business, financial condition and results of operations. If any such claims are asserted against the Company's intellectual property rights, it may seek to enter into a royalty or licensing arrangement. There can be no assurance, however, that a license will be available on reasonable terms, or at all. The Company could decide, in the alternative, to resort to litigation to challenge such claims or to design around the patented technology. Such actions could be costly and would divert the efforts and attention of the Company's management and technical personnel, which would materially and adversely affect the Company's business, financial condition and results of operations. See "Business-- Patents and Proprietary Rights."

CONTROL BY MANAGEMENT

Upon completion of this offering, the Company's directors, officers and their affiliates will beneficially own approximately 27.2% of the outstanding Common Stock of the Company (as determined in accordance with the rules of the Securities and Exchange Commission). As a result, these stockholders will be able to

14

exert substantial influence over actions requiring stockholder approval, including the election of directors, amendments to the Company's Restated Certificate of Incorporation, mergers, sales of assets or other business acquisitions or dispositions. See "Principal and Selling Stockholders."

ANTI-TAKEOVER PROVISIONS; RIGHTS AGREEMENT; ISSUANCE OF PREFERRED STOCK

The Company's Restated Certificate of Incorporation ("Certificate of Incorporation") and Amended and Restated By-laws ("By-laws") contain certain provisions that could have the effect of deterring certain mergers, tender offers, proxy contests or other future takeover attempts which holders of some or even a majority of the outstanding stock believe to be in their best interest, and may make removal of management more difficult even if such removal would be deemed to be beneficial to stockholders generally. These provisions could limit the price that certain investors might be willing to pay in the future for shares of the Company's Common Stock. In addition, the Company has adopted a Rights Agreement, pursuant to which the Company has distributed to its stockholders rights to purchase shares of junior participating preferred stock ("Rights Agreement"). Upon certain triggering events, such rights become exercisable to purchase the Company's Common Stock at a price substantially discounted from the then applicable market price of the Company's Common Stock. The Rights Agreement could generally discourage a merger or tender offer involving the securities of the Company that is not approved by the Company's Board of Directors by increasing the cost of effecting any such transaction and, accordingly, could have an adverse impact on stockholders who might want to vote in favor of such merger or participate in such tender offer. In addition, shares of the Company's Class B Preferred Stock ("Preferred Stock") may be issued in the future without further stockholder approval and upon such terms and conditions, and having such rights, privileges and preferences, as the Board of Directors may determine. The rights of the holders of Common Stock will be subject to, and may be adversely affected by, the rights of any holders of Preferred Stock that may be issued in the future. The issuance of Preferred Stock, while providing desirable flexibility in connection with possible acquisitions and other corporate purposes, could have the effect of making it more difficult for a third party to acquire, or of discouraging a third party from acquiring, a majority of the outstanding voting stock of the Company. The Company has no present plans to issue any shares of Preferred Stock. The Certificate of Incorporation and By-laws impose various procedural and other requirements that could make it more difficult for stockholders to effect certain corporate actions. See "Description of Capital Stock--Anti-takeover Effect of Provisions of the Certificate of Incorporation and By-laws, Rights Distribution and Delaware Law."

POSSIBLE VOLATILITY OF SHARE PRICE

There has been a history of significant volatility in the market price for shares of the Common Stock and shares of other companies in the medical products and biomedical technology fields. Factors such as the announcement of new products and the achievement of developmental and regulatory milestones by the Company or its competitors have caused and could cause the price of the Common Stock to fluctuate significantly. Moreover, although there has been a public trading market for the Common Stock since 1987, there have been periods of limited trading activity resulting in further volatility of the stock price. Additionally, the spread between the ask and bid prices for the Common Stock on the Nasdaq National Market System has been relatively wide, potentially discouraging investor trades in the Common Stock. Further, in the event that in some future fiscal quarter the Company's revenues were below the expectations of public market analysts and investors, the price of the Common Stock could be materially adversely affected. In addition, stock markets have experienced extreme price and volume trading volatility in recent years. This volatility has had a substantial effect on market prices of securities of many medical technology companies for reasons frequently unrelated or disproportionate to the operating performance of the specific companies. These broad market fluctuations may adversely affect the market price of the Common Stock. See "Price Range of Common Stock."

SHARES ELIGIBLE FOR FUTURE SALE

Sales of a substantial number of shares of Common Stock in the public market following this offering (pursuant to Rule 144 or otherwise), as well as sales of shares issued upon exercise of employee stock options, could adversely affect the prevailing market price of the Common Stock and impair the Company's ability to

15

raise additional capital through the sale of equity securities. Of the approximately 8,263,007 shares of Common Stock outstanding at September 26, 1997, approximately 5,390,253 shares are eligible for resale in the public market without restriction and approximately 1,474,198 shares are eligible for resale subject to the provisions of Rule 144. The remaining 1,398,556 shares of Common Stock are "restricted securities" within the meaning of Rule 144, of which 2,000 shares and 1,396,556 shares will not be eligible for resale until January and July 1998, respectively, the expiration of the one-year holding period under Rule 144, and then only in accordance therewith. In addition, there are 964,410 shares subject to outstanding options, which shares have been registered on Form S-8 and will therefore be subject to resale in the public market either without restriction or subject to the provisions of Rule
144. The holders of 1,396,556 shares of Common Stock have certain registration rights, commencing on July 14, 1998. The Company's executive officers, directors, Genzyme Corporation ("Genzyme") and each of the Selling Stockholders who, in the aggregate hold approximately 2,872,754 shares of Common Stock (2,722,754 shares of Common Stock after the sale of shares of Common Stock by the Selling Stockholders in the offering) have agreed that, for a period of 90 days from the date of this Prospectus, subject to certain limited exceptions, they will not, directly or indirectly, without the prior written consent of Robertson, Stephens & Company LLC, sell, offer, contract to sell, pledge, grant any option to purchase or otherwise dispose of any shares of Common Stock or any securities convertible into or exchangeable for, or any rights to purchase or acquire, Common Stock held by them, thereafter acquired by them or which may be deemed to be beneficially owned by them. See "Certain Transactions" and "Underwriting."

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USE OF PROCEEDS

The net proceeds to the Company from the sale of the 2,250,000 shares of Common Stock offered by the Company hereby are estimated to be $36.0 million ($41.9 million if the Underwriters' over-allotment option is exercised in full), assuming an offering price of $17.125 per share and after deducting estimated underwriting discounts and commissions and offering expenses payable by the Company. The Company will not receive any proceeds from the sale of shares of Common Stock by the Selling Stockholders.

The Company expects to use the net proceeds from this offering for research and development, expansion of its manufacturing capabilities and other general corporate purposes. In particular, the Company expects that a substantial portion of the net proceeds will be used to support the TAH and other development efforts, although there can be no assurance that the net proceeds will be so used. The Company may also use a portion of the net proceeds for strategic acquisitions of businesses, products or technologies complementary to the Company's business. The Company does not have any commitments to make any such acquisitions and has not allocated a specific amount of the net proceeds for this purpose. Pending such uses, the Company plans to invest the net proceeds of the offering in short-term, interest-bearing investment-grade securities.

DIVIDEND POLICY

The Company has never declared or paid cash dividends on its capital stock and does not plan to pay any cash dividends in the foreseeable future. The Company's current policy is to retain all of its earnings to finance future growth.

PRICE RANGE OF COMMON STOCK

The Company's Common Stock is traded on the Nasdaq National Market under the symbol "ABMD." The following table sets forth, for the periods indicated, the high and low sales prices per share of Common Stock, as reported by the Nasdaq National Market.

                                                                  HIGH     LOW
                                                                 ------- -------
FISCAL YEAR ENDED MARCH 31, 1996
First Quarter................................................... $ 9     $ 6
Second Quarter..................................................  13 1/4   6 7/8
Third Quarter...................................................  16       8 3/4
Fourth Quarter..................................................  15 1/4  11 1/2
FISCAL YEAR ENDED MARCH 31, 1997
First Quarter...................................................  18      12 1/2
Second Quarter..................................................  18 1/4  10 1/8
Third Quarter...................................................  18 1/4  11 1/2
Fourth Quarter..................................................  13 1/4   9 1/2
FISCAL YEAR ENDING MARCH 31, 1998
First Quarter...................................................  16       9 1/2
Second Quarter (through September 26, 1997).....................  19      13 1/2

The last reported sale price of the Common Stock on the Nasdaq National Market on September 26, 1997 was $17.125 per share. As of September 26, 1997, there were approximately 340 holders of record of the Company's Common Stock, including multiple beneficial holders at depositories, banks and brokers listed as a single holder in the street name of each respective depository, bank or broker.

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CAPITALIZATION

The following table sets forth as of June 30, 1997 (i) the unaudited actual capitalization of the Company, (ii) the pro forma capitalization of the Company, giving effect to the receipt of net proceeds of approximately $16.0 million from the sale of 1,242,710 shares of Common Stock by the Company in July 1997 and (iii) such pro forma capitalization as adjusted to reflect the receipt of the estimated net proceeds from the sale of 2,250,000 shares of Common Stock being offered by the Company hereby at an assumed offering price of $17.125 per share and after deducting estimated underwriting discounts and commissions and offering expenses payable by the Company.

                                                        JUNE 30, 1997
                                                --------------------------------
                                                                      PRO FORMA
                                                 ACTUAL   PRO FORMA  AS ADJUSTED
                                                --------  ---------  -----------
                                                        (in thousands)
Long-term debt................................. $    --   $    --      $   --
                                                --------  --------     -------
Stockholders' investment (1):
  Class B Preferred Stock, $0.01 par value,
   1,000,000 shares authorized; no shares
   issued and outstanding; no shares issued and
   outstanding pro forma; no shares issued and
   outstanding pro forma as adjusted...........      --        --          --
  Common Stock, $.01 par value, 25,000,000
   shares authorized; 7,017,872 shares issued
   and outstanding; 8,260,582 shares issued and
   outstanding pro forma and 10,513,007 shares
   issued and outstanding pro forma as
   adjusted....................................       70        83         105
  Additional paid-in capital...................   37,236    53,233      89,242
  Accumulated deficit..........................  (21,144)  (21,144)    (21,144)
                                                --------  --------     -------
    Total stockholders' investment.............   16,162    32,172      68,203
                                                --------  --------     -------
      Total capitalization..................... $ 16,162  $ 32,172     $68,203
                                                ========  ========     =======


(1) Based on the number of shares outstanding as of June 30, 1997. Excludes 919,185 shares of Common Stock reserved for issuance upon the exercise of stock options outstanding as of June 30, 1997 at a weighted average exercise price of $10.56 per share. See Note 6 to Consolidated Financial Statements.

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SELECTED CONSOLIDATED FINANCIAL DATA

The following table contains certain selected consolidated financial data of the Company and is qualified in its entirety by the more detailed Consolidated Financial Statements included elsewhere in this Prospectus. The consolidated statements of operations data for the fiscal years ended March 31, 1995, 1996 and 1997, and the consolidated balance sheet data as of March 31, 1996 and 1997, have been derived from the Consolidated Financial Statements, which statements have been audited by Arthur Andersen LLP, independent public accountants, and are included elsewhere in this Prospectus. The consolidated statement of operations data for the fiscal years ended March 31, 1993 and 1994, and the consolidated balance sheet data as of March 31, 1993, 1994 and 1995 have been derived from the Company's consolidated financial statements, which statements have been audited by Arthur Andersen LLP and are not included in this Prospectus. The consolidated statement of operations data for the three months ended June 30, 1996 and 1997, and the consolidated balance sheet data as of June 30, 1997 have been derived from unaudited Consolidated Financial Statements included elsewhere in this Prospectus. These unaudited financial statements have been prepared on the same basis as the audited financial statements and, in the opinion of management, include all adjustments and reclassifications (consisting only of normal recurring adjustments and reclassifications) necessary to present fairly the financial condition and results of operations for the periods presented. The results for the quarter ended June 30, 1997 are not necessarily indicative of the results that may be expected for the full year. This data should be read in conjunction with the Consolidated Financial Statements and "Management's Discussion and Analysis of Financial Condition and Results of Operations" appearing elsewhere herein.

                                                                      THREE MONTHS
                                  YEAR ENDED MARCH 31,               ENDED JUNE 30,
                         ------------------------------------------- ---------------
                          1993     1994     1995     1996     1997    1996    1997
                         -------  -------  -------  -------  ------- ------- -------
                                  (in thousands, except per share data)
STATEMENT OF OPERATIONS
 DATA:
Revenues:
  Products.............. $ 1,709  $ 4,648  $ 6,893  $ 9,725  $12,311  $2,868  $4,207
  Contracts.............   1,736    2,027    2,337    3,118    4,151     817   1,829
                         -------  -------  -------  -------  ------- ------- -------
    Total revenues......   3,445    6,675    9,230   12,843   16,462   3,685   6,036
Costs and expenses:
  Cost of products......   2,042    2,211    3,289    3,921    5,361   1,049   1,529
  Research and
   development (1)......   2,097    2,431    2,464    3,218    3,833     864   1,643
  Selling, general and
   administrative.......   3,803    4,553    4,278    5,741    7,068   1,519   2,117
                         -------  -------  -------  -------  ------- ------- -------
    Total costs and
     expenses...........   7,942    9,195   10,031   12,880   16,262   3,432   5,289
                         -------  -------  -------  -------  ------- ------- -------
Income (loss) from
 operations.............  (4,497)  (2,520)    (801)     (37)     200     253     747
Interest and other
 income.................     604      537      449      528      535     130     124
                         -------  -------  -------  -------  ------- ------- -------
Net income (loss)....... $(3,893) $(1,983) $  (352) $   491  $   735 $   383 $   871
                         =======  =======  =======  =======  ======= ======= =======
Net income (loss) per
 common and common
 equivalent share....... $ (0.60) $ (0.31) $ (0.05) $  0.07  $  0.10 $  0.05 $  0.12
                         =======  =======  =======  =======  ======= ======= =======
Weighted average number
 of common and common
 equivalent shares
 outstanding............   6,441    6,461    6,512    6,995    7,162   7,206   7,567

                                        MARCH 31,                    JUNE 30, 1997
                         --------------------------------------- ---------------------
                          1993    1994    1995    1996    1997   ACTUAL  PRO FORMA (2)
                         ------- ------- ------- ------- ------- ------- -------------
                                             (in thousands)
BALANCE SHEET DATA:
Cash, cash equivalents
 and short-term
 marketable securities.. $ 9,486 $ 3,067 $ 4,491 $10,647 $ 9,361 $ 8,766    $24,904
Working capital.........  10,727   6,043   6,304  12,735  12,850  13,291     29,301
Long-term investments...   4,307   7,219   6,533     --      --      --         --
Total assets............  17,504  15,426  14,730  16,209  18,547  19,715     35,852
Long-term debt..........   3,820   3,773     --      --      --      --         --
Total stockholders'
 investment (3).........  12,460  10,589  13,305  13,945  15,225  16,162     32,172


(1) Research and development expenses include certain contract costs. See Note 1(e) to Consolidated Financial Statements.
(2) Gives effect to the receipt of net proceeds of approximately $16.0 million from the sale of 1,242,710 shares of Common Stock by the Company in July 1997. See "Certain Transactions" and Note 10 to Consolidated Financial Statements.
(3) No dividends on Common Stock were declared or paid during any of the periods presented.

19

MANAGEMENT'S DISCUSSION AND ANALYSIS OFFINANCIAL CONDITION AND RESULTS OF
OPERATIONS

The following Management's Discussion and Analysis of Financial Condition and Results of Operations contains forward-looking statements which involve risks and uncertainties. The Company's actual results could differ materially from those anticipated in these forward-looking statements as a result of certain factors, including those set forth under "Risk Factors" and elsewhere in this Prospectus.

OVERVIEW

The Company is a leader in the research and development of cardiac assist and heart replacement technology. The Company developed, manufactures and sells the BVS, a temporary cardiac assist device, and is developing a totally implantable artificial heart. The Company's operating results reflect the dual activities of commercial operations and investments in the research and development of new technologies.

The BVS is a temporary cardiac assist device designed to provide a patient's failing heart with full circulatory assistance while allowing the heart to rest, heal and recover its function. The BVS is the only device that can provide full circulatory assistance approved by the FDA as a bridge-to- recovery device for the treatment of patients with reversible heart failure. Since fiscal 1994, the first full year of marketing the BVS in the United States, increasing new orders and reorders of the BVS have made product revenues the largest contributor to the Company's revenues. The Company has focused its initial selling efforts of the BVS on the approximately 300 medical centers that perform the most heart surgery procedures, teaching centers and transplant centers. As of September 29, 1997, the BVS had been purchased by over 275 medical centers in the United States, many of which are within the group of medical centers initially targeted. The BVS is comprised of a pneumatic drive and control console, single-use external blood pumps and cannulae. During the three months ended June 30, 1997 and fiscal 1997, revenues from BVS sales represented greater than 90% of the Company's total product revenues with no single customer representing more than 5% of product revenues.

Research and development is a significant portion of the Company's operations. The Company's research and development efforts are focused on the development of new products, primarily related to cardiac assist and heart replacement, and the continued enhancement of the BVS and related technologies. The Company's research and development expenses have been primarily attributable to research and development under the Company's government contracts and grants. Revenues from contract research and development and total research and development costs have increased in each of the past three years. The Company's government-sponsored research and development contracts generally provide for payment on a cost-plus-fixed-fee basis. The Company accounts for revenue under these contracts and grants as work is performed, provided that the government has appropriated sufficient funds for the work. There can be no assurance that the government will not terminate, reduce or delay the funding for any of the Company's contracts. In addition, there can be no assurance that the Company will be successful in obtaining any new government contracts or further extensions to existing contracts.

The Company plans to use its own resources to fund the further development of the TAH in amounts significantly in excess of the funding provided under the Company's TAH Contract. The Company estimates that the development of the TAH, including conducting pre-clinical and clinical studies and obtaining regulatory approvals, will require substantial funds. There can be no assurance that the Company will be able to develop the TAH, or receive the required regulatory approvals to commence clinical trials on a timely basis or within budget, if at all.

The Company has significant net tax operating loss carryforwards and tax credit carryforwards. As a result, income tax expense incurred during the periods presented have not been material. See Note 4 to Consolidated Financial Statements.

20

RESULTS OF OPERATIONS

The following table sets forth certain consolidated statements of operations data for the periods indicated as a percentage of total revenues:

                                                      THREE MONTHS
                                                          ENDED
                             YEAR ENDED MARCH 31,       JUNE 30,
                             -----------------------  --------------
                              1995     1996    1997    1996    1997
                             ------   ------  ------  ------  ------
Revenues:
  Products..................   74.7%    75.7%   74.8%   77.8%   69.7%
  Contracts.................   25.3     24.3    25.2    22.2    30.3
                             ------   ------  ------  ------  ------
    Total revenues..........  100.0    100.0   100.0   100.0   100.0
Costs and expenses:
  Cost of products..........   35.6     30.5    32.6    28.5    25.3
  Research and development..   26.7     25.1    23.3    23.4    27.2
  Selling, general and
   administrative...........   46.4     44.7    42.9    41.2    35.1
                             ------   ------  ------  ------  ------
    Total costs and
     expenses...............  108.7    100.3    98.8    93.1    87.6
                             ------   ------  ------  ------  ------
Income (loss) from
 operations.................   (8.7)    (0.3)    1.2     6.9    12.4
Interest and other income...    4.9      4.1     3.2     3.5     2.0
                             ------   ------  ------  ------  ------
Net income (loss)...........   (3.8)%    3.8%    4.4%   10.4%   14.4%
                             ======   ======  ======  ======  ======

Three Months Ended June 30, 1997 and 1996

Revenues. Total revenues, excluding interest income, increased by 64% in the three months ended June 30, 1997 to $6.0 million compared to $3.7 million in the three months ended June 30, 1996. This increase was attributable to an increase in both product and contract revenues.

Product revenues increased by 47% in the three months ended June 30, 1997 to $4.2 million compared to product revenues of $2.9 million in the three months ended June 30, 1996. This increase was primarily attributable to increased unit sales of BVS blood pumps and consoles.

Contract revenues increased by 124% in the three months ended June 30, 1997 to $1.8 million from $820,000 in the three months ended June 30, 1996. This increase primarily reflects increased activity under the Company's TAH Contract. The Company accounts for revenue under its government contracts and grants as work is performed, provided that the government has appropriated sufficient funds for the work. Through June 30, 1997, the government has appropriated $4.9 million of the $8.5 million of its Phase II TAH Contract amount. The original government appropriation schedule calls for no further appropriations for the TAH Contract until October 1998. This schedule is subject to change at the discretion of the government. During the three months ended June 30, 1997, the Company recognized $1.7 million of revenue under its TAH Contract, reflecting the highest quarterly spending by the Company on the TAH. As a result of this increased activity through June 30, 1997, the Company has recognized $3.4 million of the $4.9 million appropriated as revenue. The Company anticipates that its rate of spending on TAH development will further increase and that this spending will exceed the remaining currently appropriated balance before September 30, 1997, at which time the Company intends to fund TAH development without offsetting contract revenue or reimbursement from the government. The Company believes that certain of these excess costs may be reimbursable under the TAH Contract, if and when additional appropriation under the TAH Contract is made. Due to its accelerated TAH development activity and the timing of government appropriations, the Company believes that it will experience significant quarterly fluctuations in contract revenues. The Company also believes that the Company's total expenses to complete the development of the TAH will significantly exceed the remaining TAH Contract amount.

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Cost of Products. Cost of products sold as a percentage of product sales decreased to 36.3% in the three months ended June 30, 1997 as compared to 36.6% in the three months ended June 30, 1996. This decrease primarily reflects increased operational efficiencies.

Research and Development Expenses. Research and development expenses increased by 90% to $1.6 million, 27.2% of total revenues, in the three months ended June 30, 1997 from $860,000, 23.4% of total revenues, in the three months ended June 30, 1996. This increase primarily reflected a higher level of activity under the Company's research and development contracts and grants, particularly the TAH Contract. The Company anticipates that research and development expenses will increase significantly as a result of its plans to increase its internally funded research and development efforts for the TAH.

Selling, General and Administrative Expenses. Selling, general and administrative expenses increased by 39% to $2.1 million, 35.1% of total revenues, in the three months ended June 30, 1997 from $1.5 million, 41.2% of total revenues, for the three months ended June 30, 1996. This increase primarily reflected increased sales and marketing expenses, particularly increased personnel and sales commissions, related to the increase in product revenues. The decrease in selling, general and administrative expenses as a percentage of total revenues reflects the Company's higher revenue base to support these increased costs.

Interest and Other Income. Interest and other income consists primarily of interest income on the Company's investment balances, net of interest and other expenses. In each of the three month periods ended June 30, 1997 and June 30, 1996, interest and other income remained virtually unchanged at approximately $120,000.

Fiscal Years Ended March 31, 1997, 1996 and 1995

Revenues. Total revenues, excluding interest income, for fiscal 1997 increased to $16.5 million as compared to $12.8 million in fiscal 1996 and $9.2 million in fiscal 1995, representing increases of 28% and 39% in fiscal 1997 and 1996, respectively.

Product revenues increased to $12.3 million in fiscal 1997 from $9.7 million in fiscal 1996, and $6.9 million in fiscal 1995, representing increases of 27% and 41% in fiscal 1997 and fiscal 1996, respectively. These increases were primarily attributable to growing United States unit sales of the BVS consoles and single-use products, including increased blood pump reorders, and to increased average selling prices of BVS consoles and single-use products. The majority of the Company's product revenues in the last three years have been to United States customers. International revenues represented 7%, 9% and 13% of total product revenues in fiscal 1997, 1996 and 1995 respectively. The Company's product revenues from its dental business, ABIODENT, increased in fiscal 1997 but were less than 10% of total product revenues.

Contract revenues increased to $4.2 million in fiscal 1997 from $3.1 million in fiscal 1996 and $2.3 million in fiscal 1995, representing increases of 33% in both fiscal 1997 and 1996. These increases are reflective of the increased level of the Company's research and development activities under its government cost reimbursement contracts in each year. The majority of the Company's contract revenues, approximately 59% in fiscal 1997, were recognized in connection with the research and development under the TAH Contract, including amounts paid under Phase I of that contract.

Cost of Products. Cost of products represented approximately 44%, 40% and 48% of product revenues for fiscal 1997, 1996 and 1995, respectively. The decrease in gross product margins experienced in fiscal 1997 as compared to fiscal 1996 is primarily attributable to the mix of products sold. The Company generally receives higher margins on the sale of single-use blood pumps than on the sale of consoles. A higher proportion of the Company's revenues was derived from the sale of BVS consoles in fiscal 1997 as compared to fiscal 1996. In addition, the Company's margins in fiscal 1997 were affected by increased costs of production of the single-use blood pumps, including approximately $200,000 in costs related to the Company's voluntary recall during the third quarter of fiscal 1997 of certain production lots of single- use BVS blood pumps. During

22

that quarter, the Company became aware of certain isolated cases where components of its BVS blood pumps exhibited certain abnormalities. In response, the Company issued a product recall for and removed from inventory all blood pumps from the affected production lots.

Research and Development Expenses. Cost of research and development increased to approximately $3.8 million, 23.3% of total revenues, in fiscal 1997 compared to $3.2 million, 25.1% of total revenues, and $2.5 million, 26.7% of total revenues, in fiscal 1996 and 1995, respectively. These increases reflect increased activity under research and development contracts and grants, which are billed on a cost-plus-fixed-fee basis. Costs of internal research and development primarily relate to continued engineering support and improvement of existing products as well as regulatory support for all products.

Selling, General and Administrative Expenses. Selling, general and administrative expenses increased to $7.1 million, 42.9% of total revenues, in fiscal 1997 from $5.7 million, 44.7% of total revenues, and $4.3 million, 46.4% of total revenues, in fiscal 1996 and fiscal 1995, respectively. These increases primarily reflect increased costs associated with higher product revenues, including the expansion of the United States based sales team and clinical post-sales support personnel. The decreases in selling, general and administrative expenses as a percentage of total revenues in fiscal 1996 and 1997 primarily reflect the Company's higher revenue base to support these increased costs.

Interest and Other Income. Interest and other income totaled $540,000, $530,000, and $450,000, for fiscal 1997, 1996 and 1995, respectively. This income primarily represents income earned on short-term investments.

LIQUIDITY AND CAPITAL RESOURCES

As of June 30, 1997, the Company had $8.8 million of cash and short-term marketable securities, a decrease of $600,000 from March 31, 1997. On a pro forma basis, after giving effect to the receipt of net proceeds of $16.0 million from the sale of 1,242,000 shares of Common Stock by the Company in July 1997, the Company had $24.9 million of cash and short-term marketable securities. The Company also has a $3,000,000 line of credit from a bank which expires in September 1998, and which was entirely available at June 30, 1997.

In the three months ended June 30, 1997, operating activities used net cash of $10,000. Net sources of cash provided by operating activities during the three months ended June 30, 1997 reflected net income of approximately $870,000, including depreciation and amortization expenses of $150,000, and an increase in accrued expenses of approximately $300,000. These sources of cash were offset by an increase in accounts receivable of approximately $1.0 million, a decrease in accounts payable of approximately $70,000 and increases in prepaid expenses and inventory of $30,000 and $190,000 respectively.

During the three months ended June 30, 1997, investing activities used $60,000 of cash. Net cash used in investing activities included approximately $650,000 of purchases and improvements of property and equipment, primarily related to the purchase of equipment to support its TAH development and to support its increase in personnel. This use of cash was partially offset by cash received as a result of approximately $580,000 of net maturities of short-term marketable securities. Although the Company does not currently have significant capital commitments, the Company believes that it will continue to make significant investments over the next several years to support the development and commercialization of its products and the expansion of its manufacturing facility.

The Company believes that its revenues and existing resources, together with the proceeds from the offering, will be sufficient to fund its planned operations, including the planned increase in its internally funded TAH development efforts, for at least through the next twelve months.

23

BUSINESS

The Company is a leader in the research and development of cardiac assist and heart replacement technology. The Company developed, manufactures and sells the BVS, a temporary cardiac assist device designed to provide a patient's failing heart with full circulatory assistance while allowing the heart to rest, heal and recover its function. The BVS is most frequently used in patients whose hearts fail to immediately recover function following heart surgery. The BVS is the only device that can provide full circulatory assistance approved by the FDA as a bridge-to-recovery device for the treatment of patients with reversible heart failure.

The Company is developing a battery-powered totally implantable artificial heart intended as a permanent replacement device to assume the full pumping function of both the left and right ventricles of the heart. The TAH is designed for use by patients with irreparably damaged hearts and at risk of death due to acute myocardial infarction ("AMI"), chronic ischemic disease or some form of end-stage congestive heart failure, but whose vital organs otherwise remain viable.

HEART DISEASE

Overview

The human heart consists of four chambers, including a left and right ventricle. The left ventricle pumps oxygen rich blood throughout the body. The right ventricle pumps oxygen depleted blood which has been circulated through the body to the lungs where it is re-oxygenated. The heart muscles of the ventricles require an uninterrupted supply of oxygenated blood, which is provided through coronary arteries.

Insufficient blood flow to the muscles of the heart, known as ischemia, results in oxygen deprivation and leads to various complications. These complications include reduced cell function and, in more severe cases, permanent damage to the heart muscle, such as AMI. Diseases to the coronary arteries which affect blood flow to the heart are generally classified as coronary heart disease.

Congestive heart failure is a condition manifested clinically by an enlarged heart. Congestive heart failure develops over time primarily due to excess demand on the heart muscle caused by a variety of factors, including chronic hypertension (high blood pressure), incompetent valves, coronary heart disease, infections of the heart muscle or the valves and congenital heart problems.

Abnormalities in the electrical conduction system regulating the pumping function of the heart, known as rhythm disorders, can also lead to complications. These complications range from ventricular fibrillation (unsynchronized contractions) and arrhythmia (irregular heartbeats) to cardiac arrest. Most cardiac arrests result in sudden death.

Prevalence and Mortality

In 1994, there were an estimated 13.7 million people with coronary heart disease, 4.8 million people with congestive heart failure, 4.0 million people with rhythm disorders, and 1.4 million people with valvular diseases in the United States. These diseases and conditions resulted in approximately 750,000 deaths in 1995, of which approximately half were sudden deaths. Of the deaths that did not occur suddenly, approximately 110,000, 131,000, and 59,000 were associated with AMI, chronic ischemic disease and congestive heart failure, respectively.

Circulatory Support Therapies

In general, there are four modalities for the treatment or support of failing ventricles: pharmaceutical therapies, cardiological interventions, surgical corrections, and mechanical cardiac interventions. Pharmaceutical therapies, including diuretics, ACE inhibitors, beta blockers and calcium channel blockers, are commonly the first treatment option. Cardiological interventions, including angioplasty and the use of stents, are minimally invasive procedures that primarily address certain forms of coronary heart disease. Surgical corrections, including coronary bypass surgery and valve replacement, while effective, are a viable alternative only for those patients with enough functional heart muscle to sustain life. Mechanical cardiac

24

interventions involve the use of devices for those patients whose heart muscles are unable to sustain life without cardiac assistance.

Mechanical Cardiac Interventions

Mechanical cardiac interventions can be divided into three groups of devices: temporary cardiac assist, permanent cardiac assist and heart replacement.

Temporary Cardiac Assist. Patients who are candidates for temporary cardiac assist consist of those with severely but reversibly failing hearts and those who need ventricular support to remain alive while they await transplantation. Temporary cardiac devices which are designed to support the recovery of patients with reversibly failing hearts are referred to as "bridge-to- recovery" devices, and those which can support patients awaiting transplantation are referred to as "bridge-to-transplant" devices. Approximately 12,000 patients with potentially recoverable hearts die every year in the United States following heart surgery. Bridge-to-recovery devices can save the lives of many of these patients by temporarily assuming the pumping function of the heart, while allowing the heart to rest, heal and recover its normal function. These devices can also be used for bridge-to- recovery for nonsurgical patients who would otherwise die as a result of certain transient viral infections that attack the heart muscle. Bridge-to- transplant devices are ventricular assist devices ("VADs") used to support a portion of the patients awaiting heart transplants. There are approximately 2,300 heart transplants performed in the United States annually.

Permanent Cardiac Assist. Patients with life-impairing or life-threatening heart failure due to permanent muscle damage may require support to either the left or both ventricles. Depending upon the severity of the damage and the nature of the heart's condition, these patients may be helped with permanent assist devices. Permanent assist devices under development can be grouped into two types, those that pump blood directly, such as VADs, and those that wrap around and help contract the heart without direct blood contact. Both types potentially may be used to treat end-stage congestive heart failure patients as well as those patients who are not at imminent risk of death but whose daily activities are generally restricted due to their weakened hearts. In 1995, there were approximately 59,000 deaths in the United States attributable to congestive heart failure.

Heart Replacement. Patients with irreparably damaged hearts and at risk of death due to AMI, chronic ischemic disease or some form of end-stage congestive heart failure but whose vital organs otherwise remain viable are candidates for heart replacement. Included among these patients are those with massive heart damage or infection, severe rhythm disorders, prosthetic valves, clots or thrombi in the ventricles, high pulmonary resistance, chronic right ventricle failure and heart transplant rejection. Among these combined groups, the Company believes that approximately 60,000 patients per year could benefit from a heart replacement device. No life-supporting treatment is currently available for these patients except for the approximately 2,300 who receive heart transplants annually in the United States. Currently, available donor hearts are primarily reserved for transplantation of select end-stage congestive heart failure patients because many of these patients are able to survive for the long waiting periods required before a suitably matched donor heart can be found. The Company believes that the development of an artificial heart would increase the number of lives saved by eliminating the scarcity of, and waiting period for, available hearts.

ABIOMED PRODUCTS AND PRODUCTS UNDER DEVELOPMENT

The Company markets the BVS, which is a temporary cardiac assist device, and is developing the TAH and the Heart Booster, which are replacement and permanent cardiac assist devices, respectively.

The BVS-5000 Bi-Ventricular Assist System. The BVS is a temporary cardiac assist device designed to provide a patient's failing heart with full circulatory assistance while allowing the heart to rest, heal and recover its function. The BVS is most frequently used in patients whose hearts fail to immediately recover function following heart surgery. In November 1992, the Company received PMA approval from the FDA for

25

the BVS for this post-surgery therapy. In 1996 and 1997, the FDA approved the use of the BVS for additional indications, expanding its use for the treatment of all patients with reversible heart failure as a bridge-to-recovery device. The BVS is the only device that can provide full circulatory assistance approved by the FDA for the treatment of these patients.

The BVS system is comprised of a microprocessor-based pneumatic drive and control console, single-use external blood pumps and cannulae. The BVS console incorporates a closed-loop control system that automatically adjusts the pumping rate, similar to the natural heart. The dual-chamber blood pumps provide complete or partial pumping of blood for the left, right or both sides of a patient's heart and are designed to mimic the function of the natural heart. The BVS blood pumps reduce the risk of damaging blood cells by filling the ventricles passively and continuously by gravity rather than by suction. The cannulae are specially designed tubes used to connect the blood pumps to the heart. The integration of the cannulae, blood pumps and console creates a system with the ability to reduce the load on the heart, provide pulsatile blood flow to vital organs and allow the heart muscles time to rest and recover. Stabilization of patients who recover under BVS support typically occurs in a period of less than one week. The BVS is designed to be simple and easy to use and does not require a specially trained technician to constantly monitor or adjust the pumping parameters, which can reduce hospital operating costs.

The following diagram illustrates the BVS.

[SCHEMATIC OF PATIENT LYING ON BED IN BVS SUPPORT. COMPONENTS OF THE BVS ARE IDENTIFIED WITH CAPTIONS.]

26

The BVS is intended for use in any hospital performing open-chest cardiac surgery, of which there are more than 900 in the United States. As of September 29, 1997, the BVS had been purchased by over 275 medical centers in the United States including many of the largest centers. Typically, medical centers initially purchase the BVS console, two to four BVS single-use blood pumps, cannulae, training and related accessories. The BVS is capable of supporting the left, right or both ventricles of the heart. In the Company's clinical experience, approximately half of the patients required support to both ventricles of the heart, and therefore the use of two single-use BVS blood pumps. The Company's United States list price for a BVS console, and a blood pump and cannulae set are $59,500 and $6,950, respectively.

The Totally Implantable Artificial Heart (TAH). The Company is developing a battery-powered totally implantable artificial heart intended as a permanent replacement device to assume the full pumping function of both the left and right ventricles of the heart. The TAH is designed for use by patients with irreparably damaged hearts and at risk of death due to AMI, chronic ischemic disease or some form of end-stage congestive heart failure but whose vital organs otherwise remain viable. Included among these patients are those with massive heart damage or infection, severe rhythm disorders, prosthetic valves, clots or thrombi in the ventricles, high pulmonary resistance, chronic right ventricle failure and heart transplant rejection.

The core technology for the TAH has been under development by the Company since the Company's inception. The Company has completed its feasibility studies of the TAH system and substantially finalized the design of the TAH. The system and individual components have been tested through a variety of laboratory and animal tests. The Company is currently accelerating the development of the TAH and is devoting significant resources towards improving the manufacturing process in order to reach consistency and reliability levels necessary to conduct advanced pre-clinical and clinical trials. The Company's goal is to initiate clinical trials of the TAH by the end of the year 2000. There can be no assurance that the Company will be able to successfully complete pre-clinical testing of the TAH and receive FDA approval to begin clinical trials of the TAH in a timely manner, if at all. Moreover, pre- clinical trials may not be predictive of results that will be obtained in clinical trials. The Company is consulting with regulatory authorities, leading medical centers and physicians to define protocols and patient populations for future clinical trials. The Company has built a new development and pilot-scale manufacturing facility, and has significantly increased the personnel focused on the manufacturability and testing of the TAH.

The TAH system is comprised of a thoracic unit, or "replacement heart," a rechargeable battery, a miniaturized electronics package, a transcutaneous energy transmission system, and an external belt-worn battery pack. The thoracic unit includes two artificial ventricles with their associated valves and a hydraulic pumping system. The unit provides complete pumping of the blood to the lungs and throughout the body. The ventricles and their associated valves are being designed and manufactured with seamless surfaces which reduce the risk of damaging blood cells, or creating clots or thrombi. The electronics package automatically adjusts the rate and amount of blood flow to the patient's needs, similar to the natural heart. The implantable rechargeable battery and the transcutaneous energy transmission system eliminate the need for wires penetrating the patient's skin and associated risks of infection. The entire TAH system is being designed to be highly reliable with minimal maintenance and patient involvement.

27

The following diagram illustrates the TAH.

[SCHEMATIC OF UPPER TORSO OF PATIENT WITH A TAH IMPLANTED. COMPONENTS OF THE TAH ARE IDENTIFIED WITH CAPTIONS.]

Much of the development of the TAH has been funded by the NHLBI. Prior to receiving its most recent $8.5 million TAH Contract extension, the Company demonstrated to the NHLBI that the basic design of the system functioned in laboratory and animal models without significant complications. The Company retains the right to market the resulting TAH without royalty to NHLBI. The Company is responsible for the complete research and development program and has collaborated over the past nine years with the Texas Heart Institute for pre-clinical product testing and evaluation.

The Heart Booster. The Company is developing the Heart Booster as a permanent cardiac assist device designed to wrap around and help contract the heart without direct blood contact. The Heart Booster is being designed for use in patients with congestive heart failure who are not at imminent risk of death, but whose daily activities are generally restricted due to their weakened hearts. This device, unlike most devices being developed to pump blood directly, avoids the potential risks of damage to blood cells and formation of clots and thrombi. The Heart Booster consists of a pliant and thin artificial plastic "muscle" that can be wrapped around the heart. This artificial muscle is being developed to mimic the contraction-relaxation characteristics of the heart muscle and provide sufficient contractility. The design goal of the Heart Booster is to restore an acceptable and active quality of life to the patient. The Heart Booster is in an earlier stage of research and development than the TAH and is being developed under a five year, $4.3 million contract from the NHLBI. Columbia Presbyterian Medical Center is collaborating with the Company on this project for pre-clinical testing and evaluation. There can be no assurance that the Company will be successful in developing the Heart Booster.

28

ABIOMED STRATEGY

The Company's goal is to be a leader in the development, manufacture and marketing of mechanical cardiac assist and replacement devices that address the varying needs of a wide range of patients.The Company is pursuing the following strategies to achieve this objective.

Accelerate Development of the TAH. The Company is devoting significant resources with the goal to be the first to clinically introduce a totally implantable artificial heart. The Company is consulting with regulatory authorities, leading medical centers and physicians to define protocols and patient populations for future clinical trials. The Company has built a new development and pilot-scale manufacturing facility, and has significantly increased the personnel focused on the manufacturability and testing of the TAH.

Increase Market Penetration of BVS. The Company has recently increased the size of both its domestic sales force and its clinical support group. Its sales force focuses on BVS sales to new customers, while its clinical support group focuses on training and educating existing customers in order to improve clinical outcomes and increase BVS blood pump usage. As of September 29, 1997, the BVS had been purchased by over 275 medical centers in the United States, including many of the largest centers. The Company believes that its relationships with its customers will facilitate the adoption of the BVS by other medical centers.

Maintain and Enhance Technological Leadership. The Company is a leader in the research and development of mechanical cardiac assist and replacement devices. The Company has accumulated substantial proprietary knowledge and has been granted a number of patents relating to the technologies incorporated in these devices. The Company intends to continue to enhance and expand upon its core technical expertise to maintain its leadership and to further develop advanced mechanical cardiac assist and replacement devices.

Pursue Strategic Relationships to Support Research and Commercialization Efforts. Many of the Company's products under development, including the TAH, have been funded using government contracts and grants. The Company seeks funding from third parties to support its research and development programs and generally limits the use of its own funds until the scientific risk is reduced. In addition, the Company intends to pursue collaborative relationships to develop and commercialize the Company's non-cardiac assist technologies.

MARKETING AND SALES

Approximately 900 medical centers in the United States perform heart surgery. The Company has focused its initial BVS selling efforts on teaching and transplant centers as well as the medical centers that perform the most heart surgery procedures. As of September 29, 1997, the BVS had been purchased by over 275 medical centers in the United States, many of which are within the group of medical centers initially targeted. The Company believes that its installed base of customers provides an opportunity for reorders of the single-use BVS blood pumps as well as a reference base to assist in selling to new accounts.

The Company sells the BVS in the United States through direct sales and clinical support teams. As of September 29, 1997, the Company's BVS sales, clinical support, marketing and field service teams included 35 full-time employees. Its sales force focuses on BVS sales to new customers. Its clinical support group focuses on training and educating existing customers in order to improve clinical outcomes and increase BVS blood pump usage. The Company believes the efforts of its clinical support group contribute significantly to increasing the number of lives saved by the BVS and increasing usage and reorders of BVS blood pumps. The Company also believes that its sales and support teams will be key assets for the introduction of potential future products such as the TAH. Building on its experience in the United States, the Company also is working to expand its international sales efforts both through distributors, including a recent collaborative arrangement for distribution in Japan, and by selling directly in select European markets. The Company believes that sales of its BVS may be somewhat seasonal, with reduced sales in the summer months, reflecting hospital personnel and physician vacation schedules.

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MANUFACTURING

The Company manufactures the BVS console, BVS blood pumps and related accessories. The manufacture of BVS consoles consists primarily of assembly, testing and quality control. The Company purchases the majority of the materials, parts and peripheral components used in the BVS consoles. The Company manufactures certain blood contacting components for the BVS blood pumps, including valves and bladders, from its proprietary Angioflex polymer.

The nature of the Company's products requires high quality manufacturing. The Company's manufacturing and quality testing processes and procedures are highly dependent on the diligence and experience of the Company's personnel. To the extent that the Company's manufacturing volumes expand or the Company begins the manufacture of new products, this dependence on personnel will likely increase. In addition, the manufacture of blood contacting surfaces of the Company's products requires a high degree of precision. These surfaces are manufactured from polyurethane-based materials. The quality and composition of polyurethane-based products can vary significantly based on numerous factors including humidity, temperature, material content and air flow during the manufacturing process. The Company's products also incorporate plastic components for non-blood contacting surfaces. The Company relies on third- party vendors to provide these components to the Company's specifications. The Company is not able to fully inspect the quality of all vendor supplied components and, therefore, relies on its vendors with respect to the quality of these components. Once the plastic-based components of the Company's products have been assembled, accessibility for inspection is limited. If a defect is detected in as few as one of the Company's products, or in one component of a Company product, it can result in the recall or restriction on sale of products. Once assembled, in most cases, the Company's blood contacting components cannot be reworked for human use. The manufacturing lead times for parts and assemblies, particularly the polyurethane-based components, can take many weeks from the date that all materials and components are received by the Company. In addition, vendor lead times for materials and components of the Company's products vary significantly, with lead times for certain materials and components exceeding six months.

The Company is planning to expand its manufacturing facility for the BVS during the next twelve months. There can be no assurance that the products manufactured in the expanded facility will be manufactured at the same cost and quality as the BVS is currently being manufactured. In addition, to the extent that the Company's products under development have been manufactured, they have been manufactured as prototypes with, at most, pilot-scale production. The Company's products under development are likely to involve additional manufacturing complexities and high quality requirements. There can be no assurance that the Company will be able to increase production of the BVS or manufacture future products, if developed and approved, in commercial quantities on a consistent and timely basis, with acceptable cost and quality. The inability to manufacture current and future products in sufficient quantities in a timely manner, and with acceptable cost and quality, would have a material adverse effect on the Company's business, financial condition and results of operations.

The Company relies on outside vendors to supply certain components used in the BVS and in its products under development. Certain of the components of the BVS are supplied by sole source vendors or are custom made for the Company. From time to time, suppliers of certain components of the BVS have indicated that they intend to discontinue, or have discontinued, making such components. In addition, certain of these components are supplied from single sources due to quality considerations, costs or constraints imposed by regulatory authorities. There are relatively few additional sources of supply for such components and establishing additional or replacement suppliers for such components cannot be accomplished quickly and may require FDA approval. In the past, certain suppliers have announced that, due to government regulation or in an effort to reduce potential product liability exposure, they intend to limit or terminate sales of certain products to the medical industry. There can be no assurance that, if such an interruption were to occur, the Company would be able to find suitable alternative supplies at reasonable prices or would be able to obtain requisite regulatory approvals in a timely manner, if at all. Similarly, when and if the Company reaches the clinical testing stage of its products under development, it may find that certain components become more

30

difficult to source from outside vendors due to the product liability risk perceived by those vendors. The Company's inability to obtain acceptable components in a timely manner or to find suitable replacements at an acceptable cost would have a material adverse effect on the Company's business, financial condition and results of operations.

RESEARCH AND PRODUCT DEVELOPMENT

The Company has substantial expertise in electro-mechanical systems, cardiac physiology and experimental surgery, blood-material interactions, fluid mechanics and hemodynamics, internal and external electronic hardware, software, plastics processing, lasers and optical physics. The Company's research and development efforts are focused on the development of new products, primarily related to mechanical cardiac assist and heart replacement, and the continued enhancement of the BVS and related technologies. The Company's research and development personnel also are involved in establishing protocols, monitoring and submitting test data to the FDA and corresponding foreign regulatory agencies to obtain the necessary clearances and approvals for its products. Sophisticated tools, such as 3- dimensional CAD/CAM, and procedures are used in an effort to ensure smooth transition of new products from research to product development to manufacturing.

Cardiac assist products currently under development by the Company include the TAH, the Heart Booster, and a variety of specialized pumps, such as a miniaturized rotary blood pump and a magnetically-suspended centrifugal pump. The Company is also developing devices in the area of minimally invasive surgery applications, such as tissue welding and vascular welding for the repair of small arteries.

During the three months ended June 30, 1997 and the fiscal years ended March 31, 1997, 1996 and 1995, the Company expended $1.6 million, $3.8 million, $3.2 million and $2.5 million, respectively, on research and development. A substantial portion of these expenses were funded by government contracts and grants. See "Management's Discussion and Analysis of Financial Condition and Results of Operations" and "Business--Strategic Relationships."

STRATEGIC RELATIONSHIPS

Genzyme

In July 1997, the Company sold 1,153,846 shares of Common Stock to Genzyme Corporation ("Genzyme"). In connection with this sale, the Company and Genzyme agreed to discuss collaborative arrangements that would allow them to jointly develop and commercialize products which combine biotechnology and biomedical engineering, primarily for the surgical market. A potential target for collaboration is minimally invasive cardiac surgery, an emerging field in which surgeons use new products and techniques to reduce the trauma, recovery period, and expense of heart surgery. The Company and Genzyme are engaged in ongoing discussions regarding this potential collaboration. The Chief Executive Officer of Genzyme is a member of the Company's board of directors. There can be no assurance that the Company and Genzyme will agree to jointly collaborate on any project, that any such project would result in the development of any product, or that any such product, if developed, would be commercially successful. See "Certain Transactions."

National Heart, Lung and Blood Institute

Since the Company's inception, United States government agencies, particularly the NHLBI, have provided significant support to the Company's product development efforts. The most significant current funding from the NHLBI supports the Company's development of the TAH and Heart Booster. In September 1996, the Company received an $8.5 million extension to its TAH Contract from the NHLBI. In September 1995, the Company received a $4.3 million contract from the NHLBI to develop the Heart Booster. During the three months ended June 30, 1997 and the fiscal years ended March 31, 1997, 1996 and 1995, the

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Company recognized revenues of $1.8 million, $4.2 million, $3.1 million and $2.3 million, respectively, under United States government contracts and grants. All of the Company's government contracts and grants contain provisions making them terminable at the convenience of the government and are subject to government appropriations. There can be no assurance that the government will not terminate, reduce or delay the funding for any of the Company's contracts. In addition, there can be no assurance that the Company will be successful in obtaining any new government contracts or further extensions to existing contracts.

COMPETITION

Competition in the cardiac assist market is intense and subject to rapid technological change and evolving industry requirements and standards. Many of the companies developing or marketing cardiac assist products have substantially greater financial, product development, sales and marketing resources and experience than the Company. These competitors may develop superior products or products of similar quality at the same or lower prices. Moreover, there can be no assurance that improvements in current or new technologies will not make them technically equivalent or superior to the Company's products in addition to providing cost or other advantages. Other advances in medical technology, biotechnology and pharmaceuticals may reduce the size of the potential markets for the Company's products or render those products obsolete.

The BVS is the only device that can provide full circulatory assistance approved by the FDA as a bridge-to-recovery device for the treatment of patients with reversible heart failure. However, the Company is aware of at least one other company, Thoratec Laboratories Corporation, seeking approval of a temporary cardiac assist device to address this market. Approval by the FDA of products that compete directly with the BVS would increase competitive pricing and other pressures and could have a material adverse effect on the Company's business, financial condition and results of operations. The Company believes that it would compete with any such product on the basis of cost, clinical outcome and customer relations. There can be no assurance that the Company would be able to compete effectively with respect to these factors.

The Company is aware of other artificial heart development efforts in the United States, Canada, Europe and Japan. A team comprised of Pennsylvania State University and 3M Corporation, Inc. has been developing a heart replacement device for many years with significant NHLBI support. There are a number of companies, including Thermo Cardiosystems, Inc. and Novacor, a division of Baxter International, Inc., which are developing permanent cardiac assist products, including implantable left ventricular assist devices and miniaturized rotary ventricular assist devices, that may address markets that overlap with certain segments of the markets targeted by the Company's TAH. The Company's TAH may compete with those VADs for some patient groups, notably patients with severe congestive heart failure due to predominant left ventricle dysfunction. An implantable VAD supplements the pumping ability of a failing ventricle. In contrast, the TAH is being designed to replace failing ventricles. The Company believes that Thermo Cardiosystems, Inc. has commenced clinical testing for PMA approval of LVADs for permanent cardiac assist. The Company believes that the TAH, LVADs and other VADs, if developed, will generally be used to address the needs of different patient populations, with an overlap for certain segments of the heart failure population. There can be no assurance that the Company will develop and receive FDA approval to market its TAH on a timely basis, if at all, or that once developed, the TAH will be commercially successful.

The Company's customers frequently have limited budgets. As a result, the Company's products compete against the broad range of medical devices for these limited funds. The Company's success will depend in large part upon its ability to enhance its existing products and to develop new products to meet regulatory and customer requirements and to achieve market acceptance. The Company believes that important competitive factors with respect to the development and commercialization of its products include the relative speed with which it can develop products, establish clinical utility, complete clinical testing and regulatory approval processes, obtain reimbursement and supply commercial quantities of the product to the market. There can be no assurance that the Company will be able to compete successfully or that competition will not have a material adverse effect on the Company's business, financial condition and results of operations.

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THIRD-PARTY REIMBURSEMENT

The Company's BVS product is, and most of its products under development are intended to be, sold to medical institutions. Medical institutions and their physicians typically seek reimbursement for the use of these products from third-party payors, including Medicare, Medicaid, private health insurers and managed care organizations. As a result, market acceptance of the Company's current and proposed products may depend in large part on the extent to which reimbursement is available to medical institutions and their physicians for use of the Company's products.

The level of reimbursement provided by United States and foreign third-party payors varies according to a number of factors, including the medical procedure category, payor, location, outcome and cost. In the United States, many private health care insurance carriers follow the recommendations of HCFA, which establishes guidelines for the reimbursement of health care providers treating Medicare and Medicaid patients. Internationally, healthcare reimbursement systems vary significantly. In certain countries, medical center budgets are fixed regardless of levels of patient treatment. In other countries, such as Japan, reimbursement from government or third party payors must be applied for and approved. As of the date of this Prospectus, under HCFA guidelines, Medicare reimburses medical institutions for Medicare patients based on the category of surgical procedures in which the BVS is used and incrementally reimburses physicians for the use of the BVS. Medicare does not, however, currently reimburse medical institutions for the incremental cost of using the BVS above the amount allowed for the reimbursement category of the surgical procedure. Certain private health insurers and managed care providers provide incremental reimbursement to both the medical institutions and their physicians. The Company is currently petitioning HCFA to assign a higher paying reimbursement category whenever the BVS is used. In October 1995, HCFA established a special "ICD-9" code for the BVS in an effort to more clearly track and evaluate hospital and physician costs associated specifically with the BVS compared to current reimbursement levels, so that HCFA can determine the appropriate category and level of reimbursement. There can be no assurance that HCFA will reassign the BVS to a higher paying category in a timely manner, if at all.

No reimbursement levels have been established for the Company's products under development, including the TAH. Prior to approving coverage for new medical devices, most third-party payors require evidence that the product has received FDA approval or clearance for marketing, is safe and effective and not experimental or investigational, and is medically necessary and appropriate for the specific patient for whom the product is being used. Increasing numbers of third-party payors require evidence that the procedures in which the products are used, as well as the products themselves, are cost- effective. There can be no assurance that the Company's products under development will meet these criteria, that third-party payors will reimburse physicians and medical institutions for the use of the products or that the level of reimbursement will be sufficient to support the widespread use of the products. Furthermore, there can be no assurance that third-party payors will continue to provide reimbursement for the use of BVS or that such payors will not reduce the current level of reimbursement for the product. Failure to achieve adequate reimbursement for its current or proposed products would have a material adverse effect on the Company's business, financial condition and results of operations.

ABIODENT SUBSIDIARY

ABIODENT, Inc. ("ABIODENT"), a wholly owned subsidiary of the Company, manufactures and markets the PerioTemp periodontal screening system ("PerioTemp") and markets the Halimeter for early detection and assessment of risk of periodontal disease and other sources of halitosis. ABIODENT is operated independently from the Company's cardiac assist activities. As of September 29, 1997, ABIODENT employed eight full-time employees.

The PerioTemp is a tool for use by dentists, periodontists and other dental specialists to instantly detect sites of gum inflammation. The PerioTemp patented technology, developed in part through funding from the National Institute of Dental Research, consists of a book-sized console, containing a microprocessor that is

33

connected to a probe, shaped much like a dentist's probe, with a heat-sensing tip. The device is used in a manner which is consistent with traditional probing but includes an instantaneous display and record of temperature deviations from normal inside the pockets between teeth and the surrounding gum. According to published sources, gum temperature has been shown to be a reliable indicator of the presence of inflammation, a precursor of periodontal disease. The PerioTemp also allows the clinician to record gum pocket depth and bleeding point information.

ABIODENT markets the PerioTemp in conjunction with the Halimeter, to provide differential evaluation of the sources of halitosis. ABIODENT purchases the Halimeter from Interscan, Inc. under a distribution arrangement which is exclusive to ABIODENT if it meets certain defined sales volume levels.

ABIODENT markets its dental products with complementary products of others used in preventive and cosmetic dental programs. Revenues from this subsidiary have represented less than ten percent of the Company's total revenues in all periods presented in this Prospectus. The Company believes that it cannot alone adequately support the investment that the continued growth of its dental business requires and is looking for alternative ways to support its dental business.

PATENTS AND PROPRIETARY RIGHTS

The Company's business depends significantly upon its proprietary technology. The Company relies on a combination of trade secret laws, patents, copyrights, trademarks and confidentiality agreements and other contractual provisions to establish, maintain and protect its proprietary rights, all of which afford only limited protection. There can be no assurance that others will not independently develop substantially equivalent proprietary information and techniques or otherwise gain access to the Company's trade secrets or disclose such technology or that the Company can meaningfully protect its trade secrets.

The Company has been issued or allowed 22 patents and has pending three patent applications in the United States. The Company has obtained or applied for corresponding patents and patent applications for certain of these patents and patent applications in a limited number of foreign countries. These patents relate to the BVS and certain of its products under development including the TAH. The Company's United States patents expire at various times from 2003 to 2016. There can be no assurance that the Company's pending patent applications or any future applications will be approved, that any patents will provide the Company with competitive advantages or will not be challenged by third parties, or that the patents of others will not render the Company's patents obsolete or otherwise have an adverse effect on the Company's ability to conduct business. Because foreign patents may afford less protection under foreign law than is available under United States patent law, there can be no assurance that any such patents issued to the Company will adequately protect the Company's proprietary information. Others may have filed and may file patent applications in the future that are similar or identical to those of the Company. To determine the priority of inventions, the Company may have to participate in interference proceedings declared by the United States Patent and Trademark Office or opposition proceedings before a foreign patent office that could result in substantial cost to the Company. No assurance can be given that any such interfering patent or patent application will not have priority over patent applications filed on behalf of the Company or that the Company will prevail in any opposition proceeding.

The medical device industry is characterized by a large number of patents and by frequent and substantial intellectual property litigation. There can be no assurance that the Company's products and technologies do not infringe any patents or proprietary rights of third parties. The Company may in the future be notified that it may be infringing intellectual property rights possessed by others. Any intellectual property litigation would be costly and could divert the efforts and attention of the Company's management and technical personnel, which could have a material adverse effect on the Company's business, financial condition and results of operations. There can be no assurance that infringement claims will not be asserted in the future or such assertions, if proven to be true, will not prevent the Company from selling its products or materially and adversely affect the Company's business, financial condition and results of operations. If any such claims

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are asserted against the Company's intellectual property rights, it may seek to enter into a royalty or licensing arrangement. There can be no assurance, however, that a license will be available on reasonable terms, or at all. The Company could decide, in the alternative, to resort to litigation to challenge such claims or to design around the patented technology. Such actions could be costly and would divert the efforts and attention of the Company's management and technical personnel, which would materially and adversely affect the Company's business, financial condition and results of operations.

Certain of the Company's products have been developed in part under government contracts pursuant to which the Company may be required to manufacture a substantial portion of the product in the United States and the government may obtain certain rights to use or disclose technical data developed under those contracts. The Company retains the right to obtain patents on any inventions developed under those contracts (subject to a non- exclusive, non-transferable, royalty-free license to the government), provided it follows certain prescribed procedures.

The Company purchased certain of its technology, including technology incorporated in the BVS, from the Abiomed Limited Partnership (the "Partnership"), in which the Company has a 61.7% interest. As a result of this purchase, the Company is required to pay the Partnership a royalty through August 3, 2000. See Note 7 to the Consolidated Financial Statements.

GOVERNMENT REGULATION

Clinical testing, manufacture and sale of the Company's products and products under development, including the BVS, TAH and Heart Booster and the Company's dental devices, are or will be subject to regulation by the FDA and corresponding state and foreign regulatory agencies. Noncompliance with applicable requirements can result in, among other things, fines, injunctions, civil penalties, recall or seizure of products, total or partial suspension of production, failure of the government to grant pre-market clearance or pre- market approval for devices, withdrawal of marketing approvals and criminal prosecution. The FDA also has the authority to request repair, replacement or refund of the cost of any device manufactured or distributed by the Company.

In the United States, medical devices are classified into one of three classes (i.e., Class I, II or III) on the basis of the controls deemed necessary by the FDA to reasonably ensure their safety and effectiveness. Class I devices are subject to general controls, such as labeling, pre-market notification and adherence to the FDA's Current Good Manufacturing Practices requirements set forth in the Quality System Regulation ("QSR"), which include testing, control and documentation requirements. Class II devices are subject to general and special controls, such as performance standards, post-market surveillance, patient registries and QSR compliance. Class III devices,,which are typically life-sustaining, life-supporting and implantable devices, or new devices that have been found not to be substantially equivalent to legally marketed devices, are subject to the requirements applicable to Class I and Class II devices and must generally also receive pre-market approval by the FDA to ensure their safety and effectiveness.

Before introducing a new device into the market, the Company must generally obtain FDA clearance or approval through either clearance of a 510(k) notification or receipt of a Pre-Market Approval ("PMA"). A 510(k) clearance will be granted if the submitted information establishes that the proposed device is "substantially equivalent" to a legally marketed Class I or Class II medical device or a Class III medical device for which the FDA has not required PMAs. The Company has received FDA market clearance under Section 510(k) for the PerioTemp.

A PMA application must be filed if a proposed device is not substantially equivalent to a legally marketed Class I or Class II device, or if it is a Class III device for which the FDA has required PMAs. A PMA application must be supported by valid scientific evidence, which typically includes extensive information including relevant bench tests, laboratory and animal studies and clinical trial data to demonstrate the safety and effectiveness of the device. The PMA application also must contain a complete description of the device

35

and its components, a detailed description of the methods, facilities and controls used to manufacture the device, and the proposed labeling advertising literature and training materials. By regulation, the FDA has 180 days to review the PMA application, and during that time an advisory committee may evaluate the application and provide recommendations to the FDA. Advisory Committee reviews often occur over a significantly protracted period, and a number of devices for which FDA approval has been sought have never been cleared for marketing. In addition, modifications to a device that is the subject of an approved PMA, or to its labeling or manufacturing process, may require approval by the FDA, including the submission of PMA supplements or new PMAs.

If clinical trials of a device are required in order to obtain FDA approval and the device presents a "significant risk," the sponsor of the trial will have to file an Investigational Device Exemption ("IDE") application prior to commencing clinical trials. The IDE application must be supported by data, which typically includes the results of animal and laboratory testing. If the IDE application is approved by the FDA and all of the appropriate Institutional Review Boards ("IRBs"), clinical trials may begin at a specific number of investigational sites with a specific number of patients, as approved by the FDA. If the device presents a "nonsignificant risk" to the patient, a sponsor may begin the clinical trial after obtaining approval for the study by one or more appropriate IRBs without the need for FDA approval. Sponsors of clinical trials are permitted to charge for investigational devices distributed in the course of the study provided that compensation does not exceed recovery of the costs of manufacture, research, development and handling. An IDE supplement must be submitted to and approved by the FDA before a sponsor or investigator may make a change to the investigational plan that may affect its scientific soundness or the rights, safety or welfare of human subjects.

In November 1992, the Company received PMA approval from the FDA for the BVS. In 1996 and 1997, the FDA approved the use of the BVS for additional indications, expanding its use to the treatment of all patients with reversible heart failure. The TAH and the Heart Booster will be Class III devices and therefore will be subject to the IDE and PMA processes and the QSR.

Any devices, including the BVS, that are manufactured or distributed by the Company pursuant to FDA clearances or approvals are subject to pervasive and continuing regulation by the FDA and certain state agencies. Manufacturers of medical devices for marketing in the United States are required to adhere to the QSR and must also comply with Medical Devices Reporting ("MDR") requirements that a firm report to the FDA any incident in which its product may have caused or contributed to a death or serious injury, or in which its product malfunctioned and, if the malfunction were to recur, it would be likely to cause or contribute to a death or serious injury. Labeling and promotional activities are subject to scrutiny by the FDA and, in certain circumstances, by the Federal Trade Commission. Current FDA enforcement policy prohibits the marketing of approved medical devices for unapproved uses. The Company is subject to routine inspection by the FDA and certain state agencies for compliance with the QSR and MDR requirements, as well as other applicable regulations.

In addition, the FDA requires that manufacturers of certain devices, including the BVS, conduct postmarket surveillance studies after receiving approval of a PMA application. The primary purpose of required postmarket surveillance is to provide an early warning system to alert the health care community to any potential problems with a device within a reasonable time of the initial marketing of the device. Postmarket surveillance provides clinical monitoring of the early experiences with the device once it is distributed in the general population under actual conditions of use.

The Company is also subject to regulation in each of the foreign countries in which it sells its products. Many of the regulations applicable to the Company's products in these counties are similar to those of the FDA. The Company has obtained the requisite foreign regulatory approvals for sale of the BVS in many foreign countries, including most of Western Europe, and has recently commenced the regulatory approval process in Japan. The Company believes that foreign regulations relating to the manufacture and sale of medical devices are becoming more stringent. The European Union has adopted regulations requiring that medical devices comply with the Medical Device Directive by June 15, 1998, which includes ISO-9001 and

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CE certification. The Company's BVS currently has German MedGV approval but is not yet certified for ISO-9001 compliance. The Company is working to obtain ISO-9001 and independent CE certification for its BVS facility. There can be no assurance that the Company will obtain such certification in a timely manner, if at all. Unless ISO and CE certification are obtained, the Company's sale of the BVS into the European Union may be restricted. Many manufacturers of medical devices, including the Company, have often relied on foreign markets for the initial commercial introduction of their products. The more stringent foreign regulatory environment could make it more difficult, costly and time consuming for the Company to pursue this strategy for new products.

Any FDA, foreign or state regulatory approvals or clearances, once obtained, can be withdrawn or modified. Delay in the Company obtaining, or inability of the Company to obtain and maintain, any necessary United States or foreign clearances or approvals for new or existing products or product enhancements, or cost overruns resulting from these regulatory requirements, would have a material adverse effect on the Company's business, financial condition and results of operations.

EMPLOYEES

As of September 29, 1997, the Company had 166 full-time employees. The Company has entered into contractual agreements with all of its employees which include strict confidentiality and non-compete commitments by each employee. None of the Company's employees is represented by a union. The Company considers its employee relations to be good.

PROPERTIES

The Company leases its headquarters and research and development and production facilities in three separate buildings in an industrial office park covering approximately 55,000 square feet. The addresses of these leased spaces are 33 Cherry Hill Drive and 24 Cherry Hill Drive in Danvers, Massachusetts and 66 Cherry Hill Drive in Beverly, Massachusetts. All facilities are located approximately 22 miles north of Boston. The leases at the primary facilities, representing 23,000 square feet and 22,000 square feet, respectively, expire in April 2000 and June 2001, respectively. All leases have options to extend at market rates.

The Company's facilities include fabrication areas for medical and dental device manufacturing, and development facilities for laboratory and durability testing of plastics and electronics. The Company has begun improving approximately 18,000 square feet of this space to better accommodate its BVS growth and to allow for expanded engineering, production and testing relating to the TAH. The Company believes that these facilities are adequate for its current needs.

LEGAL PROCEEDINGS

The Company is not a party to any material pending legal proceedings.

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MANAGEMENT

EXECUTIVE OFFICERS, KEY EMPLOYEES AND DIRECTORS

The Company's executive officers, key employees and directors are as follows:

                NAME                  AGE                TITLE
------------------------------------- --- ------------------------------------
David M. Lederman, Ph.D*............. 53  Chairman of the Board of Directors,
                                           President, Chief Executive Officer
                                           and Assistant Treasurer
Robert T.V. Kung, Ph.D*.............. 53  Senior Vice President--Research and
                                           Development, Assistant Secretary
Eugene D. Rabe*...................... 41  Vice President--Global Sales,
                                           Marketing and Clinical Programs
John F. Thero*....................... 37  Vice President--Finance, Chief
                                           Financial Officer, Treasurer and
                                           Assistant Secretary
Anthony W. Bailey.................... 41  Vice President--Engineering
William J. Bolt...................... 45  Vice President (in charge of
                                           ABIODENT)
David Nikka.......................... 42  Vice President--Resources and
                                           Administration
Janice Piasecki...................... 43  Vice President--Regulatory Affairs
Edward G. Taylor, Ph.D............... 46  Vice President--Program Director,
                                           Implantable Artificial Heart
W. Gerald Austen, M.D................ 67  Director
Paul Fireman......................... 53  Director
John F. O'Brien...................... 54  Director
Desmond H. O'Connell, Jr. ........... 61  Director
Henri A. Termeer..................... 51  Director


*Executive Officer

Dr. David M. Lederman founded the Company in 1981, has served as Chairman of the Board and Chief Executive Officer since that time, and as President for the majority of that time. Prior to founding ABIOMED, he was Chairman of the Medical Research Group at the Everett Subsidiary of Avco Corporation. He originated the design and development of ABIOMED's artificial heart blood pumps and their valves, has authored over 40 medical publications, is a member of numerous medical and scientific professional organizations and has been a frequent speaker in forums on cardiac support systems and on the financing and commercialization of advanced medical technology. Dr. Lederman received a Ph.D. degree in Aerospace Engineering from Cornell University.

Dr. Robert T.V. Kung has served as Vice President of Research and Development of the Company since 1987. From 1982 to 1987, he served as Chief Scientist of the Company. Since 1995, Dr. Kung has served as the Senior Vice President of the Company. Prior to joining ABIOMED, he was a Principal Research Scientist at Schafer Associates and at the Avco Everett Research Laboratory. He developed non-linear optical techniques for laser applications and investigated physical and chemical phenomena in re-entry physics. Dr. Kung has been Principal Investigator for the Company's TAH and Heart Booster programs and has conceived of and directed the development of the Company's laser-based minimally invasive technologies, as well as the PerioTemp. Dr. Kung received a Ph.D. degree in Physical Chemistry from Cornell University.

Mr. Eugene D. Rabe joined the Company in 1993, as its Vice-President for Sales. In 1996, he assumed responsibility for all domestic sales, clinical and field support. Recently he was promoted to Vice-President Global Sales, Marketing and Clinical Programs. Prior to joining ABIOMED, he was Vice- President, Sales and

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Marketing for Endosonics Corporation before which he was a Sales Manager for St. Jude Medical, Inc. He has been involved in the sales and marketing of cardiovascular/cardiological devices for over ten years. Mr. Rabe received a Bachelor's degree from St. Cloud State University and his MBA from the University of California.

Mr. John F. Thero joined the Company in 1994 as Vice President, Finance and Administration and Chief Financial Officer. Prior to joining ABIOMED, during the period 1992 to 1995, Mr. Thero was Chief Financial Officer and acting President for the restructuring of two venture-backed companies. From 1987 to 1992, Mr. Thero was employed, in various capacities including Chief Financial Officer, by Aries Technology, Inc. From 1983 to 1987, Mr. Thero was employed by the commercial audit division of Arthur Andersen & Co. during which time he became a Certified Public Accountant. Mr. Thero received a B.A. in Economics/Accounting from The College of the Holy Cross.

Mr. Anthony W. Bailey joined the Company in 1997 to lead the Electronics System Development of the Implantable Artificial Heart Program and is currently Vice President--Engineering. Prior to joining ABIOMED, during 1987 to 1997, Mr. Bailey was Vice President and General Manager for Pace Medical, Inc., a manufacturer of external pacemakers, rhythm management analyzers and accessories. From 1982 to 1987, he was Manager of Design and Development at Shiley Infusaid, Inc., a manufacturer of implantable drug pumps and infusion ports. Prior to that, Mr. Bailey served in various engineering functions with manufacturers of implantable pacemakers, data acquisition and control systems and medical monitoring equipment. Mr. Bailey received his Bachelor's degree from University of Lowell.

Mr. William J. Bolt joined the Company in 1982. Since that time, he has served in various roles, from Director of Operations to Vice President of Engineering, and was the engineer in-charge when the BVS and PerioTemp systems were developed. He is presently responsible for the business operations of ABIODENT, including dental product sales, marketing, manufacturing and engineering support. Mr. Bolt received a Bachelor's degree in Electrical Engineering and a Masters degree in Business Administration from Northeastern University.

Mr. David Nikka joined the Company in 1997 as its Vice President--Resources and Administration. Prior to joining ABIOMED, he was Vice President, Human Resources from 1991 to 1997 for Genzyme Genetics, Director of Human Resources from 1989 to 1991 for Genzyme Corporation and Director of Human Resources for Integrated Genetics from 1986 to 1989. Mr. Nikka received his Bachelor Degree from Boston University. Mr. Nikka is past Chairperson of both the BIO and the Massachusetts Biotechnology Council Human Resource Committees.

Ms. Janice Piasecki joined the Company in 1991 as Manager of Clinical Research and Regulatory Affairs. In this role she has worked extensively on PMA submissions for the BVS which led to FDA approvals. She was promoted to Vice-President, Regulatory Affairs in 1994. Prior to joining ABIOMED, she held position of Investigator for the United States Food and Drug Administration and Manager of Regulatory Affairs for C.R. Bard. Ms. Piasecki received her B.S. degree in Biology and Chemistry from Boston College.

Dr. Edward G. Taylor joined the Company at the end of 1996 as Vice President and Director of the Artificial Heart Program. Prior to joining ABIOMED, Dr. Taylor worked in the United States Air Force from 1972 to 1996 where he attained the rank of Colonel and was most recently the Program Director for the Airborne Warning and Control System (AWACS) in the United States, Europe and Japan. Previously he had directed high technology research and development of nationally significant defense programs, including self-protection avionics for Air Force One. He was also involved in the launch and operation of reconnaissance and communication satellites. Dr. Taylor holds a Bachelor's degree from the Illinois Institute of Technology, a Master's degree from the Air Force Institute of Technology and a Ph.D. degree in Estimation and Control from the Massachusetts Institute of Technology.

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Dr. W. Gerald Austen has served as a director of the Company since 1985. From 1969 to the present, Dr. Austen has been Chief of the Surgical Services at Massachusetts General Hospital, and from 1974 to the present, has been the Edward D. Churchill Professor of Surgery at Harvard Medical School. He became President of the Massachusetts General Physicians Organization in 1994. Dr. Austen is the former President of the American College of Surgeons, the American Association for Thoracic Surgery, the American Surgical Association and the Massachusetts and American Heart Associations. Dr. Austen is a member of the Institute of Medicine of the National Academy of Sciences, a Fellow of the American Academy of Arts and Sciences and a life member of the corporation of the Massachusetts Institute of Technology.

Mr. Paul Fireman has served as a director of the Company since 1987. He is the founder of Reebok International Ltd., a leading worldwide designer, marketer and distributor of sports, fitness and casual footwear, apparel and equipment. Mr. Fireman has served as Chief Executive Officer and a director of that company since 1979, as Chairman of the Board of Directors since 1985 and President from 1979 to 1987 and since 1989. Mr. Fireman has also served as the chairman of the Entrepreneurial Advisory Board of Babson College since 1995.

Mr. John F. O'Brien has served as a director since 1989. Since August 1989 he has been the President and Chief Executive Officer and a director of First Allmerica Financial Life Insurance Company (formerly State Mutual Life Assurance Company of America). Since January 1995 he has been President, Chief Executive Officer and a Director of Allmerica Financial Corporation, a financial services holding company. Mr. O'Brien is also President, Chief Executive Officer and a director of Allmerica Property & Casualty Companies, Inc.; Chairman of the Board, President and Chief Executive Officer of Citizens Corporation; and a trustee and Chairman of the Board of Allmerica Securities Trust, Allmerica Investment Trust and Allmerica Funds. From 1972 until 1989, Mr. O'Brien was employed by Fidelity Investments in various capacities, including as Group Managing Director of FMR Corp. Mr. O'Brien is also a director of Cabot Corporation and TJX Companies, Inc. and a Trustee of the Worcester Art Museum.

Mr. Desmond H. O'Connell, Jr. has served as a director of the Company since 1995. He has been an independent management consultant since September 1990 and has served as a director of Chryslais International Corporation, an international contract research organization, since 1991. From December 1992 until December 1993, he served as the Chairman, Management Committee, of Pharmakon Research International, Inc., a provider of pre-clinical testing services to pharmaceutical biotechnology companies. During 1991, he briefly served as Chairman of the Board and Chief Executive Officer of Osteotech, Inc., a medical products company. Mr. O'Connell was with the BOC Group, PLC, an industrial gas and health care company, in senior management positions from 1980 to 1990 and was a member of the Board of Directors of BOC Group, PLC from 1983 to 1990. From April 1990 until September 1990, Mr. O'Connell was President and Chief Executive Officer of BOC Health Care. From 1986 to April 1990, he was Group Managing Director of BOC Group, PLC. Prior to joining BOC, Mr. O'Connell held various positions at Baxter Laboratories, Inc. including chief executive of the Therapeutic and Diagnostic Division and Vice President, Corporate Development.

Mr. Henri A. Termeer has served as a director of the Company since 1987. Mr. Termeer has served as President and a director of Genzyme, a biotechnology company engaged in the production and marketing of human health care products, since 1983, as its Chief Executive Officer since 1985, and as its Chairman of the Board since 1988. Mr. Termeer is also Chairman of the Board of Genzyme Transgenics Corporation. He is also a director of AutoImmune, Inc., GelTex Pharmaceuticals, Inc. and Diacrin, Inc. and serves as a trustee of Hambrecht & Quist Healthcare Investors and Hambrecht & Quist Life Sciences Investors.

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CERTAIN TRANSACTIONS

In July 1997, the Company sold a total of 1,242,710 shares of Common Stock to Genzyme and certain of the Company's directors for a purchase price of $13.00 per share, for a total purchase price of $16.2 million. The Chief Executive Officer of Genzyme, Henri A. Termeer, is a director of the Company. Of the shares sold, 1,153,846 shares were sold to Genzyme, 23,480 shares were sold to Paul Fireman, 7,692 shares were sold to Desmond H. O'Connell, Jr. and 57,692 shares were sold to John F. O'Brien. In addition, simultaneously with this transaction, David M. Lederman, the President and Chief Executive Officer of the Company sold 153,846 shares of Common Stock to Paul Fireman, a director of the Company. In connection with these transactions, the Company granted Genzyme certain registration rights with respect to the shares of Common Stock purchased by Genzyme. Commencing in July 1998, Genzyme may on up to three occasions require the Company to register not less than 25% of Genzyme's shares of Common Stock. Genzyme has also been granted certain piggyback registration rights to participate in underwritten public offerings by the Company, subject to certain limitations, commencing in July 1998. In addition, the other purchasers received similar piggyback registration rights commencing in July 1998, with respect to the 242,710 shares of Common Stock purchased by them. In connection with its purchase of the Common Stock, Genzyme agreed, subject to certain limited exceptions, not to acquire additional voting securities of the Company for a period of five years following the consummation of the transaction without the consent of the Company, and, during that five year period, to vote its shares in the same proportion as votes cast by other stockholders of the Company or, in Genzyme's discretion, in accordance with the recommendations of the Company's Board of Directors.

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PRINCIPAL AND SELLING STOCKHOLDERS

The following table sets forth certain information regarding the beneficial ownership of the Company's Common Stock as of September 26, 1997, and as adjusted to reflect the sale of the Common Stock offered hereby, (i) by each person who is known by the Company to own beneficially more than 5% of the outstanding shares of Common Stock, (ii) by each executive officer and director of the Company, (iii) by all executive officers and directors of the Company as a group and (iv) by each of the Selling Stockholders. This information is based upon information received from or on behalf of the named individuals. All Selling Stockholders are executive officers of the Company.

                           BENEFICIAL OWNERSHIP   NUMBER   BENEFICIAL OWNERSHIP
                           PRIOR TO OFFERING(1)     OF       AFTER OFFERING(1)
                          ----------------------- SHARES  -----------------------
                          NUMBER OF PERCENTAGE OF  BEING  NUMBER OF PERCENTAGE OF
                           SHARES     OWNERSHIP   OFFERED  SHARES     OWNERSHIP
                          --------- ------------- ------- --------- -------------
David M. Lederman,
 Ph.D(2)................  1,322,554     16.0%     115,000 1,207,554     11.5%
Genzyme Corporation.....  1,153,846     14.0%         --  1,153,846     11.0%
Robert T.V. Kung,
 Ph.D(3)(4).............    173,188      2.1%      35,000   138,188      1.3%
Eugene D. Rabe(4).......     18,750       *           --     18,750       *
John F. Thero(4)........      7,644       *           --      7,644       *
W. Gerald Austen,
 M.D.(4)................     25,400       *           --     25,400       *
Paul Fireman(4).........    225,226      2.7%         --    225,226      2.1%
John F. O'Brien(4)......     85,092      1.0%         --     85,092       *
Desmond H. O'Connell,
 Jr.(4).................     18,092       *           --     18,092       *
Henri A. Termeer(4)(5)..  1,179,246     14.2%         --  1,179,246     11.2%
All executive officers
 and directors as a
 group(2)(3)(4)(5) (9
 persons)...............  3,055,192     36.2%     150,000 2,905,192     27.2%


*Represents beneficial ownership of less than 1% of the outstanding shares of Common Stock.
(1) Beneficial ownership is determined in accordance with the rules of the Securities and Exchange Commission and generally includes voting or investment power with respect to securities. Beneficial ownership also includes shares of stock subject to options currently exercisable or exercisable within 60 days of September 26, 1997. Percentage of beneficial ownership is based on 8,263,007 shares of Common Stock outstanding on September 26, 1997 and 10,513,007 shares of Common Stock outstanding upon completion of this offering. Unless otherwise noted, each person identified possesses sole voting and investment power with respect to the shares listed.
(2) Includes 725,923 shares held by Dr. Lederman's wife, as to which Dr. Lederman disclaims beneficial ownership.
(3) Includes 60,000 shares held by Dr. Kung's wife and 12,000 shares held in trust for the benefit of certain relatives of Dr. Kung, as to which Dr. Kung disclaims beneficial ownership.
(4) Includes the following shares subject to options which are exercisable within 60 days after September 26, 1997: Dr. Kung--51,188; Mr. Rabe-- 18,750; Mr. Thero--7,500; Dr. Austen--25,000; Mr. Fireman--25,000; Mr. O'Brien--25,000; Mr. O"Connell--5,000; Mr. Termeer--25,000.
(5) Includes 1,153,846 shares held by Genzyme Corporation as to which Mr. Termeer disclaims beneficial ownership. Mr. Termeer is the Chief Executive Officer of Genzyme.

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DESCRIPTION OF CAPITAL STOCK

The Company's authorized capital stock consists of 25,000,000 shares of Common Stock, $.01 par value, and 1,000,000 shares of Class B Preferred Stock, $.01 par value ("Preferred Stock").

COMMON STOCK

As of September 26, 1997, there were 8,263,007 shares of Common Stock outstanding. These shares were held of record by approximately 340 stockholders, including multiple beneficial holders at depositories, banks and brokers listed as a single holder in the street name of each respective depository, bank or broker. There will be 10,513,007 shares of Common Stock outstanding after giving effect to the sale of the shares of Common Stock offered hereby by the Company.

The holders of Common Stock are entitled to one vote per share on all matters to be voted on by stockholders and are entitled to receive dividends, if any, as may be declared from time to time by the Board of Directors from funds legally available therefore. Upon liquidation or dissolution of the Company, the holders of Common Stock are entitled to receive all assets available for distribution to the stockholders, subject to any preferential or other rights of the holders of Preferred Stock. The Common Stock has no preemptive or other subscription rights, and there are no conversion rights or redemption or sinking fund provisions with respect to such shares. The holders of Common Stock do not have cumulative voting rights in the election of directors. All of the shares of Common Stock are, and the shares to be sold in the offering will be, fully paid and nonassessable.

PREFERRED STOCK

The Company has no Preferred Stock outstanding. The Board of Directors has the authority to issue the Preferred Stock in one or more series and to fix the dividend rights, dividend rate, conversion rights, voting rights, rights and terms of redemption, liquidation preferences, sinking fund terms and other rights, preferences, privileges and restrictions of any series of Preferred Stock, the number of shares constituting any such series and the designation thereof, without further vote or action by the stockholders. The Board of Directors may, without stockholder approval, issue Preferred Stock with rights and privileges which could, among other things, have the effect of delaying, deferring or preventing a change in control of the Company. The issuance of Preferred Stock with voting and conversion rights may adversely affect the voting power and other rights of the holders of Common Stock, including the loss of voting control to others. The Company currently has no plans to issue any of the Preferred Stock. The Board of Directors has designated 25,000 shares of the Preferred Stock as the "Series A Junior Participating Preferred Stock" in connection with the Rights described below.

ANTI-TAKEOVER EFFECT OF PROVISIONS OF THE CERTIFICATE OF INCORPORATION AND BY- LAWS, RIGHTS DISTRIBUTION AND DELAWARE LAW

Certificate of Incorporation and By-laws

The Certificate of Incorporation includes several provisions in addition to the Preferred Stock, which may render more difficult an unfriendly tender offer, proxy contest, merger or other change in control of the Company. These provisions are intended to enhance the likelihood of continuity and stability in the composition of the Board of Directors and in the policies formulated by the Board of Directors and to discourage certain types of transactions that may involve an actual or threatened change of control of the Company. These provisions are also designed to reduce the vulnerability of the Company to unsolicited acquisition proposals and to discourage certain tactics that may be used in proxy fights. However, such provisions could have the effect of discouraging others from making tender offers for the shares of Common Stock and, as a consequence, they also may inhibit fluctuations in the market price of the shares of Common Stock which could result from actual or rumored takeover attempts. Such factors also may have the effect of preventing changes in the management of the Company.

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The Certificate of Incorporation (i) provides for the classification of the Company's Board of Directors into three classes, (ii) eliminates the ability of stockholders to enlarge the Board of Directors, (iii) provides that vacancies in the office of a director shall be in the first instance filled by the remaining directors, except in the case of the directors elected by the Common Stock voting as a separate class, in which case it shall be filled by the holders of that class voting as a separate class, (iv) provides that directors may only be removed "for cause" and only by the class or classes of stock which elected them, and (v) requires an 80% affirmative vote of all votes entitled to be cast to amend the preceding provisions. The classification of directors has the effect of making it more difficult to change the composition of the Board of Directors. At least two stockholder meetings, instead of one, are required to effect a change in the control of the Board.

The By-laws provide that advance written notice of any stockholder nomination for director must be provided not less than 45 nor more than 60 days prior to the anticipated date of the annual meeting for election of directors.

The Certificate of Incorporation explicitly directs the Board of Directors to take into account all relevant factors in exercising its business judgment in determining what is in the best interests of the Company and its stockholders in evaluating certain tender offers and business combination proposals. Relevant factors include, without limitation, the Board's estimate of the future value of the Company, the resources and future prospects of the other party, and the possible social, legal, environmental and economic effects on the Company and on the employees, customers, suppliers and creditors of the Company and on the communities in which the Company's facilities are located.

The Certificate of Incorporation and the By-laws also provide that all stockholder action must be effected at a duly called meeting and not by written consent.

The authority of the Board of Directors to issue authorized but unissued shares of Common Stock might be considered as having the effect of discouraging an attempt by another person or entity to effect a takeover or otherwise gain control of the Company since the issuance of additional shares of Common Stock would dilute the voting power of the Common Stock then outstanding.

Rights Distribution

On August 13, 1997, the Board of Directors declared a dividend of one preferred share purchase right (a "Right") for each outstanding share of Common Stock on August 28, 1997 (the "Record Date") to the stockholders of record on that date. Each Right entitles the registered holder to purchase from the Company one one-thousandth of a share of Series A Junior Participating Preferred Stock, par value $0.01 per share (the "Preferred Shares"), of the Company, at a price of $90.00 per one one-thousandth of a Preferred Share, subject to adjustment.

Subject to certain limited exceptions until the earlier to occur of (i) ten days following a public announcement that a person or group of affiliated or associated persons (an "Acquiring Person") has acquired beneficial ownership of 15% or more of the outstanding shares of Common Stock, or (ii) ten business days (or such later date as may be determined by action of the Board of Directors prior to such time as any person becomes an Acquiring Person) following the commencement of, or announcement of an intention to make, a tender offer or exchange offer the consummation of which would result in the beneficial ownership by a person or group of 15% or more of the outstanding shares of Common Stock (the earlier of such dates being called the "Distribution Date"), the Rights will be evidenced by the Common Stock certificates with a copy of the Summary of Rights attached thereto. As soon as practicable following the Distribution Date, the rights will become exercisable, separate certificates evidencing the Rights ("Right Certificates") will be mailed to stockholders of record on the Distribution Date and the separate Right Certificates alone will evidence the Rights.

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The Rights will expire on the earlier of (i) August 13, 2007 or (ii) the date on which the Rights are redeemed.

In the event that any person becomes an Acquiring Person, proper provision will be made so that each holder of a Right, other than Rights beneficially owned by the Acquiring Person and its affiliates and associates (which will thereafter be void), will thereafter have the right to receive upon exercise, that number of shares of Common Stock having a market value of two times the exercise price of the Right. In the event that, at any time after a person becomes an Acquiring Person, the Company is acquired in a merger or other business combination transaction or 50% or more of its consolidated assets or earning power are sold, proper provision will be made so that each holder of a Right will thereafter have the right to receive, upon the exercise thereof at the then current exercise price of the Right, that number of shares of common stock of the acquiring company which at the time of such transaction will have a market value of two times the exercise price of the Right.

At any time after any person becomes an Acquiring Person and prior to the acquisition by any person or group of a majority of the outstanding shares of Common Stock, the Board of Directors may exchange the Rights (other than Rights owned by such person or group which have become void), in whole or in part, at an exchange ratio of one share of Common Stock per Right, subject to adjustment. At any time prior to the time any Person becomes an Acquiring Person, the Board of Directors of the Company may redeem the Rights in whole, but not in part, at a price of $0.001 per Right (the "Redemption Price"). The redemption of the Rights may be made effective at such time, on such basis and with such conditions as the Board of Directors in its sole discretion may establish. Immediately upon any redemption of the Rights, the right to exercise the Rights will terminate and the only right of the holders of Rights will be to receive the Redemption Price.

The terms of the Rights may be amended by the Board of Directors without the consent of the holders of the Rights, except that from and after such time as any person becomes an Acquiring Person no such amendment may adversely affect the interests of the holders of the Rights (other than the Acquiring Person and its affiliates and associates).

Delaware Takeover Statute

Pursuant to Delaware law, Delaware corporations are prohibited from engaging in a wide range of specified transactions with any "interested stockholder," defined to include, among others, any person or entity who in the last three years obtained 15% or more of any class or series of stock entitled to vote generally in the election of directors, unless, among other exceptions, the transaction is approved by (i) the Board of Directors prior to the date the interested stockholder obtained such status or (ii) the holders of two-thirds of the outstanding shares of each class or series of stock entitled to vote generally in the election of directors, not including those shares owned by the interested stockholder. By virtue of the Company's decision not to opt out of the provisions of this law, it applies to the Company.

TRANSFER AGENT AND REGISTRAR

The Transfer Agent and Registrar for the Common Stock is Boston EquiServe LP.

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UNDERWRITING

The Underwriters named below, acting through their representatives Robertson, Stephens & Company LLC and UBS Securities LLC (the "Representatives"), have severally agreed, subject to the terms and conditions of the Underwriting Agreement, to purchase from the Company and the Selling Stockholders the number of shares of Common Stock set forth opposite their names below. The Underwriters are committed to purchase and pay for all such shares, if any are purchased.

                                                                    NUMBER OF
UNDERWRITER                                                          SHARES
-----------                                                         ---------
Robertson, Stephens & Company LLC..................................
UBS Securities LLC.................................................



                                                                    ---------
    Total.......................................................... 2,400,000
                                                                    =========

The Representatives have advised the Company and the Selling Stockholders that the Underwriters propose to offer the shares of Common Stock to the public at the price to the public set forth on the cover page of this Prospectus and to certain dealers at such price less a concession of not more than $ per share, of which $ may be reallowed to other dealers. After the public offering, the public offering price, concession and reallowance to dealers may be reduced by the Representatives. No such reduction shall change the amount of proceeds to be received by the Company and Selling Stockholders as set forth on the cover page of this Prospectus.

The Company has granted to the Underwriters an option, exercisable during the 30-day period after the date of this Prospectus, to purchase up to 360,000 additional shares of Common Stock at the same price per share as the Company and Selling Stockholders will receive for the 2,400,000 shares that the Underwriters have agreed to purchase. To the extent that the Underwriters exercise such option, each of the Underwriters will have a firm commitment to purchase approximately the same percentage of such additional shares that the number of shares of Common Stock to be purchased by it shown in the above table represents as a percentage of the 2,400,000 shares offered hereby. If purchased, such additional shares will be sold by the Underwriters on the same terms as those on which the 2,400,000 shares are being sold. The Company will be obligated, pursuant to the option, to sell shares to the Underwriters to the extent the option is exercised. The Underwriters may exercise such option only to cover over-allotments made in connection with the sale of shares of Common Stock offered hereby.

46

The Underwriting Agreement contains covenants of indemnity among the Underwriters, the Company and the Selling Stockholders against certain civil liabilities, including liabilities under the Securities Act and liabilities arising from breaches of representations and warranties contained in the Underwriting Agreement.

The Company's executive officers, directors, Genzyme and each of the Selling Stockholders who, in the aggregate hold approximately 2,872,754 shares of Common Stock (2,722,754 shares of Common Stock after the sale of shares of Common Stock by the Selling Stockholders in the offering) have agreed in writing with the Representatives that, for a period of 90 days from the date of this Prospectus ("Lock-up Period"), subject to certain limited exceptions, each will not, directly or indirectly, without the prior written consent of Robertson, Stephens & Company LLC, sell, offer, contract to sell, pledge, grant any option to purchase or otherwise dispose of any shares of Common Stock or any securities convertible into or exchangeable for, or any rights to purchase or acquire, Common Stock held by them, thereafter acquired by them or which may be deemed to be beneficially owned by them. However, Robertson, Stephens & Company LLC may, in its sole discretion at any time or from time to time, without notice, release all or any portion of the securities subject to the lock-up agreements. In addition, the Company has agreed that during the Lock-up Period, it will not, without the prior written consent of Robertson, Stephens & Company LLC, issue, sell, contract to sell or otherwise dispose of any shares of Common Stock, any options or warrants to purchase any shares of Common Stock or any securities convertible into, exercisable for or exchangeable for shares of Common Stock other than the Company's sale of shares in this offering, the issuance of Common Stock upon the exercise of outstanding options and under the Company's existing employee stock purchase plan, the Company's issuance of options under existing employee and director stock options plans and under certain other conditions. See "Risk Factors-- Shares Eligible For Future Sale."

The offering price for the Common Stock has been determined by negotiations among the Company, the Selling Stockholders and the Representatives of the Underwriters, based largely upon the market price for the Common Stock as reported on the Nasdaq National Market.

The Underwriters do not intend to confirm sales to any accounts over which they exercise discretionary authority in excess of 5% of the number of shares of Common Stock offered hereby.

The Representatives have advised the Company that, pursuant to Regulation M under the Securities Act, certain persons participating in the offering may engage in transactions, including stabilizing bids, syndicate covering transactions or the imposition of penalty bids, which may have the effect of stabilizing or maintaining the market price of the Common Stock at a level above that which might otherwise prevail in the open market. A "stabilizing bid" is a bid for or the purchase of the Common Stock on behalf of the Underwriters for the purpose of fixing or maintaining the price of the Common Stock. A "syndicate covering transaction" is the bid for or the purchase of the Common Stock on behalf of the Underwriters to reduce a short position incurred by the Underwriters in connection with the offering. A "penalty bid" is an arrangement permitting the Representatives to reclaim the selling concession otherwise accruing to an Underwriter or syndicate member in connection with the offering if the Common Stock originally sold by such Underwriter or syndicate member is purchased by the Representatives in a syndicate covering transaction and has therefore not been effectively placed by such Underwriter or syndicate member. The Representatives have advised the Company that such transactions may be effected on the Nasdaq National Market or otherwise and, if commenced, may be discontinued at any time.

In connection with this offering, certain Underwriters may engage in passive market making transactions in the Common Stock on the Nasdaq Stock Market in accordance with Rule 103 of Regulation M under the Securities Exchange Act of 1934 ("Exchange Act"). Passive market making consists of displaying bids on the Nasdaq National Market limited by the bid prices of independent market makers and making purchases limited by such prices and effected in response to order flow. Net purchases by a passive market maker on each day are limited to a specific percentage of the passive market maker's average daily trading volume in the Common Stock during a specific period and must be discontinued when such limit is reached. Passive market making may stabilize the market price of the Common Stock at a level above that which might otherwise prevail and, if commenced, may be discontinued at any time.

47

Since September 1996, an entity affiliated with UBS Securities LLC has managed certain assets of the Company, primarily in the form of marketable securities, held by ABD Holding, Inc., a wholly owned subsidiary of the Company. The Company pays quarterly fees for such services based on a percentage of the assets managed. UBS Securities LLC also received fees in connection with its role as the Company's financial advisor in connection with the implementation of a stockholder rights plan for the holders of the Company's Common Stock in August 1997 and its opinion as to the fairness from a financial point of view of the consideration received by the Company pursuant to a private placement of the Company's Common Stock in July 1997. See "Certain Transactions."

On June 8, 1997, the parent entities of Robertson, Stephens & Company LLC agreed to be acquired by BankAmerica Corporation ("Acquisition"). In connection with the Acquisition, Robertson, Stephens & Company LLC will be merged with and into BancAmerica Securities, Inc., and the resulting entity will be named BancAmerica Robertson Stephens.

LEGAL MATTERS

The validity of the securities offered hereby has been passed upon for the Company and the Selling Stockholders by Brown, Rudnick, Freed & Gesmer, Boston, Massachusetts. Certain legal matters in connection with this offering will be passed upon for the Underwriters by Testa, Hurwitz & Thibeault, LLP, Boston, Massachusetts. A member of Brown, Rudnick, Freed & Gesmer, counsel to the Company, is the Secretary of the Company.

EXPERTS

The financial statements included or incorporated by reference in this Prospectus or elsewhere in this Registration Statement have been audited by Arthur Andersen LLP, independent public accountants, as indicated in their report with respect thereto, and are included or incorporated by reference herein upon the authority of said firm as experts in giving said report.

AVAILABLE INFORMATION

The Company is subject to the informational requirements of the Exchange Act, and in accordance therewith files reports, proxy statements and other information with the Commission. Such reports, proxy statements and other information filed by the Company can be inspected and copied at the public reference facilities maintained by the Commission at 450 Fifth Street, NW, Room 1024, Judiciary Plaza, Washington, D.C. 20549, and at the Commission's Regional Offices at Citicorp Center, 500 West Madison Street, Suite 1400, Chicago, Illinois 60661 and 7 World Trade Center, Suite 1300, New York, New York 10048, at prescribed rates. In addition, such reports, proxy statements and information are available through the Commission's Electronic Data Gathering and Retrieval System at http://www.sec.gov. The Company's Common Stock is listed on the Nasdaq National Market, and reports, proxy statements and certain other information concerning the Company can also be inspected at the offices of the Nasdaq National Market, 1735 K Street NW, Washington, D.C. 20006.

The Company has filed with the Commission a Registration Statement on Form S-3 under the Securities Act of 1933, as amended, with respect to the Common Stock being offered hereby. This Prospectus, which constitutes a part of the Registration Statement, does not contain all of the information set forth in such Registration Statement and the exhibits and schedules thereto to which reference is hereby made. The statements in this Prospectus as to the contents of such Registration Statement are qualified in their entirety by such reference. The Registration Statement, together with its exhibits and schedules, may be inspected without charge at the Public Reference Section of the Commission in Washington, D.C. at the address noted above, and copies of all or any part thereof may be obtained from the Commission upon payment of the prescribed fees.

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INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

The following documents filed by the Company with the Commission pursuant to the Exchange Act are incorporated herein by reference:

(1) the Company's Annual Report on Form 10-K for the fiscal year ended March 31, 1997;

(2) the Company's Quarterly Report on Form 10-Q for the fiscal quarter ended June 30, 1997;

(3) the Company's Current Report on Form 8-K filed with the Commission on August 25, 1997; and

(4) the description of the Company's Common Stock and the Rights contained in the Company's Registration Statements on Form 8-A filed with the Commission on June 11, 1987 and August 25, 1997.

All reports and other documents subsequently filed by the Company pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date of this Prospectus and prior to the termination of the offering shall be deemed to be incorporated by reference in this Prospectus and shall be part hereof from the date of the filing of such document. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Prospectus to the extent that a statement contained herein, or in any other subsequently filed document that also is (or is deemed to be) incorporated by reference herein, modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of the Registration Statement or this Prospectus. The Company will provide without charge to each person, including any beneficial owner, to whom this Prospectus is delivered, upon written or oral request of such person, a copy of any of the documents referred to above (other than exhibits). Requests for such documents should be submitted in writing to: Investor Relations, ABIOMED, Inc., Cherry Hill Drive, Danvers, Massachusetts 01923, or by telephone at
(978) 777-5410.

49

ABIOMED, INC. AND SUBSIDIARIES

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

                                                                            PAGE
                                                                            ----
Report of Independent Public Accountants..................................  F-2
Consolidated Balance Sheets as of March 31, 1996 and 1997, June 30, 1997
 (unaudited) and Pro Forma June 30, 1997 (unaudited)......................  F-3
Consolidated Statements of Operations for the Fiscal Years Ended March 31,
 1995, 1996 and 1997 and for the Three Months Ended June 30, 1996 and 1997
 (unaudited)..............................................................  F-4
Consolidated Statements of Stockholders' Investment for the Fiscal Years
 Ended March 31, 1995, 1996 and 1997 and for the Three Months Ended June
 30, 1997 (unaudited) and Pro Forma June 30, 1997 (unaudited).............  F-5
Consolidated Statements of Cash Flows for the Fiscal Years Ended March 31,
 1995, 1996 and 1997 and for the Three Months Ended June 30, 1996 and 1997
 (unaudited)..............................................................  F-6
Notes to Consolidated Financial Statements................................  F-7

F-1

ABIOMED, INC. AND SUBSIDIARIES

REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS

To ABIOMED, Inc.:

We have audited the accompanying consolidated balance sheets of ABIOMED, Inc. (a Delaware corporation) and subsidiaries as of March 31, 1996 and 1997, and the related consolidated statements of operations, stockholders' investment and cash flows for each of the three years in the period ended March 31, 1997. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits.

We conducted our audits in accordance with generally accepted auditing standards. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of ABIOMED, Inc. and subsidiaries as of March 31, 1996 and 1997, and the results of their operations and their cash flows for each of the three years in the period ended March 31, 1997, in conformity with generally accepted accounting principles.

                                          /s/ Arthur Andersen LLP

Boston, Massachusetts
May 8, 1997

F-2

ABIOMED, INC. AND SUBSIDIARIES

CONSOLIDATED BALANCE SHEETS

                                  MARCH 31,                   JUNE 30,
                          --------------------------  --------------------------
                              1996          1997          1997       PRO-FORMA
                          ------------  ------------  ------------  ------------
                                                      (unaudited)   (unaudited)
                                                                     (Note 10)
                      ASSETS
Current Assets:
  Cash and cash
   equivalents (Note
   1)...................  $  2,938,332  $  1,616,696  $  1,605,276  $ 17,743,006
  Short-term marketable
   securities (Note 1)..     7,709,110     7,744,664     7,160,563     7,160,563
  Accounts receivable,
   net of allowance for
   doubtful accounts of
   $111,000, $229,000
   and $223,000 at
   March 31, 1996, 1997
   and June 30, 1997,
   respectively.........     2,606,289     4,816,500     5,860,089     5,860,089
  Inventories (Note 1)..     1,653,512     1,820,783     2,013,944     2,013,944
  Prepaid expenses and
   other current
   assets...............        92,280       173,172       203,162       203,162
                          ------------  ------------  ------------  ------------
    Total current
     assets.............    14,999,523    16,171,815    16,843,034    32,980,764
                          ------------  ------------  ------------  ------------
Property and Equipment,
 at cost (Note 1):
  Machinery and
   equipment............     2,378,851     3,147,837     3,620,677     3,620,677
  Furniture and fixtures
   .....................       156,048       241,867       349,791       349,791
  Leasehold
   improvements.........       378,998     1,118,677     1,186,047     1,186,047
                          ------------  ------------  ------------  ------------
                             2,913,897     4,508,381     5,156,515     5,156,515
  Less -- Accumulated
   depreciation and
   amortization.........     2,331,145     2,618,603     2,734,487     2,734,487
                          ------------  ------------  ------------  ------------
                               582,752     1,889,778     2,422,028     2,422,028
Other Assets, net (Note
 7):                           627,154       485,000       449,462       449,462
                          ------------  ------------  ------------  ------------
                          $ 16,209,429  $ 18,546,593  $ 19,714,524  $ 35,852,254
                          ============  ============  ============  ============
     LIABILITIES AND STOCKHOLDERS' INVESTMENT
Current Liabilities:
  Accounts Payable......  $    777,943  $  1,289,024  $  1,216,225  $  1,344,064
  Accrued expenses
   (Notes 8 and 9)......     1,486,981     2,032,506     2,336,031     2,336,031
                          ------------  ------------  ------------  ------------
    Total current
     liabilities........     2,264,924     3,321,530     3,552,256     3,680,095
                          ------------  ------------  ------------  ------------
Commitments (Notes 5 and
 7)
Stockholders' Investment
 (Notes 2 and 6):
  Class B Preferred
   Stock, $.01 par
   value --
   Authorized --
    1,000,000 shares
   issued and
   outstanding-- none...           --            --            --            --
  Common Stock, $.01 par
   value --
    Authorized --
   25,000,000 shares
   issued and
   outstanding --
   5,518,054, 7,008,282,
   7,017,872 and
   8,260,582 shares at
   March 31, 1996, March
   31, 1997, June 30,
   1997 and pro forma,
   respectively.........        55,180        70,082        70,179        82,606
  Class A Common Stock,
   $.01 par value --
   Authorized --
    2,346,000 shares
   issued and
   outstanding--
    1,428,000 shares at
   March 31, 1996 and
   none at March 31,
   1997, June 30, 1997
   and pro forma,
   respectively.........        14,280           --            --            --
Additional paid-in
 capital................    36,625,221    37,169,893    37,236,040    53,233,504
Accumulated deficit.....   (22,750,176)  (22,014,912)  (21,143,951)  (21,143,951)
                          ------------  ------------  ------------  ------------
Total stockholders'
 investment.............    13,944,505    15,225,063    16,162,268    32,172,159
                          ------------  ------------  ------------  ------------
                          $ 16,209,429  $ 18,546,593  $ 19,714,524  $ 35,852,254
                          ============  ============  ============  ============

The accompanying notes are an integral part of these consolidated financial statements.

F-3

ABIOMED, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF OPERATIONS

                                                                 THREE MONTHS ENDED
                               YEARS ENDED MARCH, 31,                 JUNE 30,
                         ------------------------------------- -----------------------
                            1995         1996         1997        1996        1997
                         -----------  -----------  ----------- ----------- -----------
                                                               (unaudited) (unaudited)
Revenues (Note 1):
  Products.............. $ 6,892,931  $ 9,725,332  $12,311,178 $2,868,349  $4,206,743
  Contracts.............   2,337,505    3,118,278    4,150,752    816,923   1,829,045
                         -----------  -----------  ----------- ----------  ----------
                           9,230,436   12,843,610   16,461,930  3,685,272   6,035,788
                         -----------  -----------  ----------- ----------  ----------
Costs and expenses:
  Cost of products......   3,288,833    3,921,319    5,360,449  1,048,699   1,529,278
  Research and
   development
   (Note 1).............   2,464,519    3,218,211    3,832,918    863,975   1,643,499
  Selling, general and
   administrative.......   4,278,392    5,740,830    7,068,403  1,519,593   2,116,545
                         -----------  -----------  ----------- ----------  ----------
                          10,031,744   12,880,360   16,261,770  3,432,267   5,289,322
                         -----------  -----------  ----------- ----------  ----------
Income (loss) from
 operations.............    (801,308)     (36,750)     200,160    253,005     746,466
  Interest and other
   income...............     449,124      527,874      535,104    130,224     124,495
                         -----------  -----------  ----------- ----------  ----------
Net income (loss)....... $  (352,184) $   491,124  $   735,264 $  383,229  $  870,961
                         ===========  ===========  =========== ==========  ==========
Net income (loss) per
 common and common
 equivalent share (Note
 1)..................... $     (0.05) $      0.07  $      0.10 $     0.05  $     0.12
                         ===========  ===========  =========== ==========  ==========
Weighted average number
 of common and common
 equivalent shares
 outstanding (Note 1)...   6,511,777    6,995,664    7,162,347  7,206,261   7,567,333
                         ===========  ===========  =========== ==========  ==========

The accompanying notes are an integral part of these consolidated financial statements.

F-4

ABIOMED, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' INVESTMENT

                                                   CLASS A
                            COMMON STOCK         COMMON STOCK
                         ------------------- --------------------- ADDITIONAL                    TOTAL
                          NUMBER     $0.01     NUMBER      $0.01     PAID-IN   ACCUMULATED   STOCKHOLDERS'
                         OF SHARES PAR VALUE OF SHARES   PAR VALUE   CAPITAL     DEFICIT      INVESTMENT
                         --------- --------- ----------  --------- ----------- ------------  -------------
Balance, March 31,
 1994................... 4,432,686  $44,327   2,040,000   $20,400  $33,413,242 $(22,889,116)  $10,588,853
 Stock options
  exercised.............     1,100       11         --        --         6,314          --          6,325
 Stock issued under
  employee stock
  purchase plan.........       639        7         --        --         3,873          --          3,880
 Stock issued in
  exchange for amount
  due to Abiomed Limited
  Partnership...........   451,427    4,514         --        --     3,053,341          --      3,057,855
 Net loss...............       --       --          --        --           --      (352,184)     (352,184)
                         ---------  -------  ----------   -------  ----------- ------------   -----------
Balance, March 31,
 1995................... 4,885,852   48,859   2,040,000    20,400   36,476,770  (23,241,300)   13,304,729
 Conversion of Class A
  Common Stock to Common
  Stock.................   612,000    6,120    (612,000)   (6,120)         --           --            --
 Stock options
  exercised.............    19,425      194         --        --       143,018          --        143,212
 Stock issued under
  employee stock
  purchase plan.........       777        7         --        --         5,433          --          5,440
 Net income.............       --       --          --        --           --       491,124       491,124
                         ---------  -------  ----------   -------  ----------- ------------   -----------
Balance, March 31,
 1996................... 5,518,054   55,180   1,428,000    14,280   36,625,221  (22,750,176)   13,944,505
 Conversion of Class A
  Common Stock to Common
  Stock................. 1,428,000   14,280  (1,428,000)  (14,280)         --           --            --
 Stock options
  exercised.............    59,112      611         --        --       533,142          --        533,753
 Stock issued to
  directors and under
  employee stock
  purchase plan.........     3,116       11         --        --        11,530          --         11,541
 Net income.............       --       --          --        --           --       735,264       735,264
                         ---------  -------  ----------   -------  ----------- ------------   -----------
Balance, March 31,
 1997................... 7,008,282   70,082         --        --    37,169,893  (22,014,912)   15,225,063
 Stock options
  exercised.............     9,590       97         --        --        66,147          --         66,244
 Net income.............       --       --          --        --           --       870,961       870,961
                         ---------  -------  ----------   -------  ----------- ------------   -----------
Balance, June 30, 1997
 (unaudited)............ 7,017,872   70,179         --        --    37,236,040  (21,143,951)   16,162,268
 Pro forma effect of
  private placement of
  Common Stock ......... 1,242,710   12,427         --        --    15,997,464          --     16,009,891
                         ---------  -------  ----------   -------  ----------- ------------   -----------
Pro forma balance,
 June 30, 1997
 (unaudited)............ 8,260,582  $82,606         --    $   --   $53,233,504 $(21,143,951)  $32,172,159
                         =========  =======  ==========   =======  =========== ============   ===========

The accompanying notes are an integral part of these consolidated financial statements.

F-5

ABIOMED, INC. AND SUBSIDIARIES

CONSOLIDATED STATEMENTS OF CASH FLOWS

                                YEARS ENDED MARCH 31,          THREE MONTHS ENDED JUNE 30,
                           ----------------------------------  ----------------------------
                             1995        1996        1997          1996           1997
                           ---------  ----------  -----------  -------------  -------------
                                                                (unaudited)    (unaudited)
Cash flows from operating
 activities:
 Net income (loss).......  $(352,184) $  491,124  $   735,264  $     383,229  $     870,961
 Adjustments to reconcile
  net income (loss) to
  net cash provided by
  (used in) operating
  activities --
  Depreciation and
   amortization..........    353,293     349,756      429,612         96,084        151,422
  Noncash transactions
   related to Abiomed
   Limited Partnership...   (251,883)        --           --             --             --
  Changes in current
   assets and
   liabilities --
   Accounts receivable...    (73,518)   (830,555)  (2,210,211)       194,412     (1,043,589)
   Inventories...........    815,518    (244,232)    (167,271)       (28,667)      (193,161)
   Prepaid expenses and
    other current
    assets...............     58,530     (38,450)     (80,892)       (87,077)       (29,990)
   Accounts payable......    (65,894)    579,663      511,081       (169,637)       (72,799)
   Accrued expenses......    428,244     259,602      545,525       (230,653)       303,525
                           ---------  ----------  -----------  -------------  -------------
     Net cash provided by
      (used in) operating
      activities.........    912,106     566,908     (236,892)       157,691        (13,631)
                           ---------  ----------  -----------  -------------  -------------
Cash flows from investing
 activities:
 (Purchases) maturities
  of short term
  marketable security
  investments, net.......   (604,618)  2,701,323      (35,554)    (1,767,851)       584,101
 Purchases of property
  and equipment..........   (132,087)   (322,642)  (1,594,484)      (143,735)      (648,134)
 Purchases of Abiomed
  Limited Partnership
  units from limited
  partners (Note 7)......        --     (770,000)         --             --             --
                           ---------  ----------  -----------  -------------  -------------
     Net cash provided by
      (used in) investing
      activities.........   (736,705)  1,608,681   (1,630,038)    (1,911,586)       (64,033)
                           ---------  ----------  -----------  -------------  -------------
Cash flows from financing
 activities:
 Registration fees and
  costs in connection
  with exchange of common
  stock for amounts due
  to Abiomed Limited
  Partnership............    (51,573)        --           --             --             --
 Proceeds from exercise
  of stock options and
  stock purchase plan....     10,205     148,652      545,294        197,415         66,244
                           ---------  ----------  -----------  -------------  -------------
     Net cash (used in)
      provided by
      financing
      activities.........    (41,368)    148,652      545,294        197,415         66,244
                           ---------  ----------  -----------  -------------  -------------
Net increase (decrease)
 in cash and cash
 equivalents, excluding
 investments.............    134,033   2,324,241   (1,321,636)    (1,556,480)       (11,420)
Cash and cash
 equivalents, excluding
 investments, at
 beginning of period.....    480,058     614,091    2,938,332      2,938,332      1,616,696
                           ---------  ----------  -----------  -------------  -------------
Cash and cash
 equivalents, excluding
 investments, at end of
 period..................  $ 614,091  $2,938,332  $ 1,616,696  $   1,381,852  $   1,605,276
                           =========  ==========  ===========  =============  =============

The accompanying notes are an integral part of these consolidated financial statements.

F-6

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

(1) SUMMARY OF OPERATIONS AND SIGNIFICANT ACCOUNTING POLICIES

ABIOMED(R), Inc. and subsidiaries (the Company) is engaged primarily in the research, development and commercialization of medical devices, with a primary focus on the development of cardiac support systems. In particular, the Company markets the BVS-5000(R) system, a bi-ventricular temporary artificial heart, from which the majority of the Company's product revenues have been derived. The accompanying consolidated financial statements reflect the application of certain significant accounting policies described below.

(a) Principles of Consolidation

The accompanying consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries, and beginning in fiscal 1996, the accounts of its majority-owned subsidiary Abiomed Limited Partnership. All significant intercompany accounts and transactions have been eliminated in consolidation.

(b) Uses of Estimates in the Preparation of Financial Statements

The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenue and expenses during the reporting period. Actual results could differ from those estimates.

(c) Interim Financial Statements

The accompanying consolidated financial statements include amounts from interim periods that are unaudited but, in the opinion of management, include all adjustments (consisting only of normal, recurring adjustments) necessary for a fair presentation of results for these interim periods. The results of operations for the three months ended June 30, 1997 are not necessarily indicative of results to be expected for the fiscal year ending March 31, 1998.

(d) Product Revenues

The Company recognizes product revenues at the time products are shipped to the customers. Service revenues, which are not material, are recognized over the periods of the contracts. In fiscal 1995, 1996 and 1997, 13%, 9% and 7%, respectively, of product revenues were from customers located outside of the United States. No customer accounted for greater than 10% of product revenues during fiscal 1995, 1996 or 1997.

(e) Contract Revenues

In fiscal 1995, 1996 and 1997, the majority of the Company's research and development contract revenues were generated from contracts and grants with various government agencies. Each of these contracts and grants provide for revenues on a cost-plus-fixed-fee basis. The Company recognizes revenue under its government contracts and grants as work is performed, provided that the government has appropriated sufficient funds for the work. The Company retains rights to all technological discoveries and products resulting from these efforts. Costs associated with these contracts and grants are recorded in the accompanying consolidated financial statements as part of research and development expenses and totaled approximately $1,718,000, $2,457,000, $3,232,000, $694,000 and $1,513,000 for fiscal 1995, 1996 and 1997, and for the three months ended June 30, 1996 and 1997, respectively.

F-7

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

(f) Inventories

Inventories include raw materials, work-in-process and finished goods, are priced at the lower of cost (first-in, first-out) or market and consist of the following:

                                                  MARCH 31,
                                            ---------------------  JUNE 30,
                                               1996       1997       1997
                                            ---------- ---------- -----------
                                                                  (unaudited)
Raw materials.............................. $  799,548 $  896,433 $1,050,941
Work-in-process............................    428,287    373,383    266,881
Finished goods.............................    425,677    550,967    696,122
                                            ---------- ---------- ----------
                                            $1,653,512 $1,820,783 $2,013,944
                                            ========== ========== ==========

Finished goods and work-in-process inventories consist of direct material, labor and overhead.

(g) Depreciation and Amortization

The Company provides for depreciation and amortization by charges to operations in amounts that allocate the cost of depreciable assets over their estimated useful lives as follows:

                                                                   ESTIMATED
  CLASSIFICATION                          METHOD                  USEFUL LIFE
  --------------                          ------                 -------------
Machinery and equip-
 ment...................  Sum-of-the-year's digits/Straight-line    3- 5 Years
Furniture and fixtures..  Sum-of-the-year's digits/Straight-line    5-10 Years
Leasehold improvements..  Straight-line                          Life of lease

(h) Net Income (Loss) per Common and Common Equivalent Share

Net income per common and common equivalent share is computed by dividing net income by the weighted average number of common and common equivalent shares outstanding during the period using the treasury stock method. Net loss per share is computed by dividing the net loss by the weighted average number of common shares outstanding during the period excluding the effect of stock options outstanding.

(i) Cash and Cash Equivalents

The Company classifies any marketable security with an original maturity date of 90 days or less at the time of purchase as a cash equivalent.

(j) Investments

The Company classifies any security, including marketable securities, with an original maturity of greater than 90 days as investments and classifies investments with a maturity of greater than one year from the balance sheet date as long-term investments.

Under Statement of Financial Accounting Standards (SFAS) No. 115, Accounting for Certain Investments in Debt and Equity Securities, investments that the Company has the positive intent and ability to hold to maturity are reported at amortized cost and classified as held-to-maturity. The Company has classified all investments at March 31, 1996 and 1997 as held-to-maturity. The amortized cost and market value of short-term investments were approximately $7,709,000 and $7,545,000 at March 31, 1996 and $7,745,000 and $7,689,000 at March 31, 1997, respectively. At March 31, 1997, these short-term investments consisted of government grade securities.

F-8

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

(k) Disclosures about Fair Value of Financial Instruments

As of March 31, 1996 and 1997 the Company's financial instruments were comprised of cash and cash equivalents, accounts receivable, accounts payable and short term investments, the carrying amounts of which approximated fair market value.

(l) Recent Accounting Pronouncements

For fiscal 1997, under SFAS No. 121 Accounting for the Impairment of Long- lived Assets and for Long-lived Assets to be Disposed of, the Company is required to review impairment of long-lived assets and certain intangibles whenever events indicate that the carrying amount of the assets may not be recoverable. The adoption of this statement did not have a material impact on the Company's results of operations.

On March 3, 1997, the Financial Accounting Standards Board (FASB) issued SFAS No. 128, Earnings Per Share, superseding Accounting Principles Board (APB) Opinion No. 15. SFAS No. 128 establishes standards for the computation and presentation of earnings per share (EPS) and applies to entities with publicly held common stock or potential common stock. This statement is effective for fiscal years ending after December 15, 1997 and requires restatement of all prior-period EPS data presented. The statement is not expected to have a material impact on the Company's EPS presentation.

(2) CAPITAL STOCK

Each share of Common Stock has a voting right of one vote per share. During fiscal 1996 and 1997 respectively, 612,000 and 1,428,000 shares of Class A Common Stock, representing all of the remaining shares of Class A Common Stock, were converted to Common Stock. As of August 1997, Class A Common Stock is no longer authorized.

The Company has authorized 1,000,000 shares of Class B Preferred Stock, $.01 par value, of which the designation, rights and privileges can be set by the Board of Directors. No share of Class B Preferred Stock has been issued or is outstanding.

On August 13, 1997, the Company declared a dividend of one Preferred Share Purchase Right (the "Right") for each outstanding share of Common Stock to its stockholders of record at August 28, 1997. Each right entitles the registered holder to purchase from the Company one one-thousandth of a share of Series A Junior Participating Preferred Stock with a par value of $0.01 per share, at a price of $90.00 per one one-thousandth of a share, subject to adjustment.

In accordance with the terms set forth in the Rights Agreement, the Rights are not exercisable until the occurrence of certain events, as defined. In addition, the registered holders of the Rights will have no rights as a Common stockholder of the Company until the Rights are exercised. The terms of the Rights may be amended by the Board of Directors. The Rights will expire on August 13, 2007.

(3) LINE OF CREDIT WITH A BANK

The Company has an unsecured demand line of credit under which it can borrow up to $3,000,000 from a bank at the bank's prime rate. The Company is required to maintain a compensating balance of $100,000 plus 5% of any amounts outstanding under the arrangement. There were no borrowings under the company's line of credit at March 31, 1996 and 1997 and June 30, 1997. The Company has renewed this line of credit in each of the past three years. The current line of credit expires in September 1998.

F-9

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

(4) INCOME TAXES

The Company accounts for income taxes in accordance with the provisions of SFAS No. 109, Accounting for Income Taxes. The asset and liability approach used under SFAS No. 109 requires a recognition of deferred tax assets and liabilities for the expected future tax consequences of temporary differences between the carrying amounts and the tax bases of other assets and liabilities.

At March 31, 1997 the Company had available net operating loss carryforwards of approximately $21,241,000. The Company also had available, at March 31, 1997, approximately $766,000 of tax credits to reduce future federal income taxes, if any. The net operating loss and tax credit carryforwards expire through 2010. These carryforwards are subject to review by the Internal Revenue Service and may be subject to limitation in any given year under certain conditions.

During 1997, the Company utilized a portion of its net operating loss carryforward to reduce its current year taxable income. The Company has placed a valuation allowance of approximately $11,330,000 as of March 31, 1997 against its otherwise recognizable net deferred tax asset due to the uncertainty surrounding the timing of the realization of the tax benefits.

The deferred tax asset as of March 31, 1996 and 1997 consisted of the following:

                                                         MARCH 31,
                                                 --------------------------
                                                     1996          1997
                                                 ------------  ------------
Purchase of technology (Note 7)................. $  1,573,000  $  1,353,000
Net operating loss and tax credit
 carryforwards..................................    9,082,000     9,262,000
Other, net......................................      549,000       715,000
                                                 ------------  ------------
                                                   11,204,000    11,330,000
Less--Valuation allowance.......................  (11,204,000)  (11,330,000)
                                                 ------------  ------------
                                                 $        --   $        --
                                                 ============  ============

(5) COMMITMENTS

(a) The Company leases its facilities and certain equipment under various operating lease agreements with terms through fiscal 2001. Total rent expense under these leases, included in the accompanying consolidated statements of operations, was approximately $262,000, $233,000 and $324,000 for fiscal 1995, 1996 and 1997, respectively.

Future minimum lease payments under these agreements are as follows:

YEARS ENDED MARCH 31,                                               AMOUNT
---------------------                                              --------
  1998............................................................ $307,000
  1999............................................................  247,000
  2000............................................................  120,000
  2001............................................................   31,000
                                                                   --------
                                                                   $705,000
                                                                   ========

F-10

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

(b) The Company maintains various insurance coverages. Most policies renew on a fiscal year basis while several policies have been secured for a three- year period. Future insurance obligations under these insurance policies, over a three-year period, are approximately $540,000.

(6) STOCK OPTIONS PLANS

All stock options granted by the Company under the plans described below were granted at the fair value of the stock at the date of grant. Outstanding stock options, if not exercised, expire 10 years from the date of grant.

The 1992 Combination Stock Option Plan (the Combination Plan) as amended, approved by the Company's stockholders, combined and restated the Company's then outstanding Incentive Stock Option Plan and Nonqualified Plan. The options generally become exercisable ratably over five years. All of the options granted under the Combination Plan during the three years ended March 31, 1997 were to employees.

In addition, the Company has a nonqualified stock option plan for nonemployee directors (the Directors' Plan). The Directors' Plan, as adopted in July 1989 and amended, with shareholder approval, granted options to purchase 12,500 shares of the Company's Common Stock to each of the Company's then elected outside directors and provides for grants of options to purchase 12,500 shares of the Company's Common Stock to any newly elected eligible director. Thereafter, each eligible director will be granted a new option to purchase 12,500 shares of Common Stock on July 1 of each successive fifth year. These options vest over a five-year period at the rate of 2,500 shares per year, commencing on June 30 of the year following the date of grant.

F-11

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

The following table summarizes stock option activity under these plans:

                                 COMBINATION PLAN                  DIRECTORS' PLAN
                         --------------------------------- ---------------------------------
                                                 WEIGHTED                          WEIGHTED
                         NUMBER                   AVERAGE  NUMBER                   AVERAGE
                           OF                      PRICE     OF                      PRICE
                         OPTIONS  EXERCISE PRICE PER SHARE OPTIONS  EXERCISE PRICE PER SHARE
                         -------  -------------- --------- -------  -------------- ---------
Options outstanding,
 March 31, 1994......... 410,830  $ 0.55-$13.50   $ 8.47    95,000  $ 7.00-$13.88   $10.72
 Options granted........  17,000     5.63- 6.50     6.19       --             --       --
 Options exercised......  (1,100)          5.75     5.75       --             --       --
 Options canceled....... (31,500)   5.75- 13.50     8.48       --             --       --
                         -------  -------------   ------   -------  -------------   ------
Options outstanding,
 March 31, 1995......... 395,230     0.55-13.50     8.38    95,000     7.00-13.88   $10.72
 Options granted........ 219,000     6.25-11.00    10.23    12,500          11.00    11.00
 Options exercised...... (16,925)    5.75- 8.50     7.34    (2,500)          7.00     7.00
 Options canceled....... (19,140)    5.75-13.50     9.90   (15,000)   11.00-11.13    11.02
                         -------  -------------   ------   -------  -------------   ------
Options outstanding,
 March 31, 1996......... 578,165     0.55-13.50   $ 9.09    90,000     7.00-13.88    10.81
 Option granted......... 234,235    11.00-13.50    12.53       --             --       --
 Options exercised...... (59,112)    0.55-13.50     8.65       --             --       --
 Options canceled....... (55,413)    5.75-13.50    11.45       --             --       --
                         -------  -------------   ------   -------  -------------   ------
Options outstanding,
 March 31, 1997......... 697,875  $ 5.63-$13.50   $10.29    90,000  $ 7.00-$13.88   $10.81
 Option granted......... 141,500    10.00-12.75    11.09       --             --       --
 Options exercised......  (9,590)    5.75- 8.00     6.91       --             --       --
 Options canceled.......    (600)          8.00     8.00       --             --       --
                         -------  -------------   ------   -------  -------------   ------
Options outstanding,
 June 30, 1997.......... 829,185  $ 5.63-$13.50   $10.53    90,000  $ 7.00-$13.88   $10.81
                         =======                           =======
Options exercisable:
 March 31, 1997......... 179,415  $ 5.63-$13.50    $8.96    70,000  $ 7.00-$13.88   $10.76
                         =======                           =======
 June 30, 1997.......... 181,225  $ 5.63-$13.50    $9.02    70,000  $ 7.00-$13.88   $10.76
                         =======                           =======
Shares available for
 Future issuance,
 March 31, 1997......... 459,032                           107,500
                         =======                           =======
 June 30, 1997.......... 318,132                           107,500
                         =======                           =======

The Company has an Employee Stock Purchase Plan (the Purchase Plan), as amended. Under the Purchase Plan, all employees (including officers and directors) of the Company who have completed six months of employment are eligible to purchase the Company's Common Stock at an exercise price equal to 85% of the fair market value of the Common Stock. The Company has reserved 100,000 shares of Common Stock for issuance under the Purchase Plan, of which 90,718 shares are available for future issuance as of March 31, 1997. During the years ended March 31, 1996 and 1997, 777 shares and 1,116 shares, respectively, of Common Stock were sold pursuant to the Purchase Plan.

F-12

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

In October 1995, FASB issued SFAS No. 123, Accounting for Stock-Based Compensation. SFAS No. 123 requires the measurement of the fair value of stock options, including stock purchase plans, or warrants granted to employees to be included in the statement of operations or disclosed in the notes to financial statements. The Company has determined that it will continue to account for stock-based compensation for employees under APB Opinion No. 25 and elect the disclosure-only alternative under SFAS No 123. The Company has computed the pro forma disclosures required under SFAS No. 123 for options granted in fiscal 1996 and 1997 using the Black-Scholes option pricing model prescribed by SFAS No. 123. The weighted average information and assumptions used for 1996 and 1997 are as follows:

                                                           1996     1997
                                                          -------  -------
Risk-free interest rate..................................    6.75%    6.75%
Expected dividend yield..................................     --       --
Expected life............................................ 5 years  5 years
Expected volatility......................................      30%      33%

The Black-Scholes option-pricing model was developed for use in estimating the fair value of traded options, which have no vesting restrictions and are fully transferable. In addition, option-pricing models require the input of highly subjective assumptions including expected stock price volatility. Because the Company's employee stock options have characteristics significantly different from those of traded options, and because changes in the subjective input assumptions can materially affect the fair value estimate, in management's opinion, the existing models do not necessarily provide a reliable single measure of the fair value of its employee stock options.

The total fair value of the options granted during fiscal 1996 and 1997 was computed as approximately $431,000 and $598,000, respectively. Of these amounts approximately $108,000 and $257,000 would be charged to operations for the years ended March 31, 1996 and 1997 respectively. The remaining amount, approximately $664,000, would be amortized over the remaining vesting periods. Similarly, the total fair value of stock sold under this Purchase Plan was computed as approximately $4,000 and $3,000 during fiscal 1996 and 1997. The resulting pro forma compensation expense may not be representative of the amount to be expected in future years as pro forma compensation expense may vary based upon the number of options granted and shares purchased.

The pro forma net income and pro forma net income per common share presented below have been computed assuming no tax benefit. The effect of a tax benefit has not been considered since a substantial portion of the stock options granted are incentive stock options and the Company does not anticipate a future deduction associated with the exercise of these stock options.

The pro forma effect of SFAS No. 123 for the years ended March 31, 1996 and 1997 is as follows:

                                         1996                  1997
                                 --------------------- ---------------------
                                 AS REPORTED PRO FORMA AS REPORTED PRO FORMA
                                 ----------- --------- ----------- ---------
Net income.....................   $491,124   $379,124   $735,264   $475,264
Pro forma net income per common
 and common equivalent share...   $  0 .07   $  0 .05   $  0 .10   $  0 .07

(7) ROYALTY OBLIGATION

Commencing April 1, 1995 and ending August 3, 2000, the Company owes a royalty to certain third parties equal in aggregate to approximately 2.1% of certain revenues derived from the BVS 5000 and certain

F-13

ABIOMED, INC. AND SUBSIDIARIES

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS--(CONTINUED)

MARCH 31, 1997 AND JUNE 30, 1997 (UNAUDITED)

other technology incorporated in the SupraCor(R). This royalty is subject to certain maximum revenue amounts and to certain adjustments, as defined, in the event that the Company sells the underlying technology. For the years ended March 31, 1996 and 1997, the amount of this royalty, net of certain reimbursed expenses, was approximately $160,000 and $216,000, respectively. These amounts are reflected as part of the cost of product sales in the accompanying consolidated financial statements.

This royalty is paid to the third parties through Abiomed Limited Partnership which, at present, is inactive except with respect to the distribution of such royalties. During fiscal 1996, the Company paid $770,000 to reduce its royalty obligation to 2.1%, as described above. This one-time payment capitalized by the Company, is being amortized on a straight-line basis over the estimated useful life of the asset (5 years) and, net of accumulated amortization, is classified as a long-term other asset in the accompanying consolidated financial statements.

(8) EMPLOYEE DEFERRED COMPENSATION PROFIT-SHARING PLAN AND TRUST

The Company has an Employee Deferred Compensation Profit-sharing Plan and Trust (the 401(k) Plan) that covers all employees over 20 years of age who have completed at least six months of service with the Company. Contributions by the Company are determined by the Company's Board of Directors and totaled approximately $36,000, $80,000 and $59,000 for the fiscal years ended March 31, 1995, 1996 and 1997, respectively.

(9) ACCRUED EXPENSES

Accrued expenses consist of the following:

                                                 MARCH 31,
                                           ---------------------  JUNE 30,
                                              1996       1997       1997
                                           ---------- ---------- -----------
                                                                 (unaudited)
Salaries and benefits..................... $  703,478 $  700,570 $  942,881
Legal and audit...........................     72,436     76,914     60,691
Customer advances.........................     56,067    287,882    357,508
Sales taxes...............................    214,521    172,836    207,493
Warranty..................................     72,662    227,093    210,354
Other.....................................    367,817    567,211    557,104
                                           ---------- ---------- ----------
                                           $1,486,981 $2,032,506 $2,336,031
                                           ========== ========== ==========

(10) PRO FORMA INFORMATION (UNAUDITED)

On July 15, 1997, the Company completed a private placement of 1,242,710 shares of its Common Stock. Proceeds to the Company from the private placement, net of approximately $145,000 in direct transaction related expenses, totaled approximately $16,010,000. The Company's unaudited pro forma consolidated balance sheet at June 30, 1997 and pro forma statement of stockholders' investment for the three months ended June 30, 1997 has been prepared to give effect to this private placement as if it had occurred on June 30, 1997, and reflects the increases in common stock, at par value of $12,427, additional paid-in capital of $15,997,464, cash of approximately $16,138,000 (net of approximately $17,000 in transaction related expenses) and accounts payable of approximately $128,000 for the remainder of the transaction related expenses.

F-14

[DRAWING OF A TAH IMPLANTED          THE COMPANY'S TOTAL ARTIFICIAL HEART IS
IN A WOMAN]                          A CLASS III DEVICE UNDER DEVELOPMENT AND
                                     HAS NOT BEEN APPROVED FOR SALE IN ANY
                                     COUNTRY. THE COMPANY DOES NOT INTEND TO
                                     APPLY FOR REGULATORY APPROVAL TO MARKET
                                     THIS DEVICE FOR SEVERAL YEARS, IF EVER,
                                     AND WILL BE REQUIRED TO SUCCESSFULLY
                                     COMPLETE CLINICAL TRIALS TO DEMONSTRATE
                                     ITS SAFETY AND EFFICACY PRIOR TO FILING
                                     FOR REGULATORY APPROVAL. SEE "RISK
                                     FACTORS."



[ILLUSTRATION OF THE IMPLANTABLE     Illustration of the
COMPONENTS]                          implantable components of the
                                     TAH. The TAH is a battery-
                                     powered totally implantable
                                     artificial heart being
                                     developed as a permanent
                                     replacement device to assume
                                     the full pumping function of
                                     both the left and right
                                     ventricles of the heart.



    Developmental model of TAH              [PICTURE OF TAH SYSTEM DESCRIBED
    thoracic unit shown next to a           IN CAPTION]
    diseased natural heart.


[ABIOMED LOGO APPEARS HERE]


PART II

INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14. OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

SEC Registration Fee................................................... $14,323
NASD Filing Fee........................................................  30,500
Nasdaq National Market Listing Fee.....................................  17,500
Transfer Agent and Registrant Fees.....................................   2,500*
Accounting Fees and Expenses...........................................  50,000*
Legal Fees and Expenses................................................ 175,000*
Printing and Engraving ................................................  60,000*
Miscellaneous..........................................................  50,177*
                                                                        -------
  TOTAL................................................................ 400,000*
                                                                        =======


* Estimated

ITEM 15. INDEMNIFICATION OF DIRECTORS AND OFFICERS

The Company's Certificate of Incorporation provides that, to the fullest extent permitted by Delaware law, no director of the Company shall be personally liable to the Company or its stockholders for monetary damages for breach of fiduciary duty as a director, notwithstanding any other provision of law. However, a director shall be liable to the extent required by law (i) for any breach of the director's duty of loyalty to the Company or its stockholders, (ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii) in respect of certain unlawful dividend payments or stock redemptions or repurchases, or
(iv) for any transaction from which the director derived an improper personal benefit.

The Company entered into indemnification agreements with each of its directors and anticipates that it will enter into similar agreements with any future director. Generally, these agreements attempt to provide the maximum protection permitted by Delaware law with respect to indemnification. The indemnification agreements provide that the Company will pay certain amounts incurred by a director in connection with any civil or criminal action or proceeding, specifically including actions by or in the name of the Company (derivative suits) where the individual's involvement is by reason of the fact that he is or was a director or officer. For directors, such amounts include, to the maximum extent permitted by law, attorney's fees, judgments, civil or criminal fines, settlement amounts and other expenses customarily incurred in connection with legal proceedings. Under the indemnification agreements, a director will not receive indemnification if the director is found not to have acted in good faith and in a manner he reasonably believed to be in or not opposed to the best interests of the Company. The Company has also entered into similar agreements with certain of the Company's officers and top management personnel who are not also directors. The indemnification agreements with officers are slightly more restrictive. Generally, the indemnification agreements attempt to provide the maximum protection permitted by Delaware law with respect to indemnification of directors and officers.

The effect of these provisions would be to permit such indemnification by the Company for liabilities arising under the Securities Act of 1933, as amended.

Reference is hereby made to Section 8 of the Underwriting Agreement among the Company, the Selling Stockholders and the Underwriters, filed as Exhibit 1.1 to this Registration Statement, for a description of indemnification arrangements among the Company, the Selling Stockholders and the Underwriters.

Reference is hereby made to Section 2 of the Selling Stockholder Agreement among the Company and the Selling Stockholders, filed as Exhibit 99.1 to this Registration Statement, for a description of indemnification arrangements among the Company and the Selling Stockholders.

II-1


ITEM 16. EXHIBITS

EXHIBIT
NUMBER
-------
 1.1    Form of Underwriting Agreement***
 3.1    Restated Certificate of Incorporation of the Company**
 3.2    Restated Bylaws of the Company--Filed as Exhibit 3(b) to the
        Company's Annual Report on Form 10-K for the fiscal year ended
        March 31, 1991*
        Certificate of Designations of Series A Junior Participating
 3.3    Preferred Stock**
 4.1    Specimen Certificate of Common Stock--Filed as Exhibit 4.1 to
        Registration Statement No. 33-14861 on Form S-1*
 4.2    Description of Capital Stock (contained in the Restated
        Certificate of Incorporation of the Company filed as Exhibit 3.1
        and in the Certificate of Designations of Series A Junior
        Participating Preferred Stock filed as Exhibit 3.3)**
 4.3    Rights Agreement between the Registrant and BankBoston, N.A., as
        Rights Agent dated as of August 13, 1997 (including Form of
        Right Certificate attached thereto as Exhibit A)--Filed as
        Exhibit 4 to the Registrant's Current Report on Form 8-K, dated
        August 13, 1997*
 5.1    Legal Opinion of Brown, Rudnick, Freed & Gesmer**
23.1    Consent of Arthur Andersen LLP**
        Consent of Brown, Rudnick, Freed & Gesmer (included in Exhibit
23.2    5.1)**
        Power of Attorney (included on the signature page of this
24.1    Registration Statement)**
99.1    Selling Stockholder Agreement***
99.2    Common Stock Purchase Agreement between the Company and Genzyme
        Corporation**
99.3    Common Stock Purchase Agreements between the Company and certain
        directors**


* Not filed herewith. In accordance with Rule 411 promulgated pursuant to the Securities Act of 1933, as amended, reference is made to the documents previously filed with the Commission, which are incorporated by reference herein. ** Filed herewith. *** To be filed by amendment.

ITEM 17. UNDERTAKINGS

(a) Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the Registrant pursuant to the Registrants By-Laws, or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Act and is, therefore, unenforceable. In the event

II-2


that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue.

(b) The undersigned Registrant hereby further undertakes that:

(1) For purposes of determining any liability under the Securities Act of 1933, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be initial bona fide offering thereof.

(2) For purposes of determining any liability under the Securities Act of 1933, the information omitted from the form of prospectus filed as part of this registration statement in reliance upon Rule 430A and contained in a form of prospectus filed by the Registrant pursuant to Rule 424(b)(1) or
(4) or 497(h) under the Securities Act shall be deemed to be part of this registration statement as of the time it was declared effective.

(3) For the purpose of determining any liability under the Securities Act of 1933, each post-effective amendment that contains a form of prospectus shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

II-3


SIGNATURES

PURSUANT TO THE REQUIREMENTS OF THE SECURITIES ACT OF 1933, THE REGISTRANT CERTIFIES THAT IT HAS REASONABLE GROUNDS TO BELIEVE THAT IT MEETS ALL OF THE REQUIREMENTS FOR FILING ON FORM S-3 AND HAS DULY CAUSED THIS REGISTRATION STATEMENT TO BE SIGNED ON ITS BEHALF BY THE UNDERSIGNED, THEREUNTO DULY AUTHORIZED, IN THE CITY OF BOSTON, COMMONWEALTH OF MASSACHUSETTS, ON SEPTEMBER 29, 1997.

ABIOMED, Inc.

       /s/ Dr. David M. Lederman
By: _________________________________
  DR. DAVID M. LEDERMANPRESIDENT AND
        CHIEF EXECUTIVE OFFICER

POWER OF ATTORNEY

KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Dr. David M. Lederman and John F. Thero his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any or all amendments (including post-effective amendments) to this Registration Statement, and to file the same, with all exhibits thereto and other documents in connection therewith, and, in connection with any registration of additional securities pursuant to Rule 462(b) under the Securities Act of 1933, as amended, to sign any abbreviated registration statement and any and all amendments thereto, and to file the same, with all exhibits thereto and other documents in connection therewith, in each case, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys- in-fact and agents, or any of them, or their substitutes, may lawfully do or cause to be done by virtue hereof.

PURSUANT TO THE REQUIREMENTS OF THE SECURITIES ACT OF 1933, THIS REGISTRATION STATEMENT HAS BEEN SIGNED BY THE FOLLOWING PERSONS IN THE CAPACITIES AND ON THE DATES INDICATED.

              SIGNATURE                        TITLE                 DATE

        /s/ David M. Lederman          Chief Executive          September 29,
-------------------------------------   Officer, President           1997
          DAVID M. LEDERMAN             and Director
                                        (Principal
                                        Executive Officer)

          /s/ John F. Thero            Chief Financial          September 29,
-------------------------------------   Officer, Vice                1997
            JOHN F. THERO               President--Finance
                                        and Treasurer
                                        (Principal Financial
                                        and Accounting
                                        Officer)

                                     II-4

              SIGNATURE                         TITLE                DATE

    /s/ Desmond H. O'Connell, Jr.       Director                September 29,
-------------------------------------                                1997
      DESMOND H. O'CONNELL, JR.

                                        Director                 September  ,
-------------------------------------                                1997
           JOHN F. O'BRIEN

        /s/ Henri A. Termeer            Director                September 29,
-------------------------------------                                1997
          HENRI A. TERMEER

        /s/ W. Gerald Austen            Director                September 29,
-------------------------------------                                1997
          W. GERALD AUSTEN

          /s/ Paul Fireman              Director                September 29,
-------------------------------------                                1997
            PAUL FIREMAN

II-5


EXHIBIT INDEX

EXHIBIT
NUMBER  DESCRIPTION
------- -----------
 1.1    Form of Underwriting Agreement***
 3.1    Restated Certificate of Incorporation of the Company**
 3.2    Restated Bylaws of the Company--Filed as Exhibit 3(b) to the Company's
        Annual Report on Form 10-K for the fiscal year ended March 31, 1991*
        Certificate of Designations of Series A Junior Participating Preferred
 3.3    Stock**
 4.1    Specimen Certificate of Common Stock--Filed as Exhibit 4.1 to
        Registration Statement No. 33-14861 on Form S-1*
 4.2    Description of Capital Stock (contained in the Restated Certificate of
        Incorporation of the Company filed as Exhibit 3.1 and in the
        Certificate of Designations of Series A Junior Participating Preferred
        Stock filed as Exhibit 3.3)**
 4.3    Rights Agreement between the Registrant and BankBoston, N.A., as
        Rights Agent dated as of August 13, 1997 (including Form of Right
        Certificate attached thereto as Exhibit A)--Filed as Exhibit 4 to the
        Registrant's Current Report on Form 8-K, dated August 13, 1997*
 5.1    Legal Opinion of Brown, Rudnick, Freed & Gesmer**
23.1    Consent of Arthur Andersen LLP**
23.2    Consent of Brown, Rudnick, Freed & Gesmer (included in Exhibit 5.1)**
        Power of Attorney (included on the signature page of this Registration
24.1    Statement)**
99.1    Selling Stockholder Agreement***
99.2    Common Stock Purchase Agreement between the Company and Genzyme
        Corporation**
99.3    Common Stock Purchase Agreements between the Company and certain
        directors**


* Not filed herewith. In accordance with Rule 411 promulgated pursuant to the Securities Act of 1933, as amended, reference is made to the documents previously filed with the Commission, which are incorporated by reference herein. ** Filed herewith.

*** To be filed by amendment.


EXHIBIT 3.1

PAGE 1
State of Delaware

OFFICE OF THE SECRETARY OF STATE


I, EDWARD J. FREEL, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO HEREBY CERTIFY THE ATTACHED IS A TRUE AND CORRECT COPY OF THE RESTATED CERTIFICATE OF "ABIOMED, INC.", FILED IN THIS OFFICE ON THE FOURTEENTH DAY OF AUGUST, A.D.
1997, AT 2:17 O'CLOCK P.M.

A CERTIFIED COPY OF THIS CERTIFICATE HAS BEEN FORWARDED TO THE NEW CASTLE

COUNTY RECORDER OF DEEDS FOR RECORDING.

[STAMP]        /s/ Edward J. Freel
              ----------------------------------------
              Edward J. Freel, Secretary of State

              AUTHENTICATION:     8607146

                        DATE:     08-14-97


RESTATED CERTIFICATE OF INCORPORATION

OF

ABIOMED, Inc.

ABIOMED, INC., a corporation organized and existing under the laws of the State of Delaware (the "Corporation"), pursuant to Section 245 of the Delaware General Corporation Law, hereby certifies as follows:

A. The original certificate of incorporation of the Corporation was filed with the Secretary of State of Delaware on June 4, 1987.

B. This Restated Certificate of Incorporation only restates and integrates and does not further amend the provisions of the Corporation's certificate of incorporation, as heretofore amended or supplemented (the "Original Certificate of Incorporation"), and there is no discrepancy between those provisions and the provisions of this Restated Certificate of Incorporation within the meaning of
Section 245(c) of the General Corporation Law of the State of Delaware. As permitted under said Section 245(c), this Amended and Restated Certificate omits
(a) such provisions of the Original Certificate of Incorporation which named the incorporator and the initial board of directors, and (b) such provisions contained in the Original Certificate of Incorporation as were necessary to effect a cancellation of the Corporation's Class A Common Stock and Class A Preferred Stock, which cancellation has become effective pursuant to the terms of the Original Certificate of Incorporation.

C. This Amended and Restated Certificate of Incorporation was approved by the Board of Directors of the Corporation at a meeting held on August 13, 1997, in accordance with Section 245 of the General Corporation Law of the State of Delaware.

D. The text of the certificate of incorporation of the Corporation, as restated herein, shall read in its entirety as follows:

1. NAME. The name of the corporation is ABIOMED, Inc.

2. REGISTERED OFFICE. The address, including street, number, city, and county, of the registered office of the corporation in the State of Delaware is c/o The Prentice-Hall Corporation System, Inc., 1013 Centre Road, City of Wilmington, County of New Castle, Delaware 19805; and the name of the registered agent of the corporation in the State of Delaware at such address is The Prentice-Hall Corporation System, Inc.

3. PURPOSE. The nature of the business and the purposes to be conducted and promoted by the corporation shall be (a) to engage in the research, development, manufacturing, marketing and sale of medical and biomedical devices and instrumentation and medical products, and (b) any lawful business, to promote any lawful purpose, and to engage in any lawful act or activity for which corporations may be organized under the Delaware General Corporation Law.

4. CAPITAL STOCK. A statement of the designations and powers, preferences and rights, and the qualifications, limitations or restrictions of the classes of capital stock of the corporation shall be as follows:

PART 4.1 - DESIGNATION AND NUMBERS.

The total number of shares of capital stock which the corporation shall have authority to issue shall be divided into two classes as follows:

(i) 25,000,000 shares of Common Stock, par value $.01 per share;

(ii) 1,000,000 shares of Class B Preferred Stock, par value $.01 per share.

PART 4.2 - COMMON STOCK

4.2.1. Dividends and Other Distributions. Subject to the limitations, if any, prescribed in the provisions of any class or series of stock having a preference over the Common Stock, holders of shares of Common Stock shall be entitled to receive, when and as declared by the board of directors out of the assets or funds of the corporation which are by law available therefor, dividends payable in cash or in property or in any combination thereof.

4.2.2. Voting Rights and Powers.

(a) Except as otherwise required by law, with respect to all matters upon which stockholders are entitled to vote or give consent, the holders of the outstanding shares of the Common Stock shall be entitled to cast thereon one (1) vote in person or by proxy for each share of the Common Stock standing in his or her name. No action required to be taken or which may be taken at any annual or special meeting of stockholders of the Corporation may be taken by stockholders without a meeting, and the power of stockholders to consent in writing, without a meeting, to the taking of any action is specifically denied.

(b) Any director elected by the holders of Common Stock voting as a separate class may only be removed for cause by the holders of the Common Stock voting as a separate class. The remaining directors may be removed only for cause by the stockholders who are entitled to elect the director.

(c) Any vacancy in the office of director shall be filled by the remaining directors, and in the absence of any directors, by the stockholders.

(d) This Section 4.2.2 shall not be amended, altered or repealed except by the affirmative vote of eighty percent (80%) of the votes entitled to be cast by the stockholders.

4.2.3. Liquidation. In the event the corporation shall be liquidated, dissolved or wound up, whether voluntarily or involuntarily, after there shall have been paid or set aside the full preferential amounts to which the holders of any class or series having a preference over the Common Stock are entitled, the holders of Common Stock shall be entitled to share in the remaining net assets of the corporation. A merger or consolidation of the corporation with or into any other corporation or a sale or conveyance of all or any part of the assets of the corporation which shall not in fact result in the liquidation of the corporation and the distribution of assets to stockholders shall not be deemed to be a voluntary or involuntary liquidation or dissolution or winding up of the corporation within the meaning of this Section 4.2.3.

PART 4.3 - CLASS B PREFERRED STOCK

4.3.1. General. The Class B Preferred Stock may consist of one or more series. The Board of Directors may, from time to time, establish and designate the different series and the variations in the preferences and relative, participating, optional or other special rights, and

qualifications, limitations or restrictions as between the different series provided in Section 4.3.2 hereof, but in all other respects all shares of the Class B Preferred Stock shall be identical. In the event that at any time the Board of Directors shall have established and designated one or more series of Class B Preferred Stock consisting of a number of shares less than all of the authorized number of shares of Class B Preferred Stock, the remaining authorized shares of Class B Preferred Stock shall be deemed to be shares of an undesignated series of Class B Preferred Stock until designated by the Board of Directors as being a part of a series previously established or a new series then being established by the Board of Directors.

4.3.2. Establishment of a Series. Subject to the provisions of this Article Fourth, the Board of Directors is authorized to establish one or more series of Class B Preferred Stock and, to the extent now or hereafter permitted by the laws of the State of Delaware, to fix and determine the preferences and relative, participating, optional or other special rights, and qualifications, limitations or restrictions of each series, including, but not limited to:

(a) the number of shares to constitute such series and the distinctive designation such series;

(b) the dividend rate on the shares of such series and preferences, if any, and the special and relative rights of such shares of such series as to dividends;

(c) whether or not the shares of such series shall be redeemable, and, if redeemable, the price, terms and manner of redemption;

(d) the preferences, if any, and the special and relative rights of the shares of such series upon liquidation of the corporation;

(e) whether or not the shares of such series shall be subject to the operation of a sinking or purchase fund and, if so, the terms and provisions of such fund;

(f) whether or not the shares of such series shall be convertible into shares of any other class or of any other series of the same or any other class of stock of the corporation and, if so, the conversion price or ratio and other conversion rights;

(g) the conditions under which the shares of such series shall have separate voting rights or no voting rights; and

(h) such other designations, preferences and relative, participating, optional or other special rights and qualifications, limitations or restrictions of such series to the full extent now and hereafter permitted by the laws of the State of Delaware.

Notwithstanding the fixing of the number of shares constituting a particular series, the Board of Directors may at any time thereafter by resolution authorize the increase or decrease in the number of shares of the same series, subject to the limitations of Section 151(g) of the Delaware General Corporation Law.

4.3.3. Dividends. Holders of Class B Preferred Stock shall be entitled to receive, when, if and as declared by the Board of Directors, but only out of funds legally available for the payment of dividends, cash dividends at the rates fixed by the Board of Directors for the respective series, payable on such dates in each year as the Board of Directors shall fix for the respective series as provided in Section 4.3.2 (hereinafter referred to as "dividend dates"). Until all accrued dividends on each series of Class B Preferred Stock shall have been paid through the

last preceding dividend date of each such series, no dividend or distribution shall be made to holders of Common Stock other than a dividend payable in Common Stock of the corporation. Dividends on shares of any cumulative series of Class B Preferred Stock shall accumulate from and after the day on which such shares are issued, but arrearages in the payment thereof shall not bear interest. Nothing hereincontained shall be deemed to limit the right of the corporation to purchase or otherwise acquire at any time any shares of its capital stock.

For purposes of this Part 4.3 the amount of dividends "accrued" on any shares of any cumulative series of Class B Preferred Stock as at any dividend date shall be deemed to be the amount of any unpaid dividends accumulated thereon to and including such dividend date, whether or not earned or declared. The amount of dividends "accrued" on any noncumulative series of Class B Preferred Stock shall mean only those dividends declared by the Board of Directors, unless otherwise specified for such series by the Board of Directors pursuant to Section 4.3.2.

4.3.4. Liquidation. Upon the voluntary or involuntary liquidation of the corporation, before any payment or distribution of the assets of the corporation shall be made to or set apart for any other class of stock, the holders of Class B Preferred Stock shall be entitled to payment of the amount of the preference payable upon such liquidation of the corporation fixed by the Board of Directors for the respective series as provided in Section 4.3.2. If, upon any such liquidation, the assets of the corporation shall be insufficient to pay in full to the holders of the Class B Preferred Stock the preferential amount aforesaid, then such assets, or the proceeds thereof, shall be distributed among the holders of each series of Class B Preferred Stock ratably in accordance with the sums which would be payable on such distribution if all sums payable were discharged in full. The voluntary sale, conveyance, exchange or transfer of all or substantially all of the property and assets of the corporation, the merger or consolidation of the corporation into or with any other corporation, or the merger of any other corporation into it, shall not be deemed to be a liquidation of the corporation for the purpose of this Section 4.3.4.

4.3.5. Retirement. Any shares of Class B Preferred Stock which shall at any time have been redeemed, or which shall at any time have been surrendered for conversion or exchange or for cancellation pursuant to any sinking or purchase fund provisions with respect to any series of Class B Preferred Stock, shall be retired and shall thereafter have the status of authorized and unissued shares of Class B Preferred Stock undesignated as to series.

4.3.6. Voting Rights. The Board of Directors shall, at the time any series of Class B Preferred Stock is established, determine whether or not the shares of such series shall be entitled to vote. The Board of Directors, in establishing a series of Class B Preferred Stock and fixing the voting rights thereof, may determine that the voting power of each share of such series may be greater or less than the voting power of each share of the Common Stock or of other series of Class B Preferred Stock notwithstanding that the shares of such series of Class B Preferred Stock may vote as a single class with the shares of other series of Class B Preferred Stock and/or with the shares of Common Stock.

5. EXISTENCE. The corporation shall have perpetual existence.

6. CERTAIN SETTLEMENTS. Whenever a compromise or arrangement is proposed between this corporation and its creditors or any class of them and/or between this corporation and its stockholders or any class of them, any court of equitable jurisdiction within the State of Delaware may, on the application in a summary way of this corporation or of any creditor or stockholder thereof or on the application of any receiver or receivers appointed for this corporation under the provisions of Section 291 of Title 8 of the Delaware Code or on the

application of trustees in dissolution or of any receiver or receivers appointed for this corporation under the provisions of Section 279 of Title 8 of the Delaware Code order a meeting of the creditors or class of creditors, and/or of the stockholders or class of stockholders of this corporation, as the case may be, to be summoned in such manner as the said court directs. If a majority in number representing three-fourths in value of the creditors or class of creditors, and/or of the creditors or class of creditors, and/or of the stockholders or class of stockholders of this corporation, as the case may be, agree to any compromise or arrangement,the said compromise or agreement and the said reorganization shall, if sanctioned by the court to which the said application has been made, be binding on all class of creditors, and/or on the stockholders, of this corporation, as the case may be, and also on this corporation.

7. POWERS OF DIRECTORS. For the management of the business and for the conduct of the affairs of the corporation, and in further definition, limitation and regulation of the powers of the corporation and of its directors and of its stockholders or any class thereof, as the case may be, it is further provided that:

a. The business of the corporation shall be conducted by the officers of the corporation under the supervision of the Board of Directors.

b. The number of directors which shall constitute the whole Board of Directors shall be fixed by, or in the manner provided in, the By-Laws. No election of Directors need be by written ballot.

c. The Board of Directors of the corporation may adopt, amend or repeal the By-Laws of the corporation at any time after the original adoption of the By-Laws according to Section 109 of the Delaware General Corporation Law; provided, however, that any amendment to provide for the classification of Directors of the corporation for staggered terms pursuant to the provisions of subsection (d) of Section 141 of the Delaware General Corporation Law shall be set forth in an amendment to this Certificate of Incorporation, in an initial By-Law, or in a By-Law adopted by the stockholders of the corporation entitled to vote.

8. LIMITATION OF LIABILITY. No director shall be personally liable to the corporation or its stockholders for monetary damages for any breach of fiduciary duty by such director as a director, notwithstanding any other provision of law to the contrary. However, a director shall be liable to the extent required by applicable law (i) for breach of the director's duty of loyalty to the corporation or its stockholders, (ii) for acts or omissions not in good faith or which involve intentional misconduct or a knowing violation of law, (iii) pursuant to Section 174 of the Delaware General Corporation Law or (iv) for any transaction from which the director derived an improper personal benefit. No amendment to or repeal of this Article 8 shall deprive a director of the benefits hereof with respect to any acts or omissions of such director occurring prior to such amendment or repeal.

9. INDEMNIFICATION. The corporation may, to the fullest extent permitted by Section 145 of the Delaware General Corporation Law, as the same may be amended and supplemented, indemnify any and all persons whom it shall have power to indemnify under said section, to the full extent provided in the corporation's By-Laws, from and against any and all of the expenses, liabilities or other matters referred to in or covered by said section, and the indemnification provided for herein shall not be deemed exclusive of any other rights to which a person indemnified may be entitled under any agreement, vote of stockholders or disinterested Directors or otherwise, both as to action in his official capacity and as to action in another

capacity while holding such office, and shall continue as to a person who has ceased to be Director, officer, employee or agent and shall inure to the benefit of the heirs, executors and administrators of such a person.

10. AMENDMENT. From time to time any of the provisions of this Certificate of Incorporation may be amended, altered or repealed, and other provisions authorized by the laws of the State of Delaware at the time in force may be added or inserted in the manner and at the time prescribed by said laws, and all rights at any time conferred upon the stockholders of the corporation by this Certificate of Incorporation are granted subject to the provisions of this Article 10.

11. CLASSIFIED BOARD OF DIRECTORS

(a) The number of directors of the corporation shall be the number, not less than 3 nor more than 12, fixed from time to time by the Board of Directors. The Board of Directors may be enlarged only by vote of a majority of the directors then in office.

(b) Commencing at the annual meeting of the stockholders in 1995, the directors shall be divided into three classes, designated Class I, Class II and Class III. Each class shall consist, as nearly as may be possible, of one third of the number of directors constituting the entire Board of Directors. At the annual meeting of the stockholders held in 1995, Class I directors shall be elected for a one year term, Class I directors shall be elected for a two year term, and Class III directors shall be elected for a three year term, and in each case until their successors are duly elected and qualified. Commencing in 1996, at each annual meeting of the stockholders successors to the class of directors whose terms expire at that annual meeting of stockholders shall be elected by stockholders for a three year term and until their successors are duly elected and qualified. If the number of directors constituting the entire Board of Directors shall be changed as provided in paragraph (a) of this Article 11, the increase or decrease shall be apportioned among the classes so as to maintain the number of directors in each class as nearly equal as possible.

(c) Any director elected to fill a vacancy resulting from an increase in any class or from the removal from office, death, disability, resignation or disqualification of a director or other cause shall hold office for the remaining term of the class to which such director is elected. No decrease in the size of the Board of Directors shall have the effect of removing or shortening the term of any incumbent director.

(d) Whenever the holders of any series of Preferred Stock issued pursuant to the provisions of Part 4.3 of Article 4 of this certificate of incorporation shall have the right, voting as a separate class, to elect directors, the election, term of office, filling of vacancies and other terms of such directorships shall be governed by the terms of this certificate of incorporation applicable to such series or by the resolution or resolutions of the Board of Directors providing for such series, as the case may be, and such directorships shall not be divided into classes or otherwise subject to this Article 11 unless expressly so provided therein.

(e) This Article 11 shall not be amended, altered or repealed except by the affirmative vote of eighty percent (80%) of the votes entitled to be cast by stockholders voting in accordance with Section 4.2.2(a) of Article 4 .


14. CONSIDERATION OF RELEVANT FACTORS IN BUSINESS COMBINATIONS. The Board of Directors of the corporation, when evaluating any offer of another party to
(i) purchase or exchange any securities or property for any outstanding equity securities of the corporation, (ii) merge or consolidate the corporation with another corporation, or (iii) purchase or otherwise acquire all or substantially all of the properties and assets of the corporation, shall, in connection with the exercise of its judgment in determining what is in the best interests of the corporation and its stockholders, give due consideration to all relevant factors, including without limitation: (a) not only the price or other consideration being offered in relation to the then current market price of the corporation's outstanding shares of capital stock, but also the Board of Directors' estimate of the future value of the corporation as an independent going concern and the unrealized value of its property and assets; (b) the financial and managerial resources and future prospects of the other party; and
(c) the possible social, legal, environmental and economic effects of the transaction on the business of the corporation and its subsidiaries and on the employees, customers, suppliers and creditors of the corporation and its subsidiaries and the effects on the communities in which the corporation's facilities are located. In evaluating any such offer on the basis of the foregoing factors, the directors shall be deemed to be performing their duly authorized duties and acting in good faith and in the best interests of the corporation within the meaning of Section 145 of the General Corporation Law of Delaware, as it may be amended from time to time.

IN WITNESS WHEREOF, the undersigned has executed this Restated Certificate of Incorporation on this 13th day of August, 1997. This Restated Certificate of Incorporation is to be filed with the Secretary of State of Delaware and Recorded with the Recorder of Deeds of New Castle County, Delaware, pursuant to
Section 103 and 245 of the Delaware General Corporation Law.

/s/ David M. Lederman
---------------------


David M. Lederman, President


EXHIBIT 3.3

PAGE 1

State of Delaware

OFFICE OF THE SECRETARY OF STATE


I, EDWARD J. FREEL, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO HEREBY CERTIFY THE ATTACHED IS A TRUE AND CORRECT COPY OF THE CERTIFICATE OF DESIGNATION OF "ABIOMED, INC.", FILED IN THIS OFFICE ON THE FOURTEENTH DAY OF AUGUST, A.D. 1997, AT 2:19 O'CLOCK P.M.

A CERTIFIED COPY OF THIS CERTIFICATE HAS BEEN FORWARDED TO THE NEW CASTLE

COUNTY RECORDER OF DEEDS FOR RECORDING.

[STAMP]        /s/ Edward J. Freel
              ----------------------------------------
              Edward J. Freel, Secretary of State

              AUTHENTICATION:     8607157

                        DATE:     08-14-97


CERTIFICATE OF DESIGNATIONS

of

SERIES A JUNIOR PARTICIPATING PREFERRED STOCK

of

ABIOMED,INC.

(Pursuant to Section 151 of the
Delaware General Corporation Law)


ABIOMED, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware (hereinafter called the "Corporation"), hereby certifies that the following resolution was adopted by the Board of Directors of the Corporation as required by Section 151 of the General Corporation Law at a meeting duly called and held on August 13, 1997:

RESOLVED, that pursuant to the authority granted to and vested in the Board of Directors of this Corporation (hereinafter called the "Board of Directors" or the "Board") in accordance with the provisions of the Certificate of Incorporation of the Corporation, the Board of Directors hereby designate 25,000 shares of the Corporation's Class B Preferred Stock, par value $0.01 per share, as "Series A Junior Participating Preferred Stock" of the Corporation and hereby states the designation and number of shares, and fixes the relative rights, preferences, and limitations thereof as follows:

Series A Junior Participating Preferred Stock:

Section 1. Designation and Amount. The shares of this series shall be designated as "Series A Junior Participating Preferred Stock" (the "Series A Preferred Stock") and the number of shares constituting the Series A Preferred Stock shall be 25,000. Such number of shares may be increased or decreased by resolution of the Board of Directors; provided, that no decrease shall reduce the number of shares of Series A Preferred Stock to a number less than the number of shares then outstanding plus the number of shares reserved for issuance upon the exercise of outstanding options, rights or warrants or upon the conversion of any outstanding securities issued by the Corporation convertible into Series A Preferred Stock.

Section 2. Dividends and Distributions.

(A) Subject to the rights of the holders of any shares of any series of Preferred Stock (or any other stock) ranking prior and superior to the Series A Preferred Stock with respect to dividends, the holders of shares of Series A Preferred Stock shall be entitled to receive, when, as and if declared by the Board of Directors out of funds legally available for the purpose, quarterly dividends payable in cash on the last day of March, June, September and December in each year (each such date being referred to herein as a "Quarterly Dividend Payment Date"), commencing on the first Quarterly Dividend Payment Date after the first issuance of a share or fraction of a share of Series A Preferred Stock, in an amount (if any) per share (rounded to the nearest cent), subject to the provision for adjustment hereinafter set forth, equal to 1000 times the aggregate per share amount of all cash dividends, and 1000 times the aggregate per share amount (payable in kind) of all non-cash dividends or other distributions, other than a dividend payable in shares of Common Stock, par value $0.01 per share (the "Common Stock"), of the Company or a subdivision of the outstanding shares of Common Stock (by reclassification or otherwise), declared on the Common Stock since the immediately preceding Quarterly Dividend Payment Date or, with respect to the first Quarterly Dividend Payment Date, since the first issuance of any share or fraction of a share of Series A Preferred Stock. In the event the Corporation shall at any time declare or pay any dividend on the Common Stock payable in shares of Common Stock, or effect a subdivision or combination or consolidation of the outstanding shares of Common Stock (by reclassification or otherwise than by payment of a dividend in shares of Common Stock) into a greater or lesser number of shares of Common Stock, then in each such case the amount to which holders of shares of Series A Preferred Stock were entitled immediately prior to such event under the preceding sentence shall be adjusted by multiplying such amount by a fraction, the numerator of which is the number of shares of Common Stock outstanding immediately after such event and the denominator of which is the number of shares of Common Stock that were outstanding immediately prior to such event.

(B) The Corporation shall declare a dividend or distribution on the Series A Preferred Stock as provided in paragraph (A) of this Section immediately after it declares a dividend or distribution on the Common Stock (other than a dividend payable in shares of Common Stock).

(C) Dividends due pursuant to paragraph (A) of this Section shall begin to accrue and be cumulative on outstanding shares of Series A Preferred Stock from the Quarterly Dividend Payment Date next preceding the date of issue of such shares, unless the date of issue of such shares is prior to the record date for the first Quarterly Dividend Payment Date, in which case dividends on such shares shall begin to accrue from the date of issue of such shares, or unless the date of issue is a Quarterly Dividend Payment Date or is a date after the record date for the determination of holders of shares of Series A Preferred Stock entitled to receive a quarterly dividend and before such Quarterly Dividend Payment Date, in either of which events such dividends shall begin to


accrue and be cumulative from such Quarterly Dividend Payment Date. Accrued but unpaid dividends shall not bear interest. Dividends paid on the shares of Series A Preferred Stock in an amount less than the total amount of such dividends at the time accurued and payable on such shares shall be allocated pro rata on a share-by-share basis among all such shares at the time outstanding. The Board of Directors may fix a record date for the determination of holders of shares of Series A Preferred Stock entitled to receive payment of a dividend or distribution declared thereon, which record date shall be not more than 60 days prior to the date fixed for the payment thereof.

Section 3. Voting Rights. The holders of shares of Series A Preferred Stock shall have the following voting rights:

(A) Subject to the provision for adjustment hereinafter set forth, each share of Series A Preferred Stock shall entitle the holder thereof to 1000 votes on all matters submitted to a vote of the stockholders of the Corporation. In the event the Corporation shall at any time declare or pay any dividend on the Common Stock payable in shares of Common Stock, or effect a subdivision or combination or consolidation of the outstanding shares of Common Stock (by reclassification or otherwise than by payment of a dividend in shares of Common Stock) into a greater or lesser number of shares of Common Stock, then in each such case the number of votes per share to which holders of shares of Series A Preferred Stock were entitled immediately prior to such event shall be adjusted by multiplying such number by a fraction, the numerator of which is the number of shares of Common Stock outstanding immediately after such event and the denominator of which is the number of shares of Common Stock that were outstanding immediately prior to such event.

(B) Except as otherwise provided in the Certificate of Incorporation of the Company, including any other Certificate of Designations creating a series of Preferred Stock or any similar stock, or by law, the holders of shares of Series A Preferred Stock and the holders of shares of Common Stock and any other capital stock of the Corporation having general voting rights shall vote together as one class on all matters submitted to a vote of stockholders of the Corporation.

(C) Except as set forth herein, or as otherwise provided by law, holders of Series A Preferred Stock shall have no special voting rights and their consent shall not be required (except to the extent they are entitled to vote with holders of Common Stock as set forth herein) for taking any corporate action .

Section 4. Certain Restrictions.

(A) Whenever quarterly dividends or other dividends or distributions payable on the Series A Preferred Stock as provided in Section 2 are in arrears, thereafter and until all accrued and unpaid dividends and distributions, whether or not declared, on shares of Series A Preferred Stock outstanding shall have been paid in full, the Corporation shall not:


(i) declare or pay dividends, or make any other distributions, on any shares of stock ranking junior (either as to dividends or upon liquidation, dissolution or winding up) to the Series A Preferred Stock;

(ii) declare or pay dividends, or make any other distributions, on any shares of stock ranking on a parity (either as to dividends or upon liquidation, dissolution or winding up) with the Series A Preferred Stock, except dividends paid ratably on the Series A Preferred Stock and all such parity stock on which dividends are payable or in arrears in proportion to the total amounts to which the holders of all such shares are then entitled; or

(iii) redeem or purchase or otherwise acquire for consideration shares of any stock ranking junior (either as to dividends or upon liquidation, dissolution or winding up) to the Series A Preferred Stock, provided that the Corporation may at any time redeem, purchase or otherwise acquire shares of any such junior stock in exchange for shares of any stock of the Corporation ranking junior (as to dividends and-upon dissolution, liquidation or winding up) to the Series A Preferred Stock.

(B) The Corporation shall not permit any subsidiary of the Corporation to purchase or otherwise acquire for consideration any shares of stock of the Corporation unless the Corporation could, under paragraph (A) of this Section 4, purchase or otherwise acquire such shares at such time and in such manner.

Section 5. Reacquired Shares. Any shares of Series A Preferred Stock purchased or otherwise acquired by the Corporation in any manner whatsoever shall be retired and canceled promptly after the acquisition thereof. All such shares shall upon their cancellation become authorized but unissued shares of Preferred Stock and may be reissued as part of a new series of Preferred Stock subject to the conditions and restrictions on issuance set forth herein, in the Certificate of Incorporation of the Company, including any Certificate of Designations creating a series of Preferred Stock or any similar stock or as otherwise required by law.

Section 6. Liquidation, Dissolution or Winding Up. Upon any liquidation, dissolution or winding up of the Corporation the holders of shares of Series A Preferred Stock shall be entitled to receive an aggregate amount per share, subject to the provision for adjustment hereinafter set forth, equal to 1000 times the aggregate amount to be distributed per share to holders of shares of Common Stock plus an amount equal to any accrued and unpaid dividends. In the event the Corporation shall at any time declare or pay any dividend on the Common Stock payable in shares of Common Stock, or effect a subdivision or combination or consolidation of the outstanding shares of Common Stock (by reclassification or otherwise than by payment of a dividend in shares of Common Stock) into a greater or lesser number of shares of Common Stock, then in each such case the aggregate amount to which holders of shares of Series A Preferred Stock were entitled immediately prior to such event under the preceding sentence shall be adjusted by multiplying such amount by a fraction the numerator of which is the number of shares of

Common Stock outstanding immediately after such event and the denominator of which is the number of shares of Common Stock that were outstanding immediately prior to such event.

Section 7. Consolidation, Merger, etc. In case the Corporation shall enter into any consolidation, merger, combination or other transaction in which the shares of Common Stock are exchanged for or changed into other stock or securities, cash and/or any other property, then in any such case each share of Series A Preferred Stock shall at the same time be similarly exchanged or changed into an amount per share, subject to the provision for adjustment hereinafter set forth, equal to 1000 times the aggregate amount of stock, securities, cash and/or any other property (payable in kind), as the case may be, into which or for which each share of Common Stock is changed or exchanged. In the event the Corporation shall at any time declare or pay any dividend on the Common Stock payable in shares of Common Stock, or effect a subdivision or combination or consolidation of the outstanding shares of Common Stock (by reclassification or otherwise than by payment of a dividend in shares of Common Stock) into a greater or lesser number of shares of Common Stock, then in each such case the amount set forth in the preceding sentence with respect to the exchange or change of shares of Series A Preferred Stock shall be adjusted by multiplying such amount by a fraction, the numerator of which is the number of shares of Common Stock outstanding immediately after such event and the denominator of which is the number of shares of Common Stock that were outstanding immediately prior to such event.

Section 8. Redemption. The shares of Series A Preferred Stock shall not be redeemable.

Section 9. Ranking. Unless otherwise provided in the Certificate of Incorporation or a Certificate of Designations relating to a subsequently- designated series of preferred stock of the Corporation, the Series A Preferred Stock shall rank junior to any other series of the Corporation's preferred stock subsequently issued, as to the payment of dividends and the distribution of assets on liquidation, dissolution or winding up and shall rank senior to the Common Stock.

Section 10. Amendment. The Certificate of Incorporation of the Corporation shall not be amended in any manner, including in a merger or consolidation, which would alter, change, or repeal the powers, preferences or special rights of the Series A Preferred Stock so as to affect them adversely without the affirmative vote of the holders of at least two-thirds of the outstanding shares of Series A Preferred Stock, voting together as a single class.

Section 11. Fractional Shares. Series A Preferred Stock may be issued in whole shares or in any fraction of a share that is one one-thousandth of a share or any integral multiple of such fraction, which shall entitle the holder, in proportion to such holder's fractional shares, to exercise voting rights, receive dividends, participate in distributions and to have the benefit of all other rights of holders of Series A Preferred

Stock. In lieu of fractional shares, the Corporation may elect to make a cash payment as provided in the Rights Agreement for fractions of a share other than one one-thousandth of a share or any integral multiple thereof.


IN WITNESS WHEREOF, this Certificate of Designations is executed on behalf of the Corporation by its President this 13th day of August, 1997.

ABIOMED, INC.

By:/s/ David M. Lederman
---------------------


David M. Lederman


EXHIBIT 5.1

September 29, 1997

ABIOMED, Inc.
33 Cherry Hill Drive
Danvers, MA 01923

RE: Registration Statement on Form S-3 of ABIOMED, Inc. filed on September 29, 1997

Ladies and Gentlemen:

We have acted as counsel to ABIOMED, Inc., a Delaware corporation (the "Company"), in connection with the preparation and filing with the Securities and Exchange Commission of a Registration Statement on Form S-3 (the "Registration Statement") pursuant to which the Company is registering under the Securities Act of 1933, as amended (the "Act"), a total of 2,760,000 shares of common stock, $.01 par value (the "Common Stock") and 2,760,000 Rights, as defined below. Pursuant to the Registration Statement and an underwriting agreement (the "Underwriting Agreement") by and among the Company, Robertson, Stephens & Company and UBS Securities, as representatives of the several underwriters (the "Underwriters") and certain of the Company's Stockholders (the "Selling Stockholders"), in substantially the form to be filed as Exhibit 1.01 to the Registration Statement, the Company proposes to sell to the Underwriters up to 2,610,000 shares of Common Stock (the "Company Shares") and the Selling Stockholders propose to sell to the Underwriters 150,000 shares of Common Stock (the "Selling Stockholder Shares"). The Rights are issuable pursuant to that certain Rights Agreement, dated as of August 13, 1997 (the "Rights Agreement"), providing, in effect, for the delivery of a right (a "Right"), along with each share of Common Stock issued by the Company pursuant to the Underwriting Agreement. This opinion is being rendered in connection with the filing of the Registration Statement. Unless otherwise indicated, capitalized terms used herein shall have the meanings ascribed thereto in the Underwriting Agreement.

For purposes of this opinion, we have assumed, without any investigation,
(i) the legal capacity of each natural person, (ii) the full power and authority of each entity and person other than the Company to execute, deliver and perform each document heretofore executed and delivered or hereafter to be executed and delivered and to do each other act heretofore done or hereafter to be done by such entity or person, (iii) the due authorization by each entity or person other than the Company of each document heretofore executed and delivered or hereafter to be executed and delivered and to do each other act heretofore done or to be done by such entity or person, (iv) the due execution and delivery by each entity or person other than the Company of


ABIOMED, Inc.
September 29, 1997

Page 2

each document heretofore executed and delivered or hereafter to be executed and delivered by such entity or person, (v) the legality, validity, binding effect and enforceability as to each entity or person other than the Company of each document heretofore executed and delivered or hereafter to be executed and delivered and of each other act heretofore done or hereafter to be done by such entity or person, (vi) the genuineness of each signature on, and the completeness of each document submitted to us as an original, (vii) the conformity to the original of each document submitted to us as a copy, (viii) the authenticity of the original of each document submitted to us as a copy,
(ix) the completeness, accuracy and proper indexing of all governmental and judicial records searched and (x) no modification of any provision of any document, no waiver of any right or remedy and no exercise of any right or remedy other than in a commercially reasonable and conscionable manner and in good faith.

In connection with this opinion, we have examined the following (collectively, the "Documents"):

(i) the Restated Certificate of Incorporation of the Company filed as Exhibit 3.1 to the Registration Statement;

(ii) the Restated Bylaws of the Company incorporated by reference as Exhibit 3.2 to the Registration Statement;

(iii) the corporate minute books or other records of the Company;

(iv) a specimen certificate for the Common Stock incorporated by reference as Exhibit 4.1 to the Registration Statement;

(v) the Rights Agreement incorporated by reference as Exhibit 4.03 to the Registration Statement; and

(vi) the Form of Underwriting Agreement to be filed by amendment as Exhibit 1.1 to the Registration Statement.

The opinions expressed herein are based solely upon (i) our review of the Documents, (ii) discussions with David M. Lederman, the Chairman of the Board, Chief Executive Officer and President and Assistant Secretary of the Company and John F. Thero, the Company's Vice President-Finance, Treasurer and Assistant Secretary and Chief Financial Officer; (iii) the representations and warranties of the Company and the Selling Stockholders contained in the Underwriting Agreement and the exhibits thereto, (iv) discussions with those of our attorneys who have devoted substantive attention to the matters contained herein, and (v) such review of published sources of law as we have deemed necessary.

Our opinions contained herein are limited to the laws of The Commonwealth of Massachusetts, the general corporate laws of the State of Delaware and the federal law of the United States of America.


ABIOMED, Inc.
September 29, 1997

Page 3

Based upon and subject to the foregoing, we are of the opinion that:

1. The Company Shares to be sold by the Company under the circumstances contemplated in the Registration Statement are duly authorized and, when delivered pursuant to the Underwriting Agreement, will be validly issued, fully paid and nonassessable.

2. The Selling Stockholder Shares to be sold by the Selling Stockholders under the circumstances contemplated in the Registration Statement are duly authorized, validly issued, fully paid and nonassessable.

3. The Rights have been duly authorized and, when issued in accordance with the terms of the Rights Agreement, will be validly issued, fully paid and nonassessable.

We understand that this opinion is to be used in connection with the Registration Statement. We consent to the filing of this opinion as an Exhibit to said Registration Statement and to the reference to our firm wherever it appears in the Registration Statement, including the prospectuses constituting a part thereof and any amendments thereto. This opinion may be used in connection with the offering of the Shares only while the Registration Statement, as it may be amended from time to time, remains in effect.

Very truly yours,

BROWN, RUDNICK, FREED & GESMER
By: BROWN, RUDNICK, FREED & GESMER, P.C.

By:  /s/ Philip J. Flink
     ------------------------------------------
     Philip J. Flink, A Member
     Duly Authorized


EXHIBIT 23.1

CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS

As independent public accountants, we hereby consent to the use of our report dated May 8, 1997 and to all references to our Firm include in or made a part of this Registration Statement.

                                          /s/ ARTHUR ANDERSEN LLP

Boston, MA


September 22, 1997


EXHIBIT 99.2

EXECUTION COPY

COMMON STOCK PURCHASE AGREEMENT

between

ABIOMED, Inc.

and

GENZYME CORPORATION

dated as of July 14, 1997


TABLE OF CONTENTS

ARTICLE 1. PURCHASE AND SALE OF SHARES...................................................................... 1

1.1. Authorization.......................................................................................... 1
1.2. Sale and Purchase of the Shares........................................................................ 1
1.3. Delivery of Certificates............................................................................... 1

ARTICLE 2.  REPRESENTATIONS AND WARRANTIES OF ABIOMED....................................................... 1

2.1. Organization and Qualification......................................................................... 1
2.2. Capitalization......................................................................................... 2
2.3. Issuance and Sale of Shares............................................................................ 3
2.4. Authority for Agreement................................................................................ 3
2.5. SEC Reports............................................................................................ 3
2.6. Financial Statements................................................................................... 3
2.7. Subsidiaries........................................................................................... 4
2.8. Absence of Undisclosed ABIOMED Liabilities............................................................. 4
2.9. No Material Adverse Change............................................................................. 4
2.10. Tax Matters........................................................................................... 5
2.11. No Breach............................................................................................. 5
2.12. Actions and Proceedings............................................................................... 6
2.13. Compliance with Laws.................................................................................. 6
2.14. Brokerage............................................................................................. 6
2.15. Full Disclosure....................................................................................... 6

ARTICLE 3.  REPRESENTATIONS AND WARRANTIES OF GENZYME....................................................... 6

3.1. Authority for Agreement................................................................................ 7
3.2. Investment............................................................................................. 7
3.3. Restrictions on Transferability; Legend................................................................ 7
3.4. Information............................................................................................ 7
3.5. Brokerage.............................................................................................. 8

ARTICLE 4.  CONDITIONS PRECEDENT............................................................................ 8

ARTICLE 4.  COVENANTS OF ABIOMED............................................................................ 8

5.1. Corporate Existence.................................................................................... 8
5.2. Reporting Status....................................................................................... 9
5.3. Listing................................................................................................ 9
5.4. Use of Proceeds........................................................................................ 9
5.5. Information to be Furnished............................................................................ 9

ARTICLE 6.  COVENANTS OF GENZYME............................................................................ 9

6.1. Standstill Agreement................................................................................... 9
6.2. Voting of Shares.......................................................................................11
6.3. Henri A. Termeer.......................................................................................11
6.4. Release of Restrictions................................................................................11


ARTICLE 7.  REGISTRATION RIGHTS.............................................................................11

7.1. Certain Definitions....................................................................................11
7.2. Required Registration..................................................................................12
7.3. Incidental Registration................................................................................13
7.4. Conditions of Obligations to Register Shares...........................................................14
7.5. Registration Procedures................................................................................14
7.6. Description of Expenses................................................................................17
7.7. Indemnification........................................................................................17

ARTICLE 8.  CONFIDENTIALITY.................................................................................19

8.1. Non-Disclosure Obligations.............................................................................19
8.2. Exceptions to Non-Disclosure Obligations...............................................................20
8.3. Ownership of Confidential Information..................................................................20
8.4. Destruction of Confidential Information................................................................20
8.5. Material Inside Information............................................................................21
8.6. Terms of this Agreement................................................................................21

ARTICLE 9.  JOINT DEVELOPMENT AND COLLABORATIONS............................................................21

10.1. Assignment............................................................................................21
10.2. Severability..........................................................................................21
10.3. Notices...............................................................................................22
10.4. Applicable Law........................................................................................22
10.5. Entire Agreement......................................................................................22
10.6. Headings..............................................................................................23
10.7. Counterparts..........................................................................................23


COMMON STOCK PURCHASE AGREEMENT

THIS COMMON STOCK PURCHASE AGREEMENT dated as of July 14, 1997 (the "Agreement") is between ABIOMED, Inc., a Delaware corporation having its principal place of business at 33 Cherry Hill Drive, Danvers, Massachusetts 01923 ("ABIOMED"), and Genzyme Corporation, a Massachusetts corporation having its principal place of business at One Kendall Square, Cambridge, Massachusetts 02139 ("Genzyme"). ABIOMED and Genzyme are sometimes referred to herein individually as a "Party" and collectively as the "Parties."

In consideration of the mutual promises and of the covenants contained herein, the Parties hereby agree as follows:

ARTICLE 1. PURCHASE AND SALE OF SHARES

1.1. Authorization.

ABIOMED has duly authorized the issuance and sale to Genzyme of 1,153,846 shares (the "Shares") of its Common Stock, $0.01 par value per share ("Common Stock").

1.2. Sale and Purchase of the Shares.

Concurrently with the execution and delivery of this Agreement, ABIOMED hereby issues and sells to Genzyme, and Genzyme hereby purchases from ABIOMED, the Shares at a purchase price of $13.00 per Share, for an aggregate purchase price of Fourteen Million Nine Hundred Ninety-Nine Thousand Nine Hundred Ninety- Eight Dollars ($14,999,998), payable by Genzyme to ABIOMED upon execution of this Agreement.

1.3. Delivery of Certificates.

On the date hereof, ABIOMED will deliver to Genzyme one or more certificates representing the Shares registered in the name of Genzyme against payment by Genzyme of the purchase price by check or wire transfer.

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED

Except as otherwise set forth in the disclosure schedule delivered to Genzyme on the date hereof (the "Disclosure Schedule"), the section numbers of which are numbered to correspond to the sections of this Agreement to which they refer, ABIOMED represents and warrants to Genzyme as follows:

2.1. Organization and Qualification.

1

Each of ABIOMED and the Subsidiaries (as defined in Section 2.7) is a corporation or partnership duly organized, validly existing and in good standing under the laws of its state or jurisdiction of incorporation or formation with full power and authority to own, lease and operate its assets, properties and business and to carry on its business as now being and as heretofore conducted. Each of ABIOMED and the Subsidiaries is qualified or otherwise authorized to transact business as a foreign corporation or partnership in all jurisdictions in which such qualification or authorization is required by law, except for jurisdictions in which the failure to so qualify or be authorized would not have a material adverse effect on the assets, properties, business, operations or condition (financial or otherwise) of ABIOMED and the Subsidiaries taken as a whole (the "Business of ABIOMED").

2.2. Capitalization.

(a) ABIOMED is authorized to issue 25,000,000 shares of Common Stock, of which 7,017,872 shares were issued and outstanding as of June 30, 1997, 2,346,000 shares of Class A Common Stock, $0.01 par value per share, none of which are issued and outstanding, 150,000 shares of Class A Preferred Stock, $0.01 par value per share, none of which are issued and outstanding, and 1,000,000 shares of Class B Preferred Stock, $0.01 par value per share, none of which are issued and outstanding. No other class of capital stock of ABIOMED is authorized or outstanding. All of the issued and outstanding shares of ABIOMED's capital stock are duly authorized and are validly issued, fully paid, nonassessable and free of preemptive rights. None of the issued and outstanding shares have been issued in violation of any federal or state law except for violations that would not have a material adverse effect on the Business of ABIOMED.

(b) Options representing in the aggregate the right to purchase 919,785 shares of Common Stock pursuant to ABIOMED's 1992 Combination Stock Option Plan and ABIOMED's 1989 Non-Qualified Stock Option Plan for Non-Employee Directors are outstanding as of the date hereof.

(c) 90,718 shares of Common Stock are reserved for issuance under ABIOMED's 1988 Employee Stock Purchase Plan as of the date hereof.

(d) Except as set forth in paragraphs (a), (b) and (c) of this
Section 2.2, Section 2.2 of the Disclosure Schedule or as a result of the exercise of outstanding options or rights set forth therein, there are not, as of the date hereof, any other shares of ABIOMED capital stock authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements or commitments obligating ABIOMED to issue, transfer, sell, repurchase or redeem any shares of its capital stock or other securities of ABIOMED. To the best knowledge of ABIOMED, there are no written stockholder agreements, voting trusts, proxies or other agreements, instruments or

2

understandings with respect to the voting of the capital stock of
ABIOMED.

2.3. Issuance and Sale of Shares.

The issuance and sale of the Shares by ABIOMED has been duly authorized and the Shares have been duly reserved for issuance by all necessary corporate action on the part of ABIOMED, and the Shares, when issued and delivered against payment therefor, will be duly and validly issued, fully paid and non- assessable. Based in part on the representations made by Genzyme set forth in Article 3 below, the offer, issuance and sale of the Shares pursuant to this Agreement are exempt from registration under the Securities Act of 1933, as amended (the "Securities Act"), and applicable state securities laws. ABIOMED has complied with all applicable federal and state securities laws and with the Nasdaq By-Laws in connection with the offer, issuance and sale of the Shares.

2.4. Authority for Agreement.

The execution, delivery and performance by ABIOMED of this Agreement has been duly authorized by all necessary corporate action, and this Agreement has been duly executed and delivered by ABIOMED. This Agreement constitutes the valid and binding obligation of ABIOMED enforceable against ABIOMED in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

2.5. SEC Reports.

ABIOMED has previously delivered to Genzyme its (a) Annual Report on Form 10-K for the year ended March 31, 1997 (the "ABIOMED 10-K"), as filed with the Securities and Exchange Commission (the "SEC"), (b) all proxy statements

relating to ABIOMED's meetings of stockholders held or currently scheduled to be held since March 31, 1997 and (c) all other reports filed by ABIOMED with the SEC under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), since March 31, 1997. As of their respective dates, such reports complied in all material respects with applicable SEC requirements and did not contain any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading. ABIOMED has timely filed with the SEC all reports required to be filed under Section 13, 14 or 15(d) of the Exchange Act since March 31, 1997.

2.6. Financial Statements.

The financial statements contained in the ABIOMED 10- K have been prepared from, and are in accordance with, the books and records of ABIOMED and present fairly, in all material respects, the financial condition and results of operations of ABIOMED as of and for the periods presented therein, all in conformity with United States generally accepted accounting principles, consistently applied, except as otherwise noted therein.

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2.7. Subsidiaries.

(a) The Disclosure Schedule sets forth all of the Subsidiaries and the jurisdiction in which each is incorporated or organized. Except as set forth on the Disclosure Schedule, all issued and outstanding shares or partnership interests of each Subsidiary are owned directly by ABIOMED free and clear of any charges, liens, encumbrances, security interests or adverse claims. As used in this Agreement, "Subsidiary" means any corporation, partnership or other legal entity of which ABIOMED or any Subsidiary owns, directly or indirectly, 50% or more of the stock or other equity interest entitled to vote for the election of directors.

(b) Except as set forth on the Disclosure Schedule, there are not as of the date hereof any other shares of capital stock or other equity interest of any Subsidiary authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements, claims or commitments of any nature whatsoever obligating any Subsidiary to issue, transfer, deliver, sell, repurchase or redeem any shares of the capital stock or other equity interest of any Subsidiary or obligating ABIOMED or any Subsidiary to grant, extend or enter into any such agreement. To the best knowledge of ABIOMED, there are no stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the capital stock of any Subsidiary.

(c) Except for the Subsidiaries, ABIOMED does not directly or indirectly own or have any investment in any of the capital stock of, and is not a party to a partnership or joint venture with, any other person.

2.8. Absence of Undisclosed ABIOMED Liabilities.

As of March 31, 1997, ABIOMED and the Subsidiaries had no material liabilities of any nature, whether accrued, absolute, contingent or otherwise,
(a) required to be reflected or disclosed on the balance sheets dated March 31, 1997 (or the notes thereto) included in the ABIOMED 10-K that were not adequately reflected or reserved against on such balance sheets or (b) for the payment of any dividends, or any other distribution, to the stockholders of ABIOMED. ABIOMED and the Subsidiaries have no such liabilities, other than liabilities (i) adequately reflected or reserved against on such balance sheet,
(ii) incurred since March 31, 1997 in the ordinary course of business and consistent with past practice or (iii) that would not, in the aggregate, have a material adverse effect on the Business of ABIOMED.

2.9. No Material Adverse Change.

Since March 31, 1997, there has not been any material adverse change in the Business of ABIOMED.

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2.10. Tax Matters.

(a) ABIOMED and each of the Subsidiaries have filed all tax reports and returns required to be filed by them and have paid or will timely pay all taxes and other charges shown as due on such reports and returns. Neither ABIOMED nor any of the Subsidiaries is delinquent in the payment of any material tax assessment or other governmental charge (including without limitation applicable withholding taxes). Any provision for taxes reflected in the financial statements referenced in Section 2.6 above is, to the best knowledge of ABIOMED, adequate for payment of any and all tax liabilities for periods ending on or before March 31, 1997 and there are no tax liens on any assets of ABIOMED or the Subsidiaries except liens for current taxes not yet due.

(b) Except as set forth in the Disclosure Schedule, there has not been any audit of any tax return filed by ABIOMED or any of the Subsidiaries and no audit of any such tax return is in progress and neither ABIOMED nor any Subsidiary has been notified by any tax authority that any such audit is contemplated or pending. ABIOMED knows of no material tax deficiency or claim for additional taxes asserted or threatened to be asserted against ABIOMED or any of the Subsidiaries by any taxing authority and ABIOMED knows of no grounds for any such assessment. No extension of time with respect to any date on which a tax return was or is to be filed by ABIOMED or any of the Subsidiaries is in force, and no waiver or agreement by ABIOMED or any of the Subsidiaries is in force for the extension of time for the assessment or payment of any tax. For purposes of this Agreement, the term "tax" includes all federal, state, local and foreign taxes or assessments, including income, sales, gross receipts, excise, use, value added, royalty, franchise, payroll, withholding, property and import taxes and any interest or penalties applicable thereto.

2.11. No Breach.

The execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby will not: (a) violate any provision of the certificate of incorporation or by-laws of ABIOMED; (b) violate, conflict with or result in the breach of any of the terms or conditions of, result in modification of the effect of, or otherwise give any other contracting party the right to terminate, or constitute (or with notice or lapse of time or both constitute) a default under, any material instrument, contract or other agreement to which ABIOMED or any of the Subsidiaries is a party or to which any of the assets or properties of ABIOMED or any of the Subsidiaries may be bound or subject; (c) violate any order, judgment, injunction, award or decree of any court, arbitrator or governmental or regulatory body against, or binding upon, ABIOMED, any Subsidiary or upon any of their respective securities, properties, assets or businesses; (d) violate any statute, law or regulation of any jurisdiction as such statute, law or regulation relates to ABIOMED, any Subsidiary or any of their respective

5

securities, properties, assets or businesses; (e) require the approval, consent or authorization of, or registration or filing with, any foreign, federal, state, local or other governmental or regulatory body or the approval, consent, waiver or notification of any stockholder, creditor, lessor or other person; or
(f) result in the creation of any lien or other encumbrance on the assets or properties of ABIOMED or any of the Subsidiaries, excluding from clauses (b) -
(f) such matters as would not in the aggregate have a material adverse effect on the Business of ABIOMED or upon the transactions contemplated hereby.

2.12. Actions and Proceedings.

There are no outstanding orders, judgments, injunctions, awards or decrees of any court, governmental or regulatory body or arbitration tribunal against ABIOMED, any Subsidiary or any of their respective properties or assets. There are no actions, suits or claims or legal, administrative or arbitral proceedings or, to the best knowledge of ABIOMED, investigations (whether or not the defense thereof or liabilities in respect thereof are covered by insurance) pending or, to the best knowledge of ABIOMED, threatened against ABIOMED, any Subsidiary or any of their respective properties or assets.

2.13. Compliance with Laws.

To its knowledge, neither ABIOMED nor any of the Subsidiaries is in violation of any statute, law, rule or regulation, or in default with respect to any judgment, writ, injunction, decree, rule or regulation of any court, governmental or regulatory body or arbitration tribunal, including without limitation laws relating to environmental protection, health and safety matters and labor and employment practices, except for such violations or defaults which do not, individually or in the aggregate, materially and adversely affect the Business of ABIOMED.

2.14. Brokerage.

Except as set forth in the Disclosure Schedule, no broker, finder, agent or similar intermediary has acted on behalf of ABIOMED in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with ABIOMED or any action taken by ABIOMED.

2.15. Full Disclosure.

The representations and warranties of ABIOMED contained in this Agreement, together with the ABIOMED 10-K, taken as a whole as of the date hereof, do not
(a) contain an untrue statement of a material fact or omit to state a material fact required to be stated or necessary to make the statements made, in light of the circumstances under which made, not false or misleading or (b) omit to state a material fact known to ABIOMED that reasonably could be expected to materially adversely affect the Business of ABIOMED.

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF GENZYME

6

Genzyme hereby represents and warrants to ABIOMED as follows:

3.1. Authority for Agreement.

The execution, delivery and performance by Genzyme of this Agreement has been duly authorized by all necessary corporate action, and this Agreement has been duly executed and delivered by Genzyme. This Agreement constitutes the valid and binding obligation of Genzyme enforceable against Genzyme in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

3.2. Investment.

Genzyme is an accredited investor, as defined in Rule 501 of Regulation D under the Securities Act. Genzyme is acquiring the Shares solely for its own account for investment purposes as a principal and not with a view to the public resale or distribution of all or any part thereof; provided, however, that in making such representation, Genzyme does not agree to hold the Shares for any minimum or specific term and reserves the right to sell, transfer or otherwise dispose of the Shares at any time in accordance with the terms of this Agreement and with federal and state securities laws applicable to such sale, transfer or disposition.

3.3. Restrictions on Transferability; Legend.

Genzyme understands that the Shares have not been registered under the Securities Act or under the securities laws of any state or other jurisdiction in reliance upon exemptions thereunder. Genzyme acknowledges and is aware that the Shares cannot be resold unless the Shares are registered under the Securities Act and any applicable securities law of any state or other jurisdiction, or an exemption from registration is available. Each certificate representing the Shares shall bear a legend in substantially the following form (unless such Shares have been transferred pursuant to a registration statement under the Securities Act or, in the opinion of counsel acceptable to ABIOMED, such a legend is not required):

THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR ANY STATE SECURITIES LAW AND MAY NOT BE TRANSFERRED EXCEPT (i) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT OR (ii) UPON FIRST FURNISHING TO THE COMPANY AN OPINION OF COUNSEL SATISFACTORY TO IT THAT SUCH TRANSFER IS NOT IN VIOLATION OF THE REGISTRATION REQUIREMENTS OF THE ACT OR ANY STATE SECURITIES LAW.

3.4. Information.

Genzyme has reviewed (a) the representations of ABIOMED contained in this Agreement and (b) the ABIOMED 10-K and has had the opportunity to make inquiry concerning

7

ABIOMED and its business and personnel. The officers of ABIOMED have made available to Genzyme any and all written information that it has requested and have answered to Genzyme's satisfaction all inquiries made by Genzyme. Genzyme acknowledges that Henri A. Termeer, President and Chief Executive Officer of Genzyme, is a member of the Board of Directors of ABIOMED, and in that capacity Mr. Termeer has knowledge of the Business of ABIOMED.

3.5. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of Genzyme in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with Genzyme, or any action taken by it.

ARTICLE 4. CONDITIONS PRECEDENT

Contemporaneously with the execution of this Agreement, ABIOMED shall deliver to Genzyme:

(a) The certificate of incorporation, as amended, of ABIOMED, certified by the Secretary of State of Delaware as of the most recent practicable date;

(b) Certificates, as of the most recent practicable date, as to the corporate good standing and legal existence of ABIOMED issued by the Secretary of State of Delaware and the Secretary of the Commonwealth of Massachusetts, each confirming such good standing and legal existence as of such date;

(c) By-laws of ABIOMED, certified by its Secretary as of the date hereof;

(d) Resolutions of the Board of Directors of ABIOMED authorizing and approving this Agreement and the issuance of the Shares hereby, certified by the Secretary of ABIOMED as of the date hereof; and

(e) An opinion of counsel to ABIOMED, dated as of the date hereof and addressed to Genzyme, in a form reasonably acceptable to Genzyme and its counsel.

ARTICLE 5. COVENANTS OF ABIOMED

5.1. Corporate Existence.

ABIOMED will do or cause to be done all things necessary to preserve and keep in full force and effect its corporate existence; provided, however, nothing herein shall prevent or limit the right of ABIOMED to merge or consolidate with any other entity or to sell all or substantially

8

all of its assets to another entity followed by a dissolution of ABIOMED, or to enter into any similar transaction.

5.2. Reporting Status.

For so long as Genzyme or any affiliate of Genzyme beneficially owns any of the Shares, ABIOMED (a) shall timely file with the SEC any and all reports required to be so filed pursuant to the Exchange Act and (b) shall not terminate its status as an issuer required by the Exchange Act to file reports thereunder even if the Exchange Act or the rules or regulations thereunder would permit such termination.

5.3. Listing.

For so long as Genzyme or any affiliate of Genzyme beneficially owns any of the Shares, ABIOMED shall cause the Common Stock to continue to be listed for trading on Nasdaq or on a national securities exchange.

5.4. Use of Proceeds.

ABIOMED will use amounts paid for the Shares hereunder for working capital and general corporate purposes, including research and development of new products and product enhancements, including the development of a battery- powered implantable total artificial heart, subject to adjustment based upon the results of development efforts, delays or changes in governmentally required testing and approval procedures, changing market conditions and other risks described in the ABIOMED 10-K.

5.5. Information to be Furnished.

For so long as Genzyme or any affiliate of Genzyme holds Shares representing at least 1% of the outstanding shares of Common Stock, ABIOMED will furnish promptly to Genzyme copies of (a) each report and proxy statement filed by ABIOMED with the SEC pursuant to Section 13(a), 14 or 15(d) of the Exchange Act, (b) all financial statements, periodic and special reports and investor relations materials as ABIOMED may distribute to all holders of Common Stock generally and (c) all press releases issued by ABIOMED.

ARTICLE 6. COVENANTS OF GENZYME

6.1. Standstill Agreement.

Genzyme agrees that, unless it has obtained the prior written consent of ABIOMED or the restrictions contained in this Article 6 have otherwise been released or suspended as provided below, it will not, nor will it allow its Affiliates (as that term is defined in Rule 12b-2 under the Exchange Act, regardless of whether such person is an Affiliate on the date hereof) to:

(a) acquire, offer to acquire or enter into any agreement to acquire, directly or indirectly, by purchase or otherwise, record or beneficial ownership of any

9

additional voting securities of ABIOMED or direct or indirect rights or options to acquire (through purchase, exchange, conversion or otherwise) voting securities of ABIOMED;

(b) "solicit" proxies with respect to voting securities under any circumstances, in any way participate in any "solicitation" of "proxies" or become a "participant" in any "election contest" relating to the election of directors of ABIOMED, as such terms are defined in Regulation 14A under the Exchange Act;

(c) deposit any voting securities in a voting trust or subject them to a voting agreement or other agreement of similar effect;

(d) call any special meeting of stockholders of ABIOMED or initiate or participate in the initiation of any special meeting of stockholders of ABIOMED for any purpose;

(e) initiate, propose or otherwise solicit stockholders for the approval of one or more stockholder proposals at any time, or induce or attempt to induce any other person to initiate any stockholder proposal;

(f) request, or take any action to obtain or retain from ABIOMED, directly or indirectly, any list of holders of securities (other than to avail itself of the inspection rights set forth in Sections 219 and 220 of the Delaware General Corporation Law, or any similar successor statutory provisions, for any proper purpose);

(g) fail to withdraw any proposal relating to any matter set forth in this Section 6.1 that, in the written opinion of counsel to ABIOMED, would require ABIOMED to make a public announcement with respect thereto;

(h) form, join or in any way participate in a "group" (within the meaning of Section 13(d)(3) of the Exchange Act) with respect to any voting securities of ABIOMED;

(i) assist, advise, encourage or influence in any respect any third party to seek to control management of ABIOMED including, without limitation (i) proposing any business combination or similar transaction with, a change in control of, or any restructuring, recapitalization or other extraordinary transaction involving, ABIOMED, (ii) influencing the management, board of directors or policies of ABIOMED or (iii) acquiring, holding, voting or disposing of voting securities of ABIOMED; or

(j) take any action individually or jointly with any partnership, limited partnership, syndicate, or other group or assist any other person,

10

corporation, entity or group in taking any action it could not take individually under the terms of this Agreement.

6.2. Voting of Shares.

For so long as the restrictions contained in Section 6.1 remain in effect, Genzyme shall take such action as may be required so that (a) all voting securities held by it or any of its Affiliates shall be present for purposes of determining a quorum at every meeting of the holders of Common Stock and (b) such securities shall be voted in the same proportion as the votes cast by holders of the same class of voting securities other than Genzyme and its Affiliates, or, in Genzyme's discretion, in accordance with the recommendations of ABIOMED's Board of Directors.

6.3. Henri A. Termeer.

The restrictions of this Article 6 shall not prohibit (i) the grant to Henri A. Termeer, in connection with his position as a member of the Board of Directors of ABIOMED, of shares of Common Stock or options to acquire shares of Common Stock, or the exercise by Mr. Termeer of any such options or (ii) the exercise by Mr. Termeer of his fiduciary duties as a member of the Board of Directors of ABIOMED.

6.4. Release of Restrictions.

Notwithstanding the foregoing, the restrictions contained in this Article 6:

(a) shall be suspended during such time as the Board of Directors of ABIOMED determines to accept bids from any responsible bidder to obtain the best price for the sale of ABIOMED, but only so long as ABIOMED continues to accept such bids or negotiate or consummate a transaction with any bidder;

(b) shall be suspended during such time as any third party makes an unsolicited offer to acquire more than fifty percent (50%) of the outstanding voting securities of ABIOMED, but only so long as such offer is outstanding; and

(c) shall be released after the fifth anniversary of the date hereof.

ARTICLE 7. REGISTRATION RIGHTS

7.1. Certain Definitions. As used in this Article 7, the following terms shall have the following respective meanings:

11

(a) "Holders" shall mean Genzyme and any of its successors and assigns (other than successors and assigns who acquire the Shares pursuant to a registered public offering or pursuant to a transaction covered by Rule 144 under the Securities Act) who hold at least 5% of the Common Stock.

(b) "Registration Expenses" and "Selling Expenses" shall mean the expenses so described in Section 7.6. "Other Holders" shall mean all holders of the Company's securities other than Holders.

(d) "Underwriter" shall mean each person who is or may be deemed an "underwriter," as that term is defined in Section 2(11) of the Securities Act, in respect of securities which shall have been registered by ABIOMED under the Securities Act pursuant to any of the provisions of this Article 7.

7.2. Required Registration.

(a) At any time after the first anniversary of the date hereof and prior to the seventh anniversary of the date hereof, the Holder(s) of at least 25% of the then unregistered Shares may notify ABIOMED in writing that such Holder(s) intend to offer or cause to be offered for sale unregistered Shares and request ABIOMED to cause such Shares to be registered under the Securities Act if such registration may be effected on Form S-3 (or any similar or successor form promulgated by the SEC). Such right to require registration shall be available to Holders on not more than a total of three (3) occasions, and on not more than one (1) occasion during any twelve (12) month period, provided such right shall be deemed to have been used only upon a registration statement on Form S-3, or successor form, becoming and remaining effective in accordance with such request and the provisions hereof.

(b) Upon a request pursuant to Section 7.2(a), ABIOMED will use commercially reasonable efforts as soon as practicable thereafter to prepare and file a registration statement on the appropriate form covering such Shares. Neither ABIOMED nor any Other Holder may include any securities in any registration statement requested pursuant to this Section 7.2 which relates to an underwritten offering unless the underwriter or underwriters managing the offering shall determine and advise in writing that such inclusion will not interfere with the marketing of the securities to be offered by the requesting Holder or Holders. Any Holder or Holders intending to request a registration pursuant to
Section 7.2(a) shall notify each other Holder of such request at least thirty (30) days prior to making the request and shall permit each such other Holder to join such request provided that such other Holder, within fifteen (15) days of receipt of such

12

notification, so indicates his or her intention in writing to the Holder or Holders from which such notification was received. ABIOMED, if requested, shall provide reasonable assistance in such notification process. If the underwriter managing such an offering shall determine that the number of Shares proposed to be included would interfere with the marketing of the same, then the number of Shares proposed to be included in such registration statement shall be reduced to the extent deemed appropriate by such managing underwriter pro rata among the Holders joining in such request in proportion to the number of Shares then held by each, giving effect to the provisions of the last two sentences of Section 7.3 below. ABIOMED shall have the right once per request to defer for a reasonable period (not to exceed six (6) months) the filing of any registration statement requested hereunder if, in the reasonable judgment of ABIOMED's Board of Directors, such registration would materially interfere with or materially and adversely affect the aftermarket of any recently completed public offering, or any then existing negotiations for financing arrangements of ABIOMED, or any material business transaction then pending or being negotiated, or any arrangement or plan of ABIOMED, then pending or being negotiated in good faith, relating to any acquisition, disposition, merger or similar transaction.

7.3. Incidental Registration.

If ABIOMED for itself or any of its security holders shall at any time or times after the first anniversary of the date hereof and prior to the seventh anniversary of the date hereof determine to register under the Securities Act any shares of Common Stock in an underwritten public offering (other than (a) the registration of an offer and sale of securities to employees of, or other persons providing services to ABIOMED pursuant to an employee or similar benefit plan, registered on Form S-8 or comparable form; or (b) relating to a merger, acquisition or other transaction of the type described in Rule 145 under the Securities Act or comparable rule, registered on Form S-4 or similar form), ABIOMED will notify each Holder in each case of such determination at least twenty (20) days prior to the filing of such registration statement, and upon the request of a Holder given in writing within ten (10) days after the date of such notice, ABIOMED will use commercially reasonable efforts as soon as practicable thereafter to cause any of the Shares specified by such Holder to be included in such registration statement. Notwithstanding the foregoing, if the managing underwriter determines and advises in writing that the inclusion of all Shares of such requesting Holders and all shares of ABIOMED's Common Stock to be offered by ABIOMED and by Other Holders, whether covered by requests for registration or otherwise included, would interfere with the marketing of the securities to be sold by ABIOMED, or if the registration is at the request of a person or persons with a right to require registration, by that person or persons, then the number of shares of Common Stock otherwise to be included in the registration statement by Holders and Other Holders shall be reduced as follows: (i) there shall first be excluded shares proposed to be included by Other Holders not possessing legal rights to include the same pursuant to this section or any similar provision; and (ii) any further reduction shall be pro rata among such Holders and Other Holders

13

(having such legal rights) in proportion to the number of shares as to which registration is requested by each; provided, however, that there shall be no reduction in the number of shares to be included therein (x) by ABIOMED or (y) if the registration is at the request of a person or persons with a right to require such registration, by that person or persons. For purposes of making any such reduction, each holder (whether a Holder or Other Holder) which is a partnership, together with the affiliates, partners and retired partners of such holder, the estates and family members of any such partners and retired partners and of their spouses, and any trusts for the benefit of any of the foregoing persons shall be deemed to be a single holder and any pro rata reduction with respect to such holder shall be based upon the aggregate amount of Shares sought to be sold by all entities and individuals so included in such holder, and the aggregate reduction so allocated to such holder shall be allocated among the entities and individuals included in such holder in such manner as such partnership may reasonably determine. If the managing underwriter determines and advises in writing that the inclusion in the registration statement of any shares of Common Stock to be sold by stockholders of ABIOMED would interfere with the marketing of the securities to be sold by ABIOMED, no notice need be given to any Holder pursuant to the first sentence of this section and no Holder will have the right to include its Shares in such registration statement.

7.4. Conditions of Obligations to Register Shares.

As conditions to ABIOMED's obligation hereunder to cause a registration statement to be filed or Shares to be included in a registration statement, the Holder shall provide such information and execute such documents as may reasonably be required in connection with such registration.

7.5. Registration Procedures.

If and whenever ABIOMED is required by the provisions of this Article 7 to use commercially reasonable efforts to include any of the Shares in a registration statement filed under the Securities Act, ABIOMED shall as expeditiously as possible:

(a) Prepare and file with the SEC a registration statement with respect to such Shares and use commercially reasonable efforts to cause such registration statement to become effective.

(b) Prepare and file with the SEC such amendments and supplements to such registration statement and the prospectus used in connection therewith as may be necessary to keep such registration statement effective until the Shares covered thereunder have been sold.

(c) Secure the designation and quotation of the Shares on Nasdaq or any national securities exchange on which the Common Stock is then listed.

(d) Furnish to each Holder such number of copies of the prospectus contained in such registration statement (including each preliminary prospectus), in conformity with the requirements of the Securities Act, and such other

14

documents as such Holder may reasonably request in order to facilitate the disposition of the Shares owned by such Holder.

(e) Use commercially reasonable efforts to register or qualify the Shares covered by such registration statement under the securities or "blue sky" laws of such jurisdictions as each selling Holder shall reasonably request, and do any and all other acts and things which may be reasonably necessary or advisable to enable such Holder to consummate the disposition of the Shares owned by such Holder in such jurisdictions during the period specified in Section 7.5(b), provided that ABIOMED shall not be required in connection herewith to execute a general consent to service of process in any jurisdiction.

(f) Notify each Holder immediately of any Shares covered by such registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus contained in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state any material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing, and as promptly as practicable, prepare, file and furnish to the Holder a reasonable number of copies of a supplement or an amendment to such prospectus as may be necessary so that such prospectus does not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing; provided, however, that ABIOMED may delay preparing, filing and distributing any such supplement or amendment if ABIOMED determines in good faith that such supplement or amendment might, in the reasonable judgment of ABIOMED (i) interfere with or affect the negotiation or completion of a transaction that is being contemplated by ABIOMED (whether or not a final decision has been made to undertake such transaction) or
(ii) involve initial or continuing disclosure obligations that are not in the best interests of ABIOMED's stockholders at such time; provided, further, that (x) ABIOMED will give notice (a "Standstill Notice") of any such delay no less than five (5) business days prior to such delay, (y) such delay shall not extend for a period of more than fifteen (15) business days without the written consent of the Holder and (z) ABIOMED may utilize such delay no more than once in each calendar year. Each Holder agrees, upon receipt of a Standstill Notice, forthwith to cease making offers and sales of the Shares pursuant to the registration statement or deliveries of the prospectus contained therein and to return to ABIOMED, for modification and exchange, the copies of such prospectus not theretofore delivered by such Holder; provided that ABIOMED shall forthwith prepare and deliver to such Holder after such delay a reasonable

15

number of copies of any supplement to or amendment of such prospectus that may be necessary so that such prospectus does not include an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing.

(g) Use commercially reasonable efforts to prevent the issuance of any stop order or other order suspending the effectiveness of such registration statement and, if such an order is issued, to obtain the withdrawal at the earliest possible time and to notify the Holder of the issuance of such order and the resolution thereof.

(h) Furnish to the Holder and any Underwriter of the Holder's Shares, on the date that such registration statement becomes effective,
(i) an opinion, dated such date, of outside counsel representing ABIOMED (and reasonably acceptable to the Holder) addressed to the Holder as to the effectiveness of the registration statement and its compliance as to form with the requirements of the Securities Act and such other matters as may be reasonably requested by the Holder (including, if such registration statement relates to an underwritten public offering, such additional matters as are customarily included in opinions delivered by company counsel in underwritten public offerings) and (ii) in the case of an underwriting, a letter, dated such date, from ABIOMED's independent certified public accountants, in form and substance as is customarily given by independent certified public accounts to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holder.

(i) Subject to the Holder entering into a confidentiality agreement reasonably acceptable to ABIOMED, provide the Holder and its representatives the opportunity to conduct a reasonable inquiry of ABIOMED's financial and other records during normal business hours and make available its officers, directors and employees for questions regarding information which the Holder may reasonably request in order to fulfill any due diligence obligation on its part.

(j) Permit counsel for the Holder to review such registration statement and all amendments and supplements thereto a reasonable period of time prior to the filing thereof with the SEC.

(k) In the event of an underwritten public offering of the Shares, enter into and perform its obligations under an underwriting agreement, in usual and customary form reasonably acceptable to ABIOMED, with the

16

underwriters of such offering and to use its best efforts to cause the conditions to the underwriters' performance thereunder to be met.

7.6. Description of Expenses.

All expenses incurred by ABIOMED in complying with any of the foregoing provisions of this Section 7, including without limitation all federal and state registration, qualification and filing fees, printing expenses, fees and disbursements of counsel to ABIOMED, and accountants' fees and expenses incident to or required by any such registration are herein called "Registration Expenses." All underwriting discounts and selling commissions applicable to the sale of Shares hereunder and the fees and disbursements of one counsel to the Holders with respect to any registration of the Shares hereunder are herein called "Selling Expenses." If ABIOMED is required by the provisions of this Article 7 to use commercially reasonable efforts to effect the registration of any of the Shares under the Securities Act, the Registration Expenses and Selling Expenses in connection with such registration shall be borne as follows:

(a) All Registration Expenses shall be borne by ABIOMED.

(b) Selling Expenses shall be borne pro rata among the Holders participating in the registration, except that each Holder shall bear the expenses of any separate counsel retained by it.

7.7. Indemnification.

In the event that ABIOMED registers under the Securities Act any Shares held by a Holder:

(a) ABIOMED agrees to indemnify and hold harmless such Holder, each person, if any, who controls such Holder within the meaning of the Securities Act, any Underwriter offering or selling the Holder's Shares and any person controlling such Underwriter, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading, unless such statement or omission was (i) made in reliance upon information furnished in writing by any such Holder, Underwriter or controlling person specifically for inclusion therein or (ii) contained in a preliminary prospectus and corrected in a final or amended prospectus if such Holder, Underwriter or controlling person received notice of such final or amended prospectus prior to the effective date of the registration statement but failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Shares to the person asserting such loss, claim, damage or liability, in any case where such delivery is required by the Securities Act.

17

(b) The obligations of ABIOMED under Sections 7.2 and 7.3 with respect to any Holder are subject to the following conditions:
(i) that each Holder whose Shares are to be included in any registration referred to in this Article 7 agrees, in writing, prior to the filing of such registration or filing, to indemnify and hold harmless ABIOMED and each person, if any, who controls ABIOMED within the meaning of the Securities Act, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein not misleading, but only with reference to statements or omissions made in reliance upon a statement in writing furnished by or on behalf of such Holder for inclusion therein; provided, however, that the liability of each Holder to so indemnify shall be limited to the amount received by such Holder on the sale of his or her Shares pursuant to such registration statement, and (ii) if such registration relates to an underwritten public offering by ABIOMED, that each such Holder enters into an underwriting agreement in usual and standard form (including a "lock-up" not exceeding 180 days of Shares not being sold in the underwritten offering) respecting such offering and uses its best reasonable efforts to cause the conditions to the Underwriters' performance thereunder to be met.

(c) Each Party entitled to indemnification under this Section 7.7 (the "Indemnified Party") shall give notice to the party required to provide indemnification (the "Indemnifying Party") promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom; provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld); and, provided, further, that the failure of any Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Section 7.7 unless and to the extent that such failure results in the forfeiture of substantive rights or defenses by the Indemnifying Party. The Indemnified Party may participate in such defense at such party's expense; provided, however, that the Indemnifying Party shall pay such expense if, in the opinion of counsel to the Indemnified Party, representation of such Indemnified Party by the counsel retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between the Indemnified Party and any other party represented by such counsel. No Indemnifying Party, in the defense of any such claim or litigation shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement that does not include

18

as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect of such claim or litigation and the Indemnifying Party shall not be required to indemnify any Indemnified Party for any amount paid or payable by such Indemnified Party in settlement of any claim or litigation without such consent of the Indemnifying Party, which consent shall not be unreasonable withheld.

ARTICLE 8. CONFIDENTIALITY

In connection with the due diligence investigation of ABIOMED by Genzyme and Genzyme's status as a substantial stockholder of ABIOMED and in the course of discussing projects in the field of minimally invasive cardiac surgery that the Parties may jointly develop, fund and commercialize, the Parties acknowledge that they have been or may be given access to confidential information of the other Party. For purposes of this Agreement, the term "Confidential Information" means any information relating to the scientific and business affairs of either Party, regardless of whether such information is specifically designated as confidential and regardless of whether such information is in written, oral, electronic, or other form. Such Confidential Information may include, without limitation, trade secrets, know-how, inventions, technical data or specifications, testing methods, business or financial information, research and development activities, product and marketing plans, and customer and supplier information.

8.1. Non-Disclosure Obligations.

With respect to all Confidential Information furnished by one party (the "Disclosing Party") to the other (the "Receiving Party"), the Receiving Party agrees that it shall:

(a) maintain such Confidential Information in strict confidence, at least to the same extent as the Receiving Party maintains the confidence of its own information of like nature;

(b) not disclose or permit the disclosure of such Confidential Information to any persons other than to its directors, officers, employees, agents, consultants and service providers who need to know such Confidential Information and who are obligated to maintain the confidential nature of such Confidential Information;

(c) use such Confidential Information only for purposes related to the ongoing business relationship between the Parties and not use any Confidential Information for its own benefit or for the benefit of any other person or business entity; and

(d) allow its directors, officers, employees, agents, and other representatives to reproduce the Confidential Information only to the extent necessary to effect the purposes set forth herein, with all such reproductions being considered Confidential Information.

19

8.2. Exceptions to Non-Disclosure Obligations.

The obligations of the Receiving Party under Section 8.1 above shall not apply to the extent that the Receiving Party can demonstrate (with the Receiving Party having the burden of proof) that certain Confidential Information:

(a) was in the public domain prior to the time of its disclosure;

(b) entered the public domain after the time of its disclosure through means other than an unauthorized disclosure resulting from an act or omission by the Receiving Party;

(c) was independently developed or discovered by the Receiving Party without use of the Confidential Information;

(d) is or was disclosed to the Receiving Party at any time, whether prior to or after the time of its disclosure under this Agreement, by a third party having no obligation of confidentiality with respect to such Confidential Information; or

(e) is required to be disclosed to comply with applicable laws or regulations, or with a court or administrative order, provided that the Disclosing Party receives prior written notice of such disclosure to permit it to seek a protective order against such disclosure, and in the absence of such protective order, that the Receiving Party takes all reasonable and lawful actions to obtain confidential treatment for such disclosure and, if possible, to minimize the extent of such disclosure.

8.3. Ownership of Confidential Information.

The Receiving Party agrees that the Disclosing Party (or any third party entrusting its own Confidential Information to the Disclosing Party) is and shall remain the exclusive owner of the Confidential Information disclosed by the Disclosing Party and all patent, copyright, trademark, trade secret, and other intellectual property rights in such Confidential Information or arising therefrom. No option, license, or conveyance of such rights to the Receiving Party is granted or implied under this Agreement. If any such rights are to be granted to the Receiving Party, such grant shall be expressly set forth in a separate written instrument.

8.4. Destruction of Confidential Information.

Upon the later of (a) transfer of all of the Shares or (b) the termination by either Party of any ensuing business arrangement between the Parties that is conducted without the benefit of a further agreement governing the treatment of Confidential Information, the Receiving Party shall return to the Disclosing Party all originals, copies, and summaries of documents, materials, and other tangible manifestations of Confidential Information in any form or media, including formal and informal notes and memoranda, in the possession or control of the Receiving Party, except

20

that the Receiving Party may retain one copy of such Confidential Information in the possession of its legal counsel solely for the purpose of monitoring its obligations under this Agreement.

8.5. Material Inside Information.

The Receiving Party further acknowledges that it may receive material inside information regarding the Disclosing Party that has not been generally disclosed to the public in the course of its investigation and agrees to treat such information as Confidential Information. The Receiving Party further understands that if it receives such material inside information, it may not trade, directly or indirectly, in the securities of the Disclosing Party until such time as such information is no longer material or is otherwise disclosed to the public.

8.6. Terms of this Agreement.

The Parties agree that the public announcement of the execution of this Agreement shall take the form of a press release mutually agreeable to the Parties and, from and after the date hereof, each Party shall be entitled to make or publish any statement limited to the contents of such press release. Except as permitted by the foregoing provisions, each Party hereby agrees not to disclose any terms or conditions of this Agreement to any third party without the prior consent of the other Party; provided, however, that each Party will give the other Party the opportunity to review and comment on any disclosure that may be required by law.

ARTICLE 9. JOINT DEVELOPMENT AND COLLABORATIONS

ABIOMED and Genzyme shall continue to attempt diligently to identify projects in the field of minimally invasive cardiac surgery that the Parties can jointly develop, fund and commercialize.

ARTICLE 10. MISCELLANEOUS

10.1. Assignment.

This Agreement may not be assigned or otherwise transferred by any Party without the consent of the other Party, which consent shall not be unreasonably withheld. Notwithstanding the foregoing, Genzyme's rights under Article 7 shall inure to the benefit of each Holder (as defined in Section 7.1) of the Shares. Any purported assignment in violation of this Section 10.1 shall be void. Any permitted assignee shall assume all obligations of its assignor under this Agreement in writing.

10.2 Severability.

Each Party hereby agrees that it does not intend to violate any public policy, statutory or common laws, rules, regulations, treaty or decision of any government agency or executive body thereof of any country or community or association of countries. Should one or more provisions of this Agreement be or become invalid, the Parties hereto shall substitute, by mutual consent, valid provisions for such invalid provisions, which valid provisions in their economic effect are

21

sufficiently similar to the invalid provisions that it can be reasonably assumed that the Parties would have entered into this Agreement with such valid provisions. In case such valid provisions cannot be agreed upon, the invalidity of one or several provisions of this Agreement shall not affect the validity of this Agreement as a whole, unless the invalid provisions are of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without the invalid provisions.

10.3. Notices.

Any consent, notice or report required or permitted to be given or made under this Agreement by one of the Parties hereto to the other shall be in writing, delivered personally or by facsimile (and promptly confirmed by personal delivery or courier) or courier, postage prepaid (where applicable), addressed to such other Party at its address indicated below, or to such other address as the addressee shall have last furnished in writing to the addressor in accordance with this Section 10.3, and shall be effective upon receipt by the addressee.

If to                    ABIOMED, Inc.

ABIOMED                  33 Cherry Hill Drive
                         Danvers, Massachusetts 01923
                         Attention: President
                         Facsimile: (508) 777-8411

with a copy to:          Brown Rudnick Freed & Gesmer, P.C.
                         One Financial Center
                         Boston, Massachusetts 02111
                         Attention: Philip J. Flink, Esq.
                         Facsimile: (617) 856-8201

If to                    Genzyme Corporation
Genzyme:                 One Kendall Square
                         Cambridge, Massachusetts 02139
                         Attention: President
                         Facsimile: (617) 374-7423

with a copy to:          Genzyme Corporation
                         One Kendall Square
                         Cambridge, Massachusetts 02139
                         Attention: Chief Legal Counsel
                         Facsimile: (617) 252-7553

10.4. Applicable Law.

This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts.

10.5. Entire Agreement.

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This Agreement contains the entire understanding of the Parties with respect to the subject matter hereof. All express or implied agreements and understandings, either oral or written, heretofore made are expressly merged in and made a part of this Agreement. This Agreement may be amended, or any term hereof modified, only by a written instrument duly executed by the Parties. Each of the Parties hereby acknowledges that this Agreement is the result of mutual negotiation and therefore any ambiguity in their respective terms shall not be construed against the drafting Party.

10.6. Headings.

The captions to the several Articles and Sections hereof are not a part of this Agreement, but are merely guides or labels to assist in locating and reading the several Articles and Sections hereof.

10.7. Counterparts.

This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first set forth above.

ABIOMED, INC.

By:/s/ David M. Lederman
   -----------------------------------------

Title:______________________________________
      President and Chief Executive Officer

GENZYME CORPORATION

By:/s/ Peter Wirth
   -----------------------------------
       Peter Wirth

Title:________________________________
      Executive Vice President

23

Exhibit 99.3

COMMON STOCK PURCHASE AGREEMENT

between

ABIOMED, Inc.

and

Paul Fireman

dated as of July 14, 1997


TABLE OF CONTENTS

ARTICLE 1. PURCHASE AND SALE OF SHARES.....................  1
 1.1. Authorization........................................  1
      -------------
 1.2. Purchase and Sale of the Shares......................  1
      -------------------------------
 1.3. Delivery of Certificates.............................  1
      ------------------------
 1.4. Simultaneous Lederman Purchase and Sale..............  1
      ---------------------------------------

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED.......  2
 2.1. Organization and Qualification.......................  2
      ------------------------------
 2.2. Capitalization.......................................  2
      --------------
 2.3. Issuance and Sale of Shares..........................  3
      ---------------------------
 2.4. Authority for Agreement..............................  3
      -----------------------
 2.5. SEC Reports..........................................  3
      -----------
 2.6. Financial Statements.................................  3
      --------------------
 2.7. Subsidiaries.........................................  4
      ------------
 2.8. Absence of Undisclosed ABIOMED Liabilities...........  4
      ------------------------------------------
 2.9. No Material Adverse Change...........................  4
      --------------------------
 2.10. Tax Matters.........................................  5
       -----------
 2.11. No Breach...........................................  5
       ---------
 2.12. Actions and Proceedings.............................  6
       -----------------------
 2.13. Compliance with Laws................................  6
       --------------------
 2.14. Brokerage...........................................  6
       ---------

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR..  6
 3.1. Authority for Agreement..............................  6
      -----------------------
 3.2. Investment...........................................  7
      ----------
 3.3. Restrictions on Transferability; Legend..............  7
      ---------------------------------------
 3.4. Information..........................................  7
      -----------
 3.5. Brokerage............................................  7
      ---------

ARTICLE 4. REGISTRATION RIGHTS.............................  8
 4.1. Certain Definitions..................................  8
      -------------------
 4.2. Required Registration................................  8
      ---------------------
 4.3. Conditions of Obligations to Register Shares.........  9
      --------------------------------------------
 4.4. Registration Procedures..............................  9
      -----------------------
 4.5. Description of Expenses..............................  11
      -----------------------
 4.6. Indemnification......................................  12
      ---------------

ARTICLE 5. MISCELLANEOUS...................................  13
 5.1. Assignment...........................................  13
      ----------
 5.2. Severability.........................................  13
      ------------
 5.3. Notices..............................................  14
      -------
 5.4. Applicable Law.......................................  14
      --------------
 5.5. Entire Agreement.....................................  14
      ----------------

(i)

5.6. Headings.............................................  15
5.7. Counterparts.........................................  15

(ii)

COMMON STOCK PURCHASE AGREEMENT

THIS COMMON STOCK PURCHASE AGREEMENT dated as of July 14, 1997 (the "Agreement") is between ABIOMED, Inc., a Delaware corporation having its principal place of business at 33 Cherry Hill Drive, Danvers, Massachusetts 01923 (ABIOMED"), and Paul Fireman of ______________, Massachusetts (the "Investor"). ABIOMED and the Investor are sometimes referred to herein individually as a "Party" and collectively as the "Parties."

In consideration of the mutual promises and of the covenants contained herein, the Parties hereby agree as follows:

ARTICLE 1. PURCHASE AND SALE OF SHARES

1.1. Authorization.

ABIOMED has duly authorized the issuance and sale to the Investor of Twenty- Three Thousand Four Hundred Eighty (23,480) shares (the "Shares") of its Common Stock, $0.01 par value per share ("Common Stock").

1.2. Purchase and Sale of the Shares.

Concurrently with the execution and delivery of this Agreement, ABIOMED hereby issues and sells to the Investor, and the Investor hereby purchases from ABIOMED, the Shares at a purchase price of $13.00 per Share, for an aggregate purchase price of Three Hundred Five Thousand Two Hundred Forty Dollars ($305,240.00). The purchase price shall be payable by the Investor to ABIOMED upon execution of this Agreement.

1.3. Delivery of Certificates.

On the date hereof, ABIOMED will deliver to the Investor one or more certificates representing the Shares registered in the name of the Investor against payment by the Investor of the purchase price by check or wire transfer.

1.4. Simultaneous Lederman Purchase and Sale.

Reference is made to and the Parties hereby acknowledge that certain Common Stock Purchase Agreement (the "Lederman Agreement") dated as of the date hereof by and between David M. Lederman ("Lederman") and the Investor pursuant to which Lederman is selling and transferring to the Investor and the Investor is purchasing from Lederman an aggregate of One Hundred Fifty-Three Thousand Eight Hundred Forty Six (153,846) shares of Common Stock (the "Lederman Shares") simultaneously with the purchase and sale contemplated by this Agreement. ABIOMED acknowledges that the Investor is relying upon the representations and warranties of ABIOMED set forth in Article 2 hereof in connection with the Investor's execution and delivery of the Lederman Agreement.

1

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED

Except as otherwise set forth in the disclosure schedule delivered to the Investor on the date hereof (the "Disclosure Schedule"), the section numbers of which are numbered to correspond to the sections of this Agreement to which they refer, ABIOMED represents and warrants to the Investor as follows:

2.1. Organization and Qualification.

Each of ABIOMED and the Subsidiaries (as defined in Section 2.7) is a corporation or partnership duly organized, validly existing and in good standing under the laws of its state or jurisdiction of incorporation or formation with full power and authority to own, lease and operate its assets, properties and business and to carry on its business as now being and as heretofore conducted. Each of ABIOMED and the Subsidiaries is qualified or otherwise authorized to transact business as a foreign corporation or partnership in all jurisdictions in which such qualification or authorization is required by law, except for jurisdictions in which the failure to so qualify or be authorized would not have a material adverse effect on the assets, properties, business, operations or condition (financial or otherwise) of ABIOMED and the Subsidiaries taken as a whole (the "Business of ABIOMED").

2.2. Capitalization.

(a) ABIOMED is authorized to issue 25,000,000 shares of Common Stock, of which 7,017,872 shares were issued and outstanding as of June 30, 1997, 2,346,000 shares of Class A Common Stock, $0.01 par value per share, none of which are issued and outstanding, 150,000 shares of Class A Preferred Stock, $0.01 par value per share, none of which are issued and outstanding and 1,000,000 shares of Class B Preferred Stock, $0.01 par value per share, none of which are issued and outstanding. No other class of capital stock of ABIOMED is authorized or outstanding. All of the issued and outstanding shares of ABIOMED's capital stock are duly authorized and are validly issued, fully paid, nonassessable and free of preemptive rights. None of the issued and outstanding shares have been issued in violation of any federal or state law except for violations that would not have a material adverse effect on the Business of ABIOMED.

(b) Options representing in the aggregate the right to purchase 969,785 shares of Common Stock pursuant to ABIOMED's 1992 Combination Stock Option Plan and ABIOMED's 1989 Non-Qualified Stock Option Plan for Non-Employee Directors are outstanding as of the date hereof.

(c) 90,718 shares of Common Stock are reserved for issuance under ABIOMED's 1988 Employee Stock Purchase Plan as of the date hereof.

(d) Except as set forth in paragraphs (a), (b) and (c) of this
Section 2.2, Section 2.2 of the Disclosure Schedule or as a result of the exercise of outstanding options or rights set forth therein, there are not, as of the date hereof, any other shares of ABIOMED capital stock authorized or outstanding or any subscriptions, options, conversion or exchange rights,

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warrants, repurchase or redemption agreements, or other agreements or commitments obligating ABIOMED to issue, transfer, sell, repurchase or redeem any shares of its capital stock or other securities of ABIOMED. To the best knowledge of ABIOMED, there are no written stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the voting of the capital stock of ABIOMED.

2.3. Issuance and Sale of Shares.

The issuance and sale of the Shares by ABIOMED has been duly authorized and the Shares have been duly reserved for issuance by all necessary corporate action on the part of ABIOMED, and the Shares, when issued and delivered against payment therefor, will be duly and validly issued, fully paid and non- assessable. Based in part on the representations made by the Investor set forth in Article 3 below, the offer, issuance and sale of the Shares pursuant to this Agreement are exempt from registration under the Securities Act of 1933, as amended (the "Securities Act"), and applicable state securities laws. ABIOMED has complied with all applicable federal and state securities laws and with the Nasdaq By-Laws in connection with the offer, issuance and sale of the Shares.

2.4. Authority for Agreement.

The execution, delivery and performance by ABIOMED of this Agreement has been duly authorized by all necessary corporate action, and this Agreement has been duly executed and delivered by ABIOMED. This Agreement constitutes the valid and binding obligation of ABIOMED enforceable against ABIOMED in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

2.5. SEC Reports.

ABIOMED has previously delivered to the Investor its (a) Annual Report on Form 10-K for the year ended March 31, 1997 (the "ABIOMED 10-K"), as filed with the Securities and Exchange Commission (the "SEC'), (b) all proxy statements relating to ABIOMED's meetings of stockholders held or currently scheduled to be held since March 31, 1997 and (c) all other reports filed by ABIOMED with the SEC under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), since March 31, 1997. As of their respective dates, such reports complied in all material respects with applicable SEC requirements and did not contain any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading. ABIOMED has timely filed with the SEC all reports required to be flied under Section 13, 14 or 15(d) of the Exchange Act since March 31, 1997.

2.6. Financial Statements.

The financial statements contained in the ABIOMED 10-K have been prepared from, and are in accordance with, the books and records of ABIOMED and present fairly, in all material respects, the financial condition and results of operations of ABIOMED as of and for the periods

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presented therein, all in conformity with United States generally accepted accounting principles, consistently applied, except as otherwise noted therein.

2.7. Subsidiaries.

(a) The Disclosure Schedule sets forth all of the Subsidiaries and the jurisdiction in which each is incorporated or organized. Except as set forth on the Disclosure Schedule, all issued and outstanding shares or partnership interests of each Subsidiary are owned directly by ABIOMED free and clear of any charges, liens, encumbrances, security interests or adverse claims. As used in this Agreement, "Subsidiary" means any corporation, partnership or other legal entity of which ABIOMED or any Subsidiary owns, directly or indirectly, 50% or more of the stock or other equity interest entitled to vote for the election of directors.

(b) Except as set forth on the Disclosure Schedule, there are not as of the date hereof any other shares of capital stock or other equity interest of any Subsidiary authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements, claims or commitments of any nature whatsoever obligating any Subsidiary to issue, transfer, deliver, sell, repurchase or redeem any shares of the capital stock or other equity interest of any Subsidiary or obligating ABIOMED or any Subsidiary to grant, extend or enter into any such agreement. To the best knowledge of ABIOMED, there are no stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the capital stock of any Subsidiary.

(c) Except for the Subsidiaries, ABIOMED does not directly or indirectly own or have any investment in any of the capital stock of, and is not a party to a partnership or joint venture with, any other person.

2.8. Absence of Undisclosed ABIOMED Liabilities.

As of March 31, 1997, ABIOMED and the Subsidiaries had no material liabilities of any nature, whether accrued, absolute, contingent or otherwise,
(a) required to be reflected or disclosed on the balance sheets dated March 31, 1997 (or the notes thereto) included in the ABIOMED 10-K that in the opinion of management were not adequately reflected or reserved against on such balance sheets or (b) for the payment of any dividends, or any other distribution, to the stockholders of ABIOMED. ABIOMED and the Subsidiaries have no such liabilities, other than liabilities (i) which in the opinion of management as of March 31, 1987 are adequately reflected or reserved against on such balance sheet, (ii) incurred since March 31, 1997 in the ordinary course of business and consistent with past practice or (iii) that would not, in the aggregate, have a material adverse effect on the Business of ABIOMED.

2.9. No Material Adverse Change.

Since March 31, 1997, there has not been any material adverse change in the Business of ABIOMED.

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2.10. Tax Matters.

(a) ABIOMED and each of the Subsidiaries have filed all tax reports and returns required to be filed by them and have paid or will timely pay all taxes and other charges shown as due on such reports and returns. Neither ABIOMED nor any of the Subsidiaries is delinquent in the payment of any material tax assessment or other governmental charge (including without limitation applicable withholding taxes). Any provision for taxes reflected in the financial statements referenced in Section 2.6 above is, to the best knowledge of ABIOMED, adequate for payment of any and all tax liabilities for periods ending on or before March 31, 1997 and there are no tax liens on any assets of ABIOMED or the Subsidiaries except liens for current taxes not yet due.

(b) Except as set forth in Section 2.10 of the Disclosure Schedule, there has not been any audit of any tax return filed by ABIOMED or any of the Subsidiaries and no audit of any such tax return is in progress and neither ABIOMED nor any Subsidiary has been notified by any tax authority that any such audit is contemplated or pending. ABIOMED knows of no material tax deficiency or claim for additional taxes asserted or threatened to be asserted against ABIOMED or any of the Subsidiaries by any taxing authority and ABIOMED knows of no grounds for any such assessment. No extension of time with respect to any date on which a tax return was or is to be filed by ABIOMED or any of the Subsidiaries is in force, and no waiver or agreement by ABIOMED or any of the Subsidiaries is in force for the extension of time for the assessment or payment of any tax. For purposes of this Agreement, the term "tax" includes all federal, state, local and foreign taxes or assessments, including income, sales, gross receipts, excise, use, value added, royalty, franchise, payroll, withholding, property and import taxes and any interest or penalties applicable thereto.

2.11. No Breach.

The execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby will not: (a) violate any provision of the certificate of incorporation or by-laws of ABIOMED; (b) violate, conflict with or result in the breach of any of the terms or conditions of, result in modification of the effect of, or otherwise give any other contracting party the right to terminate, or constitute (or with notice or lapse of time or both constitute) a default under, any material instrument, contract or other agreement to which ABIOMED or any of the Subsidiaries is a party or to which any of the assets or properties of ABIOMED or any of the Subsidiaries may be bound or subject; (c) violate any order, judgment, injunction, award or decree of any court, arbitrator or governmental or regulatory body against, or binding upon, ABIOMED, any Subsidiary or upon any of their respective securities, properties, assets or businesses; (d) violate any statute, law or regulation of any jurisdiction as such statute, law or regulation relates to ABIOMED, any Subsidiary or any of their respective securities, properties, assets or businesses; (e) require the approval, consent or authorization of, or registration or filing with, any foreign, federal, state, local or other governmental or regulatory body or the approval, consent, waiver or notification of any stockholder, creditor, lessor or other person; or (f) result in the creation of any lien or other encumbrance on the assets or properties of ABIOMED or any of the Subsidiaries, excluding from clauses (b) - (f') such matters as would not

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in the aggregate have a material adverse effect on the Business of ABIOMED or upon the transactions contemplated hereby.

2.12. Actions and Proceedings.

There are no outstanding orders, judgments, injunctions, awards or decrees of any court, governmental or regulatory body or arbitration tribunal against ABIOMED, any Subsidiary or any of their respective properties or assets. There are no actions, suits or claims or legal, administrative or arbitral proceedings or, to the best knowledge of ABIOMED, investigations (whether or not the defense thereof or liabilities in respect thereof are covered by insurance) pending or, to the best knowledge of ABIOMED, threatened against ABIOMED, any Subsidiary or any of their respective properties or assets.

2.13. Compliance with Laws.

To its knowledge, neither ABIOMED nor any of the Subsidiaries is in violation of any statute, law, rule or regulation, or in default with respect to any judgment, writ, injunction, decree, rule or regulation of any court, governmental or regulatory body or arbitration tribunal, including without limitation laws relating to environmental protection, health and safety matters and labor and employment practices, except for such violations or defaults which do not, individually or in the aggregate, materially and adversely affect the Business of ABIOMED.

2.14 Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of ABIOMED in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with ABIOMED or any action taken by ABIOMED, other than a fee payable by ABIOMED to UBS Securities LLC in connection with a fairness opinion being rendered by UBS Securities LLC.

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR

The Investor hereby represents and warrants to ABIOMED as follows:

3.1. Authority for Agreement.

The Investor has the power and authority to execute and deliver this Agreement and to perform all of his obligations hereunder. This Agreement has been duly executed and delivered by the Investor. This Agreement constitutes the valid and binding obligation of the Investor enforceable against the Investor in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

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3.2. Investment.

The Investor is an accredited investor, as defined in Rule 501 of Regulation D under the Securities Act. The Investor is acquiring the Shares solely for his own account for investment purposes as a principal and not with a view to the public resale or distribution of all or any part thereof; provided however, that in making such representation, the Investor does not agree to hold the Shares for any minimum or specific term and reserves the right to sell, transfer or otherwise dispose of the Shares at any time in accordance with the terms of this Agreement and with federal and state securities laws applicable to such sale, transfer or disposition.

3.3. Restrictions on Transferability; Legend.

The Investor understands that the Shares have not been registered under the Securities Act or under the securities laws of any state or other jurisdiction in reliance upon exemptions thereunder. The Investor acknowledges and is aware that the Shares cannot be resold unless the Shares are registered under the Securities Act and any applicable securities law of any state or other jurisdiction, or an exemption from registration is available. Each certificate representing the Shares shall bear a legend in substantially the following form (unless such Shares have been transferred pursuant to a registration statement under the Securities Act or, in the opinion of counsel acceptable to ABIOMED, such a legend is not required):

THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR ANY STATE SECURITIES LAW AND MAY NOT BE TRANSFERRED EXCEPT (i) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT OR (ii) UPON FIRST FURNISHING TO THE COMPANY AN OPINION OF COUNSEL SATISFACTORY TO IT THAT SUCH TRANSFER IS NOT IN VIOLATION OF THE REGISTRATION REQUIREMENTS OF THE ACT OR ANY STATE SECURITIES LAW.

3.4. Information.

The Investor has reviewed (a) the representations of ABIOMED contained in this Agreement and (b) the ABIOMED 10-K and has had the opportunity to make inquiry concerning ABIOMED and its business and personnel. The Investor is a director of ABIOMED and in such capacity is otherwise familiar with the business of ABIOMED. The officers of ABIOMED have made available to the Investor any and all written information that he has requested and have answered to the Investor's satisfaction all inquiries made by the Investor.

3.5. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of the Investor in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with the Investor, or any action taken by him.

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ARTICLE 4. REGISTRATION RIGHTS

4.1. Certain Definitions.

As used in this Article 4, the following terms shall have the following respective meanings:

(a) "Holders" shall mean the Investor and any of his successors and assigns (other than successors and assigns who acquire the Shares pursuant to a registered public offering or pursuant to a transaction covered by Rule 144 under the Securities Act) who hold Shares.

(b) "Registration Expenses" and "Selling Expenses" shall mean the expenses so described in Section 4.6.

(c) "Other Holders" shall mean all holders of the Company's securities other than Holders.

(d) "Shares" for purposes of this Article 5 shall have the meaning set forth in Section 1.1 hereof, with the exception that the term shall not include Shares which at any time have become salable pursuant to Rule 144(k) promulgated by the SEC pursuant to the Securities Act, or any similar successor rule

(e) "Underwriter" shall mean each person who is or may be deemed an "underwriter," as that term is defined in Section 2(11) of the Securities Act, in respect of securities which shall have been registered by ABIOMED under the Securities Act pursuant to any of the provisions of this Article 6.

4.2. Required Registration.

If ABIOMED for itself or any of its security holders shall at any time or times after the first anniversary of the date hereof and prior to the seventh anniversary of the date hereof determine to register under the Securities Act any shares of Common Stock for an underwritten public offering other than (a) the registration of an offer and sale of securities to employees of, or other persons providing services to ABIOMED pursuant to an employee or similar benefit plan, registered on Form S-8 or comparable form; or (b) relating to a merger, acquisition or other transaction of the type described in Rule 145 under the Securities Act or comparable rule, registered on Form S-4 or similar form, ABIOMED will notify each Holder in each case of such determination at least ten
(10) days prior to the filing of such registration statement, and upon the request of a Holder given in writing within five days after the date of such notice, ABIOMED will use commercially reasonable efforts as soon as practicable thereafter to cause any of the Shares specified by such Holder to be included in such registration statement. Notwithstanding the foregoing, if the managing underwriter determines and advises in writing that the inclusion of all Shares of such requesting Holders and all shares of ABIOMED's Common Stock to be offered by ABIOMED and by Other Holders, whether covered by requests for registration or otherwise included, would interfere with the marketing of the securities to be sold by ABIOMED, or if the registration is at the request of a person or persons with a right to require registration, by that person or persons; then the number of shares of Common Stock otherwise to be included in the

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registration statement by Holders and Other Holders shall be reduced as follows:
(i) there shall first be excluded shares proposed to be included by Other Holders not possessing legal rights to include the same pursuant to this section or any similar provision; and (ii) any further reduction shall be pro rata among such Holders and Other Holders (having such legal rights) in proportion to the number of shares as to which registration is requested by each; provided however, that there shall be no reduction in the number of shares to be included therein (x) by ABIOMED or (y) if the registration is at the request of a person or persons with a right to require such registration, by that person or persons. For purposes of making any such reduction, each holder (whether a Holder or Other Holder) which is a partnership, together with the affiliates, partners and retired partners of such holder, the estates and family members of any such partners and retired partners and of their spouses, and any trusts for the benefit of any of the foregoing persons shall be deemed to be a single holder and any pro rata reduction with respect to such holder shall be based upon the aggregate amount of Shares sought to be sold by all entities and individuals so included in such holder, and the aggregate reduction so allocated to such holder shall be allocated among the entities and individuals included in such holder in such manner as such partnership may reasonably determine. If the managing underwriter determines and advises in writing that the inclusion in the registration statement of any shares of Common Stock to be sold by stockholders of ABIOMED would interfere with the marketing of the securities to be sold by ABIOMED, no notice need be given to any Holder pursuant to the first sentence of this section and no Holder will have the right to include its Shares in such registration statement.

4.3. Conditions of Obligations to Register Shares.

As conditions to ABIOMED's obligation hereunder to cause Shares to be included in a registration statement, the Holder shall provide such information and execute such documents as may reasonably be required in connection with such registration.

4.4. Registration Procedures.

If and whenever ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to include any of the Shares in a registration statement filed under the Securities Act, ABIOMED shall as expeditiously as possible:

(a) Prepare and file with the SEC a registration statement with respect to such Shares and use commercially reasonable efforts to cause such registration statement to become effective.

(b) Prepare and file with the SEC such amendments and supplements to such registration statement and the prospectus used in connection therewith as may be necessary to keep such registration statement effective until the Shares covered thereunder have been sold.

(c) Secure the designation and quotation of the Shares on Nasdaq or any national securities exchange on which the Common Stock is then listed.

(d) Furnish to each Holder such number of copies of the prospectus contained in such registration statement (including each preliminary prospectus), in conformity with the

9

requirements of the Securities Act, and such other documents as such Holder may reasonably request in order to facilitate the disposition of the Shares owned by such Holder:

(e) Use commercially reasonable efforts to register or qualify the Shares covered by such registration statement under the securities or "blue sky" laws of such jurisdictions as each selling Holder shall reasonably request, and do any and all other acts and things which may be reasonably necessary or advisable to enable such Holder to consummate the disposition of the Shares owned by such Holder in such jurisdictions during the period specified in
Section 4.4(b), provided that ABIOMED shall not be required in connection herewith to execute a general consent to service of process in any jurisdiction.

(f) Notify each Holder immediately of any Shares covered by such registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus contained in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state any material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing, and as promptly as practicable, prepare, file and furnish to the Holder a reasonable number of copies of a supplement or an amendment to such prospectus as may be necessary so that such prospectus does not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing; provided however, that ABIOMED may delay preparing, filing and distributing any such supplement or amendment if ABIOMED determines in good faith that such supplement or amendment might, in the reasonable judgment of ABIOMED (i) interfere with or affect the negotiation or completion of a transaction that is being contemplated by ABIOMED (whether or not a final decision has been made to undertake such transaction) or (ii) involve initial or continuing disclosure obligations that are not in the best interests of ABIOMED's stockholders at such time; provided, further, that (x) ABIOMED will give notice (a "Standstill Notice") of any such delay no less than five (5) business days prior to such delay, (y) such delay shall not extend for a period of more than fifteen (15) business days without the written consent of the Holder and (z) ABIOMED may utilize such delay no more than once in each calendar year. Each Holder agrees, upon receipt of a Standstill Notice, forthwith to cease making offers and sales of the Shares pursuant to the registration statement or deliveries of the prospectus contained therein and to return to ABIOMED, for modification and exchange, the copies of such prospectus not theretofore delivered by such Holder; provided that ABIOMED shall forthwith prepare and deliver to such Holder after such delay a reasonable number of copies of any supplement to or amendment of such prospectus that may be necessary so that such prospectus does not include an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing.

(g) Use commercially reasonable efforts to prevent the issuance of any stop order or other order suspending the effectiveness of such registration statement and, if such an order is issued, to obtain the withdrawal at the earliest possible time and to notify the Holder of the issuance of such order and the resolution thereof.

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(h) Furnish to the Holder and the Underwriter of the Holder's Shares, on the date that such registration statement becomes effective, (i) an opinion, dated such date, of outside counsel representing ABIOMED (and reasonably acceptable to the Holder) addressed to the Holder as to the effectiveness of the registration statement and its compliance as to form with the requirements of the Securities Act and such other matters as may be reasonably requested by the Holder (including, such additional matters as are customarily included in opinions delivered by company counsel in underwritten public offerings) and (ii) a letter, dated such date, from ABIOMED's independent certified public accountants, in form and substance as is customarily given by independent certified public accounts to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holder.

(i) Subject to the Holder entering into a confidentiality agreement reasonably acceptable to ABIOMED, provide the Holder and its representatives the opportunity to conduct a reasonable inquiry of ABIOMED's financial and other records during normal business hours and make available its officers, directors and employees for questions regarding information which the Holder may reasonably request in order to fulfill any due diligence obligation on its part.

(j) Permit counsel for the Holder to review such registration statement and all amendments and supplements thereto a reasonable period of time prior to the filing thereof with the SEC.

(k) Enter into and perform its obligations under an underwriting agreement, in usual and customary form reasonably acceptable to ABIOMED, with the underwriters of such offering. and to use its reasonable efforts to cause the conditions to the underwriters' performance thereunder to be met.

Description of Expenses.

All expenses incurred by ABIOMED in complying with any of the foregoing provisions of this Section 4, including without limitation all federal and state registration, qualification and filing fees, printing expenses, fees and disbursements of counsel to ABIOMED, and accountants' fees and expenses incident to or required by any such registration are herein called "Registration Expenses." All underwriting discounts and selling commissions applicable to the sale of Shares hereunder and the fees and disbursements of one counsel to the Holders with respect to any registration of the Shares hereunder are herein called "Selling Expenses." If ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to effect the registration of any of the Shares under the Securities Act, the Registration Expenses and Selling Expenses in connection with such registration shall be borne as follows:

(a) All Registration Expenses shall be borne by ABIOMED.

(b) Selling Expenses shall be borne pro rata among the Holders participating in the registration, except that each Holder shall bear the expenses of any separate counsel retained by it.

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4.6. Indemnification.

In the event that ABIOMED registers under the Securities Act any Shares held by a Holder:

(a) ABIOMED agrees to indemnify and hold harmless such Holder, each person, if any, who controls such Holder within the meaning of the Securities Act, any Underwriter offering or selling the Holder's Shares and any person controlling such Underwriter, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading, unless such statement or omission was (i) made in reliance upon information furnished in writing by any such Holder, Underwriter or controlling person specifically for inclusion therein or (ii) contained in a preliminary prospectus and corrected in a final or amended prospectus if such Holder, Underwriter or controlling person received notice of such final or amended prospectus prior to the effective date of the registration statement but failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Shares to the person asserting such loss, claim, damage or liability, in any case where such delivery is required by the Securities Act.

(b) The obligations of ABIOMED under Section 4.2 with respect to any Holder are subject to the following conditions: (i) that each Holder whose Shares are to be included in any registration referred to in this Article 4 agrees, in writing, prior to the filing of such registration or filing, to indemnify and hold harmless ABIOMED and each person, if any, who controls ABIOMED within the meaning of the Securities Act, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein not misleading, but only with reference to statements or omissions made in reliance upon a statement in writing furnished by or on behalf of such Holder for inclusion therein; provided however, that the liability of each Holder to so indemnify shall be limited to the amount received by such Holder on the sale of his or her Shares pursuant to such registration statement, and (ii) that each such Holder enters into an underwriting agreement in usual and standard form (including a "lock-up" not exceeding 180 days of Shares not being sold in the underwritten offering) respecting such offering and uses its best reasonable efforts to cause the conditions to the Underwriters' performance thereunder to be met .

(c) Each Party entitled to indemnification under this Section
4.6 (the "Indemnified Party") shall give notice to the party required to provide indemnification (the "Indemnifying Party") promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom; provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld); and, provided, further, that the failure of any Indemnified Party to give notice as provided herein shall not

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relieve the Indemnifying Party of its obligations under this Section 4.6 unless and to the extent that such failure results in the forfeiture of substantive rights or' defenses by the Indemnifying Party. The Indemnified Party may participate in such defense at such party's expense; provided, however, that the Indemnifying Party shall pay such expense if, in the opinion of counsel to the Indemnified Party, representation of such Indemnified Party by the counsel retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between the Indemnified Party and any other party represented by such counsel. No Indemnifying Party, in the defense of any such claim or litigation shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement that does not include as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect of such claim or litigation and the Indemnifying Party shall not be required to indemnify any Indemnified Party for any amount paid or payable by such Indemnified Party in settlement of any claim or litigation without such consent of the Indemnifying Party, which consent shall not be unreasonable withheld.

ARTICLE 5. MISCELLANEOUS

5.1. Assignment.

This Agreement may not be assigned or otherwise transferred by any Party without the consent of the other Party; provided, however, that (a) ABIOMED may, without such consent, assign its rights and obligations under this Agreement (i) in connection with a corporate reorganization, to any member of an affiliated group, all or substantially all of the equity interest of which is owned and controlled by ABIOMED or its direct or indirect parent corporation or (ii) in connection with a merger, consolidation or sale of substantially all of ABIOMED'S assets to an unrelated Third Party; provided however, that ABIOMED'S rights and obligations under this Agreement shall be assumed by its successor in interest in any such transaction and shall not be transferred separate from all or substantially all of its other business assets. Any purported assignment in violation of the preceding sentence shall be void. Any permitted assignee shall assume all obligations of its assignor under this Agreement in writing.

5.2. Severability.

Each Party hereby agrees that it does not intend to violate any public policy, statutory or common laws, rules, regulations, treaty or decision of any government agency or executive body thereof of any country or community or association of countries. Should one or more provisions of this Agreement be or become invalid, the Parties hereto shall substitute, by mutual consent, valid provisions for such invalid provisions, which valid provisions in their economic effect are sufficiently similar to the invalid provisions that it can be reasonably assumed that the Parties would have entered into this Agreement with such valid provisions. In case such valid provisions cannot be agreed upon, the invalidity of one or several provisions of this Agreement shall not affect the validity of this Agreement as a whole, unless the invalid provisions are of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without the invalid provisions.

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5.3. Notices.

Any consent, notice or report required or permitted to be given or made under this Agreement by one of the Parties hereto to the other shall be in writing, delivered personally or by facsimile (and promptly confirmed by personal delivery or courier) or courier, postage prepaid (where applicable), addressed to such other Party at its address indicated below, or to such other address as the addressee shall have last furnished in writing to the address or in accordance with this Section 5.3, and shall be effective upon receipt by the addressee.

If to                       ABIOMED, Inc.
ABIOMED:                    33 Cherry Hill Drive
                            Danvers, Massachusetts 01923
                            Attention: President
                            Facsimile: (508) 777-8411

with a copy to:             Brown Rudnick Freed & Gesmer, P.C.
                            One Financial Center
                            Boston, Massachusetts 02111
                            Attention:  Philip J. Flink, Esquire
                            Facsimile: (617) 856-8201

If to                       Paul Fireman
the Investor:               Reebok International, Ltd.
                            100 Technology Center Drive
                            Stoughton, MA  02072
                            Facsimile:  (617) 344-1562

                                 with a copy to:  <6>

5.4. Applicable Law.

This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts.

5.5. Entire Agreement.

This Agreement contains the entire understanding of the Parties with respect to the subject matter hereof. All express or implied agreements and understandings, either oral or written, heretofore made are expressly merged in and made a part of this Agreement. This Agreement may be amended, or any term hereof modified, only by a written instrument duly executed by the Parties. Each of the Parties hereby acknowledges that this Agreement is the result of mutual negotiation and therefore any ambiguity in their respective terms shall not be construed against the drafting Party.

14

5.6. Headings.

The captions to the several Articles and Sections hereof are not a part of this Agreement, but are merely guides or labels to assist in locating and reading the several Articles and Sections hereof.

5.7. Counterparts.

This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first set forth above.

ABIOMED, Inc.

By:_________________________

Title:______________________

/s/ Paul Fireman
----------------------------
Paul Fireman

15

COMMON STOCK PURCHASE AGREEMENT

between

ABIOMED, Inc.

and

John O'Brien

dated as of July 14, 1997


TABLE OF CONTENTS

ARTICLE 1. PURCHASE AND SALE OF SHARES..............................  1
 1.1. Authorization.................................................  1
      -------------
 1.2. Purchase and Sale of the Shares...............................  1
      -------------------------------
 1.3. Delivery of Certificates......................................  1
      ------------------------

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED................  1
 2.1. Organization and Qualification................................  2
      ------------------------------
 2.2. Capitalization................................................  2
      --------------
 2.3. Issuance and Sale of Shares...................................  3
      ---------------------------
 2.4. Authority for Agreement.......................................  3
      -----------------------
 2.5. SEC Reports...................................................  3
      -----------
 2.6. Financial Statements..........................................  3
      --------------------
 2.7. Subsidiaries..................................................  4
      ------------
 2.8. Absence of Undisclosed ABIOMED Liabilities....................  4
      ------------------------------------------
 2.9. No Material Adverse Change....................................  4
      --------------------------
 2.10. Tax Matters..................................................  4
       -----------
 2.11. No Breach....................................................  5
       ---------
 2.12. Actions and Proceedings......................................  6
       -----------------------
 2.13. Compliance with Laws.........................................  6
       --------------------
 2.14. Brokerage....................................................  6
       ---------

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR...........  6
 3.1. Authority for Agreement.......................................  6
      -----------------------
 3.2. Investment....................................................  6
      ----------
 3.3. Restrictions on Transferability; Legend.......................  7
      ---------------------------------------
 3.4. Information...................................................  7
      -----------
 3.5. Brokerage.....................................................  7
      ---------

ARTICLE 4. REGISTRATION RIGHTS......................................  7
 4.1. Certain Definitions...........................................  8
      -------------------
 4.2. Required Registration.........................................  8
      ---------------------
 4.3. Conditions of Obligations to Register Shares..................  9
      --------------------------------------------
 4.4. Registration Procedures.......................................  9
      -----------------------
 4.5. Description of Expenses....................................... 11
      -----------------------
 4.6. Indemnification............................................... 12
      ---------------

ARTICLE 5. MISCELLANEOUS............................................ 14
 5.1. Assignment.................................................... 14
      ----------
 5.2. Severability.................................................. 14
      ------------
 5.3. Notices....................................................... 14
      -------
 5.4. Applicable Law................................................ 15
      --------------
 5.5. Entire Agreement.............................................. 15
      ----------------


5.6. Headings...................................................... 15
     --------
5.7. Counterparts.................................................. 15
     ------------


COMMON STOCK PURCHASE AGREEMENT

THIS COMMON STOCK PURCHASE AGREEMENT dated as of July 14, 1997 (the "Agreement") is between ABIOMED, Inc., a Delaware corporation having its principal place of business at 33 Cherry Hill Drive, Danvers, Massachusetts 01923 (ABIOMED"), and John O'Brien of <2> (the "Investor"). ABIOMED and the Investor are sometimes referred to herein individually as a "Party" and collectively as the "Parties."

In consideration of the mutual promises and of the covenants contained herein, the Parties hereby agree as follows:

ARTICLE 1. PURCHASE AND SALE OF SHARES

1.1. Authorization.

ABIOMED has duly authorized the issuance and sale to the Investor of Fifty-Seven Thousand Six Hundred Ninety-Two (57,692) shares (the "Shares") of its Common Stock, $0.01 par value per share ("Common Stock").

1.2. Purchase and Sale of the Shares.

Concurrently with the execution and delivery of this Agreement, ABIOMED hereby issues and sells to the Investor, and the Investor hereby purchases from ABIOMED, the Shares at a purchase price of $13.00 per Share, for an aggregate purchase price of Seven Hundred Forty-Nine Thousand Nine Hundred Ninety-Six Dollars ($749,996.00). The purchase price shall be payable by the Investor to ABIOMED upon execution of this Agreement.

1.3. Delivery of Certificates.

On the date hereof, ABIOMED will deliver to the Investor one or more certificates representing the Shares registered in the name of the Investor against payment by the Investor of the purchase price by check or wire transfer.

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED

Except as otherwise set forth in the disclosure schedule delivered to the Investor on the date hereof (the "Disclosure Schedule"), the section numbers of which are numbered to correspond to the sections of this Agreement to which they refer, ABIOMED represents and warrants to the Investor as follows:

2.1. Organization and Qualification.

Each of ABIOMED and the Subsidiaries (as defined in Section 2.7) is a corporation or partnership duly organized, validly existing and in good standing under the laws of its state or jurisdiction of incorporation or formation with full power and authority to own, lease and operate its assets, properties and business and to carry on its business as now being and as heretofore conducted. Each of ABIOMED and the Subsidiaries is qualified or otherwise authorized to


transact business as a foreign corporation or partnership in all jurisdictions in which such qualification or authorization is required by law, except for jurisdictions in which the failure to so qualify or be authorized would not have a material adverse effect on the assets, properties, business, operations or condition (financial or otherwise) of ABIOMED and the Subsidiaries taken as a whole (the "Business of ABIOMED").

2.2. Capitalization.

(a) ABIOMED is authorized to issue 25,000,000 shares of Common Stock, of which 7,017,872 shares were issued and outstanding as of June 30, 1997, 2,346,000 shares of Class A Common Stock, $0.01 par value per share, none of which are issued and outstanding, 150,000 shares of Class A Preferred Stock, $0.01 par value per share, none of which are issued and outstanding and 1,000,000 shares of Class B Preferred Stock, $0.01 par value per share, none of which are issued and outstanding. No other class of capital stock of ABIOMED is authorized or outstanding. All of the issued and outstanding shares of ABIOMED's capital stock are duly authorized and are validly issued, fully paid, nonassessable and free of preemptive rights. None of the issued and outstanding shares have been issued in violation of any federal or state law except for violations that would not have a material adverse effect on the Business of ABIOMED.

(b) Options representing in the aggregate the right to purchase 969,785 shares of Common Stock pursuant to ABIOMED's 1992 Combination Stock Option Plan and ABIOMED's 1989 Non-Qualified Stock Option Plan for Non-Employee Directors are outstanding as of the date hereof.

(c) 90,718 shares of Common Stock are reserved for issuance under ABIOMED's 1988 Employee Stock Purchase Plan as of the date hereof.

(d) Except as set forth in paragraphs (a), (b) and (c) of this
Section 2.2, Section 2.2 of the Disclosure Schedule or as a result of the exercise of outstanding options or rights set forth therein, there are not, as of the date hereof, any other shares of ABIOMED capital stock authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements or commitments obligating ABIOMED to issue, transfer, sell, repurchase or redeem any shares of its capital stock or other securities of ABIOMED. To the best knowledge of ABIOMED, there are no written stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the voting of the capital stock of ABIOMED.

2.3. Issuance and Sale of Shares.

The issuance and sale of the Shares by ABIOMED has been duly authorized and the Shares have been duly reserved for issuance by all necessary corporate action on the part of ABIOMED, and the Shares, when issued and delivered against payment therefor, will be duly and validly issued, fully paid and non- assessable. Based in part on the representations made by the Investor set forth in Article 3 below, the offer, issuance and sale of the Shares pursuant to this Agreement are exempt from registration under the Securities Act of 1933, as amended (the


"Securities Act"), and applicable state securities laws. ABIOMED has complied with all applicable federal and state securities laws and with the Nasdaq By- Laws in connection with the offer, issuance and sale of the Shares.

2.4. Authority for Agreement.

The execution, delivery and performance by ABIOMED of this Agreement has been duly authorized by all necessary corporate action, and this Agreement has been duly executed and delivered by ABIOMED. This Agreement constitutes the valid and binding obligation of ABIOMED enforceable against ABIOMED in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

2.5. SEC Reports.

ABIOMED has previously delivered to the Investor its (a) Annual Report on Form 10-K for the year ended March 31, 1997 (the "ABIOMED 10-K"), as filed with the Securities and Exchange Commission (the "SEC'), (b) all proxy statements relating to ABIOMED's meetings of stockholders held or currently scheduled to be held since March 31, 1997 and (c) all other reports filed by ABIOMED with the SEC under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), since March 31, 1997. As of their respective dates, such reports complied in all material respects with applicable SEC requirements and did not contain any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading. ABIOMED has timely filed with the SEC all reports required to be flied under Section 13, 14 or 15(d) of the Exchange Act since March 31, 1997.

2.6. Financial Statements.

The financial statements contained in the ABIOMED 10-K have been prepared from, and are in accordance with, the books and records of ABIOMED and present fairly, in all material respects, the financial condition and results of operations of ABIOMED as of and for the periods presented therein, all in conformity with United States generally accepted accounting principles, consistently applied, except as otherwise noted therein.

2.7. Subsidiaries.

(a) The Disclosure Schedule sets forth all of the Subsidiaries and the jurisdiction in which each is incorporated or organized. Except as set forth on the Disclosure Schedule, all issued and outstanding shares or partnership interests of each Subsidiary are owned directly by ABIOMED free and clear of any charges, liens, encumbrances, security interests or adverse claims. As used in this Agreement, "Subsidiary" means any corporation, partnership or other legal entity of which ABIOMED or any Subsidiary owns, directly or indirectly, 50% or more of the stock or other equity interest entitled to vote for the election of directors.


(b) Except as set forth on the Disclosure Schedule, there are not as of the date hereof any other shares of capital stock or other equity interest of any Subsidiary authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements, claims or commitments of any nature whatsoever obligating any Subsidiary to issue, transfer, deliver, sell, repurchase or redeem any shares of the capital stock or other equity interest of any Subsidiary or obligating ABIOMED or any Subsidiary to grant, extend or enter into any such agreement. To the best knowledge of ABIOMED, there are no stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the capital stock of any Subsidiary.

(c) Except for the Subsidiaries, ABIOMED does not directly or indirectly own or have any investment in any of the capital stock of, and is not a party to a partnership or joint venture with, any other person.

2.8. Absence of Undisclosed ABIOMED Liabilities.

As of March 31, 1997, ABIOMED and the Subsidiaries had no material liabilities of any nature, whether accrued, absolute, contingent or otherwise,
(a) required to be reflected or disclosed on the balance sheets dated March 31, 1997 (or the notes thereto) included in the ABIOMED 10-K in the opinion of management that were not adequately reflected or reserved against on such balance sheets or (b) for the payment of any dividends, or any other distribution, to the stockholders of ABIOMED. ABIOMED and the Subsidiaries have no such liabilities, other than liabilities (i) which in the opinion of management as of March 31, 1987 are adequately reflected or reserved against on such balance sheet, (ii) incurred since March 31, 1997 in the ordinary course of business and consistent with past practice or (iii) that would not, in the aggregate, have a material adverse effect on the Business of ABIOMED.

2.9. No Material Adverse Change.

Since March 31, 1997, there has not been any material adverse change in the Business of ABIOMED.

2.10. Tax Matters.

(a) ABIOMED and each of the Subsidiaries have filed all tax reports and returns required to be filed by them and have paid or will timely pay all taxes and other charges shown as due on such reports and returns. Neither ABIOMED nor any of the Subsidiaries is delinquent in the payment of any material tax assessment or other governmental charge (including without limitation applicable withholding taxes). Any provision for taxes reflected in the financial statements referenced in Section 2.6 above is, to the best knowledge of ABIOMED, adequate for payment of any and all tax liabilities for periods ending on or before March 31, 1997 and there are no tax liens on any assets of ABIOMED or the Subsidiaries except liens for current taxes not yet due .

(b) Except as set forth in Section 2.10 of the Disclosure Schedule, there has not been any audit of any tax return filed by ABIOMED or any of the Subsidiaries and no audit


of any such tax return is in progress and neither ABIOMED nor any Subsidiary has been notified by any tax authority that any such audit is contemplated or pending. ABIOMED knows of no material tax deficiency or claim for additional taxes asserted or threatened to be asserted against ABIOMED or any of the Subsidiaries by any taxing authority and ABIOMED knows of no grounds for any such assessment. No extension of time with respect to any date on which a tax return was or is to be filed by ABIOMED or any of the Subsidiaries is in force, and no waiver or agreement by ABIOMED or any of the Subsidiaries is in force for the extension of time for the assessment or payment of any tax. For purposes of this Agreement, the term "tax" includes all federal, state, local and foreign taxes or assessments, including income, sales, gross receipts, excise, use, value added, royalty, franchise, payroll, withholding, property and import taxes and any interest or penalties applicable thereto.

2.11. No Breach.

The execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby will not: (a) violate any provision of the certificate of incorporation or by-laws of ABIOMED; (b) violate, conflict with or result in the breach of any of the terms or conditions of, result in modification of the effect of, or otherwise give any other contracting party the right to terminate, or constitute (or with notice or lapse of time or both constitute) a default under, any material instrument, contract or other agreement to which ABIOMED or any of the Subsidiaries is a party or to which any of the assets or properties of ABIOMED or any of the Subsidiaries may be bound or subject; (c) violate any order, judgment, injunction, award or decree of any court, arbitrator or governmental or regulatory body against, or binding upon, ABIOMED, any Subsidiary or upon any of their respective securities, properties, assets or businesses; (d) violate any statute, law or regulation of any jurisdiction as such statute, law or regulation relates to ABIOMED, any Subsidiary or any of their respective securities, properties, assets or businesses; (e) require the approval, consent or authorization of, or registration or filing with, any foreign, federal, state, local or other governmental or regulatory body or the approval, consent, waiver or notification of any stockholder, creditor, lessor or other person; or (f) result in the creation of any lien or other encumbrance on the assets or properties of ABIOMED or any of the Subsidiaries, excluding from clauses (b) - (f') such matters as would not in the aggregate have a material adverse effect on the Business of ABIOMED or upon the transactions contemplated hereby.

2.12. Actions and Proceedings.

There are no outstanding orders, judgments, injunctions, awards or decrees of any court, governmental or regulatory body or arbitration tribunal against ABIOMED, any Subsidiary or any of their respective properties or assets. There are no actions, suits or claims or legal, administrative or arbitral proceedings or, to the best knowledge of ABIOMED, investigations (whether or not the defense thereof or liabilities in respect thereof are covered by insurance) pending or, to the best knowledge of ABIOMED, threatened against ABIOMED, any Subsidiary or any of their respective properties or assets.


2.13. Compliance with Laws.

To its knowledge, neither ABIOMED nor any of the Subsidiaries is in violation of any statute, law, rule or regulation, or in default with respect to any judgment, writ, injunction, decree, rule or regulation of any court, governmental or regulatory body or arbitration tribunal, including without limitation laws relating to environmental protection, health and safety matters and labor and employment practices, except for such violations or defaults which do not, individually or in the aggregate, materially and adversely affect the Business of ABIOMED.

2.14. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of ABIOMED in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with ABIOMED or any action taken by ABIOMED, other than a fee payable by ABIOMED to UBS Securities LLC in connection with a fairness opinion being rendered by UBS Securities LLC.

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR

The Investor hereby represents and warrants to ABIOMED as follows:

3.1. Authority for Agreement.

The Investor has the power and authority to execute and deliver this Agreement and to perform all of his obligations hereunder. This Agreement has been duly executed and delivered by the Investor. This Agreement constitutes the valid and binding obligation of the Investor enforceable against the Investor in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

3.2. Investment.

The Investor is an accredited investor, as defined in Rule 501 of Regulation D under the Securities Act. The Investor is acquiring the Shares solely for his own account for investment purposes as a principal and not with a view to the public resale or distribution of all or any part thereof; provided however, that in making such representation, the Investor does not agree to hold the Shares for any minimum or specific term and reserves the right to sell, transfer or otherwise dispose of the Shares at any time in accordance with the terms of this Agreement and with federal and state securities laws applicable to such sale, transfer or disposition.

3.3. Restrictions on Transferability; Legend.

The Investor understands that the Shares have not been registered under the Securities Act or under the securities laws of any state or other jurisdiction in reliance upon exemptions thereunder. The Investor acknowledges and is aware that the Shares cannot be resold unless the


Shares are registered under the Securities Act and any applicable securities law of any state or other jurisdiction, or an exemption from registration is available. Each certificate representing the Shares shall bear a legend in substantially the following form (unless such Shares have been transferred pursuant to a registration statement under the Securities Act or, in the opinion of counsel acceptable to ABIOMED, such a legend is not required):

THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR ANY STATE SECURITIES LAW AND MAY NOT BE TRANSFERRED EXCEPT (i) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT OR (ii) UPON FIRST FURNISHING TO THE COMPANY AN OPINION OF COUNSEL SATISFACTORY TO IT THAT SUCH TRANSFER IS NOT IN VIOLATION OF THE REGISTRATION REQUIREMENTS OF THE ACT OR ANY STATE SECURITIES LAW.

3.4. Information.

The Investor has reviewed (a) the representations of ABIOMED contained in this Agreement and (b) the ABIOMED 10-K and has had the opportunity to make inquiry concerning ABIOMED and its business and personnel. The Investor is a director of ABIOMED and in such capacity is otherwise familiar with the business of ABIOMED. The officers of ABIOMED have made available to the Investor any and all written information that he has requested and have answered to the Investor's satisfaction all inquiries made by the Investor.

3.5. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of the Investor in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with the Investor, or any action taken by him.

ARTICLE 4. REGISTRATION RIGHTS

4.1. Certain Definitions. As used in this Article 4, the following terms shall have the following respective meanings:

(a) "Holders" shall mean the Investor and any of his successors and assigns (other than successors and assigns who acquire the Shares pursuant to a registered public offering or pursuant to a transaction covered by Rule 144 under the Securities Act) who hold Shares.

(b) "Registration Expenses" and "Selling Expenses" shall mean the expenses so described in Section 4.6.


(c) "Other Holders" shall mean all holders of the Company's securities other than Holders.

(d) "Shares" for purposes of this Article 4 shall have the meaning set forth in Section 1.1 hereof, with the exception that the term shall not include Shares which at any time have become salable pursuant to Rule 144(k) promulgated by the SEC pursuant to the Securities Act, or any similar successor rule.

(e) "Underwriter" shall mean each person who is or may be deemed an "underwriter," as that term is defined in Section 2(11) of the Securities Act, in respect of securities which shall have been registered by ABIOMED under the Securities Act pursuant to any of the provisions of this Article 4.

4.2. Required Registration.

If ABIOMED for itself or any of its security holders shall at any time or times after the first anniversary of the date hereof and prior to the seventh anniversary of the date hereof determine to register under the Securities Act any shares of Common Stock for an underwritten public offering other than (a) the registration of an offer and sale of securities to employees of, or other persons providing services to ABIOMED pursuant to an employee or similar benefit plan, registered on Form S-8 or comparable form; or (b) relating to a merger, acquisition or other transaction of the type described in Rule 145 under the Securities Act or comparable rule, registered on Form S-4 or similar form, ABIOMED will notify each Holder in each case of such determination at least ten
(10) days prior to the filing of such registration statement, and upon the request of a Holder given in writing within five days after the date of such notice, ABIOMED will use commercially reasonable efforts as soon as practicable thereafter to cause any of the Shares specified by such Holder to be included in such registration statement. Notwithstanding the foregoing, if the managing underwriter determines and advises in writing that the inclusion of all Shares of such requesting Holders and all shares of ABIOMED's Common Stock to be offered by ABIOMED and by Other Holders, whether covered by requests for registration or otherwise included, would interfere with the marketing of the securities to be sold by ABIOMED, or if the registration is at the request of a person or persons with a right to require registration, by that person or persons; then the number of shares of Common Stock otherwise to be included in the registration statement by Holders and Other Holders shall be reduced as follows: (i) there shall first be excluded shares proposed to be included by Other Holders not possessing legal rights to include the same pursuant to this section or any similar provision; and (ii) any further reduction shall be pro rata among such Holders and Other Holders (having such legal rights) in proportion to the number of shares as to which registration is requested by each; provided however, that there shall be no reduction in the number of shares to be included therein (x) by ABIOMED or (y) if the registration is at the request of a person or persons with a right to require such registration, by that person or persons. For purposes of making any such reduction, each holder (whether a Holder or Other Holder) which is a partnership, together with the affiliates, partners and retired partners of such holder, the estates and family members of any such partners and retired partners and of their spouses, and any trusts for the benefit of any of the foregoing persons shall be deemed to be a single holder and any pro rata reduction with respect to such holder shall


be based upon the aggregate amount of Shares sought to be sold by all entities and individuals so included in such holder, and the aggregate reduction so allocated to such holder shall be allocated among the entities and individuals included in such holder in such manner as such partnership may reasonably determine. If the managing underwriter determines and advises in writing that the inclusion in the registration statement of any shares of Common Stock to be sold by stockholders of ABIOMED would interfere with the marketing of the securities to be sold by ABIOMED, no notice need be given to any Holder pursuant to the first sentence of this section and no Holder will have the right to include its Shares in such registration statement.

4.3. Conditions of Obligations to Register Shares.

As conditions to ABIOMED's obligation hereunder to cause Shares to be included in a registration statement, the Holder shall provide such information and execute such documents as may reasonably be required in connection with such registration.

4.4. Registration Procedures.

If and whenever ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to include any of the Shares in a registration statement filed under the Securities Act, ABIOMED shall as expeditiously as possible:

(a) Prepare and file with the SEC a registration statement with respect to such Shares and use commercially reasonable efforts to cause such registration statement to become effective.

(b) Prepare and file with the SEC such amendments and supplements to such registration statement and the prospectus used in connection therewith as may be necessary to keep such registration statement effective until the Shares covered thereunder have been sold.

(c) Secure the designation and quotation of the Shares on Nasdaq or any national securities exchange on which the Common Stock is then listed. Furnish to each Holder such number of copies of the prospectus contained in such registration statement (including each preliminary prospectus), in conformity with the requirements of the Securities Act, and such other documents as such Holder may reasonably request in order to facilitate the disposition of the Shares owned by such Holder:

(e) Use commercially reasonable efforts to register or qualify the Shares covered by such registration statement under the securities or "blue sky" laws of such jurisdictions as each selling Holder shall reasonably request, and do any and all other acts and things which may be reasonably necessary or advisable to enable such Holder to consummate the disposition of the Shares owned by such Holder in such jurisdictions during the period specified in
Section 4.4(b), provided that ABIOMED shall not be required in connection herewith to execute a general consent to service of process in any jurisdiction.


(f) Notify each Holder immediately of any Shares covered by such registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus contained in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state any material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing, and as promptly as practicable, prepare, file and furnish to the Holder a reasonable number of copies of a supplement or an amendment to such prospectus as may be necessary so that such prospectus does not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing; provided however, that ABIOMED may delay preparing, filing and distributing any such supplement or amendment if ABIOMED determines in good faith that such supplement or amendment might, in the reasonable judgment of ABIOMED (i) interfere with or affect the negotiation or completion of a transaction that is being contemplated by ABIOMED (whether or not a final decision has been made to undertake such transaction) or (ii) involve initial or continuing disclosure obligations that are not in the best interests of ABIOMED's stockholders at such time; provided, further, that (x) ABIOMED will give notice (a "Standstill Notice") of any such delay no less than five (5) business days prior to such delay, (y) such delay shall not extend for a period of more than fifteen (15) business days without the written consent of the Holder and (z) ABIOMED may utilize such delay no more than once in each calendar year. Each Holder agrees, upon receipt of a Standstill Notice, forthwith to cease making offers and sales of the Shares pursuant to the registration statement or deliveries of the prospectus contained therein and to return to ABIOMED, for modification and exchange, the copies of such prospectus not theretofore delivered by such Holder; provided that ABIOMED shall forthwith prepare and deliver to such Holder after such delay a reasonable number of copies of any supplement to or amendment of such prospectus that may be necessary so that such prospectus does not include an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing.

(g) Use commercially reasonable efforts to prevent the issuance of any stop order or other order suspending the effectiveness of such registration statement and, if such an order is issued, to obtain the withdrawal at the earliest possible time and to notify the Holder of the issuance of such order and the resolution thereof.

(h) Furnish to the Holder and the Underwriter of the Holder's Shares, on the date that such registration statement becomes effective, (i) an opinion, dated such date, of outside counsel representing ABIOMED (and reasonably acceptable to the Holder) addressed to the Holder as to the effectiveness of the registration statement and its compliance as to form with the requirements of the Securities Act and such other matters as may be reasonably requested by the Holder (including, such additional matters as are customarily included in opinions delivered by company counsel in underwritten public offerings) and (ii) a letter, dated such date, from ABIOMED's independent certified public accountants, in form and substance as is customarily given by independent certified public accounts to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holder.


(i) Subject to the Holder entering into a confidentiality agreement reasonably acceptable to ABIOMED, provide the Holder and its representatives the opportunity to conduct a reasonable inquiry of ABIOMED's financial and other records during normal business hours and make available its officers, directors and employees for questions regarding information which the Holder may reasonably request in order to fulfill any due diligence obligation on its part.

(j) Permit counsel for the Holder to review such registration statement and all amendments and supplements thereto a reasonable period of time prior to the filing thereof with the SEC.

(k) Enter into and perform its obligations under an underwriting agreement, in usual and customary form reasonably acceptable to ABIOMED, with the underwriters of such offering. and to use its reasonable efforts to cause the conditions to the underwriters' performance thereunder to be met.

4.5. Description of Expenses.

All expenses incurred by ABIOMED in complying with any of the foregoing provisions of this Section 4, including without limitation all federal and state registration, qualification and filing fees, printing expenses, fees and disbursements of counsel to ABIOMED, and accountants' fees and expenses incident to or required by any such registration are herein called "Registration Expenses." All underwriting discounts and selling commissions applicable to the sale of Shares hereunder and the fees and disbursements of one counsel to the Holders with respect to any registration of the Shares hereunder are herein called "Selling Expenses." If ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to effect the registration of any of the Shares under the Securities Act, the Registration Expenses and Selling Expenses in connection with such registration shall be borne as follows:

(a) All Registration Expenses shall be borne by ABIOMED.

(b) Selling Expenses shall be borne pro rata among the Holders participating in the registration, except that each Holder shall bear the expenses of any separate counsel retained by it.

4.6. Indemnification.

In the event that ABIOMED registers under the Securities Act any Shares held by a Holder:

(a) ABIOMED agrees to indemnify and hold harmless such Holder, each person, if any, who controls such Holder within the meaning of the Securities Act, any Underwriter offering or selling the Holder's Shares and any person controlling such Underwriter, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under


which they were made, not misleading, unless such statement or omission was (i) made in reliance upon information furnished in writing by any such Holder, Underwriter or controlling person specifically for inclusion therein or (ii) contained in a preliminary prospectus and corrected in a final or amended prospectus if such Holder, Underwriter or controlling person received notice of such final or amended prospectus prior to the effective date of the registration statement but failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Shares to the person asserting such loss, claim, damage or liability, in any case where such delivery is required by the Securities Act.

(b) The obligations of ABIOMED under Section 4.2 with respect to any Holder are subject to the following conditions: (i) that each Holder whose Shares are to be included in any registration referred to in this Article 4 agrees, in writing, prior to the filing of such registration or filing, to indemnify and hold harmless ABIOMED and each person, if any, who controls ABIOMED within the meaning of the Securities Act, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein not misleading, but only with reference to statements or omissions made in reliance upon a statement in writing furnished by or on behalf of such Holder for inclusion therein; provided however, that the liability of each Holder to so indemnify shall be limited to the amount received by such Holder on the sale of his or her Shares pursuant to such registration statement, and (ii) that each such Holder enters into an underwriting agreement in usual and standard form (including a "lock-up" not exceeding 180 days of Shares not being sold in the underwritten offering) respecting such offering and uses its best reasonable efforts to cause the conditions to the Underwriters' performance thereunder to be met.

(c) Each Party entitled to indemnification under this Section 4.6 (the "Indemnified Party") shall give notice to the party required to provide indemnification (the "Indemnifying Party") promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom; provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld); and, provided, further, that the failure of any Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Section 4.6 unless and to the extent that such failure results in the forfeiture of substantive rights or' defenses by the Indemnifying Party. The Indemnified Party may participate in such defense at such party's expense; provided, however, that the Indemnifying Party shall pay such expense if, in the opinion of counsel to the Indemnified Party, representation of such Indemnified Party by the counsel retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between the Indemnified Party and any other party represented by such counsel. No Indemnifying Party, in the defense of any such claim or litigation shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement that does not include as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect of such claim or litigation and the Indemnifying Party shall


not be required to indemnify any Indemnified Party for any amount paid or payable by such Indemnified Party in settlement of any claim or litigation without such consent of the Indemnifying Party, which consent shall not be unreasonable withheld.


ARTICLE 5. MISCELLANEOUS

5.1. Assignment.

This Agreement may not be assigned or otherwise transferred by any Party without the consent of the other Party; provided, however, that (a) ABIOMED may, without such consent, assign its rights and obligations under this Agreement (i) in connection with a corporate reorganization, to any member of an affiliated group, all or substantially all of the equity interest of which is owned and controlled by ABIOMED or its direct or indirect parent corporation or (ii) in connection with a merger, consolidation or sale of substantially all of ABIOMED'S assets to an unrelated Third Party; provided however, that ABIOMED'S rights and obligations under this Agreement shall be assumed by its successor in interest in any such transaction and shall not be transferred separate from all or substantially all of its other business assets. Any purported assignment in violation of the preceding sentence shall be void. Any permitted assignee shall assume all obligations of its assignor under this Agreement in writing.

5.2. Severability.

Each Party hereby agrees that it does not intend to violate any public policy, statutory or common laws, rules, regulations, treaty or decision of any government agency or executive body thereof of any country or community or association of countries. Should one or more provisions of this Agreement be or become invalid, the Parties hereto shall substitute, by mutual consent, valid provisions for such invalid provisions, which valid provisions in their economic effect are sufficiently similar to the invalid provisions that it can be reasonably assumed that the Parties would have entered into this Agreement with such valid provisions. In case such valid provisions cannot be agreed upon, the invalidity of one or several provisions of this Agreement shall not affect the validity of this Agreement as a whole, unless the invalid provisions are of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without the invalid provisions.

5.3. Notices.

Any consent, notice or report required or permitted to be given or made under this Agreement by one of the Parties hereto to the other shall be in writing, delivered personally or by facsimile (and promptly confirmed by personal delivery or courier) or courier, postage prepaid (where applicable), addressed to such other Party at its address indicated below, or to such other address as the addressee shall have last furnished in writing to the address or in accordance with this Section 5.3, and shall be effective upon receipt by the addressee.


If to                         ABIOMED, Inc.
ABIOMED:                      33 Cherry Hill Drive
                              Danvers, Massachusetts 01923
                              Attention: President
                              Facsimile: (508) 777-8411

with a copy to:               Brown Rudnick Freed & Gesmer, P.C.
                              One Financial Center
                              Boston, Massachusetts 02111
                              Attention:  Philip J. Flink, Esquire
                              Facsimile: (617) 856-8201

If to                         John O'Brien
the Investor:                 Allmerica Financial
                              440 Lincoln Street
                              Worcester, MA  01653
                              Facsimile: (617) (508) 852-7588

                                   with a copy to:  <6>

5.4. Applicable Law.

This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts.

5.5. Entire Agreement.

This Agreement contains the entire understanding of the Parties with respect to the subject matter hereof. All express or implied agreements and understandings, either oral or written, heretofore made are expressly merged in and made a part of this Agreement. This Agreement may be amended, or any term hereof modified, only by a written instrument duly executed by the Parties. Each of the Parties hereby acknowledges that this Agreement is the result of mutual negotiation and therefore any ambiguity in their respective terms shall not be construed against the drafting Party.

5.6. Headings.

The captions to the several Articles and Sections hereof are not a part of this Agreement, but are merely guides or labels to assist in locating and reading the several Articles and Sections hereof.

5.7. Counterparts. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first set forth above.

ABIOMED, Inc.

By: ___________________________________

Title: ________________________________

/s/ John O'Brien
---------------------------------------
John O'Brien


COMMON STOCK PURCHASE AGREEMENT

between

ABIOMED, Inc.

and

Desmond H. O'Connell, Jr.

dated as of July 14, 1997


                               TABLE OF CONTENTS

ARTICLE 1. PURCHASE AND SALE OF SHARES.....................   1
 1.1. Authorization........................................   1
      -------------
 1.2. Purchase and Sale of the Shares......................   1
      -------------------------------
 1.3. Delivery of Certificates.............................   1
      ------------------------

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED.......   1
 2.1. Organization and Qualification.......................   2
      ------------------------------
 2.2. Capitalization.......................................   2
      --------------
 2.3. Issuance and Sale of Shares..........................   3
      ---------------------------
 2.4. Authority for Agreement..............................   3
      -----------------------
 2.5. SEC Reports..........................................   3
      -----------
 2.6. Financial Statements.................................   3
      --------------------
 2.7. Subsidiaries.........................................   4
      ------------
 2.8. Absence of Undisclosed ABIOMED Liabilities...........   4
      ------------------------------------------
 2.9. No Material Adverse Change...........................   4
      --------------------------
 2.10. Tax Matters.........................................   4
       -----------
 2.11. No Breach...........................................   5
       ---------
 2.12. Actions and Proceedings.............................   6
       -----------------------
 2.13. Compliance with Laws................................   6
       --------------------
 2.14. Brokerage...........................................   6
       ---------

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR..   6
 3.1. Authority for Agreement..............................   6
      -----------------------
 3.2. Investment...........................................   6
      ----------
 3.3. Restrictions on Transferability; Legend..............   7
      ---------------------------------------
 3.4. Information..........................................   7
      -----------
 3.5. Brokerage............................................   7
      ---------

ARTICLE 4. REGISTRATION RIGHTS.............................   7
 4.1. Certain Definitions..................................   8
      -------------------
 4.2. Required Registration................................   8
      ---------------------
 4.3. Conditions of Obligations to Register Shares.........   9
      --------------------------------------------
 4.4. Registration Procedures..............................   9
      -----------------------
 4.5. Description of Expenses..............................  11
      -----------------------
 4.6. Indemnification......................................  12
      ---------------

ARTICLE 5. MISCELLANEOUS...................................  14
 5.1. Assignment...........................................  14
      ----------
 5.2. Severability.........................................  14
      ------------
 5.3. Notices..............................................  14
      -------
 5.4. Applicable Law.......................................  15
      --------------
 5.5. Entire Agreement.....................................  15
      ----------------


5.6. Headings.............................................  15
     --------
5.7. Counterparts.........................................  15
     ------------


COMMON STOCK PURCHASE AGREEMENT

THIS COMMON STOCK PURCHASE AGREEMENT dated as of July 14, 1997 (the "Agreement") is between ABIOMED, Inc., a Delaware corporation having its principal place of business at 33 Cherry Hill Drive, Danvers, Massachusetts 01923 (ABIOMED"), and Desmond H. O'Connell, Jr. of <2> (the "Investor"). ABIOMED and the Investor are sometimes referred to herein individually as a "Party" and collectively as the "Parties."

In consideration of the mutual promises and of the covenants contained herein, the Parties hereby agree as follows:

ARTICLE 1. PURCHASE AND SALE OF SHARES

1.1. Authorization.

ABIOMED has duly authorized the issuance and sale to the Investor of Seven Thousand Six Hundred Ninety-Two (7,692) shares (the "Shares") of its Common Stock, $0.01 par value per share ("Common Stock").

1.2. Purchase and Sale of the Shares.

Concurrently with the execution and delivery of this Agreement, ABIOMED hereby issues and sells to the Investor, and the Investor hereby purchases from ABIOMED, the Shares at a purchase price of $13.00 per Share, for an aggregate purchase price of Ninety-Nine Thousand Nine Hundred Ninety-Six Dollars ($99,996.00). The purchase price shall be payable by the Investor to ABIOMED upon execution of this Agreement.

1.3. Delivery of Certificates.

On the date hereof, ABIOMED will deliver to the Investor one or more certificates representing the Shares registered in the name of the Investor against payment by the Investor of the purchase price by check or wire transfer.

ARTICLE 2. REPRESENTATIONS AND WARRANTIES OF ABIOMED

Except as otherwise set forth in the disclosure schedule delivered to the Investor on the date hereof (the "Disclosure Schedule"), the section numbers of which are numbered to correspond to the sections of this Agreement to which they refer, ABIOMED represents and warrants to the Investor as follows:

2.1. Organization and Qualification.

Each of ABIOMED and the Subsidiaries (as defined in Section 2.7) is a corporation or partnership duly organized, validly existing and in good standing under the laws of its state or jurisdiction of incorporation or formation with full power and authority to own, lease and operate its assets, properties and business and to carry on its business as now being and as heretofore conducted. Each of ABIOMED and the Subsidiaries is qualified or otherwise authorized to


transact business as a foreign corporation or partnership in all jurisdictions in which such qualification or authorization is required by law, except for jurisdictions in which the failure to so qualify or be authorized would not have a material adverse effect on the assets, properties, business, operations or condition (financial or otherwise) of ABIOMED and the Subsidiaries taken as a whole (the "Business of ABIOMED").

2.2. Capitalization.

(a) ABIOMED is authorized to issue 25,000,000 shares of Common Stock, of which 7,017,872 shares were issued and outstanding as of June 30, 1997, 2,346,000 shares of Class A Common Stock, $0.01 par value per share, none of which are issued and outstanding, 150,000 shares of Class A Preferred Stock, $0.01 par value per share, none of which are issued and outstanding and 1,000,000 shares of Class B Preferred Stock, $0.01 par value per share, none of which are issued and outstanding. No other class of capital stock of ABIOMED is authorized or outstanding. All of the issued and outstanding shares of ABIOMED's capital stock are duly authorized and are validly issued, fully paid, nonassessable and free of preemptive rights. None of the issued and outstanding shares have been issued in violation of any federal or state law except for violations that would not have a material adverse effect on the Business of ABIOMED.

(b) Options representing in the aggregate the right to purchase 969,785 shares of Common Stock pursuant to ABIOMED's 1992 Combination Stock Option Plan and ABIOMED's 1989 Non-Qualified Stock Option Plan for Non-Employee Directors are outstanding as of the date hereof.

(c) 90,718 shares of Common Stock are reserved for issuance under ABIOMED's 1988 Employee Stock Purchase Plan as of the date hereof.

(d) Except as set forth in paragraphs (a), (b) and (c) of this
Section 2.2, Section 2.2 of the Disclosure Schedule or as a result of the exercise of outstanding options or rights set forth therein, there are not, as of the date hereof, any other shares of ABIOMED capital stock authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements or commitments obligating ABIOMED to issue, transfer, sell, repurchase or redeem any shares of its capital stock or other securities of ABIOMED. To the best knowledge of ABIOMED, there are no written stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the voting of the capital stock of ABIOMED.

2.3. Issuance and Sale of Shares.

The issuance and sale of the Shares by ABIOMED has been duly authorized and the Shares have been duly reserved for issuance by all necessary corporate action on the part of ABIOMED, and the Shares, when issued and delivered against payment therefor, will be duly and validly issued, fully paid and non-assessable. Based in part on the representations made by the Investor set forth in Article 3 below, the offer, issuance and sale of the Shares pursuant to this Agreement are exempt from registration under the Securities Act of 1933, as amended (the


"Securities Act"), and applicable state securities laws. ABIOMED has complied with all applicable federal and state securities laws and with the Nasdaq By- Laws in connection with the offer, issuance and sale of the Shares.

2.4. Authority for Agreement.

The execution, delivery and performance by ABIOMED of this Agreement has been duly authorized by all necessary corporate action, and this Agreement has been duly executed and delivered by ABIOMED. This Agreement constitutes the valid and binding obligation of ABIOMED enforceable against ABIOMED in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

2.5. SEC Reports.

ABIOMED has previously delivered to the Investor its (a) Annual Report on Form 10-K for the year ended March 31, 1997 (the "ABIOMED 10-K"), as filed with the Securities and Exchange Commission (the "SEC'), (b) all proxy statements relating to ABIOMED's meetings of stockholders held or currently scheduled to be held since March 31, 1997 and (c) all other reports filed by ABIOMED with the SEC under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), since March 31, 1997. As of their respective dates, such reports complied in all material respects with applicable SEC requirements and did not contain any untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which they were made, not misleading. ABIOMED has timely filed with the SEC all reports required to be flied under Section 13, 14 or 15(d) of the Exchange Act since March 31, 1997.

2.6. Financial Statements.

The financial statements contained in the ABIOMED 10-K have been prepared from, and are in accordance with, the books and records of ABIOMED and present fairly, in all material respects, the financial condition and results of operations of ABIOMED as of and for the periods presented therein, all in conformity with United States generally accepted accounting principles, consistently applied, except as otherwise noted therein.

2.7. Subsidiaries.

(a) The Disclosure Schedule sets forth all of the Subsidiaries and the jurisdiction in which each is incorporated or organized. Except as set forth on the Disclosure Schedule, all issued and outstanding shares or partnership interests of each Subsidiary are owned directly by ABIOMED free and clear of any charges, liens, encumbrances, security interests or adverse claims. As used in this Agreement, "Subsidiary" means any corporation, partnership or other legal entity of which ABIOMED or any Subsidiary owns, directly or indirectly, 50% or more of the stock or other equity interest entitled to vote for the election of directors.


(b) Except as set forth on the Disclosure Schedule, there are not as of the date hereof any other shares of capital stock or other equity interest of any Subsidiary authorized or outstanding or any subscriptions, options, conversion or exchange rights, warrants, repurchase or redemption agreements, or other agreements, claims or commitments of any nature whatsoever obligating any Subsidiary to issue, transfer, deliver, sell, repurchase or redeem any shares of the capital stock or other equity interest of any Subsidiary or obligating ABIOMED or any Subsidiary to grant, extend or enter into any such agreement. To the best knowledge of ABIOMED, there are no stockholder agreements, voting trusts, proxies or other agreements, instruments or understandings with respect to the capital stock of any Subsidiary.

(c) Except for the Subsidiaries, ABIOMED does not directly or indirectly own or have any investment in any of the capital stock of, and is not a party to a partnership or joint venture with, any other person.

2.8. Absence of Undisclosed ABIOMED Liabilities.

As of March 31, 1997, ABIOMED and the Subsidiaries had no material liabilities of any nature, whether accrued, absolute, contingent or otherwise,
(a) required to be reflected or disclosed on the balance sheets dated March 31, 1997 (or the notes thereto) included in the ABIOMED 10-K in the opinion of management that were not adequately reflected or reserved against on such balance sheets or (b) for the payment of any dividends, or any other distribution, to the stockholders of ABIOMED. ABIOMED and the Subsidiaries have no such liabilities, other than liabilities (i) which in the opinion of management as of March 31, 1987 are adequately reflected or reserved against on such balance sheet, (ii) incurred since March 31, 1997 in the ordinary course of business and consistent with past practice or (iii) that would not, in the aggregate, have a material adverse effect on the Business of ABIOMED.

2.9. No Material Adverse Change.

Since March 31, 1997, there has not been any material adverse change in the Business of ABIOMED.

2.10. Tax Matters.

(a) ABIOMED and each of the Subsidiaries have filed all tax reports and returns required to be filed by them and have paid or will timely pay all taxes and other charges shown as due on such reports and returns. Neither ABIOMED nor any of the Subsidiaries is delinquent in the payment of any material tax assessment or other governmental charge (including without limitation applicable withholding taxes). Any provision for taxes reflected in the financial statements referenced in Section 2.6 above is, to the best knowledge of ABIOMED, adequate for payment of any and all tax liabilities for periods ending on or before March 31, 1997 and there are no tax liens on any assets of ABIOMED or the Subsidiaries except liens for current taxes not yet due.

(b) Except as set forth in Section 2.10 of the Disclosure Schedule, there has not been any audit of any tax return filed by ABIOMED or any of the Subsidiaries and no audit


of any such tax return is in progress and neither ABIOMED nor any Subsidiary has been notified by any tax authority that any such audit is contemplated or pending. ABIOMED knows of no material tax deficiency or claim for additional taxes asserted or threatened to be asserted against ABIOMED or any of the Subsidiaries by any taxing authority and ABIOMED knows of no grounds for any such assessment. No extension of time with respect to any date on which a tax return was or is to be filed by ABIOMED or any of the Subsidiaries is in force, and no waiver or agreement by ABIOMED or any of the Subsidiaries is in force for the extension of time for the assessment or payment of any tax. For purposes of this Agreement, the term "tax" includes all federal, state, local and foreign taxes or assessments, including income, sales, gross receipts, excise, use, value added, royalty, franchise, payroll, withholding, property and import taxes and any interest or penalties applicable thereto.

2.11. No Breach.

The execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby will not: (a) violate any provision of the certificate of incorporation or by-laws of ABIOMED; (b) violate, conflict with or result in the breach of any of the terms or conditions of, result in modification of the effect of, or otherwise give any other contracting party the right to terminate, or constitute (or with notice or lapse of time or both constitute) a default under, any material instrument, contract or other agreement to which ABIOMED or any of the Subsidiaries is a party or to which any of the assets or properties of ABIOMED or any of the Subsidiaries may be bound or subject; (c) violate any order, judgment, injunction, award or decree of any court, arbitrator or governmental or regulatory body against, or binding upon, ABIOMED, any Subsidiary or upon any of their respective securities, properties, assets or businesses; (d) violate any statute, law or regulation of any jurisdiction as such statute, law or regulation relates to ABIOMED, any Subsidiary or any of their respective securities, properties, assets or businesses; (e) require the approval, consent or authorization of, or registration or filing with, any foreign, federal, state, local or other governmental or regulatory body or the approval, consent, waiver or notification of any stockholder, creditor, lessor or other person; or (f) result in the creation of any lien or other encumbrance on the assets or properties of ABIOMED or any of the Subsidiaries, excluding from clauses (b) - (f') such matters as would not in the aggregate have a material adverse effect on the Business of ABIOMED or upon the transactions contemplated hereby.

2.12. Actions and Proceedings.

There are no outstanding orders, judgments, injunctions, awards or decrees of any court, governmental or regulatory body or arbitration tribunal against ABIOMED, any Subsidiary or any of their respective properties or assets. There are no actions, suits or claims or legal, administrative or arbitral proceedings or, to the best knowledge of ABIOMED, investigations (whether or not the defense thereof or liabilities in respect thereof are covered by insurance) pending or, to the best knowledge of ABIOMED, threatened against ABIOMED, any Subsidiary or any of their respective properties or assets.


2.13. Compliance with Laws.

To its knowledge, neither ABIOMED nor any of the Subsidiaries is in violation of any statute, law, rule or regulation, or in default with respect to any judgment, writ, injunction, decree, rule or regulation of any court, governmental or regulatory body or arbitration tribunal, including without limitation laws relating to environmental protection, health and safety matters and labor and employment practices, except for such violations or defaults which do not, individually or in the aggregate, materially and adversely affect the Business of ABIOMED.

2.14. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of ABIOMED in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with ABIOMED or any action taken by ABIOMED, other than a fee payable by ABIOMED to UBS Securities LLC in connection with a fairness opinion being rendered by UBS Securities LLC.

ARTICLE 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR

The Investor hereby represents and warrants to ABIOMED as follows:

3.1 Authority for Agreement.

The Investor has the power and authority to execute and deliver this Agreement and to perform all of his obligations hereunder. This Agreement has been duly executed and delivered by the Investor. This Agreement constitutes the valid and binding obligation of the Investor enforceable against the Investor in accordance with its terms, subject to applicable bankruptcy, insolvency, moratorium and similar laws affecting the rights and remedies of creditors generally and to general principles of equity.

3.2. Investment.

The Investor is an accredited investor, as defined in Rule 501 of Regulation D under the Securities Act. The Investor is acquiring the Shares solely for his own account for investment purposes as a principal and not with a view to the public resale or distribution of all or any part thereof; provided however, that in making such representation, the Investor does not agree to hold the Shares for any minimum or specific term and reserves the right to sell, transfer or otherwise dispose of the Shares at any time in accordance with the terms of this Agreement and with federal and state securities laws applicable to such sale, transfer or disposition.

3.3. Restrictions on Transferability; Legend.

The Investor understands that the Shares have not been registered under the Securities Act or under the securities laws of any state or other jurisdiction in reliance upon exemptions thereunder. The Investor acknowledges and is aware that the Shares cannot be resold unless the


Shares are registered under the Securities Act and any applicable securities law of any state or other jurisdiction, or an exemption from registration is available. Each certificate representing the Shares shall bear a legend in substantially the following form (unless such Shares have been transferred pursuant to a registration statement under the Securities Act or, in the opinion of counsel acceptable to ABIOMED, such a legend is not required):

THE SHARES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR ANY STATE SECURITIES LAW AND MAY NOT BE TRANSFERRED EXCEPT (i) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT OR (ii) UPON FIRST FURNISHING TO THE COMPANY AN OPINION OF COUNSEL SATISFACTORY TO IT THAT SUCH TRANSFER IS NOT IN VIOLATION OF THE REGISTRATION REQUIREMENTS OF THE ACT OR ANY STATE SECURITIES LAW.

3.3. Information.

The Investor has reviewed (a) the representations of ABIOMED contained in this Agreement and (b) the ABIOMED 10-K and has had the opportunity to make inquiry concerning ABIOMED and its business and personnel. The Investor is a director of ABIOMED and in such capacity is otherwise familiar with the business of ABIOMED. The officers of ABIOMED have made available to the Investor any and all written information that he has requested and have answered to the Investor's satisfaction all inquiries made by the Investor.

3.5. Brokerage.

No broker, finder, agent or similar intermediary has acted on behalf of the Investor in connection with this Agreement or the transactions contemplated hereby, and there are no brokerage commissions, finders fees or similar fees or commissions payable in connection therewith based on any agreement, arrangement or understanding with the Investor, or any action taken by him.

ARTICLE 4. REGISTRATION RIGHTS

4.1. Certain Definitions.

As used in this Article 4, the following terms shall have the following respective meanings:

(a) "Holders" shall mean the Investor and any of his successors and assigns (other than successors and assigns who acquire the Shares pursuant to a registered public offering or pursuant to a transaction covered by Rule 144 under the Securities Act) who hold Shares.

(b) "Registration Expenses" and "Selling Expenses" shall mean the expenses so described in Section 4.6.


(c) "Other Holders" shall mean all holders of the Company's securities other than Holders.

(d) "Shares" for purposes of this Article 4 shall have the meaning set forth in Section 1.1 hereof, with the exception that the term shall not include Shares which at any time have become salable pursuant to Rule 144(k) promulgated by the SEC pursuant to the Securities Act, or any similar successor rule.

(e) "Underwriter" shall mean each person who is or may be deemed an "underwriter," as that term is defined in Section 2(11) of the Securities Act, in respect of securities which shall have been registered by ABIOMED under the Securities Act pursuant to any of the provisions of this Article 4.

4.2. Required Registration.

If ABIOMED for itself or any of its security holders shall at any time or times after the first anniversary of the date hereof and prior to the seventh anniversary of the date hereof determine to register under the Securities Act any shares of Common Stock for an underwritten public offering other than (a) the registration of an offer and sale of securities to employees of, or other persons providing services to ABIOMED pursuant to an employee or similar benefit plan, registered on Form S-8 or comparable form; or (b) relating to a merger, acquisition or other transaction of the type described in Rule 145 under the Securities Act or comparable rule, registered on Form S-4 or similar form, ABIOMED will notify each Holder in each case of such determination at least ten
(10) days prior to the filing of such registration statement, and upon the request of a Holder given in writing within five days after the date of such notice, ABIOMED will use commercially reasonable efforts as soon as practicable thereafter to cause any of the Shares specified by such Holder to be included in such registration statement. Notwithstanding the foregoing, if the managing underwriter determines and advises in writing that the inclusion of all Shares of such requesting Holders and all shares of ABIOMED's Common Stock to be offered by ABIOMED and by Other Holders, whether covered by requests for registration or otherwise included, would interfere with the marketing of the securities to be sold by ABIOMED, or if the registration is at the request of a person or persons with a right to require registration, by that person or persons; then the number of shares of Common Stock otherwise to be included in the registration statement by Holders and Other Holders shall be reduced as follows: (i) there shall first be excluded shares proposed to be included by Other Holders not possessing legal rights to include the same pursuant to this section or any similar provision; and (ii) any further reduction shall be pro rata among such Holders and Other Holders (having such legal rights) in proportion to the number of shares as to which registration is requested by each; provided however, that there shall be no reduction in the number of shares to be included therein (x) by ABIOMED or (y) if the registration is at the request of a person or persons with a right to require such registration, by that person or persons. For purposes of making any such reduction, each holder (whether a Holder or Other Holder) which is a partnership, together with the affiliates, partners and retired partners of such holder, the estates and family members of any such partners and retired partners and of their spouses, and any trusts for the benefit of any of the foregoing persons shall be deemed to be a single holder and any pro rata reduction with respect to such holder shall


be based upon the aggregate amount of Shares sought to be sold by all entities and individuals so included in such holder, and the aggregate reduction so allocated to such holder shall be allocated among the entities and individuals included in such holder in such manner as such partnership may reasonably determine. If the managing underwriter determines and advises in writing that the inclusion in the registration statement of any shares of Common Stock to be sold by stockholders of ABIOMED would interfere with the marketing of the securities to be sold by ABIOMED, no notice need be given to any Holder pursuant to the first sentence of this section and no Holder will have the right to include its Shares in such registration statement.

4.3. Conditions of Obligations to Register Shares.

As conditions to ABIOMED's obligation hereunder to cause Shares to be included in a registration statement, the Holder shall provide such information and execute such documents as may reasonably be required in connection with such registration.

4.4. Registration Procedures.

If and whenever ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to include any of the Shares in a registration statement filed under the Securities Act, ABIOMED shall as expeditiously as possible:

(a) Prepare and file with the SEC a registration statement with respect to such Shares and use commercially reasonable efforts to cause such registration statement to become effective.

(b) Prepare and file with the SEC such amendments and supplements to such registration statement and the prospectus used in connection therewith as may be necessary to keep such registration statement effective until the Shares covered thereunder have been sold.

(c) Secure the designation and quotation of the Shares on Nasdaq or any national securities exchange on which the Common Stock is then listed.

(d) Furnish to each Holder such number of copies of the prospectus contained in such registration statement (including each preliminary prospectus), in conformity with the requirements of the Securities Act, and such other documents as such Holder may reasonably request in order to facilitate the disposition of the Shares owned by such Holder:

(e) Use commercially reasonable efforts to register or qualify the Shares covered by such registration statement under the securities or "blue sky" laws of such jurisdictions as each selling Holder shall reasonably request, and do any and all other acts and things which may be reasonably necessary or advisable to enable such Holder to consummate the disposition of the Shares owned by such Holder in such jurisdictions during the period specified in
Section 4.4(b), provided that ABIOMED shall not be required in connection herewith to execute a general consent to service of process in any jurisdiction.


(f) Notify each Holder immediately of any Shares covered by such registration statement at any time when a prospectus relating thereto is required to be delivered under the Securities Act of the happening of any event as a result of which the prospectus contained in such registration statement, as then in effect, includes an untrue statement of a material fact or omits to state any material fact required to be stated therein or necessary to make the statements therein not misleading in the light of the circumstances then existing, and as promptly as practicable, prepare, file and furnish to the Holder a reasonable number of copies of a supplement or an amendment to such prospectus as may be necessary so that such prospectus does not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing; provided however, that ABIOMED may delay preparing, filing and distributing any such supplement or amendment if ABIOMED determines in good faith that such supplement or amendment might, in the reasonable judgment of ABIOMED (i) interfere with or affect the negotiation or completion of a transaction that is being contemplated by ABIOMED (whether or not a final decision has been made to undertake such transaction) or (ii) involve initial or continuing disclosure obligations that are not in the best interests of ABIOMED's stockholders at such time; provided, further, that (x) ABIOMED will give notice (a "Standstill Notice") of any such delay no less than five (5) business days prior to such delay, (y) such delay shall not extend for a period of more than fifteen (15) business days without the written consent of the Holder and (z) ABIOMED may utilize such delay no more than once in each calendar year. Each Holder agrees, upon receipt of a Standstill Notice, forthwith to cease making offers and sales of the Shares pursuant to the registration statement or deliveries of the prospectus contained therein and to return to ABIOMED, for modification and exchange, the copies of such prospectus not theretofore delivered by such Holder; provided that ABIOMED shall forthwith prepare and deliver to such Holder after such delay a reasonable number of copies of any supplement to or amendment of such prospectus that may be necessary so that such prospectus does not include an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading in light of the circumstances then existing.

(g) Use commercially reasonable efforts to prevent the issuance of any stop order or other order suspending the effectiveness of such registration statement and, if such an order is issued, to obtain the withdrawal at the earliest possible time and to notify the Holder of the issuance of such order and the resolution thereof.

(h) Furnish to the Holder and the Underwriter of the Holder's Shares, on the date that such registration statement becomes effective, (i) an opinion, dated such date, of outside counsel representing ABIOMED (and reasonably acceptable to the Holder) addressed to the Holder as to the effectiveness of the registration statement and its compliance as to form with the requirements of the Securities Act and such other matters as may be reasonably requested by the Holder (including, such additional matters as are customarily included in opinions delivered by company counsel in underwritten public offerings) and (ii) a letter, dated such date, from ABIOMED's independent certified public accountants, in form and substance as is customarily given by independent certified public accounts to underwriters in an underwritten public offering, addressed to the underwriters, if any, and to the Holder.


(i) Subject to the Holder entering into a confidentiality agreement reasonably acceptable to ABIOMED, provide the Holder and its representatives the opportunity to conduct a reasonable inquiry of ABIOMED's financial and other records during normal business hours and make available its officers, directors and employees for questions regarding information which the Holder may reasonably request in order to fulfill any due diligence obligation on its part.

(j) Permit counsel for the Holder to review such registration statement and all amendments and supplements thereto a reasonable period of time prior to the filing thereof with the SEC.

(k) Enter into and perform its obligations under an underwriting agreement, in usual and customary form reasonably acceptable to ABIOMED, with the underwriters of such offering. and to use its reasonable efforts to cause the conditions to the underwriters' performance thereunder to be met.

4.5. Description of Expenses.

All expenses incurred by ABIOMED in complying with any of the foregoing provisions of this Section 4, including without limitation all federal and state registration, qualification and filing fees, printing expenses, fees and disbursements of counsel to ABIOMED, and accountants' fees and expenses incident to or required by any such registration are herein called "Registration Expenses." All underwriting discounts and selling commissions applicable to the sale of Shares hereunder and the fees and disbursements of one counsel to the Holders with respect to any registration of the Shares hereunder are herein called "Selling Expenses." If ABIOMED is required by the provisions of this Article 4 to use commercially reasonable efforts to effect the registration of any of the Shares under the Securities Act, the Registration Expenses and Selling Expenses in connection with such registration shall be borne as follows:

(a) All Registration Expenses shall be borne by ABIOMED.

(b) Selling Expenses shall be borne pro rata among the Holders participating in the registration, except that each Holder shall bear the expenses of any separate counsel retained by it.

4.6. Indemnification.

In the event that ABIOMED registers under the Securities Act any Shares held by a Holder:

(a) ABIOMED agrees to indemnify and hold harmless such Holder, each person, if any, who controls such Holder within the meaning of the Securities Act, any Underwriter offering or selling the Holder's Shares and any person controlling such Underwriter, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under


which they were made, not misleading, unless such statement or omission was (i) made in reliance upon information furnished in writing by any such Holder, Underwriter or controlling person specifically for inclusion therein or (ii) contained in a preliminary prospectus and corrected in a final or amended prospectus if such Holder, Underwriter or controlling person received notice of such final or amended prospectus prior to the effective date of the registration statement but failed to deliver a copy of the final or amended prospectus at or prior to the confirmation of the sale of the Shares to the person asserting such loss, claim, damage or liability, in any case where such delivery is required by the Securities Act.

(b) The obligations of ABIOMED under Section 4.2 with respect to any Holder are subject to the following conditions: (i) that each Holder whose Shares are to be included in any registration referred to in this Article 4 agrees, in writing, prior to the filing of such registration or filing, to indemnify and hold harmless ABIOMED and each person, if any, who controls ABIOMED within the meaning of the Securities Act, against any and all loss, liability or expense arising out of or based upon any untrue statement or alleged untrue statement of a material fact in any related registration statement, prospectus or preliminary prospectus or any omission or alleged omission of any material fact required to be stated therein or necessary to make the statements therein not misleading, but only with reference to statements or omissions made in reliance upon a statement in writing furnished by or on behalf of such Holder for inclusion therein; provided however, that the liability of each Holder to so indemnify shall be limited to the amount received by such Holder on the sale of his or her Shares pursuant to such registration statement, and (ii) that each such Holder enters into an underwriting agreement in usual and standard form (including a "lock-up" not exceeding 180 days of Shares not being sold in the underwritten offering) respecting such offering and uses its best reasonable efforts to cause the conditions to the Underwriters' performance thereunder to be met.

(c) Each Party entitled to indemnification under this Section 4.6 (the "Indemnified Party") shall give notice to the party required to provide indemnification (the "Indemnifying Party") promptly after such Indemnified Party has actual knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom; provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation, shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld); and, provided, further, that the failure of any Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Section 4.6 unless and to the extent that such failure results in the forfeiture of substantive rights or' defenses by the Indemnifying Party. The Indemnified Party may participate in such defense at such party's expense; provided, however, that the Indemnifying Party shall pay such expense if, in the opinion of counsel to the Indemnified Party, representation of such Indemnified Party by the counsel retained by the Indemnifying Party would be inappropriate due to actual or potential differing interests between the Indemnified Party and any other party represented by such counsel. No Indemnifying Party, in the defense of any such claim or litigation shall, except with the consent of each Indemnified Party, consent to entry of any judgment or enter into any settlement that does not include as an unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect of such claim or litigation and the Indemnifying Party shall


not be required to indemnify any Indemnified Party for any amount paid or payable by such Indemnified Party in settlement of any claim or litigation without such consent of the Indemnifying Party, which consent shall not be unreasonable withheld.


ARTICLE 5. MISCELLANEOUS

5.1. Assignment.

This Agreement may not be assigned or otherwise transferred by any Party without the consent of the other Party; provided, however, that (a) ABIOMED may, without such consent, assign its rights and obligations under this Agreement (i) in connection with a corporate reorganization, to any member of an affiliated group, all or substantially all of the equity interest of which is owned and controlled by ABIOMED or its direct or indirect parent corporation or (ii) in connection with a merger, consolidation or sale of substantially all of ABIOMED'S assets to an unrelated Third Party; provided however, that ABIOMED'S rights and obligations under this Agreement shall be assumed by its successor in interest in any such transaction and shall not be transferred separate from all or substantially all of its other business assets. Any purported assignment in violation of the preceding sentence shall be void. Any permitted assignee shall assume all obligations of its assignor under this Agreement in writing.

5.2. Severability.

Each Party hereby agrees that it does not intend to violate any public policy, statutory or common laws, rules, regulations, treaty or decision of any government agency or executive body thereof of any country or community or association of countries. Should one or more provisions of this Agreement be or become invalid, the Parties hereto shall substitute, by mutual consent, valid provisions for such invalid provisions, which valid provisions in their economic effect are sufficiently similar to the invalid provisions that it can be reasonably assumed that the Parties would have entered into this Agreement with such valid provisions. In case such valid provisions cannot be agreed upon, the invalidity of one or several provisions of this Agreement shall not affect the validity of this Agreement as a whole, unless the invalid provisions are of such essential importance to this Agreement that it is to be reasonably assumed that the Parties would not have entered into this Agreement without the invalid provisions.

5.3. Notices.

Any consent, notice or report required or permitted to be given or made under this Agreement by one of the Parties hereto to the other shall be in writing, delivered personally or by facsimile (and promptly confirmed by personal delivery or courier) or courier, postage prepaid (where applicable), addressed to such other Party at its address indicated below, or to such other address as the addressee shall have last furnished in writing to the address or in accordance with this Section 5.3, and shall be effective upon receipt by the addressee.


If to               ABIOMED, Inc.
ABIOMED:            33 Cherry Hill Drive
                    Danvers, Massachusetts 01923
                    Attention: President
                    Facsimile: (508) 777-84411

with a copy to:     Brown Rudnick Freed & Gesmer, P.C.
                    One Financial Center
                    Boston, Massachusetts 02111
                    Attention:  Philip J. Flink, Esquire
                    Facsimile: (617) 856-8201

If to               Desmond H. O'Connell, Jr.
the Investor:       Suite 24
                    2516 Highway 35
                    Manaquan, NJ  08736
                    Facsimile: (908) 223-4444

                         with a copy to:  <6>

5.4. Applicable Law.

This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Massachusetts.

5.5. Entire Agreement.

This Agreement contains the entire understanding of the Parties with respect to the subject matter hereof. All express or implied agreements and understandings, either oral or written, heretofore made are expressly merged in and made a part of this Agreement. This Agreement may be amended, or any term hereof modified, only by a written instrument duly executed by the Parties. Each of the Parties hereby acknowledges that this Agreement is the result of mutual negotiation and therefore any ambiguity in their respective terms shall not be construed against the drafting Party.

5.6. Headings.

The captions to the several Articles and Sections hereof are not a part of this Agreement, but are merely guides or labels to assist in locating and reading the several Articles and Sections hereof.

5.7 Counterparts.

This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.


IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first set forth above.

ABIOMED, Inc.

By:_________________________________

Title:______________________________

/s/ Desmond H. O'Connell, Jr.
------------------------------------

Desmond H. O'Connell, Jr.