UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

 

For the month of July, 2016

 

 

 

Commission File Number: 001-36582

 

Auris Medical Holding AG

(Exact name of registrant as specified in its charter)

 

Bahnhofstrasse 21

6300 Zug, Switzerland

(Address of principal executive office)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

 

Form 20-F

X

  Form 40-F

 

   

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

 

Yes   No

X

 

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):

 

Yes   No

 

 

 

 

 

On July 19, 2016 (the “Closing Date”), Auris Medical Holding AG (the “Company”) entered into a Loan and Security Agreement (the “Loan Agreement”) with several banks and other financial institutions or entities (collectively, the “Lender”) and Hercules Technology Growth Capital, Inc., a Maryland corporation, as administrative agent (“Hercules”).

 

The Loan Agreement provides the Company with a senior secured term loan facility (the “Loan Facility”) for up to $20,000,000. The initial $12,500,000 of the Loan Facility was drawn on July 19, 2016. An additional $7,500,000 is available to the Company at its option contingent on the satisfaction of milestones as set forth in the Loan Agreement.

 

The interest rate on amounts borrowed under the Loan Facility is calculated at the greater of either (a) 9.55%, or (b) the sum of (i) 9.55%, plus (ii) the prime rate minus 3.50%. The Loan Facility has a maturity date of January 2, 2020, with an interest-only period through July 1, 2017, and amortized payments of principal and interest thereafter.

 

The Company is required under the Loan Agreement to maintain a minimum cash balance of $5,000,000. The Company may prepay all, or a portion of, of the outstanding borrowed amounts by paying the entire principal balance and all accrued and unpaid interest thereon together with a Prepayment Charge (as defined below). If the borrowed amounts are prepaid on or prior to July 19, 2017, the prepayment charge will be 3.00% of the amount being prepaid. If the borrowed amounts are prepaid after July 19, 2017, but on or prior to July 19, 2018, the prepayment charge will be 2.00% of the amount being prepaid. Thereafter, the prepayment charge will be 1.00% of the amount being prepaid. Such prepayment charges are collectively referred to in this Report on Form 6-K as the “Prepayment Charges.”

 

In connection with the Loan Facility, the Company, pursuant to a Warrant Agreement, dated as of July 19, 2016, between the Company and Hercules (the “Warrant Agreement”), issued Hercules a warrant (the “Warrant”) to purchase common shares, with a nominal value of CHF 0.40 per share, of the Company (the “Common Shares”). As of the Closing Date, the Warrant is exercisable for 156,726 Common Shares with an exercise price of $3.94 per share. Upon Hercules making the second advance under the Loan Facility, the Warrant shall become exercisable for an additional 84,391 Common Shares with an exercise price of $3.94 per share.  The exercise price and the number of shares underlying the Warrant are subject to adjustment upon a merger event, reclassification of the Common Shares, subdivision or combination of the Common Shares and certain dividend payments. The Warrant is exercisable until the seventh anniversary of the Closing Date. The Company has agreed to use its commercially reasonable efforts to effect the registration under the Securities Act of 1933 of the Common Shares issued upon exercise of the Warrant by April 30, 2017.

 

The Loan Facility is secured by a pledge of 100% of the Company’s shares in Auris Medical AG, the Company’s principal operating subsidiary, all intercompany accounts receivables owed by Auris Medical AG and other Swiss subsidiaries of the Company to the Company and a security assignment of the Company’s bank accounts as specified in (i) the Share Pledge Agreement between the Company and Hercules, (the “Share Pledge Agreement”), (ii) the Claims Security Assignment Agreement between the Company and Hercules (the “Security Assignment Agreement”) and (iii) the Bank Account Claims Security Assignment Agreement between the Company and Hercules (the “Swiss Account Control Agreement”).

 

 

The Loan Agreement includes customary representations, warranties and restrictive covenants and sets out those events which would constitute an event of default thereunder (“Events of Default”). Under the terms of the Loan Agreement, upon and during the continuance of any one or more Events of Default, Hercules may, at its option and in addition to other remedies under the Loan Agreement, accelerate and demand payment of all or any part of the Company’s secured obligations together with a Prepayment Charge and declare them to be immediately due and payable.

 

The foregoing description of the Loan Agreement, the Warrant Agreement, the Share Pledge Agreement, the Security Assignment Agreement and the Swiss Account Control Agreement does not purport to be complete and is qualified in its entirety by reference to the Loan Agreement, the Warrant Agreement, the Share Pledge Agreement, the Security Assignment Agreement and the Swiss Account Control Agreement, copies of which are filed as Exhibits 10.1, 10.2, 10.3, 10.4 and 10.5 to this Report on Form 6-K, respectively, and are incorporated herein by reference.

 

On July 19, 2016, the Company issued a press release announcing the execution of the Loan Agreement. The Company is furnishing a copy of the press release, which is attached as Exhibit 99.1 to this Report on Form 6-K.

 

INCORPORATION BY REFERENCE

 

This Report on Form 6-K and exhibits 10.1, 10.2 and 10.3, 10.4 and 10.5 to this Report on Form 6-K shall be deemed to be incorporated by reference into the registration statements on Form F-3 (Registration Number 333-206710) and Form S-8 (Registration Numbers 333-198037 and 333-200805) of Auris Medical Holding AG and to be a part thereof from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished.

 

Exhibit 99.1 to this Report on Form 6-K shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act.

 

 

SIGNATURE

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

    Auris Medical Holding AG
     
     
      By: /s/ Thomas Meyer
        Name: Thomas Meyer
        Title: Chief Executive Officer

Date: July 19, 2016

 

 

EXHIBIT INDEX

 

Exhibit Number Description
10.1 Loan and Security Agreement, dated as of July 19, 2016, between Auris Medcial Holding AG, the several banks and other financial institutions or entities from time to time parties to the agreement and Hercules Capital, Inc.
10.2 Warrant Agreement, dated as of July 19, 2016, between Auris Medical Holding AG and Hercules Capital, Inc.
10.3 Share Pledge Agreement, dated July 19, 2016, between Auris Medical Holding AG and Hercules Capital, Inc.
10.4 Claims Security Assignment Agreement, dated July 19, 2016, between Auris Medical Holding AG and Hercules Capital, Inc.
10.5 Bank Account Claims Security Assignment Agreement, dated July 19, 2016, between Auris Medical Holding AG and Hercules Capital, Inc.
99.1 Press Release dated July 19, 2016

 

Exhibit 10.1

 

Execution Version

 

LOAN AND SECURITY AGREEMENT

 

THIS LOAN AND SECURITY AGREEMENT is made and dated as of July 19, 2016 and is entered into by and among (a) AURIS MEDICAL HOLDING AG, a company organized under the laws of Switzerland (“Borrower”), (b) the several banks and other financial institutions or entities from time to time parties to this Agreement (collectively, referred to as “Lender”), and (c) HERCULES CAPITAL, INC., a Maryland corporation, in its capacity as administrative agent for itself and the Lender (in such capacity, the “Agent”).

 

RECITALS

 

A.     Borrower has requested Lender to make available to Borrower up to two (2) term loans (each a “Term Loan Advance” and collectively, the “Term Loan Advances”) in an aggregate principal amount of up to Twenty Million Dollars ($20,000,000) (the “Maximum Term Loan Amount”); and

 

B.     Lender is willing to make the Term Loan Advances on the terms and conditions set forth in this Agreement.

 

AGREEMENT

 

NOW, THEREFORE, Borrower, Agent and Lender agree as follows:

 

SECTION 1. DEFINITIONS AND RULES OF CONSTRUCTION

 

1.1      Unless otherwise defined herein, the following capitalized terms shall have the following meanings:

 

“Account Control Agreement(s)” means (a) with respect to the bank accounts of the Borrower located in Switzerland, the Swiss Bank Account Control Agreement and (b) with respect to any U.S. Deposit Account, any agreement entered into by and among the Agent, Borrower and a third party Bank or other institution (including a Securities Intermediary) in which Borrower maintains a U.S. Deposit Account or an account holding Investment Property and which grants Agent a perfected first priority security interest in the subject account or accounts.

 

“Advance(s)” means a Term Loan Advance.

 

“Advance Date” means the funding date of any Advance.

 

“Advance Request” means a request for an Advance submitted by Borrower to Agent in substantially the form of Exhibit A, which account numbers shall be redacted for security purposes if and when filed publicly by Borrower.

 

“Affiliate” means (a) any Person that directly or indirectly controls, is controlled by, or is under common control with the Person in question, (b) any Person directly or indirectly owning, controlling or holding with power to vote ten percent (10%) or more of the outstanding voting

 

 

 

securities of another Person, (c) any Person ten percent (10%) or more of whose outstanding voting securities are directly or indirectly owned, controlled or held by another Person with power to vote such securities, or (d) any Person related by blood or marriage to any Person described in subsection (a), (b) or (c) of this paragraph. As used in the definition of “Affiliate,” the term “control” means the possession, directly or indirectly, of the power to direct or cause the direction of the management and policies of a Person, whether through ownership of voting securities, by contract or otherwise.

 

“Agent” has the meaning given to it in the preamble to this Agreement.

 

“Agreement” means this Loan and Security Agreement, as amended from time to time.

 

“AMAG” means Auris Medical AG, a company organized under the laws of Switzerland and a wholly-owned direct subsidiary of Borrower.

 

“Amortization Date” means July 1, 2017; provided , however , that if the Interest Only Period Extension Event occurs prior to July 1, 2017, the Amortization Date shall be April 1, 2018.

 

“Assignee” has the meaning given to it in Section 11.13.

 

“Board” means Borrower’s board of directors.

 

“Borrower” has the meaning given to it in the Recitals.

 

“Borrower Products” means all products, software, service offerings, technical data or technology that are currently being, and may be in the future, designed, manufactured or sold by Borrower or any Subsidiary or which Borrower or any Subsidiary intends to sell, license, or distribute in the future including any products or service offerings under development, collectively, together with all products, software, service offerings, technical data or technology that have been sold, licensed or distributed by Borrower or any Subsidiary since its incorporation.

 

“Business Day” means any day other than Saturday, Sunday and any other day on which banking institutions in the State of California are closed for business.

 

“Cash” means all cash, cash equivalents and liquid funds.

 

“Change in Control” means (i) any reorganization, recapitalization, consolidation or merger (or similar transaction or series of related transactions) of Borrower, sale or exchange of outstanding shares (or similar transaction or series of related transactions) of Borrower in which the holders of Borrower’s outstanding shares immediately before consummation of such transaction or series of related transactions do not, immediately after consummation of such transaction or series of related transactions, retain shares representing more than fifty percent (50%) of the voting power of the surviving entity of such transaction or series of related transactions (or the parent of such surviving entity if such surviving entity is wholly owned by such parent), in each case without regard to whether Borrower is the surviving entity or (ii) Borrower shall cease to 100% of the capital stock of AMAG.

 

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“Claims” has the meaning given to it in Section 11.10.

 

“Closing Date” means the date of this Agreement.

 

“Closing Date Term Commitment” means as to each Lender, the Closing Date Term Commitment specified for such Lender on Schedule 1.1.

 

“Collateral” has the meaning given to it in Section 3.2.

 

“Compliance Certificate” means a certificate in the form of Exhibit F.

 

“Confidential Information” has the meaning given to it in Section 11.12.

 

“Contingent Obligation” means, as applied to any Person, any direct or indirect liability, contingent or otherwise, of that Person with respect to (i) any Indebtedness, lease, dividend, letter of credit or other obligation of another, including any such obligation directly or indirectly guaranteed, endorsed, co-made or discounted or sold with recourse by that Person, or in respect of which that Person is otherwise directly or indirectly liable; (ii) any obligations with respect to undrawn letters of credit, corporate credit cards or merchant services issued for the account of that Person; and (iii) all obligations arising under any interest rate, currency or commodity swap agreement, interest rate cap agreement, interest rate collar agreement, or other agreement or arrangement designated to protect a Person against fluctuation in interest rates, currency exchange rates or commodity prices; provided, however, that the term “Contingent Obligation” shall not include endorsements for collection or deposit in the ordinary course of business. The amount of any Contingent Obligation shall be deemed to be an amount equal to the stated or determined amount of the primary obligation in respect of which such Contingent Obligation is made or, if not stated or determinable, the maximum reasonably anticipated liability in respect thereof as determined by such Person in good faith; provided, however, that such amount shall not in any event exceed the maximum amount of the obligations under the guarantee or other support arrangement.

 

“Copyright License” means any written agreement granting any right to use any Copyright or Copyright registration, now owned or hereafter acquired by Borrower or in which Borrower now holds or hereafter acquires any interest.

 

“Copyrights” means all copyrights, whether registered or unregistered, held pursuant to the laws of the United States, any State thereof, or of any other country.

 

“Deposit Accounts” means (a) with respect to any bank account located in the United States, a U.S. Deposit Account and (b) with respect to any bank account located outside of the United States, any bank account with the same functional characteristics of a U.S. Deposit Account. For the avoidance of doubt, the term “Deposit Accounts” includes each of Borrower’s accounts identified on Schedule 1 to the Swiss Account Control Agreement and any Future Bank Accounts (as defined in the Swiss Account Control Agreement) other than Excluded Accounts.

 

“Draw Period” means the period commencing upon the occurrence of the Term B Milestone Event and ending on the earlier to occur of (a) March 31, 2017, (b) the date which is

 

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forty-five (45) days after the consummation of the Term B Milestone Event, and (c) an Event of Default.

 

“Due Diligence Fee” means Forty Thousand Dollars ($40,000), which fee was paid to Lender prior to the Closing Date and is fully earned and non-refundable.

 

“End of Term Charge” shall have the meaning assigned to such term in Section 2.5.

 

“ERISA” means the Employee Retirement Income Security Act of 1974, as amended, and the regulations promulgated thereunder.

 

“Event of Default” has the meaning given to it in Section 9.

 

“Excluded Account” means a Deposit Account that is (a) a zero balance account, (b) a payroll, employee benefit, withholding tax or fiduciary account, (c) a cash collateral account established for the benefit of a letter of credit issuer with respect to letters of credit constituting Permitted Indebtedness provided that the aggregate monthly balances of all such Deposit Accounts under this clause (c) shall not at any time exceed $250,000 at any time outstanding or (d) a Deposit Account with a monthly balance not in excess of $100,000, provided that the aggregate monthly balances of all such Deposit Accounts under this clause (d) shall not at any time exceed $250,000 at any time outstanding.

 

“Facility Charge” means eighty-five one-hundredths of one percent (0.85%) of the Maximum Term Loan Amount, which is One Hundred Seventy Thousand Dollars ($170,000).

 

“Financial Statements” has the meaning given to it in Section 7.1.

 

“IFRS” are the International Financial Reporting Standards, a collection of guidelines and rules set by the International Accounting Standards Board (www.iasb.org) which are applicable to the circumstances as of the date of determination.

 

“Indebtedness” means indebtedness of any kind, including (a) all indebtedness for borrowed money or the deferred purchase price of property or services (excluding trade credit entered into in the ordinary course of business due within ninety (90) days), including reimbursement and other obligations with respect to surety bonds and letters of credit, (b) all obligations evidenced by notes, bonds, debentures or similar instruments, (c) all capital lease obligations, and (d) all Contingent Obligations.

 

“Insolvency Proceeding” is any proceeding by or against any Person under the United States Bankruptcy Code, any voluntary or involuntary liquidation, moratorium ( Nachlassstundung ), emergency moratorium ( Notstundung ) and composition with creditors ( Nachlassvertrag ) under Swiss law, or any other bankruptcy or insolvency law, including assignments for the benefit of creditors, compositions, extensions generally with its creditors, or proceedings seeking reorganization, arrangement, or other similar relief.

 

“Intellectual Property” means all of Borrower’s and its Subsidiaries’ Copyrights; Trademarks; Patents; Licenses; trade secrets and inventions; mask works; Borrower’s and its Subsidiaries’ applications therefor and reissues, extensions, or renewals thereof; and Borrower’s

 

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and its Subsidiaries’ goodwill associated with any of the foregoing, together with Borrower’s and its Subsidiaries’ rights to sue for past, present and future infringement of Intellectual Property and the goodwill associated therewith.

 

“Interest Only Period Extension Event” means the occurrence of both (i) the Term B Milestone Event and (ii) receipt by Borrower after the Closing Date but on or before July 1, 2017 of unrestricted and unencumbered net cash proceeds from an equity financing and/or corporate strategic transaction in an aggregate amount equal to or greater than Twenty Million Dollars ($20,000,000).

 

“Interest Rate Reduction Event” means (i) the occurrence of either (a) Borrower receives FDA approval for an NDA for AM-101 in patients with acute inner tinnitus or (b) Borrower receives EMA approval for an MAA for AM-101 in patients with acute inner tinnitus and (ii) receipt by Borrower after the Closing Date of unrestricted and unencumbered net cash proceeds from an equity financing and/or corporate strategic transaction in an aggregate amount equal to or greater than Twenty Million Dollars ($20,000,000).

 

“Investment” means any beneficial ownership (including stock, partnership or limited liability company interests) of or in any Person, or any loan, advance or capital contribution to any Person or the acquisition of all or a portion of the assets of another Person.

 

“Joinder Agreement” means for each Material U.S. Subsidiary, a completed and executed Joinder Agreement in substantially the form attached hereto as Exhibit G.

 

“Lender” has the meaning given to it in the preamble to this Agreement.

 

“License” means any Copyright License, Patent License, Trademark License or other license of rights or interests.

 

“Lien” means any mortgage, deed of trust, pledge, hypothecation, assignment for security, security interest, encumbrance, levy, lien or charge of any kind, whether voluntarily incurred or arising by operation of law or otherwise, against any property, any conditional sale or other title retention agreement, and any lease in the nature of a security interest.

 

“Loan” means the Advances made under this Agreement.

 

“Loan Documents” means this Agreement, the Notes (if any), the Account Control Agreements, the Joinder Agreements, all UCC Financing Statements, the Warrant, the Swiss Security Documents, any subordination agreement, and any other documents executed in connection with the Secured Obligations or the transactions contemplated hereby, as the same may from time to time be amended, modified, supplemented or restated. For the avoidance of doubt, the documents specified on Schedule 4.1 hereto constitute “Loan Documents.”

 

“Loan Party” means Borrower and each Subsidiary of Borrower that joins the Loan Documents as a borrower or guarantor thereunder (including any Material U. S. Subsidiary that has executed and delivered a Joinder Agreement) and which provides Collateral to secure the Secured Obligations.

 

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“Material Adverse Effect” means a material adverse effect upon: (i) the business, operations, properties, assets or financial condition of Borrower and its Subsidiaries taken as a whole; or (ii) the ability of Borrower to perform or pay the Secured Obligations in accordance with the terms of the Loan Documents, or the ability of Agent or Lender to enforce any of its rights or remedies with respect to the Secured Obligations; or (iii) the Collateral or Agent’s Liens on the Collateral or the priority of such Liens.

 

“Material U.S. Subsidiary” means a U.S. Subsidiary that (i) has assets equal to or in excess of 10% of the total assets of Borrower and its Subsidiaries or (ii) has revenues equal to or in excess of 10% of the total revenues of Borrower and its Subsidiaries.

 

“Maximum Term Loan Amount” shall have the meaning assigned to such term in the preamble to this Agreement.

 

“Maximum Rate” shall have the meaning assigned to such term in Section 2.2.

 

“Note(s)” means a promissory note or promissory notes to evidence Lender’s Loans substantially in the form of Exhibit B.

 

“ordinary course of business” and “ordinary course of Borrower’s business” means the normal and customary operations of Borrower and its Subsidiaries’ business and shall include, without limitation, collaboration or licensing transactions, or options to enter into collaboration or licensing transactions, that are customary in Borrower’s and its Subsidiaries’ industry.

 

“Patent License” means any written agreement granting any right with respect to any invention on which a Patent is in existence or a Patent application is pending, in which agreement Borrower or a Subsidiary of Borrower now holds or hereafter acquires any interest.

 

“Patents” means all letters patent of, or rights corresponding thereto, in the United States or in any other country, all registrations and recordings thereof, and all applications for letters patent of, or rights corresponding thereto, in the United States or any other country.

 

“Permitted Indebtedness” means: (i) Indebtedness of Borrower in favor of Lender or Agent arising under this Agreement or any other Loan Document; (ii) Indebtedness existing on the Closing Date which is disclosed in Schedule 1A; (iii) Indebtedness of up to One Million Dollars ($1,000,000) outstanding at any time secured by a Lien described in clause (vii) of the defined term “Permitted Liens,” provided such Indebtedness does not exceed the cost of the Equipment financed with such Indebtedness; (iv) Indebtedness to trade creditors incurred in the ordinary course of business, including Indebtedness incurred in the ordinary course of business with corporate credit cards; (v) Indebtedness that also constitutes a Permitted Investment; (vi) Subordinated Indebtedness; (vii) reimbursement obligations in connection with letters of credit that are secured by Cash and issued on behalf of Borrower or a Subsidiary thereof in an amount not to exceed One Million Dollars ($1,000,000) at any time outstanding, (viii) other Indebtedness in an amount not to exceed One Million Dollars ($1,000,000) at any time outstanding, (ix) intercompany Indebtedness owing by Borrower to one or more of its Subsidiaries so long as such indebtedness is expressly subordinated to repayment of the Secured Obligations in full pursuant to a subordination agreement or applicable law, (x) lease obligations for real property including obligations in connection with leasehold improvements in an amount not to exceed One Million

 

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Dollars ($1,000,000) at any time outstanding, (xi) Indebtedness consisting of any unsecured interest rate, currency or commodity swap agreement, interest rate cap agreement, interest rate collar agreement, or other agreement or arrangement designated to protect against fluctuation in interest rates, currency exchange rates or commodity prices, in each case, entered into in the ordinary course of business, (xii) Indebtedness arising from judgments, decrees or attachments the incurrence of which does not constitute an Event of Default hereunder, (xiii) obligations in respect of milestone payments under service agreements for clinical trials and (xiv) extensions, refinancings and renewals of any items of Permitted Indebtedness, provided that the principal amount is not increased or the terms modified to impose materially more burdensome terms upon Borrower or its Subsidiary, as the case may be.

 

“Permitted Investment” means: (i) Investments existing on the Closing Date which are disclosed in Schedule 1B; (ii) (a) marketable direct obligations issued or unconditionally guaranteed by the United States of America, Germany, Great Britain or Switzerland or any agency or any State thereof that are permitted by the Borrower’s board approved investment policy, (b) commercial paper maturing no more than one year from the date of creation thereof and currently having a rating of at least A-2 or P-2 from either Standard & Poor’s Corporation or Moody’s Investors Service, (c) certificates of deposit issued by any bank with assets of at least Five Hundred Million Dollars ($500,000,000) maturing no more than one year from the date of investment therein, and (d) money market accounts; (iii) repurchases of stock from former employees, directors, or consultants of Borrower under the terms of applicable repurchase agreements at the original issuance price of such securities in an aggregate amount not to exceed Two Hundred Fifty Thousand Dollars ($250,000) in any fiscal year, provided that no Event of Default has occurred, is continuing or would exist after giving effect to the repurchases; (iv) Investments accepted in connection with Permitted Transfers; (v) Investments (including debt obligations) received in connection with the bankruptcy or reorganization of customers or suppliers and in settlement of delinquent obligations of, and other disputes with, customers or suppliers arising in the ordinary course of Borrower’s business; (vi) Investments consisting of notes receivable of, or prepaid royalties and other credit extensions and advances, to customers and suppliers who are not Affiliates, in the ordinary course of business, provided that this subparagraph (vi) shall not apply to Investments of Borrower in any Subsidiary; (vii) Investments consisting of loans not involving the net transfer on a substantially contemporaneous basis of cash proceeds to employees, officers or directors relating to the purchase of capital stock of Borrower pursuant to employee stock purchase plans or other similar agreements approved by Borrower’s Board; (viii) Investments consisting of employee travel advances, employee relocation loans and other employee loans and advances in the ordinary course of business; (ix) Investments in Subsidiaries that are Loan Parties in the ordinary course of business, (x) Investments in Subsidiaries that are not Loan Parties in the ordinary course of business, provided that (A) all intercompany receivables owing by AMAG or any other Swiss Subsidiary of Borrower are subject to a Lien in favor of the Agent pursuant to the Swiss Security Documents, and (B) after giving effect to any such Investment, the aggregate amount of Cash of Borrower and its Subsidiaries that is held by Borrower’s Subsidiaries that are not Loan Parties shall not exceed the greater of (1) $2,000,000 and (2) 20% of the aggregate amount of Cash of Borrower and its Subsidiaries, (xi) joint ventures or strategic alliances in the ordinary course of Borrower’s business consisting of the licensing of technology (that would not result in a legal transfer of title of the licensed property), the development of technology or the providing of technical support, provided that any cash Investments by Borrower do not exceed One Million Dollars

 

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($1,000,000) in the aggregate in any fiscal year; (xii) advances to landlords for the construction of leasehold improvements made to premises occupied by Borrower; and (xiii) additional Investments that do not exceed One Million Dollars ($1,000,000) in the aggregate.

 

“Permitted Liens” means any and all of the following: (i) Liens in favor of Agent or Lender; (ii) Liens existing on the Closing Date which are disclosed in Schedule 1C; (iii) Liens for taxes, fees, assessments or other governmental charges or levies, either not delinquent or being contested in good faith by appropriate proceedings; provided, that Borrower maintains adequate reserves therefor in accordance with IFRS; (iv) Liens securing claims or demands of materialmen, artisans, mechanics, carriers, warehousemen, landlords and other like Persons arising in the ordinary course of Borrower’s business and imposed without action of such parties; provided, that the payment thereof is not yet required; (v) Liens arising from judgments, decrees or attachments in circumstances which do not constitute an Event of Default hereunder; (vi) the following deposits, to the extent made in the ordinary course of business: deposits under worker’s compensation, unemployment insurance, pension fund, social security, tax and other similar laws, or to secure the performance of bids, tenders or contracts (other than for the repayment of borrowed money) or to secure indemnity, performance or other similar bonds for the performance of bids, tenders or contracts (other than for the repayment of borrowed money) or to secure statutory obligations (other than Liens arising under ERISA (or other applicable pension laws) or environmental Liens) or surety or appeal bonds, or to secure indemnity, performance or other similar bonds; (vii) Liens on Equipment or software or other intellectual property constituting purchase money Liens and Liens in connection with capital leases securing Indebtedness permitted in clause (iii) of “Permitted Indebtedness”; (viii) Liens incurred in connection with Subordinated Indebtedness; (ix) leasehold interests in leases or subleases and licenses granted in the ordinary course of business and not interfering in any material respect with the business of the licensor; (x) Liens in favor of customs and revenue authorities arising as a matter of law to secure payment of custom duties that are promptly paid on or before the date they become due; (xi) Liens on insurance proceeds securing the payment of financed insurance premiums that are promptly paid on or before the date they become due (provided that such Liens extend only to such insurance proceeds and not to any other property or assets); (xii) customary contractual, statutory and common law rights of set-off and other similar rights as to deposits of cash and securities in favor of banks, other depository institutions and brokerage firms, in each case arising in the ordinary course of Borrower’s business with respect to cash management and operating account management; (xiii) easements, zoning restrictions, rights-of-way and similar encumbrances on real property imposed by law or arising in the ordinary course of business so long as they do not materially impair the value or marketability of the related property; (xiv) (A) Liens on Cash securing obligations permitted under clause (vii) of the definition of Permitted Indebtedness and (B) security deposits in connection with real property leases, the combination of (A) and (B) in an aggregate amount not to exceed One Million Dollars ($1,000,000) at any time; (xv) Liens incurred in connection with leasehold improvements made to the Borrower’s and its Subsidiaries’ facilities permitted under subsection (x) of Permitted Indebtedness; and (xvi) Liens incurred in connection with the extension, renewal or refinancing of the Indebtedness secured by Liens of the type described in clauses (i) through (xi) above and clauses (xiv) and (xv) above; provided, that any extension, renewal or replacement Lien shall be limited to the property encumbered by the existing Lien and the principal amount of the Indebtedness being extended, renewed or refinanced (as may have been reduced by any payment thereon) does not increase.

 

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“Permitted Transfers” means (i) sales of Inventory in the ordinary course of Borrower’s business, (ii) licenses, commercialization agreements, co-development agreements, and similar arrangements for the use of Intellectual Property in the ordinary course of Borrower’s business provided that such licenses or agreements shall be non-exclusive for the United States or any state thereof and could not result in a legal transfer of title of the licensed Intellectual Property or other property, or (iii) dispositions of worn-out, obsolete or surplus Equipment at fair market value in the ordinary course of business, (iv) Transfers constituting a Permitted Investment and (v) other arm’s length Transfers of assets having a fair market value of not more than Seven Hundred Fifty Thousand Dollars ($750,000) in the aggregate in any fiscal year.

 

“Person” means any individual, sole proprietorship, partnership, joint venture, trust, unincorporated organization, association, corporation, limited liability company, institution, other entity or government.

 

“Prepayment Charge” shall have the meaning assigned to such term in Section 2.5.

 

“Prime Rate” means the “prime rate” as reported in The Wall Street Journal, and if not reported, then the prime rate most recently reported in The Wall Street Journal.

 

“Receivables” means (i) all of Borrower’s Accounts, Instruments, Documents, Chattel Paper, Supporting Obligations, letters of credit, proceeds of any letter of credit, and Letter of Credit Rights, and (ii) all customer lists, software, and business records related thereto.

 

“Required Lenders” means at any time, the holders of more than fifty percent (50%) of the aggregate unpaid principal amount of the Term Loan Advances then outstanding.

 

“Second Tranche Term Commitment” means as to each Lender, the Second Tranche Term Commitment specified for such Lender on Schedule 1.1.

 

“Secured Obligations” means Borrower’s obligations under this Agreement and any Loan Document (other than the Warrant), including any obligation to pay any amount now owing or later arising (including, without limitation, the End of Term Charge and the Prepayment Charge).

 

“Securities Act” means the Securities Act of 1933, as amended.

 

“Subordinated Indebtedness” means Indebtedness subordinated to the Secured Obligations in amounts and on terms and conditions satisfactory to Agent in its sole discretion.

 

“Subsequent Financing” means the closing of any equity o ffering by Borrower after the Closing Date of its equity securities to one or more institutional investors for cash for financing purposes in a transaction or series of related transactions not registered under the Securities Act and results in aggregate proceeds to Borrower of at least $10,000,000.

 

“Subsidiary” means an entity, whether corporate, partnership, limited liability company, joint venture or otherwise, in which Borrower owns or controls fifty percent (50.0%) or more of the outstanding voting securities, including each entity listed on Schedule 1 hereto.

 

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“Swiss Collateral” means, collectively, the property described in the Swiss Security Documents in respect of which the Borrower has granted a security interest to the Agent pursuant to the terms thereof.

 

“Swiss Guidelines” means the following guidelines issued by the Swiss Federal Tax Administration (each as issued, amended or replaced from time to time):

 

(i)      guideline S-02.123 in relation to interbank loans of September 1986 ( Merkblatt Verrechnungssteuer auf Zinsen von Bankguthaben, deren Gläubiger Banken sind (Interbankguthaben) vom September 1986 );

 

(ii)      guideline S-02.130.1 in relation to money market instruments and book claims of April 1999 ( Merkblatt vom April 1999 betreffend Geldmarktpapiere und Buchforderungen inländischer Schuldner );

 

(iii)      guideline S-02.122.1 in relation to bonds of April 1999 ( Merkblatt Obligationen vom April 1999 );

 

(iv)      guideline S-02.128 in relation to syndicated credit facilities of January 2000 ( Merkblatt Steuerliche Behandlung von Konsortialdarlehen, Schuldscheindarlehen, Wechseln und Unterbeteiligungen vom Januar 2000 ); and

 

(v)      circular No. 34 of 26 July 2011 in relation to deposits ( Kreisschreiben Nr. 34 vom 26. Juli 2011 betreffend Kundenguthaben ).

 

“Swiss Non-Bank Rules” means, together, the Swiss Ten Non-Bank Rule and the Swiss Twenty Non-Bank Rule.

 

“Swiss Non-Qualifying Bank” means any Person which does not qualify as a Swiss Qualifying Bank.

 

“Swiss Qualifying Bank” means a financial institution acting on its own account which is licensed as a bank by the banking laws in force in its jurisdiction of incorporation or a branch of a financial institution, which is licensed as a bank by the banking laws in force in the jurisdiction where such branch is situated, and which, in each case, exercises as its main purpose a true banking activity, having bank personnel, premises, communication devices of its own and authority of decision making, all in accordance with the Swiss Guidelines.

 

“Swiss Security Documents” means collectively (i) the Share Pledge Agreement between Borrower and Agent regarding the shares of each Swiss Subsidiary of Borrower, (ii) the Security Assignment Agreement between Borrower and Agent regarding all intercompany accounts receivable owing by Auris Medical AG to Borrower and (iii) the Bank Account Claims Security Assignment Agreement (the “ Swiss Account Control Agreement ”) between Borrower and Agent, each dated as of the Closing Date, and as may be amended, modified or supplemented from time to time.

 

“Swiss Subsidiary” means any Subsidiary of Borrower that is organized under the laws of any jurisdiction within Switzerland.

 

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“Swiss Ten Non-Bank Rule” means the rule that the aggregate number of lenders under this Agreement and any Notes (including the Lenders and their permitted successors and assigns) which are Swiss Non-Qualifying Banks must not at any time exceed ten (10), all in accordance with the Swiss Guidelines.

 

“Swiss Twenty Non-Bank Rule” means the rule that the aggregate number of creditors (other than Swiss Qualifying Banks) of Borrower under all outstanding borrowings (including under the Loan Documents) made or deemed to be made by Borrower must not at any time exceed twenty (20), all in accordance with the Swiss Guidelines and it being understood that the Borrower shall at all times assume that five (5) of the Lenders are Swiss Non-Qualifying Banks.

 

“Term A Loan Advance” shall have the meaning assigned to such term in Section 2.1(a).

 

“Term B Loan Advance” shall have the meaning assigned to such term in Section 2.1(a).

 

“Term B Milestone Event” means confirmation by Agent and Lender in their sole discretion, that after the Closing Date, but on or prior to March 31, 2017, Borrower has completed a clinical study for TACTT2 that meets its co-primary endpoints with statistical significance and which will be the basis for a NDA submission by the Borrower to the FDA in 2017.

 

“Term Commitment” means as to any Lender, the obligation of such Lender, if any, to make a Term Loan Advance to Borrower in a principal amount not to exceed the amount set forth under the heading “Term Commitment” opposite such Lender’s name on Schedule 1.1.

 

“Term Loan Advance” and “Term Loan Advances” shall have the meaning assigned to such terms in Section 2.1(a).

 

“Term Loan Interest Rate” means for any day, a floating per annum rate equal to the greater of either (a) nine and fifty-five one-hundredths percent (9.55%), or (b) the sum of (i) nine and fifty-five one-hundredths percent (9.55%), plus (ii) the Prime Rate minus three and one-half percent (3.50%); provided , that , commencing on the 1 st calendar day of the calendar month following the month in which an Interest Rate Reduction Event occurs, “Term Loan Interest Rate” shall mean for any day, a floating per annum rate equal to the greater of either (a) nine and twenty one-hundredths percent (9.20%), or (b) the sum of (i) nine and twenty one-hundredths percent (9.20%), plus (ii) the Prime Rate minus three and one-half percent (3.50%).

 

“Term Loan Maturity Date” means January 2, 2020.

 

“Term Note” means a Promissory Note in substantially the form of Exhibit B.

 

“Trademark License” means any written agreement granting any right to use any Trademark or Trademark registration, now owned or hereafter acquired by Borrower or in which Borrower now holds or hereafter acquires any interest.

 

“Trademarks” means all trademarks (registered, common law or otherwise) and any applications in connection therewith, including registrations, recordings and applications in the

 

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United States Patent and Trademark Office or in any similar office or agency of the United States, any State thereof or any other country or any political subdivision thereof.

 

“Transfer” has the meaning specified in Section 7.8.

 

“UCC” means the Uniform Commercial Code as the same is, from time to time, in effect in the State of California; provided, that in the event that, by reason of mandatory provisions of law, any or all of the attachment, perfection or priority of, or remedies with respect to, Agent’s Lien on any Collateral is governed by the Uniform Commercial Code as the same is, from time to time, in effect in a jurisdiction other than the State of California, then the term “UCC” shall mean the Uniform Commercial Code as in effect, from time to time, in such other jurisdiction solely for purposes of the provisions thereof relating to such attachment, perfection, priority or remedies and for purposes of definitions related to such provisions.

 

“U.S. Collateral” has the meaning given to it in Section 3.2.

 

“U.S. Deposit Account” means a “deposit account,” as such term is defined in the UCC, and includes any checking account, savings account, or certificate of deposit.

 

“U.S. Subsidiary” means any Subsidiary of the Borrower that is organized under the laws of any jurisdiction within the United States of America.

 

“Warrant” means the Warrant Agreement dated as of even date hereof by and between Hercules Capital, Inc. and Borrower, as may be amended, restated or modified from time to time.

 

“Withholding Agent” means, as applicable, Borrower, any Lender and the Agent, as the context may require.

 

Unless otherwise specified, all references in this Agreement or any Annex or Schedule hereto to a “Section,” “subsection,” “Exhibit,” “Annex,” or “Schedule” shall refer to the corresponding Section, subsection, Exhibit, Annex, or Schedule in or to this Agreement. Unless otherwise specifically provided herein, any accounting term used in this Agreement or the other Loan Documents shall have the meaning customarily given such term in accordance with IFRS, and all financial computations hereunder shall be computed in accordance with IFRS, consistently applied. Unless otherwise defined herein or in the other Loan Documents, terms that are used herein or in the other Loan Documents and defined in the UCC shall have the meanings given to them in the UCC. All references to “Dollars” and “$” herein shall refer to United States Dollars.

 

SECTION 2. THE LOANs

 

2.1      Term Loan.

 

(a)     Advances. Subject to the terms and conditions of this Agreement, on the Closing Date, Lender will severally (and not jointly) make, in an amount not to exceed its respective Closing Date Term Commitment, and Borrower agrees to draw, one (1) Term Loan Advance in the aggregate amount of Twelve Million Five Hundred Thousand Dollars ($12,500,000) (the “Term A Loan Advance”). Subject to the terms and

 

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conditions of this Agreement, during the Draw Period, Lender will severally (and not jointly) make, in an amount not to exceed its respective Second Tranche Term Commitment, and Borrower may request, one (1) additional Term Loan Advance in an amount of Seven Million Five Hundred Thousand Dollars ($7,500,000) (the “Term B Loan Advance”). The Term A Loan Advance and the Term B Loan Advance are hereinafter referred to singly as the “Term Loan Advance” and collectively as the “Term Loan Advances.” The aggregate outstanding Term Loan Advances shall not exceed the Maximum Term Loan Amount. Proceeds of any Term Loan Advance shall be funded by the Lender into an account that is subject to a first priority perfected security interest in favor of Agent perfected by an Account Control Agreement.

 

(b)     Advance Request. To obtain the Term A Loan Advance on the Closing Date, Borrower shall complete, sign and deliver to Agent an Advance Request at least one (1) Business Day prior to the Closing Date. To obtain the Term B Loan Advance, Borrower shall complete, sign and deliver to Agent an Advance Request at least three (3) Business Days before the Advance Date. Lender shall fund the Term Loan Advance in the manner requested by the Advance Request provided that each of the conditions precedent to such Term Loan Advance is satisfied as of the requested Advance Date.

 

(c)     Interest. The principal balance of each Term Loan Advance shall bear interest thereon from such Advance Date at the Term Loan Interest Rate based on a year consisting of 360 days, with interest computed daily based on the actual number of days elapsed. The Term Loan Interest Rate will float and change on the day the Prime Rate changes from time to time.

 

(d)     Payment. Borrower will pay interest on each Term Loan Advance on the first (1 st ) Business Day of each month, beginning the month after the Advance Date.  Borrower shall repay the aggregate principal balance of the Term Loan Advances that are outstanding on the day immediately preceding the Amortization Date, in equal monthly installments of principal and interest (mortgage style) beginning on the Amortization Date and continuing on the first (1 st ) Business Day of each month thereafter until the Secured Obligations (other than inchoate indemnity obligations) are repaid. After any change in the Term Loan Interest Rate, Agent shall recalculate future payments of principal and interest to fully amortize the outstanding principal amount over the remaining scheduled monthly payments hereunder prior to the Term Loan Maturity Date in equal monthly installments of principal and interest (mortgage style). The entire principal balance of the Term Loan Advances and all accrued but unpaid interest hereunder, and all other Secured Obligations with respect to the Term Loan Advances, shall be due and payable on the Term Loan Maturity Date.  Borrower shall make all payments under this Agreement without setoff, recoupment or deduction and regardless of any counterclaim or defense. Once repaid, a Term Loan Advance or any portion thereof may not be reborrowed.

 

2.2      Maximum Interest. Notwithstanding any provision in this Agreement (including Section 2.3 below) or any other Loan Document, it is the parties’ intent not to contract for, charge or receive interest at a rate that is greater than the maximum rate permissible by law that an applicable court of competent jurisdiction shall deem applicable hereto (which if under the

 

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laws of the State of California shall be deemed to be the laws relating to permissible rates of interest on commercial loans) (the “Maximum Rate”). If a court of competent jurisdiction shall finally determine that Borrower has actually paid to Lender an amount of interest in excess of the amount that would have been payable if all of the Secured Obligations had at all times borne interest at the Maximum Rate, then such excess interest actually paid by Borrower shall be applied as follows: first, to the payment of the Secured Obligations consisting of the outstanding principal amount of the Term Loan Advances; second, after all principal is repaid, to the payment of Lender’s accrued interest, costs, expenses, professional fees and any other Secured Obligations; and third, after all Secured Obligations are repaid, the excess (if any) shall be refunded to Borrower.

 

2.3      Default Interest. In the event any payment is not paid on the scheduled payment date, an amount equal to five percent (5%) per annum of the past due amount shall be payable on demand. In addition, upon the occurrence and during the continuation of an Event of Default hereunder, all Secured Obligations, including principal, interest, compounded interest, and professional fees, shall bear interest at a rate per annum equal to the rate set forth in Section 2.1(c), plus five percent (5%) per annum. In the event any interest is not paid when due hereunder, delinquent interest shall be added to principal and shall bear interest on interest, compounded at the rate set forth in Section 2.1(c) or Section 2.3, as applicable.

 

2.4      Prepayment. At its option upon at least seven (7) Business Days prior notice to Agent, Borrower may prepay all or any portion, of the outstanding Advances by paying the entire principal balance (or portion thereof), all accrued and unpaid interest with respect to the principal balance being prepaid, together with a prepayment charge equal to the following percentage of the Advance amount being prepaid: if such Advance amounts are prepaid on or prior to July 19, 2017, three percent (3.0%); after July 19, 2017, but on or prior to July 19, 2018, two percent (2.0%); and thereafter, one percent (1.0%) (each, a “Prepayment Charge”). Borrower agrees that the Prepayment Charge is a reasonable calculation of Lender’s lost profits in view of the difficulties and impracticality of determining actual damages resulting from an early repayment of the Advances. Each prepayment pursuant to the foregoing shall be in a minimum amount of at least $2,500,000 and $100,000 increments in excess thereof. Upon the occurrence of a Change in Control, Borrower shall prepay the outstanding amount of all principal and accrued interest through the prepayment date and all unpaid Agent’s and Lender’s fees and expenses accrued to the date of the repayment (including the End of Term Charge) together with the applicable Prepayment Charge. Notwithstanding the foregoing, Agent and Lender agree to waive the Prepayment Charge if Agent and Lender agree in writing to refinance and re-document this Agreement prior to the Term Loan Maturity Date.

 

2.5      End of Term Charge. On the earliest to occur of (i) the Term Loan Maturity Date, (ii) the date that Borrower prepays the outstanding Secured Obligations (other than any inchoate indemnity obligations and any other obligations which, by their terms, are to survive the termination of this Agreement) in full, or (iii) the date that the Secured Obligations become due and payable, Borrower shall pay Lender a charge equal to five and seventy-five hundredths percent (5.75%) of the aggregate original principal amount of all Term Loan Advances extended by Lender to Borrower (the “End of Term Charge”). Notwithstanding the required payment date of such charge, it shall be deemed earned by Lender as of the Closing Date.

 

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2.6      Notes. If so requested by Lender by written notice to Borrower, then Borrower shall execute and deliver to Lender (and/or, if applicable and if so specified in such notice, to any Person who is an assignee of Lender pursuant to Section 11.13) (promptly after Borrower’s receipt of such notice) a Note or Notes to evidence Lender’s Loans.

 

2.7      Pro Rata Treatment. Each payment (including prepayment) on account of any fee and any Term Loan Advances shall be made pro rata according to the Term Commitments of the relevant Lender.

 

SECTION 3. SECURITY INTEREST

 

3.1      As security for the prompt and complete payment when due (whether on the payment dates or otherwise) of all the Secured Obligations, Borrower grants to Agent, pursuant to the Swiss Security Documents, a security interest in the Swiss Collateral.

 

3.2      As security for the prompt and complete payment when due (whether on the payment dates or otherwise) of all the Secured Obligations, each US Subsidiary that executes a Joinder Agreement grants to Agent a security interest in all of such Subsidiary’s right, title, and interest in and to the following personal property whether now owned or hereafter acquired (the “U.S. Collateral” and collectively with the Swiss Collateral, the “Collateral”): (a) Receivables; (b) Equipment; (c) Fixtures; (d) General Intangibles (other than Intellectual Property); (e) Inventory; (f) Investment Property; (g) Deposit Accounts; (h) Cash; (i) Goods; and all other tangible and intangible personal property of such Subsidiary whether now or hereafter owned or existing, leased, consigned by or to, or acquired by, such Subsidiary and wherever located, and any of such Subsidiary’s property in the possession or under the control of Agent; and, to the extent not otherwise included, all Proceeds of each of the foregoing and all accessions to, substitutions and replacements for, and rents, profits and products of each of the foregoing; provided, however, that the U.S. Collateral shall include all Accounts and General Intangibles that consist of rights to payment and proceeds from the sale, licensing or disposition of all or any part, or rights in, the Intellectual Property (the “Rights to Payment”). Notwithstanding the foregoing, if a judicial authority (including a U.S. or Swiss Bankruptcy Court) holds that a security interest in the underlying Intellectual Property is necessary to have a security interest in the Rights to Payment, then the U.S. Collateral shall automatically, and effective as of the date of this Agreement, include the Intellectual Property to the extent necessary to permit perfection of Agent’s security interest in the Rights to Payment. Notwithstanding the broad grant of security interest set forth in this Section 3.1, the U.S. Collateral shall not include rights held under a license that are not assignable by their terms without the consent of the licensor thereof (but only to the extent such restriction on assignment is enforceable under applicable law).

 

3.3      Notwithstanding any of the other provisions set forth in this Section 3, this Agreement shall not constitute a grant of a security interest in any Swiss Collateral and “U.S. Collateral” herein shall not include (A) any collateral to the extent Agent has a fully perfected Lien on all right, title and interest in such collateral pursuant to a Swiss Security Document, or (B) any property to the extent that such grant of a security interest is prohibited or not available under Swiss law, provided, however , that such security interest shall attach immediately at such time as such legal limitation is no longer effective or applicable.

 

SECTION 4. CONDITIONS PRECEDENT TO LOAN

 

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The obligation of Lender to make the Term Loan Advances hereunder is subject to the satisfaction by Borrower of the following conditions:

 

4.1      Initial Advance. On or prior to the Closing Date, Borrower shall have delivered to Agent, or caused to be delivered to Agent, the following:

 

(a)     executed copies (other than the Warrant, which shall be an original) of the Loan Documents specified on Schedule 4.1 hereto;

 

(b)     a legal opinion of Agent’s Swiss counsel;

 

(c)     a certificate dated the Closing Date and signed by the General Counsel of the Borrower attaching (i) a copy of resolutions of Borrower’s Board evidencing approval of (x) the Loan and other transactions evidenced by the Loan Documents; and (y) the Warrant and transactions evidenced thereby; (ii) copies of the Articles of Association ( Statuten ), as amended through the Closing Date, of Borrower and (iii) an excerpt from the commercial register and an excerpt from the debt collection register for Borrower from its state of incorporation; and

 

(d)     payment of the Due Diligence Fee, the Facility Charge and reimbursement of Agent’s and Lender’s current expenses reimbursable pursuant to this Agreement, which amounts (to the extent not otherwise paid) may be deducted from the initial Advance.

 

4.2      All Advances. On each Advance Date:

 

(a)     Agent shall have received (i) an Advance Request for the relevant Advance as required by Section 2.1(b), each duly executed by Borrower’s Chief Executive Officer, Chief Financial Officer or General Counsel, and (ii) any other documents Agent may reasonably request.

 

(b)     The representations and warranties set forth in this Agreement shall be true and correct in all material respects on and as of the Advance Date with the same effect as though made on and as of such date, except to the extent such representations and warranties expressly relate to an earlier date.

 

(c)     Borrower shall be in compliance with all the terms and provisions set forth herein and in each other Loan Document on its part to be observed or performed, and at the time of and immediately after such Advance no Event of Default shall have occurred and be continuing.

 

(d)     Each Advance Request shall be deemed to constitute a representation and warranty by Borrower (i) that the representations and warranties set forth in this Agreement are be true and correct in all material respects on and as of the Advance Date with the same effect as though made on and as of such date, except to the extent such representations and warranties expressly relate to an earlier date, (ii) that Borrower is in compliance with all the terms and provisions set forth in this Agreement and in each other Loan Document on its part to be observed or performed, (iii) that at the time of and

 

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immediately after such Advance no Event of Default shall have occurred and be continuing, and (iv) as to the other matters set forth in the Advance Request.

 

4.3      No Default. As of the Closing Date and each Advance Date, (i) no fact or condition exists that would (or would, with the passage of time, the giving of notice, or both) constitute an Event of Default and (ii) no event that has had or could reasonably be expected to have a Material Adverse Effect has occurred and is continuing.

 

SECTION 5. REPRESENTATIONS AND WARRANTIES OF BORROWER

 

Borrower represents and warrants that:

 

5.1      Corporate Status. Borrower is a corporation duly organized, legally existing and in good standing under the laws of Switzerland, and is duly qualified as a foreign corporation in all jurisdictions in which the nature of its business or location of its properties require such qualifications and where the failure to be qualified could reasonably be expected to have a Material Adverse Effect. Borrower’s present name, former names (if any), locations, place of formation, tax identification number, organizational identification number and other information are correctly set forth in Exhibit C, as may be updated by Borrower in a written notice (including any Compliance Certificate) provided to Agent after the Closing Date.

 

5.2      Collateral. Borrower owns the Swiss Collateral, free of all Liens, except for Permitted Liens. Each Subsidiary owns its assets (including Intellectual Property) free of all Liens, except for Permitted Liens. Borrower has the power and authority to grant to Agent a Lien in the Swiss Collateral as security for the Secured Obligations. Each Material U.S. Subsidiary that has signed a Joinder Agreement has the power and authority to grant to Agent a Lien in the U.S. Collateral as security for the Secured Obligations.

 

5.3      Consents. Borrower’s execution, delivery and performance of the Note(s) (if any), this Agreement and all other Loan Documents, and Borrower’s execution of the Warrant, (i) have been duly authorized by all necessary corporate action of Borrower, (ii) will not result in the creation or imposition of any Lien upon the Collateral, other than Permitted Liens and the Liens created by this Agreement and the other Loan Documents, (iii) do not violate any provisions of Borrower’s Articles of Association ( Statuten ), (iv) do not violate any material law, regulation, order, injunction, judgment, decree or writ to which Borrower or any of its Subsidiaries is subject and (v) do not violate any contract or agreement or require the consent or approval of any other Person which has not already been obtained, except in the case of clause (v) to the extent that such violation would not reasonably be expected to have a Material Adverse Effect. The individual or individuals executing the Loan Documents and the Warrant are duly authorized to do so.

 

5.4      Material Adverse Effect. Since March 31, 2016, no event that has had or could reasonably be expected to have a Material Adverse Effect has occurred and is continuing.

 

5.5      Actions Before Governmental Authorities. There are no actions, suits or proceedings at law or in equity or by or before any governmental authority now pending or, to the knowledge of Borrower, threatened against or affecting Borrower or any of its Subsidiaries or their respective property, that is reasonably expected to result in a Material Adverse Effect.

 

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5.6      Laws. Neither Borrower nor any of its Subsidiaries is in violation of any law, rule or regulation, or in default with respect to any judgment, writ, injunction or decree of any governmental authority, where such violation or default is reasonably expected to result in a Material Adverse Effect. Neither Borrower nor any of its Subsidiaries is in default in any manner under any provision of any agreement or instrument evidencing material Indebtedness, or any other material agreement to which it is a party or by which it is bound. Borrower and its Subsidiaries and, to the knowledge of Borrower and its Subsidiaries, their respective Affiliates and any agent or other party acting on behalf of Borrower, its Subsidiaries or its Affiliates, are in compliance with all applicable anti-money laundering, economic sanctions and anti-bribery laws and regulations, and none of the funds to be provided under this Agreement will be used, directly or indirectly, for any activities in violation of such laws and regulations.

 

5.7      Information Correct and Current. No information, report, Advance Request, financial statement, exhibit or schedule furnished, by or on behalf of Borrower or its Subsidiaries to Agent in connection with any Loan Document or included therein or delivered pursuant thereto contained, or, when taken as a whole, contains or will contain any material misstatement of fact or, when taken together with all other such information or documents, omitted, omits or will omit to state any material fact necessary to make the statements therein, in the light of the circumstances under which they were, are or will be made, not materially misleading at the time such statement was made or deemed made. Additionally, any and all financial or business projections provided by Borrower or its Subsidiaries to Agent, whether prior to or after the Closing Date, shall be (i) provided in good faith and based on the most current data and information available to Borrower and its Subsidiaries, and (ii) the most current of such projections provided to Borrower’s Board (it being understood that such projections are subject to significant uncertainties and contingencies, many of which are beyond the control of Borrower, that no assurance is given that any particular projections will be realized, that actual results may differ).

 

5.8      Tax Matters. Except as described on Schedule 5.8 and except those being contested in good faith with adequate reserves under IFRS, (a) Borrower and its Subsidiaries have filed all material federal, state and local tax returns that it is required to file, (b) Borrower and its Subsidiaries have duly paid or fully reserved for all taxes or installments thereof (including any interest or penalties) as and when due, which have or may become due pursuant to such returns, and (c) Borrower and its Subsidiaries have paid or fully reserved for any tax assessment received by Borrower or its Subsidiaries for the three (3) years preceding the Closing Date, if any (including any taxes being contested in good faith and by appropriate proceedings).

 

5.9      Intellectual Property Claims. AMAG is the sole beneficial owner of, or otherwise has the right to use, the Intellectual Property material to the business of Borrower and its Subsidiaries. Except as described on Schedule 5.9, to the knowledge of Borrower and its Subsidiaries, (i) each of the material Copyrights, Trademarks and Patents is valid and enforceable, (ii) no material part of the Intellectual Property has been judged invalid or unenforceable, in whole or in part, and (iii) no claim in writing has been made to Borrower or any Subsidiary that any material part of the Intellectual Property violates the rights of any third party. Exhibit D is a true, correct and complete list of each of the material Patents, material registered Trademarks, material registered Copyrights, and material agreements under which Borrower and/or its Subsidiaries license Intellectual Property from third parties (other than

 

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shrink-wrap software licenses), together with application or registration numbers, as applicable, owned by Borrower or any Subsidiary, in each case as of the Closing Date. Neither Borrower nor any Subsidiary is in material breach of, nor has Borrower or any Subsidiary failed to perform any material obligations under, any of the foregoing contracts, licenses or agreements and, to the knowledge of Borrower and its Subsidiaries, no third party to any such contract, license or agreement is in material breach thereof or has failed to perform any material obligations thereunder.

 

5.10      Intellectual Property. Except as described on Schedule 5.10, AMAG has all material rights with respect to Intellectual Property necessary or material in the operation or conduct of business of the Borrower and its Subsidiaries as currently conducted and proposed to be conducted by Borrower and its Subsidiaries. Without limiting the generality of the foregoing, and in the case of Licenses, except for restrictions that are unenforceable under Division 9 of the UCC, Borrower and/or its Subsidiaries the right, to the extent required to operate the business of Borrower and its Subsidiaries, to freely transfer, license or assign Intellectual Property necessary or material in the operation or conduct of the business of Borrower and its Subsidiaries as currently conducted and proposed to be conducted by Borrower and its Subsidiaries, without condition, restriction or payment of any kind (other than license payments in the ordinary course of business) to any third party, and Borrower and or its Subsidiaries own or have the right to use, pursuant to valid licenses, all software development tools, library functions, compilers and all other third-party software and other items that are material to the business of Borrower and its Subsidiaries and used in the design, development, promotion, sale, license, manufacture, import, export, use or distribution of Borrower Products except customary covenants in inbound license agreements and equipment leases where Borrower and/or its Subsidiary is the licensee or lessee.

 

5.11      Borrower Products. Except as described on Schedule 5.11, no Intellectual Property owned by Borrower or its Subsidiaries or Borrower Product has been or is subject to any actual or, to the knowledge of Borrower, threatened litigation, proceeding (including any proceeding in the United States Patent and Trademark Office or any corresponding foreign office or agency) or outstanding decree, order, judgment, settlement agreement or stipulation that restricts in any manner Borrower’s or its Subsidiaries’ use, transfer or licensing thereof or that may affect the validity, use or enforceability thereof. There is no decree, order, judgment, agreement, stipulation, arbitral award or other provision entered into in connection with any litigation or proceeding that obligates Borrower or any Subsidiary to grant licenses or ownership interest in any future Intellectual Property related to the operation or conduct of the business of Borrower and its Subsidiaries or Borrower Products. Neither Borrower nor any Subsidiary has received any written notice or claim, or, to the knowledge of Borrower and its Subsidiaries, oral notice or claim, challenging or questioning Borrower’s or any of its Subsidiaries’ ownership in any Intellectual Property (or written notice of any claim challenging or questioning the ownership in any licensed Intellectual Property of the owner thereof) or suggesting that any third party has any claim of legal or beneficial ownership with respect thereto nor, to Borrower’s and its Subsidiaries’ knowledge, is there a reasonable basis for any such claim. To Borrower’s and its Subsidiaries’ knowledge, neither Borrower’s or any Subsidiaries’ use of its Intellectual Property nor the production and sale of Borrower Products infringes the Intellectual Property or other rights of others.

 

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5.12      Financial Accounts. Exhibit E, as may be updated by Borrower from time to time after the Closing Date, pursuant to the Compliance Certificate submitted in connection with the delivery of the monthly financial statements pursuant to Section 7.1(c), is a true, correct and complete list of (a) all banks and other financial institutions at which Borrower or any Subsidiary maintains Deposit Accounts and (b) all institutions at which Borrower or any Subsidiary maintains an account holding Investment Property, and such exhibit correctly identifies the name, address and telephone number of each bank or other institution, the name in which the account is held, a description of the purpose of the account, and the complete account number therefor.

 

5.13      Employee Loans. Borrower has no outstanding loans to any employee, officer or director of Borrower or any of its Subsidiaries nor has Borrower guaranteed the payment of any loan made to an employee, officer or director of Borrower or any of its Subsidiaries by a third party.

 

5.14      Capitalization and Subsidiaries. Borrower’s capitalization as of the Closing Date is set forth on Schedule 5.14 annexed hereto. Borrower does not own any stock, partnership interest or other securities of any Person, except for Permitted Investments. Attached as Schedule 5.14, as may be updated by Borrower from time to time after the Closing Date, pursuant to the Compliance Certificate submitted in connection with the delivery of the quarterly financial statements pursuant to Section 7.1(b), is a true, correct and complete list of each Subsidiary.

 

5.15      Compliance with Swiss Twenty Non-Bank Rule. 5.16      Subject to compliance by Lender with Section 11.7, Borrower is in compliance with the Swiss Twenty Non-Bank Rule.

 

SECTION 6. INSURANCE; INDEMNIFICATION; Withholding

 

6.1      Coverage. Borrower shall cause AMAG and each other material Subsidiary to carry and maintain at all times commercial general liability insurance, on an occurrence form, against risks customarily insured against in the line of business of the Borrower and its Subsidiaries. Such risks shall include the risks of bodily injury, including death, property damage, personal injury and advertising injury.

 

6.2      Certificates. Borrower shall deliver to Agent certificates of insurance that evidence Borrower’s compliance with the insurance obligations in Section 6.1. Any failure of Agent to scrutinize such insurance certificates for compliance is not a waiver of any of Agent’s rights, all of which are reserved.

 

6.3      Indemnity. Borrower agrees to indemnify and hold Agent, Lender and their officers, directors, employees, agents, in-house attorneys, representatives and shareholders (each, an “Indemnified Person”) harmless from and against any and all claims, costs, expenses, damages and liabilities (including such claims, costs, expenses, damages and liabilities based on liability in tort, including strict liability in tort), including reasonable attorneys’ fees and disbursements and other costs of investigation or defense (including those incurred upon any appeal) (collectively, “Liabilities”), that may be instituted or asserted against or incurred by such Indemnified Person as the result of credit having been extended, suspended or terminated under

 

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this Agreement and the other Loan Documents or the administration of such credit, or in connection with or arising out of the transactions contemplated hereunder and thereunder, or any actions or failures to act in connection therewith, or arising out of the disposition or utilization of the Collateral, excluding in all cases Liabilities to the extent resulting solely from any Indemnified Person’s gross negligence or willful misconduct. Borrower agrees to pay, and to save Agent and Lender harmless from, any and all liabilities with respect to, or resulting from any delay in paying, any and all excise, sales or other similar taxes (excluding taxes imposed on or measured by the net income of Agent or Lender) that may be payable or determined to be payable with respect to any of the Collateral or this Agreement. In no event shall any Indemnified Person be liable on any theory of liability for any special, indirect, consequential or punitive damages (including any loss of profits, business or anticipated savings). This Section 6.3 shall survive the repayment of indebtedness under, and otherwise shall survive the expiration or other termination of, the Loan Agreement.

 

6.4      Withholding.

 

Without limiting the indemnity set forth in Section 6.3 above:

 

(a)     Any and all payments by or on account of any obligation of Borrower under any Loan Document shall be made without deduction or withholding for any taxes, and Borrower shall to comply with the requirements set forth in this Section 6.4. If any applicable law (as determined in the good faith discretion of an applicable Withholding Agent) requires the deduction or withholding of any tax from any such payment by a Withholding Agent, then the applicable Withholding Agent shall be entitled to make such deduction or withholding and shall timely pay the full amount deducted or withheld to the relevant governmental authority in accordance with applicable law and then the sum payable by Borrower shall be increased as necessary so that after such deduction or withholding has been made (including such deductions and withholdings applicable to additional sums payable under this Section 6.4) the applicable recipient receives an amount equal to the sum it would have received had no such deduction or withholding been made.

 

(b)     The interest rates provided for in the Loan Documents are minimum interest rates. The parties hereto have assumed, on the date of this Agreement, that Swiss withholding tax is not and will not become payable by Borrower on interest payments under this Agreement. Without prejudice to the foregoing clause (a), Borrower acknowledges and agrees that the interest rates set out in this Agreement are minimum interest rates which shall be adjusted in accordance with clauses (c) and (d) below if Swiss withholding tax becomes payable at any time on interest payments by Borrower under the Loan Documents.

 

(c)     If Swiss withholding tax applies on interest payments by Borrower under the Loan Documents, Borrower shall pay such additional amounts as shall be necessary in order for the net amounts received by Lender after withholding of Swiss withholding tax to be equal to the respective amounts of interest which would otherwise have been receivable in respect of the Loan Documents in the absence of the withholding of Swiss withholding tax.

 

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(d)     For the purpose of clauses (b) and (c) above, Swiss withholding tax shall be calculated, deducted and paid by Borrower to the Swiss Federal Tax Administration on the amount of interest so recalculated at a rate of thirty-five percent (35.0%) (or such other rate as applicable from time to time), unless a tax ruling obtained from the Swiss Federal Tax Administration confirms that such rate is, pursuant to any double-taxation treaty, a specified lesser rate in relation to specified Lenders in which case such lesser rate shall be applied in relation to the relevant Lender.

 

(e)     To the extent that interest payable under a Loan Document becomes subject to Swiss withholding tax, each relevant Lender and Borrower shall promptly co-operate in completing any procedural formalities (including submitting forms and documents required by the appropriate Tax authority) to the extent possible and necessary (a) to make interest payments without them being subject to Swiss withholding tax or (b) to being subject to Swiss withholding tax at a rate reduced under applicable double taxation treaties or (c) for a Lender to obtain a full or partial refund of Swiss withholding tax under applicable double taxation treaties.

 

6.5      Compliance with Swiss Twenty Non-Bank Rule (a)      . Subject to compliance by the Lenders with Section 11.7, Borrower shall be at all times during the term of this Agreement in compliance with the Swiss Twenty Non-Bank Rule.

 

6.6      Confirmation of Lender’s Status . Lender confirms that it is a single (1) person only for the purpose of the Swiss Non-Bank Rules and any other Person that shall become a Lender pursuant to Section 11.7(a) of this Agreement shall be deemed to have confirmed that it is a Swiss Qualifying Bank or, if not, a single (1) person only for the purpose of Swiss Non-Bank Rules. The Borrower may request a Lender to confirm (i) whether or not it a Swiss Qualifying Bank or (ii) whether it does count as a single (1) person for purposes of the Swiss Non-Bank Rules, if it reasonably believes that that Lender’s status has changed during the term of this Agreement.

 

SECTION 7. COVENANTS OF BORROWER

 

Borrower agrees as follows:

 

7.1      Financial Reports. Borrower shall furnish to Agent the financial statements and reports listed hereinafter (the “Financial Statements”):

 

(a)     as soon as practicable (and in any event within thirty (30) days) after the end of each month commencing with the month ending July 31, 2016, unaudited interim and year to date financial statements as of the end of such month (prepared on a consolidated and consolidating basis, if applicable), including balance sheet and related statements of income and cash-flows accompanied by a report detailing any material contingencies (including the commencement of any material litigation by or against Borrower) or any other occurrence that would reasonably be expected to have a Material Adverse Effect, certified by Borrower’s Chief Executive Officer, Chief Financial Officer or Vice President of Finance to the effect that they have been prepared in accordance with IFRS, except (i) for the absence of footnotes, (ii) that they are subject to normal

 

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year-end adjustments, and (iii) they do not contain certain non-cash items that are customarily included in quarterly and annual financial statements;

 

(b)     as soon as practicable (and in any event within sixty (60) days) after the end of each of the first three fiscal quarters of each fiscal year of Borrower, commencing with the fiscal quarter ending September 30, 2016, unaudited interim and year-to-date financial statements as of the end of such fiscal quarter (prepared on a consolidated and consolidating basis, if applicable), including balance sheet and related statements of income and cash flows accompanied by a report detailing any material contingencies (including the commencement of any material litigation by or against Borrower) or any other occurrence that would reasonably be expected to have a Material Adverse Effect, certified by Borrower’s Chief Executive Officer, Chief Financial Officer or Vice President of Finance to the effect that they have been prepared in accordance with IFRS, except (i) for the absence of footnotes, and (ii) that they are subject to normal year-end adjustments;

 

(c)     as soon as practicable (and in any event within (120) days) after the end of each fiscal year of Borrower commencing with the fiscal year ending December 31, 2016, audited financial statements as of the end of such year (prepared on a consolidated and consolidating basis, if applicable), including balance sheet and related statements of income and cash flows, and setting forth in comparative form the corresponding figures for the preceding fiscal year, which financial statements shall be unqualified (except for any qualification arising from the Term Loan Advances maturing, in accordance with their terms on a non-accelerated basis, less than one year following the date of such financial statements) and certified by a firm of independent certified public accountants selected by Borrower and reasonably acceptable to Agent (it being understood that Borrower’s independent certified public accountants on the Closing Date are acceptable to Agent) and accompanied by any management report from such accountants;

 

(d)     as soon as practicable (and in any event within thirty (30) days) after the end of each month, commencing with the month ending August 31, 2016 and as soon as practicable (and in any event within forty-five (45) days) the end of each fiscal quarter, commencing with the fiscal quarter ending September 30, 2016, a Compliance Certificate in the form of Exhibit F;

 

(e)     promptly after the sending or filing thereof, as the case may be, copies of any material proxy statements, financial statements or reports that Borrower has made available to holders of its capital stock and copies of any material regular, periodic and special reports (Form 6-K) or registration statements that Borrower files with the Securities and Exchange Commission or any governmental authority that may be substituted therefor, or any national securities exchange, provided that any such document or report that Borrower files with the Securities and Exchange Commission via the Securities and Exchange Commission’s EDGAR system shall be deemed to be furnished to Agent at the time an e-mail link to such documents filed via the EDGAR system is delivered by Borrower to Agent; Borrower shall also notify Agent in the Compliance Certificate delivered in connection with the submission of quarterly financial statements pursuant to Section 7.1(b) of any legal process served on the Borrower or any

 

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of its Subsidiaries during the fiscal quarter in respect of which financial statements are delivered, affecting the Borrower, its Subsidiaries, any their respective properties or assets or the Liens of the Agent under the Loan Documents, which legal process is reasonably likely to result in damages, expenses or liabilities in excess of Two Hundred Fifty Thousand Dollars ($250,000); and

 

(f)     annual budget covering Borrower and its Subsidiaries promptly following its approval by Borrower’s Board, and in any event, within thirty (30) days prior to the end of Borrower’s fiscal year, and any material changes thereto or to the corporate organizational structure of Borrower and its Subsidiaries or any clinical study, and other business or financial information reasonably requested by Agent.

 

Borrower shall not make any material change in its (a) accounting policies or reporting practices, except as required by IFRS or (b) fiscal years or fiscal quarters, in each case, without the prior written approval of the Agent, which shall not be unreasonably withheld, delayed or conditioned. The fiscal year of Borrower shall end on December 31.

 

The executed Compliance Certificate may be sent via email to Agent at legal@herculestech.com. All Financial Statements required to be delivered pursuant to clauses (a), (b) and (c) shall be sent via e-mail to financialstatements@herculestech.com with a copy to legal@herculestech.com provided, that if e-mail is not available or sending such Financial Statements via e-mail is not possible, they shall be sent via facsimile to Agent at: (866) 468-8916, attention Chief Credit Officer, provided that notwithstanding the foregoing, any Financial Statement or report that Borrower files with the Securities and Exchange Commission via the Securities and Exchange Commission’s EDGAR system shall be deemed to be furnished to Agent at the time an e-mail link to such documents filed via the EDGAR system is delivered by Borrower to Agent.

 

Notwithstanding the foregoing, documents required to be delivered pursuant to the terms hereof (to the extent any such documents are included in materials otherwise filed with the SEC) may be delivered electronically and if so delivered, shall be deemed to have been delivered on the date on which Borrower e-mails a link thereto to Agent; provided that Borrower shall directly provide Agent by e-mail all Financial Statements required to be delivered pursuant to Section 7.1(a) hereunder.

 

7.2      Inspection Rights. Borrower shall permit any representative that Agent or Lender authorizes, including its attorneys and accountants, to inspect the Collateral and examine and make copies and abstracts of the books of account and records of Borrower at reasonable times and upon reasonable advance notice during normal business hours; provided, however, that so long as no Event of Default has occurred and is continuing, such examinations shall be limited to no more often than twice per fiscal year. In addition, any such representative shall have the right to meet with management and officers of Borrower to discuss such books of account and records. In addition, Agent or Lender shall be entitled at reasonable times and intervals to consult with and advise the management and officers of Borrower concerning significant business issues affecting Borrower. Such consultations shall not unreasonably interfere with Borrower’s business operations. Notwithstanding the foregoing, Borrower shall not be required to disclose any information Agent or Lender to the extent that Borrower has determined in good

 

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faith that (x) it is prohibited from furnishing such other information by applicable law or a contractual obligation (it being understood and agreed that this ‎Section 7.2 shall not be applied to augment the periodic reporting obligations of Borrower under this Agreement), (y) constitutes non-financial trade secrets or non-financial proprietary information or (z) such information is subject to attorney-client or similar privilege or constitutes attorney work product.

 

The parties intend that the rights granted Agent and Lender shall constitute “management rights” within the meaning of 29 C.F.R. Section 2510.3-101(d)(3)(ii), but that any advice, recommendations or participation by Agent or Lender with respect to any business issues shall not be deemed to give Agent or Lender, nor be deemed an exercise by Agent or Lender of, control over Borrower’s management or policies.

 

7.3      Further Assurances. Borrower and each Material U.S. Subsidiary executing a Joinder Agreement shall from time to time execute, deliver and file, alone or with Agent, any financing statements, security agreements, collateral assignments, notices, control agreements, or other documents to create, perfect or maintain the priority of the Agent’s Lien on the Collateral intended to be created by the Loan Documents. Borrower and each Material U.S. Subsidiary executing a Joinder Agreement shall from time to time procure any instruments or documents as may be reasonably requested by Agent, and take all further action that may be necessary, or that Agent may reasonably request, to perfect and protect the Liens granted hereby and thereby. In addition, and for such purposes only, each Material U.S. Subsidiary executing a Joinder Agreement hereby authorizes Agent to execute and deliver on behalf of such Subsidiary and to file such financing statements (including an indication that the financing statement covers “all assets or all personal property” of such Subsidiary in accordance with Section 9-504 of the UCC), collateral assignments, notices, control agreements, security agreements and other documents without the signature of such Subsidiary either in Agent’s name or in the name of Agent as agent and attorney-in-fact for such Subsidiary. Borrower and each Material U.S. Subsidiary executing a Joinder Agreement shall protect and defend Borrower’s and such Subsidiary’s title to the Collateral and Agent’s Lien thereon against all Persons claiming any interest adverse to Borrower, any Subsidiary or Agent other than Permitted Liens. Borrower shall cause (i) each U.S. Subsidiary that is or becomes a Material U.S. Subsidiary after the Closing Date to enter into a Joinder Agreement by no later than 30 days from the end of the fiscal quarter in which such U.S. Subsidiary becomes a Material U.S. Subsidiary and to execute such other documents as may be reasonably requested by the Agent, and (ii) the capital stock of each Material U.S. Subsidiary or any other Subsidiary that (A) has assets equal to or in excess of 10% of the total assets of Borrower and its Subsidiaries or (B) has revenues equal to or in excess of 10% of the total revenues of Borrower and its Subsidiaries, that is formed after the Closing Date to become subject to a pledge agreement in favor of Agent by no later than 30 days from the end of the fiscal quarter in which such Subsidiary was formed. At no time shall Borrower permit (i) the assets of U.S. Subsidiaries that are not Material U.S. Subsidiaries to exceed 20% of the total assets of Borrower and its Subsidiaries or (ii) the revenues of U.S. Subsidiaries that are not Material U.S. Subsidiaries to exceed 20% of the total revenues of Borrower and its Subsidiaries. Borrower shall designate such U.S. Subsidiaries as “Material U.S. Subsidiaries” as may be required to comply with the foregoing sentence and shall cause such designated Material U.S. Subsidiaries to execute and deliver Joinder Agreements and to otherwise comply with the provisions applicable to Material U.S. Subsidiaries hereunder.

 

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7.4      Indebtedness. Borrower shall not create, incur, assume, guarantee or be or remain liable with respect to any Indebtedness, or permit any Subsidiary so to do, other than Permitted Indebtedness, or prepay any Indebtedness or take any actions which impose on Borrower or any Subsidiary an obligation to prepay any Indebtedness, except for (a) the conversion of Indebtedness into equity securities and the payment of cash in lieu of fractional shares in connection with such conversion, (b) payment of purchase money Indebtedness pursuant to its then applicable payment schedule, (c) prepayment by any Subsidiary of (i) inter-company Indebtedness owed by such Subsidiary to Borrower, or (ii) if such Subsidiary is not a Borrower, intercompany Indebtedness owed by such Subsidiary to another Subsidiary that is not a Borrower, (c) prepayment of Permitted Indebtedness (other than Subordinated Indebtedness except in connection with scheduled payments of principal and interest thereunder) or (d) as otherwise permitted hereunder or approved in writing by Agent.

 

7.5      Collateral. Borrower shall, and shall cause its Subsidiaries to, at all times keep the Collateral, the Intellectual Property and all other property and assets used in Borrower’s and its Subsidiaries’ business or in which Borrower or any Subsidiary now or hereafter holds any interest free and clear from any Liens whatsoever (except for Permitted Liens; provided however, that there shall be no Liens whatsoever on Intellectual Property). Borrower shall not agree, nor permit any of its Subsidiaries to agree, with any Person other than Agent or Lender not to encumber its property other than (i) in connection with Permitted Liens and customary restrictions on the assignment of leases, licenses and other agreements and (ii) as to specific property (other than Intellectual Property) in a transaction(s) described in clauses (b) through (f) in the following sentence. Borrower shall not, nor permit any of its Subsidiaries to, enter into or suffer to exist or become effective any agreement that prohibits or limits the ability of Borrower or any of its Subsidiaries to create, incur, assume or suffer to exist any Lien upon any of its Intellectual Property, whether now owned or hereafter acquired, other than (a) this Agreement and the other Loan Documents, (b) any agreements governing any purchase money Liens or capital lease obligations otherwise permitted hereunder, provided that such prohibition or limitation shall only be effective against the assets financed thereby, (c) customary restrictions on the assignment of leases, licenses and other agreements, (d) restrictions imposed by applicable law, (e) encumbrances and restrictions relating to joint ventures constituting Permitted Investments, and (f) restrictions or conditions imposed by any agreement relating to secured Indebtedness permitted by this Agreement if such restrictions or conditions apply only to the property or assets securing such Indebtedness. Borrower shall cause its Subsidiaries to protect and defend such Subsidiary’s title to its assets from and against all Persons claiming any interest adverse to such Subsidiary, and Borrower shall cause its Subsidiaries at all times to keep such Subsidiary’s property and assets free and clear from any Liens whatsoever (except for Permitted Liens, provided however, that there shall be no Liens whatsoever on Intellectual Property).

 

7.6      Investments. Borrower shall not directly or indirectly acquire or own, or make any Investment in or to any Person, or permit any of its Subsidiaries so to do, other than Permitted Investments.

 

7.7      Distributions. Borrower shall not, and shall not allow any Subsidiary to, (a) repurchase or redeem any class of stock or other equity interest other than pursuant to employee, director or consultant repurchase plans or other similar agreements, provided, however, in each case the repurchase or redemption price does not exceed the original consideration paid for such

 

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stock or equity interest, or (b) declare or pay any cash dividend or make a cash distribution on any class of stock or other equity interest, except that (i) a Subsidiary may pay dividends or make distributions to Borrower or (ii) solely in lieu of the issuance of fractional shares in connection with the exercise of warrants, options, restricted stock units or other securities convertible into or exchangeable for equity interests of the Borrower, or (c) lend money to any employees, officers or directors or guarantee the payment of any such loans granted by a third party in excess of One Hundred Thousand Dollars ($100,000) in the aggregate or (d) waive, release or forgive any Indebtedness owed by any employees, officers or directors in excess of One Hundred Thousand Dollars ($100,000) in the aggregate.

 

7.8      Transfers. Except for Permitted Transfers, Borrower shall not, and shall not allow any Subsidiary to, voluntarily or involuntarily transfer, sell, lease, license, lend or in any other manner convey any equitable, beneficial or legal interest in any material portion of its assets (each such transaction, a “Transfer”).

 

7.9      Mergers or Acquisitions. Borrower shall not merge or consolidate, or permit any of its Subsidiaries to merge or consolidate, with or into any other business organization (other than mergers or consolidations of (a) a Subsidiary which is not a Borrower into another Subsidiary or into Borrower or (b) a Borrower into another Borrower), or acquire, or permit any of its Subsidiaries to acquire, all or substantially all of the capital stock or property of another Person. For the avoidance of doubt, it is agreed by the parties hereto that entry into definitive documents in connection with the transactions contemplated by this paragraph shall not be deemed to be a breach of this Section 7.9 at any time prior to the consummation of the transactions contemplated by such definitive documents.

 

7.10      Taxes. Borrower and its Subsidiaries shall pay when due all material taxes, fees or other charges of any nature whatsoever (together with any related interest or penalties) now or hereafter imposed or assessed against Borrower, any Subsidiary, Agent, Lender or the Collateral or upon Borrower’s ownership, possession, use, operation or disposition thereof or upon Borrower’s rents, receipts or earnings arising therefrom. Borrower and its Subsidiaries shall file on or before the due date therefor all personal property tax returns in respect of the Collateral. Notwithstanding the foregoing, Borrower and its Subsidiaries may contest, in good faith and by appropriate proceedings, taxes for which Borrower and its Subsidiaries maintain adequate reserves therefor in accordance with IFRS.

 

7.11      Corporate Changes. Neither Borrower nor any Subsidiary shall change its corporate name, legal form or jurisdiction of formation without twenty (20) days’ prior written notice to Agent. Neither Borrower nor any Subsidiary shall relocate its chief executive office or its principal place of business unless it has provided prior written notice to Agent.

 

7.12      Deposit Accounts .     Borrower shall not maintain any Deposit Accounts or accounts holding Investment Property, except with respect to which Agent has an Account Control Agreement, provided that (x) no Account Control Agreement shall be required for any Excluded Account and (y) Account Control Agreements with respect to any Deposit Account (other than an Excluded Account) that is opened subsequent to the Closing Date shall be entered into by the Borrower, Agent and the relevant depository bank by no later than thirty (30) days

 

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after the opening of such Deposit Account (which period may be further extended in the reasonable discretion of the Agent).

 

7.13      Subsidiaries. Borrower shall notify Agent of each Subsidiary formed subsequent to the Closing Date in connection with the delivery of its monthly financial statements pursuant to Section 7.1(a) and, within thirty (30) days from date on which any U.S. Subsidiary becomes a Material U.S. Subsidiary, shall cause such Material U.S. Subsidiary to execute and deliver to Agent a Joinder Agreement.

 

7.14      Notification of Event of Default. Borrower shall notify Agent immediately of the occurrence of any Event of Default.

 

7.15      Cash Requirement . Borrower at all times shall maintain unrestricted Cash on deposit in Deposit Account(s) subject to a Lien in favor of the Agent pursuant to the Swiss Security Documents of at least the sum of (i) $5,000,000 plus (ii) Borrower’s accounts payable aged 90 days or greater. For the avoidance of doubt, for purposes of this Agreement and the other Loan Documents, it is agreed by the parties hereto that the Lien on a Deposit Account in favor of the Agent pursuant to an Account Control Agreement shall not be deemed a “restriction” on the Cash on deposit therein.

 

SECTION 8. RIGHT TO INVEST

 

8.1      Lender or its assignee or nominee shall have the right, in its discretion, to participate in any Subsequent Financing in an amount of up to One Million Five Hundred Thousand Dollars ($1,500,000) on the same terms, conditions and pricing afforded to others participating in any such Subsequent Financing. This Section 8.1, and all rights and obligations hereunder, shall survive the repayment of indebtedness under, and otherwise shall survive the expiration or other termination of, the Loan Agreement.

 

SECTION 9. EVENTS OF DEFAULT

 

The occurrence of any one or more of the following events shall be an Event of Default:

 

9.1      Payments. Borrower fails to pay any amount due under this Agreement, the Note(s), or any of the other Loan Documents on the due date; provided, however, that an Event of Default shall not occur on account of a failure to pay due solely to an administrative or operational error of Lender or Borrower’s bank if Borrower had the funds to make the payment when due and makes the payment within three (3) Business Days following Borrower’s knowledge of such failure to pay; or

 

9.2      Covenants. Borrower breaches or defaults in the performance of any covenant or Secured Obligation under this Agreement or any of the other Loan Documents and (a) with respect to a default under any covenant under this Agreement (other than under Sections 6.1, 6.4, 6.5, 7.4, 7.5, 7.6, 7.7, 7.8, 7.9, and 7.14 , and 7.15) or any other Loan Document, such default continues for more than ten (10) days after the earlier of the date on which (i) Agent or Lender has given notice of such default to Borrower and (ii) Borrower has actual knowledge of such default or (b) with respect to a default under any of Sections 6.1, 6.4, 6.5, 7.4, 7.5, 7.6, 7.7, 7.8, 7.9, and 7.14 , and 7.15 the occurrence of such default; or

 

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9.3      Material Adverse Effect. A circumstance has occurred that would reasonably be expected to have a Material Adverse Effect; or

 

9.4      Representations. Any representation or warranty made by Borrower in any Loan Document or in the Warrant shall have been false or misleading in any material respect when made or when deemed made; or

 

9.5      Insolvency. Borrower (A) (i) shall make an assignment for the benefit of creditors; or (ii) shall be unable to pay its debts as they become due, or be unable to pay or perform under the Loan Documents, or shall become insolvent; or (iii) shall file a voluntary petition in bankruptcy; or (iv) shall file any petition, answer, or document seeking for itself any reorganization, arrangement, composition, readjustment, liquidation, dissolution or similar relief under any present or future statute, law or regulation pertinent to such circumstances; or (v) shall seek or consent to or acquiesce in the appointment of any trustee, receiver, or liquidator of Borrower or of all or any substantial part (i.e., 33-1/3% or more) of the assets or property of Borrower; or (vi) shall cease operations of its business as its business has normally been conducted, or terminate substantially all of its employees; or (vii) Borrower or its directors or majority shareholders shall take any action initiating any of the foregoing actions described in clauses (i) through (vi); or (B) either (i) forty-five (45) days shall have expired after the commencement of an involuntary action against Borrower seeking reorganization, arrangement, composition, readjustment, liquidation, dissolution or similar relief under any present or future statute, law or regulation, without such action being dismissed or all orders or proceedings thereunder affecting the operations or the business of Borrower being stayed; or (ii) a stay of any such order or proceedings shall thereafter be set aside and the action setting it aside shall not be timely appealed; or (iii) Borrower shall file any answer admitting or not contesting the material allegations of a petition filed against Borrower in any such proceedings; or (iv) the court in which such proceedings are pending shall enter a decree or order granting the relief sought in any such proceedings; or (v) forty-five (45) days shall have expired after the appointment, without the consent or acquiescence of Borrower, of any trustee, receiver or liquidator of Borrower or of all or any substantial part of the properties of Borrower without such appointment being vacated; or

 

9.6      Attachments; Judgments. Any portion of Borrower’s assets is attached or seized, or a levy is filed against any such assets (and such attachment, seizure or levy is not lifted or stayed within 30 days), or a judgment or judgments is/are entered for the payment of money (not covered by independent third party insurance as to which liability has not been rejected by such insurance carrier), individually or in the aggregate, of at least Two Hundred Fifty Thousand Dollars ($250,000), or Borrower is enjoined or in any way prevented by court order from conducting any part of its business; or

 

9.7      Other Obligations. The occurrence of any default under any agreement or obligation of Borrower involving any Indebtedness in excess of One Million Dollars ($1,000,000).

 

SECTION 10. REMEDIES

 

10.1      General. Upon and during the continuance of any one or more Events of Default, (i) Agent may, at its option, accelerate and demand payment of all or any part of the Secured

 

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Obligations together with a Prepayment Charge and declare them to be immediately due and payable (provided, that upon the occurrence of an Event of Default of the type described in Section 9.5, all of the Secured Obligations shall automatically be accelerated and made due and payable, in each case without any further notice or act), (ii) Agent may, at its option, sign and file in Borrower’s name any and all collateral assignments, notices, control agreements, security agreements and other documents it deems necessary or appropriate to perfect or protect the repayment of the Secured Obligations, and in furtherance thereof, Borrower hereby grants Agent an irrevocable power of attorney coupled with an interest, and (iii) Agent may notify any of Borrower’s account debtors to make payment directly to Agent, compromise the amount of any such account on Borrower’s behalf and endorse Agent’s name without recourse on any such payment for deposit directly to Agent’s account. Agent may exercise all rights and remedies with respect to the Collateral under the Loan Documents or otherwise available to it under the UCC and other applicable law (including Swiss law), including the right to release, hold, sell, lease, liquidate, collect, realize upon, or otherwise dispose of all or any part of the Collateral and the right to occupy, utilize, process and commingle the Collateral. All Agent’s rights and remedies shall be cumulative and not exclusive.

 

10.2      Collection; Foreclosure. Upon the occurrence and during the continuance of any Event of Default, Agent may, at any time or from time to time, apply, collect, liquidate, sell in one or more sales, lease or otherwise dispose of, any or all of the Collateral, in its then condition or following any commercially reasonable preparation or processing, in such order as Agent may elect. Any such sale may be made either at public or private sale at its place of business or elsewhere. Borrower and each Subsidiary executing a Joinder Agreement agree that any such public or private sale may occur upon ten (10) calendar days’ prior written notice to Borrower and or such Subsidiary, as applicable. Agent may require Borrower or any Subsidiary executing a Joinder Agreement to assemble the Collateral and make it available to Agent at a place designated by Agent that is reasonably convenient to Agent and Borrower or such Subsidiary. The proceeds of any sale, disposition or other realization upon all or any part of the Collateral shall be applied by Agent in the following order of priorities:

 

First, to Agent and Lender in an amount sufficient to pay in full Agent’s and Lender’s reasonable costs and professionals’ and advisors’ fees and expenses as described in Section 11.11;

 

Second, to Lender in an amount equal to the then unpaid amount of the Secured Obligations (including principal, interest, and the Default Rate interest), in such order and priority as Agent may choose in its sole discretion; and

 

Finally, after the full and final payment in Cash of all of the Secured Obligations (other than inchoate obligations), to any creditor holding a junior Lien on the Collateral, or to Borrower or its representatives or as a court of competent jurisdiction may direct.

 

Agent shall be deemed to have acted reasonably in the custody, preservation and disposition of any of the Collateral if it complies with the obligations of a secured party under the UCC.

 

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10.3      No Waiver. Agent shall be under no obligation to marshal any of the Collateral for the benefit of Borrower, any Subsidiary or any other Person, and Borrower expressly waives , on behalf of itself and its Subsidiaries, all rights, if any, to require Agent to marshal any Collateral.

 

10.4      Cumulative Remedies. The rights, powers and remedies of Agent hereunder shall be in addition to all rights, powers and remedies given by statute or rule of law and are cumulative. The exercise of any one or more of the rights, powers and remedies provided herein shall not be construed as a waiver of or election of remedies with respect to any other rights, powers and remedies of Agent.

 

SECTION 11. MISCELLANEOUS

 

11.1      Severability. Whenever possible, each provision of this Agreement shall be interpreted in such manner as to be effective and valid under applicable law, but if any provision of this Agreement shall be prohibited by or invalid under such law, such provision shall be ineffective only to the extent and duration of such prohibition or invalidity, without invalidating the remainder of such provision or the remaining provisions of this Agreement.

 

11.2      Notice. Except as otherwise provided herein, any notice, demand, request, consent, approval, declaration, service of process or other communication (including the delivery of Financial Statements) that is required, contemplated, or permitted under the Loan Documents or with respect to the subject matter hereof shall be in writing, and shall be deemed to have been validly served, given, delivered, and received upon the earlier of: (i) the day of transmission by facsimile, electronic mail or hand delivery or delivery by an overnight express service or overnight mail delivery service; or (ii) the third calendar day after deposit in the United States mails, with proper first class postage prepaid, in each case addressed to the party to be notified as follows:

 

If to Agent: HERCULES CAPITAL, INC.
  Legal Department
  400 Hamilton Avenue, Suite 310
  Palo Alto, CA  94301
  Email:
  Facsimile:  
  Telephone:  
   
If to Lender: HERCULES CAPITAL, INC.
  Legal Department
  400 Hamilton Avenue, Suite 310
  Palo Alto, CA  94301
  Email:
  Facsimile:  
  Telephone:  

 

 

If to Borrower: Auris Medical Holding AG

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  Attention: General Counsel
  Bahnhofstrasse 21, 6300 Zug, Switzerland
  Facsimile:  
  Telephone:  

 

or to such other address as each party may designate for itself by like notice.

 

11.3      Entire Agreement; Amendments.

 

(a)     This Agreement and the other Loan Documents constitute the entire agreement and understanding of the parties hereto in respect of the subject matter hereof and thereof, and supersede and replace in their entirety any prior proposals, term sheets, non-disclosure or confidentiality agreements, letters, negotiations or other documents or agreements, whether written or oral, with respect to the subject matter hereof or thereof (including Agent’s revised proposal letter dated May 31, 2016).

 

(b)     Neither this Agreement, any other Loan Document, nor any terms hereof or thereof may be amended, supplemented or modified except in accordance with the provisions of this Section 11.3(b). The Required Lenders and Borrower party to the relevant Loan Document may, or, with the written consent of the Required Lenders, Agent and Borrower party to the relevant Loan Document may, from time to time, (i) enter into written amendments, supplements or modifications hereto and to the other Loan Documents for the purpose of adding any provisions to this Agreement or the other Loan Documents or changing in any manner the rights of Lenders or of Borrower hereunder or thereunder or (ii) waive, on such terms and conditions as the Required Lenders or the Agent, as the case may be, may specify in such instrument, any of the requirements of this Agreement or the other Loan Documents or any default or Event of Default and its consequences; provided, however, that no such waiver and no such amendment, supplement or modification shall (A) forgive the principal amount or extend the final scheduled date of maturity of any Loan, extend the scheduled date of any amortization payment in respect of any Term Loan Advance, reduce the stated rate of any interest or fee payable hereunder, or extend the scheduled date of any payment thereof, in each case without the written consent of each Lender directly affected thereby; (B) eliminate or reduce the voting rights of any Lender under this Section 11.3(b) without the written consent of such Lender; (C) reduce any percentage specified in the definition of Required Lenders, consent to the assignment or transfer by Borrower of any of its rights and obligations under this Agreement and the other Loan Documents, release all or substantially all of the Collateral or release a Borrower or guarantor from its obligations under the Loan Documents, in each case without the written consent of all Lenders; or (D) amend, modify or waive any provision of Section 11.17 without the written consent of the Agent. Any such waiver and any such amendment, supplement or modification shall apply equally to each Lender and shall be binding upon Borrower, any guarantor, Lender, the Agent, and all future holders of the Loans.

 

11.4      No Strict Construction. The parties hereto have participated jointly in the negotiation and drafting of this Agreement. In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto

 

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and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement.

 

11.5      No Waiver. The powers conferred upon Agent and Lender by this Agreement are solely to protect its rights hereunder and under the other Loan Documents and its interest in the Collateral and shall not impose any duty upon Agent or Lender to exercise any such powers. No omission or delay by Agent or Lender at any time to enforce any right or remedy reserved to it, or to require performance of any of the terms, covenants or provisions hereof by Borrower at any time designated, shall be a waiver of any such right or remedy to which Agent or Lender is entitled, nor shall it in any way affect the right of Agent or Lender to enforce such provisions thereafter.

 

11.6      Survival. All agreements, representations and warranties contained in this Agreement and the other Loan Documents or in any document delivered pursuant hereto or thereto shall be for the benefit of Agent and Lender and shall survive the execution and delivery of this Agreement and the expiration or other termination of this Agreement.

 

11.7      Successors and Assigns.

 

(a)     The provisions of this Agreement and the other Loan Documents shall inure to the benefit of and be binding on Borrower and its permitted assigns (if any). Borrower shall not assign its obligations under this Agreement or any of the other Loan Documents without Agent’s express prior written consent, and any such attempted assignment shall be void and of no effect. Agent and Lender may assign, transfer, or endorse its rights hereunder and under the other Loan Documents without prior notice to Borrower, and all of such rights shall inure to the benefit of Agent’s and Lender’s successors and assigns; provided , that, as long as no Event of Default has occurred and is continuing, any such assignment is only admissible if it does not result in a breach of the Swiss Ten Non-Bank Rule; and provided , further , that Borrower shall not be responsible for any costs or indemnities hereunder (including pursuant to Sections 6.3 and 6.4) that arise as a result of the non-compliance by Lender with the Swiss Non-Bank Rules in connection with any such assignment.

 

(b)     Subject to permitted transfers under Section 11.7(a), Lender shall at no time enter into a participation, derivative transaction or any other arrangement with any third party under which Lender transfers all or part of its exposure under this Agreement to that other person, unless under, and throughout the term of, such arrangement:

 

(i) the relationship between Lender and the third party is that of a debtor and creditor (including during the bankruptcy or similar event affecting Lender or Borrower);

 

(ii) the third party has no proprietary interest in the benefit of this Agreement or in any monies received by Lender under or in relation to this Agreement; and

 

(iii) the third party under no circumstances will:

 

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(x)     be subrogated to, or substituted in respect of, Lender's claims under this Agreement; or

 

(y)     otherwise have any contractual relationship with, or rights against, an Obligor under or in relation to this Agreement.

 

11.8      Governing Law. This Agreement and the other Loan Documents have been negotiated and delivered to Agent and Lender in the State of California, and shall have been accepted by Agent and Lender in the State of California. Payment to Agent and Lender by Borrower of the Secured Obligations is due in the State of California. This Agreement and the other Loan Documents shall be governed by, and construed and enforced in accordance with, the laws of the State of California, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction.

 

11.9      Consent to Jurisdiction and Venue. All judicial proceedings (to the extent that the reference requirement of Section 11.10 is not applicable) arising in or under or related to this Agreement or any of the other Loan Documents may be brought in any state or federal court located in the State of California. By execution and delivery of this Agreement, each party hereto generally and unconditionally: (a) consents to nonexclusive personal jurisdiction in Santa Clara County, State of California; (b) waives any objection as to jurisdiction or venue in Santa Clara County, State of California; (c) agrees not to assert any defense based on lack of jurisdiction or venue in the aforesaid courts; and (d) irrevocably agrees to be bound by any judgment rendered thereby in connection with this Agreement or the other Loan Documents. Service of process on any party hereto in any action arising out of or relating to this Agreement shall be effective if given in accordance with the requirements for notice set forth in Section 11.2, and shall be deemed effective and received as set forth in Section 11.2. Nothing herein shall affect the right to serve process in any other manner permitted by law or shall limit the right of either party to bring proceedings in the courts of any other jurisdiction.

 

11.10      Mutual Waiver of Jury Trial / Judicial Reference.

 

(a)     Because disputes arising in connection with complex financial transactions are most quickly and economically resolved by an experienced and expert Person and the parties wish applicable state and federal laws to apply (rather than arbitration rules), the parties desire that their disputes be resolved by a judge applying such applicable laws. EACH OF BORROWER, AGENT AND LENDER SPECIFICALLY WAIVES ANY RIGHT IT MAY HAVE TO TRIAL BY JURY OF ANY CAUSE OF ACTION, CLAIM, CROSS-CLAIM, COUNTERCLAIM, THIRD PARTY CLAIM OR ANY OTHER CLAIM (COLLECTIVELY, “CLAIMS”) ASSERTED BY BORROWER AGAINST AGENT, LENDER OR THEIR RESPECTIVE ASSIGNEE OR BY AGENT, LENDER OR THEIR RESPECTIVE ASSIGNEE AGAINST BORROWER. This waiver extends to all such Claims, including Claims that involve Persons other than Agent, Borrower and Lender; Claims that arise out of or are in any way connected to the relationship among Borrower, Agent and Lender; and any Claims for damages, breach of contract, tort, specific performance, or any equitable or legal relief of any kind, arising out of this Agreement, any other Loan Document.

 

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(b)     If the waiver of jury trial set forth in Section 11.10(a) is ineffective or unenforceable, the parties agree that all Claims shall be resolved by reference to a private judge sitting without a jury, pursuant to Code of Civil Procedure Section 638, before a mutually acceptable referee or, if the parties cannot agree, a referee selected by the Presiding Judge of the Santa Clara County, California. Such proceeding shall be conducted in Santa Clara County, California, with California rules of evidence and discovery applicable to such proceeding.

 

(c)     In the event Claims are to be resolved by judicial reference, either party may seek from a court identified in Section 11.9, any prejudgment order, writ or other relief and have such prejudgment order, writ or other relief enforced to the fullest extent permitted by law notwithstanding that all Claims are otherwise subject to resolution by judicial reference.

 

11.11      Professional Fees. Borrower promises to pay Agent’s and Lender’s documented out of pocket fees and expenses necessary to finalize the loan documentation, including but not limited to reasonable attorneys’ fees, UCC searches, filing costs, and other miscellaneous expenses. In addition, Borrower promises to pay any and all reasonable attorneys’ and other professionals’ fees and expenses incurred by Agent and Lender after the Closing Date in connection with or related to: (a) the Loan; (b) the administration, collection, or enforcement of the Loan; (c) the amendment or modification of the Loan Documents; (d) any waiver, consent, release, or termination under the Loan Documents; (e) the protection, preservation, audit, field exam, sale, lease, liquidation, or disposition of Collateral or the exercise of remedies with respect to the Collateral; (f) any legal, litigation, administrative, arbitration, or out of court proceeding in connection with or related to Borrower or the Collateral, and any appeal or review thereof; and (g) any bankruptcy, restructuring, reorganization, assignment for the benefit of creditors, workout, foreclosure, or other action related to Borrower, the Collateral, the Loan Documents, including representing Agent or Lender in any adversary proceeding or contested matter commenced or continued by or on behalf of Borrower’s estate, and any appeal or review thereof.

 

11.12      Confidentiality. Agent and Lender acknowledge that certain items of Collateral and information provided to Agent and Lender by Borrower are confidential and proprietary information of Borrower, if and to the extent such information either (x) is marked as confidential by Borrower at the time of disclosure, or (y) should reasonably be understood to be confidential (the “Confidential Information”). Accordingly, Agent and Lender agree that Confidential Information it may obtain from Borrower shall not be disclosed to any other Person or entity in any manner whatsoever, in whole or in part, without the prior written consent of Borrower, except that Agent and Lender may disclose any such information: (a) to its own directors, officers, employees, accountants, counsel and other professional advisors and to its Affiliates if Agent or Lender in their sole discretion determines that any such party should have access to such information in connection with such party’s responsibilities in connection with the Loan or this Agreement and, provided that such recipient of such Confidential Information either (i) agrees to be bound by the confidentiality provisions of this paragraph or (ii) is otherwise subject to confidentiality restrictions that reasonably protect against the disclosure and unauthorized use of Confidential Information; (b) if such information is generally available to the public; (c) if required in any report, statement or testimony submitted to any governmental authority having or claiming to have jurisdiction over Agent or Lender or if required in response

 

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to any summons or subpoena or in connection with any litigation, based on the opinion of Agent’s or Lender’s counsel; provided that, to the extent permitted by applicable law, Agent or Lender, as applicable, shall provide Borrower with prior written notice thereof (to the extent practicable) promptly after receipt or such request or determination so that Borrower may seek a protective order or other appropriate remedy; (d) to comply with any legal requirement or law applicable to Agent or Lender; (e) to the extent reasonably necessary in connection with the exercise of any right or remedy under any Loan Document, including Agent’s sale, lease, or other disposition of Collateral after default; (f) to any participant or assignee of Agent or Lender or any prospective participant or assignee; provided, that such participant or assignee or prospective participant or assignee agrees in writing to be bound by this provision prior to disclosure; or (g) otherwise with the prior consent of Borrower; provided, that any disclosure made in violation of this Agreement shall not affect the obligations of Borrower or any of its Affiliates under this Agreement or the other Loan Documents.

 

11.13      Assignment of Rights. Borrower acknowledges and understands that Agent or Lender may, subject to Section 11.7, sell and assign all or part of its interest hereunder and under the Loan Documents to any Person or entity (an “Assignee”). After such assignment the term “Agent” or “Lender” as used in the Loan Documents shall mean and include such Assignee, and such Assignee shall be vested with all rights, powers and remedies of Agent and Lender hereunder with respect to the interest so assigned; but with respect to any such interest not so transferred, Agent and Lender shall retain all rights, powers and remedies hereby given. No such assignment by Agent or Lender shall relieve Borrower of any of its obligations hereunder. Lender agrees that in the event of any transfer by it of the Note(s)(if any), it will endorse thereon a notation as to the portion of the principal of the Note(s), which shall have been paid at the time of such transfer and as to the date to which interest shall have been last paid thereon.

 

11.14      Revival of Secured Obligations. This Agreement and the Loan Documents shall remain in full force and effect and continue to be effective if any petition is filed by or against Borrower for liquidation or reorganization, if Borrower becomes insolvent or makes an assignment for the benefit of creditors, if a receiver or trustee is appointed for all or any significant part of Borrower’s assets, or if any payment or transfer of Collateral is recovered from Agent or Lender. The Loan Documents and the Secured Obligations and Collateral security shall continue to be effective, or shall be revived or reinstated, as the case may be, if at any time payment and performance of the Secured Obligations or any transfer of Collateral to Agent, or any part thereof is rescinded, avoided or avoidable, reduced in amount, or must otherwise be restored or returned by, or is recovered from, Agent, Lender or by any obligee of the Secured Obligations, whether as a “voidable preference,” “fraudulent conveyance,” or otherwise, all as though such payment, performance, or transfer of Collateral had not been made. In the event that any payment, or any part thereof, is rescinded, reduced, avoided, avoidable, restored, returned, or recovered, the Loan Documents and the Secured Obligations shall be deemed, without any further action or documentation, to have been revived and reinstated except to the extent of the full, final, and indefeasible payment to Agent or Lender in Cash.

 

11.15      Counterparts; Electronic Signatures. This Agreement and any amendments, waivers, consents or supplements hereto may be executed in any number of counterparts, and by different parties hereto in separate counterparts, each of which when so delivered shall be deemed an original, but all of which counterparts shall constitute but one and the same

 

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instrument. The words “execution,” “signed,” “signature,” and words of like import this Agreement or in any amendment or other modification hereof (including waivers and consents) shall be deemed to include electronic signatures or the keeping of records in electronic form (including PDF), each of which shall be of the same legal effect, validity or enforceability as a manually executed signature or the use of a paper-based recordkeeping system, as the case may be, to the extent and as provided for in any applicable law, including the Federal Electronic Signatures in Global and National Commerce Act or any state laws based on the Uniform Electronic Transactions Act.

 

11.16      No Third Party Beneficiaries. No provisions of the Loan Documents are intended, nor will be interpreted, to provide or create any third-party beneficiary rights or any other rights of any kind in any Person other than Agent, Lender and Borrower unless specifically provided otherwise herein, and, except as otherwise so provided, all provisions of the Loan Documents will be personal and solely among Agent, Lender and Borrower.

 

11.17      Agency.

 

(a)     Lender hereby irrevocably appoints Hercules Capital, Inc. to act on its behalf as the Agent hereunder and under the other Loan Documents and authorizes the Agent to take such actions on its behalf and to exercise such powers as are delegated to the Agent by the terms hereof or thereof, together with such actions and powers as are reasonably incidental thereto.

 

(b)     Lender agrees to indemnify the Agent in its capacity as such (to the extent not reimbursed by Borrower and without limiting the obligation of Borrower to do so), according to its respective Term Commitment percentages (based upon the total outstanding Term Loan Commitments) in effect on the date on which indemnification is sought under this Section 11.17, from and against any and all liabilities, obligations, losses, damages, penalties, actions, judgments, suits, costs, expenses or disbursements of any kind whatsoever that may at any time be imposed on, incurred by or asserted against the Agent in any way relating to or arising out of, this Agreement, any of the other Loan Documents or any documents contemplated by or referred to herein or therein or the transactions contemplated hereby or thereby or any action taken or omitted by Agent under or in connection with any of the foregoing; The agreements in this Section shall survive the payment of the Loans and all other amounts payable hereunder.

 

(c)     Agent in Its Individual Capacity. The Person serving as the Agent hereunder shall have the same rights and powers in its capacity as a Lender as any other Lender and may exercise the same as though it were not the Agent and the term “Lender” shall, unless otherwise expressly indicated or unless the context otherwise requires, include each such Person serving as the Agent hereunder in its individual capacity.

 

(d)     Exculpatory Provisions. The Agent shall have no duties or obligations except those expressly set forth herein and in the other Loan Documents. Without limiting the generality of the foregoing, the Agent shall not:

 

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(i)     be subject to any fiduciary or other implied duties, regardless of whether any default or any Event of Default has occurred and is continuing;

 

(ii)     have any duty to take any discretionary action or exercise any discretionary powers, except discretionary rights and powers expressly contemplated hereby or by the other Loan Documents that the Agent is required to exercise as directed in writing by Lender, provided that the Agent shall not be required to take any action that, in its opinion or the opinion of its counsel, may expose the Agent to liability or that is contrary to any Loan Document or applicable law; and

 

(iii)     except as expressly set forth herein and in the other Loan Documents, have any duty to disclose, and the Agent shall not be liable for the failure to disclose, any information relating to Borrower or any of its Affiliates that is communicated to or obtained by any Person serving as the Agent or any of its Affiliates in any capacity.

 

(e)     The Agent shall not be liable for any action taken or not taken by it (i) with the consent or at the request of Lender or as the Agent shall believe in good faith shall be necessary, under the circumstances or (ii) in the absence of its own gross negligence or willful misconduct.

 

(f)     The Agent shall not be responsible for or have any duty to ascertain or inquire into (i) any statement, warranty or representation made in or in connection with this Agreement or any other Loan Document, (ii) the contents of any certificate, report or other document delivered hereunder or thereunder or in connection herewith or therewith, (iii) the performance or observance of any of the covenants, agreements or other terms or conditions set forth herein or therein or the occurrence of any default or Event of Default, (iv) the validity, enforceability, effectiveness or genuineness of this Agreement, any other Loan Document or any other agreement, instrument or document or (v) the satisfaction of any condition set forth in Section 4 or elsewhere herein, other than to confirm receipt of items expressly required to be delivered to the Agent.

 

(g)     Reliance by Agent. Agent may rely, and shall be fully protected in acting, or refraining to act, upon, any resolution, statement, certificate, instrument, opinion, report, notice, request, consent, order, bond or other paper or document that it has no reason to believe to be other than genuine and to have been signed or presented by the proper party or parties or, in the case of cables, telecopies and telexes, to have been sent by the proper party or parties. In the absence of its gross negligence or willful misconduct, Agent may conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon any certificates or opinions furnished to Agent and conforming to the requirements of the Loan Agreement or any of the other Loan Documents. Agent may consult with counsel, and any opinion or legal advice of such counsel shall be full and complete authorization and protection in respect of any action taken, not taken or suffered by Agent hereunder or under any Loan Documents in accordance therewith. Agent shall have the right at any time to seek instructions concerning the administration of the Collateral from any court of competent jurisdiction.

 

38  

 

Agent shall not be under any obligation to exercise any of the rights or powers granted to Agent by this Agreement, the Loan Agreement and the other Loan Documents at the request or direction of Lenders unless Agent shall have been provided by Lender with adequate security and indemnity against the costs, expenses and liabilities that may be incurred by it in compliance with such request or direction.

 

11.18      Publicity. None of the parties hereto nor any of its respective member businesses and Affiliates shall, without the other parties’ prior written consent (which shall not be unreasonably withheld or delayed), publicize or use (a) the other party's name (including a brief description of the relationship among the parties hereto), logo or hyperlink to such other parties’ web site, separately or together, in written and oral presentations, advertising, promotional and marketing materials, client lists, public relations materials or on its web site (together, the “ Publicity Materials”); (b) the names of officers of such other parties in the Publicity Materials; and (c) such other parties’ name, trademarks, servicemarks in any news or press release concerning such party; provided however, notwithstanding anything to the contrary herein, no such consent shall be required (i) to the extent necessary to comply with the requests of any regulators, legal requirements or laws applicable to such party, pursuant to any listing agreement with any national securities exchange (so long as such party provides prior notice to the other party hereto to the extent reasonably practicable) and (ii) to comply with Section 11.12.

 

(SIGNATURES TO FOLLOW)

 

39  

 

IN WITNESS WHEREOF, Borrower, Agent and Lender have duly executed and delivered this Loan and Security Agreement as of the day and year first above written.

 

BORROWER:
 
AURIS MEDICAL HOLDING AG
 
By:
Name:
Its:
   
By:
Name:
Its:



 

 

 

 

 

(Signature Page to Loan and Security Agreement)

 

 

 

Accepted in Palo Alto, California:

 

AGENT:
 
HERCULES CAPITAL, INC.
   
By:
Name:
Its:
 

 


(Signature Page to Loan and Security Agreement)

 

 

LENDER:
 
HERCULES CAPITAL, INC.
   
By:
Name:
Its:

 

 

(Signature Page to Loan and Security Agreement)

 

 

Table of Addenda, Exhibits and Schedules

 

Exhibit A: Advance Request
  Attachment to Advance Request
Exhibit B: Term Note
Exhibit C: Name, Locations, and Other Information for Borrower
Exhibit D: Borrower’s Patents, Trademarks, Copyrights and Licenses
Exhibit E: Borrower’s Deposit Accounts and Investment Accounts
Exhibit F: Compliance Certificate
Exhibit G: Joinder Agreement
   
Schedule 1 Subsidiaries
Schedule 1.1 Commitments
Schedule 1A Existing Permitted Indebtedness
Schedule 1B Existing Permitted Investments
Schedule 1C Existing Permitted Liens
Schedule 4.1    Closing Date Loan Documents
Schedule 5.8 Tax Matters
Schedule 5.9 Intellectual Property Claims
Schedule 5.10 Intellectual Property
Schedule 5.11 Borrower Products
Schedule 5.14 Capitalization

 

 

EXHIBIT A
ADVANCE REQUEST

 

To: Agent: Date:

 

 

Hercules Capital, Inc. (the “Agent”)
400 Hamilton Avenue, Suite 310
Palo Alto, CA 94301
Email: legal@herculestech.com
Attn: Mr. Bryan Jadot

 

Auris Medical Holding AG (“Borrower”) hereby requests from Hercules Capital, Inc. (“Lender”) an Advance in the amount of _____________________ Dollars ($________________) on ______________, _____ (the “Advance Date”) pursuant to the Loan and Security Agreement among Borrower, Agent and Lender (the “Agreement”). Capitalized words and other terms used but not otherwise defined herein are used with the same meanings as defined in the Agreement.

 

Please:

 

(a)     Issue a check payable to Borrower     ________

or

(b)     Wire Funds to Borrower’s account     X

 

Bank:  
Address:  
SWIFT:  
IBAN:  
Account Name:  
Contact Person:  
Phone Number:  
To Verify Wire Info:    
E-mail Address:  

 

Borrower represents that the conditions precedent to the Advance set forth in the Agreement are satisfied and shall be satisfied upon the making of such Advance, including but not limited to: (i) that no event that has had or could reasonably be expected to have a Material Adverse Effect has occurred and is continuing; (ii) that the representations and warranties set forth in the Agreement and in the Warrant are and shall be true and correct in all material respects on and as of the Advance Date with the same effect as though made on and as of such date, except to the extent such representations and warranties expressly relate to an earlier date; (iii) that Borrower is in compliance with all the terms and provisions set forth in each Loan Document on its part to be observed or performed; and (iv) that as of the Advance Date, no fact or condition exists that would (or would, with the passage of time, the giving of notice, or both) constitute an Event of Default under the Loan Documents. Borrower understands and acknowledges that Agent has the right to review the financial information supporting this representation and, based upon such review in its sole discretion, Lender may decline to fund the requested Advance.

 

Borrower hereby represents that Borrower’s corporate status and locations have not changed since the date of the Agreement or, if the Attachment to this Advance Request is completed, are as set forth in the Attachment to this Advance Request.

 

 

 

Borrower agrees to notify Agent promptly before the funding of the Loan if any of the matters which have been represented above shall not be true and correct on the Advance Date and if Agent has received no such notice before the Advance Date then the statements set forth above shall be deemed to have been made and shall be deemed to be true and correct as of the Advance Date.

 

Executed as of [          ], [          ].

 

BORROWER:  
 
AURIS MEDICAL HOLDING AG
 
By:
Name:
Its:
   
By:
Name:
Its:

 

 

ATTACHMENT TO ADVANCE REQUEST

 

Dated: _______________________

 

Borrower hereby represents and warrants to Agent that Borrower’s current name and organizational status is as follows:

 

Name: Auris Medical Holding AG
   
Type of organization: Company
   
Jurisdiction of organization: Switzerland
   
Organization file number: CHE-108.297.413

 

Borrower hereby represents and warrants to Agent that the street addresses, cities, states and postal codes of its current locations are as follows:

 

 

 

EXHIBIT B
SECURED TERM NOTE

 

$[  ],000,000          Advance Date:  ___ __, 20[  ]
      Maturity Date:  ___ __, 20[  ]

 

FOR VALUE RECEIVED, Auris Medical Holding AG, a company organized under the laws of Switzerland (the “Borrower”) hereby promises to pay to the order of Hercules Capital, Inc., a Maryland corporation or the holder of this Note (the “Lender”) at 400 Hamilton Avenue, Suite 310, Palo Alto, CA 94301 or such other place of payment as the holder of this Secured Term Promissory Note (this “Promissory Note”) may specify from time to time in writing, in lawful money of the United States of America, the principal amount of [ ] Million Dollars ($[ ],000,000) or such other principal amount as Lender has advanced to Borrower, together with interest at a rate as set forth in Section 2.1(c) of the Loan Agreement based upon a year consisting of 360 days, with interest computed daily based on the actual number of days in each month.

 

This Promissory Note is the Note referred to in, and is executed and delivered in connection with, that certain Loan and Security Agreement dated July 19, 2016, by and among Borrower, the Lender, and Hercules Capital, Inc., a Maryland corporation, as agent (the “Agent”) and the several banks and other financial institutions or entities from time to time party thereto as lender (as the same may from time to time be amended, modified or supplemented in accordance with its terms, the “Loan Agreement”), and is entitled to the benefit and security of the Loan Agreement and the other Loan Documents (as defined in the Loan Agreement), to which reference is made for a statement of all of the terms and conditions thereof. All payments shall be made in accordance with the Loan Agreement. All terms defined in the Loan Agreement shall have the same definitions when used herein, unless otherwise defined herein. An Event of Default under the Loan Agreement shall constitute a default under this Promissory Note.

 

Borrower waives presentment and demand for payment, notice of dishonor, protest and notice of protest under the UCC or any applicable law. Borrower agrees to make all payments under this Promissory Note without setoff, recoupment or deduction and regardless of any counterclaim or defense. This Promissory Note has been negotiated and delivered to Lender and is payable in the State of California. This Promissory Note shall be governed by and construed and enforced in accordance with, the laws of the State of California, excluding any conflicts of law rules or principles that would cause the application of the laws of any other jurisdiction.

 

BORROWER: AURIS MEDICAL HOLDING AG
   
  By:
  Title
   
   
  By:
  Title

:

 

 

 

EXHIBIT C

 

NAME, LOCATIONS, AND OTHER INFORMATION FOR BORROWER

 

1. Borrower represents and warrants to Agent that Borrower’s current name and organizational status as of the Closing Date is as follows:

 

Name: Auris Medical Holding AG
   
Type of organization: Corporation ( Aktiengesellschaft )
   
Jurisdiction of organization: Switzerland
   
Organization file number: CHE-108.297.413

 

2. Borrower represents and warrants to Agent that for five (5) years prior to the Closing Date, Borrower did not do business under any other name or organization or form except the following:

 

Name:     Auris Medical AG

Used until:     April 21, 2014
Type of Organization:     Corporation ( Aktiengesellschaft )

 

Jurisdiction of organization: Switzerland
Organization file Number: CHE-108.297.413

 

Name:     Auris Medical Holding AG

 

Used since April 22, 2014:     
Type of Organization:     Corporation ( Aktiengesellschaft )

Jurisdiction of organization:     Switzerland
Organization file Number: CHE-108.297.413     

 

Borrower’s fiscal year ends on December 31.
Borrower’s federal employer tax identification number is: N/A

 

3. Borrower represents and warrants to Agent that its chief executive office is located at Bahnhofstrasse 21, 6300 Zug, Switzerland.

 

 

 

EXHIBIT D

 

Material PATENTS, TRADEMARKS, COPYRIGHTS AND LICENSES of BORROWER and ITS SUBSIDIARIES

 

Material Patents and Patent Applications

 

See overleaf

 

Material Trademarks and Trademark Applications

 

Trademark Jurisdiction Type Class Holder   Reg-No Priority Date    Status
Auris US Word 5 OTOAG US 4747646 07.12.2010 registered
Auris Medical US Word 5 OTOAG US 4755123 07.12.2010 registered
  CH Word 5 OTOAG CH 682144 05.11.2015 registered
  Int. Word 5 OTOAG IR 1297667 05.11.2015 registered
  EU Figurative 5 OTOAG CTM 014422059 29.07.2015 registered
  CH Figurative 5 OTOAG CTM 59078/2015 29.07.2015 registered
Auris Medical Cochlear Therapies CH Figurative 5,10 OTOAG CH P-514618 15.08.2003 registered
  Int Figurative 5, 10 OTOAG   824015 15.08.2003 registered
  DE Figurative 5, 10 OTOAG IR 824015 15.08.2003 registered
  FR Figurative 5, 10 OTOAG IR 824015 15.08.2003 registered
  US Figurative 5, 10 OTOAG IR 3253841 15.08.2003 registered

 

Material Registered Copyrights

 

None

 

Material Licenses

 

Contrat de Copropriété / Exploitation between L’Institut National de la Santé and et de la Recherche Médicale and Auris Medical AG, dated February 17, 2006 (“Inserm License”)

 

Collaboration Agreement and License Agreement between Xigen SA and Auris Medical AG, dated April 21, 2003 (“Xigen License”)

 

 

 

Material Patents and Patent Applications

 

US Applications and Patents related to AM-101

 

Application No. Filing Date Title Status Publication No. Patent No.
US 10/812,298* 03-29-2004 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY Issued

US 2005/0214338 A1

 

US 8,268,866 B2

US 11/236,941*

 

09-28-2005 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY Abandoned

US 2006/0063802 A1

 

 
US 12/752,556* 04-01-2010 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY Issued

US 2010/0254907 A1

 

US 8,507,525 B2

 

US 14/448,999* 07-31-2014 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY Issued US 2015/0057360 A1

US 9,072,662 B2

 

US 14/728,386* 06-02-2015 METHODS FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY Allowed US 2015/0265552 A1  
US 11/992,632 03-26-2008 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INNER EAR DISORDERS Pending US 2009/0246255 A1  

US 14/317,319

 

06-27-2014 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INNER EAR DISORDERS Issued US 2014/0364836 A1

US 9,066,865 B2

 

US 14/671,524 03-27-2015 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INNER EAR DISORDERS Pending US 2015/0186569 A1  

US 14/671,527

 

03-27-2015 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INNER EAR DISORDERS Pending US 2015/0265532 A1  
US 15/047,956 02-19-2016 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INNER EAR DISORDERS Pending    

*Co-owned with INSERM.

 

International Applications and Patents related to AM-101

 

                 
AI02P001WOAU AU G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 2005229543 2005229543 29.03.2025

 

 

                 
AI02P001WOBR BR F. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 PI0508251-0   29.03.2025
AI02P001WOCA CA G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 2,558,896 2,558,896 29.03.2025
AI02P001WOCN CN G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 200580009886.5 2014092201088240 29.03.2025
AI02P001WOCNT1 CN F. Auris Medical AG, INSERM Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 201510076933.3    
AI02P001WOEPAT AT G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPBE BE G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPBG BG G. Auris Medical AG, Institut Methods for the treatment of tinnitus induced by cochlear 29.03.2005 05736619.7 1729753 29.03.2025

 

 

                 
      national de la santé et de la recherche medicale excitotoxicity        
AI02P001WOEPCH CH G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPCY CY G. Auris Medical AG - alte Adresse, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPCZ CZ G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPDE DE G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPDK DK G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPEE EE G. Auris Medical AG, Institut national de la Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025

 

 

                 
      santé et de la recherche medicale          
AI02P001WOEPEI EP G. Auris Medical AG - alte Adresse, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753  
AI02P001WOEPES ES G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPFI FI G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPFR FR G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 31.03.2025
AI02P001WOEPGB GB G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPGR GR G. Auris Medical AG, Institut national de la santé et de la Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025

 

 

                 
      recherche medicale          
AI02P001WOEPHU HU G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPIE IE G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPIS IS G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPIT IT G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPLT LT G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPLU LU G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPMC MC G. Auris Medical Methods for the treatment of 29.03.2005 05736619.7 1729753 29.03.2025

 

 

                 
      AG, Institut national de la santé et de la recherche medicale tinnitus induced by cochlear excitotoxicity        
AI02P001WOEPNL NL G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPPL PL G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPPT PT G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPRO RO G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPSE SE G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPSI SI G. Auris Medical AG, Institut national de la santé et de la Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025

 

 

                 
      recherche medicale          
AI02P001WOEPSK SK G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOEPTR TR G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 05736619.7 1729753 29.03.2025
AI02P001WOIL IL G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 177490 177490 29.03.2025
AI02P001WOIN IN G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 5128/DELNP/2006 264994 29.03.2025
AI02P001WOJP JP G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 2007-505480 4927706 29.03.2025
AI02P001WOKR KR G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 7022581/2006 10-1189261 29.03.2025
AI02P001WOKRT1 KR G. Auris Medical Methods for the treatment of 29.03.2005 10-2012-7007363 10-1429735 29.03.2025

 

 

                 
      AG, Institut national de la santé et de la recherche medicale tinnitus induced by cochlear excitotoxicity        
AI02P001WOKRT1T1 KR G. Institut national de la santé et de la recherche medicale, Auris Medical AG Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 10-2013-7020276 10-1451414 29.03.2025
AI02P001WOMX MX G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 PA/a/2006/011078 269262 29.03.2025
AI02P001WONZ NZ G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 549399 549399 29.03.2025
AI02P001WORU RU G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 2006 138 153 2380094 29.03.2025
AI02P001WOZA ZA G. Auris Medical AG, Institut national de la santé et de la recherche medicale Methods for the treatment of tinnitus induced by cochlear excitotoxicity 29.03.2005 2006/07161 2006/07161 29.03.2025
AI02P002WOAU AU G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 2005337107 2005337107 28.09.2025

 

 

                 
AI02P002WOBR BR F. Auris Medical AG - alte Adresse, Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 PI0520588-3   28.09.2025
AI02P002WOCA CA G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 2,620,374 2,620,374 28.09.2025
AI02P002WOCNT1 CN F. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 2015102408236    
AI02P002WOEA EA G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264  
AI02P002WOEAAM AM G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEAAZ AZ G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEABY BY G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEAKG KG G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEAKZ KZ G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEAMD MD G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEARU RU G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEATJ TJ G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 200800798 017264 28.09.2025
AI02P002WOEATM TM G. Auris Medical AG - alte Pharmaceutical compositions for the treatment of inner ear 28.09.2005 200800798 017264 28.09.2025

 

 

                 
      Adresse disorders        
AI02P002WOEPAL AL G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPAT AT G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPBA BA G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPBE BE G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPBG BG G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPCH CH G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPCY CY G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPCZ CZ G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPDE DE G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPDK DK G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPEE EE G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPES ES G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPFI FI G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear 28.09.2005 05797324.0-1460 1928405 28.09.2025

 

 

                 
        Disorders        
AI02P002WOEPFR FR G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPGB GB G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPGR GR G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPHR HR G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPHU HU G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPIE IE G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPIS IS G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPIT IT G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPLT LT G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPLU LU G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPLV LV G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPMC MC G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025

 

 

 

 

AI02P002WOEPME ME G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPMK MK G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 30.09.2025
AI02P002WOEPNL NL G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPPL PL G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPPT PT G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPRO RO G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPRS RS G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPSE SE G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPSI SI G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPSK SK G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOEPT1 EP F. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 14001796.3-1460   28.09.2025
AI02P002WOEPTR TR G. Auris Medical AG Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 05797324.0-1460 1928405 28.09.2025
AI02P002WOID ID G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 W00200801065    
AI02P002WOIL IL F. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear 28.09.2005 189622    

 

 

                 
        disorders        
AI02P002WOIN IN F. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 1466/DELNP/2008    
AI02P002WOKR KR G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 7007345/2008 10-1271263 28.09.2025
AI02P002WOMA MA G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 30874 29921 28.09.2025
AI02P002WOMX MX G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 MX/a/2008/004137 303959 28.09.2025
AI02P002WONO NO F. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 20081919   28.09.2025
AI02P002WONZ NZ G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 566062 566062 28.09.2025
AI02P002WOPH PH G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 1-2008-500423 1-2008-500423 28.09.2025
AI02P002WOSGT1 SG G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 201003568-1 161931 28.09.2025
AI02P002WOUA UA G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 a200804948 89858 28.09.2025
AI02P002WOVN VN F. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 1-2008-01005    
AI02P002WOZA ZA G. Auris Medical AG - alte Adresse Pharmaceutical compositions for the treatment of inner ear disorders 28.09.2005 2008/02762 2008/02762 28.09.2025

 

 

EXHIBIT E

 

BORROWER’S DEPOSIT ACCOUNTS AND INVESTMENT ACCOUNTS

 

Deposit Accounts

 

Bank Description Account No Currency
UBS Switzerland AG CHF
UBS Switzerland AG EUR
UBS Switzerland AG USD
UBS Switzerland AG USD

Excluded Account

 

Bank Description Account No Currency
UBS AG USD
       

 

 

EXHIBIT F

 

COMPLIANCE CERTIFICATE

 

Hercules Capital, Inc. (as “Agent”)
400 Hamilton Avenue, Suite 310
Palo Alto, CA 94301

 

Reference is made to that certain Loan and Security Agreement dated July 19, 2016 and the Loan Documents (as defined therein) entered into in connection with such Loan and Security Agreement all as may be amended from time to time (hereinafter referred to collectively as the “Loan Agreement”) by and among Hercules Capital, Inc., the several banks and other financial institutions or entities from time to time party thereto (collectively, the “Lender”) and Hercules Capital, Inc., as agent for the Lender (the “Agent”) and Auris Medical Holding AG (the “Borrower”) as Borrower. All capitalized terms not defined herein shall have the same meaning as defined in the Loan Agreement.

 

The undersigned is an Officer of Borrower, knowledgeable of all Borrower financial matters, and is authorized to provide certification of information regarding Borrower; hereby certifies, in such capacity, that in accordance with the terms and conditions of the Loan Agreement, Borrower is in compliance for the period ending ___________ of all covenants, conditions and terms and hereby reaffirms that all representations and warranties contained therein are true and correct on and as of the date of this Compliance Certificate with the same effect as though made on and as of such date, except to the extent such representations and warranties expressly relate to an earlier date, after giving effect in all cases to any standard(s) of materiality contained in the Loan Agreement as to such representations and warranties. Attached are the required documents supporting the above certification. The undersigned further certifies that these are prepared in accordance with IFRS (except for the absence of footnotes with respect to unaudited financial statement and subject to normal year-end adjustments) and are consistent from one period to the next except as explained below.

 

REPORTING REQUIREMENT REQUIRED CHECK IF ATTACHED
     
Interim Financial Statements Monthly within 30 days  
Interim Financial Statements Quarterly within 45 days  
Audited Financial Statements FYE within 120 days  

 

BANK ACCOUNTS

 

 
Has Borrower opened any new Deposit Accounts or accounts holding Investment Property since the submission of the most recently delivered Compliance Certificate? YES / NO
   
If yes, please provide the following information below:  
   

 

 

Name of Institution

 

Account Number Purpose of Account
1.      
2.      

 

SUBSIDIARIES

 

Has Borrower formed any new Subsidiaries since the submission of the prior monthly financial statements?
 
If yes, please provide the following information below:

 

1. Updated Structure Chart     

2. Name and jurisdiction of newly formed Subsidiary

 

INTERCOMPANY RECEIVABLES

 

Set forth below is a list of all currently outstanding intercompany receivables due to Borrower from any of its Subsidiaries:

 

Obligor

 

Amount  
1.      
2.      

 

OTHER NOTICES     

 

Very Truly Yours,
AURIS MEDICAL HOLDING AG
   
By:
Name:
Its:

 

 

EXHIBIT G

 

FORM OF JOINDER AGREEMENT

 

This Joinder Agreement (the “Joinder Agreement”) is made and dated as of [ ], 20[ ], and is entered into by and between__________________., a ___________ (“Subsidiary”), and HERCULES CAPITAL, INC., a Maryland corporation (as “Agent”).

 

RECITALS

 

A. Subsidiary’s Affiliate, AURIS MEDICAL HOLDING AG (“Borrower”) has entered into that certain Loan and Security Agreement dated July 19, 2016, with the several banks and other financial institutions or entities from time to time party thereto as lender (collectively, the “Lender”) and Agent, as such agreement may be amended (the “Loan Agreement”), together with the other agreements executed and delivered in connection therewith;

 

B. Subsidiary acknowledges and agrees that it will benefit both directly and indirectly from Borrower’s execution of the Loan Agreement and the other agreements executed and delivered in connection therewith;

 

AGREEMENT

 

NOW THEREFORE, Subsidiary and Agent agree as follows:

 

1. The recitals set forth above are incorporated into and made part of this Joinder Agreement. Capitalized terms not defined herein shall have the meaning provided in the Loan Agreement.

 

2. By signing this Joinder Agreement, Subsidiary shall be bound by the terms and conditions of the Loan Agreement the same as if it were the Borrower (as defined in the Loan Agreement) under the Loan Agreement, mutatis mutandis, provided however, that (a) with respect to (i) Section 5.1 of the Loan Agreement, Subsidiary represents that it is an entity duly organized, legally existing and in good standing under the laws of [ ], (b) neither Agent nor Lender shall have any duties, responsibilities or obligations to Subsidiary arising under or related to the Loan Agreement or the other agreements executed and delivered in connection therewith, (c) that if Subsidiary is covered by Borrower’s insurance, Subsidiary shall not be required to maintain separate insurance or comply with the provisions of Sections 6.1 and 6.2 of the Loan Agreement, and (d) that as long as Borrower satisfies the requirements of Section 7.1 of the Loan Agreement, Subsidiary shall not have to provide Agent separate Financial Statements. To the extent that Agent or Lender has any duties, responsibilities or obligations arising under or related to the Loan Agreement or the other agreements executed and delivered in connection therewith, those duties, responsibilities or obligations shall flow only to Borrower and not to Subsidiary or any other Person or entity. By way of example (and not an exclusive list): (i) Agent’s providing notice to Borrower in accordance with the Loan Agreement or as otherwise agreed among Borrower, Agent and Lender shall be deemed provided to Subsidiary; (ii) a Lender’s providing an Advance to Borrower shall be deemed an Advance to Subsidiary; and (iii) Subsidiary shall have no right to request an Advance or make any other demand on Lender.

 

3. Subsidiary agrees not to certificate its equity securities without Agent’s prior written consent, which consent may be conditioned on the delivery of such equity securities to Agent in order to perfect Agent’s security interest in such equity securities.

 

 

 

4. Subsidiary acknowledges that it benefits, both directly and indirectly, from the Loan Agreement, and hereby waives, for itself and on behalf on any and all successors in interest (including without limitation any assignee for the benefit of creditors, receiver, bankruptcy trustee or itself as debtor-in-possession under any bankruptcy proceeding) to the fullest extent provided by law, any and all claims, rights or defenses to the enforcement of this Joinder Agreement on the basis that (a) it failed to receive adequate consideration for the execution and delivery of this Joinder Agreement or (b) its obligations under this Joinder Agreement are avoidable as a fraudulent conveyance.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

 

 

[SIGNATURE PAGE TO JOINDER AGREEMENT]

 

SUBSIDIARY:

 

_________________________________.

 

 

  By:
  Name:
  Title:
   
  Address:
   
   
  Telephone: ___________
  Email: ____________

AGENT:

 

HERCULES CAPITAL, INC.


 

By:
Name:
Title:  



Address:
400 Hamilton Ave., Suite 310
Palo Alto, CA 94301
Email: legal@herculestech.com
Telephone: 650-289-3060

 

 

 

Acknowledged and agreed to:

 

AGENT:

HERCULES CAPITAL, INC.

 

 



By:
Name:
Title:  



 

LENDER:

HERCULES CAPITAL, INC.


By:
Name:
Title:  


 

Address:

 

400 Hamilton Ave., Suite 310
Palo Alto, CA 94301
Facsimile: (650) 473-9194
Telephone: (650) 289-3060

 

 

 

SCHEDULE 1

 

SUBSIDIARIES

 

Auris Medical AG, Falknerstrasse 4, 4001 Basel, Switzerland

 

Auris Medical Ltd., The Black Church, St. Mary’s Place, Dublin 7, D07P4AX, Ireland

 

Auris Medical Inc., 500 North Michigan Avenue, Suite 600, Chicago Illinois 60611, USA

 

Otolanum AG, c/o Auris Medical Holding AG, Bahnhofstrasse 21, 6300 Zug, Switzerland

 

 

 

SCHEDULE 1.1

 

COMMITMENTS

 

LENDER CLOSING DATE TERM COMMITMENT SECOND TRANCHE COMMITMENT Total Commitment
HERCULES CAPITAL, INC. $12,500,000 (Term A Advance) $0 $12,500,000
HERCULES CAPITAL, INC. $0 $7,500,000 (Term B Advance) $7,500,000

 

 

SCHEDULE 1A

 

EXISTING PERMITTED INDEBTEDNESS

 

 

 

SCHEDULE 1B

 

EXISTING PERMITTED INVESTMENTS

 

- All investments disclosed in Note 7 “Property and Equipment” and Note 8 “Intangible assets” to the Borrower’s consolidated financial statements for the 2015 business year (refer to the Annual Report on Form 20F).

 

- All investments required under the terms of the Inserm License and the Xigen License.

 

- Leasehold improvements by AMAG in an amount of up to USD 300,000 at its new facility at Dornacherstrasse 210, Basel, Switzerland.

 

 

 

SCHEDULE 1C

 

EXISTING PERMITTED LIENS

 

-- AMAG has pledged an account held with UBS Switzerland AG in favour of UBS Switzerland AG as a guarantee for indebtedness incurred on corporate credit cards issued to employees. The guarantee amounts to CHF 100,000.

 

-- AMAG has provided security in an amount of CHF 38,000 for payment of the rent under its lease agreement with Privera AG for its offices at Falknerstrasse 4 in Basel and has agreed to provide a security in the amount of CHF 76,700 to PSP Real Estate AG for its new offices at Dornacherstrasse 210 in Basel.

 

 

 

Schedule 4.1

 

CLOSING DATE LOAN DOCUMENTS

 

1 Loan and Security Agreement
1.1 Certificate (dated the closing date)
1.1.A Copy BoD resolution of Borrower
1.1.B Articles of Association of Borrower
1.1.C Excerpt Commercial Register
1.1.D Excerpt Debt Collection Register
2 Warrant
3 Swiss Share Pledge Agreement
3.1  
3.2 Certified copy of the current articles of AMAG
3.3 Resolution of Borrower – refer to 1.1.A
3.4 Resolution of AMAG
3.5 Revised Articles of AMAG
3.6 Public deed re revision of articles
3.7 Application to Commercial Registry
3.8 Share Certificate
3.9 Proxy
4 Swiss Bank Account Claims Security  Assignment Agreement
4.1 Resolution of Borrower – refer to 1.1.A
5 Swiss Security Assignment Agreement
5.1 Resolution of Borrower – refer to 1.1.A
5.2 List of intercompany accounts receivable
   

 

 

SCHEDULE 5.8

 

TAX MATTERS

 

- Since September 2015, the Finanzamt Konstanz, responsible for AMAG’s German VAT declarations, has issued several requests for additional information related to VAT declarations for AMAG’s IMP shipments within the EU and to other countries. Todate the Finanzamt Konstanz has neither challenged the VAT declarations filed nor lodged any claims for additional VAT payments.

 

- The Borrower and AMAG have, in past, omitted to file Form 103 with the Swiss Federal Tax authorities. Form 103 is required to be filed following the approval of the annual report and the accounts by the annual general meeting of shareholders. The Borrower and AMAG have initiated discussions with the competent tax authorities to regularize the situation.

 

 

 

SCHEDULE 5.9

 

INTELLECTUAL PROPERTY CLAIMS

 

- On July, 20, 2015, the USPTO Office declared Patent Interference No. 106,030 involving our issued patent No. 9,066,865 (the “865 Patent”) and Otonomy’s patent application No. 13/848,636. The patent interference identifies our claims No. 1-9 in US Patent No. 9,066,865 as interfering with Otonomy’s claims No. 38, 43, and 46-50. Our 865 Patent relates to methods of treating inner or middle ear diseases with intratympanic injections of poloxamer-based compositions. The claims are directed to the use of fluoroquinolone antibiotics in poloxamer 407 compositions under certain specifications.

 

- AMAG has several areas of disagreement with Xigen, including (i) its interpretation of the scope of the exclusive worldwide license granted to it by Xigen, (ii) the assignment by Xigen of certain of the patents covered by the license and (iii) Xigen’s refusal to grant its consent for the disclosure of certain provisions of its agreement in the prospectus associated with the Borrower’s initial public offering and the filing of a redacted version of the agreement with the SEC. Although the difference in interpretation over the scope of the license has no impact on AMAG’s current or planned use of AM-111 and AMAG has been assured by Xigen and its assignee that the assignment of patents is without prejudice to our license, these areas of disagreement could adversely affect AMAG’s relationship with Xigen and AMAG’s and/or the Borrower’s business, commercialization prospects and financial conditions. Although Xigen has not taken any action as of the date of the date hereof, any resulting litigation could result in substantial legal expenses and potentially the loss of our right to commercialize AM-111. For a discussion of these issues, please refer to “Item 3. Key Information—D. Risk factors —Risks Related to our Reliance on Third Parties of our Annual Report filed on Form 20F.

 

 

 

SCHEDULE 5.10

 

INTELLECTUAL PROPERTY

 

-- AMAG’s rights under the Xigen license may not be transferred to third parties except with the prior written consent of Xigen, provided that Auris may transfer the Xigen License and/or the rights and liabilities arising thereunder to an affiliated company.

 

-- AMAG’s rights under the INSERM license may not be transferred without the prior written consent of INSERM. The INSERM License contains change of control provisions.

 

 

 

SCHEDULE 5.11

 

BORROWER’S PRODUCTS

 

- AMAG has several areas of disagreement with Xigen, including (i) its interpretation of the scope of the exclusive worldwide license granted to it by Xigen, (ii) the assignment by Xigen of certain of the patents covered by the license and (iii) Xigen’s refusal to grant its consent for the disclosure of certain provisions of its agreement in the prospectus associated with the Borrower’s initial public offering and the filing of a redacted version of the agreement with the SEC. Although the difference in interpretation over the scope of the license has no impact on AMAG’s current or planned use of AM-111 and AMAG has been assured by Xigen and its assignee that the assignment of patents is without prejudice to our license, these areas of disagreement could adversely affect AMAG’s relationship with Xigen and AMAG’s and/or the Borrower’s business, commercialization prospects and financial conditions. Although Xigen has not taken any action as of the date of the date hereof, any resulting litigation could result in substantial legal expenses and potentially the loss of our right to commercialize AM-111. For a discussion of these issues, please refer to “Item 3. Key Information—D. Risk factors —Risks Related to our Reliance on Third Parties of our Annual Report filed on Form 20F.

 

 

 

SCHEDULE 5.14

 

CAPITALIZATION

 

Subsidiaries

 

Herein incorporated by reference all subsidiaries listed in Schedule 1.

 

 

 

 

Exhibit 10.2

 

Execution Version

 

THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE US SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), ANY US STATE SECURITIES LAWS, OR UNDER THE SECURITIES LAWS OF ANY OTHER JURISDICTION, AND MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT UNDER THE ACT AND SUCH OTHER LAWS AS MAY BE APPLICABLE OR, SUBJECT TO SECTION 11 HEREOF, AN OPINION OF COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED.

 

WARRANT AGREEMENT

 

To Purchase the Common Shares of

 

AURIS MEDICAL HOLDING AG

 

Dated as of July 19, 2016 (the “ Effective Date ”)

 

WHEREAS, Auris Medical Holding AG, a corporation organized under the laws of Switzerland (the “ Company ”), has entered into a Loan and Security Agreement of even date herewith (as amended and in effect from time to time, the “ Loan Agreement ”) with Hercules Capital, Inc., a Maryland USA corporation, as administrative agent, Hercules Capital, Inc. as a lender (the “ Warrantholder ”), and the other lender parties thereto;

 

WHEREAS, pursuant to the Loan Agreement and as additional consideration to the Warrantholder for, among other things, its agreements therein, the Company has agreed to enter into this Warrant Agreement, providing for the Warrantholder’s right to purchase the Company’s Common Shares (this “ Warrant ”, “ Warrant Agreement ”, or “ Agreement ”);

 

NOW, THEREFORE, in consideration of the Warrantholder having executed and delivered the Loan Agreement and provided the financial accommodations contemplated therein, and in consideration of the mutual covenants and agreements contained herein, the Company and Warrantholder agree as follows:

 

SECTION 1. GRANT OF THE RIGHT TO PURCHASE COMMON SHARES.

 

(a) For value received, the Company hereby grants to the Warrantholder, and the Warrantholder is entitled, upon the terms and subject to the conditions hereinafter set forth, to subscribe for and purchase, from the Company, up to the number of fully paid and non-assessable Common Shares (as defined below) as determined pursuant to Section 1(b) below, at a purchase price per share equal to the Exercise Price (as defined below). The number and Exercise Price of such shares are subject to adjustment as provided in Section 8. As used herein, the following terms shall have the following meanings:

 

Act ” means the US Securities Act of 1933, as amended.

 

Charter ” means the Company’s Articles of Association, or other constitutional document, as may be amended and in effect from time to time.

 

 

 

CHF ” means Swiss Francs.

 

Common Shares ” means the Company’s common shares with a nominal value of CHF 0.40 each, as presently constituted under the Charter, and any class, series or other designation of Company share capital for or into which such common shares may be converted or exchanged in a reorganization, recapitalization or similar transaction.

 

Dollars ” or “ $” means United States Dollars.

 

Exercise Price ” means $3.94, subject to adjustment from time to time in accordance with the provisions of this Warrant; provided that notwithstanding anything herein to the contrary, the Exercise Price shall not be adjusted below the nominal value of the Common Shares subject hereto (currently CHF 0.40).

 

Liquid Sale ” means the closing of a Merger Event in which the consideration received by the Company and/or its shareholders, as applicable, consists solely of cash and/or Marketable Securities.

 

Marketable Securities ” in connection with a Merger Event means securities meeting all of the following requirements: (i) the issuer thereof is then subject to the reporting requirements of Section 13 or Section 15(d) of the US Securities Exchange Act of 1934, as amended (the “ Exchange Act ”), or any comparable applicable law(s) of any other jurisdiction, and is then current in its filing of all required reports and other information under the Act and the Exchange Act or such comparable law(s); (ii) the class and series, or other designation, of shares or other security of the issuer that would be received by the Warrantholder in connection with the Merger Event were the Warrantholder to exercise this Warrant on or prior to the closing thereof is then traded on a national securities exchange or over-the-counter market in the US or other jurisdiction, and (iii) following the closing of such Merger Event, Warrantholder would not be restricted from publicly re-selling all of the issuer’s shares and/or other securities that would be received by Warrantholder in such Merger Event were Warrantholder to exercise this Warrant in full on or prior to the closing of such Merger Event, except to the extent that any such restriction (x) arises solely under US federal or state securities laws, rules or regulations, or the securities laws of any other jurisdiction, and (y) does not extend beyond six (6) months from the closing of such Merger Event.

 

Merger Event ” means any of the following: (i) a sale, lease or other transfer of all or substantially all assets of the Company, (ii) any merger or consolidation involving the Company in which the Company is not the surviving entity or in which the outstanding Common Shares of the Company are otherwise converted into or exchanged for share capital or other securities or property of another entity and in which the holders of a majority of the outstanding Common Shares of the Company immediately prior to such merger or consolidation do not hold a majority of the voting power of the surviving entity or other entity immediately following such merger or consolidation, or (iii) any sale by holders of the outstanding voting equity securities of the Company in a single transaction or series of related transactions of shares constituting a majority of the outstanding combined voting power of the Company.

 

Purchase Price ” means, with respect to any exercise of this Warrant, an amount equal to the then-effective Exercise Price multiplied by the number of Common Shares as to which this Warrant is then exercised.

 

2  

 

Rule 144 ” means Rule 144 promulgated under the Act, as amended.

 

US ” means the United States of America.

 

(b) Number of Shares . This Warrant shall be exercisable for the Initial Shares, plus the Additional Shares, if any.

 

(i) Initial Shares . As used herein, “ Initial Shares ” means such number of Common Shares as shall equal (x) $617,500.00, divided by (y) the Exercise Price, subject to adjustment from time to time in accordance with the provisions of this Warrant.

 

(ii) Additional Shares . Upon the making (if any) of the first Term B Loan Advance (as defined in the Loan Agreement) to the Company in any amount, this Warrant automatically shall become exercisable for such number of additional Common Shares as shall equal (x) $332,500.00, divided by (y) the Exercise Price, subject to adjustment thereafter from time to time in accordance with the provisions of this Warrant (the “ Additional Shares ”).

 

SECTION 2. TERM OF THE AGREEMENT.

 

The term of this Agreement and the right to purchase Common Shares as granted herein shall commence on the Effective Date and, subject to Section 8(a) below, shall be exercisable for a period ending upon the seventh (7 th ) anniversary of the Effective Date.

 

SECTION 3. EXERCISE OF THE PURCHASE RIGHTS.

 

(a) Exercise . The purchase rights set forth in this Agreement are exercisable by the Warrantholder, in whole or in part, at any time, or from time to time, prior to the expiration of the term set forth in Section 2, by tendering to the Company at its principal office a notice of exercise in the form attached hereto as Exhibit I (the “ Notice of Exercise ”), duly completed and executed; provided , that any single exercise shall be for no less than $300,000 of Common Shares (or if, on account of one or more prior exercises of this Warrant, the Warrantholder’s purchase rights hereunder shall then be for less than $300,000 of Common Shares, such exercise shall be for all Common Shares then subject to purchase hereunder). Promptly upon receipt of the Notice of Exercise and the payment of the Purchase Price in accordance with the terms set forth below, and in no event later than three business (3) days thereafter, the Company shall issue to the Warrantholder the number of Common Shares purchased either by delivering a certificate to the Warrantholder or its designee evidencing such Common Shares or by causing its transfer agent to establish book entries evidencing such Common Shares, and in any case shall execute the acknowledgment of exercise in the form attached hereto as Exhibit II (the “ Acknowledgment of Exercise ”) indicating the number of shares which remain subject to future purchases under this Warrant, if any.

 

The Purchase Price shall be paid in cash by wire transfer (in Dollars or Swiss francs) to a bank account in Switzerland specified by the Company (the “Bank Account”). Upon partial exercise of this Warrant prior to the expiration or earlier termination hereof, the Company shall, upon request, promptly issue an amended Agreement representing the remaining number of shares purchasable hereunder. All other terms and conditions of such amended Agreement shall be identical to those contained herein, including, but not limited to the Effective Date hereof.

 

(b) Exercise Prior to Expiration and Liquid Sale . (x) To the extent this Warrant is not previously exercised as to all Common Shares subject hereto prior to its expiration, and if the

 

3  

 

then-current fair market value of one Common Share is greater than the Exercise Price then in effect, this Warrant shall be deemed automatically exercised on a cash basis pursuant to Section 3(a) (even if not surrendered) as of the business day prior to its expiration determined in accordance with Section 2 and (y) to the extent this Warrant is not previously exercised as to all Common Shares subject thereto prior to a Liquid Sale, where the fair market value per Common Share (as determined as of the closing of such Liquid Sale) to be paid to the holders thereof is greater than the Exercise Price then in effect, this Warrant shall be deemed automatically exercised on a cash basis pursuant to Section 3(a) (even if not surrendered) as of the business day prior to the closing of such Liquid Sale. To the extent this Warrant or any portion hereof is deemed automatically exercised pursuant to this Section 3(b), the Company agrees to promptly notify the Warrantholder of the number of Common Shares if any, the Warrantholder is to receive by reason of such automatic exercise. In the case of each such automatic exercise, promptly following the Warrantholder’s receipt of such notification from the Company, the Warrantholder shall deliver a Notice of Exercise to the Company and payment of the Purchase Price to the Bank Account. Following receipt of the Purchase Price and the Notice of Exercise, the Company agrees to issue to the Warrantholder the number of Common Shares if any, the Warrantholder is to receive by reason of such automatic exercise by causing its transfer agent to establish book entries evidencing such Common Shares.

 

For purposes of the automatic exercise referenced above, the current fair market value of Common Shares and Marketable Securities shall mean with respect to each Common Share or Marketable Security:

 

(i) at all times when the Common Shares or relevant Marketable Security, as applicable, shall be traded on a national securities exchange, inter-dealer quotation system or over-the-counter bulletin board service, the volume-weighted average of the closing prices over a thirty (30) trading day period ending three days before the day the current fair market value of the securities is being determined; or

 

(ii) if the current fair market value of a Common Shares or relevant Marketable Security, as applicable, cannot be determined as described in the foregoing clause (i), the current fair market value of a Common Shares or relevant Marketable Security, as applicable, shall be determined in good faith by the Company’s Board of Directors.

 

SECTION 4. RESERVATION OF SHARES.

 

During the term of this Agreement, the Company will at all times have authorized and reserved a sufficient number of its Common Shares as contingent capital ( bedingtes Kapital ) to provide for the exercise of the rights to purchase Common Shares as provided for herein. The Company acknowledges that compensation for damages may not be sufficient remedy for the Warrantholder in case of the Company’s failure to comply with its obligation under this Section 4 and therefore expressly confirms that the Warrantholder may in such case request specific performance ( Realerfüllung ) upon due exercise of its purchase rights pursuant to Section 3 hereof from time to time by obligating the Company to deliver such number of shares as would have been issued to the Warrantholder in connection with such exercise of its purchase rights from time to time.

 

SECTION 5. NO FRACTIONAL SHARES OR SCRIP.

 

No fractional shares or scrip representing fractional shares shall be issued upon the exercise of this Agreement, but in lieu of any fractional share the Company shall make a cash

 

4  

 

payment therefor in amount equal to (a) such fraction, multiplied by (b)(i) the then-fair market value of a Common Share as determined in accordance with Section 3(b) above, minus (ii) the then-effective Exercise Price.

 

SECTION 6. NO RIGHTS AS SHAREHOLDER

 

Without limitation of any provision hereof, Warrantholder agrees that this Agreement does not entitle the Warrantholder to any voting rights or other rights as a shareholder of the Company prior to the Warrantholder’s ownership of the respective Common Shares.

 

SECTION 7. [RESERVED].

 

SECTION 8. ADJUSTMENT RIGHTS.

 

The Exercise Price and the number of Common Shares purchasable hereunder are subject to adjustment from time to time, as follows:

 

(a) Merger Event . In connection with a Merger Event that is a Liquid Sale, this Warrant shall, on and after the closing thereof, automatically and without further action on the part of any party or other person, represent the right to receive the consideration payable on or in respect of all Common Shares that are issuable hereunder as of immediately prior to the closing of such Liquid Sale less the Purchase Price for all such Common Shares (such consideration to include both the consideration payable at the closing of such Liquid Sale and all deferred consideration payable thereafter, if any, including, but not limited to, payments of amounts deposited at such closing into escrow and payments in the nature of earn-outs, milestone payments or other performance-based payments (“ Deferred Payments ”)), and such Liquid Sale consideration shall be paid to Warrantholder as and when it is paid to the holders of the outstanding Common Shares. To the extent that the maximum aggregate consideration per outstanding Common Share (including, without limitation, all Deferred Payments) in such Liquid Sale (assuming for such determination that all Common Shares for which this Warrant is then exercisable are issued and outstanding) that could, without discount to present value, be paid for, on or in respect of each such outstanding Common Share in accordance with the definitive transaction documents therefor is equal to or less than the Exercise Price in effect as of immediately prior to the initial closing thereof, then this Warrant shall, effective on and as of such initial closing, terminate and be of no further force or effect.

 

In connection with a Merger Event that is not a Liquid Sale, the Company shall cause the successor or surviving entity to assume this Warrant and the obligations of the Company hereunder on the closing thereof, and thereafter this Warrant shall be exercisable for the same number and type of securities or other property as the Warrantholder would have received in consideration for the Common Shares issuable hereunder had it exercised this Warrant in full as of immediately prior to such closing, at an aggregate Exercise Price no greater than the aggregate Exercise Price in effect as of immediately prior to such closing, and subject to further adjustment from time to time in accordance with the provisions of this Warrant. The provisions of this Section 8(a) shall similarly apply to successive Merger Events.

 

(b) Reclassification of Shares . Except for Merger Events subject to Section 8(a), if the Company at any time shall, by combination, reclassification, exchange or subdivision of securities or otherwise, change any of the securities as to which purchase rights under this Agreement exist into the same or a different number of securities of any other class or classes of securities, this Agreement shall thereafter represent the right to acquire such number and kind of securities as would have been issuable as the result of such change with respect to the securities which were subject to the purchase rights under this Agreement immediately prior to such

 

5  

 

combination, reclassification, exchange, subdivision or other change. The provisions of this Section 8(b) shall similarly apply to successive combination, reclassification, exchange, subdivision or other change.

 

(c) Subdivision or Combination of Shares . If the Company at any time shall combine or subdivide its Common Shares, (i) in the case of a subdivision, the Exercise Price shall be proportionately decreased and the number of shares for which this Warrant is exercisable shall be proportionately increased, or (ii) in the case of a combination, the Exercise Price shall be proportionately increased and the number of shares for which this Warrant is exercisable shall be proportionately decreased.

 

(d) Stock Dividends . If the Company at any time while this Agreement is outstanding and unexpired shall:

 

(i) pay a dividend with respect to the outstanding Common Shares payable in additional Common Shares, then the Exercise Price shall be adjusted, from and after the date of determination of shareholders entitled to receive such dividend or distribution, to that price determined by multiplying the Exercise Price in effect immediately prior to such date of determination by a fraction (A) the numerator of which shall be the total number of Common Shares outstanding immediately prior to such dividend or distribution, and (B) the denominator of which shall be the total number of Common Shares outstanding immediately after such dividend or distribution, and the number of Common Shares for which this Warrant is exercisable shall be proportionately increased; or

 

(ii) make any other dividend or distribution on or with respect to Common Shares, except any dividend or distribution (A) in cash, or (B) specifically provided for in any other clause of this Section 8, then, in each such case, provision shall be made by the Company such that the Warrantholder shall receive upon exercise or conversion of this Warrant a proportionate share of any such distribution as though it were the holder of the Common Shares as of the record date fixed for the determination of the shareholders of the Company entitled to receive such distribution.

 

(e) Notice of Certain Events . If: (i) the Company shall declare any dividend or distribution upon its outstanding Common Shares, payable in capital shares or other Company securities, cash, or other property (provided that Warrantholder in its capacity as lender under the Loan Agreement consents to such dividend); (ii) the Company shall offer for subscription pro rata to the holders of its Common Shares any additional shares of stock of any class or other rights; (iii) there shall be any Merger Event; or (iv) there shall be any voluntary dissolution, liquidation or winding up of the Company; then, in connection with each such event, the Company shall give the Warrantholder notice thereof at the same time and in the same manner as it gives notice thereof to the holders of outstanding Common Shares.

 

SECTION 9. REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE COMPANY.

 

(a) Reservation of Common Shares . The Company covenants and agrees that all Common Shares, if any, that may be issued upon the exercise of the rights represented by this Warrant will, upon issuance, be validly issued and outstanding, fully paid and non-assessable. The Company further covenants and agrees that the Company will, at all times during the term hereof, have authorized and reserved, free from preemptive rights, a sufficient number of Common Shares to provide for the exercise of the rights represented by this Warrant. If at any time during the term hereof the number of authorized but unissued Common Shares shall not be

 

6  

 

sufficient to permit exercise of this Warrant in full, the Company will take such corporate action as may, in the opinion of its counsel, be necessary to increase its authorized but unissued Common Shares to such number of shares as shall be sufficient for such purposes.

 

(b) Due Authority . The execution and delivery by the Company of this Agreement and the performance of all obligations of the Company hereunder, including the issuance to Warrantholder of the right to acquire the Common Shares, have been duly authorized by all necessary corporate action on the part of the Company. This Agreement: (1) does not violate the Company's Charter or current bylaws; (2) except as could not reasonably be expected to have a Material Adverse Effect (as defined in the Loan Agreement), does not contravene any law or governmental rule, regulation or order applicable to it; and (3) except as could not reasonably be expected to have a Material Adverse Effect, does not and will not contravene any provision of, or constitute a default under, any indenture, mortgage, contract or other instrument to which it is a party or by which it is bound. This Agreement constitutes a legal, valid and binding agreement of the Company, enforceable in accordance with its terms, except as may be limited by bankruptcy, insolvency, reorganization, moratorium or similar laws relating to or affecting creditors’ rights generally (including, without limitation, fraudulent conveyance laws) and by general principles of equity, regardless of whether considered in a proceeding in equity or at law.

 

(c) Consents and Approvals . No consent or approval of, giving of notice to, registration with, or taking of any other action in respect of any state, federal or other governmental authority or agency is required with respect to the execution, delivery and performance by the Company of its obligations under this Agreement, except for any filing of notices pursuant to Regulation D under the Act and any filing required by applicable state securities law, which filings will be effective by the time required thereby.

 

(d) [Intentionally Omitted] .

 

(e) Registration Rights . No later than April 30, 2017, the Company agrees to use its commercially reasonable efforts to effect the registration under the Act of the Common Shares issued upon exercise of this Warrant.

 

(f) Exempt Transaction . Subject to the accuracy of the Warrantholder's representations in Section 10, the issuance of the Common Shares upon exercise of this Agreement will constitute a transaction exempt from (i) the registration requirements of Section 5 of the Act, in reliance upon Section 4(2) thereof, (ii) the qualification requirements of applicable US state securities laws, and (iii) the registration and/or qualification requirements of any other securities laws applicable to the Company.

 

(g) [Intentionally Omitted].

 

(h) Information Rights . At all times (if any) prior to the earlier to occur of (x) the date on which all Common Shares issued on exercise of this Warrant have been sold, or (y) the expiration or earlier termination of this Warrant, when the Company shall not be required to file reports pursuant to Section 13 or 15(d) of the Exchange Act or comparable applicable law of another jurisdiction or shall not have timely filed all such required reports, Warrantholder shall be entitled to receive the same information as is distributed by the Company to all of its shareholders. All such information shall be held and treated by the Warrantholder in confidence in accordance with the provisions of Section 11.12 of the Loan Agreement (regardless of whether the Loan Agreement is then in effect).

 

(i) Rule 144 Compliance . The Company shall, at all times prior to the earlier to occur of (x) the date of sale or other disposition by Warrantholder of this Warrant or all Common Shares issued on exercise of this Warrant or (y) the expiration or earlier termination of this Warrant if the Warrant has not been exercised in full or in part on such date, use all commercially reasonable efforts to timely file all reports required under the Exchange Act and otherwise

 

7  

 

cooperate with the Warrantholder if the Warrantholder decides to sell or otherwise dispose of this Warrant and the Common Shares issued on exercise hereof pursuant to Rule 144. If the Warrantholder proposes to sell Common Shares issuable upon the exercise of this Agreement in compliance with Rule 144, then, upon Warrantholder’s written request to the Company, the Company shall furnish to the Warrantholder, within five (5) business days after receipt of such request, a written statement confirming the Company’s compliance with the filing and other requirements of such Rule.

 

SECTION 10. REPRESENTATIONS AND COVENANTS OF THE WARRANTHOLDER.

 

This Agreement has been entered into by the Company in reliance upon the following representations and covenants of the Warrantholder:

 

(a) Investment Purpose . This Warrant and the shares issued on exercise hereof will be acquired for investment and not with a view to the sale or distribution of any part thereof in violation of applicable US federal and state securities laws, and the Warrantholder has no present intention of selling or engaging in any public distribution of the same except pursuant to a registration or exemption.

 

(b) Private Issue . The Warrantholder understands (i) that the Common Shares issuable upon exercise of this Agreement are not, as of the Effective Date, registered under the Act or qualified under applicable US state securities laws, and (ii) that the Company's reliance on exemption from such registration is predicated on the representations set forth in this Section 10.

 

(c) Financial Risk . The Warrantholder has such knowledge and experience in financial and business matters as to be capable of evaluating the merits and risks of its investment, and has the ability to bear the economic risks of its investment.

 

(d) Accredited Investor . Warrantholder is an "accredited investor" within the meaning of Rule 501 of Regulation D promulgated under the Act, as presently in effect (“ Regulation D ”).

 

(e) No Short Sales . Warrantholder has not at any time on or prior to the Effective Date engaged in any short sales or equivalent transactions in the Common Shares. Warrantholder agrees that at all times from and after the Effective Date and on or before the expiration or earlier termination of this Warrant, it shall not engage in any short sales or equivalent transactions in the Common Shares.

 

SECTION 11. TRANSFERS.

 

Subject to compliance with applicable US federal and state securities laws, this Agreement and all rights hereunder are transferable, in whole or in part, without charge to the holder hereof (except for transfer taxes) upon surrender of this Agreement properly endorsed. Each taker and holder of this Agreement, by taking or holding the same, consents and agrees that this Agreement, when endorsed in blank, shall be deemed negotiable, and that the holder hereof, when this Agreement shall have been so endorsed, shall be treated by the Company and all other persons dealing with this Agreement as the absolute owner hereof for any purpose and as the person entitled to exercise the rights represented notified to the Company by a notice of transfer in the form attached hereto as Exhibit III (the " Transfer Notice "), at its principal offices and the payment to the Company of all transfer taxes and other governmental charges imposed on such transfer. Until the Company receives such Transfer Notice, the Company may treat the initial owner hereof as the owner for all purposes. Notwithstanding anything herein or in any legend to the contrary, the Company shall not require an opinion of counsel in connection with any sale, assignment or other transfer by Warrantholder of this Warrant (or any portion hereof or any interest herein) or of any Common Shares issued upon any exercise hereof to an affiliate (as

 

8  

 

defined in Regulation D) of Warrantholder, provided that the restrictive legend will remain on such transferred Warrant, and provided further that such affiliate shall be, at the time of such sale, assignment or transfer, an “accredited investor” as defined in Regulation D and shall, at the Company’s request, represent same to the Company in writing.

 

SECTION 12. MISCELLANEOUS.

 

(a) Effective Date . The provisions of this Agreement shall be construed and shall be given effect in all respects as if it had been executed and delivered by the Company on the date hereof. This Agreement shall be binding upon any successors or assigns of the Company.

 

(b) Remedies . In the event of any default hereunder, the non-defaulting party may proceed to protect and enforce its rights either by suit in equity and/or by action at law, including but not limited to an action for damages as a result of any such default, and/or an action for specific performance for any default where Warrantholder will not have an adequate remedy at law and where damages will not be readily ascertainable.

 

(c) No Impairment of Rights . The Company will not, by amendment of its Charter or through any other means, avoid or seek to avoid the observance or performance of any of the terms of this Agreement, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate in order to protect the rights of the Warrantholder against impairment.

 

(d) Additional Documents . The Company agrees to supply such other documents as the Warrantholder may from time to time reasonably request.

 

(e) Attorneys’ Fees . In any litigation, arbitration or court proceeding between the Company and the Warrantholder relating hereto, the prevailing party shall be entitled to reasonable attorneys’ fees and expenses and all costs of proceedings incurred in enforcing this Agreement. For the purposes of this Section 12(e), reasonable attorneys’ fees shall include without limitation fees incurred in connection with the following: (i) contempt proceedings; (ii) discovery; (iii) any motion, proceeding or other activity of any kind in connection with an insolvency proceeding; (iv) garnishment, levy, and debtor and third party examinations; and (v) post-judgment motions and proceedings of any kind, including without limitation any activity taken to collect or enforce any judgment.

 

(f) Severability . In the event any one or more of the provisions of this Agreement shall for any reason be held invalid, illegal or unenforceable, the remaining provisions of this Agreement shall be unimpaired, and the invalid, illegal or unenforceable provision shall be replaced by a mutually acceptable valid, legal and enforceable provision, which comes closest to the intention of the parties underlying the invalid, illegal or unenforceable provision.

 

(g) Notices . Except as otherwise provided herein, any notice, demand, request, consent, approval, declaration, service of process or other communication that is required, contemplated, or permitted under this Agreement or with respect to the subject matter hereof shall be in writing, and shall be deemed to have been validly served, given, delivered, and received upon the earlier of: (a) personal delivery to the party to be notified, (b) when sent by confirmed telex, electronic transmission or facsimile if sent during normal business hours of the recipient, if not, then on the next business day, (c) five days after having been sent by registered or certified mail, return receipt requested, postage prepaid, or (d) one day after deposit with a nationally recognized overnight courier, specifying next day delivery, with written verification of receipt, and shall be addressed to the party to be notified as follows:

 

If to Warrantholder:

 

9  

 

Hercules CAPITAL, INC.

Legal Department 

400 Hamilton Avenue, Suite 310 

Palo Alto, CA 94301

Facsimile:

Telephone:

 

If to the Company:

 

Auris Medical Holding AG

Attention: General Counsel 

Bahnhofstrasse 21

6300 Zug, Switzerland 

Facsimile:

Telephone:

Email:

 

or to such other address as each party may designate for itself by like notice.

 

(h) Entire Agreement; Amendments . This Agreement constitutes the entire agreement and understanding of the parties hereto in respect of the subject matter hereof, and supersedes and replaces in their entirety any prior proposals, term sheets, letters, negotiations or other documents or agreements, whether written or oral, with respect to the subject matter hereof. None of the terms of this Agreement may be amended except by an instrument executed by each of the parties hereto.

 

(i) Headings . The various headings in this Agreement are inserted for convenience only and shall not affect the meaning or interpretation of this Agreement or any provisions hereof.

 

(j) Advice of Counsel . Each of the parties represents to each other party hereto that it has discussed (or had an opportunity to discuss) with its counsel this Agreement and, specifically, the provisions of Sections 12(n), 12(o) and 12(p).

 

(k) No Strict Construction . The parties hereto have participated jointly in the negotiation and drafting of this Agreement. In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement.

 

(l) No Waiver . No omission or delay by Warrantholder at any time to enforce any right or remedy reserved to it, or to require performance of any of the terms, covenants or provisions hereof by Warrantholder at any time designated, shall be a waiver of any such right or remedy to which Warrantholder is entitled, nor shall it in any way affect the right of Warrantholder to enforce such provisions thereafter during the term of this Agreement.

 

(m) Survival . All agreements, representations and warranties contained in this Agreement or in any document delivered pursuant hereto shall be for the benefit of Warrantholder and shall survive the execution and delivery of this Agreement and the expiration or other termination of this Agreement.

 

(n) Governing Law . This Agreement shall be governed by, and construed and enforced in accordance with, the laws of the State of New York, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction. For the avoidance of doubt, matters

 

10  

 

involving the rights of shareholders and the issuance of Common Shares shall be governed by the laws of Switzerland.

 

(o) Consent to Jurisdiction and Venue . All judicial proceedings arising in or under or related to this Agreement may be brought in any state or federal court of competent jurisdiction located in the State of New York. By execution and delivery of this Agreement, each party hereto generally and unconditionally: (a) consents to personal jurisdiction in New York County, State of New York; (b) waives any objection as to jurisdiction or venue in New York County, State of New York; (c) agrees not to assert any defense based on lack of jurisdiction or venue in the aforesaid courts; and (d) irrevocably agrees to be bound by any judgment rendered thereby in connection with this Agreement. Service of process on any party hereto in any action arising out of or relating to this Agreement shall be effective if given in accordance with the requirements for notice set forth in Section 12(g), and shall be deemed effective and received as set forth in Section 12(g). Nothing herein shall affect the right to serve process in any other manner permitted by law or shall limit the right of either party to bring proceedings in the courts of any other jurisdiction.

 

(p) Mutual Waiver of Jury Trial . Because disputes arising in connection with complex financial transactions are most quickly and economically resolved by an experienced and expert person and the parties wish applicable state and federal laws to apply (rather than arbitration rules), the parties desire that their disputes arising under or in connection with this Warrant be resolved by a judge applying such applicable laws. EACH OF THE COMPANY AND WARRANTHOLDER SPECIFICALLY WAIVES ANY RIGHT IT MAY HAVE TO TRIAL BY JURY OF ANY CAUSE OF ACTION, CLAIM, CROSS-CLAIM, COUNTERCLAIM, THIRD PARTY CLAIM OR ANY OTHER CLAIM (COLLECTIVELY, "CLAIMS") ASSERTED BY THE COMPANY AGAINST WARRANTHOLDER OR ITS ASSIGNEE OR BY WARRANTHOLDER OR ITS ASSIGNEE AGAINST THE COMPANY RELATING TO THIS WARRANT. This waiver extends to all such Claims, including Claims that involve persons or entities other the Company and Warrantholder; Claims that arise out of or are in any way connected to the relationship between the Company and Warrantholder; and any Claims for damages, breach of contract, specific performance, or any equitable or legal relief of any kind, arising out of this Agreement.

 

(q) Counterparts . This Agreement and any amendments, waivers, consents or supplements hereto may be executed in any number of counterparts (including by facsimile or electronic delivery (PDF), and by different parties hereto in separate counterparts, each of which when so delivered shall be deemed an original, but all of which counterparts shall constitute but one and the same instrument.

 

(r) Specific Performance . The parties hereto hereby declare that it is impossible to measure in money the damages which will accrue to Warrantholder by reason of the Company’s failure to perform any of the obligations under this Agreement and agree that the terms of this Agreement shall be specifically enforceable by Warrantholder. If Warrantholder institutes any action or proceeding to specifically enforce the provisions hereof, any person against whom such action or proceeding is brought hereby waives the claim or defense therein that Warrantholder has an adequate remedy at law, and such person shall not offer in any such action or proceeding the claim or defense that such remedy at law exists.

 

(s) Lost, Stolen, Mutilated or Destroyed Warrant . If this Warrant is lost, stolen, mutilated or destroyed, the Company may, on such terms as to indemnity or otherwise as it may reasonably impose (which shall, in the case of a mutilated Warrant, include the surrender thereof), issue a new Warrant of like denomination and tenor as this Warrant so lost, stolen, mutilated or destroyed. Any such new Warrant shall constitute an original contractual obligation

 

11  

 

of the Company, whether or not the allegedly lost, stolen, mutilated or destroyed Warrant shall be at any time enforceable by anyone.

 

(t) Language . The official language of this Warrant and of all notices and other communications between the parties hereunder shall be English.

 

(u) Legends . To the extent required by applicable laws, this Warrant and the Common Shares issuable hereunder (and the securities issuable, directly or indirectly, upon conversion of such Common Shares, if any) may be imprinted with a restricted securities legend in substantially the following form:

 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE US SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), ANY US STATE SECURITIES LAWS, OR UNDER THE SECURITIES LAWS OF ANY OTHER JURISDICTION, AND MAY NOT BE SOLD, PLEDGED OR OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION THEREOF UNDER SUCH ACT AND LAWS, OR PURSUANT TO RULE 144 AND/OR OTHER EXEMPTION FROM SUCH REGISTRATION REQUIREMENTS.

 

[Remainder of Page Intentionally Left Blank]

 

12  

 

IN WITNESS WHEREOF, the parties hereto have caused this Warrant Agreement to be executed by its officers thereunto duly authorized as of the Effective Date.

 

COMPANY: AURIS MEDICAL HOLDING AG
       
       
  By:     
  Name:     
  Title:     
       
       
WARRANTHOLDER:   HERCULES CAPITAL, INC.
       
       
  By:     
  Name: Ben Bang  
  Title: Associate General Counsel  

13  

 

EXHIBIT I

 

NOTICE OF EXERCISE

 

To: [____________________________]

 

(1) The undersigned Warrantholder hereby irrevocably elects to purchase [_______] Common Shares of a par value of CHF 0.40 each of [_________________], pursuant to the terms of the Agreement dated the [___] day of [______, _____] between Auris Medical Holding AG and the Warrantholder (the "Agreement") and by reference to article [_______] of the Charter, and tenders herewith payment of the aggregate Purchase Price of CHF [_______] in full, together with all applicable taxes and charges, if any.

 

(2) Please issue said Common Shares in the name of the undersigned or in such other name as is specified below and conform in writing to the undersigned such issuance.

 

(3) Capitalized terms used but not defined herein shall have the meaning ascribed to such term in the Agreement.

 

     
  (Name)  
     
      
  (Address)  
     
     
WARRANTHOLDER: HERCULES CAPITAL, INC.
       
  By:     
  Name:     
  Title:     

14  

 

EXHIBIT II

 

1. ACKNOWLEDGMENT OF EXERCISE

 

The undersigned [____________________________________], hereby acknowledge receipt of the "Notice of Exercise" from Hercules Capital, Inc. to purchase [____] Common Shares of [_________________], pursuant to the terms of the Agreement, and further acknowledges that [______] shares remain subject to purchase under the terms of the Agreement.

 

COMPANY: [_________________]
   
   
  By:     
       
  Title:     
       
  Date:     

15  

 

EXHIBIT III

 

TRANSFER NOTICE

 

(To transfer or assign the foregoing Agreement execute this form and supply required information. Do not use this form to purchase shares.)

 

FOR VALUE RECEIVED, the foregoing Agreement and all rights evidenced thereby are hereby transferred and assigned to

 

    
(Please Print)  
     
whose address is    
     
    
   
   
  Dated:     
       
       

 

  Holder's Signature:     
       
       

 

  Holder's Address:     
       
       
        
Signature Guaranteed:         

 

 

NOTE: The signature to this Transfer Notice must correspond with the name as it appears on the face of the Agreement, without alteration or enlargement or any change whatever. Officers of corporations and those acting in a fiduciary or other representative capacity should file proper evidence of authority to assign the foregoing Agreement.

 

16  

 

 

 

Exhibit 10.3

 

Execution version

 

 

Share Pledge AGREEMENT

 

  

 

July 19, 2016

 

 

between

 

 

Auris Medical Holding AG

as Pledgor

 

 

and

 

 

Hercules Capital, Inc.,

as Agent and Pledgee

 

 

and

 

 

the other Lenders

 

 

 

regarding the shares of

Auris Medical AG

 

 

Share Pledge Agreement  

Contents

 

Clause Page
1. Interpretation and definitions 1
2. Role of the Agent 3
3. Pledge of Shares 3
4. Continuing and additional security 3
5. Variation of Secured Obligations 4
6. Representations and warranties 4
7. Covenants of the Pledgor 5
8. Voting rights 7
9. Dividends and other pecuniary rights 7
10. Realization 7
11. Redelivery of pledged shares and proxy 8
12. Assignments and transfers 8
13. Expenses and indemnification 9
14. Amendment and waiver 9
15. Notices 9
16. Language 9
17. Severance 9
18. Entire agreement 10
19. Governing law and jurisdiction 10
     
Schedules Page
Schedule 1 Proxy 12

 

Share Pledge Agreement 1 /12

THIS AGREEMENT is dated July 19, 2016

 

PARTIES

 

(1) Auris Medical Holding AG , Bahnhofstrasse 21, 6300 Zug, Switzerland (the " Pledgor ")

 

(2) Hercules Capital, Inc. , 400 Hamilton Avenue, Suite 310, Palo Alto, CA 94301, USA (the " Agent ")

 

(3) the other Lenders, represented for all purposes hereof by the Agent as direct representative ( direkter Stellvertreter ) (together with the Agent, the " Pledgees ")

 

BACKGROUND

 

(A) Auris Medical Holding AG (as Borrower), Hercules Capital, Inc. (as Lender and Agent) and certain other lenders are parties to that certain loan and security agreement dated on or about the date hereof pursuant to which the Lender (as defined therein) has agreed to make available certain term loan advances to the Borrower (the " Loan and Security Agreement ").

 

(B) The Lender has agreed to make available to the Borrower such term loan advances conditional upon, inter alia , the Pledgor pledging all Shares (as defined below) to the Pledgee as security for the due and punctual satisfaction of the Secured Obligations (as defined in the Loan and Security Agreement).

 

(C) The Pledgor is willing to grant a pledge over the Shares to the Pledgees according to the terms of this Agreement, and the Pledgees are willing to accept such pledge.

 

AGREED TERMS

 

1. Interpretation and definitions

 

1.1 In this Agreement the following expressions shall have the following meanings:

 

" Agent " means the Agent as identified in the parties list above and its permitted successors, as the case may be;

 

" Agreement " means this agreement (including its schedules) and all the terms contained in it;

 

" Company " means Auris Medical AG, a Swiss stock corporation ( Aktiengesellschaft ) with its registered seat in Basel, with a share capital ( Aktienkapital ) of CHF 2'500'000 divided into 2’500 shares ( Aktien ) of a nominal value of CHF 1’000 each;

 

" DEBA " means the Swiss Federal Debt Enforcement and Bankruptcy Act ( Schuldbetreibungs- und Konkursgesetz ) of April 11, 1889;

 

" Dividend Payments " has the meaning given to it in clause 9.1;

 

" Effective Date " means the date first set forth above;

 

" Loan and Security Agreement " has the meaning given to it in Background (A);

 

" Party " means a party to this Agreement;

 

 

Share Pledge Agreement 2 /12

" Pledge " means the pledge agreed and granted in clause 3.1 and, if applicable, as extended as agreed in this Agreement;

 

" Pledgees " means the pledgees as identified in the parties list above and their permitted successors, as the case may be (including, for the avoidance of doubt, the Agent);

 

" Pledgor " means the pledgor as identified in the parties list above and its permitted successors, as the case may be;

 

" Shares " means all of the issued shares ( Aktien ) in the Company at any given time.

 

1.2 Terms not defined in this Agreement shall have the meaning given to them in the Loan and Security Agreement.

 

1.3 The table of contents and headings and sub-headings of this Agreement are for convenience only and shall not affect the construction of this Agreement.

 

1.4 The words "other", "include", "including" and "in particular" do not connote limitation in any way.

 

1.5 Unless the context otherwise requires, words denoting the singular shall include the plural and vice versa and references to any gender shall include all other genders.

 

1.6 References to any person (which for the purposes of this Agreement shall include bodies corporate, unincorporated associations, partnerships, trusts, governments, governmental agencies and departments, statutory bodies or other entities, in each case whether or not having a separate legal personality) shall include the person's successors.

 

1.7 References to recitals, schedules, clauses and sub-clauses are references to recitals, schedules, clauses and sub-clauses of this Agreement (unless otherwise specified) and references within a schedule to paragraphs are to paragraphs of that schedule (unless otherwise specified).

 

1.8 References in this Agreement to any statute, ordinance, statutory provision, regulation, directive or other legislation include a reference to that legislation as amended or replaced from time to time (whether before or after the Effective Date) and include any order, regulation, instrument or other subordinate legislation made under the relevant legislation, and references in this Agreement to any agreement or document include a reference to that agreement or document (including its schedules) as varied, amended, supplemented or replaced from time to time (whether before or after the Effective Date).

 

1.9 References to any Swiss legal term for any action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official or any legal concept, state of affairs or thing shall in respect of any jurisdiction other than Switzerland be deemed to refer to and include that action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official, legal concept, state of affairs or thing which most nearly approximates in that jurisdiction to the Swiss legal term.

 

1.10 Where a German term has been inserted after an English term in italics, the German term alone shall be authoritative for the purpose of interpreting such English term, without regard to any other interpretation of the English term.

 

 

Share Pledge Agreement 3 /12

1.11 This Agreement is drafted in English for convenience purposes only, and the fact that the English language is used herein shall not be a reason to refer to laws, doctrine or case law of any English-speaking jurisdiction in the interpretation of this Agreement. Rather, this Agreement, and the security created hereunder, shall exclusively be interpreted by reference to Swiss laws, doctrine and case law.

 

1.12 Any reference to "writing" or "written" includes faxes and any legible reproduction of words delivered in permanent and tangible form, and PDF files transmitted by e-mail (but not plain e-mail).

 

2. Role of the Agent

 

2.1 Any reference in this Agreement to the Agent shall, unless expressly otherwise provided, be a reference to the Agent acting for itself and (as direct representative ( direkter Stellvertreter )) in the name, on behalf and for the benefit of the other Pledgees.

 

2.2 Any actions, rights, powers and discretion of the Pledgees under this Agreement shall be exclusively made and exercised by the Agent.

 

2.3 Any documents, assets and notices to be delivered and given, respectively, by the Pledgor to the Pledgees under this Agreement shall be exclusively delivered and given, respectively, to the Agent.

 

3. Pledge of Shares

 

3.1 For the purpose of securing the Secured Obligations, the Pledgor hereby undertakes to pledge and hereby pledges ( verpfändet ) to the Pledgees the Shares and (i) all ancillary present and future rights and claims pertaining thereto, including claims for dividends, other benefits payable to the Pledgor in its capacity as shareholder or profit distributions, capital repayments, subscription rights, pre-emptive rights and claims for liquidation proceeds, and (ii) all additional shares in the Company from time to time acquired by the Pledgor in any manner, and the Pledgees hereby accept such right of pledge.

 

3.2 If the Shares are changed, subdivided, consolidated, exchanged or converted through a merger or otherwise, the pledge created under this Agreement shall also extend to such shares as changed, subdivided, consolidated, exchanged or converted and the Pledgor undertakes to promptly undertake all acts to have the pledge right created hereby perfected.

 

4. Continuing and additional security

 

4.1 The Pledge shall remain in force, and shall not be satisfied by any intermediate payment or intermediate satisfaction of any part of the Secured Obligations or by any intermediate settlement of accounts, until all of the Secured Obligations have been unconditionally and irrevocably paid in full (other than inchoate indemnity obligations) and no further Secured Obligations are capable of arising.

 

4.2 If, in the course of bankruptcy proceedings, any payment remitted in order to pay the Secured Obligations, is avoided or set aside or ordered to be refunded or reduced, on the grounds of fraudulent preference or otherwise, the obligations of the Pledgor hereunder shall revive and the security interest constituted by this Agreement shall continue with respect to the Secured Obligations the payment of which was avoided, set aside or ordered to be refunded or reduced.

 

 

Share Pledge Agreement 4 /12

4.3 The Pledge shall be cumulative, and shall be in addition to, and shall not in any way be prejudiced by or dependent on any collateral or other security now or thereafter held by or for the benefit of the Pledgees as security for the Secured Obligations or any lien to which they may be entitled (whether by contract or statute). The rights of the Pledgees hereunder are in addition to and not in lieu of those provided by law. The Pledge secures the Pledgees up to the amount of the Secured Obligations from time to time outstanding.

 

4.4 To the fullest extent permitted by applicable law, the Pledgor waives any right it may have to require the Pledgees to first proceed against, or claim payment from, any person or enforce any guarantee or security granted by any person before enforcing this Agreement and/or their rights hereunder or pursuant hereto.

 

5. Variation of Secured Obligations

 

The Pledgor herewith expressly agrees that the Pledge shall (to the extent legally possible) extend from time to time to any (however fundamental) variation, increase or extension of the Secured Obligations.

 

6. Representations and warranties

 

6.1 In addition to, and without in any way limiting the representations and warranties made in the other Loan Documents, but subject to the security rights created and the obligations imposed on the Pledgor by virtue of this Agreement or any other Loan Document, the Pledgor hereby represents and warrants that on the Closing Date and, except as explicitly stated otherwise hereafter, on each Advance Date:

 

(a) it is duly incorporated and validly existing under the laws of Switzerland and has the power to carry on its business as it is now being conducted and to own its property and other assets;

 

(b) this Agreement constitutes legal, valid and binding obligations of the Pledgor enforceable in accordance with the terms and conditions set forth herein;

 

(c) the entering into, the execution and the performance of this Agreement have been duly authorized by all necessary corporate and other action and do not conflict with, and (with regard to agreements) do not constitute an event of default under, any provision of its articles of association or other constitutional documents or any provision of law, regulation, decision, decree, order of court, of an arbitration panel or of a public authority or any agreement, arrangement or other instrument to which the Pledgor is a party or by which it or any of its assets are bound or affected;

 

(d) it is the sole legal and beneficial owner of, and entitled to all rights and benefits in relation to, the Shares;

 

(e) it has not assigned, transferred, sold or otherwise disposed of, the benefit of all or any of its rights, title and interest in the Shares;

 

(f) save for Permitted Liens, the Shares are free and clear from any Liens;

 

(g) the Shares are fully pledgeable as of the date of their pledge to the Pledgees hereunder purportedly becoming effective;

 

 

Share Pledge Agreement 5 /12

(h) no demand, order or resolution for the liquidation of the Company or for the protection of the Company from its creditors has been filed or is currently pending;

 

(i) the Company is not subject to any bankruptcy proceedings or proceedings for composition or suspension of payment, and no such proceedings have been applied for;

 

(j) the Shares have been validly issued and fully paid in and no obligations to effect additional contributions of share capital exist;

 

(k) the Shares represent all of the issued share capital of the Company and the Company has not issued any equity interest other than the Shares, all subject to any additional and/or, amongst others, changed shares as referred to in clauses 3.1(ii) and 3.2, and as at the Closing Date no instruments have been issued which entitle their holders to subscribe to or request the issuance of further shares or other equity interests in the Company;

 

(l) the registered share certificate delivered according to clause 7.1(e) has been duly issued and no other share certificates have been issued by the Company, subject to any certificates representing additional and/or, amongst others, changed shares as referred to in clauses 3.1(ii) and 3.2; and

 

(m) no board or shareholders’ resolution of the Pledgor or the Company has been passed, and the Pledgor is not aware of any other circumstance, which would be reasonably likely to have a material adverse effect (in terms of value, enforceability or otherwise) on the Pledge or any other right of the Pledgees under this Agreement.

 

6.2 The representations and warranties above are made at the time(s) as set out in clause 6.1 and are repeated as of the date of each additional pledge purportedly becoming effective hereunder.

 

7. Covenants of the Pledgor

 

7.1 On the Closing Date, the Pledgor shall deliver to the Agent a copy of each:

 

(a) a certified copy of the current articles of association ( Statuten ) of the Company;

 

(b) the minutes of a resolution passed by the board of directors of the Pledgor approving the entering into, execution and performance by the Pledgor of this Agreement;

 

(c) the minutes of a resolution of the board of directors of the Company (i) approving the granting of the Pledge, and (ii) confirming that any acquirer of the Shares in connection with the enforcement of the Pledge shall be acknowledged as a new shareholder of the Company and shall be registered in the share register of the Company;

 

(d) the revised articles of association of the Company providing for free transferability of the Shares, the public deed resolving their enactment and the application to the commercial register for their registration;

 

(e) the original share certificate evidencing all Shares duly endorsed in blank;

 

 

Share Pledge Agreement 6 /12

(f) a copy of the share register ( Aktienbuch ) of the Company signed by one director of the Company, evidencing that (i) the Pledgor is the registered shareholder of the Shares, and (ii) the Shares are pledged to the Pledgees; and

 

(g) a proxy executed by the Pledgor ( Schedule 1), which shall be renewed from time to time upon the Agent's reasonable request.

 

7.2 The Pledgor undertakes and covenants for as long as any of the Secured Obligations remains unpaid or is capable of arising as follows:

 

(a) unless expressly otherwise permitted by the Loan and Security Agreement, not to enter into any legal instrument relating to, or grant or permit to be created or to subsist any Lien, other than a Permitted Lien, over, or sell, assign, transfer or otherwise dispose of, the Shares or take or permit any other action or omission that could impair or jeopardize any rights of the Pledgees under this Agreement or could impair or jeopardize the enforcement of the security interest under this Agreement or the value of the Shares;

 

(b) except with the Agent's prior written consent, which shall not be unreasonably withheld, not to vote in favor of any shareholders' resolution of the Company whereby:

 

(i) the articles of association of the Company (as amended pursuant to clause ‎7.1(c)) would be amended in any manner which would be reasonably likely to have a Material Adverse Effect;

 

(ii) shares or other equity, or the granting of rights to purchase or otherwise acquire any rights in or to shares or other equity interest in the Company would be created or issued, except for the issuance of additional shares or other equity interest in the Company in a capital increase by means of a cash contribution ( Barliberierung ) to the Pledgor, who shall immediately perfect the pledge to the Pledgees over such shares pursuant to clause ‎7.2(c);

 

(iii) the Company's share capital would be reduced;

 

(iv) the Company would be dissolved (with or without liquidation);

 

(v) the Company would be merged with any other entity or split;

 

(vi) the Company's corporate domicile would be relocated abroad; or

 

(vii) any of the Shares would be modified;

 

(c) promptly upon becoming the owner (directly or indirectly) of any additional shares or other equity interest in the Company, to do everything necessary and useful to perfect the pledge granted to the Pledgees over such shares or other equity interest pursuant to clause 3.1 (respectively, in case of indirect ownership, to procure such pledging) and to promptly deliver to the Agent the respective share certificates and the respectively updated share register of the Company;

 

(d) to procure that the Company does not dispose of or allow the creation or continuance of any Lien over any of its Intellectual Property; and

 

 

Share Pledge Agreement 7 /12

(e) to promptly do all things and execute all documents that are reasonably requested by the Agent from time to time for the purpose of the exercise of the Pledgees' rights hereunder or securing or perfecting the security interest under this Agreement.

 

8. Voting rights

 

8.1 Until such time when an Event of Default has occurred and is continuing, the Pledgor shall have the right to exercise any and all membership rights pertaining to the Shares, in particular the right to vote in the shareholders’ meeting of the Company.

 

8.2 Upon the occurrence of an Event of Default and during the continuance thereof, the Agent shall forthwith be entitled to exercise solely and exclusively all voting and consensual powers pertaining to the Shares and may exercise such powers in its sole discretion.

 

8.3 The Agent may only use the proxy ( Schedule 1) upon the occurrence of an Event of Default and during the continuance thereof.

 

9. Dividends and other pecuniary rights

 

9.1 Until such time when an Event of Default has occurred and is continuing, and subject to the terms and conditions of this Agreement, the Pledgor shall be entitled (i) to receive all monies and other assets payable in respect of the Shares (such as dividends, profit distributions or capital repayments in relation to the Shares) (the “ Dividend Payments ”) and (ii) to exercise all pecuniary rights in connection with the Shares.

 

9.2 Upon the occurrence of an Event of Default and during the continuance thereof, the Agent shall forthwith be entitled (i) to receive all Dividend Payments and any other benefits in relation to the Shares, and (ii) to exercise all pecuniary rights in connection with the Shares. The Pledgor shall, if such payments are made to it rather than to the Agent, promptly transfer the same to the Agent in the identical form as received and, until such transfer occurs, shall hold the respective funds in trust for the Pledgees and segregated from other funds of the Pledgor.

 

10. Realization

 

10.1 Upon the occurrence of an Event of Default and during the continuance thereof, the Agent shall without further notification at any time be, at its sole discretion, entitled, but not obligated:

 

(a) to realize the Shares in full or in part through

 

(i) a bona fide private sale ( private Verwertung ) at fair market value or acquisition of the Shares for its own account ( Selbsteintritt ) at fair market value, or

 

(ii) a public auction or public offering;

 

in either case without having to initiate proceedings under, and without regard to the formalities provided in, the DEBA, and to transfer the Shares to any third party; or

 

(b) to enforce the Pledge by means of official enforcement proceedings (including enforcement proceedings in respect of the Shares ( Betreibung auf Faustpfandverwertung )) in accordance with the DEBA;

 

 

Share Pledge Agreement 8 /12

in each case applying the resulting proceeds to the discharge of the Secured Obligations in accordance with the terms of the Loan and Security Agreement. The Agent shall promptly account for the proceeds of any sale, auction or offering.

 

10.2 Notwithstanding clause 10.1 above and notwithstanding article 41 DEBA, the Agent is at liberty to enforce any Secured Obligations prior to the enforcement of the Pledge and to commence or pursue the regular debt enforcement proceedings against the Pledgor or any other debtor of the Secured Obligations without having first to realize any of the Shares or other pledged assets or to institute statutory proceedings for the realization thereof, without foregoing any of the Pledgees' rights hereunder.

 

10.3 For the avoidance of doubt, if the Pledge is enforced or if the Pledgor or any other debtor has discharged any of the Secured Obligations, no legal subrogation of claims shall occur and no related rights of the Pledgees shall pass to the Pledgor or any other debtor by subrogation or otherwise for as long as any of the Secured Obligations remains unpaid or is capable of arising.

 

10.4 If the proceeds resulting from enforcement actions pursuant to this clause 10 exceed the Secured Obligations, upon unconditional and irrevocable satisfaction of all Secured Obligations (except for inchoate indemnity obligations) and no further Secured Obligations being capable of arising, the Agent shall promptly account for and remit the excess amount to the Pledgor.

 

11. Redelivery of pledged shares and proxy

 

11.1 Upon expiry of the Pledge pursuant to clause 4.1, the Agent herewith undertakes to, at the Pledgor's cost, promptly release the Shares and redeliver all certificates evidencing the Shares to the Pledgor or to any other person designated by the Pledgor, free and clear of any Lien created by the Pledgees, and to do any and all acts reasonably required for such release and redelivery.

 

11.2 Clause 11.1 shall apply mutatis mutandis to all further assets (if any) having become subject to the Pledge in accordance with this Agreement and to the proxy ( Schedule 1).

 

11.3 For the sake of clarity it is expressly agreed that clauses 4.2 and 12.3 shall survive the release as per this clause 11 and – except as explicitly agreed otherwise – the termination of this Agreement for as long as respective claims are capable of arising, provided, however, that the occurrence of any claims under clause 12.3 after such release or termination shall not result in a revival of the security interest constituted by this Agreement.

 

12. Assignments and transfers

 

12.1 The Pledgees shall have the right to transfer or assign all or part of their rights and/or obligations under this Agreement (including, but not limited to, a transfer of the entire contractual relationship of this Agreement ( Vertragsübernahme durch einen Dritten )) to any party to whom the Pledgees assign their rights or transfer or syndicate, or grant sub-participations or other interests in, their rights and obligations as permitted under the terms of the Loan and Security Agreement. The Pledgor hereby explicitly agrees to such transfer or assignment and undertakes, upon first request of the Pledgees, to take all measures and do all acts necessary or useful in relation to such transfer or assignment.

 

12.2 If a replacement or successor agent of the Agent is appointed in accordance with the terms of the Loan and Security Agreement, the Agent shall automatically be replaced by that

 

 

Share Pledge Agreement 9 /12

replacement or successor agent as the respective Party to this Agreement, such replacement being valid and enforceable for and against the Pledgor upon notification to the Pledgor of such replacement or succession.

 

12.3 The rights and obligations of the Pledgor under this Agreement may not be assigned or transferred without the prior written consent of the Agent.

 

13. Expenses and indemnification

 

13.1 The Pledgor's obligation to reimburse the Pledgees for costs, expenses, fees and damages shall be governed by section 6.3 of the Loan and Security Agreement.

 

13.2 Unless caused (by action or omission) intentionally or grossly negligent, the Pledgees shall not be liable for any losses of the Pledgor or of the Company arising in connection with the exercise or purported exercise of any of their rights, powers and discretion under this Agreement.

 

14. Amendment and waiver

 

14.1 Any amendment of this Agreement, including any amendment of this clause 14.1, must be in writing in order to be valid.

 

14.2 A waiver of any right under this Agreement is only effective if it is in writing and it applies only to the Party to which the waiver is addressed and the circumstances for which it is given.

 

14.3 The failure or delay by a Party in exercising any right or remedy under or in connection with this Agreement will not constitute a waiver of such right or remedy.

 

14.4 No waiver of any provision of this Agreement or of any right or remedy in connection with this Agreement shall constitute a continuing waiver or a waiver relating to a subsequent breach of such provision, right or remedy under this Agreement.

 

15. Notices

 

15.1 Any notice to be given under this Agreement shall be given pursuant to section 11.2 of the Loan and Security Agreement.

 

16. Language

 

16.1 All notices or formal communications in connection with this Agreement shall be in English.

 

17. Severance

 

17.1 The invalidity of individual parts of this Agreement shall have no impact on the validity of the Agreement as a whole. The Parties agree that if any provision or part of a provision of this Agreement is deemed invalid, inoperative or otherwise not enforceable, the Agreement as a whole shall remain valid and the invalid provision or part of a provision shall be replaced by a provision which the Parties would have agreed on in good faith if they had been aware of the invalidity.

 

 

Share Pledge Agreement 10 /12

18. Entire agreement

 

18.1 In this clause 18, references to this Agreement include all other written agreements and arrangements between the Parties which are expressed to be supplemental to this Agreement or which this Agreement expressly preserves or requires to be executed.

 

18.2 This Agreement constitutes the whole and only understanding between the Parties in relation to its subject matter. All previous drafts, agreements, understandings, undertakings, representations, warranties, promises and arrangements of any nature whatsoever between the Parties with any bearing on the subject matter of this Agreement are superseded and extinguished to the extent that they have such a bearing and each of the Parties acknowledges to the other that it is not entering into this Agreement in consequence of or in reliance on anything it is the purpose of this clause to exclude.

 

18.3 The schedules to this Agreement are an integral part of this Agreement.

 

19. Governing law and jurisdiction

 

19.1 This Agreement and the Pledge (including matters as to the perfection of the Pledge as a right in rem , in particular the transfer and possession of any certificates representing the Shares) shall in all respects be governed by and construed in accordance with Swiss substantive law.

 

19.2 The Parties submit to the exclusive jurisdiction of the competent court of Zurich 1 for all disputes arising out of or in connection with this Agreement.

 

[Remainder of page left blank intentionally; signature page follows]

 

 

Share Pledge Agreement 11 /12

Pledgor Auris Medical Holding AG  
     
      
  Name:
Title:
 
     
      
  Name:
Title:
 
     
Agent
acting for itself and as direct representative ( direkter Stellvertreter ) of the other Pledgees
Hercules Capital, Inc.  
     
      
  Name:
Title:
 

 

Without becoming a party to this Agreement, the Company hereby undertakes to comply with the covenant made in clause 7.2(d) as if it were its own covenant.

 

Company Auris Medical AG  
     
      
  Name:
Title:
 
     
      
  Name:
Title:
 

 

Share Pledge Agreement 12 /12

Schedule 1
Proxy

 

AUTHORITY AND INSTRUCTION TO VOTE (PROXY)

 

Auris Medical Holding AG
Bahnhofstrasse 21
6300 Zug
Switzerland
( Shareholder )

 

as shareholder of
Auris Medical AG ,
a Swiss stock corporation domiciled in Basel, Switzerland,
( Company )

 

hereby grants an irrevocable power of attorney to

 

Hercules Capital, Inc.
400 Hamilton Avenue
Suite 310, Palo Alto
CA 94301
USA
( Attorney )

 

with the right of substitution, to fully represent the Shareholder at any and all shareholders' meetings of the Company and to exercise his voting rights for any business which may properly come before such shareholders' meetings.

 

The Shareholder further expressly agrees with the form, the date and the place of any shareholders' meeting and with the manner in which it has been called (whether or not such meeting will be constituted as a plenary meeting within the meaning of art. 701 of the Swiss Code of Obligations).

 

The present authority and instruction is governed by the laws of the State of California, USA.

 

Place and date: _______________________

 

Auris Medical Holding AG:

 

 

       
by:   by:  

 

 

 

Exhibit 10.4

 

Execution version

 

 

CLAIMS Security ASSIGNMENT AGREEMENT

 

 

 

 

July 19, 2016

 

 

between

 

 

Auris Medical Holding AG

as Assignor

 

 

and

 

 

Hercules Capital, Inc.,

as Agent and Assignee

 

 

 

regarding the security assignment of
intercompany receivables

 

 

Claims Security Assignment Agreement

 

Contents

 

Clause Page
1. Interpretation and definitions 1
2. Role of the Agent 3
3. Assignment 3
4. Continuing and additional security 3
5. Variation of Secured Obligations 4
6. Representations and warranties 4
7. Covenants of Assignor 5
8. Administration of Account Receivables 5
9. Realization 5
10. Waiver of secrecy rights 6
11. Audit 7
12. Reassignment of Account Receivables 7
13. Assignments and transfers 7
14. Expenses and indemnification 7
15. Amendment and waiver 8
16. Notices 8
17. Language 8
18. Severance 8
19. Entire agreement 8
20. Governing law and jurisdiction 9
     
Schedules Page
Schedule 1 Notification Letter (Upon Event of Default) 11

 

Claims Security Assignment Agreement 1 /12

THIS AGREEMENT is dated July 19, 2016

 

PARTIES

 

(1) Auris Medical Holding AG , Bahnhofstrasse 21, 6300 Zug, Switzerland (the " Assignor ");

 

(2) Hercules Capital, Inc. , 400 Hamilton Avenue, Suite 310, Palo Alto, CA 94301, USA (the " Agent ")

 

BACKGROUND

 

(A) Auris Medical Holding AG (as Borrower), Hercules Capital, Inc. (as Lender and Agent) and certain other lenders are parties to that certain loan and security agreement dated on or about the date hereof pursuant to which the Lender (as defined therein) has agreed to make available certain term loan advances to the Borrower (the " Loan and Security Agreement ").

 

(B) The Lender has agreed to make available to the Borrower such term loan advances conditional upon, inter alia, the Assignor assigning the Account Receivables (as defined below) to the Agent as security for the due and punctual satisfaction of the Secured Obligations (as defined in the Loan and Security Agreement).

 

(C) The Assignor is willing to assign for security purposes the Account Receivables to the Agent according to the terms of this Agreement, and the Agent is willing to accept such assignment.

 

AGREED TERMS

 

1. Interpretation and definitions

 

1.1 In this Agreement the following expressions shall have the following meanings:

 

" Account Receivables " means any and all present and future, actual and contingent assignable claims of the Assignor against Auris Medical AG, Switzerland, Otolanum AG, Switzerland, and any other Subsidiary domiciled in Switzerland (whether now existing or formed or redomiciled in the future), in each case including, to the extent possible, all accessory rights and rights which are or hereafter will be dependent upon any such claims, such as rights arising out of (bank) guarantees connected or hereafter to be connected with any such claim;

 

" Agent " means the Agent as identified in the parties list above and its permitted successors, as the case may be;

 

" Agreement " means this agreement (including its schedules) and all the terms contained in it;

 

" Assignment " means the security interest created by this Agreement pursuant to clause 2.

 

" Assignor " means the assignor as identified in the parties list above and its permitted successors, as the case may be;

 

" Business Day " means a day on which banks are open for business in Zug, Switzerland;

 

" DEBA " means the Swiss Federal Debt Enforcement and Bankruptcy Act ( Schuldbetreibungs- und Konkursgesetz ) of April 11, 1889;

 

 

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" Effective Date " means the date first set forth above;

 

" Loan and Security Agreement " has the meaning given to it in Background (A);

 

" Party " means a party to this Agreement;

 

1.2 Terms not defined in this Agreement shall have the meaning given to them in the Loan and Security Agreement.

 

1.3 The table of contents and headings and sub-headings of this Agreement are for convenience only and shall not affect the construction of this Agreement.

 

1.4 The words "other", "include", "including" and "in particular" do not connote limitation in any way.

 

1.5 Unless the context otherwise requires, words denoting the singular shall include the plural and vice versa and references to any gender shall include all other genders.

 

1.6 References to any person (which for the purposes of this Agreement shall include bodies corporate, unincorporated associations, partnerships, trusts, governments, governmental agencies and departments, statutory bodies or other entities, in each case whether or not having a separate legal personality) shall include the person's successors.

 

1.7 References to recitals, schedules, clauses and sub-clauses are references to recitals, schedules, clauses and sub-clauses of this Agreement (unless otherwise specified) and references within a schedule to paragraphs are to paragraphs of that schedule (unless otherwise specified).

 

1.8 References in this Agreement to any statute, ordinance, statutory provision, regulation, directive or other legislation include a reference to that legislation as amended or replaced from time to time (whether before or after the Effective Date) and include any order, regulation, instrument or other subordinate legislation made under the relevant legislation, and references in this Agreement to any agreement or document include a reference to that agreement or document (including its schedules) as varied, amended, supplemented or replaced from time to time (whether before or after the Effective Date).

 

1.9 References to any Swiss legal term for any action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official or any legal concept, state of affairs or thing shall in respect of any jurisdiction other than Switzerland be deemed to refer to and include that action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official, legal concept, state of affairs or thing which most nearly approximates in that jurisdiction to the Swiss legal term.

 

1.10 Where a German term has been inserted after an English term in italics, the German term alone shall be authoritative for the purpose of interpreting such English term, without regard to any other interpretation of the English term.

 

1.11 This Agreement is drafted in English for convenience purposes only, and the fact that the English language is used herein shall not be a reason to refer to laws, doctrine or case law of any English-speaking jurisdiction in the interpretation of this Agreement. Rather, this Agreement, and the security created hereunder, shall exclusively be interpreted by reference to Swiss laws, doctrine and case law.

 

 

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1.12 Any reference to "writing" or "written" includes faxes and any legible reproduction of words delivered in permanent and tangible form, and PDF files transmitted by e-mail (but not plain e-mail).

 

2. Role of the Agent

 

2.1 Any reference in this Agreement to the Agent shall, unless expressly otherwise provided, be a reference to the Agent acting for its own benefit and for the benefit of the Lender.

 

3. Assignment

 

3.1 For the purpose of securing the Secured Obligations, the Assignor hereby undertakes to assign and hereby assigns by way of security assignment ( Sicherungszession ) any and all Account Receivables to the Agent, and the Agent hereby accepts such assignment. Where an Account Receivable does not yet exist on the Effective Date, its assignment shall become effective with the arising of such future Account Receivable ( Abtetung einer künftigen Forderung ).

 

3.2 For the avoidance of doubt and notwithstanding any provision of this Agreement to the contrary, the Parties acknowledge and agree that each assignment made under this Agreement is immediate (with effect as of the Effective Date for the initial assignment) and unconditional.

 

4. Continuing and additional security

 

4.1 The Assignment shall remain in force, and shall not be satisfied by any intermediate payment or intermediate satisfaction of any part of the Secured Obligations or by any intermediate settlement of accounts, until all of the Secured Obligations have been unconditionally and irrevocably paid in full (other than inchoate indemnity obligations) and no further Secured Obligations are capable of arising.

 

4.2 If any payment remitted in order to pay the Secured Obligations, in the course of bankruptcy proceedings, on the grounds of fraudulent preference or otherwise, is deemed capable of being avoided or set aside or ordered to be refunded or reduced, the obligations of the Assignor hereunder shall revive and the security interest constituted by this Agreement shall continue with respect to the Secured Obligations to the extent any payment thereof is deemed capable of being avoided, set aside or ordered to be refunded or reduced.

 

4.3 The Assignment shall be cumulative, and shall be in addition to, and shall not in any way be prejudiced by or dependent on any collateral or other security now or thereafter held by or for the benefit of the Agent as security for the Secured Obligations or any lien to which it may be entitled (whether by contract or statute). The rights of the Agent hereunder are in addition to and not in lieu of those provided by law. The Assignment secures the Agent up to the amount of the Secured Obligations from time to time outstanding.

 

4.4 To the fullest extent permitted by applicable law, the Assignor waives any right it may have to require the Agent to first proceed against, or claim payment from, any person or enforce any guarantee or security granted by any person before enforcing this Agreement and/or its rights hereunder or pursuant hereto.

 

 

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5. Variation of Secured Obligations

 

5.1 The Assignor herewith expressly agrees that the Assignment shall (to the extent legally possible) extend from time to time to any (however fundamental) variation, increase or extension of the Secured Obligations.

 

6. Representations and warranties

 

6.1 In addition to, and without in any way limiting the representations and warranties made in the other Loan Documents, but subject to the security rights created and the obligations imposed on the Assignor by virtue of this Agreement or any other Loan Document, the Assignor hereby represents and warrants that on the Effective Date and on each Advance Date:

 

(a) it is duly incorporated and validly existing under the laws of Switzerland and has the power to carry on its business as it is now being conducted and to own its property and other assets;

 

(b) this Agreement constitutes legal, valid and binding obligations of the Assignor enforceable in accordance with the terms and conditions set forth herein;

 

(c) the entering into, the execution and the performance of this Agreement have been duly authorized by all necessary corporate and other action and do not conflict with, and (with regard to agreements) do not constitute an event of default under, any provision of its articles of association or other constitutional documents or any provision of law, regulation, decision, decree, order of court, of an arbitration panel or of a public authority or any agreement, arrangement or other instrument to which the Assignor is a party or by which it or any of its assets are bound or affected;

 

(d) it is the sole creditor and beneficiary of, and entitled to all rights and benefits in relation to, the Account Receivables, except for defenses of law or of fact ( Einreden und Einwendungen ) which its debtors may have, and the absence of which as of the Effective Date it hereby confirms;

 

(e) it has not assigned, transferred, sold or otherwise disposed of, the benefit of all or any of its rights, title and interest in the Account Receivables;

 

(f) save for Permitted Liens, the Account Receivables are free and clear from any Liens;

 

(g) no claims or proceedings are pending or threatened in connection with the Account Receivables; and

 

(h) the Account Receivables are fully assignable as of the date of their assignment to the Agent hereunder purportedly becoming effective.

 

6.2 The representations and warranties above are made at the time(s) as set out in clause 6.1 and are repeated as of the date of each assignment of Account Receivables purportedly becoming effective hereunder.

 

 

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7. Covenants of Assignor

 

7.1 On the Closing Date, the Assignor shall deliver to the Agent a copy of each:

 

(a) the minutes of a resolution passed by the board of directors of the Assignor approving the entering into, execution and performance by the Assignor of this Agreement; and

 

(b) a list of all Account Receivables outstanding as at the end of the last fiscal quarter preceding the Effective Date or as of a more recent date as the Assignor deems fit, setting forth the exact amounts owed to the Assignor.

 

7.2 The Assignor undertakes and covenants for as long as any of the Secured Obligations remains unpaid or is capable of arising as follows:

 

(a) unless expressly otherwise permitted by the Loan and Security Agreement, not to enter into any legal instrument relating to, or grant or permit to be created or to subsist any Lien over, other than a Permitted Lien, or dispose of, or waive, or assign any of the Account Receivables or take or permit any other action or omission that could impair or jeopardize any rights of the Agent under this Agreement or could impair or jeopardize the enforcement of the security interest under this Agreement or the value of the Account Receivables; and

 

(b) to promptly do all things and execute all documents that are reasonably requested by the Agent from time to time for the purpose of the exercise of the Agent's rights hereunder or securing or perfecting the security interest under this Agreement.

 

8. Administration of Account Receivables

 

8.1 The Agent is exclusively entitled to collect, terminate and administer the Account Receivables.

 

8.2 The Agent, however, hereby authorizes the Assignor to collect, terminate and administer the Account Receivables in the ordinary course of its business for as long as no Event of Default has occurred and is continuing. After the occurrence of an Event of Default and during the continuance thereof, the Assignor shall not, without the prior written consent of the Agent, dispose of or collect any Account Receivables.

 

8.3 Notwithstanding clause 8.2 (and any other provision of this Agreement), the Parties agree that the security interest contemplated by this Agreement shall become effective as of the Effective Date.

 

9. Realization

 

9.1 Upon the occurrence of an Event of Default and during the continuance thereof, the Assignor shall, upon request of the Agent, execute all documents and do all other things that the Agent may reasonably require to facilitate the realization of the Account Receivables.

 

9.2 Upon the occurrence of an Event of Default and during the continuance thereof, promptly upon being requested by the Agent to do so, the Assignor shall send (with a copy to the Agent) a notice to be established in accordance with Schedule 1 (or with such other form as the Agent may deem appropriate) to the debtors of the Account Receivables. If following an Event of Default any order is made, or any transaction is entered into, which may result in Account Receivables

 

 

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being owed by a new debtor, which was not covered by a notice given pursuant to this clause 9.2, the Assignor shall immediately send a notice (with a copy to the Agent) to such new debtor in accordance with Schedule 1 (or with such other form as the Agent may deem appropriate). However, nothing in this Agreement shall preclude the Agent from sending at any time on or after the Effective Date any assignment notice directly to any debtor of Account Receivables upon the occurrence of an Event of Default and during the continuance thereof or if its otherwise necessary to protect the security interest under this Agreement.

 

9.3 Upon the occurrence of an Event of Default and during the continuance thereof, the Agent shall without further notification at any time be, at its sole discretion, entitled, but not obligated:

 

(a) without prejudice to the generality of clause 8.1, to collect the Account Receivables, when due, from the relevant debtors; and/or

 

(b) to realize the Account Receivables in full or in part through a bona fide private sale ( private Verwertung ) at fair market value or acquisition of the Account Receivables for its own account ( Selbsteintritt ) at fair market value, in either case without having to initiate proceedings under, and without regard to the formalities provided in, the DEBA;

 

in each case applying the resulting proceeds to the discharge of the Secured Obligations in accordance with the terms of the Loan and Security Agreement. The Agent shall promptly account for the proceeds of any collection or sale.

 

9.4 Upon the occurrence of an Event of Default and during the continuance thereof, the Assignor shall without delay transfer any payment of the Account Receivables it receives to the account so designated by the Agent and, until such transfer occurs, shall hold the respective funds in trust for the Agent and segregated from other funds of the Assignor.

 

9.5 Notwithstanding the provisions in this clause 9, the Agent is at liberty to enforce any Secured Obligations prior to the collection or enforcement of any Account Receivables and to commence or pursue the regular debt enforcement proceedings against the Assignor or any other debtor of any of the Secured Obligations without having first to collect or enforce any Account Receivables, without foregoing any of its rights hereunder.

 

9.6 If the proceeds resulting from enforcement actions pursuant to this clause 9 exceed the Secured Obligations, upon unconditional and irrevocable satisfaction of all Secured Obligations (except for inchoate indemnity obligations) and no further Secured Obligations being capable of arising, the Agent shall promptly account for and remit the excess amount to the Assignor.

 

9.7 For the avoidance of doubt, it is expressly agreed that the Assignor shall remain liable for any Secured Obligations which are not finally settled by application of the proceeds of the realization of the Account Receivables ( keine Abtretung an Zahlungs Statt ).

 

10. Waiver of secrecy rights

 

10.1 The Assignor hereby irrevocably and unconditionally waives any secrecy rights to the extent necessary for the Agent to exercise its rights (including, but not limited to, its rights under clause 13) and obligations under this Agreement.

 

10.2 Upon occurrence of an Event of Default and during the continuance thereof, the Assignor shall, upon reasonable request of the Agent, authorize and instruct each debtor of the Account

 

 

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Receivables who is subject to a secrecy obligation to disclose any information relating to the Account Receivables to the Agent to the extent necessary for the Agent to exercise its rights and obligations under this Agreement.

 

11. Audit

 

11.1 The Agent is entitled to inspect and audit the status of the Account Receivables and to request information and production of relating documents from the Assignor pursuant to section 7.2 of the Loan and Security Agreement.

 

11.2 The Assignor undertakes to provide the Agent within five Business Days upon the occurrence of an Event of Default with a current list of all Account Receivables, setting forth the details of the Account Receivables as well as any other information the Agent may reasonably request.

 

12. Reassignment of Account Receivables

 

12.1 Upon discharge of the Secured Obligations pursuant to clause 4.1, the Agent herewith undertakes to reassign to the Assignor, at the cost of the Assignor, free and clear of any Lien created by the Agent, any and all Account Receivables and to do any and all acts reasonably required for such reassignment.

 

12.2 For the sake of clarity it is expressly agreed that clauses 4.2 and 13.2 shall survive the release as per clause 12.1 and – except as explicitly agreed otherwise – the termination of this Agreement for as long as respective claims are capable of arising, provided, however, that the occurrence of any claims under clause 13.2 after such release or termination shall not result in a revival of the security interest constituted by this Agreement.

 

13. Assignments and transfers

 

13.1 If a replacement or successor agent of the Agent is appointed in accordance with the terms of the Loan and Security Agreement, the Agent shall automatically be replaced by that replacement or successor agent as the respective Party to this Agreement, such replacement being valid and enforceable for and against the Assignor upon notification to the Assignor of such replacement or succession including evidence of the due (i) assignment and transfer of any and all rights and obligations of the Agent under this Agreement and (ii) assignment of the Account Receivables by the Agent to the successor agent.

 

13.2 The rights and obligations of the Assignor under this Agreement may not be assigned or transferred without the prior written consent of the Agent.

 

14. Expenses and indemnification

 

14.1 The Assignor's obligation to reimburse the Agent for costs, expenses, fees and damages shall be governed by section 6.3 of the Loan and Security Agreement.

 

14.2 Unless caused (by action or omission) intentionally or – if and to the extent the law permits – grossly negligently, the Agent shall not be liable for any losses of the Assignor arising in connection with the exercise or purported exercise of any of its rights, power and discretion under this Agreement.

 

 

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15. Amendment and waiver

 

15.1 Any amendment of this Agreement, including any amendment of this clause 15.1, must be in writing in order to be valid.

 

15.2 A waiver of any right under this Agreement is only effective if it is in writing and it applies only to the Party to which the waiver is addressed and the circumstances for which it is given.

 

15.3 The failure or delay by a Party in exercising any right or remedy under or in connection with this Agreement will not constitute a waiver of such right or remedy.

 

15.4 No waiver of any provision of this Agreement or of any right or remedy in connection with this Agreement shall constitute a continuing waiver or a waiver relating to a subsequent breach of such provision, right or remedy under this Agreement.

 

16. Notices

 

16.1 Any notice to be given under this Agreement shall be given pursuant to section 11.2 of the Loan and Security Agreement.

 

17. Language

 

17.1 All notices or formal communications in connection with this Agreement shall be in English.

 

18. Severance

 

18.1 The invalidity of individual parts of this Agreement shall have no impact on the validity of the Agreement as a whole. The Parties agree that if any provision or part of a provision of this Agreement is deemed invalid, inoperative or otherwise not enforceable, the Agreement as a whole shall remain valid and the invalid provision or part of a provision shall be replaced by a provision which the Parties would have agreed on in good faith if they had been aware of the invalidity.

 

19. Entire agreement

 

19.1 In this clause 19, references to this Agreement include all other written agreements and arrangements between the Parties which are expressed to be supplemental to this Agreement or which this Agreement expressly preserves or requires to be executed.

 

19.2 This Agreement constitutes the whole and only understanding between the Parties in relation to its subject matter. All previous drafts, agreements, understandings, undertakings, representations, warranties, promises and arrangements of any nature whatsoever between the Parties with any bearing on the subject matter of this Agreement are superseded and extinguished to the extent that they have such a bearing and each of the Parties acknowledges to the other that it is not entering into this Agreement in consequence of or in reliance on anything it is the purpose of this clause to exclude.

 

19.3 The schedules to this Agreement are an integral part of this Agreement.

 

 

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20. Governing law and jurisdiction

 

20.1 This Agreement and the security interest created hereunder shall in all respects, including without limitation the assignment of the Account Receivables for security purposes, be governed by and construed in accordance with Swiss substantive law.

 

20.2 The Parties submit to the exclusive jurisdiction of the competent court of Zurich 1 for all disputes arising out of or in connection with this Agreement.

 

[Remainder of page left blank intentionally; signature page follows]

 

 

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Assignor Auris Medical Holding AG  
     
      
  Name:
Title:
 
     
      
  Name:
Title:
 
     
Agent , acting for itself and for the benefit of the other Lenders Hercules Capital, Inc.  
     
      
  Name:
Title:
 

 

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Schedule 1
Notification Letter (Upon Event of Default)

 

Form: Letter by Registered Mail
   
From: The Assignor
   
To: The debtor of Account Receivables
   
Cc: The Agent

 

Notification of Assignment

 

Sir / Madam,

 

We write this letter to you both in our name and in the name of [●] (the " Agent ").

 

We inform you that we have unconditionally assigned for security purposes to the Agent all current and future, actual and contingent, principal and ancillary claims against you under, and in connection with, our current and future business relationship with you (the " Account Receivables ").

 

Any payment relating to the Account Receivables must be made by you to:

 

Bank: [●]

SIC/SWIFT: [●] 

Account holder: [●]

IBAN: [●] 

Reference: [●]

 

Please note that only payments made by you to the above account (or to such other account as indicated to you by the Agent) shall release you from any payment obligation in respect of any of the Account Receivables. Further note that this notice of assignment may only be revoked with the consent of the Agent.

 

This letter is only a notification of assignment and shall not otherwise affect our business relationship.

 

 

Yours sincerely,

 

 

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List of Accounts Receivable according to Section 7.1(b)

 

Receivables owed by Auris Medical AG:

 

- (Subordinated) loan receivable pursuant to the loan agreement dated December 31, 2014

 

- (Subordinated) loan receivable pursuant to the loan agreement dated April 1, 2016

 

- Current account credit

 

Receivables owed by Otolanum AG:

 

- (Subordinated) loan receivable pursuant to the loan agreement dated December 31, 2014

 

- (Subordinated) loan receivable pursuant to the loan agreement dated April 1, 2016

 

 

 

Exhibit 10.5

 

Execution version

  

 

Bank account CLAIMS Security ASSIGNMENT AGREEMENT

 

 

 

July 19, 2016

 

 

between

 

 

Auris Medical Holding AG

as Assignor

 

 

and

 

 

Hercules Capital, Inc.,

as Agent and Assignee

 

 

regarding the security assignment of
bank account claims

 

 

Bank Account Claims Security Assignment Agreement

  

Contents

 

Clause Page
1. Interpretation and definitions 1
2. Role of the Agent 3
3. Assignment 3
4. Continuing and additional security 3
5. Variation of Secured Obligations 4
6. Representations and warranties 4
7. Covenants of Assignor 5
8. Operation and administration of Bank Accounts 5
9. Realization 6
10. Banking secrecy 7
11. Audits and bank statements 7
12. Reassignment of Bank Account Claims 7
13. Assignments and transfers 7
14. Expenses and indemnification 7
15. Amendment and waiver 8
16. Notices 8
17. Language 8
18. Severance 8
19. Entire agreement 8
20. Governing law and jurisdiction 9
     
Schedules Page
Schedule 1 Bank Accounts 11

 

Bank Account Claims Security Assignment Agreement 1 /11

THIS AGREEMENT is dated July 19, 2016

 

PARTIES

 

(1) Auris Medical Holding AG , Bahnhofstrasse 21, 6300 Zug, Switzerland (the " Assignor ");

 

(2) Hercules Capital, Inc. , 400 Hamilton Avenue, Suite 310, Palo Alto, CA 94301, USA (the " Agent ")

 

BACKGROUND

 

(A) Auris Medical Holding AG (as Borrower), Hercules Capital, Inc. (as Lender and Agent) and certain other lenders are parties to that certain loan and security agreement dated on or about the date hereof pursuant to which the Lender (as defined therein) has agreed to make available certain term loan advances to the Borrower (the " Loan and Security Agreement ").

 

(B) The Lender has agreed to make available to the Borrower such term loan advances conditional upon, inter alia, the Assignor assigning the Bank Account Claims (as defined below) to the Agent as security for the due and punctual satisfaction of the Secured Obligations (as defined in the Loan and Security Agreement).

 

(C) The Assignor is willing to assign for security purposes the Bank Account Claims to the Agent according to the terms of this Agreement, and the Agent is willing to accept such assignment.

 

AGREED TERMS

 

1. Interpretation and definitions

 

1.1 In this Agreement the following expressions shall have the following meanings:

 

" Account Banks " means any banks, including the banks as set forth in Schedule 1, with which the Assignor holds or will hold any Bank Accounts;

 

" Agent " means the Agent as identified in the parties list above and its permitted successors, as the case may be;

 

" Agreement " means this agreement (including its schedules) and all the terms contained in it;

 

" Assignment " means the security interest created by this Agreement pursuant to clause  2.

 

" Assignor " means the assignor as identified in the parties list above and its permitted successors, as the case may be;

 

" Bank Account Claims " means all present and future monies standing to the credit of the Bank Accounts, and all entitlements to interest accruing to any such monies, as well as any investments, securities and any other assets or rights on deposit on the Bank Accounts together with all rights and benefits relating to the above assets and rights, including privileges and ancillary rights in respect thereof;

 

" Bank Accounts " means the bank accounts of the Assignor as set forth in Schedule 1 and any Future Bank Accounts other than Excluded Accounts;

 

 

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" Business Day " means a day on which banks are open for business in Zug, Switzerland;

 

" DEBA " means the Swiss Federal Debt Enforcement and Bankruptcy Act ( Schuldbetreibungs- und Konkursgesetz ) of April 11, 1889;

 

" Effective Date " means the date first set forth above;

 

" Future Bank Accounts " means such bank accounts that the Assignor may open in the future during the term of this Agreement with any banking institution in Switzerland other than Excluded Accounts;

 

" Loan and Security Agreement " has the meaning given to it in Background (A);

 

" Party " means a party to this Agreement;

 

1.2 Terms not defined in this Agreement shall have the meaning given to them in the Loan and Security Agreement.

 

1.3 The table of contents and headings and sub-headings of this Agreement are for convenience only and shall not affect the construction of this Agreement.

 

1.4 The words "other", "include", "including" and "in particular" do not connote limitation in any way.

 

1.5 Unless the context otherwise requires, words denoting the singular shall include the plural and vice versa and references to any gender shall include all other genders.

 

1.6 References to any person (which for the purposes of this Agreement shall include bodies corporate, unincorporated associations, partnerships, trusts, governments, governmental agencies and departments, statutory bodies or other entities, in each case whether or not having a separate legal personality) shall include the person's successors.

 

1.7 References to recitals, schedules, clauses and sub-clauses are references to recitals, schedules, and clauses and sub-clauses of this Agreement (unless otherwise specified) and references within a schedule to paragraphs are to paragraphs of that schedule (unless otherwise specified).

 

1.8 References in this Agreement to any statute, ordinance, statutory provision, regulation, directive or other legislation include a reference to that legislation as amended or replaced from time to time (whether before or after the Effective Date) and include any order, regulation, instrument or other subordinate legislation made under the relevant legislation, and references in this Agreement to any agreement or document include a reference to that agreement or document (including its schedules) as varied, amended, supplemented or replaced from time to time (whether before or after the Effective Date).

 

1.9 References to any Swiss legal term for any action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official or any legal concept, state of affairs or thing shall in respect of any jurisdiction other than Switzerland be deemed to refer to and include that action, remedy, method of judicial proceeding, legal document, legal status, court, organization, body, official, legal concept, state of affairs or thing which most nearly approximates in that jurisdiction to the Swiss legal term.

 

 

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1.10 Where a German term has been inserted after an English term in italics, the German term alone shall be authoritative for the purpose of interpreting such English term, without regard to any other interpretation of the English term.

 

1.11 This Agreement is drafted in English for convenience purposes only, and the fact that the English language is used herein shall not be a reason to refer to laws, doctrine or case law of any English-speaking jurisdiction in the interpretation of this Agreement. Rather, this Agreement, and the security created hereunder, shall exclusively be interpreted by reference to Swiss laws, doctrine and case law.

 

1.12 Any reference to "writing" or "written" includes faxes and any legible reproduction of words delivered in permanent and tangible form, and PDF files transmitted by e-mail (but not plain e-mail).

 

2. Role of the Agent

 

2.1 Any reference in this Agreement to the Agent shall, unless expressly otherwise provided, be a reference to the Agent acting for its own benefit and for the benefit of the Lender.

 

3. Assignment

 

3.1 For the purpose of securing the Secured Obligations, the Assignor hereby undertakes to assign and hereby assigns by way of security assignment ( Sicherungszession ) any and all Bank Account Claims to the Agent, and the Agent hereby accepts such assignment. Where a Bank Account Claim does not yet exist on the Effective Date, its assignment shall become effective with the arising of such future Bank Account Claim ( Abtretung einer künftigen Forderung ).

 

3.2 For the avoidance of doubt and notwithstanding any provision of this Agreement to the contrary, the Parties acknowledge and agree that each assignment made under this Agreement is immediate (with effect as of the Effective Date for the initial assignment) and unconditional.

 

4. Continuing and additional security

 

4.1 The Assignment shall remain in force, and shall not be satisfied by any intermediate payment or intermediate satisfaction of any part of the Secured Obligations or by any intermediate settlement of accounts, until all of the Secured Obligations have been unconditionally and irrevocably paid in full (other than inchoate indemnity obligations) and no further Secured Obligations are capable of arising.

 

4.2 If any payment remitted in order to pay the Secured Obligations, in the course of bankruptcy proceedings, on the grounds of fraudulent preference or otherwise, is deemed capable of being avoided or set aside or ordered to be refunded or reduced, the obligations of the Assignor hereunder shall revive and the security interest constituted by this Agreement shall continue with respect to the Secured Obligations to the extent any payment thereof is deemed capable of being avoided, set aside or ordered to be refunded or reduced.

 

4.3 The Assignment shall be cumulative, and shall be in addition to, and shall not in any way be prejudiced by or dependent on any collateral or other security now or thereafter held by or for the benefit of the Agent as security for the Secured Obligations or any lien to which it may be entitled (whether by contract or statute). The rights of the Agent hereunder are in addition to and

 

 

Bank Account Claims Security Assignment Agreement 4 /11

not in lieu of those provided by law. The Assignment secures the Agent up to the amount of the Secured Obligations from time to time outstanding.

 

4.4 To the fullest extent permitted by applicable law, the Assignor waives any right it may have to require the Agent to first proceed against, or claim payment from, any person or enforce any guarantee or security granted by any person before enforcing this Agreement and/or its rights hereunder or pursuant hereto.

 

5. Variation of Secured Obligations

 

5.1 The Assignor herewith expressly agrees that the Assignment shall (to the extent legally possible) extend from time to time to any (however fundamental) variation, increase or extension of the Secured Obligations.

 

6. Representations and warranties

 

6.1 In addition to, and without in any way limiting the representations and warranties made in the other Loan Documents, but subject to the security rights created and the obligations imposed on the Assignor by virtue of this Agreement or any other Loan Document, the Assignor hereby represents and warrants that on the Effective Date and on each Advance Date:

 

(a) it is duly incorporated and validly existing under the laws of Switzerland and has the power to carry on its business as it is now being conducted and to own its property and other assets;

 

(b) this Agreement constitutes legal, valid and binding obligations of the Assignor enforceable in accordance with the terms and conditions set forth herein;

 

(c) the entering into, the execution and the performance of this Agreement have been duly authorized by all necessary corporate and other action and do not conflict with, and (with regard to agreements) do not constitute an event of default under, any provision of its articles of association or other constitutional documents or any provision of law, regulation, decision, decree, order of court, of an arbitration panel or of a public authority or any agreement, arrangement or other instrument to which the Assignor is a party or by which it or any of its assets are bound or affected;

 

(d) save for any Permitted Liens, it is the sole creditor and beneficiary of, and entitled to all rights and benefits in relation to, the Bank Account Claims;

 

(e) it has not assigned, transferred, sold or otherwise disposed of, and save for any Permitted Liens it has not encumbered, the benefit of all or any of its rights, title and interest in the Bank Account Claims;

 

(f) save for any Permitted Liens and any customary rights of set-off, pledge, retention and similar rights of the Account Banks, the Bank Account Claims are free and clear of any Liens;

 

(g) no claims or proceedings are pending or threatened in connection with the Bank Accounts or the Bank Account Claims;

 

 

Bank Account Claims Security Assignment Agreement 5 /11
(h) save for any Permitted Liens, the Bank Account Claims are fully assignable as of the date of their assignment to the Agent hereunder purportedly becoming effective.

 

6.2 The representations and warranties above are made at the time(s) as set out in clause 6.1 and are repeated as of the date of each assignment of Bank Account Claims purportedly becoming effective hereunder.

 

7. Covenants of Assignor

 

7.1 On the Closing Date, the Assignor shall deliver to the Agent a copy of the minutes of a resolution passed by the board of directors of the Assignor approving the entering into, execution and performance by the Assignor of this Agreement.

 

7.2 The Assignor undertakes and covenants for as long as any of the Secured Obligations remains unpaid or is capable of arising as follows:

 

(a) unless expressly otherwise permitted by the Loan and Security Agreement, not to enter into any legal instrument relating to, or grant or permit to be created or to subsist any Lien, other than a Permitted Lien, over, or dispose of, or waive, or assign any of the Bank Account Claims or take or permit any other action or omission that could impair or jeopardize any rights of the Agent under this Agreement, including but not limited to closing any of the Bank Accounts, or could impair or jeopardize the enforcement of the security interest under this Agreement or the value of the Bank Account Claims;

 

(b) to without delay communicate any information relating to the Future Bank Accounts, in particular the account details of such bank accounts and the name and address of the bank with which they are planned to be held, to the Agent; and

 

(c) to promptly do all things and execute all documents that are reasonably requested by the Agent from time to time for the purpose of the exercise of the Agent's rights hereunder or securing or perfecting the security interest under this Agreement.

 

8. Operation and administration of Bank Accounts

 

8.1 The Agent is exclusively entitled to collect any balance standing to the credit of the Bank Accounts.

 

8.2 The Agent, however, hereby authorizes the Assignor, subject to the provisions of the Loan and Security Agreement, to use any balance standing to the credit of the Bank Accounts in the ordinary course of its business for as long as no Event of Default has occurred and is continuing. After the occurrence of an Event of Default and during the continuance thereof, the Assignor shall not, without the prior written consent of the Agent, dispose of or collect any Bank Account Claims.

 

8.3 Notwithstanding clause 8.1 (and any other provision of this Agreement), the Parties agree that the security interest contemplated by this Agreement shall become effective as of the Effective Date.

 

8.4 If an Account Bank terminates the banking relationship with the Assignor, the Assignor shall remit the funds from the respective Bank Accounts to other bank accounts held in the name of the Assignor and such other bank accounts shall then be Bank Accounts for the purposes of

 

 

Bank Account Claims Security Assignment Agreement 6 /11

this Agreement. If the Assignor fails to do so until the date which is at least five Business Days prior to expiry of the termination period applied by the terminating Account Bank, then the Agent shall be entitled to cause remittance of the funds from the respective Bank Accounts to accounts in the name of the Agent to which representatives of the Assignor shall have signatory rights as directed by the Assignor and which shall be Bank Accounts for purposes of this Agreement. However, the Agent undertakes to ensure that the funds transferred from such Bank Account to an account held in the name of the Agent will never be commingled with funds of the Agent or any third parties.

 

9. Realization

 

9.1 Upon the occurrence of an Event of Default and during the continuance thereof, the Assignor shall, upon request of the Agent, execute all documents and do all other things that the Agent may reasonably require to facilitate the realization of the Bank Account Claims.

 

9.2 Upon the occurrence of an Event of Default and during the continuance thereof, the Agent shall without further notification at any time be, at its sole discretion, entitled, but not obligated to:

 

(a) send notices to all Account Banks in respect of all Bank Account Claims to revoke any power given to, or remaining with, the Assignor in respect of the Account Claims;

 

(b) collect the amounts standing to the credit of the Bank Accounts, in particular by withdrawing such amounts from the Bank Accounts; and/or

 

(c) realize the Bank Account Claims in full or in part through a bona fide private sale ( private Verwertung ) at fair market value or acquisition of the Bank Account Claims for its own account ( Selbsteintritt ) at fair market value, in either case without having to initiate proceedings under, and without regard to the formalities provided in, the DEBA;

 

with respect to subclauses (b) and (c), in each case applying the resulting proceeds to the discharge of the Secured Obligations in accordance with the terms of the Loan and Security Agreement. The Agent shall promptly account for the proceeds of any collection or sale.

 

9.3 Upon the occurrence of an Event of Default and during the continuance thereof, the Assignor shall without delay transfer any payment of the Bank Account Claims it receives to the account so designated by the Agent and, until such transfer occurs, shall hold the respective funds in trust for the Agent and segregated from other funds of the Assignor.

 

9.4 Nothing in this Agreement shall preclude the Agent from sending at any time on or after the Effective Date any assignment notice directly to any Account Bank upon the occurrence of an Event of Default and during the continuance thereof or if its otherwise necessary to protect the security interest under this Agreement.

 

9.5 Notwithstanding the provisions in this clause 9, the Agent is at liberty to enforce any Secured Obligations prior to the collection or enforcement of any Bank Account Claims and to commence or pursue the regular debt enforcement proceedings against the Assignor or any other debtor of any of the Secured Obligations without having first to collect or enforce any Bank Account Claims, without foregoing any of its rights hereunder.

 

9.6 If the proceeds resulting from enforcement actions pursuant to this clause 9 exceed the Secured Obligations, upon unconditional and irrevocable satisfaction of all Secured Obligations

 

 

Bank Account Claims Security Assignment Agreement 7 /11

(except for inchoate indemnity obligations) and no further Secured Obligations being capable of arising, the Agent shall promptly account for and remit the excess amount to the Assignor.

 

9.7 For the avoidance of doubt, it is expressly agreed that the Assignor shall remain liable for any Secured Obligations which are not finally settled by application of the proceeds of the realization of the Bank Account Claims ( keine Abtretung an Zahlungs Statt ).

 

10. Banking secrecy

 

10.1 The Assignor hereby irrevocably and unconditionally waives any secrecy rights to the extent necessary for the Agent to exercise its rights (including, but not limited to, its rights under clause 13) and obligations under this Agreement. For this purpose, upon request of the Agent, the Assignor shall authorize and instruct each Account Bank to disclose any information relating to the Bank Accounts to the Agent.

 

11. Audits and bank statements

 

11.1 The Agent is entitled to inspect and audit the status of the Bank Accounts Claims and to request information and production of relating documents, including documentation regarding the Bank Accounts, from the Assignor pursuant to section 7.2 of the Loan and Security Agreement.

 

12. Reassignment of Bank Account Claims

 

12.1 Upon discharge of the Secured Obligations pursuant to clause 4.1, the Agent herewith undertakes to reassign to the Assignor, at the cost of the Assignor, free and clear of any Lien created by the Agent, any and all Bank Account Claims and to do any and all acts reasonably required for such reassignment.

 

12.2 For the sake of clarity it is expressly agreed that clauses 4.2 and 13.2 shall survive the release as per clause 12.1 and – except as explicitly agreed otherwise – the termination of this Agreement for as long as respective claims are capable of arising, provided, however, that the occurrence of any claims under clause 13.2 after such release or termination shall not result in a revival of the security interest constituted by this Agreement.

 

13. Assignments and transfers

 

13.1 If a replacement or successor agent of the Agent is appointed in accordance with the terms of the Loan and Security Agreement, the Agent shall automatically be replaced by that replacement or successor agent as the respective Party to this Agreement, such replacement being valid and enforceable for and against the Assignor upon notification to the Assignor of such replacement or succession including evidence of the due (i) assignment and transfer of any and all rights and obligations of the Agent under this Agreement and (ii) assignment of the Bank Account Claims by the Agent to the successor agent.

 

13.2 The rights and obligations of the Assignor under this Agreement may not be assigned or transferred without the prior written consent of the Agent.

 

14. Expenses and indemnification

 

14.1 The Assignor's obligation to reimburse the Agent for costs, expenses, fees and damages shall be governed by section 6.3 of the Loan and Security Agreement.

 

 

Bank Account Claims Security Assignment Agreement 8 /11
14.2 Unless caused (by action or omission) intentionally or – if and to the extent the law permits – grossly negligently, the Agent shall not be liable for any losses of the Assignor arising in connection with the exercise or purported exercise of any of its rights, power and discretion under this Agreement.

 

15. Amendment and waiver

 

15.1 Any amendment of this Agreement, including any amendment of this clause 15.1, must be in writing in order to be valid.

 

15.2 A waiver of any right under this Agreement is only effective if it is in writing and it applies only to the Party to which the waiver is addressed and the circumstances for which it is given.

 

15.3 The failure or delay by a Party in exercising any right or remedy under or in connection with this Agreement will not constitute a waiver of such right or remedy.

 

15.4 No waiver of any provision of this Agreement or of any right or remedy in connection with this Agreement shall constitute a continuing waiver or a waiver relating to a subsequent breach of such provision, right or remedy under this Agreement.

 

16. Notices

 

16.1 Any notice to be given under this Agreement shall be given pursuant to section 11.2 of the Loan and Security Agreement.

 

17. Language

 

17.1 All notices or formal communications in connection with this Agreement shall be in English.

 

18. Severance

 

18.1 The invalidity of individual parts of this Agreement shall have no impact on the validity of the Agreement as a whole. The Parties agree that if any provision or part of a provision of this Agreement is deemed invalid, inoperative or otherwise not enforceable, the Agreement as a whole shall remain valid and the invalid provision or part of a provision shall be replaced by a provision which the Parties would have agreed on in good faith if they had been aware of the invalidity.

 

19. Entire agreement

 

19.1 In this clause 19, references to this Agreement include all other written agreements and arrangements between the Parties which are expressed to be supplemental to this Agreement or which this Agreement expressly preserves or requires to be executed.

 

19.2 This Agreement constitutes the whole and only understanding between the Parties in relation to its subject matter. All previous drafts, agreements, understandings, undertakings, representations, warranties, promises and arrangements of any nature whatsoever between the Parties with any bearing on the subject matter of this Agreement are superseded and extinguished to the extent that they have such a bearing and each of the Parties acknowledges to the other that it is not entering into this Agreement in consequence of or in reliance on anything it is the purpose of this clause to exclude.

 

 

Bank Account Claims Security Assignment Agreement 9 /11
19.3 The schedules to this Agreement are an integral part of this Agreement.

 

20. Governing law and jurisdiction

 

20.1 This Agreement and the security interest created hereunder shall in all respects, including without limitation the assignment of the Bank Account Claims for security purposes, be governed by and construed in accordance with Swiss substantive law.

 

20.2 The Parties submit to the exclusive jurisdiction of the competent court of Zurich 1 for all disputes arising out of or in connection with this Agreement.

 

[Remainder of page left blank intentionally; signature page follows]

 

 

Bank Account Claims Security Assignment Agreement 10 /11
Assignor Auris Medical Holding AG  
     
      
  Name:
Title:
 
     
      
  Name:
Title:
 
     
     
Agent , acting for itself and for the benefit of the other Lenders Hercules Capital, Inc.  
     
      
  Name:
Title:
 

 

Bank Account Claims Security Assignment Agreement 11 /11

Schedule 1
Bank Accounts

 

Details of Assignor's Bank Accounts

 

Bank Description Account No Currency
UBS Switzerland AG, Postfach, 8098 Zürich CHF

UBS Switzerland AG

Postfach, 8098 Zürich 

EUR

UBS Switzerland AG

Postfach, 8098 Zürich 

USD

UBS Switzerland AG

Postfach, 8098 Zürich 

USD

 

 

Exhibit 99.1

 

 

Auris Medical News Release

 

Auris Medical Secures Loan Facility of Up To $20 Million

 

Zug, Switzerland, July 19, 2016 – Auris Medical Holding AG (NASDAQ: EARS), a clinical-stage company dedicated to developing therapeutics that address important unmet medical needs in otolaryngology, today announced that it has entered into a loan facility agreement with Hercules Capital, Inc. (NYSE: HTGC), for up to $20 million in financing.

 

Auris Medical has closed the first tranche of financing of $12.5 million. Funding of a second tranche of financing of up to $7.5 million is, among other factors, subject to the Phase 3 TACTT2 clinical trial with Keyzilen TM (AM-101) meeting its co-primary endpoints.

 

“This financing provides us with greater balance sheet strength and flexibility as we advance our Phase 3 clinical development programs and prepare for the potential commercialization of Keyzilen TM ,” commented Thomas Meyer, Auris Medical’s founder, Chairman and Chief Executive Officer.

 

The financing is in the form of a 42-month loan bearing interest at a minimum rate of 9.55% per annum, and is subject to the variability of the prime interest rate. Terms include an initial interest-only period until June 30, 2017, which is extendable to March 31, 2018, subject to certain conditions. Auris Medical issued Hercules a warrant to purchase up to 241,117 shares of the Company's common stock at an exercise price of $3.94 per share.

 

About Auris Medical

 

Auris Medical is a Swiss biopharmaceutical company dedicated to developing therapeutics that address important unmet medical needs in otolaryngology. The Company is currently focusing on the Phase 3 development of treatments for acute inner ear tinnitus (Keyzilen TM ; AM-101) and for acute inner ear hearing loss (AM-111) by way of intratympanic administration with biocompatible gel formulations. In addition, Auris Medical is pursuing early-stage research and development projects. The Company was founded in 2003 and is headquartered in Zug, Switzerland. The shares of the parent company Auris Medical Holding AG trade on the NASDAQ Global Market under the symbol "EARS."

 

About Hercules Capital, Inc.

 

Hercules Capital, Inc. (NYSE: HTGC) (“Hercules”) is the leading and largest specialty finance company focused on providing senior secured venture growth loans to high-growth, innovative venture capital-backed companies in a broad variety of technology, life sciences and sustainable and renewable technology industries. Since inception (December 2003), Hercules has committed more than $6.0 billion to over 350 companies and is the lender of choice for entrepreneurs and venture capital firms seeking growth capital financing.

 

Forward-looking Statements

 

This press release may contain statements that constitute “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements are statements other than historical fact and may include statements that address future operating, financial or business performance or Auris Medical’s strategies or expectations. In some cases, you can identify these statements by forward-looking words such as “may,” “might,” “will,” “should,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “predicts,” “projects,” “potential,” “outlook” or “continue,” and other comparable terminology. Forward-looking statements are based on management’s current expectations and beliefs and involve significant risks and uncertainties that could cause actual results, developments and business decisions to differ materially from those contemplated by these statements. These risks and uncertainties include, but are not limited to, the timing and conduct of clinical trials of Auris Medical’s product candidates, the clinical utility of Auris Medical’s product candidates, the timing or likelihood of regulatory filings and approvals, Auris Medical’s intellectual property position and Auris Medical’s financial position, including the impact of any future acquisitions, dispositions, partnerships, license transactions or changes to Auris Medical’s capital structure, including future securities offerings. These risks and uncertainties also include, but are not limited to, those described under the caption “Risk Factors” in Auris Medical’s Annual Report on Form 20-F and future filings with the Securities and Exchange Commission. Forward-looking statements speak only as of the date they are made, and Auris Medical does not undertake any obligation to update them in light of new information, future developments or

 

 

 

otherwise, except as may be required under applicable law. All forward-looking statements are qualified in their entirety by this cautionary statement.

 

Contact: Cindy McGee, Head of Investor Relations and Corporate Communications, +41 61 201 1350,

 

investors@aurismedical.com