Table of Contents

 
 
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
ARQULE, INC.
(Exact Name of registrant as specified in its charter)
         
Delaware       58-1959440
         
(State or other jurisdiction of       (I.R.S. Employer
incorporation or organization)       Identification No.)
19 Presidential Way,
Woburn, Massachusetts 01801
(Address, including zip code, of principal executive offices)
ArQule, Inc. 2005 Director Stock Compensation Plan
(Full title of the plan)
Dr. Stephen A. Hill
President and Chief Executive Officer
ArQule, Inc.
19 Presidential Way,
Woburn, Massachusetts 01801
(781) 994-0300
(Name, address, including zip code, and telephone number including area code, of agent for service)
Copy to:
Richard E. Baltz, Esq.
Arnold & Porter
555 12 th Street, N.W.
Washington, D.C. 20004
(202) 942-5124
 
Calculation of Registration Fee
                                             
 
  Title of securities to be     Amount to be     Proposed     Proposed maximum     Amount of  
  registered     registered (1)     maximum offering     aggregate offering     registration fee  
                  price per unit (2)(3)     price (3)            
 
Common Stock, $.01 par value
      250,000       $ 7.03       $ 1,757,500       $ 188.05    
 
 
(1)   Pursuant to Rule 416, promulgated under the Securities Act of 1933, as amended, an additional undeterminable number of shares of Common Stock is being registered to cover any adjustment in the number of shares of Common Stock issuable pursuant to the anti-dilution provisions of the 2005 Director Stock Compensation Plan.
 
(2)   Calculated on the basis of the average of the high and low sale prices of the Registrant’s Common Stock as reported on December 1, 2005 on the Nasdaq National Market which date is within 5 business days prior to the date of the filing of this Registration Statement.
 
(3)   Estimated solely for the purpose of determining the registration fee in accordance with Rule 457(h).
 
 

 


TABLE OF CONTENTS

PART II
Item 3. Incorporation of Documents by Reference
Item 8. Exhibits
SIGNATURES
INDEX TO EXHIBITS
EX-4 2005 DIRECTOR STOCK COMPENSATION PLAN
EX-5 OPINION OF ROBERT J. CONNAUGHTON, JR.
EX-23.2 CONSENT OF PRICEWATERHOUSECOOPERS LLP
EX-24 POWER OF ATTORNEY


Table of Contents

PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. Incorporation of Documents by Reference .
     The following documents filed by the Company (File No. 000-21429) with the Commission under the Securities Exchange Act of 1934, as amended (“Exchange Act”), are incorporated herein by reference:
(a)   The Company’s Annual Report on Form 10-K for the year ended December 31, 2004, filed with the Commission on March 16, 2005;
(b)   The Company’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2005, filed with the Commission on April 29, 2005;
(c)   The Company’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2005, filed with the Commission on August 5, 2005;
(d)   The Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2005, filed with the Commission on November 4, 2005;
(e)   The Company’s Current Reports on Form 8-K filed with the Commission on January 24, 2005, January 25, 2005, January 31, 2005, February 18, 2005, April 7, 2005, April 11, 2005, May 6, 2005, June 15, 2005; September 16, 2005, September 30, 2005, October 17, 2005, and November 17, 2005; and
(f)   The description of the Company’s Common Stock contained in a registration statement on Form 8-A filed with the Commission on September 25, 1996, and any amendments or reports filed for the purpose of updating such description.
     All documents filed by the Registrant after the date of this Registration Statement pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-effective amendment which indicates that all Common Stock offered hereby has been sold or which deregisters such Common Stock then remaining unsold, shall be deemed to be incorporated in this Registration Statement by reference and shall be a part hereof from the date of filing of such documents. Any statement contained in a document incorporated or deemed to be incorporated by reference in this Registration Statement shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference in this Registration Statement modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or so superseded, to constitute a part of this Registration Statement.

 


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Item 8.     Exhibits
     
Exhibit 4
  ArQule, Inc. 2005 Director Stock Compensation Plan.
 
   
Exhibit 5
  Opinion of Robert J. Connaughton, Jr., filed herewith.
 
   
Exhibit 23.1
  Consent of Robert J. Connaughton, Jr., included in the opinion filed as Exhibit 5 hereto.
 
   
Exhibit 23.2
  Consent of PricewaterhouseCoopers LLP, independent registered public accounting firm, filed herewith.
 
   
Exhibit 24
  Powers of Attorney of certain officers and directors of ArQule, Inc., filed herewith.

 


Table of Contents

SIGNATURES
     Pursuant to the requirements of the Securities Act of 1933, as amended, the Company certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned thereunto duly authorized in the City of Woburn,
     Commonwealth of Massachusetts, on December 5, 2005.
         
  ARQULE, INC.
 
 
  By:   /s/ Stephen A. Hill    
    Stephen A. Hill   
    President and Chief Executive Officer   
 
     Pursuant to the requirements of the Securities Act of 1933, as amended, this registration statement has been signed by the following persons in the capacities and on the dates indicated:
         
Signature   Title   Date
/s/ Stephen A. Hill
 
Stephen A. Hill
  President, Chief Executive Officer and Director (Principal Executive Officer)   December 5, 2005
/s/ Louise A. Mawhinney
 
Louise A. Mawhinney
  Vice President, Chief Financial Officer, Treasurer and Secretary (Principal Accounting and Financial Officer)   December 5, 2005
/s/ Patrick J. Zenner
 
Patrick J. Zenner
  Chairman of the Board   December 5, 2005
/s/ Michael J. Astrue
 
Michael J. Astrue
  Director   December 5, 2005
/s/ Laura Avakian
 
Laura Avakian
  Director   December 5, 2005
/s/ Timothy C. Barabe
 
Timothy C. Barabe
  Director   December 5, 2005
/s/ Werner Cautreels
 
Werner Cautreels
  Director   December 5, 2005
/s/ Tuan Ha-Ngoc
 
Tuan Ha-Ngoc
  Director   December 5, 2005
/s/ Ronald M. Lindsay
 
Ronald M. Lindsay
  Director   December 5, 2005
/s/ William G. Messenger
 
William G. Messenger
  Director   December 5, 2005

 


Table of Contents

INDEX TO EXHIBITS
     
Exhibit 4
  ArQule, Inc. 2005 Director Stock Compensation Plan, filed herewith.
 
   
Exhibit 5
  Opinion of Robert J. Connaughton, Jr., filed herewith.
 
   
Exhibit 23.1
  Consent of Robert J. Connaughton, Jr., included in the opinion filed as Exhibit 5 hereto.
 
   
Exhibit 23.2
  Consent of PricewaterhouseCoopers LLP, independent registered public accounting firm, filed herewith.
 
   
Exhibit 24
  Powers of Attorney of certain officers and directors of ArQule, Inc., filed herewith.

 

 

Exhibit 4
ARQULE, INC.
2005 DIRECTOR STOCK COMPENSATION PLAN
1. ESTABLISHMENT. ArQule, Inc. (the “Company”) hereby establishes the ArQule, Inc. 2005 Director Stock Compensation Plan (this “Plan”) for its Eligible Directors whereby such directors may elect to receive compensation for their services in the form of shares of common stock, $0.01 par value, of the Company (“Common Stock”) in lieu of fees payable in cash.
2. DEFINITIONS.
For purposes of this Plan, the following terms shall have the following meanings:
     2.1 “Authorized Shares” means the total number of shares of Common Stock available during the term of this Plan as set forth in Section 5 hereof.
     2.2 “Board” means the Board of Directors of the Company.
     2.3 “Committee” means a committee of the Board of not fewer than two members, each of whom shall be a “non-employee director” or the equivalent within the meaning of Rule 16b-3 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Unless otherwise designated by the Board, the “Committee” shall mean the Compensation, Nominating and Governance Committee of the Board.
     2.4 “Compensation” means the annual retainer, meeting fees, committee fees and other compensation payable to an Eligible Director during his or her term in office under the Company’s compensation policies for members of the Board in effect from time to time.
     2.5 “Eligible Director” means an individual who is a member of the Board, but who is not an employee of the Company.
     2.6 “Fair Market Value” of a share of Common Stock means its closing sale price on the business day immediately preceding the relevant Payment Date as reported on the Nasdaq National Market (or such other quotation system or securities exchange on which shares of the Common Stock are quoted or listed if such shares are no longer quoted on the Nasdaq National Market). If shares of the Common Stock are not quoted on a quotation system or listed on a securities exchange, “Fair Market Value” shall be determined by the Committee in good faith or in the manner established by the Committee from time to time.
     2.7 “Payment Date” means the business day on which any payment of Compensation is made under the Company’s compensation policies for members of the Board in effect from time to time; provided, however, that the Payment Date for Compensation in respect of a calendar year shall not be later than March 15th of the following calendar year.

 


 

3. PURPOSE. The purpose of this Plan is to attract and retain highly qualified, non-employee directors of the Company and to encourage ownership of stock of the Company by those directors so as to further align the interests of non-employee directors and stockholders in promoting the success of the Company.
4. EFFECTIVE DATE. The effective date of this Plan (the “Effective Date”) is the later of (i) the date of its approval by the Board, or (ii) the effective date of any registration statement under the Securities Act of 1933, as amended, registering the shares of Common Stock issuable hereunder.
5. STOCK SUBJECT TO THIS PLAN. Subject to adjustment in accordance with Section 9 hereunder, the total number of shares of Common Stock available during the term of this Plan shall be two hundred and fifty thousand (250,000) shares. Shares of Common Stock to be delivered under this Plan shall be made available from presently authorized but unissued Common Stock or authorized and issued shares of Common Stock reacquired and held as treasury shares, or a combination thereof. In no event shall the Company be required to issue fractional shares of Common Stock under this Plan.
6. ADMINISTRATION OF THIS PLAN. The Committee shall administer this Plan. The Committee shall have the authority and discretion to adopt, alter and repeal such administrative rules, guidelines and practices governing the operation of this Plan as it shall from time to time consider necessary or advisable, and to interpret the provisions of this Plan. The Committee shall have all of the powers necessary to enable it to properly carry out its duties under this Plan. To the extent permitted by applicable law, the Committee may delegate to one or more executive officers of the Company such powers and duties as the Committee may deem necessary or advisable that are not inconsistent with the intent of this Plan. Decisions of the Committee upon all matters within its scope of authority shall be final and conclusive on all persons, except to the extent otherwise provided by law.
7. ELECTION TO RECEIVE COMPENSATION IN SHARES OF COMMON STOCK.
     (a)  Election Procedure . Each Eligible Director may elect to forego receipt of all or a portion of his or her Compensation in exchange for Common Stock issued under this Plan. The number of shares of Common Stock received by any Eligible Director on a Payment Date hereunder shall equal the amount of foregone cash Compensation divided by the Fair Market Value of a share of Common Stock on the relevant Payment Date, rounded down to the nearest whole share, with the dollar amount of any fractional share paid in cash on the Payment Date .
     (b)  Standing Election; Modification or Termination . Eligible Directors may participate in this Plan by submitting a written or electronic election to the Chief Financial Officer of the Company, in such form as the Company determines, at least three (3) months prior to the first Payment Date to which the election relates. Such election shall continue in effect until modified or terminated by means of a subsequent written or electronic election submitted to the Chief Financial Officer of the Company, in such form

2


 

as the Company determines, at least three (3) months prior to the Payment Date to which the modification or termination relates.
      (c) Inside Information . Any election made by an Eligible Director hereunder shall be made (i) during an open trading window when the Eligible Director is not in possession of material nonpublic information, and (ii) in accordance with the Company’s “Policy Regarding Trading in ArQule Securities”, or similar successor policy.
      (d) Share Shortfalls . If any election under this Plan would cause the number of shares of Common Stock required to be issued under this Plan to exceed the Authorized Shares, then any then current elections of Eligible Directors shall be reduced or disregarded to the extent necessary, as determined by the Committee in an equitable manner, to avoid exceeding the Authorized Shares. No further elections shall be made or shall be valid until such time, if any, as additional shares of Common Stock become available for purchase under this Plan.
     (e)  Delivery of Shares. As soon as practicable after each Payment Date, but in no event later than March 15 th of the calendar year following the calendar year to which the forgone Compensation relates, the Company shall cause a share certificate to be issued to, or an entry to be made in the authorized brokerage account of, each participating Eligible Director for the number of shares of Common Stock due to him or her pursuant to any election hereunder. No adjustment shall be made for a dividend or other right for which the record date is prior to the date the stock certificate is issued or authorized brokerage account entry made.
8. RESALE OF SHARES. The Company may impose such restrictions on the sale or other disposition of shares of Common Stock issued under this Plan as the Committee shall deem necessary or advisable to comply with relevant provisions of any applicable laws, rules and regulations, including, without limitation, the Securities Act of 1933, as amended, the Exchange Act, any applicable rules and regulations thereunder, state securities laws, and the requirements of the Nasdaq National Market (or such other quotation system or securities exchange on which the Common Stock is quoted or listed if the Common Stock is no longer quoted on the Nasdaq National Market) (collectively, “applicable securities laws and regulations”) now or hereafter in effect. Certificates for shares of Common Stock issued under this Plan may bear such legends as the Company deems necessary or advisable to give notice of such restrictions.
9. ADJUSTMENT FOR CHANGES IN CAPITALIZATION. The number of shares of Common Stock authorized for issuance under this Plan shall be proportionately adjusted for any increase or decrease in the number of issued shares of Common Stock resulting from a stock split, reverse stock split, stock dividend, recapitalization, reorganization, merger, consolidation, split-up, spin-off, combination, exchange or reclassification of the Common Stock, or any other increase or decrease in the number of issued shares of Common Stock effected without receipt of consideration by the Company; provided, however, that conversion of any convertible securities of the Company shall not be deemed to have been “effected without receipt of consideration.”

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10. CONDITIONS UPON ISSUANCE OF COMMON STOCK.
     (a)  Regulatory Compliance. Shares of Common Stock shall not be issued hereunder unless their issuance and delivery shall comply with all applicable securities laws and regulations.
     (b)  Investment Representation. As a condition to issuance hereunder, the Company may require a participating Eligible Director to represent and warrant as of the relevant Payment Date that the shares of Common Stock issued hereunder are being acquired only for investment and without any present intention to sell or distribute such shares of Common Stock, if, in the Company’s opinion, such representation is required by applicable securities laws and regulations now or hereafter in effect.
     (c)  Regulatory Authorization. Any inability of the Company to obtain authority from any regulatory body having jurisdiction over the Company or the transactions contemplated by this Plan, which authority is deemed by the Company to be necessary or advisable for the lawful issuance and delivery of any shares of Common Stock hereunder, shall relieve the Company of any liability in respect of its failure to issue or deliver such shares of Common Stock as to which such requisite authority shall not have been obtained. In such case, the Company’s obligations hereunder shall be satisfied by payment of the cash Compensation for which such shares of Common Stock were to be exchanged.
11. TERMINATION AND AMENDMENT OF PLAN. Unless terminated sooner as provided herein, this Plan shall terminate ten (10) years from the date that it is adopted by the Board. The Board may at any time amend, alter, suspend or terminate this Plan, subject to stockholder approval if required under the applicable securities laws and regulations.
12. RIGHTS AS A STOCKHOLDER. An Eligible Director shall have no rights as a stockholder with respect to Common Stock issued to him or her under this Plan on the relevant Payment Date until the date of issuance of the stock certificate or making of the entry in an authorized brokerage account representing such shares. Except as provided in Section 9, no adjustment will be made for dividends or other rights for which the record date is prior to the date such Common Stock is issued.
13. GOVERNING LAW. The provisions of this Plan shall be governed by and interpreted in accordance with the laws of Delaware.
The Board of Directors authorized this Plan on November 11, 2005. Stockholder approval of this Plan was not required.

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Exhibit 5
Robert J. Connaughton, Jr.
Corporate Counsel
rconnaughton@arqule.com
Direct Tel. 781.994.0462
Direct Fax 781.994.0587
December 5, 2005
ArQule, Inc.
19 Presidential Way
Woburn, MA 01801
Ladies and Gentlemen:
      I am rendering this opinion in connection with the Registration Statement on Form S-8 (the “Registration Statement”) filed by ArQule, Inc. (the “Company”) with the Securities and Exchange Commission (the “Commission”) under the Securities Act of 1933, as amended (the “Act”), on or about the date hereof. The Registration Statement relates to 250,000 shares of the Company’s Common Stock, $0.01 par value (the “Shares”), offered pursuant to the provisions of the Company’s 2005 Director Stock Compensation Plan (the “Plan”).
      I am Corporate Counsel for the Company and have acted in connection with the preparation of the Registration Statement. I am familiar with the proceedings taken by the Company regarding authorization, issuance and sale of the Shares. I have examined all such corporate records of the Company as I consider necessary to enable me to render this opinion including the Plan, the Company’s Amended and Restated Certificate of Incorporation, its By-laws, and votes of the Board of Directors and stockholders of the Company, as well as made such investigation of matters of fact and law and examined such other documents as I deemed necessary for rendering the opinions hereinafter expressed. The opinions set forth herein are subject to the following qualifications, which are in addition to any other qualifications contained herein:
  A.   I have assumed without verification the genuineness of all signatures on all documents, the authority of the parties (other than the Company) executing such documents, the authenticity of all original documents, and the conformity to original documents of all copies.
 
  B.   The opinions set forth herein are based on existing laws, ordinances, rules, regulations, court and administrative decisions as they presently have been interpreted and I can give no assurances that my opinions would not be different after any change in any of the foregoing occurring after the date hereof.

 


 

  C.   I express no opinion as to the effect or application of any laws or regulations other than the general corporation law of the State of Delaware and the federal laws of the United States.
      Based upon, subject to and limited by the foregoing, I am of the opinion that, under the General Corporation Law of the State of Delaware, the 250,000 shares of Common Stock issuable pursuant to the Plan have been duly authorized by the Company and, when issued and delivered in accordance with the terms of the Plan and for legal consideration of not less than $0.01 per share, the Shares will be validly issued, fully paid and nonassessable.
      This letter does not address any matters other than those expressly addressed herein and is given for the sole benefit and use of the Company. No one else is entitled to rely hereupon.
      I hereby consent to filing of this opinion as Exhibit 5 to the Registration Statement. By giving such consent I do not thereby admit that I am within the category of persons whose consent is required under Section 7 of the Securities Act of 1933, as amended, or the rules and regulations of the Securities and Exchange Commission thereunder.
     
 
  Sincerely,
 
   
 
  /s/ Robert J. Connaughton, Jr.
 
   
 
  Robert J. Connaughton, Jr.
:dms
   

 

 

Exhibit 23.2
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 16, 2005 relating to the financial statements, management’s assessment of the effectiveness of internal control over financial reporting and the effectiveness of internal control over financial reporting, of ArQule, Inc., which appears in ArQule, Inc.’s Annual Report on Form 10-K for the year ended December 31, 2004.
/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP
Boston, Massachusetts
December 2, 2005

 

 

Exhibit 24
POWER OF ATTORNEY
ArQule, Inc. 2005 Director Stock Compensation Plan
     KNOW ALL PERSONS BY THESE PRESENTS, that each undersigned director and/or officer of ArQule, Inc., a corporation organized under the laws of the state of Delaware (the “Company”), hereby constitutes and appoints each of Stephen A. Hill, Louise A. Mawhinney and Robert J. Connaughton, Jr. (each, an “Agent”, and collectively, “Agents”) his or her true and lawful attorney-in-fact and agent for and in his or her name, place and stead, in any and all capacities, to sign execute and affix his or her seal to and file with the Securities and Exchange Commission (or any other governmental or regulatory authority) a Registration Statement on Form S-8 or any other appropriate form and all amendments or supplements (including post-effective amendments) thereto with all exhibits and any and all documents required to be filed therewith or with respect thereto, relating to the registration of 250,000 shares of common stock, par value $0.01 per share, of the Company (the “Common Stock”) issuable pursuant to the ArQule, Inc. 2005 Director Stock Compensation Plan. Each signatory further grants to the Agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary, in the judgment of such Agent, to be done in connection with any such signing and filing, as full to all intents and purposes as he or she might or could do in person, and hereby ratifies and confirms all that said Agents, or any of them, may lawfully do or cause to be done by virtue hereof.
     This Power of Attorney may be executed simultaneously in one or more counterparts, each of which shall be deemed an original, but all of which constitute but one and the same instrument.
         
Signature   Title   Date
 
   
/s/ Stephen A. Hill
 
Stephen A. Hill
  President, Chief Executive Officer and Director (Principal Executive Officer)   December 5, 2005
/s/ Louise A. Mawhinney
 
Louise A. Mawhinney
  Vice President, Chief Financial Officer, Treasurer and Secretary (Principal Accounting and Financial Officer)   December 5, 2005
/s/ Patrick J. Zenner
 
Patrick J. Zenner
  Chairman of the Board   December 5, 2005
/s/ Michael J. Astrue
 
Michael J. Astrue
  Director   December 5, 2005
/s/ Laura Avakian
 
Laura Avakian
  Director   December 5, 2005

 


 

         
/s/ Timothy C. Barabe
 
Timothy C. Barabe
  Director   December 5, 2005
/s/ Werner Cautreels
 
Werner Cautreels
  Director   December 5, 2005
/s/ Tuan Ha-Ngoc
 
Tuan Ha-Ngoc
  Director   December 5, 2005
/s/ Ronald M. Lindsay
 
Ronald M. Lindsay
  Director   December 5, 2005
/s/ William G. Messenger
 
William G. Messenger
  Director   December 5, 2005