SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10 - Q

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934
For the quarterly period ended March 31, 2000

OR

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934
For the transition period from ______________ to _____________

COMMISSION FILE NUMBER 1-10352

COLUMBIA LABORATORIES, INC.
(Exact name of Company as specified in its charter)

          DELAWARE                                            59-2758596
(State or other jurisdiction of                            (I.R.S. Employer
 incorporation or organization)                           Identification No.)

   2875 N.E. 191ST STREET, SUITE 400
           AVENTURA, FLORIDA                                     33180
(Address of principal executive offices)                       (Zip Code)

Company's telephone number, including area code: (305) 933-6089

Indicate by check mark whether the Company (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Company was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes X No

Number of shares of the Common Stock of Columbia Laboratories, Inc. issued and outstanding as of May 1, 2000: 30,433,926


COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

PART 1 - FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS

The following unaudited, condensed consolidated financial statements of the Company have been prepared in accordance with the instructions to Form 10-Q and, therefore, omit or condense certain footnotes and other information normally included in financial statements prepared in accordance with generally accepted accounting principles. In the opinion of management, all adjustments (consisting only of normal recurring accruals) necessary for a fair presentation of the financial information for the interim periods reported have been made. Results of operations for the three months ended March 31, 2000 are not necessarily indicative of the results for the year ending December 31, 2000.

Except for historical information contained herein, the matters discussed in this document are forward looking statements made pursuant to the safe harbor provisions of the Securities Litigation Reform Act of 1995. Such statements involve risks and uncertainties, including but not limited to economic, competitive, governmental and technological factors affecting the Company's operations, markets, products and prices, and other factors discussed elsewhere in this report.

2

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

                                                                                     March 31,         December 31,
                                                                                       2000                1999
                                                                                   -------------      -------------
                                                                                    (Unaudited)
ASSETS
   Current assets-
      Cash and cash equivalents                                                    $   5,501,774      $   1,982,085
      Accounts receivable, net                                                         2,438,558          1,835,086
      Inventories                                                                      1,428,843          1,848,816
      Prepaid expenses                                                                   407,254            468,948
      Other current assets                                                               311,442            568,259
                                                                                   -------------      -------------
         Total current assets                                                         10,087,871          6,703,194

   Property and equipment, net                                                           902,709          1,008,553
   Intangible assets, net                                                              5,955,088          4,860,212
   Other assets                                                                          408,588            415,654
                                                                                   -------------      -------------
   TOTAL ASSETS                                                                    $  17,354,256      $  12,987,613
                                                                                   =============      =============
LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIENCY)
   Current liabilities-
      Accounts payable                                                             $   1,492,949      $   2,089,260
      Accrued expenses                                                                 1,072,250          1,072,567
      Deferred revenue                                                                   100,000            100,000
                                                                                   -------------      -------------
         Total current liabilities                                                     2,665,199          3,261,827

      Convertible subordinated note payable                                           10,000,000         10,000,000
                                                                                   -------------      -------------
         TOTAL LIABILITIES                                                            12,665,199         13,261,827

    Stockholders' equity (deficiency)-
       Preferred stock, $.01 par value; 1,000,000 shares authorized:
          Series A Convertible Preferred Stock, 33 and 923
            shares issued and outstanding in 2000 and 1999, respectively                      --                  9
          Series B Convertible Preferred Stock, 1,630
            shares issued and outstanding in 2000 and 1999                                    16                 16
          Series C Convertible Preferred Stock, 4,310 and
            5,260 shares issued and outstanding in 2000 and 1999, respectively                43                 53
      Common stock, $.01 par value; 40,000,000 shares
          authorized; 30,412,641 shares and 29,124,686
         issued and outstanding in 2000 and 1999, respectively                           304,126            291,246
      Capital in excess of par value                                                 105,939,456         99,575,803
      Accumulated deficit                                                           (101,560,544)      (100,198,848)
      Accumulated other comprehensive income                                               5,960             57,507
                                                                                   -------------      -------------
         TOTAL STOCKHOLDERS' EQUITY (DEFICIENCY)                                       4,689,057           (274,214)
                                                                                   -------------      -------------
 TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIENCY)                           $  17,354,256      $  12,987,613
                                                                                   =============      =============

See notes to condensed consolidated financial statements

3

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)

                                            Three Months Ended March 31,
                                               2000              1999
                                           ------------      ------------
NET SALES                                  $  2,989,930      $  5,466,461

COST OF GOODS SOLD                            1,219,848         1,776,841
                                           ------------      ------------
     Gross profit                             1,770,082         3,689,620
                                           ------------      ------------
OPERATING EXPENSES:
     Selling and distribution                   812,870           857,827
     General and administrative                 788,128         1,484,598
     Research and development                 1,363,412         1,390,076
                                           ------------      ------------
        Total operating expenses              2,964,410         3,732,501
                                           ------------      ------------
        Loss from operations                 (1,194,328)          (42,881)
                                           ------------      ------------
OTHER INCOME (EXPENSE):
     License fees, net of expenses                   --           387,500
     Interest income                             28,304            30,496
     Interest expense                          (188,838)         (188,838)
     Other, net                                  (6,834)          (21,167)
                                           ------------      ------------
                                               (167,368)          207,991
                                           ------------      ------------
     Income (loss) before income taxes       (1,361,696)          165,110
     Provision for income taxes                      --            25,000
                                           ------------      ------------
        Net income (loss)                    (1,361,696)     $    140,110
                                           ============      ============
NET INCOME (LOSS) PER COMMON SHARE:
     Basic                                 $       (.05)     $        .00
                                           ============      ============
     Diluted                               $       (.05)     $        .00
                                           ============      ============
WEIGHTED AVERAGE NUMBER OF COMMON AND
POTENTIAL COMMON SHARES OUTSTANDING:
     Basic                                   29,527,163        28,685,000
                                           ============      ============
     Diluted                                 29,527,163        28,985,000
                                           ============      ============

See notes to condensed consolidated financial statements

4

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE OPERATIONS
(UNAUDITED)

                                                 Three Months Ended March 31,
                                                     2000             1999
                                                 -----------      -----------
NET INCOME (LOSS)                                $(1,361,696)     $   140,110

Other comprehensive income (loss):
    Foreign currency translation, net of tax          51,547           38,290
                                                 -----------      -----------
Comprehensive income (loss)                      $(1,310,149)     $   178,400
                                                 ===========      ===========

See notes to condensed consolidated financial statements.

5

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)

                                                         Three Months Ended March 31,
                                                             2000             1999
                                                         -----------      -----------
CASH FLOWS FROM OPERATING ACTIVITIES:
   Net income (loss)                                     ($1,361,696)     $   140,110
   Adjustments to reconcile net income (loss) to net
    cash used in operating activities-
     Depreciation and amortization                           241,322          259,725
     Issuance of warrants for consulting services              5,681           12,699

   Changes in assets and liabilities-
    (Increase) decrease in:
     Accounts receivable                                    (603,472)      (2,482,146)
     Inventories                                             419,973          628,971
     Prepaid expenses                                         61,694         (253,825)
     Other assets                                            263,883            6,062

   Increase (decrease) in:
     Accounts payable                                       (596,311)        (976,448)
     Accrued expenses                                       (425,317)        (337,395)
                                                         -----------      -----------
   Net cash used in operating activities                  (1,994,243)      (3,002,247)
                                                         -----------      -----------
CASH FLOWS FROM INVESTING ACTIVITIES:
   Purchase of property and equipment                         (5,354)          (4,406)
   Acquisition of licensing rights                          (200,000)        (100,000)
                                                         -----------      -----------
     Net cash used in investing activities                  (205,354)        (104,406)
                                                         -----------      -----------
CASH FLOWS FROM FINANCING ACTIVITIES:
   Proceeds from issuance of preferred stock                      --        5,939,534
   Dividends paid                                            (62,404)        (181,625)
   Proceeds from exercise of options and warrants          5,833,237               --
                                                         -----------      -----------
     Net cash provided by financing activities             5,770,833        5,757,909
                                                         -----------      -----------

(Continued)

6

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)

(Continued)

                                            Three Months Ended March 31,
                                               2000             1999
                                            -----------      -----------
EFFECT OF EXCHANGE RATE CHANGES ON CASH         (51,547)         (45,047)
                                            -----------      -----------
NET INCREASE IN CASH
    AND CASH EQUIVALENTS                      3,519,689        2,606,209

CASH AND CASH EQUIVALENTS,
    Beginning of period                       1,982,085          315,288
                                            -----------      -----------
CASH AND CASH EQUIVALENTS,
    End of period                           $ 5,501,774      $ 2,921,497
                                            ===========      ===========

See notes to condensed consolidated financial statements

7

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
(Unaudited)

(1) SIGNIFICANT ACCOUNTING POLICIES:

The accounting policies followed for quarterly financial reporting are the same as those disclosed in Note (1) of the Notes to Consolidated Financial Statements included in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 1999.

(2) INVENTORIES:

                    March 31,    December 31,
                      2000           1999
                   ----------    ------------
Finished goods     $  688,190     $1,029,574
Raw materials         740,653        819,242
                   ----------     ----------
                   $1,428,843     $1,848,816
                   ==========     ==========

(3) SEGMENT INFORMATION:

The Company and its subsidiaries are engaged in one line of business, the development and sale of pharmaceutical products and cosmetics. The following table shows selected information by geographic area:

                                       NET           LOSS FROM     IDENTIFIABLE
                                      SALES         OPERATIONS        ASSETS
                                   ------------    ------------    ------------
As of and for the three months
 ended March 31, 2000-
      United States                $  2,412,784    $   (144,827)   $ 13,127,361
      Europe                            577,146      (1,049,501)      4,226,895
                                   ------------    ------------    ------------
                                   $  2,989,930    $ (1,194,328)   $ 17,354,256
                                   ============    ============    ============

As of and for the three months
 ended March 31, 1999-
      United States                $  4,498,887    $  1,228,563    $ 11,391,018
      Europe                            967,574      (1,271,444)      5,040,357
                                   ------------    ------------    ------------
                                   $  5,466,461    $    (42,881)   $ 16,431,375
                                   ============    ============    ============

8

(4) INCOME (LOSS) PER COMMON AND POTENTIAL COMMON SHARE:

The calculation of basic and diluted income (loss) per common and potential common share is as follows:

                                                               Three Months Ended March 31,

                                                                  2000              1999
                                                              ------------      ------------
Net income (loss)                                             $ (1,361,696)     $    140,110
   Less: preferred stock dividends                                 (62,404)          (59,968)
                                                              ------------      ------------
Net income (loss) applicable to common stock                    (1,424,100)           80,142
                                                              ============      ============
Basic:
   Weighted average number of common shares outstanding         29,527,163        28,685,000
                                                              ============      ============
   Basic net income (loss) per common share                   $       (.05)     $        .00
                                                              ============      ============
Diluted:
   Weighted average number of common shares outstanding         29,527,163        28,685,000
   Weighted average number of potential common shares                   --           300,000
                                                              ------------      ------------
   Weighted average number of common and potential common
       shares outstanding                                       29,527,163        28,985,000
                                                              ============      ============
   Diluted net income (loss) per common share                 $       (.05)     $        .00
                                                              ============      ============

(5) LAWSUIT SETTLEMENT:

The Company filed an action in the United States District Court for the Southern District of Florida ("Florida Action") in November 1997 seeking a declaratory judgment on certain issues related to its relationship with Lake Consumer Products, Inc. ("Lake") as governed in the contract between the Company and Lake. Lake filed an action against the Company in the United States District Court, Northern District of Illinois ("Illinois Action") , for damages alleged by Lake to have been suffered by it as a result of the FDA's allegations in July 1997 that the Company's nonoxynol-9 product, then marketed by Lake under the tradename Advantage 24, was not permitted to be sold under the monograph. The Illinois Action was dismissed by the Illinois Court and transferred to the Florida Court for consolidation as a counterclaim in the Florida Action. On March 16, 2000, the Company and Lake settled all outstanding issues in the consolidated Florida Action by the Company having bought out the contract for the sum of $1,200,000 ($600,000 in cash and $600,000 in the form of Company common stock). As a result, the Company reacquired the U.S. rights to the Advantage product and both parties agreed to have their legal actions dismissed. The total amount of the settlement plus certain attorney's fees, related solely to the reacquisition of the product rights, have been capitalized as part of intangible assets in the accompanying balance sheets.

9

(6) SUBSEQUENT EVENT:

Effective May 5, 2000, the Company sold various tangible and intangible assets related to the U.S. rights for Replens for a total of $4.5 million cash. Additionally, the purchaser agreed to buy up to $500,000 of Replens inventory from the Company and to pay future royalties of up to $2 million equal to 10% of future U.S. sales of Replens based.

Additionally, effective May 5, 2000, the Company licensed its Legatrin PM, Legatrin GCM, Vaporizer in a Bottle and Diasorb brands to the same purchaser mentioned above. Under the terms of these agreements, the Company will receive license fees equal to 20% of the licensee's net sales of these brands. These agreements each have five-year terms with provisions for renewal and contain options that allow the licensee to acquire the brands from the Company.

10

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
CONDITIONS AND RESULTS OF OPERATIONS

LIQUIDITY AND CAPITAL RESOURCES

The Company and its representatives from time to time make written or verbal forward looking statements, including statements contained in this and other filings with the Securities and Exchange Commission and in the Company's reports to stockholders, which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Such statements include, without limitation, the Company's expectations regarding sales, earnings or other future financial performance and liquidity, product introductions, entry into new geographic regions and general optimism about future operations or operating results. Although the Company believes that its expectations are based on reasonable assumptions within the bounds of its knowledge of its business and operations, there can be no assurance that actual results will not differ materially from its expectations. Factors that could cause actual results to differ from expectations include, without limitation:
(i) increased competitive activity from companies in the pharmaceutical industry, some of which have greater resources than the Company; (ii) social, political and economic risks to the Company's foreign operations, including changes in foreign investment and trade policies and regulations of the host countries and of the United States; (iii) changes in the laws, regulations and policies, including changes in accounting standards, that affect, or will affect, the Company in the United States and abroad; (iv) foreign currency fluctuations affecting the relative prices at which the Company and foreign competitors sell their products in the same market; and (v) the ability of the Company and third parties, including customers or suppliers, to adequately address Year 2000 issues. Additional information on factors that may affect the business and financial results of the Company can be found in filings of the Company with the Securities and Exchange Commission. All forward-looking statements should be considered in light of these risks and uncertainties. The Company assumes no responsibility to update forward-looking statements made herein or otherwise.

Cash and cash equivalents increased from $1,982,285 at December 31, 1999 to $5,501,774 at March 31, 2000. The Company received approximately $5.8 million from the exercise of outstanding options and warrants.

The Company has a worldwide, except for South Africa, license and supply agreement with Ares-Serono ("Serono") a Swiss pharmaceutical company. Under the terms of the agreement, as of March 31, 2000, the Company has earned $17 million in milestone payments and will continue to receive additional milestone payments. The Company supplies Crinone to Serono at a price equal to 30% of Serono's net selling price.

In connection with the 1989 purchase of the assets of Bio-Mimetics, Inc., which assets consisted of the patents underlying the Company's Bioadhesive Delivery System, other patent applications and related technology, the Company pays Bio-Mimetics, Inc. a royalty equal to two percent of the net sales of products based on the Bioadhesive Delivery System, to an aggregate of $7.5 million. The Company is required to prepay a portion of the remaining royalty obligation, in cash or stock at the option of the Company, if certain conditions are met. Through March 31, 2000, the Company has paid approximately $1.7 million in royalty payments.

In March 1999, the Company entered into a license and supply agreement with Mipharm SpA under which Mipharm SpA will be the exclusive marketer of the Company's previously

11

unlicensed women's healthcare products in Italy, Portugal, Greece and Ireland with a right of first refusal for Spain. Under the terms of the agreement, the Company received a $462,500 in 1999, net of expenses, upfront payment and expects to receive future milestone payments, as additional products are made available by the Company.

The Company believes that sales and liquidity will increase as Crinone is fully marketed by Ares-Serono.

As of March 31, 2000, the Company has outstanding exercisable options and warrants that, if exercised, would result in approximately $46.2 million of additional capital. However, there can be no assurance that such options or warrants will be exercised.

Significant expenditures anticipated by the Company in the near future are concentrated on research and development related to new products. The Company anticipates it will spend approximately $8.2 million on research and development in 2000 and an additional $100,000 on property and equipment.

As of March 31, 2000, the Company had available net operating loss carryforwards of approximately $51.2 million to offset its future U.S. taxable income.

In accordance with Statement of Financial Accounting Standards No. 109, as of March 31, 2000 and December 31, 1999, other assets in the accompanying consolidated balance sheets include deferred tax assets of approximately $18.6 million and $17 million, respectively, (comprised primarily of a net operating loss carryforward) for which a valuation allowance has been recorded since the realizability of the deferred tax assets are not determinable.

RESULTS OF OPERATIONS - THREE MONTHS ENDED MARCH 31, 2000 VERSUS THREE MONTHS ENDED MARCH 31, 1999

Net sales decreased by approximately $2.5 million to approximately $2,990,000 in 2000 as compared to approximately $5,466,000 in 1999. The decrease is primarily the result of decreased Crinone sales of approximately $1.9 million in 2000 from approximately $3,192,000 in 1999 to approximately $1,274,000 in 2000 as a result of Ares-Serono's transition to marketing Crinone in the U.S. and abroad.

Gross profit as a percentage of net sales decreased in 2000 to 59% as compared to 67% in 1999. The lower gross profit in 2000 is the result of the decrease in Crinone sales in which has a higher gross profit.

Selling and distribution expenses decreased by approximately $45,000 in 2000. Selling and distribution expenses decreased from approximately $858,000 in 1999 to approximately $813,000 in 2000 resulting from an approximately $400,000 decrease in U.S. over-the-counter product sales.

General and administrative expenses decreased by approximately $697,000 from approximately $1,485,000 in 1999 to approximately $788,000 in 2000. The majority of the decrease is the result of a decrease in legal expenses of approximately $518,000 related litigation settled in March 2000.

12

Research and development decreased in 2000 by approximately $27,000 from approximately $1,390,000 in 1999 to approximately $1,363,000 in 2000.

Net license fees of $387,500 in 1999 represent an upfront payment received in connection with a licensing agreement entered into in March 1999. No such fees were received in 2000.

Interest expense related to the convertible subordinated note payable totaled approximately $189,000 in 2000 and 1999.

In 1999, the Company recorded a $25,000 alternative minimum tax provision for U.S. federal taxes. No provision is required in 2000.

As a result, the net loss for the three months ended March 31, 2000 was $1,361,696 or $(.05) per common share as compared to a net income for the three months ended March 31, 1999 of $140,110 or $.00 per common share.

13

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

PART II - OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

The Company filed an action in the United States District Court for the Southern District of Florida ("Florida Action") in November 1997 seeking a declaratory judgment on certain issues related to its relationship with Lake Consumer Products, Inc. ("Lake") as governed in the contract between the Company and Lake. Lake filed an action against the Company in the United States District Court, Northern District of Illinois ("Illinois Action"), for damages alleged by Lake to have been suffered by it as a result of the FDA's allegations in July 1997 that the Company's nonoxynol-9 product, then marketed by Lake under the tradename Advantage 24, was not permitted to be sold under the monograph. The Illinois Action was dismissed by the Illinois Court and transferred to the Florida Court for consolidation as a counterclaim in the Florida Action. On March 16, 2000, the Company and Lake settled all outstanding issues in the consolidated Florida Action by the Company having bought out the contract for the sum of $1,200,000 ($600,000 in cash and $600,000 in the form of Company common stock). As a result, the Company reacquired the U.S. rights to the Advantage product and both parties agreed to have their legal actions dismissed.

Other claims and lawsuits have been filed against the Company. In the opinion of management and counsel, none of these lawsuits are material and they are all adequately reserved for or covered by insurance or, if not so covered, are without any or have little merit or involve such amounts that if disposed of unfavorably would not have a material adverse effect on the Company.

ITEM 2. CHANGES IN SECURITIES

None.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES

None.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

None.

ITEM 5. OTHER INFORMATION

ACQUISITION OR DISPOSITION OF ASSETS

Effective May 5, 2000, the Company sold various tangible and intangible assets related to the U.S. rights for Replens for a total of $4.5 million cash. Additionally, the purchaser agreed to buy up to $500,000 of Replens inventory from the Company and to pay future royalties of up to $2 million equal to 10% of future U.S. sales of Replens.

14

Additionally, effective May 5, 2000, the Company licensed its Legatrin PM, Legatrin GCM, Vaporizer in a Bottle and Diasorb brands to the same purchaser mentioned above. Under the terms of these agreements, the Company will receive license fees equal to 20% of the licensee's net sales of these brands. These agreements each have five-year terms with provisions for renewal and contain options that allow the licensee to acquire the brands from the Company.

FINANCIAL STATEMENTS OF BUSINESS ACQUIRED

Not Applicable

PRO FORMA FINANCIAL STATEMENTS

Unaudited Pro Forma Condensed Consolidated Financial Information of Columbia Laboratories, Inc. and Subsidiaries

The following unaudited pro forma condensed consolidated financial information is being filed herewith:

Unaudited Pro Forma Condensed Consolidated Balance Sheet at March 31, 2000

Unaudited Pro Forma Condensed Consolidated Statement of Income for the three months ended March 31, 2000

Unaudited Pro Forma Condensed Consolidated Statement of Income for the year ended December 31, 1999

Notes to Unaudited Pro Forma Condensed Consolidated Financial Information

15

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

UNAUDITED PRO FORMA CONDENSED CONSOLIDATED BALANCE SHEETS

                                                                                                  March 31, 2000
                                                                                -------------------------------------------------
                                                                                                  Pro Forma
                                                                                  Historical      Adjustments       Pro Forma (a)
                                                                                --------------   ------------      --------------
                                                                                 (Unaudited)
ASSETS
   Current assets-
      Cash and cash equivalents                                                 $    5,501,774   $  4,165,000 (b)  $    9,666,774
      Accounts receivable, net                                                       2,438,558        412,235 (c)       2,850,793
      Inventories                                                                    1,428,843       (412,235)(c)       1,016,608
      Prepaid expenses                                                                 407,254             --             407,254
      Other current assets                                                             311,442        (66,624)(d)         244,818
                                                                                --------------   ------------      --------------
         Total current assets                                                       10,087,871      4,098,376          14,186,247

   Property and equipment, net                                                         902,709             --             902,709
   Intangible assets, net                                                            5,955,088     (3,986,658)(e)       1,968,430
   Other assets                                                                        408,588             --             408,588
                                                                                --------------   ------------      --------------
   TOTAL ASSETS                                                                 $   17,354,256   $    111,718      $   17,465,974
                                                                                ==============   ============      ==============

LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIENCY)
   Current liabilities-
      Accounts payable                                                          $    1,492,949             --      $    1,492,949
      Accrued expenses                                                               1,072,250             --           1,072,250
      Deferred revenue                                                                 100,000             --             100,000
                                                                                --------------   ------------      --------------
         Total current liabilities                                                   2,665,199             --           2,665,199

      Convertible subordinated note payable                                         10,000,000             --          10,000,000
                                                                                --------------   ------------      --------------
         TOTAL LIABILITIES                                                          12,665,199             --          12,665,199
                                                                                --------------   ------------      --------------
    Stockholders' equity (deficiency)-
       Preferred stock, $.01 par value; 1,000,000 shares authorized:
          Series A Convertible Preferred Stock, 33
            shares issued and outstanding in 2000                                           --             --                  --
          Series B Convertible Preferred Stock, 1,630
            shares issued and outstanding in 2000                                           16             --                  16
          Series C Convertible Preferred Stock, 4,310
            shares issued and outstanding in 2000                                           43             --                  43
      Common stock, $.01 par value; 40,000,000 shares
          authorized; 30,412,641 shares
         issued and outstanding in 2000                                                304,126             --             304,126
      Capital in excess of par value                                               105,939,456         60,009 (f)     105,999,465
      Accumulated deficit                                                         (101,560,544)        51,709        (101,508,835)
      Accumulated other comprehensive income                                             5,960             --               5,960
                                                                                --------------   ------------      --------------
         TOTAL STOCKHOLDERS' EQUITY (DEFICIENCY)                                     4,689,057        111,718           4,800,775
                                                                                --------------   ------------      --------------
 TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIENCY)                        $   17,354,256   $    111,718      $   17,465,974
                                                                                ==============   ============      ==============

See accompanying notes to unaudited pro forma condensed consolidated financial information.

16

COLUMBIA LABORATORIES, INC. & SUBSIDIARIES
UNAUDITED PRO FORMA CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

                                               YEAR ENDED DECEMBER 31, 1999                 QUARTER ENDED MARCH 31, 2000
                                         ------------------------------------------  ------------------------------------------
                                                        PRO FORMA                                   PRO FORMA
                                          HISTORICAL   ADJUSTMENTS      PRO FORMA    HISTORICAL    ADJUSTMENTS      PRO FORMA
                                         ------------  ------------    ------------  ------------  ------------    ------------
NET SALES                                $18,921,074   ($5,547,259)(g) $13,373,815    $2,989,930   ($1,266,245)(g)  $1,723,685

COST OF GOODS SOLD                         5,655,350    (2,072,637)(h)   3,582,713     1,219,848      (555,005)(h)     664,843
                                         ------------  ------------    ------------  ------------  ------------    ------------
  Gross Profit                            13,265,724    (3,474,622)      9,791,102     1,770,082      (711,240)      1,058,842
                                         ------------  ------------    ------------  ------------  ------------    ------------
OPERATING EXPENSES:
  Selling and distribution                 3,938,756    (2,507,342)(i)   1,431,414       812,870      (439,005)(i)     373,865
  General and administrative               4,575,702      (588,151)(j)   3,987,551       788,128       (26,836)(j)     761,292
  Research and development                 6,652,096      (109,607)(k)   6,542,489     1,363,412       (48,175)(k)   1,315,237
                                         ------------  ------------    ------------  ------------  ------------    ------------
    Total operating expenses              15,166,554    (3,205,100)     11,961,454     2,964,410      (514,016)      2,450,394
                                         ------------  ------------    ------------  ------------  ------------    ------------
    Loss from operations                  (1,900,830)     (269,522)     (2,170,352)   (1,194,328)     (197,224)     (1,391,552)
                                         ------------  ------------    ------------  ------------  ------------    ------------
Other Income (Expense):
  License fees, net of expenses              462,500            --         462,500            --            --
  Interest income                            134,795            --         134,795        28,304            --          28,304
  Interest expense                          (755,352)           --        (755,352)     (188,838)           --        (188,838)
  Other, Net                                 (82,321)           --         (82,321)       (6,834)           --          (6,834)
                                         ------------  ------------    ------------  ------------  ------------    ------------
                                            (240,378)           --        (240,378)     (167,368)           --        (167,368)
                                         ------------  ------------    ------------  ------------  ------------    ------------
Income (loss) before income taxes         (2,141,208)     (269,522)     (2,410,730)   (1,361,696)     (197,224)     (1,558,920)
Provision for income taxes                    69,000            --          69,000            --            --              --
                                         ------------  ------------    ------------  ------------  ------------    ------------
Net Income/(Loss)                        ($2,210,208)    ($269,522)    ($2,479,730)  ($1,361,696)    ($197,224)    ($1,558,920)
                                         ============  ============    ============  ============  ============    ============
NET LOSS PER COMMON SHARE:
     Basic and Diluted                        ($0.09)       ($0.01)         ($0.10)       ($0.05)           --          ($0.05)
                                         ============  ============    ============  ============  ============    ============
WEIGHTED AVERAGE NUMBER
OF COMMON AND POTENTIAL
COMMON SHARES OUTSTANDING:
     Basic and Diluted                    28,853,000            --      28,853,000    29,527,163            --      29,527,163
                                         ============  ============    ============  ============  ============    ============

See accompanying notes to unaudited pro forma condensed consolidated financial information.

17

COLUMBIA LABORATORIES, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED PRO FORMA CONDENSED CONSOLIDATED FINANCIAL INFORMATION

(a) The unaudited pro forma condensed consolidated balance sheet gives retroactive effect to the sale and license of certain assets related to Columbia's over-the-counter products to Lil' Drug Store Products, Inc. ("Lil' Drug") as if the sale and license had occurred as of March 31, 2000. The unaudited pro forma condensed consolidated statements of income give retroactive effect as if the sale had occurred as of the beginning of the periods represented.

(b) Reflects the initial cash proceeds received by Columbia, net of expenses related to the transaction.

(c) Reflects inventory to be purchased by Lil' Drug.

(d) Reflects expenses of the transaction previously deferred.

(e) Reflects Replens trademark, net of accumulated amortization.

(f) Reflects stock warrants issued to Columbia's advisor on the transaction.

(g) Reflects revenues related to the over-the-counter products to be assumed by Lil' Drug, offset by royalty revenue from Lil' Drug as a result of the sale and license.

(h) Reflects cost of sales related to the over-the-counter products to be assumed by Lil' Drug.

(i) Reflects selling and distribution expenses related to the over-the-counter products to be assumed by Lil' Drug.

(j) Reflects general and administrative expenses related to the over-the-counter products to be assumed by Lil' Drug.

(k) Reflects research and development expenses related to the over-the-counter products to be assumed by Lil' Drug.

18

ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K

Exhibits

10.22 - Replens Purchase and License Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

10.23 - License Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

10.24 - Distribution Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

27.1 - Financial Data Schedule (for SEC use only)

Reports on Form 8-K

None.

19

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

COLUMBIA LABORATORIES, INC.

                                              /S/ DAVID L. WEINBERG
                                              ----------------------------------
                                              DAVID L. WEINBERG, Vice President-
                                              Finance and Administration,
                                              Chief Financial Officer

DATE:      MAY 15, 2000

20

INDEX TO EXHIBITS

EXHIBIT
NUMBERS

10.22 - Replens Purchase and License Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

10.23 - License Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

10.24 - Distribution Agreement dated April 18, 2000, between the Company and Lil' Drug Store Products, Inc.

27.1 - Financial Data Schedule (for SEC use only)


EXHIBIT 10.22

REPLENS PURCHASE AND LICENSE AGREEMENT

THIS AGREEMENT is made and entered into this 18th day of April, 2000, by and between COLUMBIA LABORATORIES, INC., a Delaware corporation having its principal place of business at 2875 N.E. 191 St., Suite 400, Aventura, Florida 33180 ("Seller"), and LIL' DRUG STORE PRODUCTS, INC., an Iowa corporation with its principal place of business at 1201 Continental Place NE, Cedar Rapids, Iowa ("Buyer").

RECITALS

WHEREAS, Seller is the owner of certain Technology, Patents and Trademarks (as hereinafter defined); and

WHEREAS, Seller desires to sell and license to Buyer, and Buyer desires to purchase and license from Seller, certain Technology, Patents and Trademarks for the Product (as hereinafter defined) in the Territory (as hereinafter defined) on the terms and subject to the conditions set forth herein.

NOW, THEREFORE, the parties agree as follows:

1. DEFINITIONS. As used in this Agreement, the following terms (except as otherwise expressly provided or unless the context otherwise requires) shall have the respective meanings set forth below (it being understood that the terms defined in this Agreement shall include the singular number in the plural and the plural number in the singular):

(a) "Affiliate" means any corporation or the business entity that either directly or indirectly controls a party to this Agreement, is controlled by such party, or is under common control of such party. As used herein, the term "controlling" means possession of the power to direct or cause the direction of the management and policies of a corporation or other entity, whether through the ownership of voting securities, by contract or otherwise.

(b) "Buyer Transaction Documents" means this Agreement and all other agreements or documents to be executed and delivered by Buyer pursuant to the requirements of this Agreement.

(c) "cGMP" means current good manufacturing practice regulations promulgated by the Federal Drug Administration ("FDA") and other regulatory agencies.

(d) "Columbia Patents" means the bioadhesive composition and method of treatment patent, U.S. Patent


No. 4,615,697 and the vaginal tissue moisturizing composition and method patent, U.S. Patent No. 5,474,768, and any and all patents issued pursuant thereto that are now used in connection with the Product.

(e) "Deferred Revenue" means the aggregate amount, as of the Closing Date (defined below), billed or received by Seller for the sale of the Product, the delivery of which will occur on or after the Closing Date.

(f) "Design Patents" means U.S. Design Patent Nos. 345,211 and 375,352, and any and all patents issued pursuant thereto that are now used in connection with the Product.

(g) "Encumbrance" means any encumbrance, security interest, mortgage, lien, pledge, claim, lease, right of first refusal, option, restrictive covenant, charge or other restriction or third party rights.

(h) "Field" means products that are promoted or marketed primarily as a vaginal moisturizer or vaginal lubricant. The Field does not include other products containing polycarbophil that are promoted or marketed primarily for a purpose outside the Field, but that may claim a side benefit of also being a vaginal moisturizer or lubricant.

(i) "Governmental Body" means any United States or other national, state, municipal or local government, domestic or foreign, any subdivision, agency, entity, commission or authority thereof, or any quasi-governmental or private body exercising any regulatory, taxing, importing or other governmental or quasi-governmental authority.

(j) "Intellectual Property Rights" means trade secrets, trademarks, trade names, logos, trade dress, graphics, designs and copyrights.

(k) "Net Sales" means the aggregate equivalent of gross sales received by Buyer, its Affiliates or sublicensees from or on account of the sale of the Product to non-affiliated third parties on which payments are due under this Agreement, less
(i) credits or allowances, if any, actually granted on account of cash or trade discounts,

2

recalls, rebates, rejection or return of the Product previously sold, and (ii) excises, sales taxes, value added taxes, consumptions taxes, duties or other taxes imposed upon and paid with respect to such sales (excluding income or franchise taxes of any kind). Net Sales shall not include any transfer between Buyer and any of its Affiliates or sublicensees for resale. No transfer of the Product for test or development purposes or as free samples shall be considered a sale hereunder for accounting and payment purposes. Net Sales shall be determined in accordance with generally accepted accounting principles ("GAAP").

(l) "Product" means the current formulation of Replens(R) brand vaginal moisturizer or lubricant and any and all improvements, reformulations or advances to such formulation in the Field.

(m) "Replens Patent" means the tissue moisturizing composition and method patent, U.S. Patent No. 5,968,500, and any and all patents issued pursuant thereto that are now used in connection with the Product.

(n) "Seller Transaction Documents" means this Agreement and all other agreements or documents to be executed by Seller pursuant to the requirements of this Agreement.

(o) "Transaction Documents" means the Buyer Transaction Documents and the Seller Transaction Documents, collectively.

(p) "Technology" means all pharmacological, toxicological, preclinical, clinical, technical and other information, data and analysis and know-how relating exclusively to the registration, manufacture, packaging, use, marketing and sale of the Product (including, without limitation, all words copyrighted by Seller) and all proprietary rights relating thereto owned by Seller or its Affiliates or to which Seller or its Affiliates has rights so as to be able to license, whether prior to or after the Closing Date, and relating or pertaining exclusively to the Product. Technology shall also include all improvements thereto from time to time developed or otherwise acquired by Seller as to which Seller has rights so as to be able to license such improvements.

3

(q) "Territory" means the United States of America and its territories.

(r) "Trademark" means the trademark "Replens" (Reg. No. 1,591,663).

(s) "Unit" means a single package of the Product, whether a three count, eight count, tube or other configuration.

2. TRANSFERRED ASSETS. On the Closing Date (as hereinafter defined), Buyer agrees to acquire from Seller and Seller agrees to convey, transfer and deliver to Buyer, free and clear of all Encumbrances, the Technology and Trademarks (the "Transferred Assets"), and fully paid, royalty free, transferable, perpetual, non-exclusive licenses of the Columbia Patents and the Design Patents in the Territory, with such licenses to be exclusive as to the Field (the "CP License" and the "Design License," respectively) to manufacture, produce, market, modify, sell, license or otherwise distribute the Product. The Transferred Assets include, but are not limited to:

(a) All tangible and intangible assets used by Seller exclusively in

(i) research and development pertaining to the Product;

(ii) the design of the Product and of different versions and packaging of the Product;

(iii) manufacture and reproduction of the Product and packaging;

(iv) modification of the Product; and

(v) marketing and distribution of the Product,

including all customer lists, manufacturing and sales contracts and quotations (including any open customer purchase orders), advertising and marketing material, including all sales collateral, sampling list, art work, web-sites, existing and under development, Product samples, manufacturing molds, trade names, clinical studies, customer support/inquiry material, historical production records, stability records, formulation information, records and all other relevant property.

(b) Ongoing support by Seller of Buyer's activities as discussed further herein, including without limitation regarding the following:

(i) assistance during transition after closing, pursuant to Section 6(a) of this Agreement;

(ii) coordination and sourcing of production of the Product, pursuant to Section 6(b) of this Agreement;

4

(iii) potential cross-branding of the Product with Seller's other products, pursuant to Section 6(d);

(iv) future Product line extensions, pursuant to Section 6(e);

(v) research and development for the Product line, pursuant to Section 6(e); and

(vi) handling and advice regarding regulatory matters, pursuant to Section 6(e).

This transaction also includes a transferable, non-exclusive license of the Replens Patent, with such license to be exclusive as to the Field (the "RP License") in the Territory to manufacture, produce, market, modify, sell, license or otherwise distribute the Product, for which Buyer shall pay Seller the License Fees described in Section 3 below.

It is agreed that except as set out expressly herein, Buyer is not assuming and shall not be liable for any debt, liability or obligation of Seller whatsoever, whether existing or contingent, direct or indirect, known or unknown. Without in any way limiting the generality of the foregoing, Buyer shall have no obligations with respect to any of the following liabilities:

(vii) Any liabilities of Seller occurring prior to the Closing Date under contracts, permits or licenses;

(viii) Any liabilities and/or obligations of Seller with respect to wages and salaries, bonuses, vacation pay, commissions, overtime, benefits, entitlement to severance whenever arising or occurring, with respect to any employees of Seller;

(ix) Any liabilities with respect to injury to or death of persons or damage to or destruction of property not constituting part of the Transferred Assets, including product liability claims and workers compensation claims arising out of the conduct of Seller prior to Closing, regardless of when said liability is asserted, including any liability for consequential or punitive damages in connection with the foregoing;

(x) Any liabilities for taxes payable by Seller;

(xi) Any trade or accounts payable, notes payable, loans, or other indebtedness or

5

obligations to make payments relating to the Transferred Assets.

3. CONSIDERATION. In consideration for the Transferred Assets and the Design License, Seller's express obligations hereunder, including but not limited to, Seller's obligations set out in Section 6 below, and any other rights granted to Buyer hereunder, Buyer shall pay to Seller the sum of $4,400,000 in cash at the Closing (as defined below), less any Deferred Revenue. In addition, in consideration for the CP License, Buyer shall pay to Seller the sum of $100,000 in cash at the Closing, and shall pay Seller, as consideration for the RP License, 10% of the Net Sales of the Product ("License Fees") from the Closing Date forward until such time as Buyer has paid Seller a total amount (the cash consideration paid at Closing and the License Fees paid) of $6,500,000 (calculated on a net present value basis assuming a 10% annual discount rate). Buyer may, in its sole discretion, pay all or any portion of the balance of the consideration described above at any time. Buyer shall pay Seller the License Fees for the first two (2) months within thirty
(30) days after the end of the second month following the Closing, and thereafter on a monthly basis within thirty (30) days after the close of each month. Each payment of the percent of Net Sales shall be accompanied by documentation evidencing the Net Sales for the previous period. At such time as Buyer shall have paid Seller the full amount of the consideration described above, Seller shall grant Buyer a perpetual, fully paid, royalty free, transferrable, non-exclusive license of the Replens Patents, with such license to be exclusive as to the Field.

4. CLOSING.

(a) CLOSING DATE. The transaction which is the subject of this Agreement shall be closed on or before May 5, 2000 ("Closing" and/or "Closing Date"), at the offices of Bradley & Riley PC, 2007 1st Avenue SE, Cedar Rapids, Iowa 52402, or at such time and place as the parties shall agree.

(b) DELIVERIES BY SELLER. At the Closing, Seller shall deliver the Transferred Assets and the CP License to Buyer by a Bill of Sale in the form acceptable to Seller and Buyer, appropriate assignment(s) of the Trademark, and any other documents reasonably necessary to complete this transaction.

(c) DELIVERIES BY BUYER. At Closing, Buyer shall deliver to Seller the cash consideration described in Section 3 above.

5. INVENTORY. In addition to the consideration set out in Section 3 above, Buyer agrees to purchase from Seller up to $500,000 worth of usable Product inventory (samples and Product prepared for sale, but excluding Replens 3) on an as needed basis during the six (6) month period beginning after the Closing Date. Buyer agrees to purchase from Seller inventory of the Replens 3 Product on an as needed basis. The Product inventory to be purchased by Buyer shall be selected by Buyer in its sole discretion. Initially, Buyer intends to use Seller's current outsource distribution partner, Redford Distributing, in Redford, Michigan. Buyer shall be responsible for the distribution/shipping fees for inventory shipped out of the Redford facility; provided,

6

however, if, within ninety (90) days after the Closing Date, Buyer elects to move the Product inventory to a Buyer designated warehouse for fulfillment, Seller and Buyer each shall bear one-half (1/2) of the costs of transportation of such Product inventory to such warehouse. The parties agree to work together in connection with the distribution and sale of such Inventory because the Inventory lists Seller as the manufacturer and provides Seller's 800 number for customer support. Buyer shall pay Seller for the Product inventory purchased within the first two (2) months after the Closing within thirty (30) days after the end of such second month following the Closing and thereafter on a monthly basis within thirty (30) days after the close of each month in which Buyer purchases Product inventory from Seller.

6. CONDUCT AFTER CLOSING.

(a) From and after the Closing Date, Seller will reasonably make available to Buyer all staff necessary to support the transition of the Product and the manufacturing and distribution of same, with such staff to include, but not be limited to, the Director of Sales, the Vice President of Research and Development, the Corporate Controller, and the Chairman and CEO. The parties anticipate the transition period will last at least ninety (90) days, and both Buyer and Seller agree to use their best efforts in the transition.

(b) Seller will continue to coordinate the production of the Product and act as a centralized sourcing point for same to insure Buyer does not face capacity restrictions in the manufacturing of the Product. Seller will designate an individual with Seller to work with Buyer on all supply matters. Buyer shall reimburse Seller for its costs of the Product (bill of materials multiplied by the amount of the Product, plus necessary freight/transportation charges) in U.S. dollars promptly upon Buyer's receipt and reasonable inspection of the Product. Seller will promptly notify Buyer of any increase in the cost of the Product or the freight/transportation charges. Seller and Buyer agree to work together to secure all necessary contracts to protect the supply of the Product and will work together to explore and qualify more cost effective methods of manufacture for producing the Product. Seller will, at Buyer's request, promote the manufacture of the Product in all facilities that Seller qualifies for production of its other current and future gel based products (Advantage S, Crinone, etc.). Seller will reasonably conduct its remaining business in such a way as not to interfere with the production of the Product by Buyer.

7

(c) Seller shall not sell or license for sale in the Territory any product in the Field, nor invest in, consult with, or in any manner assist any other person or entity to do same. Seller represents that as of the date hereof, it has not entered into any arrangement that would contravene the intentions of this paragraph.

(d) As of the Closing, Seller will not use the Trademark in the Territory on any exterior packaging or tubes or in any other manner that cross-brands the Product with any other products; provided, however, Seller may continue to market and sell the March production run of 100,000 Advantage S boxes and tubes that contain the Product name and the April production run of Advantage S with the Product name on the tube only. Notwithstanding the provisions hereof, at the expiration of six (6) months from the Closing, Seller shall stop selling all of its products that contain the Product name, whether on exterior packaging or on the product itself. At Buyer's request, Seller shall consider whether to cross-brand the Product with Seller's other products, on terms reasonably acceptable to both Buyer and Seller.

(e) Seller intends to work with Buyer on any future Product line extension and all research and development efforts for the Product line, at Buyer's request and at Buyer's cost, on terms and conditions to be agreed upon prior to such efforts. Seller shall also furnish such additional assistance as Buyer may reasonably request in connection with any regulatory compliance regarding the manufacture, marketing or sale of the Product in the Territory. Seller shall, at Buyer's request and at Buyer's cost, with respect to such regulatory matters, (i) act as liaison with the FDA or other governmental authority;
(ii) prepare and make all submissions regarding the regulatory matter; (iii) monitor all studies pertinent to the regulatory matter; and (iv) obtain regulatory approvals as reasonably deemed necessary by Seller and Buyer.

(f) Seller shall be responsible for any returns of the Product sold and shipped by Seller prior to the Closing Date ("Returns"). Buyer shall be entitled to a credit against the amount owed for License Fees pursuant to Section 3 above equal to the gross margin (net wholesale price less cost of goods sold) on such Returns, or equal to the amount of any refund paid by Buyer for any returns of

8

damaged Product. Damaged Product shall include, but is not limited to, Product with a retailer's inventory or pricing marking affixed. Notwithstanding the above, if Buyer sells any damaged Product after receiving a credit for such damaged Product, Buyer shall pay Seller of the Net Sales of such damaged Product, less any out-of-pocket expenses incurred by Buyer in such sale.

(g) To the extent Buyer, in its reasonable judgment, is required to honor any documented customer commitment, Seller will promptly reimburse Buyer for such commitment. Buyer shall provide Seller with all necessary financial records to verify such commitment. A documented customer commitment shall mean any written documentation related to financial or non-financial customer or broker commitments made by Seller related to the Products. Commitments may include customer or broker rebates, deductions, credits, allowances, promotional guarantees, bill backs and SPIFFS. Such documented customer commitments must clearly indicate that Seller and/or its representatives agreed to such commitment. If a customer or broker commitment is undocumented, Buyer and Seller agree to review such alleged commitment and, subject to Seller's approval, which approval shall not be unreasonably withheld, Seller will promptly reimburse Buyer for any commitment Buyer makes to honor such undocumented customer or broker commitment.

7. SELLER REPRESENTATIONS AND WARRANTIES. Seller represents and warrants to Buyer as follows:

(a) Seller is a corporation duly organized, existing and in good standing under the laws of Bermuda, with full right, power and authority to enter into and perform this Agreement and to grant all of the rights, powers and authorities herein granted.

(b) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Seller is a party, or Seller's articles of incorporation or bylaws.

(c) All manufacturing, production, marketing and sales agreements that are assigned hereby related to the Product are assignable to Buyer.

9

(d) This Agreement has been duly executed and delivered by Seller and is a legal, valid and binding obligation enforceable against Seller in accordance with its terms.

(e) Seller shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(f) Seller knows of no issued or pending patents, trademarks or patent or trademark applications relating to the Product that would prevent Buyer from using or selling the Product in the Territory.

(g) As of the Effective Date, there are no outstanding, pending or threatened violations, notice of noncompliance, warning letters, orders, injunctions, judgments or decrees of any court or government agency, investigations, claims, actions, suits, demands, administrative or other proceedings that have resulted or might result in the revocation, suspension or modification of any regulatory approval for the Product in the Territory.

(h) Seller ceased, as of March 13, 2000, all further sales of the Products to Quality King.

(i) Seller has conducted the sales of the Product consistent with its past practices and in the ordinary course of business from January 1, 2000 through the Closing Date.

(j) Seller is the sole and exclusive legal and equitable owner of the Transferred Assets, the Columbia Patents and the Replens Patent (and has good title to the tangible Transferred Assets) free and clear of any Encumbrances, other than certain royalty or other payments due from Seller to third parties in connection with the Columbia Patents and/or the Replens Patent. At Closing, Buyer shall acquire all of Seller's right, title and interest in the Transferred Assets, free and clear of all Encumbrances. Except for ordinary wear and tear, the Transferred Assets are in good operating condition and repair, free of known defects affecting operation, and are adequate and fit for the uses for which they are presently intended or being used. Seller has the right to transfer or license the Replens Patents, the Bioadhesive Patents and the Intellectual Property and no consent on the part of any other person

10

or entity is necessary to validate the transfer to Buyer of the Transferred Assets or the license to Buyer of the CP License or the RP License.

(k) All customer lists and all other information, reports and data made available or provided to Buyer by Seller are, in all material respects, true, correct and accurate as of the date provided or made available, as of the date of this Agreement, and as of the date of Closing. Seller has no knowledge of any intent of any such customer to modify or terminate its account or any of its outstanding orders.

(l) There is no action, suit, investigation, claim, arbitration or litigation pending or, to Seller's knowledge, threatened, against or involving the Transferred Assets or the propriety of this Agreement or any of the transactions contemplated hereby, at law or in equity, or before or by any court, arbitrator or governmental authority, and Seller is not operating under or subject to any order, judgment, decree, license or injunction of any court, arbitrator or governmental authority. No governmental agency or authority has at any time challenged, questioned, or commenced or given notice of intention to commence any investigation relating to, the legal right of Seller to conduct the operations of its business as it relates to the Product. Seller, and to Seller's knowledge each of its contract manufacturers in connection with the Product, has complied, and is in compliance, in all material respects with all laws, ordinances, regulations, awards, orders, judgments, decrees and injunctions applicable to the Transferred Assets, including all federal, state and local laws, ordinances, regulations and orders pertaining to employment or labor, safety, health, environmental protection, zoning and other matters. Seller has obtained and holds all permits, licenses and approvals (none of which has been modified or rescinded and all of which are in full force and effect) from all governmental authorities as they relate to the Product necessary in order to conduct its business and operations as presently conducted as it relates to the Product and to own, use and maintain the Transferred Assets, and has paid all regulatory fees and assessments attributable to Seller's business operations involving the Transferred Assets that are due or accrue prior to the Closing Date.

(m) All historical sales, costs of goods sold and operating expenses are substantially accurate and properly

11

classified on Seller's financial statements and on any other written information provided to Buyer by Seller in connection with this transaction.

(n) Seller's inventory of the Product at its outsource distribution partner's location in Redford, Michigan (other than its supply of Replens tubes) is sufficient to handle normal and customary sales of the Product after the Closing and represents at least a normal and customary three (3) month supply of the Product.

8. BUYER'S REPRESENTATIONS AND WARRANTIES. Buyer represents and warrants to Seller as follows:

(a) Buyer is a corporation duly organized, existing and in good standing under the laws of the State of Iowa, U.S.A., with full right, power and authority to enter into and perform this Agreement.

(b) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Buyer is a party, or Buyer's articles of organization or bylaws.

(c) This Agreement has been duly executed and delivered by Buyer and is a legal, valid and binding obligation enforceable against Buyer in accordance with its terms.

(d) Buyer shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(e) Buyer will actively market and sell the Product in the Territory, which may include use of samples, national media marketing plans, co-op advertising, trade shows, etc. Buyer will also timely provide quarterly sales and other marketing information usable to Seller in monitoring sales progress. Buyer will also maintain a qualified national force to sell/promote the Product.

(f) Buyer has or shall take all corporate action to effectuate the transactions contemplated by this Agreement and any other agreement or document executed in connection with this Agreement.

12

9. CONDITIONS PRECEDENT TO OBLIGATIONS OF BUYER. All obligations of Buyer to proceed with the Closing are subject to the fulfillment or waiver of each of the following conditions at or prior to Closing:

(a) Each and every representation and warranty of Seller shall be true and correct in all material respects when made and at the Closing.

(b) Seller shall have performed and complied in all material respects with all covenants and conditions required by this Agreement to be performed or complied with by it prior to or at the Closing.

(c) Any and all Encumbrances against the Transferred Assets shall have been released and any and all required consents shall have been obtained.

(d) All items to be delivered by Seller pursuant to Section 4 have been delivered.

If any of the conditions set forth in this Section 9 have not been fulfilled as of the Closing, Buyer may, at its option, by written notice to Seller, render its obligations hereunder null and void. By proceeding with the Closing, and unless otherwise agreed in writing, Buyer shall be conclusively deemed to have accepted or waived fulfillment of all of said conditions, but shall not be deemed to have waived the requirement that the representations and warranties of Seller shall survive the Closing.

10. COVENANTS AND AGREEMENTS OF SELLER.

(a) NEGATIVE COVENANTS. Seller further represents, covenants and agrees that it will not do or agree to do any of the following between the date of this Agreement and the Closing:

(i) Sell, assign, lease or otherwise transfer or dispose of any of the Transferred Assets.

(ii) Create, incur or permit any Encumbrance of any kind on the Transferred Assets now owned or hereafter acquired.

(iii) Enter into, engage in, or become a party to, directly or indirectly, any transaction with respect to the Transferred Assets other than in the ordinary course of business consistent with past practice.

13

(iv) Perform or omit to perform any act, which act or omission would cause Seller's warranties and representations in this Agreement to be untrue.

(b) AFFIRMATIVE COVENANTS. Seller further represents, covenants and agrees that between the date of this Agreement and the Closing it will:

(i) Provide Buyer and its representatives with full access during normal business hours to all of the properties, contracts, records, books, and accounts relating to the Transferred Assets and furnish Buyer and its representatives with such information relative to the Transferred Assets as Buyer or its representatives shall at any time, or from time to time, reasonably request.

(ii) Maintain its existing franchises and licenses relating to the Product, use its best efforts to preserve for Buyer relationships with suppliers, customers and others having business relations with Seller relating to the Product, and keep all Transferred Assets in their present condition, ordinary wear and tear excepted.

(iii) Maintain its books and records in the usual, regular and ordinary manner on a basis consistent with prior years, as they relate to the Product.

(iv) Subject to the terms and conditions of this Agreement, carry on the businesses and activities as they relate to the Product in the usual and ordinary course of business consistent with the past business practices.

(v) Maintain the validity of all permits and approvals relating to the Product and comply in all respects with all laws, rules, regulations and orders of any Governmental Body relating to the Product.

(vi) Take all corporate action necessary to effectuate the transactions contemplated by this Agreement and any other agreement or document executed in connection with this Agreement.

(vii) Upon receiving notice or otherwise

14

becoming aware of any violation under any statutes, rules, regulations or laws relating to the Product, promptly notify Buyer and, at Seller's discretion and expense, cure all such violations prior to the Closing Date.

11. CONDITIONS PRECEDENT TO OBLIGATIONS OF SELLER. The obligation of Seller to proceed with the Closing is subject to the fulfillment or waiver of each of the following conditions at or prior to Closing:

(a) Each and every representation and warranty of Buyer contained in the Buyer Transaction Documents shall be true and correct in all respects when made and at the Closing.

(b) Buyer shall have performed and complied in all material respects with all covenants and conditions required by this Agreement to be performed or complied with by it prior to or at Closing.

(c) No suit or action by any party or any investigation, inquiry or proceeding by any governmental authority or any legal or administrative proceeding that would have or be likely to have a material adverse effect on any of the Transferred Assets or on the business to be conducted by Buyer with the Transferred Assets following the Closing shall have been instituted or threatened on or before the Closing that:

(i) questions the validity or legality of this Agreement or any transaction contemplated hereby; or

(ii) seeks to enjoin any transaction contemplated hereby; or

(iii) seeks damages on account of the consummation of any transaction contemplated hereby.

(d) All items to be delivered by Buyer pursuant to Section 4 have been delivered.

If any of the conditions set forth in this Section 11 have not been fulfilled as of the Closing, Seller may, at its option, by written notice to Buyer, render its obligations hereunder null and void. By proceeding with the Closing, and unless otherwise agreed in writing, Seller shall be conclusively deemed to have accepted or waived fulfillment of all of said conditions.

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12. INDEMNIFICATION.

(a) Seller agrees to indemnify and hold harmless Buyer, its Affiliates and sublicensees and their respective employees, agents, officers and directors, successors and assigns, from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Buyer, its Affiliates or sublicensees arising out of or in connection with any (i) breach by Seller of any representation, warranty, covenant or obligation hereunder,
(ii) act or omission on the part of Seller or any of its employees or agents in the performance of this Agreement,
(iii) payments, commissions or fees of any kind due to consultants or brokers retained by Seller relating to the Product, and (iv) claim or demand of any kind for injury to a person or property arising from Seller's or its contract manufacturer's manufacturing, packaging or labeling of the Product; provided, that this indemnification shall not apply to the extent such claim or demand has resulted from changes in such manufacturing, packaging or labeling conducted by or at the direction of Buyer after Closing.

(b) Buyer agrees to indemnify and hold harmless Seller and its Affiliates and their respective employees, agents, officers and directors from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Seller or its Affiliates arising out of or in connection with any (A) breach by Buyer of any representation, warranty, covenant or obligation hereunder, (B) claim or demand of any kind for injury to person or property arising from Buyer's, its Affiliates' or sublicensee's manufacture, marketing, distribution and sale of the Product, provided, that this indemnification shall not apply to the extent such claim or demand has resulted from any negligent act or omission with respect to such Product by Seller, its Affiliates, their employees, agents or contract manufacturers, (C) act or omission on the part of Buyer or any of its employees or agents in the performance of this Agreement, (D) third party claims alleging infringement of such third parties' Intellectual Property Rights as a result of the advertisement, promotion or marketing materials created by or at the direction of Buyer, its Affiliates or sublicensees and used in connection with the sale of the Product hereunder, and (E) payments, commissions or fees

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of any kind due to consultants or brokers retained by Buyer relating to the Product.

(c) A party seeking indemnification under this Section 12 (the "Indemnified Party") must give prompt written notice thereof to the other party (the "Indemnifying Party"). The Indemnifying Party shall have the right to defend any such claim or demand subject to the right of the Indemnified Party to participate with counsel of its choice in such defense, but the fees and expenses of such additional counsel shall be at the expense of the Indemnified Party. The Indemnified Party shall cooperate fully in all respects with the Indemnifying Party in any such compromise, settlement or defense, including, without limitation, by making available all pertinent information and personnel under its control to the Indemnifying Party. The Indemnifying Party will not compromise or settle any claim or demand (other than, after consultation with Indemnified Party, a claim or demand to be settled by the payment of money damages and/or the granting of releases) without the prior written consent of the Indemnified Party, which consent shall not be unreasonably withheld.

(d) Each party shall maintain and keep in force for the term of this Agreement comprehensive general liability insurance including Products/Completed Operations, Contractual and Broad Form Property Damage covering its indemnification obligations hereunder with a minimum limit of Ten Million Dollars ($10,000,000) per annum combined single limit for Bodily Injury and Property Damage, to be increased as appropriate, consistent with prudent business practices prevailing in the business. Promptly after execution and delivery of this Agreement, each party shall furnish a certificate of insurance to the other party evidencing the foregoing endorsements, coverage and limits, and providing that such insurance shall not expire or be canceled or modified without at least thirty
(30) days prior notice to the other party.

(e) The representations and warranties of Seller and Buyer hereunder and their indemnification obligations shall survive the Closing.

13. RISK OF LOSS. The risk of loss or damage by fire or other casualty or cause to the Product inventory and any tangible assets included as part of the Transferred Assets until the Closing Date shall be upon Seller. In the event of such loss or damage prior to the Closing Date, Seller shall promptly restore, replace or repair the damaged Product inventory and/or tangible assets included as part of the Transferred Assets to their previous condition at Seller's sole cost and expense. If such loss or damage shall not be restored, replaced or repaired as of the Closing Date, Buyer shall, at its option, either:

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(a) Proceed with the Closing and receive all insurance proceeds to which Seller would be entitled as a result of such loss or damage; provided, however, that if such proceeds do not equal the loss, Seller shall pay the deficiency to Buyer; or

(b) Defer the Closing Date until such restorations, replacements or repairs are made (provided that no such deferral shall affect the rights of the parties hereto to terminate this Agreement pursuant to the provisions of Section 14).

14. TERMINATION. This Agreement may be terminated at any time prior to the Closing:

(a) by mutual consent of the parties hereto; or

(b) any party hereto:

(i) upon a material breach of this Agreement by the other party hereto;

(ii) if a court of competent jurisdiction or governmental authority shall have issued an order, decree or ruling or taken any other action (which order, decree or ruling the parties hereto shall use their best efforts to lift), in each case permanently restraining, enjoining or otherwise prohibiting the transactions contemplated by this Agreement, and such order, decree, ruling or other action shall have become final and nonappealable; or

(iii) if the Closing shall not have occurred on or before May 15, 2000; provided, however, that the right to terminate this Agreement shall not be available to any party whose breach of this Agreement has been the cause of, or resulted in, the failure of the transactions contemplated herein to occur on or before such date.

15. REMEDIES.

(a) DEFAULT BY BUYER. If Buyer shall default in the performance of its obligations under this Agreement in any material respect or if, as a result of Buyer's action or failure to act, the conditions precedent to Seller's

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obligation to close specified in Section 11 are not satisfied, and for such reason or reasons this Agreement is not consummated, and provided that Seller shall not then be in default in any material respect in the performance of Seller's obligations hereunder, Seller shall be entitled, by written notice to Buyer, to terminate this Agreement, and to pursue any other remedies Seller has at law or in equity or otherwise.

(b) DEFAULT BY SELLER. If Seller shall default in the performance of its obligations under this Agreement in any material respect, or if, as a result of Seller's action or failure to act, the conditions precedent to Buyer's obligation to close specified in Section 9 are not satisfied, and for such reason or reasons this Agreement is not consummated, and provided that Buyer shall not then be in default in any material respect in the performance of Buyer's obligations hereunder, Buyer shall be entitled by written notice to Seller, to terminate this Agreement, and to pursue any other remedies Buyer has at law or in equity or otherwise.

16. SPECIFIC PERFORMANCE. The parties acknowledge that the Transferred Assets to be delivered pursuant to this Agreement are unique and that no party hereto has an adequate remedy at law if the other party shall fail to perform any of its obligations hereunder, and all parties hereto therefore confirm and agree that the right of specific performance is essential to protect the rights and interests. Accordingly, in addition to any other remedies that any party hereto may have hereunder or at law or in equity or otherwise, the parties hereto hereby agree that Seller and Buyer shall each have the right to have all obligations, undertakings, agreements and other provisions of this Agreement specifically performed by the other and that each of them shall have the right to obtain an order or decree of such specific performance in any of the courts of the United States or of any state or other political subdivision thereof.

17. BROKERS. Seller shall be solely responsible for any brokerage fees, finders' fees, commissions or otherwise payable to any broker, finder or agent engaged by Seller in connection with the transactions contemplated by this Agreement. Buyer shall be solely responsible for any brokerage fees, finders' fees, commissions or otherwise payable to, any broker, finder or agent engaged by Buyer in connection with the transactions contemplated by this Agreement. Seller agrees to indemnify Buyer, and Buyer agrees to indemnify Seller, against any claims asserted against the other party for any fees or commissions due such person. Notwithstanding any other provision of this Agreement, this provision shall survive the Closing without limitation.

18. ARBITRATION.

(a) ARBITRATION. With the exception of any action for

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specific performance pursuant to Section 16, in the event of any dispute (a "Dispute") between the parties hereto subsequent to Closing with respect to the breach, interpretation or enforcement of this Agreement, such dispute shall be resolved by binding arbitration in accordance with the commercial arbitration rules of the American Arbitration Association ("AAA"). Notwithstanding the foregoing, the parties intend to depart from the AAA commercial arbitration rules to the extent any of the following provisions conflict with such rules.

(b) PANEL. Any arbitration shall take place before a panel of three (3) arbitrators (the "Panel"). The Panel shall be selected in accordance with the AAA's procedures for selecting an arbitration Panel, provided, that the Panel shall include one certified public accountant and one transactional lawyer, each of whom shall have had at least ten (10) years experience in his or her respective field, and at least three (3) years of arbitration experience. If any arbitrator on the Panel neglects or refuses to act or is or becomes incapable of acting, or dies before the Panel shall have made its award, and the parties fail to agree or concur in the appointment of another arbitrator, either party may serve on the other a notice in writing requiring him to agree and concur in the appointment of another arbitrator, and if such appointment is not made within twenty (20) days from the service of said notice, then the remaining arbitrators shall have power on the request in writing of either party to appoint another arbitrator who shall have the like authority to act in the arbitration and make an award and the like powers in all respects as if he had been appointed by the parties.

(c) BINDING EFFECT. Each of the parties agrees that the decision of the Panel shall be final and binding on the parties hereto and, provided diversity or other federal jurisdiction exists, the parties hereby consent to the entry of final judgment thereon in the United States District Court for the Southern District of New York, and to the issuance of execution on the judgment. The award may be appealed only to the court in which judgment on the award is required to be entered and only to the extent the award contains material errors of applicable law, is arbitrary or capricious, or was fraudulently obtained. If the parties cannot meet the applicable requirements for federal jurisdiction, the parties agree to the entry of judgment in the State Court of New York, and to the issuance of

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execution on such judgment. The parties hereto hereby consent to the jurisdiction of such court (i.e., such federal court, or, in the event federal jurisdiction does not exist, such state court) in reference to any matter arising out of the arbitration or this Agreement including but not limited to confirmation of any arbitration award and enforcement thereof by entry of judgment thereon or by any other legal remedy. As to any Dispute which under the terms hereof is made subject to arbitration, no suit at law or in equity based on such Dispute shall be instituted by either party hereto other than to enforce the award of the Panel. If any controversy shall arise after the award as to whether the award or any part thereof has been complied with, such controversy shall be determined by the same Panel.

(d) EVIDENCE. The Panel shall not be bound by strict rules of evidence and may give such right to evidence as may seem right and proper to it. The Panel shall schedule a pre-hearing conference to resolve procedural matters, arrange for the exchange of information, obtain stipulations, and narrow the issues. The parties will submit proposed discovery schedules to the Panel at the pre- hearing conference. The scope and duration of discovery will be within the sole discretion of the Panel. Unresolved discovery disputes may be brought to the attention of the chair of the arbitration panel and may be disposed of by the chair of the panel. The Panel shall have the discretion to order a pre-hearing exchange of information by the parties, including, without limitation, production of requested documents, exchange of summaries of testimony of proposed witnesses, and examination by deposition of parties and third-party witnesses. This discretion shall be exercised in favor of discovery reasonable under the circumstances. The arbitration shall be conducted in New York, New York. Any party may be represented by counsel or other authorized representative. In rendering a decision(s), the Panel shall determine the rights and obligations of the parties according to the substantive and procedural laws of New York and the terms and provisions of this Agreement. The Panel's decision shall be based on the evidence introduced at the hearing, including all logical and reasonable inferences therefrom. The Arbitrator may make any determination, and/or grant any remedy or relief that is just and equitable, subject to the express provisions of this Agreement. The Panel shall have power to award and direct that the parties or any of them shall execute such releases, conveyances,

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assurances, and do things as the Panel shall think fit and such releases, conveyances, assurances and things shall be executed and done accordingly. The Panel shall have the authority to proceed ex parte in case of the nonattendance of either of the parties or of their witnesses after thirty (30) days prior notice in writing by the Panel given to the parties respectively or their respective attorneys or agents notifying the time and place of meeting to proceed with the reference. Any provisional remedy that would be available from a court of law shall be available from the arbitrator to the parties to this Agreement pending arbitration.

(e) WAIVER OF CONSEQUENTIAL DAMAGES. The Panel shall have no authority to award consequential damages, punitive damages, and all other damages not measured by the prevailing party's actual damages, and each party hereby waives all claims to same. The Panel may not in any event make any ruling, finding or award that does not conform to the terms and conditions of the Agreement. Liabilities for Taxes are direct damages.

(f) DISCLOSURE. Except to the extent disclosure, filing, reporting or announcement thereof is required by law, including by any rules or regulations of any applicable governmental, regulatory or stock exchange agency or authority, neither a party nor an arbitrator may disclose the existence, content or results of any arbitration hereunder without the prior written consent of both parties, except to the extent that the recordation of a final judgment causes such matters to become public.

19. AUDITS. Until the full amount of the consideration set out in Section 3 above is paid to Seller, Buyer shall keep accurate records of all Product sales and other relevant data concerning the Product, and Buyer shall provide Seller reports thereof within thirty (30) days after the end of each quarter. Such reports shall state the number of Units of Product sold by Buyer, its Affiliates or sublicensees, if any, during the applicable period, as well as the number of free samples of the Product distributed and any Product returns made during such calendar quarter, together with an accounting of Net Sales with respect to such calendar quarter. Once a year, upon reasonable notice, at times mutually agreed upon and during business hours, Seller, at Seller's cost, may have the accounts of Buyer, its Affiliates or sublicensees for the preceding two (2) calendar years relating to the Product reviewed by an independent certified public accountant appointed by Seller and reasonably approved by Buyer, solely in order to verify amounts due under this Agreement. Seller and Buyer shall mutually determine a general strategy for such auditing in advance of its conduct. Such accountant shall not disclose to Seller any

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information except that which should properly be contained in a report required under this Agreement. Buyer shall promptly pay any underpayment evidenced by such audit, and Seller shall promptly refund any overpayment evidenced by such audit. If an audit evidences an underpayment of more than five percent (5%) with respect to the amounts actually paid, Buyer shall promptly pay such underpayment to Seller with interest at the prime rate as set by Citibank, from the time when such underpayment occurred, and shall reimburse Seller for the reasonable costs and expenses (including fees) of such audit.

20. RIGHT OF FIRST REFUSAL. Seller hereby grants Buyer a right of first refusal to purchase or license the Product for sale in other territories as such territories become available if such purchase or license requires only one total payment at the closing of such purchase or license. In all other cases, Seller hereby grants Buyer a right of first refusal to purchase or license the Product for sale in territories within NAFTA subject to Buyer providing evidence reasonably acceptable to Seller that Buyer can adequately market and sell the Product in the applicable territory or territories.

21. MISCELLANEOUS.

(a) NOTICES FROM BUYER. Any notices from Buyer to Seller hereunder shall be deemed sufficiently given upon delivery (with the return receipt, the delivery receipt, or the affidavit of messenger), refusal by addressee or notice to Buyer from the Post Office that such notice is undeliverable, if such notice has been mailed by United States registered or certified mail, postage prepaid, delivered by overnight courier or transmitted by facsimile transmission addressed to:

Columbia Laboratories, Inc. William J. Bologna, Chairman 2875 N.E. 191 St., Suite 400 Aventura, Florida 33180

with a copy (which shall not be deemed notice) to:

Lyon & Lyon, LLP
Scott H. Blackman
1701 Pennsylvania Avenue NW, Suite 1040 Washington, DC 20006

or at such other address or addresses as Seller may from time to time specify by notice in writing to Buyer, given in the manner provided in this Section.

(b) NOTICES FROM SELLER. Any notice from Seller to Buyer under this Agreement shall be deemed sufficiently given upon delivery (with the return receipt, the delivery receipt, or the affidavit of messenger), refusal by addressee or notice to Seller from the Post Office that such notice is

23

undeliverable, if such notice has been mailed by United States registered or certified mail, postage prepaid, delivered by overnight courier or transmitted by facsimile transmission addressed to:

Lil' Drug Store Products, Inc.
Chris DeWolf
1201 Continental Place NE
Cedar Rapids, IA 52402

with a copy (which shall not be deemed notice) to:

Bradley & Riley PC
Bradley G. Hart
2007 1st Avenue SE
PO Box 2804
Cedar Rapids, IA 52406-2804

or at such other address or addresses as Buyer may from time to time specify by notice in writing to Seller, giving in the manner provided in this Section.

(c) WAIVER; SEVERABILITY. No delay or failure on the part of any party hereto in exercising any right, power or privilege under any of the Transaction Documents or under any other instrument or document given in connection with or pursuant thereto shall impair any such right, power or privilege or be construed as a waiver of any default or any acquiescence therein. No single or partial exercise of any such right, power or privilege shall preclude the further exercise of such right, power or privilege, or the exercise of any other right, power or privilege. No waiver shall be valid against any party hereto unless made in writing and signed by the party against whom enforcement of such waiver is sought and then only to the extent expressly specified therein. The unenforceability or invalidity of any provision of any of the Transfer Documents shall not affect the enforceability or validity of any other provision.

(d) BENEFIT AND ASSIGNMENT. No party hereto shall assign this Agreement, in whole or in part, whether by operation of law or otherwise, without the prior written consent of the other party hereto, and any purported assignment contrary to the terms hereof shall be null, void and of no force and effect.

(e) CONFIDENTIALITY. Except to the extent disclosure, filing, reporting or announcement of this Agreement is

24

required by law, including by any rules or regulations of any applicable governmental, regulatory or stock exchange agency or authority, the existence and substance of this Agreement shall remain confidential for a period of ten (10) days following the date hereof. If the transaction that is the subject of this Agreement is not consummated, Buyer agrees that it will return to Seller, and Seller agrees that it will return to Buyer, all records and other documents of the other then in that party's possession and will not itself use, or disclose, directly or indirectly, to any person any Confidential information with respect to the other party or the business learned by that party during the period between the date hereof and termination of this Agreement. The term "Confidential Information" as used herein means all information of a business or technical nature, including, but not limited to, all patents and technology, relevant to each party's business that is not publically known. The foregoing provisions shall survive the Closing or any termination of this Agreement without limitation.

(f) ENTIRE AGREEMENT. Any schedules and exhibits attached to this Agreement are incorporated herein by reference. This Agreement sets forth the entire understanding of the parties with respect to the subject matter hereto, supersedes all prior oral or written agreements, instruments and understandings with respect to such matters, and may be modified only by instruments signed by Seller and Buyer.

(g) COUNTERPARTS. This Agreement may be executed simultaneously in one or more counterparts, each of which shall be deemed an original but all of which together shall constitute one and the same instrument.

(h) EXPENSES. Seller and Buyer shall each pay its own legal and accounting costs and other expenses incurred in negotiating and preparing this Agreement and in closing and carrying out the transactions contemplated by this Agreement.

(i) GOVERNING LAW. This Agreement, the rights and obligations of the parties hereto, and any claims or disputes relating hereto, shall be construed and governed in accordance with the laws of the State of New York, excluding the choice of law rules thereof.

(j) HEADINGS. The subject headings of Sections of this

25

Agreement are included for purposes of convenience only and shall not affect the construction or interpretation of any of its provisions.

(k) FURTHER ASSURANCES. Each party hereto shall cooperate, shall take such further action and shall execute and deliver such further documents at any time prior to at or after the Closing as may be reasonably requested by any other party in order to carry out the provisions and purposes of this Agreement, including but not limited to the endorsement of checks received after Closing in payment of the receivables being purchased by Buyer.

(l) RELEASE OF INFORMATION. Neither party shall disclose any of the terms of the transactions contemplated by this Agreement, except as may be required by law, and the contents of any press releases concerning the transactions contemplated by this Agreement shall be determined by mutual agreement of the parties. The foregoing provisions shall survive the Closing or any termination of this Agreement without limitation.

(m) FACSIMILE SIGNATURES. For purposes of executing this Agreement, a facsimile signature shall be deemed as effective as an actual signature.

(n) REMEDIES CUMULATIVE. Except as specifically provided herein, the remedies provided herein shall be cumulative and shall not preclude the assertion by Seller or by Buyer of any other rights or the seeking of any other remedies against the other parties, or their successors or assigns.

IN WITNESS WHEREOF, the parties have duly executed and delivered this Agreement effective as of the date first above written.

COLUMBIA LABORATORIES, INC.

By:/S/ WILLIAM J. BOLOGNA
   -------------------------------
   William J. Bologna, Chairman of the Board

LIL' DRUG STORE PRODUCTS, INC.

By:/S/ DENNIS L. OLDORF
   -------------------------------
   Dennis L. Oldorf, Chairman of the Board

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LICENSE AGREEMENT

This License Agreement (the "Agreement") is made and entered into as of this 18th day of April, 2000 by and between Columbia Laboratories, Inc., a Delaware corporation having its principal place of business at 2875 N.E. 191 St., Suite 400, Aventura, Florida 33180 ("Licensor"), and Lil' Drug Store Products, Inc., an Iowa corporation with its principal place of business at 1201 Continental Place NE, Cedar Rapids, Iowa 52402 ("Licensee");

WITNESSETH:

WHEREAS, Licensor is the owner and has the right to grant licenses with respect to certain Technology, Patents and the Trademarks (as hereinafter defined); and

WHEREAS, Licensor wishes to grant to Licensee an exclusive license to the Technology, Patents and the Trademarks for the manufacture, use and sale of the Products (as hereinafter defined) in the Territory (as hereinafter defined), and Licensee wishes to receive such a license, on the terms and subject to the conditions set forth herein;

NOW, THEREFORE, for and in consideration of the mutual promises and covenants herein contained, the parties hereto agree as follows.

1. DEFINITIONS. As used in this Agreement, the following terms (except as otherwise expressly provided or unless the context otherwise requires) shall have the respective meanings set forth below (it being understood that the terms defined in this Agreement shall include the singular number in the plural, and the plural number in the singular):

(a) "Affiliate" shall mean any corporation or other business entity that either directly or indirectly controls a party to this Agreement, is controlled by such party, or is under common control of such party. As used herein, the term "control" means possession of the power to direct or cause the direction of the management and policies of a corporation or other entity, whether through the ownership of voting securities, by contract or otherwise.

(b) "cGMP" shall mean current good manufacturing practice regulations promulgated by the FDA and other regulatory agencies.

(c) "Confidential Information" shall mean all information and/or technical data that is disclosed by one party hereto to the other party hereto pursuant to this


Agreement, whether written or oral, that the disclosing party treats as confidential and identifies as such (by marking written information "Confidential" and if oral, by promptly reducing it to writing and marking it "Confidential"), other than (i) information known to the receiving party or its Affiliates prior to the disclosure of such information to such party, provided said prior knowledge is supportable by documentary evidence, (ii) information which at the time of the disclosure is generally known to the public, provided that such public knowledge does not result from any act or disclosure by the receiving party or one of its Affiliates in violation of the terms of this Agreement or of any other confidentiality obligation owed to the disclosing party, (iii) information that can be shown to be independently discovered, after the date hereof, by a party, or one of its Affiliates, without the aid, application or use of the disclosed information, or (iv) information obtained by the receiving party from a third party that is determined to be in lawful possession of such information, provided such third party is not in violation of any contractual or legal obligation to the disclosing party or one of its Affiliates with respect to such information.

(d) "Effective Date" shall mean the date May 5, 2000.

(e) "Field" shall mean the present formulations of Vaporizer in a Bottle(R) brand cough and cold product, Advanced Formula Legatrin P.M.(R) brand sleep-aid analgesic and Legatrin GCM(R) brand nutritional, and their generic equivalents.

(f) "Intellectual Property Rights" shall mean trade secrets, trademarks, trade names, logos, trade dress, graphics, designs, patents, copyrights or other proprietary rights used by Licensor in connection with the Products.

(g) "Net Sales" shall mean the aggregate equivalent of gross sales received by Licensee, its Affiliates or sublicensees from or on account of the sale of the Products to non-affiliated third parties on which payments are due under this Agreement, less
(i) credits or allowances, if any, actually granted on account of cash or trade discounts, recalls, rebates, rejection or return of the Products previously sold, and (ii) excises, sales taxes, value added taxes, consumptions taxes, duties or other taxes imposed upon and paid with respect to such sales (excluding income or franchise taxes of any kind). Net Sales shall not include any transfer between Licensee and any of its Affiliates or sublicensees for resale. No transfer of the Products for test or development purposes or as free samples shall be considered a sale

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hereunder for accounting and payment purposes. Net Sales shall be determined in accordance with generally accepted accounting principles ("GAAP").

(h) "Patents" shall mean the patents filed in the Territory owned by the Licensor or its Affiliates or with respect to which Licensor or its Affiliates have the right to grant licenses in the Territory, the claims of which may be infringed, absent a license, by the manufacture, use or sale of the Products within the Territory, i.e. U.S. Patent No. 4,742,960.

(i) "Products" shall mean the current formulations of Advanced Formula Legatrin P.M./Registered trademark/ brand sleep-aid analgesic, Legatrin GCM/Registered trademark/ brand nutritional, and Vaporizer in a Bottle/Registered trademark/ brand cough and cold product, and any and all improvements, reformulations or advances to the existing formulations.

(j) "Technology" shall mean all pharmacological, toxicological, preclinical, clinical, technical and other information, data and analysis and know-how relating to the registration, manufacture, packaging, use, marketing and sale of the Products (including, without limitation, all words copyrighted by Licensor) and all proprietary rights relating thereto owned by Licensor or its Affiliates or to which Licensor or its Affiliates has rights so as to be able to license, whether prior to or after the Effective Date, and relating or pertaining to the Products.

(k) "Territory" shall mean the United States of America and its territories.

(l) "Trademarks" shall mean the United States trademarks "Advanced Formula Legatrin P.M." (Reg. No. 1,973,493), "Legatrin GCM" (Serial No. 75/793300), "Vaporizer in a Bottle" (Reg. No. 1,000,400), and any variations thereof.

(m) "Unit" shall mean a single item package of any of the Products.

2. GRANT OF LICENSE.

(a) Licensor grants to Licensee, and Licensee accepts from Licensor, on the terms and conditions stated herein, an exclusive (even as to Licensor and Licensor's Affiliates) right and license, with the right to sublicense, under the Patents and Technology, only to manufacture, produce, market, distribute, use and sell the Products in the Territory; provided, however that Licensee will only

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sublicense the Products with Licensor's prior written approval, which approval shall not be unreasonably withheld.

(b) Licensor grants to Licensee, and Licensee accepts from Licensor, on the terms and conditions contained herein an exclusive right and license, with the right to sublicense, to use the Trademarks in the manufacture, distribution, advertising, marketing, use and sale of the Products (and any line extension to the Products as to which Licensee has obtained Licensor's prior written consent, not to be unreasonably withheld) only in the Territory. Neither Licensor or Licensee shall use, nor permit any of its Affiliates or other licensees to use, the Trademarks or any similar marks on any other product marketed, used or sold in the Territory without the prior written consent of the other party hereto. Licensee shall not use, nor permit any of its Affiliates or any other licensees to use, the Trademarks or any similar marks outside the Territory.

(c) Licensee may at any time request from Licensor, and Licensor agrees to grant directly to any party in the Territory exclusive license rights consistent with those granted to Licensee herein. Accordingly, upon receipt of Licensee's request, Licensor shall enter into and sign a separate direct license agreement or agreements with the companies designated by Licensee in the request. All direct agreements shall be prepared by Licensee. In the absence or upon the expiration of laws and regulations to the contrary, the terms and conditions thereof shall not be less favorable to Licensor than those contained in this Agreement and shall be similar to the terms and conditions contained in this Agreement. Such licenses and agreements, and the party to whom they are granted, must be approved by Licensor, which approval shall not be unreasonably withheld.

(d) To the extent reasonable and necessary for Licensee to fulfill its obligations hereunder, Licensor shall transfer or grant Licensee the rights to use Licensor's art work, customer lists, records, web-sites, contracts, advertising/media schedules in connection with the manufacturing, production, use or sale of the Products in the Territory.

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3. LICENSE FEES. In consideration of the license and other rights granted to Licensee hereunder, Licensee shall pay to Licensor twenty percent (20%) of the Net Sales of the Products during the term hereof, with such fees to be paid to Licensor within (thirty) 30 days after the end of the second month following the Effective Date, and thereafter on a monthly basis within thirty (30) days after the close of each month. Each payment of license fee shall be accompanied by documentation evidencing the Net Sales for the previous period.

4. MANUFACTURE AND DISTRIBUTION.

(a) Licensor shall assign all contracts or agreements with suppliers, wholesalers, manufacturers, distributors and retailers in connection with the manufacture, production, sale and distribution exclusively of the Products during the term hereof (including any open customer purchase orders), and Licensee shall assume responsibility for the same. In addition, Licensor shall transfer, assign or license to Licensee all necessary rights to the Products, Intellectual Property and Technology reasonably necessary for Licensee to assume such responsibility; provided, however, in no event shall Licensee be responsible for any royalty, license or other similar fees or payments to third parties required in connection with the rights to the Products, Intellectual Property or Technology. Licensor shall reasonably make available to Licensee all staff necessary to facilitate the transition of the manufacturing and production of the Products, with such staff to include, but not be limited to, the Director of Sales, the Vice President of Research and Development, the Corporate Controller, and the Chairman and CEO. The transition period is anticipated to last sixty (60) days. Licensee and Licensor each agree to use their commercially reasonable best efforts to facilitate the transition.

(b) During the term of the Agreement, Licensor shall not sell or license for sale in the Territory any product in the Field. Licensor represents that as of the Effective Date it has not entered into any arrangement that would contravene the intentions of this paragraph.

(c) As may be required for regulatory purposes, Licensee grants Licensor the right to refer to, and shall cause its contract supplier to grant to Licensor access to,

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contract supplier's master file relating to the Products and undertakes to notify Licensor and provide Licensor with details of any changes to said master file or other filings by the contract supplier with the regulatory authorities relative to the Products. Licensee shall obtain Licensor's consent before it or its contract supplier makes any material change in any manufacturing process for the Products, which consent shall not be unreasonably withheld.

(d) Upon reasonable prior written notice given by Licensor to Licensee, Licensee shall permit and shall cause its contract supplier to permit representatives of Licensor or designees of Licensor acceptable to Licensee and/or contract supplier, to inspect any manufacturing, quality control or testing facilities used by or in connection with the manufacture or testing of the Products and annual cGMP audits provided that such representatives or designees of Licensor shall conduct such inspections in a manner that shall reasonably cause the least possible interruption to Licensee's or the contract supplier's operations under the particular circumstances. Such inspection shall take place in a timely manner and shall be permitted to take place during any or all phases of manufacturing, quality control and testing, and shall provide for Licensee and/or the contract supplier's granting to Licensor access to information in its possession relevant to determining whether cGMP and Licensor's quality standards in effect as of the Effective Date are being met and are likely to be met with respect to manufacture of the Products.

(e) Personnel of Licensor or Licensor's designee shall be entitled to witness the manufacturing of test batches, scale-up batches and full-size production batches.

(f) All Products manufactured and supplied hereunder shall meet the quality control specifications and the specifications in the applicable regulatory filing through the expiration date stated on that Product package, as reasonably determined by Licensor. Such Products shall also not be adulterated or misbranded within the meaning of the U.S. Food, Drug and Cosmetic Act, as amended.

(g) Licensor agrees that the manufacturers and manufacturing processes currently used by Licensor in the manufacture of the Products, if continued by Licensee, shall meet all of the requirements set out in this Section 4.

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(h) Licensee shall have the right to purchase from Licensor the Product inventory (samples and Product prepared for sale) on an as needed basis for a six month period beginning after the Effective Date. The Product inventory to be purchased by Licensee shall be selected by Licensee in its sole discretion. Initially, Licensee intends to use Licensor's current outsource distribution partner, Redford Distributing in Redford, Michigan. Licensee shall be responsible for the distribution/shipping fees for inventory shipped out of the Redford facility; provided, however, if, within ninety (90) days after the Effective Date, Licensee elects to move the Product inventory to a Licensee designated warehouse for fulfillment, Licensor and Licensee shall each bear one-half (1/2) the costs of transportation of such Product inventory to such warehouse. The parties agree to work together in connection with the distribution and sale of such inventory because the inventory lists Licensor as the manufacturer. Licensee shall pay Licensor for the Product inventory purchased within the first two months after the Effective Date within thirty (30) days after the end of such second month following the Effective Date and thereafter on a monthly basis within thirty (30) days after the close of each month in which Licensee purchases Product inventory from Licensor.

5. RETURNS AND CUSTOMER COMMITMENTS. Licensor shall be responsible for any returns of Products sold and shipped by Licensor prior to the Effective Date ("Returns"). Licensee shall be entitled to a credit against the next license fees due hereunder for Returns as follows: (i) a credit equal to the gross margin (net wholesale price less cost of goods sold) on such Returns; or (ii) a credit equal to the amount of any refund paid by Licensee for any Returns of expired or damaged Products. Expired Products shall mean Units of (i) Legatrin P.M. that have twelve
(12) months or less before their expiration date; (ii) Legatrin GCM that have eighteen (18) months or less before their expiration date; and (iii) Vaporizer in a Bottle that have less than twenty-four (24) months or less before their expiration date. Damaged Products shall include, but are not limited to, those Products with a retailer's inventory or pricing marking affixed. Notwithstanding the above, if Licensee sells any expired Product after receiving a credit for such returned Product, Licensee shall pay Licensor the Net Sales of such returned Product, less any out-of-pocket expenses incurred by Licensee in such sale.

To the extent Licensee, in its reasonable judgment, is required to honor any documented customer commitment, Licensor will promptly reimburse Licensee for such commitment. Licensee shall provide Licensor with all necessary financial records to verify such commitment. A documented customer commitment shall mean any written documentation related to financial or non-financial customer or broker commitments made by Licensor related to the Products. Commitments may include customer or broker rebates, deductions, credits, allowances, promotional guarantees, bill backs and SPIFFS. Such documented customer commitments must clearly indicate that Licensor and/or its representatives agreed to such commitment. If a customer or broker commitment is undocumented, Licensee and Licensor agree to review such alleged commitment and, subject to Licensor's approval, which approval shall not be unreasonably withheld, Licensor will promptly reimburse Licensee for any commitment Licensee makes to honor such undocumented customer or broker commitment.

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6. MARKETING.

(a) Licensee will be responsible for actively marketing and selling the Products (Vaporizer in a Bottle/Registered trademark/ brand cough and cold product and Advanced Formula Legatrin P.M./Registered trademark/ brand sleep-aid analgesic only) in the Territory, which may include use of samples, national media marketing plans, coop advertising, trade shows, etc., and Licensor may, at its option, participate in or support such marketing efforts. Licensee will use reasonable efforts to market and sell Legatrin GCM/Registered trademark/ brand nutritional.

(b) Licensee will timely provide quarterly sales and other marketing information useful to Licensor in monitoring sales progress.

(c) Licensor shall notify Licensee prior to Licensor communicating with any regulatory authorities with respect to the Products. Licensee shall promptly disclose and refer to Licensor any regulatory action or inquiry concerning the Products.

(d) Licensee will maintain a qualified, national sales force to sell/promote the Product.

7. MAINTENANCE OF PATENTS AND TRADEMARKS.

(a) Licensor and Licensee expressly acknowledge that Licensor does not intend to further develop the Patents, Trademarks or Technology for the Products. However, Licensor shall keep Licensee currently advised of the status of the Patents, the Trademarks and/or Technology. Licensor shall bear all costs for the maintenance of the Patents and Trademarks. If Licensor fails to carry out such obligations set forth in this Section 7, Licensee may, in its sole discretion, carry out such maintenance on Licensor's behalf and may set off such cost against amounts due to Licensor hereunder, provided that such action by Licensee is commercially reasonable.

(b) Trademark Use and Quality Control

(i) Licensee agrees to use the Trademarks in accordance with good customary trademark practice, and to avoid taking any action that would

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in any manner impair or detract from the value of the Trademarks, or the goodwill and reputation of Licensor; provided, however, Licensee may modify and/or redesign the labels and other packaging of the Products with Licensor's prior written approval, which approval shall not be unreasonably withheld. Licensee acknowledges Licensor's ownership of the Trademarks and related goodwill.

(ii) Licensee agrees to use the Trademarks only in the form and manner and with appropriate legends as approved from time to time by Licensor, and not to use or allow use of any other trademark or service mark in combination with the Trademarks without the prior written approval of Licensor, provided that such approval shall be granted unless Licensor reasonably objects.

8. INFRINGEMENT OF PATENTS, TECHNOLOGY AND/OR TRADEMARKS.

(a) Licensee and Licensor shall each promptly notify the other following the discovery of any alleged infringement or unauthorized use of the Patents, Technology and/or Trademarks that may come to their attention. Licensor shall promptly undertake, at Licensor's expense, commercially reasonable efforts to obtain a discontinuance of the infringement or unauthorized use and, if not successful, Licensor may, at its sole option, bring suit against such infringer.

(b) If Licensor fails to obtain a discontinuance of such infringement and/or elects not to bring an infringement suit, then Licensor shall give notice in writing to Licensee within thirty (30) days of such failure or election and Licensee may, but is not required to, obtain a discontinuance of the alleged infringement or unauthorized use or bring an infringement suit; provided, that without the prior written consent of Licensor, Licensee shall not agree to any settlement with respect to such infringement or unauthorized use that compromises the value of the license granted hereunder. Any infringement suit by Licensee shall be in the name of Licensee, or in the name of Licensor, or jointly by both Licensee or Licensor, as may be required by the law of the forum or as may be reasonably requested by Licensor to protect its interests.

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Licensor shall execute such documentation as may be reasonably required by Licensee with respect to such suit.

(c) It is understood and agreed that the party to this Agreement that institutes suit shall bear solely all costs and expenses in connection therewith and shall be entitled to recover all costs first and then the balance of any sums received, obtained, collected or recovered, whether by judgment, settlement or otherwise as a result of such suit, shall be paid to Licensor and/or Licensee to cover their respective damages, with any balance to be divided 50% to Licensee and 50% to Licensor; provided, however, that if a settlement by Licensee (with the prior written consent of Licensor to the extent required above) includes the granting by Licensee of rights hereunder to a third party, amounts received by Licensee from such settlement shall not be shared with Licensor and sales of the Products by such third party pursuant to such rights shall not be included in Net Sales. In addition, with respect to any suit for infringement or unauthorized use of the Patents, Technology and/or Trademarks, the party that did not institute suit shall render all reasonable assistance to the party that did institute suit at the latter's expense, including, but not limited to, executing all documents as may be reasonably requested by the party that did institute the suit. The party that did institute suit shall keep the other party informed of, and shall promptly consult with the other party regarding, the status of any such suit and shall provide the other party with copies of all pleadings filed in such suit.

9. INFRINGEMENT OF THIRD-PARTY INTELLECTUAL PROPERTY RIGHTS.

(a) Each party hereto shall notify the other promptly of the receipt of notice of any action, suit or claim alleging infringement by the Patents, the Technology, the Trademarks or the Products of any intellectual property rights of a third party.

(b) In no event shall either party settle any such allegation of infringement without the prior written consent of the other, which consent shall not be unreasonably withheld or delayed. If any such settlement requires Licensee to make royalty or other payments to a third party in order for Licensee to make, have made, use

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or sell or to continue making, having made, using or selling the Products in the Territory, Licensee shall be entitled to offset such amounts so paid to any third party against any amounts that may thereafter become due to Licensor under this Agreement.

10. CONFIDENTIALITY. Each party hereto shall hold all Confidential Information in confidence, use it only in connection with the performance of its obligations pursuant to this Agreement and use its diligent effects (consistent with those it uses to safeguard its own confidential information) to safeguard Confidential Information and to prevent the unauthorized use or disclosure of any Confidential Information. Each party hereto shall ensure that its Affiliates or employees who have access to any Confidential Information shall be made aware of and subject to these obligations. The receiving party may disclose Confidential Information to regulatory authorities for the purpose of seeking marketing approval of the Products pursuant to this Agreement and may also disclose Confidential Information to individuals who have a need to know to effectuate the development and commercialization of the Products pursuant to this Agreement, provided such individual is bound by a confidentiality obligation comparable to the obligation set forth in this Section 10. The obligations of the parties hereto under this Section 10 shall survive the expiration or termination of this Agreement.

11. REPRESENTATIONS, WARRANTIES AND COVENANTS AND INDEMNIFICATION.

(a) Licensor hereby represents, warrants and covenants the following:

(i) Licensor is a corporation duly organized, existing and in good standing under the laws of Delaware, with full right, power and authority to enter into and perform this Agreement and to grant all of the rights, powers and authorities herein granted.

(ii) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Licensor is a party, or Licensor's articles of incorporation or bylaws.

(iii) All manufacturing, production, marketing and sales agreements that are assigned hereby related to the Products, are assignable to Licensee.

(iv) This Agreement has been duly executed and delivered by Licensor and is a legal, valid and

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binding obligation enforceable against Licensor in accordance with its terms.

(v) Licensor shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(vi) As of the Effective Date, Licensor knows of no issued or pending patents, trademarks or patent or trademark applications relating to the Products that would prevent Licensee from using or selling the Products in the Territory.

(vii) As of the Effective Date, there are no outstanding, pending or threatened product liability or breach of warranty or other similar claims, actions, suits, demands, investigations, arbitrations, administrative or other proceedings, or orders, injunctions, judgments or decrees of any court or government agency in connection with the Products in the Territory.

(viii) As of the Effective Date, there are no outstanding, pending or threatened violations, notice of noncompliance, warning letters, orders, injunctions, judgments or decrees of any court or government agency, investigations, claims, actions, suits, demands, administrative or other proceedings that have resulted or might result in the revocation, suspension or modification of any regulatory approval for the Products in the Territory.

(ix) Licensor ceased, as of March 13, 2000, all further sales of the Products to Quality King.

(x) Licensor has conducted the sales of the Products consistent with its past practices and in the ordinary course of business from January 1, 2000 through the Effective Date.

(xi) All contracts relating to the Products, the Intellectual Property Rights and the Technology, as they relate exclusively to the Products, including all manufacturing, production, marketing and sales

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agreements related thereto, are assignable to Licensee.

(xii) All historical sales, costs of goods sold and operating expenses in connection with the Products are substantially accurate and properly classified on Licensor's financial statements and on any other written information provided by Licensor to Licensee in connection with this Agreement.

(b) Licensee hereby represents, warrants and covenants the following:

(i) Licensee is a corporation duly organized, existing and in good standing under the laws of the State of Iowa, U.S.A., with full right, power and authority to enter into and perform this Agreement.

(ii) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Licensee is a party, or Licensee's articles of organization or bylaws.

(iii) This Agreement has been duly executed and delivered by Licensee and is a legal, valid and binding obligation enforceable against Licensee in accordance with its terms.

(iv) Licensee shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(c) Indemnification.

(i) Licensor agrees to indemnify and hold harmless Licensee, its Affiliates and sublicensees and their respective employees, agents, officers and directors from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Licensee, its Affiliates or sublicensees arising out of or in connection with any (A) breach by Licensor of any representation, warranty, covenant or obligation hereunder, (B) act or omission on the part of

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Licensor or any of its employees or agents in the performance of this Agreement, (C) claim or demand of any kind or injury to a person or property arising from Licensor's or its contractor manufacturer's manufacturing, packaging or labeling of the Products; provided, that this indemnification shall not apply to the extent that such claim or demand has resulted from changes in such manufacturing, packaging or labeling conducted by or at the direction of Licensee after Closing, and (D) payments, commissions or fees of any kind due to consultants or brokers retained by Licensor relating to the Products.

(ii) Licensee agrees to indemnify and hold harmless Licensor and its Affiliates and their respective employees, agents, officers and directors from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Licensor or its Affiliates arising out of or in connection with any (A) breach by Licensee of any representation, warranty, covenant or obligation hereunder, (B) claim or demand of any kind for injury to person or property arising from Licensee's, its Affiliates' or sublicensee's manufacture, marketing, distribution and sale of the Products, provided, that this indemnification shall not apply to the extent such claim or demand has resulted from any negligent act or omission with respect to such Products by Licensor, its Affiliates, their employees, agents or contract manufacturers,
(C) act or omission on the part of Licensee or any of its employees or agents in the performance of this Agreement, (D) third party claims alleging infringement of such third parties' intellectual property rights as a result of the advertisement, promotion or marketing materials created by or at the direction of Licensee, its Affiliates or sublicensees and used in connection with the sale of the Products hereunder, and (E) payments, commissions or fees of any kind due to consultants or brokers retained by Licensee relating to the Products.

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(iii) A party seeking indemnification under this paragraph
11(c) (the "Indemnified Party") must give prompt written notice thereof to the other party (the "Indemnifying Party"). The Indemnifying Party shall have the right to defend any such claim or demand subject to the right of the Indemnified Party to participate with counsel of its choice in such defense, but the fees and expenses of such additional counsel shall be at the expense of the Indemnified Party. The Indemnified Party shall cooperate fully in all respects with the Indemnifying Party in any such compromise, settlement or defense, including, without limitation, by making available all pertinent information and personnel under its control to the Indemnifying Party. The Indemnifying Party will not compromise or settle any claim or demand (other than, after consultation with Indemnified Party, a claim or demand to be settled by the payment of money damages and/or the granting of releases) without the prior written consent of the Indemnified Party, which consent shall not be unreasonably withheld.

(iv) Each party shall maintain and keep in force for the term of this Agreement comprehensive general liability insurance including Products/Completed Operations, Contractual and Broad Form Property Damage covering its indemnification obligations hereunder with a minimum limit of Ten Million Dollars ($10,000,000) per annum combined single limit for Bodily Injury and Property Damage, to be increased as appropriate, consistent with prudent business practices prevailing in the business. Promptly after execution and delivery of this Agreement, each party shall furnish a certificate of insurance to the other party evidencing the foregoing endorsements, coverage and limits, and providing that such insurance shall not expire or be canceled or modified without at least thirty (30) days prior notice to the other party.

12. TERM OF LICENSE. Except as otherwise provided for herein, the term of the Agreement shall be for five (5) years from the Effective Date, and shall automatically renew for additional five (5) year periods unless either party provides the other with

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written notice of its intent not to renew this Agreement at least ninety (90) days prior to the expiration of the then current term.

13. TERMINATION.

(a) This Agreement may be terminated upon the mutual written agreement of the parties.

(b) Either party may terminate this Agreement forthwith by written notice to the other, if the other party commits a material breach of any part of this Agreement and such breach has not been remedied by the breaching party within sixty (60) days after written notice of such breach has been given by the other party. If the breach cannot be remedied within sixty
(60) days, the breaching party may submit a plan within this sixty (60) day period, reasonably acceptable to the other party, outlining the steps that it intends taking to cure the breach and then must cure the breach in accordance with the terms of such plan or be subject to an action by the other party for termination of this Agreement pursuant to this paragraph 13(b) for breach of such plan.

(c) This Agreement may also be terminated by written notice of one party, if the other party shall be involved in financial difficulties as evidenced:

(i) by its commencement of a voluntary case under any applicable bankruptcy code or statute, or by its authorizing, by appropriate proceedings, the commencement of such voluntary case; or

(ii) by its failing to receive dismissal of any involuntary case under any applicable bankruptcy code or statute within sixty (60) days after initiation of such action or petition; or

(iii) by its seeking relief as a debtor under any applicable law of jurisdiction finding it to be bankrupt or insolvent, or ordering or approving its liquidation, reorganization or any modification or alteration of the rights of its creditors or assuming custody of, or appointing a receiver or other custodian for, all or a substantial part of its property or assets; or

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(iv) by the entry of an order by a court of competent jurisdiction finding it to be bankrupt or insolvent, or during or approving its liquidation, reorganization or any modification or alteration of the rights of its creditors or assuming custody of, or appointing a receiver or other custodian for, all or a substantial part of its property or assets; or

(v) by its making an assignment for the benefit of, or entering into a composition with its creditors, or appointing or consenting to the appointment of a receiver or other custodian for all or a substantial part of its property.

(d) Licensee may terminate this Agreement at any time with ninety
(90) days written notice to Licensor if the Products are not a commercial success, as determined by Licensee in its sole discretion, or for reasons of safety or efficacy of the Products.

(e) Licensor may terminate this Agreement at any time with ninety
(90) days written notice to Licensee if Licensee fails to meet its marketing obligations set out in Section 6 above.

(f) The failure by a party to exercise its rights to terminate this Agreement pursuant to this Section 13 in the event of any occurrence giving rise thereto shall not constitute a waiver of such rights in the event of any subsequent occurrence.

(g) Termination of this Agreement shall not release either party from its obligations accrued prior to the effective date of termination nor deprive either party from any rights that this Agreement provides shall survive termination.

14. OPTION. Licensor hereby grants Licensee an option to purchase any or all of the applicable Intellectual Property Rights and Technology related exclusively to the Products at any time during the term hereof upon ninety (90) days written notice to Licensor. The purchase price for such Intellectual Property Rights and Technology shall be an amount equal to one times the average annual Net Sales of such Products from 1999 until the date Licensor exercises the option; provided, however, such purchase price shall not be less than the average annual Net Sales of such Products in 1999. The

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purchase of such Intellectual Property Rights and Technology shall include, at no additional cost or expense, any necessary license of the Technology or Patents or Intellectual Property Rights from third parties. The closing, which closing shall be established by Licensor and Licensee, shall be no later than one hundred twenty (120) days after Licensor receives Licensee's written notice of its election to exercise the option to purchase such Intellectual Property Rights and Technology.

In addition, Licensor hereby grants Licensee a right of first refusal to purchase or license the Products in other territories as such purchases or licenses may become available.

15. PUBLICITY. The parties hereto shall coordinate the preparation and issuance of any public announcement of Agreement. Any such announcement shall comply with relevant Securities and Exchange Commission requirements and shall take into account any reasonable concern regarding the trade. The wording of such announcement shall be agreed upon by the parties before release.

16. AUDITS. Licensee shall keep accurate records of all Product sales and other relevant data concerning the Products for a period of two (2) years following the year in which such records were created, and Licensee shall provide Licensor quarterly reports thereof thirty (30) days after the end of the applicable calendar quarter. Such reports shall state the number of Units of Product sold by Licensee, its Affiliates or sublicensees, if any, during the applicable quarter, as well as the number of free samples of the Products distributed, any Product returns made during such calendar quarter, together with an accounting of Net Sales with respect to such calendar quarter. Once a year, upon reasonable notice, at times mutually agreed upon and during business hours, Licensor, at Licensor's cost, may have the accounts of Licensee, its Affiliates or sublicensees for the preceding two (2) calendar years relating to the Products reviewed by independent certified public accountants appointed by Licensor and reasonably approved by Licensee, solely in order to verify amounts due under this Agreement. Licensor and Licensee shall mutually determine a general strategy for such audit in advance of its conduct. Said accountant shall not disclose to Licensor any information except that which should properly be contained in a quarterly report required under this Agreement. Licensee shall promptly pay any underpayment evidenced by such audit, and Licensor shall promptly refund any overpayment evidenced by such audit. If such an audit evidences an underpayment of more than five percent (5%) with respect to the amounts actually paid, Licensee shall promptly pay such underpayment to Licensor with interest at the prime rate as set by Citibank, from the time when such underpayment accrued, and shall reimburse Licensor for the reasonable costs and expenses (including fees) of such audit.

17. ARBITRATION.

(a) ARBITRATION. In the event of any dispute (a "Dispute") between the parties hereto subsequent to the Effective Date with respect to the breach, interpretation or

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enforcement of this Agreement, such dispute shall be resolved by binding arbitration in accordance with the commercial arbitration rules of the American Arbitration Association ("AAA"). Notwithstanding the foregoing, the parties intend to depart from the AAA commercial arbitration rules to the extent any of the following provisions conflict with such rules.

(b) PANEL. Any arbitration shall take place before a panel of three (3) arbitrators (the "Panel"). The Panel shall be selected in accordance with the AAA's procedures for selecting an arbitration Panel, provided, that the Panel shall include one certified public accountant and one transactional lawyer, each of whom shall have had at least ten (10) years experience in his or her respective field, and at least three (3) years of arbitration experience. If any arbitrator on the Panel neglects or refuses to act or is or becomes incapable of acting, or dies before the Panel shall have made its award, and the parties fail to agree or concur in the appointment of another arbitrator, either party may serve on the other a notice in writing requiring him to agree and concur in the appointment of another arbitrator, and if such appointment is not made within twenty (20) days from the service of said notice, then the remaining arbitrators shall have power on the request in writing of either party to appoint another arbitrator who shall have the like authority to act in the arbitration and make an award and the like powers in all respects as if he had been appointed by the parties.

(c) BINDING EFFECT. Each of the parties agrees that the decision of the Panel shall be final and binding on the parties hereto and, provided diversity or other federal jurisdiction exists, the parties hereby consent to the entry of final judgment thereon in the United States District Court for the Southern District of New York, and to the issuance of execution on the judgment. The award may be appealed only to the court in which judgment on the award is required to be entered and only to the extent the award contains material errors of applicable law, is arbitrary or capricious, or was fraudulently obtained. If the parties cannot meet the applicable requirements for federal jurisdiction, the parties agree to the entry of judgment in the State Court of New York, and to the issuance of execution on such judgment. The parties hereto hereby

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consent to the jurisdiction of such court (i.e., such federal court, or, in the event federal jurisdiction does not exist, such state court) in reference to any matter arising out of the arbitration or this Agreement including but not limited to confirmation of any arbitration award and enforcement thereof by entry of judgment thereon or by any other legal remedy. As to any Dispute which under the terms hereof is made subject to arbitration, no suit at law or in equity based on such Dispute shall be instituted by either party hereto other than to enforce the award of the Panel. If any controversy shall arise after the award as to whether the award or any part thereof has been complied with, such controversy shall be determined by the same Panel.

(d) EVIDENCE. The Panel shall not be bound by strict rules of evidence and may give such right to evidence as may seem right and proper to it. The Panel shall schedule a pre-hearing conference to resolve procedural matters, arrange for the exchange of information, obtain stipulations, and narrow the issues. The parties will submit proposed discovery schedules to the Panel at the pre- hearing conference. The scope and duration of discovery will be within the sole discretion of the Panel. Unresolved discovery disputes may be brought to the attention of the chair of the arbitration panel and may be disposed of by the chair of the panel. The Panel shall have the discretion to order a pre-hearing exchange of information by the parties, including, without limitation, production of requested documents, exchange of summaries of testimony of proposed witnesses, and examination by deposition of parties and third-party witnesses. This discretion shall be exercised in favor of discovery reasonable under the circumstances. The arbitration shall be conducted in New York, New York. Any party may be represented by counsel or other authorized representative. In rendering a decision(s), the Panel shall determine the rights and obligations of the parties according to the substantive and procedural laws of New York and the terms and provisions of this Agreement. The Panel's decision shall be based on the evidence introduced at the hearing, including all logical and reasonable inferences therefrom. The Arbitrator may make any determination, and/or grant any remedy or relief that is just and equitable, subject to the express provisions of this Agreement. The Panel shall have power to award and direct that the parties

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or any of them shall execute such releases, conveyances, assurances, and do things as the Panel shall think fit and such releases, conveyances, assurances and things shall be executed and done accordingly. The Panel shall have the authority to proceed ex parte in case of the nonattendance of either of the parties or of their witnesses after thirty (30) days prior notice in writing by the Panel given to the parties respectively or their respective attorneys or agents notifying the time and place of meeting to proceed with the reference. Any provisional remedy that would be available from a court of law shall be available from the arbitrator to the parties to this Agreement pending arbitration.

(e) WAIVER OF CONSEQUENTIAL DAMAGES. The Panel shall have no authority to award consequential damages, punitive damages, and all other damages not measured by the prevailing party's actual damages, and each party hereby waives all claims to same. The Panel may not in any event make any ruling, finding or award that does not conform to the terms and conditions of the Agreement. Liabilities for taxes are direct damages.

(f) DISCLOSURE. Except to the extent disclosure, filing, reporting or announcement thereof is required by law, including by any rules or regulations of any applicable governmental, regulatory or stock exchange agency or authority, neither a party nor an arbitrator may disclose the existence, content or results of any arbitration hereunder without the prior written consent of both parties, except to the extent that the recordation of a final judgment causes such matters to become public.

18. RIGHT OF FIRST OFFER AND REFUSAL. If at any time during the term of this Agreement, Licensor desires to market, sell or distribute in the Territory any over-the- counter product closely related to the Field, then Licensor shall provide Licensee the right of first offer and refusal to present a proposal to Licensor to market and distribute any such product on an exclusive basis within the Territory.

19. NOTICES. All notices required hereunder shall be in writing and shall be deemed to be properly given if sent by air courier to the party to be notified at the address set forth on page 1 hereof, or at such other latest address as either party may hereafter designate in writing to the other; provided that a copy of each notice to be sent to Licensor hereunder shall also be sent by the same means to William J. Bologna, Chairman of the Board, Columbia Laboratories, Inc., 2875 N.E. 191 St., Suite 400,

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Aventura, Florida 33180; and further provided that a copy of each notice set to Licensee hereunder shall also be sent by the same means to Chris DeWolf, 1201 Continental Place NE, Cedar Rapids, Iowa 52402. The date of service of any notice to sent by air courier shall be the date of receipt.

20. TAX. All taxes levied on account of any payments accruing under this Agreement that constitute income to Licensor, shall be the obligation of Licensor, and if provision is made in law or regulation for withholding, such tax shall be deducted from any payment then due, paid to the proper taxing authority, and receipt for payment of the tax secured and promptly sent to Licensor.

21. INDEPENDENT CONTRACTORS. The relationship of the parties under this Agreement is that of independent contractors. Neither party shall be deemed to be the agent of the other and neither is authorized to take any action binding upon the other.

22. ENTIRE AGREEMENT; MODIFICATION. This Agreement, including the Schedules hereto, contains the entire understanding between the parties hereto relating to the subject matter hereof, there being no terms and conditions other than those set forth herein, and it supersedes all prior agreements, written or oral, between the parties hereto with respect to the matters covered hereunder. This Agreement may not be modified, altered or otherwise changed other than by an instrument in writing, duly executed by each of the parties hereto.

23. SEVERABILITY. If any provision of this Agreement should be or becomes fully or partly invalid or unenforceable for any reason whatsoever or should be adjudged to violate any applicable law, this Agreement is to be considered divisible as to such provision and such provision is deemed to be deleted from this Agreement, and the remainder of this Agreement shall be valid and binding as if such provision were not included herein; provided, however, that this Agreement is not rendered fundamentally different in its content or effect.

24. EFFECT OF HEADINGS. The headings for the sections and paragraphs of this Agreement are to facilitate reference only, do not form a part of this Agreement, and shall not in any way affect the interpretation hereof.

25. CHOICE OF LAW. This Agreement and performance hereof shall be construed and governed by the laws of the State of New York and of the United States. Any dispute, controversy, claim or difference arising between the parties out of, relating to, or in connection with this Agreement shall be submitted to the jurisdiction of the courts sitting in the State of Iowa or the State of New York, at the option of the party filing such action.

26. NO WAIVER. No delay or omission or failure to exercise any right or remedy provided for herein shall be deemed to be a waiver thereof or acquiescence in the event giving rise to such right or remedy.

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27. COUNTERPARTS. This Agreement may be executed in any number of counterparts and by the different parties hereto on separate counterparts, each of which, when so executed shall be deemed an original, but all such counterparts shall constitute but one and the same instrument.

28. FURTHER ASSURANCES. Licensor and Licensee each agree to produce or execute such other documents or agreements as may be necessary or desirable for the execution and implementation of this Agreement and the consummation of the transactions contemplated hereby.

29. BANKRUPTCY. All Trademark, Patent and Technology rights and licenses granted to the Products under or pursuant to this Agreement by Licensor to Licensee are, and shall otherwise be deemed to be, for purposes of
Section 365(n) of the United States Bankruptcy Code, as amended from time to time (the "Bankruptcy Code"), licenses of rights to "intellectual property" as defined under Section 101 (35A) of the Bankruptcy Code. The parties hereto agree that so long as Licensee, as a licensee of such rights under this Agreement, makes all payments to Licensor required under this Agreement, Licensee shall retain and may fully exercise all of its rights and elections under the Bankruptcy Code. The parties further agree that, if any proceeding shall be instituted by or against Licensor seeking to adjudicate it as bankrupt or insolvent, or seeking liquidation, winding up, reorganization, arrangement, adjustment, protection, relief or composition of it or its debts under any law relating to bankruptcy, insolvency or reorganization or relief of debtors, or seeking an entry of an order for relief or the appointment of a receiver, trustee or other similar official for its or any substantial part of its property or appointment of a receiver, trustee or other similar official for it or any substantial part of its property or it shall take an action to authorize any of the foregoing actions, Licensee, as a licensee of such rights under this Agreement, shall retain and may fully exercise all of its rights and elections under the Bankruptcy Code. The parties further agree that, in the event of the commencement of a bankruptcy proceeding by or against Licensor under the Bankruptcy Code, Licensee shall be entitled to a complete duplicate of (or complete access to, as appropriate) any such intellectual property and all embodiment of such intellectual property, and the same, if not already in its possession, shall be promptly delivered to Licensee (i) upon any such commencement of a bankruptcy proceeding upon written requires therefor by Licensee, unless Licensor elects to continue to perform all of its obligations under this Agreement, or (ii) if not delivered under (i) above, upon the rejection of this Agreement by or on behalf of Licensor, upon written request therefor by Licensee. In addition the parties agree that in such event the intellectual property delivered to Licensee shall include all Technology necessary or useful to give Licensee the capability of manufacturing the Products and such Technology shall be delivered to Licensee in such a way as to communicate it to Licensee promptly, effectively and economically.

30. FORCE MAJEURE. No failure or omission by a party hereto in the performance of any obligation of this Agreement shall be deemed a breach of this Agreement nor shall

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it create any liability if the same shall arise from any cause or causes beyond the control of the party, including, but not limited to, the following, which, for the purposes of this Agreement, shall be regarded as beyond the control of the party in question: acts of God, acts or omissions of any government, any rules, regulations, or orders issued by any governmental authority or any officer, department, agency, or instrumentality thereof, fire, storm, flood, earthquake, accident, war, rebellion, insurrection, riot, invasion, strikes, lockouts; provided however, that the party so affected shall promptly advise the other party of the existence of such causes of nonperformance, shall use its best efforts to avoid or remove such causes of nonperformance and shall continue hereunder wit the utmost dispatch whenever such causes are removed.

31. PERFORMANCE BY AFFILIATES. The parties agree that certain of their rights and obligations under this Agreement may not be carried out by one or more of their Affiliates; provided, however, that each party shall remain responsible for the acts and omission of its Affiliates. The parties further understand and agree that no such Affiliate is a party to this Agreement, and, except as contemplated by this Agreement, is not the agent of such party for purposes hereof, is not authorized to bind such party and cannot enter into amendments to this Agreement, which can only be made in accordance with the terms of Section 22 hereof.

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IN WITNESS WHEREOF, the parties hereto have set their hands as of the day and year first above written.

COLUMBIA LABORATORIES, INC.                   LIL' DRUG STORE PRODUCTS, INC.

By:/S/ WILLIAM J. BOLOGNA                     By:/S/ DENNIS L. OLDORF
   ----------------------                        --------------------
   William J. Bologna, Chairman of               Dennis L. Oldorf, Chairman of
                         the Board                                   the Board

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EXHIBIT 10.24

DISTRIBUTION AGREEMENT

This Distribution Agreement (the "Agreement") is made and entered into as of this 18th day of April, 2000 by and between Columbia Laboratories, Inc., a Delaware corporation having its principal place of business at 2875 N.E. 191st St., Suite 400, Aventura, Florida ("Columbia"), and Lil' Drug Store Products, Inc., an Iowa corporation with its principal place of business at 1201 Continental Place NE, Cedar Rapids, Iowa ("Lil' Drug Store Products");

WITNESSETH:

WHEREAS, Columbia has the right to sell certain Product (as hereinafter defined); and

WHEREAS, Columbia wishes to obtain the services of Lil' Drug Store Products to establish distribution channels for sale of the Product in the Territory (as hereinafter defined), and Lil' Drug Store Products wishes to engage in distribution of the Product in the Territory, on the terms and subject to the conditions set forth herein;

NOW, THEREFORE, for and in consideration of the mutual promises and covenants herein contained, the parties hereto agree as follows.

1. DEFINITIONS. As used in this Agreement, the following terms (except as otherwise expressly provided or unless the context otherwise requires) shall have the respective meanings set forth below (it being understood that the terms defined in this Agreement shall include the singular number in the plural, and the plural number in the singular):

(a) "Affiliate" shall mean any corporation or other business entity that either directly or indirectly controls a party to this Agreement, is controlled by such party, or is under common control of such party. As used herein, the term "control" means possession of the power to direct or cause the direction of the management and policies of a corporation or other entity, whether through the ownership of voting securities, by contract or otherwise.

(b) "Confidential Information" shall mean all information and/or technical data that is disclosed by one party hereto to the other party hereto pursuant to this Agreement, whether written or oral, that the disclosing party treats as confidential and identifies as such (by marking written information "Confidential" and if oral, by promptly reducing it to writing and marking it "Confidential"), other than (i) information known to the receiving party or its Affiliates prior to the disclosure of such information to such party, provided said prior knowledge is supportable by documentary evidence, (ii) information which at the time of the disclosure is generally known to the public, provided that such public knowledge does not result from any act or disclosure by the receiving party or one of its Affiliates in violation of the terms of this Agreement or of any other confidentiality obligation owed to the disclosing party, (iii) information that can be shown to be independently discovered, after the date hereof, by a party, or one of its Affiliates, without the aid, application or use of the disclosed information, or (iv) information obtained by the receiving party from a third party that is determined to be in lawful possession of such information, provided such third party is not in violation of any contractual or legal obligation to the disclosing party or one of its Affiliates with respect to such information.

(c) "Effective Date" shall mean the date May 5, 2000.


(d) "Net Sales" shall mean the aggregate equivalent of gross sales received by Lil' Drug Store Products or its Affiliates from or on account of the sale of the Product to non-affiliated third parties on which payments are due under this Agreement, less (i) credits or allowances, if any, actually granted on account of cash or trade discounts, recalls, rebates, rejection or return of the Product previously sold, and (ii) excises, sales taxes, value added taxes, consumptions taxes, duties or other taxes imposed upon and paid with respect to such sales (excluding income or franchise taxes of any kind). Net Sales shall not include any transfer between Lil' Drug Store Products and any of its Affiliates for resale. No transfer of the Product for test or development purposes or as free samples shall be considered a sale hereunder for accounting and payment purposes. Net Sales shall be determined in accordance with generally accepted accounting principles ("GAAP").

(e) "Product" shall mean the current formulation of DIASORB(R) brand aluminum magnesium silicate products for use as a drug for human health purposes, and any and all improvements, reformulations, or advances to such formulation.

(f) "Territory" shall mean the United States of America and its territories.

(g) "Trademark" shall mean the United States trademark DIASORB (Reg. No. 1,211,235), and any variations thereof.

(h) "Unit" shall mean a single item package of the Product.

2. RIGHTS GRANTED

(a) Columbia grants to Lil' Drug Store Products, and Lil' Drug Store Products accepts from Columbia, on the terms and conditions stated herein, an exclusive (even as to Columbia and Columbia's Affiliates) right to use the Trademark only in connection with marketing and sale of the Product in the Territory, and a nonexclusive right (but exclusive as to Columbia and Columbia's Affiliates) to market, distribute, and sell the Product, only in connection with the Trademark and only in the Territory.

(b) Columbia shall not use, nor permit any party to use, the Trademark or any similar mark on any other product marketed, used or sold in the Territory without the prior written consent of Lil' Drug Store Products. Lil' Drug Store Products shall not (1) use nor permit any party to use, the Trademark with any other product marketed, used, or sold in the Territory, (2) sell the Product or permit the Product to be sold outside the Territory, or (3) use the Trademark in any manner outside the Territory.

(c) To the extent reasonable and necessary for Lil' Drug Store Products to fulfill its obligations hereunder, Columbia shall transfer or grant Lil' Drug Store Products the rights to use Columbia's art work, customer lists, records, web-sites, contracts, advertising/media schedules in connection with the manufacturing, production, use or sale of the Product in the Territory.

(d) From and after the Effective Date, Columbia will reasonably make available to Lil' Drug Store Products all staff necessary to support the transition of the Product and the distribution of same, with such staff to include, but not be limited to, the Director of Sales, the Vice President of Research and Development, the Corporate Controller, and the Chairman and CEO. The parties anticipate the transition period will last at least ninety (90) days, and both parties agree to use their respective best efforts in the transition.

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(e) Columbia will coordinate all supply of the Product, and will use its best efforts to insure Lil' Drug Store Products does not face capacity restrictions for its supply of the Product. Columbia will designate an individual with Columbia to work with Lil' Drug Store Products on all supply matters. Lil' Drug Store Products shall reimburse Columbia for its costs of the Product (bill of materials multiplied by the amount of the Product, plus necessary freight/transportation charges) in U.S. dollars promptly upon receipt and reasonable inspection of the Product. Seller will promptly notify Buyer of any increase in the cost of the Product or the freight/transportation charges. Columbia and Lil' Drug Store Products agree to work together to secure all necessary contracts to protect the supply of the Product and will work together to explore and qualify more cost effective methods of manufacture for producing the Product.

3. PRODUCT FEES, RIGHTS, AND PAYMENTS.

(a) In consideration of the services to be provided by Lil' Drug Store Products hereunder, Lil' Drug Store Products shall pay to Columbia (aside from the cost of the Product) twenty percent (20%) of the Net Sales of the Product during the term hereof, retaining all other moneys from the Net Sales. Such payments are to be paid to Columbia within (thirty) 30 days after the end of the second month following the Effective Date, and thereafter on a monthly basis within thirty (30) days after the close of each month. Each payment shall be accompanied by documentation evidencing the Net Sales for the previous period.

(b) During the term of the Agreement, Columbia shall not sell, or license for sale, to any other distributor or licensee the Product for sale or marketing in the Territory. Columbia represents that as of the Effective Date it has not entered into any arrangement that would contravene the intentions of this paragraph.

(c) All Product manufactured and supplied hereunder shall meet the quality control specifications and the specifications in the applicable regulatory filing through the expiration date stated on that Product package. Such Product shall also not be adulterated or misbranded within the meaning of the U.S. Food, Drug and Cosmetic Act, as amended.

(d) Lil' Drug Store Products shall from time to time notify Columbia of the quantity of Product it wishes to order. Lil' Drug Store Products shall pay Columbia for the Product purchased within the first two months after the Effective Date within thirty (30) days after the end of such second month following the Effective Date and thereafter on a monthly basis within thirty
(30) days after the close of each month in which Lil' Drug Store Products purchases Product.

4. RETURNS AND COMMITMENTS.

Columbia shall be responsible for any returns of Product sold and shipped by Columbia prior to the Effective Date ("Returns"). Lil' Drug Store Products shall be entitled to a credit against the next payment due to Columbia hereunder for Returns as follows: (i) a credit equal to the gross margin (net wholesale price less cost of goods sold) on such Returns; or (ii) a credit equal to the amount of any refund paid by Lil' Drug Store Products for any Returns of expired or damaged Product. Expired Product shall mean Units of Product that have eighteen (18) months or less before their expiration date. Damaged Product shall include, but are not limited to, those Product with a retailer's inventory or pricing marking affixed, if they are not resellable. Notwithstanding the above, if Lil' Drug Store Products sells any returned Product after receiving a credit for such returned Product, Lil' Drug Store Products shall pay Columbia the Net Sales of


such returned Product, less any out of pocket expenses incurred by Lil' Drug Store Products in such sale.

To the extent Lil' Drug Store Products, in its reasonable judgment, is required to honor any documented customer commitment, Columbia will promptly reimburse Lil' Drug Store Products for such commitment. Lil' Drug Store Products shall provide Columbia with all necessary financial records to verify such commitment. A documented customer commitment shall mean any written documentation related to financial or non-financial customer or broker commitments made by Columbia related to the Product. Commitments may include customer or broker rebates, deductions, credits, allowances, promotional guarantees, bill backs and SPIFFS. Such documented customer commitments must clearly indicate that Columbia and/or its representatives agreed to such commitment. If a customer or broker commitment is undocumented, Lil' Drug Store Products and Columbia agree to review such alleged commitment and, subject to Columbia's approval, which approval shall not be unreasonably withheld, Columbia will promptly reimburse Lil' Drug Store Products for any commitment Lil' Drug Store Products makes to honor such undocumented customer or broker commitment.

5. MARKETING.

(a) Lil' Drug Store Products will use reasonable efforts to market and sell the Product in the Territory, which may include use of samples, national media marketing plans, coop advertising, trade shows, etc., and Columbia may, at its option, participate in or support such marketing efforts.

(b) Lil' Drug Store Products will timely provide quarterly sales and other marketing information useful to Columbia in monitoring sales progress.

(c) Lil' Drug Store Products and Columbia shall each promptly disclose to the other party to this Agreement any regulatory action or inquiry concerning the Product. Columbia shall promptly notify Lil' Drug Store Products of all communications and responses regarding such regulatory action or inquiry.

(d) Lil' Drug Store Products will maintain a qualified national sales force to sell/promote the Product.

6. THE TRADEMARK.

(a) Maintenance

Columbia promptly shall keep Lil' Drug Store Products currently advised of the status of the Trademark. Columbia shall bear all costs for the maintenance of the Trademark.

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(b) Trademark Use and Quality Control

(i) Lil' Drug Store Products agrees to use the Trademark in accordance with good customary trademark practice, and to avoid taking any action that would in any manner impair or detract from the value of the Trademark, or the goodwill and reputation of Columbia; provided, however, Lil' Drug Store Products may modify and/or redesign the labels and other packaging of the Product with Columbia's prior written approval, which approval shall not be unreasonably withheld. Lil' Drug Store Products acknowledges Columbia's ownership of rights to the Trademark and of all related goodwill.

(ii) Lil' Drug Store Products agrees to use the Trademark only in the form and manner and with appropriate legends as approved from time to time by Columbia, and not to use or allow use of any other trademark or service mark in combination with the Trademark without the prior written approval of Columbia, provided that such approval shall not be unreasonably withheld.

7. INFRINGEMENT OF TRADEMARK.

Lil' Drug Store Products and Columbia shall each promptly notify the other following the discovery of any alleged infringement or unauthorized use of the Trademark that may come to their attention. Columbia shall promptly undertake, at Columbia's expense, commercially reasonable efforts to obtain a discontinuance of the infringement or unauthorized use and, if not successful, Columbia may, at its sole option, bring suit against such infringement.

8. INFRINGEMENT OF THIRD-PARTY INTELLECTUAL PROPERTY RIGHTS.

(a) Each party hereto shall notify the other promptly of the receipt of notice of any action, suit or claim alleging infringement of any third party's intellectual property rights on the grounds of any activities by either party hereto involving the Product or the Trademark.

(b) In no event shall either party settle any such allegation of infringement without the prior written consent of the other, which consent shall not be unreasonably withheld or delayed.

9. CONFIDENTIALITY. Each party hereto shall hold all Confidential Information in confidence, use it only in connection with the performance of its obligations pursuant to this Agreement and use its diligent effects (consistent with those it uses to safeguard its own confidential information) to safeguard Confidential Information and to prevent the unauthorized use or disclosure of any Confidential Information. Each party hereto shall ensure that its Affiliates or employees who have access to any Confidential Information shall be made aware of and subject to these obligations. The receiving party may disclose Confidential Information to regulatory authorities for the purpose of seeking marketing approval of the Product pursuant to this Agreement and may also disclose Confidential Information to individuals who have a need to know to effectuate the development and commercialization of the Product pursuant to this Agreement, provided such individual is bound by a confidentiality obligation comparable to the obligation set forth in this Section 9. The obligations of the parties hereto under this Section 9 shall survive the expiration or termination of this Agreement.

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10. REPRESENTATIONS, WARRANTIES AND COVENANTS AND INDEMNIFICATION.

(a) Columbia hereby represents, warrants and covenants the following:

(i) Columbia is a corporation duly organized, existing and in good standing under the laws of Delaware, with full right, power and authority to enter into and perform this Agreement and to grant all of the rights, powers and authorities herein granted.

(ii) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Columbia is a party, or Columbia's articles of incorporation or bylaws.

(iii) This Agreement has been duly executed and delivered by Columbia and is a legal, valid and binding obligation enforceable against Columbia in accordance with its terms.

(iv) Columbia shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(v) As of the Effective Date, Columbia knows of no issued or pending patents, trademarks or patent or trademark applications relating to the Product that would prevent Lil' Drug Store Products from marketing or selling the Product in the Territory.

(vi) As of the Effective Date, there are no outstanding, pending or threatened product liability or breach of warranty or other similar claims, actions, suits, demands, investigations, arbitrations, administrative or other proceedings, or orders, injunctions, judgments or decrees of any court or government agency in connection with the Product in the Territory.

(vii) As of the Effective Date, there are no outstanding, pending or threatened violations, notice of noncompliance, warning letters, orders, injunctions, judgments or decrees of any court or government agency, investigations, claims, actions, suits, demands, administrative or other proceedings that have resulted or might result in the revocation, suspension or modification of any regulatory approval for the Product in the Territory.

(viii) Columbia has conducted the sales of the Product consistent with its past practices and in the ordinary course of business.

(ix) Columbia ceased, as of March 13, 2000, all further sales of the Product to Quality King.

(x) All historical sales, costs of goods sold and operating expenses are substantially accurate and properly classified on Columbia's financial statements and on any other written information provided to Lil' Drug Store Products by Columbia in connection with this transaction.

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(b) Lil' Drug Store Products hereby represents, warrants and covenants the following:

(i) Lil' Drug Store Products is a corporation duly organized, existing and in good standing under the laws of the State of Iowa, with full right, power and authority to enter into and perform this Agreement.

(ii) The execution, delivery and performance of this Agreement do not conflict with, violate or breach any agreement to which Lil' Drug Store Products is a party, or Lil' Drug Store Products' articles of organization or bylaws.

(iii) This Agreement has been duly executed and delivered by Lil' Drug Store Products and is a legal, valid and binding obligation enforceable against Lil' Drug Store Products in accordance with its terms.

(iv) Lil' Drug Store Products shall comply with all applicable laws, consent decrees and regulations of any federal, state or other governmental authority in performing this Agreement.

(c) Indemnification.

(i) Columbia agrees to indemnify and hold harmless Lil' Drug Store Products, its Affiliates and ad their respective employees, agents, officers and directors from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Lil' Drug Store Products or its Affiliates arising out of or in connection with any (A) breach by Columbia of any representation, warranty, covenant or obligation hereunder, (B) act or omission on the part of Columbia or any of its employees or agents in the performance of this Agreement, (C) payments, commissions or fees of any kind due to consultants or brokers retained by Columbia relating to the Product, and (D) claim or demand of any kind for injury to a person or property arising from Columbia's or its contract manufacturer's manufacturing, packaging or labeling of the Product; provided, that this indemnification shall not apply to the extent such claim or demand has resulted from changes in such manufacturing, packaging or labeling conducted at the direction of Lil' Drug Store Products after the Effective Date.

(ii) Lil' Drug Store Products agrees to indemnify and hold harmless Columbia and its Affiliates and their respective employees, agents, officers and directors from and against any claims, losses, liabilities, damages, costs and expenses (including reasonable attorney fees) incurred by Columbia or its Affiliates arising out of or in connection with any (A) breach by Lil' Drug Store Products of any representation, warranty, covenant or obligation hereunder, (B) claim or demand of any kind for injury to person or property arising from Lil' Drug Store Products' or its Affiliates' marketing, distribution and sale of the Product, provided, that this indemnification shall not apply to the extent such claim or demand has resulted from any negligent act or omission with respect to such Product by Columbia, its Affiliates, their employees, agents or contract manufacturers, (C) act or omission on the part of Lil' Drug Store Products or any of its employees or agents in the performance of this Agreement, (D) third party claims alleging infringement of such third parties' intellectual property rights as a result of the advertisement, promotion or marketing materials created by or at the direction of Lil' Drug Store Products, or its Affiliates and used in connection with the sale of the Product hereunder, and (E)

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payments, commissions or fees of any kind due to consultants or brokers retained by Lil' Drug Store Products relating to the Product.

(iii) A party seeking indemnification under this paragraph
10(c) (the "Indemnified Party") must give prompt written notice thereof to the other party (the "Indemnifying Party"). The Indemnifying Party shall have the right to defend any such claim or demand subject to the right of the Indemnified Party to participate with counsel of its choice in such defense, but the fees and expenses of such additional counsel shall be at the expense of the Indemnified Party. The Indemnified Party shall cooperate fully in all respects with the Indemnifying Party in any such compromise, settlement or defense, including, without limitation, by making available all pertinent information and personnel under its control to the Indemnifying Party. The Indemnifying Party will not compromise or settle any claim or demand (other than, after consultation with Indemnified Party, a claim or demand to be settled by the payment of money damages and/or the granting of releases) without the prior written consent of the Indemnified Party, which consent shall not be unreasonably withheld.

(iv) Each party shall maintain and keep in force for the term of this Agreement comprehensive general liability insurance including Product/Completed Operations, Contractual and Broad Form Property Damage covering its indemnification obligations hereunder with a minimum limit of Ten Million Dollars ($10,000,000) per annum combined single limit for Bodily Injury and Property Damage, to be increased as appropriate, consistent with prudent business practices prevailing in the business. Promptly after execution and delivery of this Agreement, each party shall furnish a certificate of insurance to the other party evidencing the foregoing endorsements, coverage and limits, and providing that such insurance shall not expire or be canceled or modified without at least thirty (30) days prior notice to the other party.

11. TERM. Except as otherwise provided for herein, the term of the Agreement shall be for five (5) years from the Effective Date, and shall automatically renew for additional five (5) year periods unless either party provides the other with written notice of its intent not to renew this Agreement at least ninety (90) days prior to the expiration of the then current term.

12. TERMINATION.

(a) This Agreement may be terminated upon the mutual written agreement of the parties.

(b) Either party may terminate this Agreement forthwith by written notice to the other, if the other party commits a material breach of any part of this Agreement and such breach has not been remedied by the breaching party within sixty (60) days after written notice of such breach has been given by the other party. If the breach cannot be remedied within sixty (60) days, the breaching party may submit a plan within this sixty (60) day period, reasonably acceptable to the other party, outlining the steps that it intends taking to cure the breach and then must cure the breach in accordance with the terms of such plan or be subject to an action by the other party for termination of this Agreement pursuant to this paragraph 12(b) for breach of such plan.

(c) This Agreement may also be terminated by written notice of one party, if the other party shall be involved in financial difficulties as evidenced:

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(i) by its commencement of a voluntary case under any applicable bankruptcy code or statute, or by its authorizing, by appropriate proceedings, the commencement of such voluntary case; or

(ii) by its failing to receive dismissal of any involuntary case under any applicable bankruptcy code or statute within sixty (60) days after initiation of such action or petition; or

(iii) by its seeking relief as a debtor under any applicable law of jurisdiction finding it to be bankrupt or insolvent, or ordering or approving its liquidation, reorganization or any modification or alteration of the rights of its creditors or assuming custody of, or appointing a receiver or other custodian for, all or a substantial part of its property or assets; or

(iv) by the entry of an order by a court of competent jurisdiction finding it to be bankrupt or insolvent, or during or approving its liquidation, reorganization or any modification or alteration of the rights of its creditors or assuming custody of, or appointing a receiver or other custodian for, all or a substantial part of its property or assets; or

(v) by its making an assignment for the benefit of, or entering into a composition with its creditors, or appointing or consenting to the appointment of a receiver or other custodian for all or a substantial part of its property.

(d) Lil' Drug Store Products may terminate this Agreement at any time with ninety (90) days written notice to Columbia if the Product are not a commercial success, as determined by Lil' Drug Store Products in its sole discretion, or for reasons of safety or efficacy of the Product.

(e) Columbia may terminate this Agreement at any time with ninety (90) days written notice to Lil' Drug Store Products if the marketing standards set forth in this Agreement are not being met by Lil' Drug Store Products.

(f) The failure by a party to exercise its rights to terminate this Agreement pursuant to this Section 12 in the event of any occurrence giving rise thereto shall not constitute a waiver of such rights in the event of any subsequent occurrence.

(g) Termination of this Agreement shall not release either party from its obligations accrued prior to the effective date of termination nor deprive either party from any rights that this Agreement provides shall survive termination.

13. PUBLICITY. The parties hereto shall coordinate the preparation and issuance of any public announcement of this Agreement. Any such announcement shall comply with relevant Securities and Exchange Commission requirements and shall take into account any reasonable concern regarding the trade. The wording of such announcement shall be agreed upon by the parties before release.

14. AUDITS. Lil' Drug Store Products shall keep accurate records of all Product sales and other relevant data concerning the Product for a period of two (2) years following the year in which such records were created, and Lil' Drug Store Products shall provide Columbia quarterly reports thereof thirty (30) days after the end of the applicable calendar quarter. Such reports shall state the number of Units of Product sold by Lil' Drug Store Products and its Affiliates

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during the applicable quarter, as well as the number of free samples of the Product distributed, any Product returns made during such calendar quarter, together with an accounting of Net Sales with respect to such calendar quarter. Once a year, upon reasonable notice, at times mutually agreed upon and during business hours, Columbia, at Columbia's cost, may have the accounts of Lil' Drug Store Products or its Affiliates for the preceding two (2) calendar years relating to the Product reviewed by independent certified public accountants appointed by Columbia and reasonably approved by Lil' Drug Store Products, solely in order to verify amounts due under this Agreement. Columbia and Lil' Drug Store Products shall mutually determine a general strategy for such audit in advance of its conduct. Said accountant shall not disclose to Columbia any information except that which should properly be contained in a quarterly report required under this Agreement. Lil' Drug Store Products shall promptly pay any underpayment evidenced by such audit, and Columbia shall promptly refund any overpayment evidenced by such audit. If such an audit evidences an underpayment of more than five percent (5%) with respect to the amounts actually paid, Lil' Drug Store Products shall promptly pay such underpayment to Columbia with interest at the prime rate as set by Citibank, from the time when such underpayment accrued, and shall reimburse Columbia for the reasonable costs and expenses (including fees) of such audit.

15. OPTION. Columbia hereby grants Lil' Drug Store Products an option as follows: at any time during the term hereof upon ninety (90) days written notice to Columbia, Lil' Drug Store Products may purchase from Columbia Columbia's best efforts to facilitate procurement for Lil' Drug Store Products, directly from Columbia's Licensor, of (a) a permanent, fully-paid sub-license to sell Product in the Territory, and (b) ownership of the Trademark in the Territory. The purchase price for such option, if successfully executed, shall be an amount equal to one times the average annual Net Sales of such Product from 1999 until the date Lil' Drug Store Products exercises the option; provided, however, such purchase price shall not be less than the average annual Net Sales of such Product in 1999.

16. ARBITRATION.

(a) ARBITRATION. In the event of any dispute (a "Dispute") between the parties hereto subsequent to the Effective Date with respect to the breach, interpretation or enforcement of this Agreement, such dispute shall be resolved by binding arbitration in accordance with the commercial arbitration rules of the American Arbitration Association ("AAA"). Notwithstanding the foregoing, the parties intend to depart from the AAA commercial arbitration rules to the extent any of the following provisions conflict with such rules.

(b) PANEL. Any arbitration shall take place before a panel of three (3) arbitrators (the "Panel"). The Panel shall be selected in accordance with the AAA's procedures for selecting an arbitration Panel, provided, that the Panel shall include one certified public accountant and one transactional lawyer, each of whom shall have had at least ten (10) years experience in his or her respective field, and at least three (3) years of arbitration experience. If any arbitrator on the Panel neglects or refuses to act or is or becomes incapable of acting, or dies before the Panel shall have made its award, and the parties fail to agree or concur in the appointment of another arbitrator, either party may serve on the other a notice in writing requiring him to agree and concur in the appointment of another arbitrator, and if such appointment is not made within twenty (20) days from the service of said notice, then the remaining arbitrators shall have power on the request in writing of either party to appoint another arbitrator who shall have the like authority to act in the arbitration and make an award and the like powers in all respects as if he had been appointed by the parties.

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(c) BINDING EFFECT. Each of the parties agrees that the decision of the Panel shall be final and binding on the parties hereto and, provided diversity or other federal jurisdiction exists, the parties hereby consent to the entry of final judgment thereon in the United States District Court for the Southern District of New York, and to the issuance of execution on the judgment. The award may be appealed only to the court in which judgment on the award is required to be entered and only to the extent the award contains material errors of applicable law, is arbitrary or capricious, or was fraudulently obtained. If the parties cannot meet the applicable requirements for federal jurisdiction, the parties agree to the entry of judgment in the New York Supreme Court located in New York City, New York, and to the issuance of execution on such judgment. The parties hereto hereby consent to the jurisdiction of such court (i.e., such federal court, or, in the event federal jurisdiction does not exist, such state court) in reference to any matter arising out of the arbitration or this Agreement including but not limited to confirmation of any arbitration award and enforcement thereof by entry of judgment thereon or by any other legal remedy. As to any Dispute which under the terms hereof is made subject to arbitration, no suit at law or in equity based on such Dispute shall be instituted by either party hereto other than to enforce the award of the Panel. If any controversy shall arise after the award as to whether the award or any part thereof has been complied with, such controversy shall be determined by the same Panel.

(d) EVIDENCE. The Panel shall not be bound by strict rules of evidence and may give such right to evidence as may seem right and proper to it. The Panel shall schedule a pre-hearing conference to resolve procedural matters, arrange for the exchange of information, obtain stipulations, and narrow the issues. The parties will submit proposed discovery schedules to the Panel at the pre-hearing conference. The scope and duration of discovery will be within the sole discretion of the Panel. Unresolved discovery disputes may be brought to the attention of the chair of the arbitration panel and may be disposed of by the chair of the panel. The Panel shall have the discretion to order a pre-hearing exchange of information by the parties, including, without limitation, production of requested documents, exchange of summaries of testimony of proposed witnesses, and examination by deposition of parties and third-party witnesses. This discretion shall be exercised in favor of discovery reasonable under the circumstances. The arbitration shall be conducted in New York, New York. Any party may be represented by counsel or other authorized representative. In rendering a decision(s), the Panel shall determine the rights and obligations of the parties according to the substantive and procedural laws of New York and the terms and provisions of this Agreement. The Panel's decision shall be based on the evidence introduced at the hearing, including all logical and reasonable inferences therefrom. The Arbitrator may make any determination, and/or grant any remedy or relief that is just and equitable, subject to the express provisions of this Agreement. The Panel shall have power to award and direct that the parties or any of them shall execute such releases, conveyances, assurances, and do things as the Panel shall think fit and such releases, conveyances, assurances and things shall be executed and done accordingly. The Panel shall have the authority to proceed ex parte in case of the nonattendance of either of the parties or of their witnesses after thirty (30) days prior notice in writing by the Panel given to the parties respectively or their respective attorneys or agents notifying the time and place of meeting to proceed with the reference. Any provisional remedy that would be available from a court of law shall be available from the arbitrator to the parties to this Agreement pending arbitration.

(e) WAIVER OF CONSEQUENTIAL DAMAGES. The Panel shall have no authority to award consequential damages, punitive damages, and all other damages not measured by the prevailing party's actual damages, and each party hereby waives all claims to same. The Panel

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may not in any event make any ruling, finding or award that does not conform to the terms and conditions of the Agreement. Liabilities for taxes are direct damages.

(f) DISCLOSURE. Except to the extent disclosure, filing, reporting or announcement thereof is required by law, including by any rules or regulations of any applicable governmental, regulatory or stock exchange agency or authority, neither a party nor an arbitrator may disclose the existence, content or results of any arbitration hereunder without the prior written consent of both parties, except to the extent that the recordation of a final judgment causes such matters to become public.

17. NOTICES. All notices required hereunder shall be in writing and shall be deemed to be properly given if sent by air courier to the party to be notified at the address set forth on page 1 hereof, or at such other latest address as either party may hereafter designate in writing to the other; provided that a copy of each notice to be sent to Columbia hereunder shall also be sent by the same means to William J. Bologna, Chairman of the Board, Columbia Laboratories, Inc., 2875 N.E. 191st St., Suite 400, Aventura, Florida 33180; and further provided that a copy of each notice set to Lil' Drug Store Products hereunder shall also be sent by the same means to Chris DeWolf, 1201 Continental Place NE, Cedar Rapids, Iowa 52402. The date of service of any notice to sent by air courier shall be the date of receipt.

18. TAX. All taxes levied on account of any payments accruing under this Agreement that constitute income to Columbia, shall be the obligation of Columbia, and if provision is made in law or regulation for withholding, such tax shall be deducted from any payment then due, paid to the proper taxing authority, and receipt for payment of the tax secured and promptly sent to Columbia.

19. INDEPENDENT CONTRACTORS. The relationship of the parties under this Agreement is that of independent contractors. Neither party shall be deemed to be the agent of the other and neither is authorized to take any action binding upon the other.

20. ENTIRE AGREEMENT; MODIFICATION. This Agreement, including the Schedules hereto, contains the entire understanding between the parties hereto relating to the subject matter hereof, there being no terms and conditions other than those set forth herein, and it supersedes all prior agreements, written or oral, between the parties hereto with respect to the matters covered hereunder. This Agreement may not be modified, altered or otherwise changed other than by an instrument in writing, duly executed by each of the parties hereto.

21. SEVERABILITY. If any provision of this Agreement should be or becomes fully or partly invalid or unenforceable for any reason whatsoever or should be adjudged to violate any applicable law, this Agreement is to be considered divisible as to such provision and such provision is deemed to be deleted from this Agreement, and the remainder of this Agreement shall be valid and binding as if such provision were not included herein; provided, however, that this Agreement is not rendered fundamentally different in its content or effect.

22. EFFECT OF HEADINGS. The headings for the sections and paragraphs of this Agreement are to facilitate reference only, do not form a part of this Agreement, and shall not in any way affect the interpretation hereof.

23. CHOICE OF LAW. This Agreement and performance hereof shall be construed and governed by the laws of the State of New York and of the United States. Any dispute, controversy, claim or difference arising between the parties out of, relating to, or in connection


with this Agreement shall be submitted to the jurisdiction of the courts sitting in the State of Iowa or the State of New York, at the option of the party filing such action.

24. NO WAIVER. No delay or omission or failure to exercise any right or remedy provided for herein shall be deemed to be a waiver thereof or acquiescence in the event giving rise to such right or remedy.

25. COUNTERPARTS. This Agreement may be executed in any number of counterparts and by the different parties hereto on separate counterparts, each of which, when so executed shall be deemed an original, but all such counterparts shall constitute but one and the same instrument.

26. FURTHER ASSURANCES. Columbia and Lil' Drug Store Products each agree to produce or execute such other documents or agreements as may be necessary or desirable for the execution and implementation of this Agreement and the consummation of the transactions contemplated hereby.

27. FORCE MAJEURE. No failure or omission by a party hereto in the performance of any obligation of this Agreement shall be deemed a breach of this Agreement nor shall it create any liability if the same shall arise from any cause or causes beyond the control of the party, including, but not limited to, the following, which, for the purposes of this Agreement, shall be regarded as beyond the control of the party in question: acts of God, acts or omissions of any government, any rules, regulations, or orders issued by any governmental authority or any officer, department, agency, or instrumentality thereof, fire, storm, flood, earthquake, accident, war, rebellion, insurrection, riot, invasion, strikes, lockouts; provided however, that the party so affected shall promptly advise the other party of the existence of such causes of nonperformance, shall use its best efforts to avoid or remove such causes of nonperformance and shall continue hereunder wit the utmost dispatch whenever such causes are removed.

28. PERFORMANCE BY AFFILIATES. The parties agree that certain of their rights and obligations under this Agreement may not be carried out by one or more of their Affiliates; provided, however, that each party shall remain responsible for the acts and omission of its Affiliates. The parties further understand and agree that no such Affiliate is a party to this Agreement, and, except as contemplated by this Agreement, is not the agent of such party for purposes hereof, is not authorized to bind such party and cannot enter into amendments to this Agreement, which can only be made in accordance with the terms of Section 20 hereof.

IN WITNESS WHEREOF, the parties hereto have set their hands as of the day and year first above written.

COLUMBIA LABORATORIES, INC.                LIL' DRUG STORE PRODUCTS, INC.

By:/S/ WILLIAM J. BOLOGNA                  By:/S/ DENNIS OLDORF
  -----------------------                     -----------------
  William J. Bologna                          Dennis Oldorf
  Chairman of the Board                       Chairman of the Board

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ARTICLE 5


PERIOD TYPE 3 MOS
FISCAL YEAR END DEC 31 2000
PERIOD START JAN 01 2000
PERIOD END MAR 31 2000
CASH 5,501,774
SECURITIES 0
RECEIVABLES 2,558,387
ALLOWANCES 119,829
INVENTORY 1,428,843
CURRENT ASSETS 10,087,871
PP&E 2,508,705
DEPRECIATION 1,605,996
TOTAL ASSETS 17,354,256
CURRENT LIABILITIES 2,665,199
BONDS 0
PREFERRED MANDATORY 0
PREFERRED 59
COMMON 304,126
OTHER SE 4,689,057
TOTAL LIABILITY AND EQUITY 17,354,256
SALES 2,989,930
TOTAL REVENUES 2,989,930
CGS 1,219,848
TOTAL COSTS 1,219,848
OTHER EXPENSES 2,964,410
LOSS PROVISION 0
INTEREST EXPENSE 188,838
INCOME PRETAX (1,361,696)
INCOME TAX 0
INCOME CONTINUING (1,361,696)
DISCONTINUED 0
EXTRAORDINARY 0
CHANGES 0
NET INCOME (1,361,696)
EPS BASIC (0.05)
EPS DILUTED (0.05)