U.S. SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

Form 8-K

Current Report Pursuant to Section 13 or 15(d) of
the Securities Exchange Act of 1934


Date of Report (Date of earliest event reported):
January 17, 2011

SUNSHINE BIOPHARMA, INC.
(Exact name of small business issuer as specified in its charter)

Colorado
000-0-52898
20-5566275
(State or other jurisdiction
of incorporation)
(Commission File Number)
(IRS Employer ID No.)

2015 Peel Street
5 th Floor
Montreal, Quebec, Canada H3A 1T8
 (Address of principal executive offices)


( 514) 764-9698
  (Issuer's Telephone Number)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

[ ] Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 
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Item 1.01 Entry into a Material Definitive Agreement.

Effective January 17, 2011, we executed a Research Agreement (the “Agreement”) with The Research Foundation of the State University of New York, a not-for-profit educational corporation duly organized and existing under the laws of the State of New York, acting for and on behalf of Binghamton University.  The purpose of the Agreement is to memorialize the terms of our working together with Binghamton University to conduct the necessary research and development to advance our lead compound, Adva-27a (or its derivative, Adva-32a) through various stages of preclinical development, animal studies and Phase I clinical trials for breast cancer and prostate cancer.  The Agreement shall be in force for a period of three (3) years from the Effective Date and shall be renewed automatically for additional one (1) year periods until the Project is completed, unless the research is completed prior to the initial three year term of the Agreement.  The relationship between us and Binghamton University is exclusive in the United States.

All of the work in respect of the project to be performed within the framework of the Agreement shall be financed by the parties working together to secure grants by acting as co-applicants and submitting funding applications to various Federal, State, local and private sources.  The Agreement is subject to the procurement of funding.  In the event that said funding is not obtained or is subsequently disrupted, cancelled or otherwise found to be insufficient to complete the project, the Agreement shall terminate at that time.  As of the date of this Report, no definitive agreement is in place to provide this funding and there can be no assurances that such funding will be secured in an amount sufficient to conduct the project, or at all, but based upon existing discussions our management is confident that the parties to the Agreement will secure such funding in the near future.

The Agreement also provides for Binghamton University to have an option to continue the development of Adva-27a and/or Adva-32a through Phase II, Phase III and other clinical trials until full FDA approval for breast cancer and prostate cancer is obtained, on terms to be mutually agreed in the future.

A copy of the Agreement is attached hereto and incorporated herein as if set forth as Exhibit 10.4

Item 7.01 Regulation FD Disclosure

Our Press Release relating to the Agreement is attached as Exhibit 99.2 and is hereby incorporated.


 
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Item 9.01 Financial Statements and Exhibits

(b) Exhibits.  The following exhibits are included in this report:

No.
 
Description
     
10.4
 
Research Agreement between Sunshine Biopharma, Inc. and The Research Foundation of the State University of New York
     
99.2
 
Press Release Dated January 21, 2010


 
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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.


Dated:  January 20, 2011
 
SUNSHINE BIOPHARMA, INC.
(Registrant)
 
By: s/Dr. Steve N. Slilaty
    Dr. Steve N. Slilaty
    Chief Executive Officer




 
 
 
EXHIBIT 10.4
 
 

 
 
 

 
 
 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
 
 

 
EXHIBIT 99.2
 


For Immediate Release
January 21, 2011

 
SUNSHINE BIOPHARMA AND BINGHAMTON UNIVERSITY (STATE UNIVERSITY OF NEW YORK) ENTER INTO RESEARCH AGREEMENT

Parties to Work Together for Clinical Studies on
Breast and Prostate Cancer Drug

 
Montreal, Quebec, Canada-(Canada Newswire)-Sunshine Biopharma, Inc. (OTCBB Ticker Symbol: SBFM) a development stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has executed an agreement with The Research Foundation of the State University of New York (SUNY), acting for and on behalf of Binghamton University (Binghamton, NY).  As a result, the parties will begin conducting the necessary research and development to advance Sunshine’s lead compound, Adva-27a through various stages of preclinical development and Phase I clinical trials for breast cancer and prostate cancer.  The Agreement shall be in force for a period of three (3) years from the Effective Date and shall be renewed automatically for additional one (1) year periods until the Project is completed, unless the research is completed prior to the initial three year term of the Agreement.  Adva-27a is a small molecule that inhibits Topoisomerase II, an enzyme found in abundance in Multi-Drug Resistant breast cancer as well as in other types of aggressive cancer.
 
Dr. Steve Slilaty, Sunshine’s President and CEO, stated “we are very excited to sign the agreement with Binghamton University.  This is the next step for us and we believe Adva-27a is a much more effective inhibitor of Topoisomerase II without the risks of toxicity or significant adverse side effects.  Data published in our issued and pending patent applications have shown that Adva-27a is three times more effective in arresting cancer cell growth than its current market competitor.”   Dr. Slilaty also stated “We anticipate completion by the first half of 2012 and if things go as we expect, we anticipate Adva-27a to be available for “compassionate-use” by the end of the trial.  We are excited by the challenges ahead and the potential to make a difference in the length and quality of life for many cancer patients throughout the world”.
 

 
 

 

Dr. Susannah Gal, Associate Professor in the Department of Biological Sciences at Binghamton University, stated “I look forward to pursuing laboratory studies and coordinating clinical trials to better understand the action of this exciting new drug.  If these studies pan out as expected, this drug could have a dramatic positive impact in the clinic.  As a cancer survivor myself, it is gratifying to potentially help those facing the ravages of this disease with our work on this compound.”

Safe Harbor Forward-Looking Statements
 
To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.

For Additional Information Contact:
 
CEOcast, Inc.
Dan Schustack, 212-732-4300
Investor Relations
dschustack@ceocast.com