UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C.  20549



FORM 8-K



CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934



Date of report (Date of earliest event reported)    May 6, 2013



OphthaliX Inc.

(Exact Name of Registrant as Specified in its Charter)



Delaware

000-52545

88-0445167

(State or Other Jurisdiction

of Incorporation)

(Commission File Number)

(IRS Employer

Identification No.)



10 Bareket St, Petach Tikva, Israel

49170

(Address of Principal Executive Offices)

(Zip Code)



Registrant’s telephone number, including area code:   +(972) 39241114



Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:


        .

Written communications pursuant to Rule 425 under the Securities Act


        .

Soliciting material pursuant to Rule 14a-12 under the Exchange Act


        .

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act


        .

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act






Item 3.02

Unregistered Sales of Equity Securities.


On May 9, 2013, the Board of Directors approved the grant of the following options (the “ Options ”), to acquire shares of Common Stock of the Company in accordance with the terms of the 2012 Stock Incentive Plan, as amended (the “ Plan ”):


·

117,500 options to Motti Farbstein (58,750 to vest immediately and the remaining 58,750 to vest quarterly for three years).


The exercise price of the Options is $1.29 and the Options expire ten years from the grant date.  The Options were granted without registration under the Securities Act by reason of the exemption from registration afforded by the provisions of Section 4(a)(5) and/or Section 4(a)(2) thereof, and Rule 506 promulgated thereunder, as a transaction by an issuer not involving any public offering.  The recipient of the Options was an accredited investor as defined in Rule 501(a) of Regulation D promulgated by the SEC.  The securities issued in this transaction were not registered under the Securities Act and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.


The disclosure set forth in Item 5.02 of this Current Report on Form 8-K is incorporated by reference in this Item 3.02.


Item 5.02

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.


On May 9, 2013, the Board of Directors approved the grant of the following options (the “ Management Options ”), subject to shareholder approval in case of the Directors of the Company (Dr. Pnina Fishman, Dr. Ilan Cohn and Guy Regev), to acquire shares of Common Stock of the Company in accordance with the terms of the Plan:


·

940,000 options to Dr. Pnina Fishman, our Chairman (470,000 to vest immediately and the remaining 470,000 to vest quarterly for three years);

·

235,000 options to Dr. Ilan Cohn, one of our directors (117,500 to vest immediately and the remaining 117,500 to vest quarterly for three years);

·

235,000 options to Guy Regev, one of our directors (117,500 to vest immediately and the remaining 117,500 to vest quarterly for three years);

·

235,000 options to Ronen Kantor, our Secretary (117,500 to vest immediately and the remaining 117,500 to vest quarterly for three years);

·

117,500 options to Itay Weinstein, our Chief Financial Officer (58,750 to vest immediately and the remaining 58,750 to vest quarterly for three years); and


The exercise price of the Management Options is $1.29 and the Management Options expire ten years from the grant date.  The Management Options were granted without registration under the Securities Act by reason of the exemption from registration afforded by the provisions of Section 4(a)(5) and/or Section 4(a)(2) thereof, and Rule 506 promulgated thereunder, as a transaction by an issuer not involving any public offering.  Each recipient of the Management Options was an accredited investor as defined in Rule 501(a) of Regulation D promulgated by the SEC. The securities issued in this transaction were not registered under the Securities Act and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.




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Item 5.03

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.


On May 6, 2013, the Board of Directors approved several amendments to the Bylaws of the Company. The amendments are summarized as follows:


·

Section 2.2 of Article II of the Bylaws titled “Removal; Resignation” is amended to read as follows:


Any director or the entire Board of Directors may be removed, with or without cause but only with cause, by the holders of a majority of the shares then entitled to vote at an election of directors.  Any director may resign at any time upon notice given in writing to the Corporation.  A resignation is effective when the resignation is delivered unless the resignation specifies a later effective date or an effective date determined upon the happening of an event or events.  A resignation that is conditioned upon the director failing to receive a specified vote for reelection as a director may provide that it is irrevocable.


·

Section 4.1 of Article IV of the Bylaws titled “Generally” is amended to read as follows:


The officers of the Corporation shall consist of a Chairman of the Board, a Chief Executive Officer or a President, a Secretary, and a Treasurer.  The officers of the Corporation may consist of a Chief Financial Officer, one or more Vice Presidents, a Controller, and the other officers as may from time to time be appointed by the Board of Directors.  Officers shall be elected by the Board of Directors, which shall consider that subject at its first meeting after every annual meeting of stockholders.  Each officer shall hold office until his or her successor is elected and qualified or until his or her earlier resignation or removal.  Any number of offices may be held by the same person.  The salaries of officers elected by the Board of Directors shall be fixed from time to time by the Board of Directors or by the officers as may be designated by resolution of the Board.


·

Section 5.1 of Article V of the Bylaws titled “Certificates of Stock” be amended to read as follows:


Each stockholder shall be entitled to a certificate signed by, or in the name of the Corporation by, the Chairman of the Board, the Vice Chairman of the Board, the Chief Executive Officer, President or Vice President , and by the Secretary or an Assistant Secretary, or the Treasurer or an Assistant Treasurer, certifying the number of shares owned by him or her unless the Board of Directors provides by resolution that some or all of any or all classes or series of stock shall be uncertificated shares.  Any or all of the signatures on the certificate may be by facsimile.


·

A new section designated as Article IX of the Bylaws was added to the Bylaws and the remaining Articles are renumbered as applicable:


ARTICLE IX

Forum for Adjudication of Disputes


Unless the Corporation consents in writing to the selection of an alternative forum, the sole and exclusive forum for (i) any derivative action or proceeding brought on behalf of the Corporation, (ii) any action asserting a claim of breach of a fiduciary duty owed by any director, officer or other employee of the Corporation to the Corporation or the Corporation’s stockholders, (iii) any action asserting a claim arising pursuant to any provision of the Delaware General Corporation Law, or (iv) any action asserting a claim governed by the internal affairs doctrine shall be a state or federal court located within the state of Delaware, in all cases subject to the court’s having personal jurisdiction over the indispensible parties named as defendants. Any person or entity purchasing or otherwise acquiring any interest in shares of capital stock of the Corporation shall be deemed to have notice of and consented to the provisions of this Article IX.



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The Board of Directors will seek shareholder ratification of the new Article IX in a proxy statement to be mailed to the shareholders.  A copy of the Bylaws, as amended is attached as an exhibit hereto.


Item 5.07

Submission of Matters to a Vote of Security Holders.


On May 9, 2013, the Company held its annual meeting of stockholders (the “ Annual Meeting ”).  The matters voted upon were: (i) the re-election of Dr. Pnina Fishman, Dr. Ilan Cohn, Guy Regev, and Dr. Roger Kornberg as directors, and (ii) the ratification of the appointment of Kost Forer Gabbay & Kasierer, a member of Ernst & Young Global (“ Ernst & Young ”), as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2013.  There were no abstentions or broker non-votes for either matter voted upon at the Annual Meeting.


Each of the nominees for director was reelected at the Annual Meeting and the results of the voting for the members of the Board of Directors are set forth below:


Nominees

Votes For

Votes Against

Abstain

Pnina Fishman

38,534,631

0

0

Ilan Cohn

38,534,631

0

0

Guy Regev

38,534,631

0

0

Roger Kornberg

38,534,631

0

0


The proposal to ratify the appointment of Ernst & Young as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2013, was approved.  The results of the voting were as follows:


Votes For

Votes Against

Abstain

38,534,631

0

0


Item 8.01

Other Events.


On May 6, 2013, the Board of Directors adopted an Insider Trading Policy, a Foreign Corrupt Practices Act Policy, a Code of Ethics, and a Code of Conduct.  The Code of Ethics and the Code of Conduct will be available on the Company’s corporate website at www.ophthalix.com.


On May 10, 2013, the Company issued a press release in regard to validation of the use of A3 Adenosine Receptor Agonists for lowering intra ocular pressure and for the treatment of glaucoma.  A copy of the press release is included with this report.


Item 9.01

Financial Statements and Exhibits


(d) Exhibits


3.1

Bylaws, as amended

99.1

Insider Trading Policy

99.2

Press Release dated May 10, 2013




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SIGNATURES


Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.



OphthaliX Inc.




Date:  May 10, 2013

By: /s/ Barak Singer

Barak Singer, Chief Executive Officer




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Exhibit 3.1


BYLAWS

OF

OPHTHALIX INC.


ARTICLE I

Stockholders


Section 1.1.

Annual Meeting.


An annual meeting of the stockholders for the election of directors to succeed those whose terms expire and for the transaction of such other business as may properly come before the meeting shall be held at the place, if any, on the date, and at the time as the Board of Directors shall each year fix, which date shall be within 13 months of the last annual meeting of stockholders.


Section 1.2.

Advance Notice of Nominations and Proposals of Business.


a)

Nominations of persons for election to the Board of Directors and the proposal of business to be transacted by the stockholders may be made at an annual meeting of stockholders (i) pursuant to the Corporation’s proxy materials with respect to such meeting, (ii) by or at the direction of the Board of Directors, or (iii) by any stockholder (or stockholders acting jointly) of record of the Corporation (the “Record Stockholder”) at the time of the giving of the notice required in the following paragraph, who is entitled to vote at the meeting, who has complied with the notice procedures set forth in this section, and who owns more than 5% of the outstanding common stock of the Corporation.  For the avoidance of doubt, the foregoing clause (iii) shall be the exclusive means for a stockholder to make nominations or propose business (other than business included in the Corporation’s proxy materials pursuant to Rule 14a-8 under the Securities Exchange Act of 1934, as amended (such act, and the rules and regulations promulgated thereunder, the “Exchange Act”)) at an annual meeting of stockholders.


b)

For nominations or business to be properly brought before an annual meeting by a Record Stockholder pursuant to clause (iii) of the foregoing paragraph, (i) the Record Stockholder must have given timely notice thereof in writing to the Secretary of the Corporation, and (ii) any such business must be a proper matter for stockholder action under Delaware law.  To be timely, a Record Stockholder’s notice shall be received by the Secretary at the principal executive offices of the Corporation not less than 45 or more than 75 days prior to the one-year anniversary of the date on which the Corporation first mailed its proxy materials for the preceding year’s annual meeting of stockholders; provided, however, that, subject to the last sentence of this paragraph (b), if the meeting is convened more than 30 days prior to or delayed by more than 30 days after the anniversary of the preceding year’s annual meeting, or if no annual meeting was held in the preceding year, notice by the Record Stockholder to be timely must be so received not later than the close of business on the later of (i) the 90th day before such annual meeting or (ii) the 10th day following the day on which public announcement of the date of such meeting is first made.  Notwithstanding anything in the preceding sentence to the contrary, in the event that the number of directors to be elected to the Board of Directors is increased and there has been no public announcement naming all of the nominees for director or indicating the increase in the size of the Board of Directors made by the Corporation at least 10 days before the last day a Record Stockholder may deliver a notice of nomination in accordance with the preceding sentence, a Record Stockholder’s notice required by this bylaw shall also be considered timely, but only with respect to nominees for any new positions created by such increase, if it shall be received by the Secretary at the principal executive offices of the Corporation not later than the close of business on the 10th day following the day on which such public announcement is first made by the Corporation.  In no event shall an adjournment, or postponement of an annual meeting for which notice has been given, commence a new time period for the giving of a Record Stockholder’s notice.


c)

Such Record Stockholder’s notice shall set forth:


1)

if such notice pertains to the nomination of directors, as to each person whom the Record Stockholder proposes to nominate for election or reelection as a director all information relating to such person as would be required to be disclosed in solicitations of proxies for the election of such nominees as directors pursuant to Regulation 14A under the Exchange Act, and such person’s written consent to serve as a director if elected;


2)

as to any business that the Record Stockholder proposes to bring before the meeting, a brief description of such business, the reasons for conducting such business at the meeting and any material interest in such business of such Record Stockholder and the beneficial owner, if any, on whose behalf the proposal is made; and





3)

as to (a) the Record Stockholder giving the notice and (b) the beneficial owner, if any, on whose behalf the nomination or proposal is made each, (a “party”):


i.

the name and address of each such party;


ii.

(A) the class, series, and number of shares of the Corporation that are owned, directly or indirectly, beneficially and of record by each such party, (B) any option, warrant, convertible security, stock appreciation right, or similar right with an exercise or conversion privilege or a settlement payment or mechanism at a price related to any class or series of shares of the Corporation or with a value derived in whole or in part from the value of any class or series of shares of the Corporation, whether or not such instrument or right shall be subject to settlement in the underlying class or series of capital stock of the Corporation or otherwise (a “Derivative Instrument”) directly or indirectly owned beneficially by each such party, and any other direct or indirect opportunity to profit or share in any profit derived from any increase or decrease in the value of shares of the Corporation, (C) any proxy, contract, arrangement, understanding, or relationship pursuant to which either party has a right to vote, directly or indirectly, any shares of any security of the Corporation, (D) any short interest in any security of the Corporation held by each such party (for purposes of this Section 1.2(c), a person shall be deemed to have a short interest in a security if such person directly or indirectly, through any contract, arrangement, understanding, relationship or otherwise, has the opportunity to profit or share in any profit derived from any decrease in the value of the subject security), (E) any rights to dividends on the shares of the Corporation owned beneficially directly or indirectly by each such party that are separated or separable from the underlying shares of the Corporation, (F) any proportionate interest in shares of the Corporation or Derivative Instruments held, directly or indirectly, by a general or limited partnership in which either party is a general partner or, directly or indirectly, beneficially owns an interest in a general partner and (G) any performance-related fees (other than an asset-based fee) that each such party is directly or indirectly entitled to based on any increase or decrease in the value of shares of the Corporation or Derivative Instruments, if any, as of the date of such notice, including without limitation any such interests held by members of each such party’s immediate family sharing the same household (which information set forth in this paragraph shall be supplemented by such stockholder or such beneficial owner, as the case may be, not later than ten (10) days after the record date for the meeting to disclose such ownership as of the record date); and


iii.

any other information relating to each such party that would be required to be disclosed in a proxy statement or other filings required to be made in connection with solicitations of proxies for, as applicable, the proposal and/or for the election of directors in a contested election pursuant to Section 14 of the Exchange Act.


d)

A person shall not be eligible for election or re-election as a director at an annual meeting unless (i) the person is nominated by a Record Stockholder in accordance with clause (iii) of Section 1.2(a) or (ii) the person is nominated by or at the direction of the Board of Directors.  Only such business shall be conducted at an annual meeting of stockholders as shall have been brought before the meeting in accordance with the procedures set forth in this section.  The chair of the meeting shall have the power and the duty to determine whether a nomination or any business proposed to be brought before the meeting has been made in accordance with the procedures set forth in these Bylaws and, if any proposed nomination or business is not in compliance with these Bylaws, to declare that such defectively proposed business or nomination shall not be presented for stockholder action at the meeting and shall be disregarded.


e)

Only such business shall be conducted at a special meeting of stockholders as shall have been brought before the meeting by or at the direction of the Board of Directors.  The notice of such special meeting shall include the purpose for which the meeting is called.  Nominations of persons for election to the Board of Directors may be made at a special meeting of stockholders at which directors are to be elected (a) by or at the direction of the Board of Directors or (b) by any stockholder of record at the time of giving of notice provided for in this paragraph, who shall be entitled to vote at the meeting and who delivers a written notice to the Secretary setting forth the information set forth in Section 1.2(c)(1) and (3) of this Article I.  Nominations by stockholders of persons for election to the Board of Directors may be made at such a special meeting of stockholders only if such stockholder of record’s notice required by the preceding sentence shall be received by the Secretary at the principal executive offices of the Corporation not later than the close of business on the later of the 90th day prior to such special meeting or the 10th day following the day on which public announcement is first made of the date of the special meeting and of the nominees proposed by the Board of Directors to be elected at such meeting.  In no event shall an adjournment, or postponement of a special meeting for which notice has been given, commence a new time period for the giving of a stockholder of record’s notice.  A person shall not be eligible for election or reelection as a director at a special meeting unless the person is nominated (i) by or at the direction of the Board of Directors or (ii) by a stockholder of record in accordance with the notice procedures set forth in this Article I.



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f)

For purposes of these Bylaws, “public announcement” shall mean disclosure in a press release reported by the Dow Jones News Service, Associated Press or a comparable national news service or in a document publicly filed by the Corporation with the Securities and Exchange Commission pursuant to Section 13, 14 or 15(d) of the Exchange Act.


g)

Notwithstanding the foregoing provisions of this Section 1.2, a stockholder shall also comply with all applicable requirements of the Exchange Act and the rules and regulations thereunder with respect to matters set forth in this Section 1.2.  Nothing in this Section 1.2 shall be deemed to affect any rights of stockholders to request inclusion of proposals in the Corporation’s proxy statement pursuant to Rule 14a-8 under the Exchange Act.


Section 1.3.

Special Meetings; Notice.


Special meetings of stockholders shall be called as provided in the Certificate of Incorporation.  Upon request in writing sent by registered or certified mail to the Chairman of the Board, the President, or Chief Executive Officer by any stockholder or stockholders entitled to call a special meeting of stockholders, the Board of Directors shall determine a place and time for such meeting, which time shall be not less than 90 nor more than 100 days after the receipt and determination of the validity of such request, and a record date for the determination of stockholders entitled to vote at such meeting in the manner set forth in Section 5.5 hereof.  Following such receipt and determination, it shall be the duty of the Secretary to cause notice to be given to the stockholders entitled to vote at such meeting, in the manner set forth in Section 1.4 hereof, that a meeting will be held at the time and place so determined.  Notice of every special meeting shall state the purpose of the meeting and the business conducted at a special meeting of stockholders shall be limited to the business set forth in the notice of meeting.  The Board of Directors may postpone or reschedule any previously called special meeting.


Section 1.4.

Notice of Meetings.


a)

Notice of the place, if any, date and time of all meetings of the stockholders, and the means of remote communications, if any, by which stockholders and proxyholders may be deemed present in person and vote at such meeting, and, in the case of all special meetings of stockholders, the purpose of the meeting, shall be given, not less than 10 nor more than 60 days before the date on which the meeting is to be held, to each stockholder entitled to vote at the meeting, except as otherwise provided in these bylaws or required by law (meaning in these bylaws, as required from time to time by the Delaware General Corporation Law or the Corporation’s Certificate of Incorporation).


b)

When a meeting is adjourned to another time or place, notice need not be given of the adjourned meeting if the time and place, if any, thereof and the means of remote communication, if any, by which stockholder and proxyholders may be deemed to be present in person of such adjourned meeting are announced at the meeting at which the adjournment is taken; provided, however, that if the date of any adjourned meeting is more than 30 days after the date for which the meeting was originally noticed, or if a new record date is fixed for the adjourned meeting, notice of the place, if any, date and time of the adjourned meeting and the means of remote communications, if any, by which stockholders and proxyholders may be deemed to be present in person and vote at such adjourned meeting, shall be given in conformity herewith.  At any adjourned meeting, any business may be transacted that might have been transacted at the original meeting.


Section 1.5.

Quorum.


a)

At any meeting of the stockholders, the holders of shares of stock of the Corporation entitled to cast at least 33 percent (33.33%) of the total votes entitled to be cast by the holders of all outstanding capital stock of the Corporation, present in person or by proxy, shall constitute a quorum for all purposes, unless or except to the extent that the presence of a larger number is required by law.  Where a separate vote by one or more classes or series is required, the holder of shares entitled to cast 33 percent (33.33%) of the total votes entitled to be cast by the holders of the shares of the class or classes or series, present in person or represented by proxy, shall constitute a quorum entitled to take action with respect to that vote on that matter.


b)

If a quorum shall fail to attend any meeting, the chair of the meeting may adjourn the meeting to another place, if any, date and time.



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Section 1.6.

Organization.


The Chairman of the Board or, in his or her absence, the person whom the Board of Directors designates or, in the absence of that person or the failure of the Board of Directors to designate a person, the Chief Executive Officer of the Corporation or, in his or her absence, the person chosen by the holders of a majority of the shares entitled to vote who are present, in person or by proxy, shall call to order any meeting of the stockholders and act as chair of the meeting.  In the absence of the Secretary of the Corporation, the secretary of the meeting shall be the person the chair appoints.


Section 1.7.

Conduct of Business.


The chair of any meeting of stockholders shall determine the order of business and the rules of procedure for the conduct of the meeting, including the manner of voting and the conduct of discussion as the chair determines to be in order.  The chair shall have the power to adjourn the meeting to another place, if any, date and time.  The date and time of the opening and closing of the polls for each matter upon which the stockholders will vote at the meeting shall be announced at the meeting.


Section 1.8.

Proxies; Inspectors.


a)

At any meeting of the stockholders, every stockholder entitled to vote may vote in person or by proxy authorized by an instrument in writing or by a transmission permitted by law filed in accordance with the procedure established for the meeting.  Any copy, facsimile telecommunication or other reliable reproduction of the writing or transmission created pursuant to this Section 1.8 may be substituted or used in lieu of the original writing or transmission that could be used, provided that the copy, facsimile telecommunication or other reproduction shall be a complete reproduction of the entire original writing or transmission.


b)

The Board of Directors shall, in advance of any meeting of stockholders, appoint one or more inspectors to act at the meeting and make a written report thereof.  The Corporation may designate one or more persons as alternate inspectors to replace any inspector who fails to act.  If no inspector or alternate is able to act at a meeting of stockholders, the person presiding at the meeting may, and to the extent required by law, shall, appoint one or more inspectors to act at the meeting.  Each inspector, before entering upon the discharge of his duties, shall take and sign an oath faithfully to execute the duties of inspector with strict impartiality and according to the best of his or her ability.  The inspectors may appoint or retain other persons or entities to assist the inspectors in the performance of the duties of inspectors.


Section 1.9.

Voting.


All elections of directors shall be determined by a plurality of the votes cast, and except as otherwise required by law or these bylaws, all other matters shall be determined by a majority of the votes cast on the matter affirmatively or negatively.


Section 1.10.

 Stock List.


a)

A complete list of stockholders entitled to vote at any meeting of stockholders, arranged in alphabetical order for each class of stock and showing the address of each such stockholder and the number of shares registered in his or her name, shall be open to the examination of any such stockholder, for any purpose germane to the meeting, during ordinary business hours for a period of at least 10 days prior to the meeting as required by law.


b)

The stock list shall also be open to the examination of any such stockholder during the whole time of the meeting as provided by law.  The Corporation may look to this list as the sole evidence of the identity of the stockholders entitled to vote at the meeting and the number of shares held by each of them.


Section 1.11.

Written Consents.


Every written consent shall bear the date of signature of each stockholder who signs the consent and no written consent shall be effective to take the corporate action referred to therein unless, within 60 days of the earliest dated consent received in accordance with applicable law, a written consent or consents signed by a sufficient number of holders to take such action are delivered to the Corporation as required by law.



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ARTICLE II

Board of Directors


Section 2.1.

Number, Election, Term and Qualifications of Directors.


a)

Subject to the special right of the holders of any class or series of stock to elect directors, the number of directors shall be fixed from time to time exclusively by the Board of Directors pursuant to a resolution adopted by a majority of the total number of directors which the Corporation would have if there were no vacancies.


b)

Directors need not be stockholders to be qualified for election or service as a director of the Corporation.


Section 2.2.

Removal; Resignation.


Any director or the entire Board of Directors may be removed, with or without cause, by the holders of a majority of the shares then entitled to vote at an election of directors.  Any director may resign at any time upon notice given in writing to the Corporation.  A resignation is effective when the resignation is delivered unless the resignation specifies a later effective date or an effective date determined upon the happening of an event or events.  A resignation that is conditioned upon the director failing to receive a specified vote for reelection as a director may provide that it is irrevocable.


Section 2.3.

Newly Created Directorships and Vacancies.


Except as otherwise required by law and subject to the rights of the holders of any series of preferred stock with respect to such series of preferred stock, newly created directorships resulting from any increase in the authorized number of directors or any vacancies on the Board of Directors resulting from death, resignation, retirement, disqualification, removal from office or other cause may be filled by a majority vote of the directors then in office, though less than a quorum, or by a sole remaining director, or by the stockholders.  Directors so chosen shall hold office for a term expiring at the annual meeting of stockholders at which the term of office of the class to which they have been elected expires and until the director’s successor shall have been duly elected and qualified.  No decrease in the number of authorized directors constituting the entire Board of Directors shall shorten the term of any incumbent director.


Section 2.4.

Regular Meetings.


Regular meetings of the Board of Directors shall be held at the place, on the date and at the time as shall have been established by the Board of Directors and publicized among all directors.  A notice of a regular meeting the date of which has been so publicized shall not be required.


Section 2.5.

Special Meetings.


Special meetings of the Board of Directors may be called by the Chairman, the Chief Executive Officer, the President, or by two or more directors then in office and shall be held at the place, on the date, and at the time as they or he or she shall fix.  Notice of the place, date, and time of each special meeting shall be given each director either (a) by mailing written notice not less than five (5) days before the meeting, or (b) by telephone or by telegraphing or telexing or by facsimile or electronic transmission of the same not less than 24 hours before the meeting.  Unless otherwise stated in the notice thereof, any and all business may be transacted at a special meeting.


Section 2.6.

Quorum.


At any meeting of the Board of Directors, a majority of the total number of the whole Board of Directors shall constitute a quorum for all purposes.  If a quorum shall fail to attend any meeting, a majority of those present may adjourn the meeting to another place, date or time, without further notice or waiver thereof.


Section 2.7.

Participation in Meetings by Conference Telephone or Other Communications Equipment.


Members of the Board of Directors, or of any committee thereof, may participate in a meeting of the Board or committee by means of conference telephone or other communications equipment by means of which all persons participating in the meeting can hear each other and such participation shall constitute presence in person at the meeting.



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Section 2.8.

Conduct of Business.


At any meeting of the Board of Directors, business shall be transacted in the order and manner as the Board may from time to time determine, and all matters shall be determined by the vote of a majority of the directors present, except as otherwise provided in these bylaws or required by law.  If the Corporation has an even number of directors in office, all of whom are in attendance at the meeting, who are equally divided, the Chairman of the Board shall have the deciding vote.  The Board of Directors may take action without a meeting if all members thereof consent thereto in writing or by electronic transmission, and the writing or writings or transmission or transmissions are filed with the minutes of proceedings of the Board of Directors.  Such filing shall be in paper form if the minutes are maintained in paper form and shall be in electronic form if the minutes are maintained in electronic form.


Section 2.9.

Compensation of Directors.


Unless otherwise restricted by the Certificate of Incorporation, the Board of Directors shall have the authority to fix the compensation of the directors.  The directors may be paid their expenses, if any, of attendance at each meeting of the Board of Directors and may be paid a fixed sum for attendance at each meeting of the Board of Directors or paid a stated salary or paid other compensation as directors.  No such payment shall preclude any director from serving the Corporation in any other capacity and receiving compensation therefor.  Members of standing or special committees may be allowed compensation for attending committee meetings.


ARTICLE III

Committees


Section 3.1.

Committees of the Board of Directors.


The Board of Directors may from time to time designate standing and special committees of the Board, with such lawfully delegable powers and duties as it thereby confers, to serve at the pleasure of the Board and shall, for those committees and any others provided for herein, elect a director or directors to serve as the member or members, designating, if it desires, other directors as alternate members who may replace any absent or disqualified member at any meeting of the committee.  In the absence or disqualification of any member of any committee and any alternate member in his or her place, the member or members of the committee present at the meeting and not disqualified from voting, whether or not he or she or they constitute a quorum, may by unanimous vote appoint another member of the Board of Directors to act at the meeting in the place of the absent or disqualified member.  The responsibilities of each standing committee shall be stated in the committee’s charter, as approved by the Board of Directors.  Each special committee shall perform such duties and exercise such powers as may be delegated to it expressly by the Board of Directors.


Section 3.2.

Conduct of Business.


Each committee may determine the procedural rules for meeting and conducting its business and shall act in accordance therewith, except as otherwise provided herein or required by law.


ARTICLE IV

Officers


Section 4.1.

Generally.


The officers of the Corporation shall consist of a Chairman of the Board, a Chief Executive Officer or a President, a Secretary, and a Treasurer.  The officers of the Corporation may consist of a Chief Financial Officer, one or more Vice Presidents, a Controller, and the other officers as may from time to time be appointed by the Board of Directors.  Officers shall be elected by the Board of Directors, which shall consider that subject at its first meeting after every annual meeting of stockholders.  Each officer shall hold office until his or her successor is elected and qualified or until his or her earlier resignation or removal.  Any number of offices may be held by the same person.  The salaries of officers elected by the Board of Directors shall be fixed from time to time by the Board of Directors or by the officers as may be designated by resolution of the Board.


Section 4.2.

Chairman of the Board.


The Chairman of the Board shall preside at all meetings of stockholders and the Board of Directors.  The Chairman shall have the other powers and duties as may be delegated from time to time by the Board of Directors.



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Section 4.3.

Chief Executive Officer.


The Chief Executive Officer shall, subject to the oversight of the Board of Directors, have general supervision, direction and control of the business and the officers, employees and agents of the Corporation.  In the absence of the Chairman of the Board of Directors, the Chief Executive Officer, if such officer is a director, shall preside at all meetings of the Board of Directors, unless the Board of Directors determines otherwise.  The Chief Executive Officer shall perform such other duties and have such other powers as the Board of Directors shall designate from time to time.


Section 4.4.

President.


Subject to the oversight of the Board of Directors and the supervision, control and authority of the Chief Executive Officer, the President shall have general supervision, direction and control of the business and the officers, employees and agents of the Corporation.  In the absence of a Chief Executive Officer appointed by the Board, the President shall be the chief executive officer of the Corporation.  The President shall perform such other duties and have such other powers as the Board of Directors shall designate from time to time.


Section 4.5.

Vice President.


Each Vice President shall have the powers and duties as may be delegated to him or her by the Board of Directors.  One (1) Vice President may be designated by the Board to perform the duties and exercise the powers of the chief executive officer in the event of that officer’s absence or disability.


Section 4.6.

Chief Financial Officer and Treasurer.


Each of the Chief Financial Officer and the Treasurer shall control, monitor and arrange the financial affairs of the corporation and shall maintain the financial records of the Corporation, consistent with the responsibilities delegated to each of them by the Corporation’s Chief Executive Officer or President.  The Chief Financial Officer or Treasurer, as the case may be, shall receive and deposit all monies belonging to the Corporation and shall pay out the same only in such manner as the Board of Directors may from time to time determine, and shall have such other powers and perform such other duties as the Board of Directors may require.


Section 4.7.

Secretary.


The Secretary shall issue all authorized notices for, and shall keep minutes of, all meetings of the stockholders and the Board of Directors.  He or she shall have charge of the corporate books and shall perform the other duties as the Board of Directors may from time to time prescribe.


Section 4.8.

Controller.


The Controller shall have charge of the accounting affairs of the Corporation and shall have such other powers and perform such other duties as the Board of Directors shall designate.  The Controller shall report to the Chief Financial Officer.


Section 4.9.

Delegation of Authority.


The Board of Directors may from time to time delegate the powers or duties of any officer to any other officers or agents, notwithstanding any provision hereof.


Section 4.10.

Removal.


The Board of Directors may remove any officer of the Corporation at any time, with or without cause.


Section 4.11.

Action with Respect to Securities of Other Corporations.


Unless otherwise directed by the Board of Directors, the Chief Executive Officer or any officer of the Corporation authorized by the Chief Executive Officer shall have power to vote and otherwise act on behalf of the Corporation, in person or by proxy, at any meeting of stockholders or equity holders of any other corporation or entity or in which this Corporation may hold securities and otherwise to exercise any and all rights and powers which this Corporation may possess by reason of its ownership of securities in the other corporation or entity.



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ARTICLE V

Stock


Section 5.1.

Certificates of Stock.


Each stockholder shall be entitled to a certificate signed by, or in the name of the Corporation by, the Chairman of the Board, the Vice Chairman of the Board, the Chief Executive Officer, President or Vice President, and by the Secretary or an Assistant Secretary, or the Treasurer or an Assistant Treasurer, certifying the number of shares owned by him or her unless the Board of Directors provides by resolution that some or all of any or all classes or series of stock shall be uncertificated shares.  Any or all of the signatures on the certificate may be by facsimile.


Section 5.2.

Transfers of Stock.


Transfers of stock shall be made only upon the transfer books of the Corporation kept at an office of the Corporation or by transfer agents designated to transfer shares of the stock of the Corporation.  Except where a certificate is issued in accordance with Section 5.3 of these bylaws, an outstanding certificate for the number of shares involved shall be surrendered for cancellation before a new certificate is issued therefore.


Section 5.3.

Lost, Stolen or Destroyed Certificates.


In the event of the loss, theft, or destruction of any certificate of stock, another may be issued in its place pursuant to the regulations that the Board of Directors may establish concerning proof of the loss, theft, or destruction and concerning the giving of a satisfactory bond or bonds of indemnity.


Section 5.4.

Regulations.


The issue, transfer, conversion and registration of certificates of stock shall be governed by the other regulations as the Board of Directors may establish.


Section 5.5.

Record Date.


a)

In order that the Corporation may determine the stockholders entitled to notice of or to vote at any meeting of stockholders, or to receive payment of any dividend or other distribution or allotment of any rights or to exercise any rights in respect of any change, conversion or exchange of stock or for the purpose of any other lawful action, the Board of Directors may, except as otherwise required by law, fix a record date, which record date shall not precede the date on which the resolution fixing the record date is adopted and which record date shall not be more than 60 nor less than 10 days before the date of any meeting of stockholders, nor more than 60 days prior to the time for the other action described above; provided , however , that if no record date is fixed by the Board of Directors, the record date for determining stockholders entitled to notice of or to vote at a meeting of stockholders shall be at the close of business on the day next preceding the day on which notice is given or, if notice is waived, at the close of business on the day next preceding the day on which the meeting is held, and, for determining stockholders entitled to receive payment of any dividend or other distribution or allotment of rights or to exercise any rights of change, conversion or exchange of stock or for any other purpose, the record date shall be at the close of business on the day on which the Board of Directors adopts a resolution relating thereto.


b)

A determination of stockholders of record entitled to notice of or to vote at a meeting of stockholders shall apply to any adjournment of the meeting; provided , however , that the Board of Directors may fix a new record date for the adjourned meeting.




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c)

In order that the Corporation may determine the stockholders entitled to consent to corporate action in writing without a meeting, the Board of Directors may fix a record date, which date shall not precede the date upon which the resolution fixing the record date is adopted by the Board of Directors, and which date shall not be more than 10 days after the date upon which the resolution fixing the record date is adopted by the Board of Directors.  Any stockholder of record seeking to have the stockholders authorize or take corporate action by written consent shall, by written notice to the Secretary, request the Board of Directors to fix a record date.  The Board of Directors shall promptly, but in all events within 10 days after the date on which such a request is received, adopt a resolution fixing the record date (unless the Board of Directors has previously fixed a record date pursuant to the first sentence hereof).  If no record date has been fixed by the Board of Directors pursuant to the first sentence hereof or otherwise within 10 days of the date on which such a request is received, the record date for determining stockholders entitled to consent to corporate action in writing without a meeting, where no prior action by the Board of Directors is required by applicable law, shall be the first date on which a signed written consent setting forth the action taken or proposed to be taken is delivered to the Corporation by delivery to its registered agent in Delaware, its principal place of business, or to any officer or agent of the Corporation having custody of the book in which proceedings of meetings of stockholders are reported.  Delivery shall be by hand or by certified or registered mail, return receipt requested.  If no record date has been fixed by the Board of Directors and prior action by the Board of Directors is required by applicable law, the record date for determining stockholders entitled to consent to corporate action in writing without a meeting shall be at the close of business on the date on which the Board of Directors adopts the resolution taking the prior action.


ARTICLE VI

Notices


Section 6.1.

Notices.


If mailed, notice to stockholder shall be deemed given when deposited in the mail, postage prepaid, directed to the stockholder at such stockholder’s address as it appears on the records of the Corporation.  Without limiting the manner by which notice otherwise may be given effectively to stockholders, any notice to stockholders may be given by electronic transmission in the manner provided in Section 232 of the Delaware General Corporation Law.


Section 6.2.

Waivers.


A written waiver of any notice, signed by a stockholder or director, or a waiver by electronic transmission by such person, whether given before or after the time of the event for which notice is to be given, shall be deemed equivalent to the notice required to be given to such person.  Neither the business nor the purpose of any meeting need be specified in the waiver.  Attendance at any meeting shall constitute waiver of notice except attendance for the sole purpose of objecting at the beginning of the meeting to the transaction of any business because the meeting is not lawfully called or convened.


ARTICLE VII

Miscellaneous


Section 7.1.

Corporate Seal.


The Board of Directors may provide a suitable seal, containing the name of the Corporation, which seal shall be in the charge of the Secretary.  If and when so directed by the Board of Directors, duplicates of the seal may be kept and used by the Treasurer or by an Assistant Secretary or Assistant Treasurer.


Section 7.2.

Facsimile Signatures.


In addition to the provisions for use of facsimile signatures elsewhere specifically authorized in these Bylaws, facsimile signatures of any officer or officers of the Corporation may be used whenever and as authorized by the Board of Directors or a committee thereof.


Section 7.3.

Reliance upon Books, Reports and Records.


Each director, each member of any committee designated by the Board of Directors, of the Corporation shall, in the performance of his or her duties, be fully protected in relying in good faith upon the books of account or other records of the Corporation and upon such information, opinions, reports or statements presented to the Corporation by any of its officers or employees, or committees of the Board of Directors so designated, or by any other person as to matters which such director or committee member reasonably believes are within such other person’s professional or expert competence and who has been selected with reasonable care by or on behalf of the Corporation.



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Section 7.4.

Fiscal Year.


The fiscal year of the Corporation shall be as fixed by the Board of Directors.


Section 7.5.

Time Periods.


In applying any provision of these bylaws which requires that an act be done or not be done a specified number of days prior to an event or that an act be done during a period of a specified number of days prior to an event, calendar days shall be used, the day of the doing of the act shall be excluded, and the day of the event shall be included.


Section 7.6

Electronic Transmission.


When used in these Bylaws, the terms “written” and “in writing” shall include any “electronic transmission,” as defined in Section 232(c) of the Delaware General Corporation Law, including without limitation any telegram, cablegram, facsimile transmission and communication by electronic mail.


ARTICLE VIII

Indemnification


Section 8.1.

Right to Indemnification.


Each person who was or is made a party or is threatened to be made a party to or is otherwise involved in any action, suit or proceeding, whether civil, criminal, administrative or investigative (a “proceeding”), by reason of the fact that he or she is or was a director or an officer of the Corporation or is or was serving at the request of the Corporation as a director, officer, employee or agent of another corporation or of a partnership, joint venture, trust or other enterprise, including service with respect to an employee benefit plan (an “indemnitee”), whether the basis of the proceeding is alleged action in an official capacity as a director or officer or in any other capacity while serving as a director, officer, employee or agent, shall be indemnified and held harmless by the Corporation to the fullest extent permitted by applicable law as the same exists or may hereafter be amended (but, in the case of any such amendment, only to the extent that the amendment permits the Corporation to provide broader indemnification rights than such law permitted the Corporation to provide prior to such amendment), against all expense, liability and loss (including attorneys’ fees, judgments, fines, ERISA excise taxes or penalties and amounts paid in settlement) reasonably incurred or suffered by the indemnitee in connection therewith; provided, however, that, except as provided in Section 8.3 with respect to proceedings to enforce rights to indemnification and advancement of expenses, the Corporation shall indemnify any such indemnitee in connection with a proceeding (or part thereof) initiated by the indemnitee only if the proceeding (or part thereof) was authorized by the Board of Directors of the Corporation.


Section 8.2.

Right to Advancement of Expenses.


The right to indemnification conferred in Section 8.1 shall include the right to be paid by the Corporation the expenses (including attorney’s fees) incurred in defending any such proceeding in advance of its final disposition (an “advancement of expenses”); provided, however, that, if the Delaware General Corporation Law requires, an advancement of expenses incurred by an indemnitee in his or her capacity as a director or officer (and not in any other capacity in which service was or is rendered by the indemnitee, including, without limitation, service to an employee benefit plan) shall be made only upon delivery to the Corporation of an undertaking (an “undertaking”), by or on behalf of the indemnitee, to repay all amounts so advanced if it shall ultimately be determined by final judicial decision from which there is no further right to appeal (a “final adjudication”) that the indemnitee is not entitled to be indemnified for the expenses under this Section 8.2 or otherwise.  The rights to indemnification and to the advancement of expenses conferred in Sections 8.1 and 8.2 shall be contract rights and such rights shall continue as to an indemnitee who has ceased to be a director, officer, employee or agent and shall inure to the benefit of the indemnitee’s heirs, executors and administrators.




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Section 8.3.

Right of Indemnitee to Bring Suit.


If a claim under Section 8.1 or 8.2 is not paid in full by the Corporation within 60 days after a written claim has been received by the Corporation, except in the case of a claim for an advancement of expenses, in which case the applicable period shall be 20 days, the indemnitee may at any time thereafter bring suit against the Corporation to recover the unpaid amount of the claim to the fullest extent permitted by law.  If successful in whole or in part in any such suit, or in a suit brought by the Corporation to recover an advancement of expenses pursuant to the terms of an undertaking, the indemnitee shall be entitled to be paid also the expense of prosecuting or defending such suit.  In any suit brought by (i) the indemnitee to enforce a right to indemnification hereunder (but not in a suit brought by the indemnitee to enforce a right to an advancement of expenses) it shall be a defense that, and (ii) the Corporation to recover an advancement of expenses pursuant to the terms of an undertaking, the Corporation shall be entitled to recover such expenses upon a final adjudication that, the indemnitee has not met any applicable standard for indemnification set forth in the Delaware General Corporation Law.  Neither the failure of the Corporation (including its Board of Directors, independent legal counsel, or its stockholders) to have made a determination prior to the commencement of such suit that indemnification of the indemnitee is proper in the circumstances because the indemnitee has met the applicable standard of conduct set forth in the Delaware General Corporation Law, nor an actual determination by the Corporation (including its Board of Directors, independent legal counsel, or its stockholders) that the indemnitee has not met the applicable standard of conduct, shall create a presumption that the indemnitee has not met the applicable standard of conduct or, in the case of such a suit brought by the indemnitee, be a defense to the suit.  In any suit brought by the indemnitee to enforce a right to indemnification or to an advancement of expenses hereunder, or brought by the Corporation to recover an advancement of expenses pursuant to the terms of an undertaking, the burden of proving that the indemnitee is not entitled to be indemnified, or to such advancement of expenses, under this Section 8 or otherwise shall be on the Corporation.


Section 8.4.

Non-exclusivity of Rights.


The rights to indemnification and to the advancement of expenses conferred in this Article VIII shall not be exclusive of any other right which any person may have or hereafter acquire under any statute, the Corporation’s Certificate of Incorporation, bylaws, agreement, vote of stockholders or disinterested directors or otherwise.


Section 8.5.

Insurance.


The Corporation may maintain insurance, at its expense, to protect itself and any director, officer, employee or agent of the Corporation or another corporation, partnership, joint venture, trust or other enterprise against any expense, liability or loss, whether or not the Corporation would have the power to indemnify the person against the expense, liability or loss under the Delaware General Corporation Law.


Section 8.6.

Indemnification of Officers, Employees and Agents of the Corporation.


The Corporation may, to the extent authorized from time to time by the Board of Directors, grant rights to indemnification and to the advancement of expenses to any officer, employee or agent of the Corporation to the fullest extent of the provisions of this Article VIII with respect to the indemnification and advancement of expenses of directors and officers of the Corporation.


ARTICLE IX

Forum for Adjudication of Disputes


Unless the Corporation consents in writing to the selection of an alternative forum, the sole and exclusive forum for (i) any derivative action or proceeding brought on behalf of the Corporation, (ii) any action asserting a claim of breach of a fiduciary duty owed by any director, officer or other employee of the Corporation to the Corporation or the Corporation’s stockholders, (iii) any action asserting a claim arising pursuant to any provision of the Delaware General Corporation Law, or (iv) any action asserting a claim governed by the internal affairs doctrine shall be a state or federal court located within the state of Delaware, in all cases subject to the court’s having personal jurisdiction over the indispensible parties named as defendants. Any person or entity purchasing or otherwise acquiring any interest in shares of capital stock of the Corporation shall be deemed to have notice of and consented to the provisions of this Article IX.


ARTICLE X

Amendments


These Bylaws may be altered, amended and repealed, and new bylaws adopted, only in compliance with and as authorized by the Certificate of Incorporation.



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ARTICLE XI

Force and Effect


These Bylaws are subject to the provisions of the Delaware General Corporation Law and the Certificate of Incorporation, as the same may be amended from time to time.  If any provision in these Bylaws is inconsistent with an express provision of either the Delaware General Corporation Law or the Certificate of Incorporation, the provisions of the Delaware General Corporation Law or the Certificate of Incorporation, as the case may be, shall govern, prevail, and control the extent of such inconsistency.



Adopted February 15, 2012


Amended May 6, 2013



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Exhibit 99.1


OPHTHALIX INC.


INSIDER TRADING POLICY

(As Adopted May 6, 2013)


THE NEED FOR A POLICY STATEMENT


The purchase and sale of securities while possessing material nonpublic (“inside”) information relating to the issuer of such securities is prohibited by Federal securities laws.  In addition, such laws prohibit the selective disclosure of such information to others who may trade.  In the course of performing their duties, many directors, officers and employees of OphthaliX Inc., a Delaware corporation, or one of its consolidated subsidiaries (the “ Company ”) may have access to material nonpublic information about the Company or about the Company’s business (including information about other companies with which the Company does or may do business).


The Company has adopted this Policy Statement to avoid even the appearance of improper conduct on the part of any the Company management and employees.  This Policy Statement is designed to protect and enhance the reputation of the Company and its management and employees for integrity, ethical conduct, and good corporate citizenship.


STATEMENT OF POLICY


No director, officer, or employee or other affiliate of the Company (including directors, officers and employees of any consolidated subsidiary of the Company) who has material nonpublic information relating to the Company may buy or sell securities of the Company, directly or indirectly, or engage in any other action to take personal advantage of that information, or to pass it on to others.  This policy also applies to information relating to any other company, including customers or suppliers, obtained in the course of employment or management discussions.  This policy shall not apply to sales made in compliance with Rule 10b5-1 as set forth below.


No one covered by this Policy Statement may pass material nonpublic information on to others or recommend to anyone the purchase or sale of any securities when he or she is aware of such information.


Transactions that may be necessary or justifiable for independent reasons (such as the need to raise money for an emergency expenditure) are no exception.  Even the appearance of an improper transaction must be avoided to preserve the Company’s reputation for adhering to the highest standards of conduct.


PROCEDURES


Blackout Periods .  Investment by the Company officers, directors, and employees in the Company securities is encouraged.  In order to protect both the Company and its individual officers, directors and employees and others from liability that could result from a violation of the legal requirements described below, no person covered by this Policy Statement is permitted to trade in the Company’s securities during quarterly blackout periods beginning 15 days before the end of a quarter and ending after the second full business day following the release of the Company’s earnings for that quarter and during certain event-specific blackouts.  


These blackout periods shall not apply to transactions which comply with Rule 10b5-1 promulgated by the Securities and Exchange Commission (the “ SEC ”), provided that the selling shareholder furnishes a copy of the written plan with the broker proposing to sell securities under Rule 10b5-1 and provides a copy to the Company.  


Preclearance of Trades .  To provide assistance in preventing inadvertent violations and avoiding even the appearance of an improper transaction (which could result, for example, when an executive officer engages in a trade while unaware of a pending major development), the procedure set forth below must be followed by all directors, officers, and employees.


All transactions in the Company securities (acquisitions, dispositions, transfers, etc.) by any member of the above mentioned groups must be pre-cleared by the Company’s legal counsel and the Corporate Secretary .  In addition, each insider should pre-clear transactions in the Company securities by the following persons because transactions by them may be attributed to such insider:


·

any member of the insider’s household;

·

any trust or estate in which the insider or a household member is a settlor, beneficiary, trustee, executor or the like;

·

any partnership in which the insider or a household member is a general partner;

·

any corporation in which such insider or any household members either singly or together own a controlling interest; or

·

any trust, corporation, charitable organization or other firm, entity or group where the insider or a household member has or shares with others the power to decide whether to buy or sell the Company securities.





If an individual contemplates a transaction in the Company securities, he or she must contact the Company’s legal counsel or the Corporate Secretary in advance.  This pre-clearance requirement does not apply to stock option exercises.


Reporting of Disclosures .  If any person has any doubt as to whether information in his or her possession is material and nonpublic, such person shall not disclose that information without first discussing the same with the Company’s legal counsel .  If material nonpublic information is inadvertently disclosed, no matter what the circumstances, by any director, executive officer or employee, the person making or discovering that disclosure should immediately report the facts to the Company’s legal counsel .  Likewise, any potential insider trading violation or discovery of such potential violation should be immediately reported to the Company’s legal counsel.


EXPLANATION OF THE LAW


The Law and Appearances .  Rule 10b-5 under the Exchange Act makes it unlawful to buy or sell the Company securities or the securities of other companies with which the Company has dealings based upon material nonpublic information, or to pass such information along to another who engages in such trades (i.e., tipping).  Moreover, it is unlawful for any employee to attempt to take any economic or other personal advantage of such information.  This means that each executive officer, director and employee who has material nonpublic information (each, an “insider”) must not permit any member of his or her immediate family or anyone acting on his or her behalf, or anyone to whom he or she has disclosed the information, to purchase or sell securities.  Remember, anyone who has material inside information is an insider; it is not limited to corporate executives.


If in fact investors do buy or sell on the basis of nonpublic information obtained directly or indirectly from insiders, such market activity may be used, correctly or incorrectly, as evidence that the information was material.  Moreover, a person in possession of inside information who trades in securities will probably be deemed to have traded “based on” such information even though the inside information was not a significant or determining factor in his or her decision to buy or sell the securities.


Remember, if a person’s transactions in the Company securities become the subject of scrutiny, they will be viewed after-the-fact with the benefit of hindsight.  As a result, before engaging in any transaction each person should carefully consider how regulators and others might view his or her transactions in hindsight.


Material Information .  Information is “material” when there is a substantial likelihood that a reasonable investor would consider the information important in deciding whether to buy, hold or sell securities.  In short, any information which could reasonably affect the price of securities is material.


Some examples of information that may be material depending on the circumstances are:


·

earnings forecast or changes therein;

·

significant new product or discovery;

·

significant merger, acquisition, divestiture or joint venture;

·

declaration or omission of dividends or change in dividend policy;

·

stock split or stock dividend;

·

significant change in capital investment plans;

·

purchase or sale of a significant asset;

·

change in control or a significant change in management;

·

acquisition or loss of a significant contract;

·

significant change in product pricing or physical volume;

·

significant expansion or curtailment of operations or layoffs;

·

significant increase or decline in orders;

·

significant litigation or government investigation;

·

significant labor dispute;

·

significant dispute with major suppliers, customers or subcontractors;

·

significant write-off or loss;

·

significant change in prior reported earnings;

·

significant shortage of materials or supplies;

·

significant cost overrun on major construction;

·

borrowing of significant amount of funds;

·

sale of a significant amount of additional securities;

·

establishment of a stock repurchase program;

·

tender offer for another company’s securities; and

·

significant liquidity problems.



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Non-Public Information .  Information is “nonpublic” when it has not yet been disclosed generally to the marketplace.  In determining whether information is nonpublic, please note that:


(1)

Information received during the course of employment about another company in circumstances indicating that it has not yet in general circulation should be considered nonpublic;


(2)

All information that officers, directors, employees or others learn about the Company or its business plans in connection with their office or employment is potentially “inside” information until publicly disclosed or made available by the Company; and


(3)

All such information should be treated as confidential and proprietary to the Company.


If this nonpublic information is also “material”, those possessing such information are required by law and the Company policy to refrain from trading and from passing the information on to others who may trade.  Information is considered to be public only when it has been released to the public through appropriate channels and enough time has elapsed to permit the investment market to adsorb and evaluate the information.


Securities Covered .  The “securities” covered by Rule 10b-5 include not only the Company’s common stock and debt securities, but also derivative securities such as options, stock appreciation rights, puts and calls and any other security that relates to, or derives its value by reference to, the Company’s common stock.  Therefore, each individual should take care to avoid any actions which may result in indirect purchases of the Company stock during periods of time such individual is in possession of material inside information.


Tipping Information to Others .  Whether the information in an individual’s possession is proprietary information of the Company or is information that could have an impact on the price of the Company securities, such individual must not pass the information on to others who do not have a legitimate business reason to know such information, including family members and others living in such individual’s household or friends and casual acquaintances.  Confidential material information should be disclosed only to key personnel and principal outside advisors whose work for the Company requires that they have such information.  All persons given access to such information should be advised of their insider status and told not to disclose the information further except as absolutely necessary for corporate purposes.


Penalties and Enforcement .  If there are purchases or sales of the Company securities by persons possessing material inside information, such transactions, pursuant to U.S. Federal securities laws, may give rise to private lawsuits for damages or to civil and criminal proceedings by the SEC.


These Federal securities laws provide for significant monetary and criminal penalties.  In addition, civil penalties can be imposed which, for the person who committed the violation, can be significant.  The SEC has also been given substantial enforcement powers, including the authority to obtain civil injunctions, impose penalties, and bar violators from serving as directors or officers of public companies.  In a situation where an insider discloses material nonpublic information to another and the tippee engages in insider trading, these penalties may be applied to the insider disclosing such information regardless of whether such insider derived any benefit from the tippee’s actions.


In addition, violation of the Company’s policy could subject the insider to serious disciplinary actions, including termination of employment or removal from office.


Needless to say, any of the above consequences, even an SEC investigation that does not result in prosecution, can tarnish one’s reputation and irreparably damage a career.


Liability of Supervisory Persons .  Under the Federal securities laws, courts will likely focus not only on persons who engage in unlawful insider trading, but on persons who fail to take steps to prevent those violations.  The Company, as well as a director, executive officer or other the Company manager, is subject to liability under Federal securities laws if the Company or such person knew or recklessly disregarded the fact that a person directly or indirectly under the Company’s or such person’s control was likely to engage in insider trading and failed to take appropriate steps to prevent such an act before it occurred.  In addition, disclosure of material nonpublic information to others may put the insider at risk if the tippee engages in illegal trading.




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RULE 144


A part of any insider trading policy is an understanding of Rule 144 promulgated by the SEC to determine whether a person would be a statutory underwriter at the time of any sale into the market pursuant to the exemption under Section 4(1) of the Securities Act.  Rule 144 applies both to restricted securities (shares received by the selling shareholder from the issuer or an affiliate of the issuer without registration) and to control shares (those shares which may be otherwise free-trading but are held by an affiliate of the issuer).


Restricted shares held by an affiliate of the issuer can only be resold into the public trading market if (i) the shareholder has owned the shares for at least six months; (ii) the issuer is current in filing its periodic reports with the SEC; (iii) sales during any three-month period are less than 1% of the issuer’s total outstanding shares; (iv) the shares are sold in broker transactions (where the broker does nothing more than execute the order, receives no more than the usual commission, and does not solicit orders to buy the shares) or directly with a market maker; and (v) the seller files a Form 144 with the SEC (except for sales during any three-month period of fewer than 5,000 shares and proceeds of less than $50,000).


Free-trading shares held by an affiliate of the issuer are not subject to any holding period, but must meet all other provisions of Rule 144 to the same extent as an affiliate selling restricted shares.  Any otherwise free-trading shares held by an affiliate of the Company should be marked with a control legend by the transfer agent and designated on the transfer records as an affiliate.  The Company should notify the transfer agent of each person deemed an affiliate of the Company and update this list on a regular basis.


ADDITIONAL ASSISTANCE


Any person who has any questions about specific transactions may obtain additional guidance from the Company’s legal counsel.  Remember, however, the ultimate responsibility for adhering to this Policy Statement and avoiding improper transactions rests with each director, officer and employee possessing material nonpublic information.  It is imperative that each person use his or her best judgment.


This Insider Trading Policy is hereby adopted by the unanimous written consent of the Board of Directors which may be executed in one or more counterparts, each of which shall be regarded as an original and all of which shall constitute one and the same instrument, but which shall be effective as of the date of the last signature hereto.




4


Exhibit 99.2


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Third Party Presented New Data at the ARVO 2013 Annual Meeting in Seattle, WA, Validating the use of A3 Adenosine Receptor Agonists for Lowering Intra Ocular Pressure and for the Treatment of Glaucoma


Petach Tikva, Israel, May 10, 2013 / OphthaliX, Inc. (OTC BB: OPLI) , announced today that it has come to its knowledge that Professor M. Francesca Cordeiro, a Professor of Glaucoma & Retinal Neurodegeneration Studies from UCL and Imperial College in London, presented new data generated independently and unrelated to OphthaliX, validating the utilization of the A3 adenosine receptor (A3AR) agonists for lowering intra ocular pressure (IOP) and for the treatment of Glaucoma, during the ARVO 2013 Annual Meeting in Seattle, Washington, which took place from May 5 th - 9 th 2013. OphthaliX platform technology is based on targeting the A3AR and as such this independent and unrelated data provides an additional validation for the scientific and medical approach of OphthaliX.


Dr. Cordeiro and her group presented data showing that an A3 adenosine receptor agonist markedly reduced the intra ocular pressure (IOP) in 2 pre-clinical models of Glaucoma including partial optic nerve transection (pONT) and ocular hypertension model (OHT). It was also found that A3AR activation is neuroprotective against retinal ganglion cell apoptosis in these experimental models. Dr. Cordeiro concluded that targeting A3AR and delineation of its relationship with retinal ganglion cell apoptosis could have great potential in the management of retinal neurodegeneration, such as glaucoma.

It is well established that neuroprotection, the ability to forestall and reverse degeneration of brain and eye nerves, is a highly sought-after medical object of research which will enable physicians not only to stop degenerations in a disease like glaucoma, but actually to reverse them.


“The validation for the use of A3AR agonists for the treatment of Glaucoma, including the potential neuroprotective effect, by leading eye scientists at ARVO, a prestigious and respected eye research scientific conference is very exciting,” commented Dr. Michael Belkin, Professor of ophthalmology and the director of the Chief ophthalmic technologies laboratory at Tel Aviv University in the Sheba Medical Center. “OphthaliX technology is targeting the A3AR and this type of validation indicates OphthaliX potential to be the first neuroprotective compound to be clinically effective. “


About OphthaliX Inc.


OphthaliX Inc. is a clinical-stage biopharmaceutical company focused on developing therapeutic products for the treatment of ophthalmic disorders. OphthaliX's product candidate, CF101, is being developed to treat three ophthalmic indications: dry eye syndrome; glaucoma and uveitis.


About CF101


CF101, an A3 adenosine receptor agonist, is a novel, first in class, small molecule, orally bioavailable drug which demonstrated efficacy and an excellent safety profile in Phase 2 clinical studies. CF101 is currently developed for ophthalmic indications, including dry eye syndrome (Phase 3), glaucoma (Phase 2) and Uveitis. CF101 is also developed for the treatment of autoimmune inflammatory diseases including rheumatoid arthritis (Phase 2b) and psoriasis (Phase 2/3).


Contact:


KCSA Strategic Communications

Jeff Corbin / Phil Carlson

jcorbin@kcsa.com / pcarlson@kcsa.com

212-896-1233


This release contains forward-looking statements regarding OphthaliX’s future plans and expected performance based on assumptions the Company believes to be reasonable.  A number of risks and uncertainties could cause actual results to differ materially from these statements, including, without limitation, the success rate of business development efforts and the timeliness of development activities, and other risk factors described from time to time in the Company’s reports filed with the SEC.  In addition, the Company operates in an industry sector where securities values are highly volatile and may be influenced by economic and other factors beyond the Company’s control. OphthaliX undertakes no obligation to publicly update these forward-looking statements, whether as a result of new information, future events or otherwise.