Menlo Therapeutics Inc. (Form: DEFA14A, Received: 05/10/2019 16:14:58)

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Important Notice Regarding the Availability of Proxy Materials for the Shareholder Meeting of MENLO THERAPEUTICS INC. To Be Held On: June 25, 2019 at 200 Cardinal Way, 2nd Floor, Redwood City, California 94603 COMPANY NUMBER ACCOUNT NUMBER CONTROL NUMBER This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. We encourage you to access and review all of the important information contained in the proxy materials before voting. If you want to receive a paper or e-mail copy of the proxy materials you must request one. There is no charge to you for requesting a copy. To facilitate timely delivery please make the request as instructed below before 6/14/19. Please visit http://www.astproxyportal.com/ast/21994/, where the following materials are available for view: • Notice of Annual Meeting of Stockholders • Proxy Statement • Form of Electronic Proxy Card • Annual Report on Form 10-K TO REQUEST MATERIAL: TELEPHONE: 888-Proxy-NA (888-776-9962) 718-921-8562 (for international callers) E-MAIL: info@astfinancial.com WEBSITE: https://us.astfinancial.com/OnlineProxyVoting/ProxyVoting/RequestMaterials TO VOTE: ONLINE: To access your online proxy card, please visit www.voteproxy.com and follow the on-screen instructions or scan the QR code with your smartphone. You may enter your voting instructions at www.voteproxy.com up until 11:59 PM Eastern Time the day before the cut-off or meeting date. IN PERSON: You may vote your shares in person by attending the Annual Meeting. TELEPHONE: To vote by telephone, please visit www.voteproxy.com to view the materials and to obtain the toll free number to call. MAIL: You may request a card by following the instructions above. 1. Election of Directors: NOMINEES: 2. Ratification of appointment of Mayer Hoffman McCann LLP as independent registered public accounting firm for fiscal year 2019. Aaron Royston, M.D. Class I director Elisabeth Sandoval Class I director The undersigned hereby acknowledges receipt of the Notice of 2019 Annual Meeting of Shareholders, the Proxy Statement and the 2018 Annual Report to Shareholders furnished herewith. Please note that you cannot use this notice to vote by mail.