UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C.  20549

 

FORM 8-K

 

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

 

Date of report (Date of earliest event reported)    November 15, 2017

 

Wize Pharma, Inc.

(Exact Name of Registrant as Specified in its Charter)

 

Delaware   000-52545   88-0445167
(State or Other Jurisdiction
of Incorporation)
  (Commission File Number)   (IRS Employer
Identification No.)

 

5b Hanagar Street, Hod Hasharon, Israel   4527708
(Address of Principal Executive Offices)   (Zip Code)

 

Registrant’s telephone number, including area code:   +(972) 72-260-0536

 

OphthaliX, Inc., 10 Bareket Street, Petach Tikva, Israel 4951778

(Former Name or Former Address, if Changed Since Last Report)

  

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

  Written communications pursuant to Rule 425 under the Securities Act
     
  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
     
  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act
     
  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

 

Emerging growth company ☒

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☒

 

 

 

 

 

 

EXPLANATORY NOTE

 

As disclosed under the sections entitled “ The Merger ” and “ The Merger Agreement ” beginning at pages 59 and 73, respectively, of the final prospectus contained in the Registration Statement on Form S-4 and definitive proxy statement (the “Proxy Statement/Prospectus”) filed with the Securities and Exchange Commission (the “SEC”) on September 8, 2017 by OphthaliX, Inc., now known as Wize Pharma, Inc. (the “Company”), the Company entered into an Agreement and Plan of Merger (the “Merger Agreement”), dated as of May 21, 2017, with Bufiduck Ltd., a company formed under the laws of the State of Israel and a wholly owned subsidiary of the Company (“Merger Sub”) and Wize Pharma Ltd., a company formed under the laws of the State of Israel (“Wize Israel”), which contemplated the merger of Merger Sub with and into Wize Israel, with Wize Israel continuing as the surviving entity and becoming a wholly owned subsidiary of the Company.

 

This Current Report on Form 8-K (the “Report”) is being filed in connection with a series of transactions consummated by us that relate to the Merger (as defined below) between Merger Sub and Wize Israel, which transactions are described herein, together with certain related actions taken by the Company. This information is as of November 16, 2017, the date of the Merger (as defined below).

 

As a result of the Merger, the Company will continue the business operations of Wize Israel as a publicly traded company under the name “Wize Pharma, Inc.”

 

This Report contains summaries of the material terms of various agreements executed in connection with the Merger described herein. The summaries of these agreements are subject to, and are qualified in their entirety by reference to, these agreements, which are filed as exhibits hereto and incorporated herein by reference.

 

Prior to the Merger, the Company was a “shell company” as such term is defined in Rule 12b-2 under the Securities Exchange Act of 1934, as amended (“Exchange Act”). As a result of the Merger, the Company has ceased to be a “shell company.” The information contained in this Report constitutes the information necessary to satisfy the conditions contained in Rule 144(i)(2) under the Securities Act of 1933, as amended (“Securities Act”).

 

Unless derived from Wize Israel’s financial statements or otherwise indicated, U.S. dollar translations of NIS amounts presented in the Report are translated using the rate of NIS 3.529 to one U.S. dollar, the exchange rate reported by the Bank of Israel for September 30, 2017.

 

The information contained in this Report responds to the following items of Form 8-K:

       

Item 1.01 Entry into a Material Definitive Agreement.
Item 2.01 Completion of Acquisition or Disposition of Assets.
  Form 10 Information.
  Description of Business.
  Risk Factors.
  Management’s Discussion and Analysis of Financial Condition and Results of Operation.
  Properties.
  Security Ownership of Certain Beneficial Owners and Management.
  Directors and Executive Officers.
  Executive Compensation.
  Certain Relationships and Related Transactions, and Director Independence.
  Legal Proceedings.
  Market Price of and Dividends on the Registrant’s Common Equity and Related Stockholder Matters.
  Recent Sales of Unregistered Securities.
  Description of Registrant’s Securities to be Registered.
  Indemnification of Directors and Officers.
  Financial Statements and Supplementary Data.
  Changes in and Disagreements with Accountants on Accounting and Financial Disclosure.
  Financial Statements and Exhibits.
Item 2.03 Creation of Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registration
Item 3.02 Unregistered Sales of Equity Securities.
Item 3.03 Material Modification to Rights of Security Holders.
Item 4.01 Changes in Registrant’s Certifying Accountant.
Item 5.01 Changes in Control of Registrant.
Item 5.02 Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers.
Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.
Item 5.06 Change in Shell Company Status.
Item 7.01 Regulation FD.
Item 9.01 Financial Statements and Exhibits.

 

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SPECIAL NOTE REGARDING FORWARD LOOKING STATEMENTS

 

This Report contains forward-looking statements, about the Company’s expectations, beliefs or intentions regarding, among other things, its product development efforts, business, financial condition, results of operations, strategies or prospects. In addition, from time to time, the Company’s representatives have made or may make forward-looking statements, orally or in writing. Forward-looking statements can be identified by the use of forward-looking words such as “believe,” “expect,” “intend,” “plan,” “may,” “should” or “anticipate” or their negatives or other variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical or current matters. These forward-looking statements may be included in, but are not limited to, various filings made by us with the SEC, press releases or oral statements made by or with the approval of one of the Company’s authorized executive officers. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause the Company’s actual results to differ materially from any future results expressed or implied by the forward-looking statements. Many factors could cause the Company’s actual activities or results to differ materially from the activities and results anticipated in forward-looking statements, including, but not limited to, the factors summarized below.

 

This Report identifies important factors which could cause the Company’s actual results to differ materially from those indicated by the forward-looking statements, particularly those set forth under the heading “Risk Factors.” The risk factors included in this Report are not necessarily all of the important factors that could cause actual results to differ materially from those expressed in any of the Company’s forward-looking statements. Given these uncertainties, readers are cautioned not to place undue reliance on such forward-looking statements. Factors that could cause the Company’s actual results to differ materially from those expressed or implied in such forward-looking statements include, but are not limited to:

 

the Company has substantial debt which may adversely affect the Company by limiting future sources of financing, interfering with the Company’s ability to pay interest and principal on its indebtedness and subjecting the Company to additional risks;

 

the Company needs to raise additional capital to meet its business requirements in the future, and such capital raising may be costly or difficult to obtain and will dilute current shareholders’ ownership interests;

 

the Company’s current pipeline is based on a single compound, LO2A and on the continuation of the Company’s license to commercialize LO2A;

 

 ● the Company’s inability to expand its rights under the Company’s license agreement for LO2A may have a detrimental effect on its business;

 

the initiation, timing, progress and results of the Company’s preclinical studies, clinical trials and other product candidate development efforts;

 

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the Company’s ability to advance its product candidate into clinical trials or to successfully complete the Company’s preclinical studies or clinical trials;

 

the Company’s receipt of regulatory approvals for its product candidate, and the timing of other regulatory filings and approvals;

 

the clinical development, commercialization and market acceptance of LO2A;

 

  the Company’s ability to establish and maintain corporate collaborations;

 

the implementation of the Company’s business model and strategic plans for its business and product candidate;

 

the scope of protection the Company is able to establish and maintain for intellectual property rights covering LO2A and its ability to operate its business without infringing the intellectual property rights of others;

 

estimates of the Company’s expenses, future revenues, and capital requirements;

 

  competitive companies, technologies and its industry; and

 

statements as to the impact of the political and security situation in Israel on the Company’s business.

 

All forward-looking statements attributable to us or persons acting on the Company’s behalf speak only as of the date of this prospectus and are expressly qualified in their entirety by the cautionary statements included in this prospectus. The Company undertakes no obligations to update or revise forward-looking statements to reflect events or circumstances that arise after the date made or to reflect the occurrence of unanticipated events. In evaluating forward-looking statements, you should consider these risks and uncertainties.

 

Item 1.01 Entry into a Material Definitive Agreement.

 

The information contained in Item 2.01 below relating to the various agreements described therein is incorporated herein by reference.

 

Item 2.01 Completion of Acquisition of Disposition of Assets.

 

On November 16, 2017 (the “Closing Date”), the Company, which has been renamed “Wize Pharma, Inc.,” completed its transaction with Wize Israel in accordance with the terms of the Merger Agreement pursuant to which Merger Sub merged with and into Wize Israel, with Wize Israel surviving as a wholly owned subsidiary of the Company (the “Merger”).

 

In connection with the Merger and under the terms of the Merger Agreement:

 

at the effective time of the Merger (the “Effective Time”) each ordinary share of Wize Israel that was issued and outstanding was automatically cancelled and converted into 4.1445791236989 shares of common stock of the Company (the “Exchange Ratio”). As a result, an aggregate of 93,971,259 shares of common stock of the Company were issued to former Wize Israel shareholders. The pre-Merger stockholders of the Company retained an aggregate of 10,441,251 shares of the common stock of the Company;

 

a convertible loan entered into between Wize Israel and Rimon Gold Assets Ltd. (“Rimon Gold”) entered into on March 20, 2016 (as amended on March 30, 2016, the “2016 Loan Agreement”) in the principal amount of NIS 2 million (approximately $567,000) was adjusted based on the Exchange Ratio and became convertible into shares of Company common stock at a conversion price of NIS 0.15 (approximately $0.04), subject to adjustments for stock splits and similar events set forth in the 2016 Loan Agreement;

 

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a convertible loan entered into between Wize Israel and Ridge Valley Corporation (“Ridge”), and, by way of entering into assignments and assumption agreements following such date, also with Rimon Gold and Shimson Fisher (together, the “2017 Lenders”), entered into on January 15, 2017 (the “2017 Loan Agreement”) in the principal amount of NIS 3 million (approximately $850,000) was adjusted based on the Exchange Ratio and became convertible into shares of Company common stock at a conversion price of NIS 0.17 (approximately $0.05), subject to adjustments for stock splits and similar events set forth in the 2017 Loan Agreement;

 

under the 2016 Loan Agreement, as modified by the 2017 Loan Agreement, Rimon Gold has the right, until the lapse of 18 months following the conversion of the loan under the 2016 Loan Agreement, to invest up to NIS 3 million (approximately $850,000), in the aggregate, at an agreed price per share (as adjusted based on the Exchange Ratio) of NIS 0.21 (approximately $0.06), if the Company conducts any equity financing;

 

under the 2017 Loan Agreement, the 2017 Lenders, have the right until the lapse of 18 months following the conversion of the loan under the 2017 Loan Agreement, to make investments in the Company in an amount equal to NIS 1.50 for each NIS 1.00 of its respective loan amount converted, at an agreed price per share equal to 120% of the loan conversion price;

 

Wize Israel undertook to cause the Company to issue, to investors in a private placement of Wize Israel that was completed in July and August 2017, warrants to purchase (as adjusted based on the Exchange Ratio) an aggregate of 21,696,873 shares of common stock of the Company at an exercise price of $0.082 (the “PIPE Warrants”);

 

immediately prior to the Effective Time, the Company sold on an “as is” basis to Can-Fite BioPharma Ltd (“Can-Fite”) (the Company’s pre-Merger parent and pre-Merger holder of approximately 82% of the outstanding shares of common stock of the Company) all the ordinary shares of Eyefite Ltd., a former wholly owned subsidiary of the Company, in exchange for the irrevocable cancellation and waiver of all indebtedness owed by the Company and Eyefite to Can-Fite, including approximately $5 million of deferred payments owed by the Company and Eyefite to Can-Fite and, as part of the purchase of Eyefite, Can-Fite also assumed certain accrued milestone payments in the amount of $175,000 under the Can-Fite License Agreement (as defined below). In addition, that certain exclusive license of Can-Fite’s CF101 drug candidate for the treatment of ophthalmic diseases granted to the Company and that related services agreement was terminated pursuant to a Termination of License Agreement and a Termination of Services Agreement that was entered into;

 

immediately following the Effective Time,  Ron Mayron, Yossi Keret, Dr. Franck Amouyal and Joseph Zarzewsky were appointed to the board of directors of the Company to hold office until the earlier of the next annual meeting where directors will be appointed, such director’s successor is elected and qualified, or until such director’s earlier resignation or removal and following those appointments, Pnina Fishman, Ph.D. Ilan Cohen, Ph.D., Guy Regev and Roger Kornberg, Ph.D. resigned from the board of directors of the Company. Accordingly, the board of directors of the Company consists of five members, Ron Mayron, Yossi Keret, Dr. Franck Amouyal, Joseph Zarzewsky and Michael Belkin, Ph.D.;

 

immediately following the Effective Time, Pnina Fishman, Ph.D., Itay Weinstein and Ronen Kantor resigned as officers of the Company and the newly constituted board appointed Or Eisenberg as Acting Chief Executive Officer, Chief Financial Officer, Treasurer and Secretary and Noam Danenberg as Chief Operating Officer; and

 

Wize Israel ordinary shares were delisted from the Tel Aviv Stock Exchange and there will no longer be a public trading market for Wize Israel ordinary shares in Israel. Company common stock will continue to be quoted on the OTC Pink under the symbol “WIZP”. The Company intends to be quoted on the OTCQB in the near term.

 

4

 

 

Immediately following the completion of the Merger, the pre-Merger Company stockholders continued to hold 10,441,251 shares, or 10% of the issued and outstanding common stock of the Company, and former Wize Israel shareholders own 93,971,259 shares, or 90% of the issued and outstanding common stock of the Company (both percentages excluding (i) shares of common stock issuable upon the exercise of the shares issuable upon conversion of the 2016 Loan Agreement and 2017 Loan Agreement (together, the “Convertible Loans”), (ii) shares of common stock issuable upon the exercise of the future investment rights under the Convertible Loans (the “Future Investment Rights”), (iii) shares of common stock issuable upon the exercise of the PIPE Warrants, and (iv) shares of common stock issuable upon the exercise of certain options held by pre-Merger directors and officers of the Company (the “Company Stock Options”). In the event all the Convertible Loans, Future Investment Rights, PIPE Warrants and Company Stock Options were to be exercised in full, then pre-Merger stockholders and option holders of the Company would own 10,558,751 shares, and their combined ownership percentage would be reduced to approximately 5.4% of the issued and outstanding common stock of the Company, and the former Wize Israel shareholders and holders of Convertible Loans on a combined basis would own 185,589,375 shares, or approximately 94.6% of the issued and outstanding common stock of the Company, assuming, for the purposes of this calculation, a total of 196,148,126 shares of Company common stock issued and outstanding on a fully diluted basis.

 

As a result of the Merger, the business of Wize Israel became the ongoing business of the Company.

 

The Merger is being accounted for as a reverse recapitalization of the Company by Wize Israel. Under reverse recapitalization accounting, the assets and liabilities of the Company will be recorded, as of the completion of the Merger, at their historical amounts. Consequently, the interim consolidated financial information of Wize Israel reflects the operations of the acquirer for accounting purposes together with a deemed issuance of shares, equivalent to the shares held by the former stockholders of the legal acquirer and a recapitalization of the equity of the accounting acquirer. The interim consolidated financial information includes the accounts of Wize Israel since the effective date of the reverse recapitalization and the accounts of the Company since inception.

 

Following the Merger, the Company will continue to be a “smaller reporting company,” as defined in Item 10(f)(1) of Regulation S-K, as promulgated by the SEC.

   

FORM 10 INFORMATION

 

Item 2.01(f) of this Report states that if the Company was a “shell company” (as such term is defined in Rule 12b-2 under the Exchange Act), as the Company was immediately before the Merger, then the Company must disclose the information that would be required if the Company were filing a general form for registration of securities on Form 10. Accordingly, the Company is providing below the information that would be included in a Form 10 if it were to file a Form 10.

 

Business

 

General. Subject to the Recent Developments discussed below, the business of the Company following the Merger is described in the Proxy Statement/Prospectus in the section entitled “ Wize Business Description ” beginning on page 91 and that information is incorporated herein by reference.

 

Recent Developments . The following Recent Developments supersede and modify any information in the “ Wize Business Description ” and “ Risk Factors ” that are incorporated by reference from the Proxy Statement/Prospectus.

 

On September 6, 2017, Resdevco Ltd. (“Resdevco”), the licensor of certain rights to Wize Israel of LO2A under a license agreement (the “LO2A License Agreement”), granted to Wize Israel, sole rights to commercialize LO2A in China. By agreement dated September 25, 2017, Wize Israel and Resdevco agreed that Wize Israel’s sold rights to commercialize LO2A in China shall be limited to one year if by September 6, 2018, Wize Israel has not signed a distribution agreement for LO2A in China.

 

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On October 26, 2017, Wize Israel announced the termination of its single-center trial in Israel that commenced in January 2017 (“Single Center Trial”). The Single Center Trial was a Phase II, randomized, double-blind, placebo-controlled, pilot study carried out in parallel groups that was intended to evaluate the safety and efficacy of LO2A for patients suffering from moderate to severe Conjunctivochalasis (“CCH”), with Wize Israel having sole access to the trial data. On October 24, 2017, Wize Israel received notice from the contract research organization that manages and supervises Wize Israel’s clinical trials ("CRO"), that an inadequate amount of quality information may be derived from the results collected thusfar, given that there is no correlation in the reaction of both eyes to LO2A, in contrast to professional literature and other trials. In addition, the recruitment rate of patients was less than required and there was a higher than expected dropout rate. In light of the above, the CRO concluded that the results of the trial would be of no use even if the trial continued until the end of its term. Based on the CRO’s conclusion, Wize Israel determined to terminate the trial and to save the future costs that would be incurred in connection with such trial. For the avoidance of doubt, this does not impact the multi-center clinical trial that Wize Israel is conducting at five different centers in Israel which commenced in August 2016 (the “Multi-Center Trial”). The Multi-Center Trial is a Phase II randomized, double-blind, placebo-controlled study carried out in parallel groups that is evaluating the safety and efficacy of LO2A for patients suffering from moderate to severe CCH. As of October 26, 2017, the Multi-Center Trial had already enrolled 43 out of the planned 62 patients, with the treatment time for each patient being three months.

 

On November 3, 2017, Wize Israel entered into a framework agreement with a Chinese pharmaceutical company (the “Chinese Distributor”), whereby, subject to the negotiation and execution of a detailed distribution agreement and obtaining necessary regulatory approvals in China, the Chinese Distributor will act as exclusive distributor in China of LO2A. The framework agreement includes, among other things, minimum purchase obligations of the Chinese Distributor, which Wize Israel estimated to range, over the five-year period of the contemplated agreement, between $22.5 million to $39 million. As of the date hereof, no detailed distribution agreement has been entered into with the Chinese Distributor and the regulatory process has not been completed and it is not possible at this stage to determine when these conditions will be completed, if ever, and, even if completed, the final terms of such detailed distribution agreement and the expected revenues therefrom.

 

Wize Israel plans on initiating a Phase II randomized, double-blind, placebo-controlled study in up to 40 patients evaluating the safety and efficacy of LO2A for patients suffering from DES with Sjögren’s syndrome (“Sjögren’s”).

 

Risk Factors

 

The risks associated with the Company’s business following the Merger are described in the Proxy Statement/Prospectus in the section entitled “ Risks Related to OphthaliX Following the Merger ,” “ Risks Related to the Business of Wize ,” “ Risks Related to Wize’s Business and Regulatory Matters ,” “ Risks Related to Wize’s Intellectual Property ,” “ Risks Related to Wize’s Industry Risks ,” and “ Risks Related to Wize’s Operations in Israel ” beginning on page 17 and are all incorporated herein by reference.

 

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Management’s Discussion and Analysis of Financial Condition and Results of Operation.

 

You should read the following discussion and analysis of Wize Israel’s financial condition and results of operations together with “Selected historical consolidated financial information” and Wize Israel’s audited annual consolidated financial statements as of December 31, 2016 and December 31, 2015 and unaudited interim consolidated financial statements as of September 30, 2017 and accompanying notes appearing elsewhere in this Report and in the documents incorporated by reference in this Report. This discussion and analysis contains forward-looking statements that involve risks, uncertainties and assumptions. The actual results may differ materially from those anticipated in these forward-looking statements as a result of certain factors, including, but not limited to, those set forth under “Risk Factors” and elsewhere in this Report. All amounts are in U.S. dollars and rounded.

 

Overview

 

Wize Israel is a clinical-stage biopharmaceutical company currently focused on the treatment of ophthalmic disorders, including dry eye syndrome (“DES”). Wize Israel has in-licensed a formula known as LO2A, a drug developed for the treatment of DES and other ophthalmological illnesses, including CCH and Sjögren’s.

 

Wize Israel has not generated any revenues from operations since its inception and although it anticipates generating some immaterial revenue in Israel and the Ukraine during the first half of 2018, Wize Israel does not currently expect to generate any significant revenues for the foreseeable future, primarily because LO2A is still in early clinical stage development in the markets and for the indications Wize Israel is currently targeting. Although Wize Israel’s operating expenses have decreased from $1,811,000 in the year ended December 31, 2015 to $1,034,000 in the year ended December 31, 2016, in order to finance its current strategic plans, including the conduct of ongoing and future clinical trials as well as further research and development, Wize Israel will require significant additional capital and, assuming Wize Israel will have sufficient liquidity resources, Wize Israel anticipates it will incur significantly higher costs in the foreseeable future.

 

Results of Operations

 

Year Ended December 31, 2016 Compared to Year Ended December 31, 2015

 

    Year Ended
December 31,
 
    2016     2015  
             
Operating expenses:            
Research and development   $ 240,000     $ 1,204,000  
General and administrative     794,000       607,000  
Total operating costs     1,034,000       1,811,000  
Financial expenses, net     105,000       44,000  
Net loss   $ 1,139,000     $ 1,855,000  

 

Revenues

 

Wize Israel did not generate any revenues from operations during the years ended December 31, 2016 and 2015. Wize Israel had no revenues primarily because (1) from the time of the creditors’ arrangement in February 2015 until May 2015, when Wize Israel entered into the LO2A License Agreement, Wize Israel did not conduct any business operations and (2) thereafter, currently, Wize Israel is engaged primarily in research and development.

 

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Operating Expenses

 

Research and development expenses.  Research and development expenses were $240,000 for the year ended December 31, 2016, compared to $1,204,000 for the year ended December 31, 2015, a decrease of $964,000 or 80%. The decrease in research and development expenses is primarily related to the issuance in 2015 by Wize Israel of 873,526 of its ordinary shares (fair value of $801,000) as payment to the consultant that introduced Wize Israel to Resdevco, which amount was partially offset by the increased expenses in 2016, all of which related to the Phase II clinical trials that commenced in August 2016. For more information with respect to the expenses of Wize Israel in connection with entering into the LO2A License Agreement, please see Note 4 of the audited financial statements of Wize Israel filed as Exhibit 99.1 to this Report.

 

General and administrative expenses.  General and administrative expenses were $794,000 for the year ended December 31, 2016, compared to $607,000 for the year ended December 31, 2015, an increase of $187,000 or 31%. The increase in general and administrative expenses during these periods is primarily related to payroll and benefits of $121,000, professional services and consultation of $96,000 and taxes and other expenses of $28,000, which expense increase were partially offset by a decrease of $21,000 in rent and office maintenance and a decrease of $37,000 in directors’ salary and insurance.

 

Financial Expenses, Net . Financial expenses, net were $105,000 for the year ended December 31, 2016 compared to financial expenses, net of $44,000 for the year ended December 31, 2015, a change of $61,000 or 139%. In 2016, the total financial expenses were $181,000, $138,000 of which is amortization of beneficial conversion feature (“BCF”), debt issuance costs related to the 2016 Loan (as defined below) and accrued interest on the 2016 Loan, $38,000 of which is amortization of discount and exchange rate differences related to license purchase obligations pursuant to the Convertible Loans and $5,000 is interest and bank commissions and fees. The total financial expenses of $181,000 in 2016 were reduced by $76,000, which reflects the financial income as a result of the change in the fair value of the derivative liability for the Right to Future Investment. In 2015, all $44,000 in financial expenses were as a result of amortization of discount and exchange rate differences related to license purchase obligations pursuant to the Convertible Loans.

 

Net Loss . As a result of the foregoing, Wize Israel incurred a net loss of $1,139,000 for the year ended December 31, 2016 compared to a net loss of $1,855,000 for the year ended December 31, 2015, a decrease in the net loss of $716,000 or 39%.

 

Nine and Three Months Ended September 30, 2017 Compared to the Nine and Three Months Ended September 30, 2016

 

    Nine Months Ended
September 30,
    Three Months Ended
September 30,
 
    2017     2016     2017     2016  
    Unaudited     Unaudited  
                         
Operating expenses:                        
Research and development   $ 288,000     $ 158,000     $ 107,000     $ 40,000  
General and administrative     760,000       600,000       229,000       226,000  
Total operating costs     1,048,000       758,000       336,000       266,000  
Financial expenses, net     1,016,000       108,000       392,000       51,000  
Net loss   $ 2,064,000     $ 866,000     $ 728,000     $ 317,000  

 

Revenues

 

Wize Israel did not generate any revenues from operations during the nine and three months ended September 30, 2017 and 2016. Wize Israel had no revenues primarily because (1) from the time of the creditors’ arrangement in February 2015 until May 2015, when Wize Israel entered into the LO2A License Agreement, Wize Israel did not conduct any business operations and (2) thereafter, Wize Israel is engaged primarily in research and development.

 

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Operating Expenses

 

Research and development expenses

 

Research and development expenses were $288,000 for the nine months ended September 30, 2017, compared to $158,000 for the nine months ended September 30, 2016, an increase of $130,000 or 82%. The increase in research and development expenses is primarily related to the service of a clinical research organization in connection with clinical trials.

 

Research and development expenses were $107,000 for the three months ended September 30, 2017, compared to $40,000 for the three months ended September 30, 2016, an increase of $67,000 or 168%. The increase in research and development expenses is primarily related to an increase in fees of a clinical research organization in connection with clinical trials.

 

General and administrative expenses

 

General and administrative expenses were $760,000 for the nine months ended September 30, 2017, compared to $600,000 for the nine months ended September 30, 2016, an increase of $160,000 or 26%. The increase in general and administrative expenses during these periods is primarily related to an increase of professional services of $239,000, offset by a decrease in payroll and benefits of $39,000 and directors’ salary and insurance of $47,000, leasing and maintenance of offices of $15,000.

 

General and administrative expenses were $229,000 for the three months ended September 30, 2017, compared to $226,000 for the three months ended September 30, 2016, an increase of $3,000 or 1%. The increase in general and administrative expenses during these periods is immaterial.

 

Financial Expenses, Net

 

Financial expenses, net were $1,016,000 for the nine months ended September 30, 2017 compared to financial expenses, net of $108,000 for the Nine months ended September 30, 2016, a change of $908,000 or 840%. In the first three quarters of 2017, total financial expenses were $1,016,000, with $246,000 resulting from the change in the fair value of derivative liability with respect to the Right to Future Investment, $762,000 of which are amortization of BCF and debt issuance costs for the Convertible Loans and accrued interest on Convertible Loans, and $7,000 are interest and bank commissions and fees.. In the first three quarters of 2016, $22,000 of the financial expenses are as a result of amortization of discount and exchange rate differences on license purchase obligation, $85,000 of which are amortization of BCF and debt issuance costs for 2016 Loan and accrued interest on 2016 Loan, and $1,000 are interest and bank commissions and fees. For information related to the changes in the financial expenses, net refer to Note 10 in the unaudited interim consolidated financial statements as of September 30, 2017 filed as Exhibit 99.2 to this Report.

 

Financial expenses, net were $392,000 for the three months ended September 30, 2017 compared to financial expenses, net of $51,000 for the three months ended September 30, 2016, a change of $341,000 or 668%. During the three months ended September 30, 2017, total financial expenses were $392,000, with $382,000 of which are amortization of BCF and debt issuance costs for 2016 Loan and 2017 Loan and accrued interest on 2016 Loan and 2017 Loan, $5,000 of the financial expenses are as a result of amortization of discount and exchange rate differences on license purchase obligation and $5,000 are interest and bank commissions and fees. During the three months ended September 30, 2016, $6,000 of the financial expenses are as a result of amortization of discount and exchange rate differences on license purchase obligation $49,000 of which are amortization of BCF and debt issuance costs for 2016 Loan and accrued interest on 2016 Loan, and financial income of $4,000 are interest and bank commissions and fees. For information related to the changes in the financial expenses, net refer to Note 10 in the unaudited interim consolidated financial statements as of September 30, 2017 filed as Exhibit 99.2 to this Report.

 

Net Loss

 

As a result of the foregoing, Wize Israel incurred a net loss of $2,064,000 and $728,000 for the nine and three months ended September 30, 2017 compared to a net loss of $866,000 and $317,000 for the nine and three months ended September 30, 2016, an increase in the net loss of $1,198,000 or 138% and an increase in the net loss of $411,000 or 130%.

 

9

 

 

Liquidity and Capital Resources

 

General

 

Liquidity is the ability of a company to generate funds to support its current and future operations, satisfy its obligations, and otherwise operate on an ongoing basis. Significant factors in the management of liquidity are funds generated by operations, levels of accounts receivable and accounts payable and capital expenditures. Since the court-approved creditors arrangement completed in February 2015, Wize Israel financed its operations primarily through equity and convertible debt financings in private placements, as described below.

 

Working Capital and Cash Flows

 

As of December 31, 2016 and December 31, 2015, Wize Israel had $28,000 and $423,000 in cash and cash equivalents ,  respectively. As of September 30, 2017, Wize Israel had $572,000 in cash and cash equivalents.

 

As of September 30, 2017 and December 31, 2016, Wize Israel had $1,082,000 and $406,000 of outstanding loans (including Convertible Loans), including interest and discounts, respectively, all of which relates to the Convertible Loans, as described below.

 

As of September 30, 2017, December 31, 2016 and December 31, 2015, Wize Israel had ($862,000), ($750,000) and $184,000 of working capital (deficit), respectively. As of September 30, 2017, Wize Israel had an accumulated deficit of $25,547,000. The increase in working capital deficit was primarily due to additional loan amounts that have been received during the nine months ended September 30, 2017 by Wize Israel from Ridge, and other lenders through loans (including Convertible Loans) as described below, reclassification of license purchase obligations from being a non-current liability to a current liability, based on the repayment terms under the LO2A License Agreement and increase in accrued expenses due to professional services. Since the LO2A License Agreement relates to an exclusive license to develop LO2A in the United States, Israel, Ukraine and China, and to purchase, market, sell and distribute LO2A in finished product, which product has not yet been approved by the FDA, Wize Israel determined, that the current status of LO2A is in substance an In-Process Research and Development asset (“IPR&D”). As the IPR&D was received by Wize Israel through a direct acquisition and not through a business combination and as it was determined that the IPR&D does not have future alternative use, the acquisition cost, together with the related direct expenses (including the stock-based compensation) are recorded as part of Wize Israel’s R&D expenses.

 

The following table presents the major components of net cash flows (used in) provided by operating, investing and financing activities for the periods presented:

 

    Year Ended
December 31,
 
    2016     2015  
             
Net cash used in operating activities   $ (874,000 )   $ (509,000 )
Net cash used in investing activities   $ (1,000 )   $ (12,000 )
Net cash provided by financing activities   $ 473,000     $ 945,000  

 

Year Ended December 31, 2016 Compared to Year Ended December 31, 2015

 

For the years ended December 31, 2016 and 2015, net cash used in operating activities was $874,000 and $509,000, respectively. The increase in net cash used in operating activities was due to a decrease in net loss of $716,000, a decrease in IPR&D acquired with no alternative use of $1,201,000, an increase in stock-based compensation expenses of $54,000, an increase in amortization of beneficial conversion feature, debts issuance costs and accrued interest on the 2016 Loan of $138,000, a decrease in change in the fair value of derivative liability for Right to Future Investment of $76,000, an increase in other accounts receivable and other accounts payable of $8,000 and a decrease in change in the fair value of license purchase obligations of $5,000.

 

10

 

 

For the years ended December 31, 2016 and 2015, net cash used in investing activities was $1,000 and $12,000, respectively. Cash was used primarily for investments in restricted bank deposits in connection with the Wize Israel’s credit cards in 2015 of $10,000 and purchase of property and equipment of $1,000.

 

For the years ended December 31, 2016 and 2015, net cash provided by financing activities was $473,000 and $945,000, respectively. Cash was provided in 2016 primarily by proceeds of $117,000 that were received from one of the Interim Loans and the net proceeds of $508,000 that were received from the 2016 Loan Agreement. Wize Israel received $1,044,000 of proceeds from shareholders’ investments in 2015. Repayment of the license purchase obligation to Resdevco was $152,000 in 2016 compared to $99,000 in 2015.

 

The following table presents the major components of net cash flows (used in) provided by operating, investing and financing activities for the periods presented:

 

    Nine Months Ended
September 30,
 
    2017     2016  
    Unaudited  
Net cash used in operating activities   $ (983,000 )   $ (655,000 )
Net cash used in investing activities   $ (2,000 )   $ (1,000 )
Net cash provided by financing activities   $ 1,511,000     $ 356,000  

 

Nine Months Ended September 30, 2017 Compared to the Nine Months Ended September 30, 2016

 

For the nine months ended September 30, 2017 and 2016, net cash used in operating activities was $983,000 and $655,000, respectively. The increase in net cash used in operating activities was due to an increase in net loss of $1,198,000, also impacted by an increase in stock-based compensation expenses of $12,000, an increase in amortization of beneficial conversion feature, debts issuance costs and accrued interest on the 2016 Loan and 2017 Loan of $677,000, an increase in change in the fair value of derivative liability for Right to Future Investment of $246,000, a net increase in trade payable of $31,000, a decrease in other account payables of $52,000, an increase in other account receivables of $23,000 and a decrease in foreign currency adjustment related to license purchase obligation of $21,000

 

For the nine months ended September 30, 2017 and 2016, net cash used in investing activities was $2,000 and $1,000, respectively. Cash was used primarily for the purchase of property and equipment.

 

For the nine months ended September 30, 2017 and 2016, net cash provided by financing activities was $1,511,000 and $356,000, respectively. Cash was provided primarily by proceeds from loans from Ridge of $82,000 during the nine months ended September 30, 2017, issuance of Convertible Loans, net of issuance costs of $620,000 during the nine months ended September 30, 2017 compared to $508,000 during the nine months ended September 30, 2016 and issuance of shares of $963,000. In addition, during the nine months ended September 30, 2017, Wize repaid to Resdevco $154,000, a portion of Wize Israel’s minimum obligations under the LO2A License Agreement compared to $152,000 during the nine months ended September 2016.

 

Outlook

 

According to management estimates, liquidity resources as of September 30, 2017 will not be sufficient to maintain Wize Israel’s planned level of operations for the next 12 months. In particular, Wize Israel intends to seek the agreement of the lenders to convert the Convertible Loans into shares before the maturity date and to raise additional funding. However, for a long-term solution, Wize Israel will need to seek additional capital for the purpose of implementing its business strategy and managing its business and developing drugs. Conducting clinical trials and commercializing products is expensive and Wize Israel will need to raise substantial additional funds to achieve its strategic objectives. Wize Israel has not yet generated any revenues from its current operations, and therefore is dependent upon external sources for financing its operations. Wize Israel will require significant additional financing in the near future. Additional financing may not be available on acceptable terms, if at all. Wize Israel’s future capital requirements as well as the ability to obtain financing will depend on many factors, including those listed under “RISK FACTORS – Risks Related to the Business of Wize Israel” beginning on page 23 of the Proxy Statement/Prospectus. As of September 30, 2017, Wize Israel has an accumulated deficit and a shareholders’ deficiency. In addition, during the nine months ended September 30, 2017 and in each of the years ended December 31, 2016 and 2015, Wize Israel reported losses and negative cash flows from operating activities. Wize Israel’s management considered the significance of such conditions in relation to its ability to meet its current and future obligations and determined that such conditions raise substantial doubt about Wize Israel’s ability to continue as a going concern. As such, the opinion of Wize Israel’s independent registered public accounting firm in its audited financial statements as of and for the year ended December 31, 2016 contains an emphasis of matter paragraph regarding substantial doubt about Wize Israel’s ability to continue as a going concern. Substantial doubt about Wize Israel’s ability to continue as a going concern could materially limit Wize Israel’s ability to raise additional funds through the issuance of new debt or equity securities or otherwise. Future reports on Wize Israel’s financial statements may also include an emphasis of matter paragraph with respect to its ability to continue as a going concern.

 

11

 

 

Wize Israel currently has no agreements, arrangements, or understandings with any person to obtain funds through bank loans, lines of credit, or any other sources, other than the 2017 PIPE. Until Wize Israel can generate significant continuing revenues, Wize Israel expects to satisfy its future cash needs through debt or equity financings, or by out-licensing its distribution rights. Wize Israel cannot be certain that additional funding will be available to it on acceptable terms, or at all. If funds are not available, Wize Israel may be required to delay, reduce the scope of, or eliminate one or more of its commercialization efforts.

 

Wize Israel is addressing its liquidity issues by implementing initiatives to raise additional funds as well as other measures that it believes will allow it to continue as a going concern. Such initiatives may include monetizing of its assets, including, following the Merger, to realize the Company’s remaining investment in Can-Fite’s shares.

 

Principal Financing Activities.  The following is a summary of the equity and debt financings conducted by Wize Israel since the Creditors’ Arrangement:

 

In December 2014, an Israeli court approved a creditors arrangement (the “Creditors’ Arrangement”) under the Israeli Companies Law between Wize Israel (then known as Star Night Technologies Ltd.), its creditors and its shareholders, in which Wize Israel was purchased by a group of investors led by Ridge. Upon the completion of the Creditors’ Arrangement, all of Wize Israel’s assets, rights and obligations were transferred to the creditors’ arrangement fund, so that Wize Israel’s equity after the approval of such arrangement was zero and Wize Israel remained a public shell company without any activity, rights or obligations. The Creditors’ Arrangement was completed in February 2015. In connection with the Creditors’ Arrangement, on February 15, 2015, Wize Israel issued 16,615,368 ordinary shares of Wize Israel, in the aggregate, to Ridge, Zrachia, Avner Arazi (“Arazi”) and Amir Bramli (“Bramli”, and together with Ridge, Zrachia and Arazi, the “2015 Investors”), in exchange for their purchase of the public shell for NIS 1,800,000 (approximately $515,000). In addition, on April 7, 2015, for no consideration, the 2015 Investors provided Wize Israel with a capital amount of NIS 4,056,000 (approximately $1,200,000) in cash.

 

As of September 30, 2017, Wize Israel had a total principal and accrued interest balance of NIS 5.1 million (approximately $1.5 million) of loans (including interest) outstanding under the Convertible Loans described below, of which (1) Ridge extended a principal amount of NIS 1.0 million, (2) Rimon Gold extended a principal amount of NIS 3.0 million, and (3) Shimson Fisher (“Fisher”) (not affiliated, to Wize Israel’s knowledge, with Ridge or Rimon Gold) extended a principal amount of NIS 1.0 million. Below is a summary of the material provisions of the Loan Agreements.

 

The 2016 Loan.  On March 20, 2016, Wize Israel entered into a Convertible Loan (as amended on March 30, 2016, the “2016 Loan Agreement”) with Rimon Gold, whereby Rimon Gold extended a loan in the principal amount of up to NIS 2 million (approximately $519,000), which bears interest at an annual rate of 4% (the “2016 Loan”). Pursuant to the 2016 Loan Agreement, as modified by the 2017 Loan Agreement described below, the 2016 Loan has a maturity date of December 31, 2017.

 

Under the 2016 Loan Agreement, Rimon Gold has the right, at its sole discretion, to convert any outstanding portion of the 2016 Loan, but not less than NIS 100,000 (approximately $26,000), into Wize Israel ordinary shares at a conversion price per share of NIS 0.6358 (approximately $0.16), subject to adjustments for stock splits and similar events set forth in the 2016 Loan Agreement. As a result of the Merger and based on the Exchange Ratio, the conversion price per share for the 2016 Loan was adjusted to NIS 0.15 (approximately $0.04).

 

12

 

 

In order to secure its obligations and performance pursuant to the 2016 Loan Agreement, Wize Israel recorded a first priority fixed charge in favor of Rimon Gold on all of Wize Israel’s rights, including its distribution rights, under the LO2A License Agreement, and a first priority floating charge on all of Wize Israel’s rights, title and interest in all of its assets, as they may exist from time to time (the agreements relating to such charges being referred to as the “Security Agreements”).

 

Rimon Gold is entitled, under certain circumstances, to demand repayment of the 2016 Loan, including among others: (i) if Wize Israel breaches or fails to perform or is shown to have made a false statement, under the 2016 Loan Agreement or the Security Agreements; (ii) any failure of Wize Israel to make a timely payment; (iii) upon the appointment of a receiver; (iv) the imposition of a lien on a material asset of Wize Israel; (v) if Wize Israel files a motion to stay proceedings; (vi) upon the expiration or termination of the LO2A License Agreement or if any party is in material breach of the LO2A License Agreement or if any party notifies the other of its intention to terminate the LO2A License Agreement; (vii) an adverse material change; and (viii) upon the non-performance of Wize Israel pursuant to the 2017 Loan Agreement described below.

 

The 2016 Loan Agreement and the Security Agreements contain a number of other restrictive covenants that limit Wize Israel’s operating flexibility. These covenants include, among other things, limitations on the creation of liens; on the incurrence of indebtedness; on dispositions of assets, mergers, acquisitions and other change of control transactions; on changes in the general nature of Wize Israel’s business; restrictions on payments to related parties; restrictions on conducting rights offerings, and on the distribution of dividends.

 

In addition, under the 2016 Loan Agreement, as modified by the 2017 Loan Agreement, Rimon Gold has the right, until the lapse of 18 months following the conversion of the loan granted by Rimon Gold under the 2016 Loan Agreement, to invest up to NIS 3 million, in the aggregate, at an agreed price per share, which was adjusted based on the Exchange Ratio from NIS 0.85 (approximately $0.22) to NIS 0.21 (approximately $0.06), if Wize Israel conducts any equity financing.

 

The 2017 Loan . On January 15, 2017, Wize Israel entered into a Convertible Loan (the “2017 Loan Agreement”) with Ridge, and, by way of entering into assignments and assumption agreements following such date, also with Rimon Gold and Fisher (together, the “2017 Lenders”), whereby each of the lenders extended a loan in the principal amount of up to NIS 1 million (approximately $283,000) and in the aggregate principal amount of up to NIS 3 million (approximately $850,000), which bears interest at an annual rate of 4% (the “2017 Loan”). Pursuant to the 2017 Loan Agreement, the 2017 Loan has a maturity date of December 31, 2017.

 

Under the 2017 Loan Agreement, each of the 2017 Lenders has the right, at its sole discretion, to convert any outstanding portion of the 2017 Loan, but no less than NIS 100,000 (approximately $28,000), that the lender provided to Wize Israel (each such portion converted, the “Converted Loan Amount”) into Wize Israel ordinary shares at a conversion price per share equal to the lower of (1) NIS 1.00 (approximately $0.28) and (2) the lowest price per share of Wize Israel in any offering made by Wize Israel following the date of the 2017 Loan Agreement and through the date of such requested conversion, subject to adjustments for stock splits and similar events set forth in the 2017 Loan Agreement (the “2017 Loan Conversion Price”). As a result of the 2017 PIPE, the 2017 Loan Conversion Price for Rimon Gold, Fisher and Ridge was adjusted to NIS 0.70 (approximately $0.20), and as a result of the Merger, the 2017 Loan Conversion Price of NIS 0.70 (approximately $0.20) was adjusted in accordance with the Exchange Ratio to NIS 0.17 (approximately $0.05).

 

In addition, the 2017 Loan Agreement grants the 2017 Lenders, for a period of 18 months following the conversion of the Converted Loan Amount, the right to make investments in Wize Israel in an amount equal to NIS 1.50 for each NIS 1.00 of its respective Converted Loan Amount, at an agreed price per share equal to 120% of the applicable 2017 Loan Conversion Price.

 

Ridge is entitled, under certain circumstances, to demand repayment of the 2017 Loan, including: (i) if Wize Israel breaches or fails to perform or is shown to have made a false statement, under the 2017 Agreement or the Security Agreements; (ii) any failure of Wize Israel to make a timely payment; (iii) upon the appointment of a receiver; (iv) the imposition of a lien on a material asset of Wize Israel; (v) if Wize Israel files a motion to freeze proceedings; and (vi) an adverse material change.

 

13

 

 

The 2017 Loan contains a number of restrictive covenants that limit Wize Israel’s operating flexibility. These covenants include, among other things, limitations on the creation of liens; on the incurrence of indebtedness; on dispositions of assets, mergers, acquisitions and other change of control transactions; on changes in the general nature of Wize Israel’s business; restrictions on payments to related parties; and on the distribution of dividends.

 

It should be noted that, prior to entering into the 2017 Loan Agreement, Ridge provided the following three loans to Wize Israel, all of which bore interest at an annual rate equal to the interest rates of the Israeli government bonds: (1) NIS 250,000 was extended in November 2016, (2) NIS 300,000 was extended in December 2016 and (3) NIS 200,000 was extended in February 2017 (together, the “Ridge Interim Loans”). On March 30, 2017, after Ridge already provided NIS 250,000 under the 2017 Loan Agreement out of the NIS 1 million committed by Ridge thereunder, Ridge exercised its right to have the Ridge Interim Loans being treated as a portion of the remaining NIS 1 million.

 

In addition, as part of the 2017 Loan Agreement, Wize Israel and the other lenders agreed that (1) the security interests made under the Security Agreements will also serve to secure the loans made by Rimon Gold under the 2017 Loan Agreement, and (2) Rimon Gold will have the right to be repaid the full 2016 Loan prior to any repayment of the 2017 Loan.

 

Rimon Gold and Ridge Consents to the Merger Agreement . In connection with the Merger Agreement, Wize Israel sought and obtained the written consents of Rimon Gold and Ridge to the transactions contemplated by the Merger Agreement. The consent provided by Rimon Gold provided that it is based upon, among other things, the following obligations: (1) following the closing of the Merger Agreement, the Company will assist Rimon Gold with its filing requirements, if any, with the SEC with respect to beneficial ownership and similar reports; and (2) at closing of the Merger Agreement, the Company will execute and deliver to Rimon Gold the an Irrevocable Guaranty and Undertaking (the “Guaranty”).

 

Under the Guaranty, the Company irrevocably guarantees Wize Israel’s obligations to Rimon Gold under the Convertible Loans. In addition, the Guaranty contains a number of restrictive covenants that limit the Company’s operating flexibility. These covenants include, among other things, limitations on the creation of liens; on the incurrence of indebtedness; on dispositions of assets, mergers, acquisitions and other change of control transactions; on changes in the general nature of the Company’s business; and on the distribution of dividends.

 

2017 PIPE . On June 23, 2017, Wize Israel entered into a Private Placement Agreement (the “2017 PIPE Agreements”) with each of Eliahu Peretz (“Peretz”), Yaacov Zrachia (“Zrachia”), Simcha Sadan (“Sadan”) and Jonathan Brian Rubini (“Rubini”, and together with Peretz, Zrachia and Sadan, the “2017 PIPE Investors”). Pursuant to the 2017 PIPE Agreements, the 2017 PIPE Investors invested a total of up to NIS 3.49 million (approximately $1 million) in exchange for a total of 4,985,714 ordinary shares of, at a price per share of NIS 0.70 (approximately $0.20), with Peretz investing NIS 490,000 (approximately $132,000) in exchange for the private placement of 700,000 ordinary shares of Wize Israel (the “Peretz Financing”) and each of Zrachia, Sadan and Rubini (the “Other Investors”) investing NIS 1 million (approximately $282,000) in exchange for the private placement of 1,428,571 ordinary shares of Wize Israel each (together, the “Other Financing”).

 

Subject to the closing of the Merger, Wize Israel also undertook to cause the Company to grant warrants to each of the 2017 PIPE Investors (the “Warrants”), with each Warrant being exercisable into one share of common stock of the Company, with a term of three years from the date of grant. According to the 2017 PIPE Agreements, the number of Warrants and the exercise price thereof will reflect, prior to giving effect to an adjustment based on the exchange ratio, (i) 735,000 warrants to Peretz and (ii) 1,500,000 warrants to each of the Other Investors, each warrant exercisable into one ordinary share of Wize Israel, at an exercise price of NIS 1.20 per share (approximately $0.34). Based on the Exchange Ratio, Peretz was granted 3,046,266 Warrants and each of the Other Investors was granted 6,216,869 Warrants, each at an exercise price of $0.082.

 

On June 22, 2017, Ridge provided notice to Wize Israel that it has waived its right to adjust the 2017 Loan Conversion Price in connection with the Peretz Investment. On July 4, 2017, Wize Israel completed the Peretz Investment. However, Ridge did not waive its right to adjust the 2017 Loan Conversion Price in connection with the Other Investments. On July 31, 2017, at a general meeting of the shareholders of Wize Israel, the Other Investments was approved and on August 7, 2017 Wize Israel completed the Other Investments.

 

14

 

 

Contractual Obligations and Commitments

 

As a smaller reporting company, Wize Israel is not required to provide the disclosure required by this item.

 

Off-Balance Sheet Arrangements

 

As of September 30, 2017 and December 31, 2016, Wize Israel does not have any off-balance sheet arrangements, as such term is defined under Item 303 of Regulation S-K, that have or are reasonably likely to have a current or future effect on its financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures or capital resources that is material to investors.

 

Recently Issued Accounting Pronouncements

 

For information with respect to recent accounting pronouncements, see Note 2u to the audited consolidated financial statements of Wize Israel filed as Exhibit 99.1 to this Report.

 

Critical Accounting Policies

 

The preparation of consolidated financial statements requires Wize Israel to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent liabilities at the date of the financial statements and the reported amounts of expenses during the reporting period. Wize Israel’s significant accounting policies, which include its management’s best estimates and judgments, are included in Note 2 to the annual consolidated financial statements of Wize Israel for the year ended December 31, 2016 filed as Exhibit 99.1 to this Report. 

 

Qualitative and Quantitative Disclosures about Market Risk

 

As a smaller reporting company, Wize Israel is not required to provide the disclosure required by this item.

 

Properties

 

The properties of the Company following the Merger are described in the Proxy Statement/Prospectus in the section entitled “ Properties ” on page 112 and is incorporated herein by reference.

 

15

 

 

Security Ownership of Certain Beneficial Owners and Management

 

The following table sets forth information immediately following the Merger regarding the beneficial ownership of the Company’s common stock by (i) those persons who are known to the Company to be the beneficial owner(s) of more than 5% of the Company’s common stock, (ii) each of the Company’s directors and named executive officers, and (iii) all directors and executive officers of the Company as a group. Except as otherwise indicated, the beneficial owners listed in the table below possess the sole voting and dispositive power in regard to such shares and have an address of c/o Wize Pharma Ltd., 5b Hanagar Street, Hod Hasharon, Israel 4527708. As November 16, 2017, immediately following the Merger, there were 104,412,510 shares of Company common stock outstanding.

 

Beneficial ownership is determined in accordance with the rules of the SEC and generally includes voting or investment power with respect to securities.  Shares of common stock of the Company subject to options, warrants, notes or other conversion privileges currently exercisable or convertible, or exercisable within 60 days of the date of this table, are deemed outstanding for computing the percentage of the person holding such option, warrant, notes, or other convertible instrument but are not deemed outstanding for computing the percentage of any other person.  Where more than one person has a beneficial ownership interest in the same shares, the sharing of beneficial ownership of these shares is designated in the footnotes to this table.  Unless otherwise indicated in the footnotes to this table, the Company believes that each of the stockholders named in this table has sole voting and investment power with respect to the shares indicated as beneficially owned.

 

Name and Address of Beneficial Owner   Amount and Nature of Beneficial Ownership     Percent of Class  
5% and Greater Shareholders                
Rimon Gold Assets Ltd. (1)     41,999,710       28.7 %
Ridge Valley Corporation (2)     33,352,640       28.3 %
Yaakov Zerahia  (3)     18,500,195       16.7 %
Simcha Sadan  (4)     16,388,217       14.8 %
Shimshon Fisher  (5)     13,469,281       11.4 %
Jonathan Rubini  (6)     12,137,695       11.0 %
Erez Haver, Adv. in trust for Amir Bramli (7)     8,788,912       8.4 %
Can-Fite BioPharma Ltd. (8)     8,563,254       8.2 %
Erez Haver, Adv. and Yehuda Brami, Adv., in trust for Avner Arazi (9)     6,164,724       5.9 %
Yossef Peretz  (10)     5,947,471       5.5 %
 Named Executive Officers and Directors                
Ron Mayron     630,208       *
Yossi Keret             -  
Dr. Franck Amouyal             -  
Joseph Zarzewsky             -  
Michael Belkin, Ph.D. (11)     52,222         *  
Or Eisenberg             -  
Noam Danenberg (12)     1,401,937       1.3 %
Executive Officers and Directors as a Group (7 Persons)             1.9 %

 

* Represents ownership of less than 1%

 

(1)

Represents (i) 19,970,750 shares of common stock issuable upon the conversion of the Convertible Loans and (ii) 22,028,960 shares of common stock issuable upon the exercise of the Future Investment Rights. Rimon Gold is an Israeli private company wholly owned by the Goldfinger Trust (the "Trust"), whose trustee is Abir Raveh (the "Trustee") and whose beneficiary is Yair Goldfinger.  The Trust directs the management of Rimon Gold, its investment and voting decisions and the Trustee directs the management of the Trust, its investment and voting decisions.  The address of Rimon Gold, the Trust and the Trustee is 32 Habarzel, Tel Aviv, Israel. Mr. Goldfinger does not direct the management of Rimon Gold, the Trust or the Trustee, its investment or voting decisions and disclaims beneficial ownership of the shares reported in this table.

 

(2) Represents (i) 19,853,641 shares of common stock, (ii) 6,097,965 shares of common stock issuable upon the conversion of the Convertible Loans and (iii) 7,401,034 shares of common stock issuable upon the exercise of the Future Investment Rights. Ridge is a Seychelles corporation, whose address is Room 206, Premier Building, P.O Box 332, Victoria, Mahe, Seychelles. Priscilla Julie is the sole director of Ridge and holds the voting and dispositive power of the shares of common stock beneficially owned by Ridge. Noam Danenberg, the Company’s Chief Operating Officer, is also the son-in-law of Mrs. Hanna Harpaz, who owns 49% of Ridge.

 

16

 

 

(3)

Represents (i) 12,283,326 shares of common stock and (ii) 6,216,869 shares of common stock issuable upon the exercise of the PIPE Warrants.  The address for Mr. Zerahia is 10 Tzemach Tzedek Street, Lod, Israel.

 

(4) Represents (i) 10,171,348 shares of common stock and (ii) 6,216,869 shares of common stock issuable upon the exercise of the  PIPE Warrants. The address for Mr. Sadan is Hashunit 10, Herzliya, Israel.
   
(5) Represents (i) 6,068,248 shares of common stock issuable upon the conversion of the Convertible Loans and (ii) 7,401,033 shares of common stock issuable upon the exercise of the Future Investment Rights.  The address of Mr. Fisher is 3 HaRav Shmuel Rozovski Street, Bnei Brak, Israel.
   
(6) Represents (i) 5,920,826 shares of common stock and (ii) 6,216,869 shares of common stock issuable upon the exercise of the PIPE Warrants. The address for Mr. Rubini is 2655 Marston Drive, Anchorage, Alaska 99517.
   
(7) To the knowledge of the Company, the shares of common stock are held by Erez Haver, Adv., who was court-appointed as liquidator of a company affiliated with, and holds such shares in trust for, Amir Bramli. The address of Advocate Erez Haver is APM House, 18 Raoul Wallenberg St., Building D, 6th floor, Tel Aviv, Israel.
   
(8) The address of Can-Fite BioPharma Ltd. is 10 Bareket Street, Kiryat Matalon, P.O. Box 7537, Petah-Tikva, 49170, Israel.
   
(9)

To the knowledge of the Company, the shares of common stock are held by Erez Haver, Adv. and Yehuda Bramli, Adv., who were court-appointed as joint receivers on the assets of, and hold such shares in trust for, Avner Arazi. The address of Advocate Erez Haver is APM House, 18 Raoul Wallenberg St., Building D, 6th floor, Tel Aviv, Israel.

 

(10)

Represents (i) 2,901,205 shares of common stock and (ii) 3,046,266 shares of common stock issuable upon the exercise of the PIPE Warrants. The address of Mr. Peretz is Ben Gurion 88 BLVD., Kiryat Malachi, Israel.

 

(11) Represents 52,222 shares of common stock issuable upon exercise of vested options.
   
(12) The shares of common stock are held by Mr. Danenberg through a company where Mr. Danenberg holds a minority interest and he does not serve as a director or an officer. See footnote 2 above.

 

Directors and Executive Officers

 

The Company’s directors and executive officers following the Merger are described in the Proxy Statement/Prospectus in the section entitled “ Management of OphthaliX Following the Merger ” beginning on page 121 and that information is incorporated herein by reference.

 

Executive Compensation

 

The executive compensation of the Company’s executive officers and directors following the Merger is described in the Proxy Statement/Prospectus in the section entitled “ Management of OphthaliX Following the Merger ” beginning on page 121 and that information is incorporated herein by reference.

 

Certain Relationships and Related Transactions

 

The certain relationships and related party transactions of the Company are described in the Proxy Statement/Prospectus in the section entitled “ Related Party Transactions ” beginning on page 126 and are incorporated herein by reference.

 

17

 

 

Legal Proceedings

 

Legal proceedings of the Company and Wize Israel are described in the Proxy Statement/Prospectus in the section entitled “ Legal Proceedings ” on pages 87 and 112, respectively, and are incorporated herein by reference.

 

Market Price of and Dividends on the Company’s Common Equity and Related Stockholder Matters

 

Market price and dividend information of the Company is described in the Proxy Statement/Prospectus in the section entitled “ Market Price and Dividend Information ” on page 11 and is incorporated herein by reference.

 

Recent Sales of Unregistered Securities

 

The Company has not sold any unregistered securities within the past three years from the Closing Date. The issuance of the shares of the Company’s common stock to the former shareholders of Wize Israel and holders of the Convertible Loans was registered with the SEC on a Registration Statement on Form S-4 (Reg. No. 333-219514) (the “Registration Statement”).

 

Description of Registrant’s Securities

 

The description of the Company’s securities is contained in the Proxy Statement/Prospectus in the section entitled “ Description of OphthaliX Capital Stock ” beginning on page 44 and is incorporated herein by reference. In addition, the disclosure set forth in Item 5.03 of this Report is incorporated herein by reference.

 

Indemnification of Directors and Officers

 

The description of indemnification is contained in “ Item 20. Indemnification of Directors and Officers ” on page II-1 of the Registration Statement filed with the SEC on September 5, 2017 and is incorporated herein by reference. In addition, the disclosure contained in the Proxy Statement/Prospectus in the section entitled “ Director Indemnification and Insurance ” on page 80 is incorporated herein by reference.

 

Financial Statements and Supplementary Data

 

Reference is made to the disclosure set forth under Item 9.01 of this Report concerning certain financial statements and supplementary data, which is incorporated herein by reference.

 

Changes in and Disagreements with Accountants on Accounting and Financial Disclosure

 

Reference is made to the disclosure set forth under Item 4.01 of this Report concerning changes to Wize Israel’s independent registered public accounting firm, which is incorporated herein by reference.

 

Financial Statements and Exhibits

 

Reference is made to the disclosure set forth under Item 9.01 of this Report listing financial statements incorporated by reference and exhibits required by Item 601 of Regulation S-K.

 

Item 2.03 Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant.

 

As a result of the Merger, Wize Israel became a wholly-owned subsidiary of the Company. Wize Israel is party to the Convertible Loans described above.

 

Item 3.03. Material Modifications to Rights of Security Holders.

 

The disclosure set forth in Items 2.01 and 5.03 to this Report is incorporated into this item by reference.

 

18

 

 

Item 4.01 Changes in Registrant’s Certifying Accountant

 

Kost Forer Gabbay & Kasierer, a member of Ernst & Young Global (“EY”), the Company’s pre-Merger independent registered public accounting firm since 2011 will continue to serve as the Company’s independent registered public accounting firm. Accordingly, Fahn Kanne & Co. Grant Thornton Israel (“Grant Thornton”), the independent registered public accounting firm of Wize Israel was deemed to be dismissed effective upon the closing of the Merger.

 

None of the reports of Grant Thornton on Wize Israel’s financial statements for either of the past two years or subsequent interim period contained an adverse opinion or disclaimer of opinion, or was qualified or modified as to uncertainty, audit scope or accounting principles, except that Grant Thornton’s report on Wize Israel’s audited financial statements for the years ended December 31, 2016 and 2015, included an emphasis of matter paragraph indicating that there is substantial doubt about Wize Israel’s ability to continue as a going concern.

 

During Wize Israel’s two most recent years ended December 31, 2016 and 2015, and the subsequent interim periods preceding their dismissal, there were (i) no disagreements with Grant Thornton, whether or not resolved, on any matter of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which, if not resolved to the satisfaction of Grant Thornton, would have caused them to make reference to the subject matter of the disagreement in connection with their report on Wize Israel’s financial statements and (ii) no reportable event (as described in paragraph 304(a)(1)(v)) of Regulation S-K).

 

During the two most recent fiscal years and the interim periods preceding the engagement, and through the date of this Report, neither Wize Israel nor anyone on its behalf has previously consulted with EY regarding either (a) the application of accounting principles to a specified transaction, either completed or proposed; or the type of audit opinion that might be rendered on Wize Israel’s financial statements, and neither a written report was provided nor oral advice was provided to Wize Israel that concluded was an important factor considered by Wize Israel in reaching a decision as to the accounting, auditing or financial reporting issue; or (b) any matter that was either the subject of a disagreement (as defined in paragraph 304(a)(1)(iv) of Regulation S-K and the related instructions thereto) or a reportable event (as described in paragraph 304(a)(1)(v)) of Regulation S-K).

 

The Company provided Grant Thornton with a copy of the disclosures it is making in this Report and has requested that Grant Thornton furnish it with a letter addressed to the SEC stating whether they agree with the above statements. A copy of Grant Thornton’s letter is filed herewith as Exhibit 16.1.

  

Item 5.01. Changes in Control of Registrant.

 

As a result of the Merger, the Company experienced a change in control with the former shareholders of Wize Israel effectively acquiring control of the Company. The disclosure set forth in Item 2.01 to this Report is incorporated into this item by reference.

 

Item 5.02. Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers.

 

The disclosure set forth in Item 2.01 to this Report is incorporated into this item by reference.

 

Item 5.03. Amendments to Articles of Incorporation or Bylaws.

 

Prior to the consummation of the Merger, on November 15, 2017, the Company filed an amendment to its Certificate of Incorporation changing its name to “Wize Pharma, Inc.” and increasing the authorized shares of common stock from 100,000,000 to 500,000,000.

 

The foregoing description of the amendment to the Company’s Certificate of Incorporation is qualified entirely by reference to the full text of the Certificate of Amendment of Certificate of Incorporation which is attached hereto as Exhibit 3.3 and is incorporated by reference herein.

 

Item 5.06. Change in Shell Company Status.

 

Prior to the Merger, the Company was a “shell company” as such term is defined in Rule 12b-2 under the Exchange Act. As a result of the Merger, the Company ceased being a “shell company.” Reference is made to the disclosure in the Proxy Statement/Prospectus in the sections entitled “The Merger ” beginning on page 59 and “ The Merger Agreement ” beginning on page 73, which is incorporated herein by reference. Further reference is made to the information contained in Item 2.01 to this Report. The information contained in this Report as filed with the SEC, constitute the current “Form 10 information” necessary to satisfy the conditions contained in Rule 144(i)(2) under the Securities Act.

 

19

 

 

Item 7.01. Regulation FD Disclosure.

 

On November 21, 2017, the Company posted a corporate presentation on the Company’s website at www.wizepharma.com, a copy of which is furnished as Exhibit 99.4 hereto, pursuant to Item 7.01 of Form 8-K.

 

In accordance with General Instruction B.2 of Form 8-K, the information furnished pursuant to this Item 7.01, and including Exhibit 99.4 furnished herewith, shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, nor shall it be deemed incorporated by reference in any filing under the Securities Act or the Exchange Act, except as shall be expressly set forth by specific reference in any such filing.

 

Item 9.01. Financial Statement and Exhibits.

 

(a)-(b) Financial Statements .

 

The Consolidated Financial Statements as of December 31, 2016 and 2015 of Wize Israel are incorporated herein by reference from the Consolidated Financial Statements contained in the Proxy Statement/Prospectus beginning on page F-35.

 

The Unaudited Consolidated Financial Statements as of September 30, 2017 of Wize Israel are filed in this Report as Exhibit 99.2.

 

The Unaudited Pro Forma Consolidated Financial Statements are filed in this Report as Exhibit 99.3.

 

(c) Shell Company Transactions .

 

Reference is made to Items 9.01(a) and 9.01(b) and the exhibits referred to therein, which are incorporated herein by reference.

 

(d) Exhibits.

 

Exhibit

Number

  Description
2.1†   Agreement and Plan of Merger, dated as of May 21, 2017, by and among the Company, Bufiduck Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on May 22, 2017)
     
2.2   Amendment No. 1 to Agreement and Plan of Merger, dated as of October 31, 2017, by and among the Company, Bufiduck Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on November 1, 2017)
     
2.3   Acquisition Agreement, dated November 21, 2011, with Can-Fite Biopharma Ltd. (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on November 23, 2011)
     
2.4   Agreement and Plan of Merger, dated February 24, 2012 (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on April 5, 2012)
     
2.5   Delaware Certificate of Merger (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on April 5, 2012)
     
2.6   Nevada Articles of Merger (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on April 5, 2012)

 

20

 

 

3.1   Certificate of Incorporation (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on April 5, 2012)
     
3.2   Certificate of Amendment to Certificate of Incorporation (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on July 18, 2013)
     
3.3#   Certificate of Amendment to Certificate of Incorporation dated November 15, 2017
     
3.4   Bylaws (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on May 10, 2013)
     
10.1   Stock Purchase Agreement, dated November 21, 2011, with Can-Fite Biopharma Ltd. (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on November 23, 2011)
     
10.2+   2012 Stock Incentive Plan (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on February 9, 2012)
     
10.3+   2012 Stock Incentive Plan, Annex A (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on March 8, 2013)
     
10.4   Agreement dated July 1, 2013, with Michael Belkin (Incorporated by reference to Company’s Registration Statement on Form S-1 filed July 2, 2013)
     
10.5   Form of Stock Purchase Agreement (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on May 22, 2017)
     
10.6   Form of Termination of License Agreement (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on May 22, 2017)

 

10.7   Form of Termination of Services Agreement (Incorporated by reference to Company’s Current Report on Form 8-K filed with the SEC on May 22, 2017)
     
10.8   Exclusive Distribution and Licensing Agreement dated May 1, 2015 between Resdevco Ltd. and Wize Pharma Ltd. (formerly Star Night Technologies Ltd.) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.9   Amendment to Licensing Agreement dated November 22, 2015 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.10   Amendment No. 2 to Licensing Agreement dated March 20, 2016 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.11   Amendment No. 1 to Licensing Agreement – Israeli Market dated May 31, 2016 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.12   Amendment No. 2 to Licensing Agreement – Ukraine Market dated May 31, 2016 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.13   Addition to Amendment to Licensing Agreement dated January 6, 2017 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)

 

21

 

 

10.14   Second Addition to Amendment to Licensing Agreement dated March 30, 2017 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.15   Correction to Licensing Agreement dated June 16, 2017 between Resdevco Ltd. and Wize Pharma Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.16   Appendix F to Exclusive Distribution and Licensing Agreement between Resdevco Ltd. and Wize Pharma Ltd. signed on May 1, 2015 dated July 20, 2017 (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.17   Appendix G to Exclusive Distribution and Licensing Agreement between Resdevco Ltd. and Wize Pharma Ltd. signed on May 1, 2015 dated July 20, 2017 (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.18   Assumption Agreement dated August 30, 2016 between Resdevco Ltd. and OcuWize Ltd (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.19   Convertible Loan Agreement dated March 20, 2016 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.20   Addendum to Convertible Loan Agreement dated March 30, 2016 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.21   Second Convertible Loan Agreement dated January 12, 2017 between Wize Pharma Ltd. Ridge Valley Corporation and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.22   Debenture Floating Charge dated March 20, 2016 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.23   Debenture - Fixed Charge dated March 20, 2016 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.24   Debenture Floating Charge dated October 26, 2016 between Ocu Wize Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.25   Debenture – Fixed Charge dated October 26, 2016 between Ocu Wize Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)

 

10.26   Amendment to Debenture – Floating Charge dated March 28, 2017 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.27   Amendment to Debenture – Fixed Charge dated March 28, 2017 between Wize Pharma Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)

 

22

 

 

10.28   Amendment to Debenture – Floating Charge dated March 28, 2017 between Ocu Wize Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.29   Amendment to Debenture – Fixed Charge dated March 28, 2017 between Ocu Wize Ltd. and Rimon Gold Assets Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.30   Form of Irrevocable Guaranty and Undertaking (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.31   Private Placement Agreement dated May 25, 2017 between Wize Pharma Ltd. and Jonathan Brian Rubini (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.32   Addendum to Private Placement Agreement dated June 15, 2017 between Wize Pharma Ltd. and Jonathan Brian Rubini (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.33   Private Placement Agreement dated June 23, 2017 between Wize Pharma Ltd. and Simcha Sadan (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.34   Private Placement Agreement dated June 23, 2017 between Wize Pharma Ltd. and Yaacov Zrachia (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.35   Private Placement Agreement dated June 23, 2017 between Wize Pharma Ltd. and Peretz Yosef Eliahu (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.36+   Employment Agreement dated September 30, 2015 between Wize Pharma Ltd. and Or Eisenberg (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.37+   Agreement for Provision of Services Agreement dated September 30, 2015 between Wize Pharma Ltd. and N Danenberg Holdings (2000) Ltd. (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
   
10.38+   Agreement for Provision of Services Agreement dated September 30, 2015 between Wize Pharma Ltd. and Ron Mayron (unofficial English translation from Hebrew) (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)
     
10.40   Finder’s Agreement dated June 19, 2017 between Wize Pharma Ltd. and Harbin Israel (Trading) Ltd. (Incorporated by reference to Company’s Registration Statement on Form S-4 filed with the SEC on July 27, 2017)

 

23

 

 

10.41#   Letter dated September 6, 2017 from Resdevco Ltd.
     
10.42#   Agreement dated September 25, 2017 between Resdevco Ltd. and Wize Pharma Ltd.
     
16.1#   Letter dated November 21, 2017 from Fahn Kanne & Co. Grant Thornton Israel as to the change in certifying accountant
     
21.1#   Subsidiaries of the Company
     
99.1   Audited financial statements of Wize Pharma Ltd. as of and for the fiscal years ended December 31, 2016 and 2015 (Incorporated by reference to Company’s Proxy Statement/Prospectus filed with the SEC on September 8, 2017)
     
99.2#   Unaudited consolidated financial statements of Wize Pharma Ltd. as of and for the three and nine months ended September 30, 2017 and 2016
     
99.3#   Unaudited Pro Forma Consolidated Financial Statements for the fiscal year ended December 31, 2016 and as of and for the nine months ended September 30, 2017
     
99.4#   Corporate Presentation dated November 2017

 

  # Filed herewith

 

  Exhibits and schedules to this exhibit have been omitted pursuant to Item 601(b)(2) of Regulation S-K. The Company will furnish the omitted exhibits and schedules to the Securities and Exchange Commission upon request by the Securities and Exchange Commission.

 

  + Management compensatory plan

 

24

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Company has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

  Wize Pharma, Inc.
     
Date:  November 21, 2017 By: /s/ Or Eisenberg           

  Name: Or Eisenberg
Title: Acting Chief Executive Officer,
Chief Financial Officer, Treasurer and Secretary

 

 

25

 

 

Exhibit 3.3

 

State of Delaware    
Secretary of State    
Division of Corporations    
Delivered 02:09 PM 11/15/2017 CERTIFICATE OF AMENDMENT  
FILED 02:09 PM 11/15/2017 OF  
SR 20177100985 - File Number 5081043 CERTIFICATE OF INCORPORATION
OF
OPHTHALIX INC.
(A Delaware Corporation)
 

 

OPHTHALIX INC., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware, (the “Corporation”), in accordance with the provisions of Section 242 of the General Corporation Law of the State of Delaware, does hereby certify:

 

FIRST: That upon filing of this Certificate of Amendment, Article I of the Certificate of Incorporation is hereby amended and restated in its entirety as follows:

 

“The name of the corporation is Wize Pharma, Inc.”

 

SECOND: That upon filing of this Certificate of Amendment, Section 3.1(i) of Article III of the Certificate of Incorporation of the Corporation is hereby amended and restated in its entirety such that, as amended, said section shall read in its entirety as follows:

 

“(i) The total number of shares of stock which the Corporation shall have authority to issue is 500,000,000 shares of common stock, par value $.001 per share, and 1,000,000 shares of preferred stock, par value $.001 per share.”

 

THIRD: This Certificate of Amendment was duly adopted in accordance with Section 242 of the DGCL. The Board of Directors duly adopted resolutions setting forth and declaring advisable this Certificate of Amendment and directed that the proposed Amendment be considered by the stockholders of the Corporation. A meeting of stockholders was duly called upon notice in accordance with Section 222 of the DGCL and held on October 10, 2017, at which meeting the necessary number of shares were voted in favor of the proposed amendment. The stockholders of the Corporation duly adopted this Certificate of Amendment.

 

FOURTH: The remaining provisions of the Certificate of Incorporation, including without limitation the remaining provisions of Article III, are not affected by the aforementioned amendment and remain in full force and are not affected by this Certificate of Amendment.

 

IN WITNESS WHEREOF, said Corporation has caused this certificate to be signed by its interim Chief Executive Officer this 15th day of November, 2017.

 

  OPHTHALIX INC.
  a Delaware corporation
   
  By: /s/ Pnina Fishman
    Pnina Fishman, Interim CEO

 

 

 

 

Exhibit 10.41

 

RESDEVCO LTD.

 

 

September 6, 2017

 

To whom it may concern,

 

Resdevco, the developer and owner of the IP of LO2A eye drops, has granted Wize Pharma Ltd. the sole rights to commercialize LO2A in China.

 

/s/ Prof S. Dikstein

Prof S Dikstein,

CEO and Founder

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

P.O.B. 3338, Jerusalem, Israel

Tel. and Fax: 972-2-6524734

 

 

 

Exhibit 10.42

 

RESDEVCO LTD.

 

 

Commercialization Rights of LO2A in China

 

Resdevco Ltd. and Wize Pharma Ltd. hereby agree that Wize Pharma’s sole rights to commercialize LO2A in China, as declared in the letter from Resdevco, dated, September 6, 2017, shall be limited to one year if by September 6, 2018, Wize Pharma has not signed a distribution agreement of LO2A eye drops in China.

 

/s/ Prof. S. Dikstein   September 25, 2017
Resdevco Ltd   Date
     
/s/ Wize Pharma Ltd.   September 25, 2017
Wize Pharma Ltd.   Date

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

P.O.B. 3338, Jerusalem, Israel

Tel. and Fax: 972-2-6524734

 

Exhibit 16.1

 

U.S. Securities and Exchange Commission

Office of the Chief Accountant

100 F Street, NE

Washington, DC 20549

USA

 

Re: Wize Pharma, Inc. (formerly OphthaliX, Inc.)

File No. 000-52545

Fahn Kanne & Co.

Head Office

32 Hamasger Street

Tel-Aviv 6721118, ISRAEL

PO Box 36172, 6136101

 

T +972 3 7106666

F +972 3 7106660

www.gtfk.co.il

Tel-Aviv, November 21, 2017

 

 
   

 

Ladies and Gentlemen:

We have read Item 4.01 of Form 8-K of Wize Pharma, Inc. (formerly OphthaliX, Inc.) dated November 21, 2017, and agree with the statements concerning our Firm contained therein.

Very truly yours,

 

 

/s/ FAHN KANNE & CO. GRANT THORNTON ISRAEL

 

 

 

 

Certified Public Accountants

Fahn Kanne & Co. is the Israeli member firm of Grant Thornton International Ltd.

Exhibit 21.1

 

Subsidiaries of Wize Pharma, Inc.

 

Name of Subsidiary   Jurisdiction of Incorporation or Organization
     
Wize Pharma Ltd.   Israel
     
Wizecon Bio, Inc. (wholly owned by Wize Pharma Ltd.)   Delaware
     
OcuWize Ltd. (wholly owned by Wize Pharma Ltd.)   Israel

 

Exhibit 99.2

  

 

 

WIZE PHARMA LTD.

 

INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

AS OF SEPTEMBER 30, 2017

 

U.S. DOLLARS IN THOUSANDS

 

UNAUDITED

 

INDEX

 

  Page
   
Consolidated Balance Sheets 2-3
   
Consolidated Statements of Comprehensive Loss 4
   
Consolidated Statements of Changes in Shareholders’ Deficit 5
   
Consolidated Statements of Cash Flows 6
   
Notes to Unaudited Interim Consolidated Financial Statements 7 - 27

 

- - - - - - - - - - - - - -

 

 

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

CONSOLIDATED BALANCE SHEETS

U.S. dollars in thousands

  

   

As of

September 30,

    As of December 31,  
    2017     2016  
    Unaudited        
ASSETS            
             
CURRENT ASSETS:            
Cash and cash equivalents   $       572     $       28  
Restricted bank deposit     11       10  
Other accounts receivable     45       29  
                 
Total current assets     628       67  
                 
NON-CURRENT ASSETS:                
                 
Property and equipment, net     3       2  
                 
TOTAL ASSETS   $ 631     $ 69  

 

The accompanying notes are an integral part of the unaudited interim consolidated financial statements.

 

  2  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

CONSOLIDATED BALANCE SHEETS

U.S. dollars in thousands (except share data)

 

   

As of

September 30,

    As of December 31,  
    2017     2016  
    Unaudited        
             
LIABILITIES AND SHAREHOLDERS’ DEFICIT            
             
CURRENT LIABILITIES:            
Trade payables   $ 44     $ 13  
Other accounts payable     221       214  
Current portion of license purchase obligation (Note 4)     143       150  
Convertible loans, net (Note 5)     1,082       289  
Loans from controlling shareholder (Note 6)     -       117  
Derivative liability for right to future investment (Notes 5 and 7)     -       34  
                 
Total current liabilities     1,490       817  
                 
LICENSE PURCHASE OBLIGATION, NET (Note 4)     -       83  
                 
COMMITMENTS AND CONTINGENCIES (Note 8)                
                 
SHAREHOLDERS’ DEFICIT:                
                 
Ordinary Shares, with no par value per share -                
1,000,000,000 shares authorized at September 30, 2017 (unaudited) and December 31, 2016; 22,491,240 and 17,505,526 shares issued and outstanding at September 30, 2017 (unaudited) and December 31, 2016, respectively     *) -     *) -
Additional paid- in capital     25,481       23,394  
Treasury shares     (747 )     (747 )
Accumulated other comprehensive income (loss)     (46 )     5  
Accumulated deficit     (25,547 )     (23,483 )
                 
Total shareholders’ deficit     (859 )     (831 )
                 
TOTAL LIABILITIES AND SHAREHOLDERS’ DEFICIT   $ 631     $ 69  

 

*)       Representing an amount less than $1

  

The accompanying notes are an integral part of the unaudited interim consolidated financial statements.

 

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WIZE PHARMA LTD. AND SUBSDIARY

 

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS

U.S. dollars in thousands (except share and per share data)

 

   

Nine months ended

September 30,

   

Three months ended

September 30,

   

Year ended

December 31,

 
    2017     2016     2017     2016     2016  
    Unaudited        
                               
Operating expenses:                              
Research and development   $ 288     $ 158     $ 107     $ 40     $ 240  
General and administrative     760       600       229       226       794  
                                         
Total operating expenses     1,048       758       336       266       1,034  
                                         
Financial expenses, net (Note 10)     1,016       108       392       51       105  
                                         
Net loss   $ 2,064     $ 866     $ 728     $ 317     $ 1,139  
                                         
Other comprehensive (income) loss:                                        
Foreign currency translation adjustments     51       10       (30 )     10       (3 )
                                         
Other comprehensive (income) loss     51       10       (30 )     10       (3 )
                                         
Comprehensive loss     2,115       876       698       327       1,136  
                                         
Basic and diluted net loss per share   $ 0.11     $ 0.05     $ 0.03     $ 0.02     $ 0.07  
                                         
Weighted average number of Ordinary Shares used in computing basic and diluted net loss per share     18,582,045       17,504,734       20,724,828       17,504,734       17,504,734  

 

The accompanying notes are an integral part of the unaudited interim consolidated financial statements.

 

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WIZE PHARMA LTD. AND SUBSDIARY

 

CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS’ DEFICIT

U.S. dollars in thousands (except share data)

  

    Ordinary Shares   Additional paid-in    

Treasury

    Accumulated other comprehensive     Accumulated     Total shareholders’  
    Number     Amount   capital     shares     income (loss)     deficit     deficit  
                                         
Balance as of January 1, 2016     17,505,526     $     * ) -   $ 23,083     $ (747 )   $ 2     $ (22,344 )   $ (6 )
                                                       
Beneficial conversion feature in respect to convertible loan (Note 5)     -       -     246       -       -       -       246  
Stock-based compensation     -       -     65       -       -       -       65  
Other comprehensive income     -       -     -       -       3       -       3  
Net loss     -       -     -       -       -       (1,139 )     (1,139 )
                                                       
Balance as of December 31, 2016     17,505,526       *) -     23,394       (747 )     5       (23,483 )     (831 )
                                                       
Beneficial conversion feature in respect to convertible loan (Note 5)     -       -     811       -       -       -       811  
Classification of derivative liability for right to future investment into equity (Note 7)     -       -     280       -       -       -       280  
Issuance of units consisting of ordinary shares and detachable warrants, net of issuance costs (Note 9a)     4,985,714       *) -     963       -       -       -       963  
Stock-based compensation     -       -     33       -       -       -       33  
Other comprehensive loss     -       -     -       -       (51 )     -       (51 )
Net loss     -       -     -       -       -       (2,064 )     (2,064 )
                                                       
Balance as of September 30, 2017 (unaudited)     22,491,240     $     * ) -   $ 25,481     $ (747 )   $ (46 )   $ (25,547 )   $ (859 )

 

*)       Representing an amount less than $1

  

The accompanying notes are an integral part of the unaudited interim consolidated financial statements.

 

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WIZE PHARMA LTD. AND SUBSDIARY

 

CONSOLIDATED STATEMENTS OF CASH FLOWS

U.S. dollars in thousands

 

   

Nine months ended

September 30,

 
    2017     2016  
    Unaudited  
             
Cash flows from operating activities            
             
Net loss   $ (2,064 )   $ (866 )
Adjustments to reconcile net loss to net cash used in operating activities:                
Depreciation     *) -     *) -
Stock-based compensation     33       21  
Amortization of discounts resulting from beneficial conversion feature and derivative liability and debt issuance costs related to convertible loans     729       75  
Accrued interest on convertible loans     33       10  
Change in the fair value of derivative liability for Right to Future Investment     246       -  
Foreign currency adjustments related to license purchase obligation     1       22  
Change in:                
Other accounts receivable     (28 )     (5 )
Trade payables     30       (1 )
Other accounts payable and license purchase obligation     37       89  
                 
Net cash used in operating activities     (983 )     (655 )
                 
Cash flows from investing activities                
                 
Purchase of property and equipment     (2 )     (1 )
                 
Net cash used in investing activities     (2 )     (1 )
                 
Cash flows from financing activities                
                 
Proceeds from loans from controlling shareholder     82       -  
Proceeds from issuance of convertible loans, net of issuance costs (Note 5)     620       508  
Repayment of license purchase obligation     (154 )     (152 )
Proceeds from issuance of units consisting of ordinary shares and detachable warrants, net of issuance costs (Note 9a)     963       -  
                 
Net cash provided by financing activities     1,511       356  
                 
Foreign currency translation adjustments on cash and cash equivalents     18       9  
                 
Increase (decrease) in cash and cash equivalents     544       (291 )
Cash and cash equivalents at the beginning of the period     28       423  
                 
Cash and cash equivalents at the end of the period   $ 572     $ 132  
                 
Supplemental disclosure of non-cash financing activities:                
                 
Classification of derivative liability for Right to Future Investment into equity (Notes 5 and 7)   $ 280     $ -  
                 
Conversion of bridge loans from controlling shareholder to convertible loans (Note 6)   $ 206     $ -  

 

The accompanying notes are an integral part of the unaudited interim consolidated financial statements.

 

  6  

 

  

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 1:- GENERAL

 

  a. Wize Pharma Ltd. (the “Company” or “Wize”) was incorporated in Israel in 1982 as a public company by the name of “Eitam Eretz Israel Advanced Industries Ltd.” In September 1987, the Company’s shares were listed for trading on the Tel Aviv Stock Exchange (“TASE”). In June 2015, the Company changed its name to Wize Pharma Ltd.

 

The Company is a clinical-stage biopharmaceutical company currently focused on the treatment of ophthalmic disorders, including dry eye syndrome (“DES”). In May 2015, soon after the completion of the Creditors’ Arrangement (see also Note 1b), the Company entered into an Exclusive Distribution and Licensing Agreement (as amended, the “License Agreement”) with Resdevco Ltd. (“Resdevco”), whereby Resdevco granted to Wize an exclusive license to purchase, market, sell and distribute a formula known as LO2A (“LO2A” or the “Product”) in the United States, Israel, Ukraine and China as well as a contingent right to do the same in other countries. LO2A is a drug developed for the treatment of DES, and other ophthalmological illnesses, including Conjunctivochalasis (“CCH”) and Sjögren’s syndrome (“Sjögren’s”) (see also Note 4 to the annual consolidated financial statements as of December 31, 2016).

 

Commencing August 30, 2016, the Company manages its activity through a wholly-owned Israeli Subsidiary (“Subsidiary”), which manages and develops all of the activity under the License Agreement. The Company and the Subsidiary are referred to herein as a “Group”.

 

  b. Developments Pertaining to the Company’s Former Activity and Completion of Creditors’ Arrangement

 

On December 4, 2014, an Israeli court approved a creditors arrangement (the “Creditors’ Arrangement”) under the Israeli Companies Law between Wize (then known as Star Night Technologies Ltd.), its creditors and its shareholders, in which Wize was purchased by a group of investors led by Ridge Valley Corporation (“Ridge”). Upon the completion of the Creditors’ Arrangement, all of Wize’s assets, rights and obligations were transferred to the creditors’ arrangement fund, so that Wize’s equity after the approval of such arrangement was zero and Wize remained a public shell company without any activity, rights or obligations.

 

Pursuant to the Creditors’ Arrangement, the Company was exempted from all of its liabilities to creditors, and the Company recorded a gain in an amount of NIS 13,576,000 (approximately $3,407, based on the exchange rate reported by the Bank of Israel on December 4, 2014) from the Creditors’ Arrangement which was recognized in the Company’s consolidated statements of comprehensive loss for the year ended December 31, 2014.

 

  7  

 

  

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 1:- GENERAL (Cont.)

 

  c. Going concern uncertainty and management plans

 

Following the completion of the Creditors’ Arrangement, the Company commenced operations as a clinical-stage biopharmaceutical company, and as described in Note 4 to the annual consolidated financial statements as of December 31, 2016, the Company purchased an exclusive license to purchase, market, sell and distribute LO2A in the United States, Israel and Ukraine as well as a contingent right to do the same in other countries.

 

The registration process in certain countries, including the United States, and the commercialization of the Company’s products is expected to require substantial expenditures.  The Company has not yet generated any revenues from its current operations, and therefore is dependent upon external sources for financing its operations. As of September 30, 2017, the Company has an accumulated deficit in an amount of $25,547 and a shareholders’ deficit in an amount of $859. In addition, for the nine month period ended September 30, 2017, the Company reported losses and negative cash flows from operating activities.  Management considered the significance of such conditions in relation to the Company’s ability to meet its current and future obligations and determined that such conditions raise substantial doubt about the Company’s ability to continue as a going concern.  The accompanying interim consolidated financial statements do not include any adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classification of liabilities that may result from the possible inability of the Company to continue as a going concern.

 

Until such time as the Company generates sufficient revenue to fund its operations (if ever), the Company plans to finance its operations through the sale of equity or equity-linked securities and/or debt securities and, to the extent available, short-term and long-term loans. There can be no assurance that the Company will succeed in obtaining the necessary financing to continue its operations as a going concern.

 

  d. Agreement and plan of merger:

 

On May 21, 2017, Wize Pharma, Inc. (formerly, known as OphthaliX, Inc.), a Delaware corporation (“OphthaliX”), Wize and Bufiduck Ltd., a company formed under the laws of the State of Israel and a wholly owned subsidiary of OphthaliX (“Merger Sub”), entered into an agreement and plan of merger (as may be amended from time to time, the “Merger Agreement”) that provides for, among other things, the merger of Merger Sub with and into Wize, with Wize continuing as the surviving entity and becoming a wholly owned subsidiary of OphthaliX, on the terms and conditions set forth in the Merger Agreement (the “Merger”). On November 16, 2017, the Merger was completed (see Note 12d). Prior to the Merger, 82% of the outstanding shares of common stock was held by Can-Fite Biopharma Ltd. Prior to the Merger, OphthaliX had no active business operations and was deemed to be a “shell company” as defined in Rule 12b-2 of the Exchange Act.

 

  8  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 1:- GENERAL (Cont.)

  

Subject to the terms and conditions of the Merger Agreement, holders of outstanding Wize ordinary shares (collectively referred to herein as the Wize shareholders) were entitled to receive 4.1445791236989 shares of OphthaliX common stock for each Wize ordinary share they held (following adjustments set forth in the Merger Agreement, the “Exchange Ratio”), or an aggregate of 93,971,259 shares of OphthaliX common stock at closing. Immediately following the effective time of the Merger (the “Effective Time”), pre-merger Wize shareholders owned approximately 90% of the outstanding common stock of OphthaliX while pre-merger OphthaliX stockholders owned the remaining approximate 10%. At the Effective Time, pre-merger OphthaliX stockholders will continue to own and hold their existing shares of OphthaliX common stock. Each convertible note to purchase Wize ordinary shares existing at the time of the Merger Agreement (the “Convertible Loans”) will constitute a convertible note to purchase the number of shares of OphthaliX common stock equal to the number of Wize ordinary shares that were subject to a Convertible Loan immediately prior to the Effective Time multiplied by the Exchange Ratio at a proportionally adjusted conversion price (see Note 5c). In this respect, it was further agreed that the conversion of all or part of such Convertible Loans (including the issuance of future investment rights to the holders thereof upon such conversion (the “Future Investment Rights”) and the shares underlying such Future Investment Rights), whether before or after the Effective Time, shall not modify the Exchange Ratio.

 

The Merger will be accounted for as a reverse recapitalization which is outside the scope of ASC 805, “Business Combinations” (“ASC 805”), as OphthaliX, the legal acquirer, is considered a non-operating public shell, and is therefore not a business as defined in ASC 805. Under reverse capitalization accounting, the Company will be considered the acquirer for accounting and financial reporting purposes. The Merger will be accounted for in a manner that is substantially the same as a reverse acquisition under ASC 805, except that any excess fair value of the consideration transferred over the net fair value of the monetary assets of OphthaliX will be recognized as a reduction of equity.

  

  9  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 1:- GENERAL (Cont.)

 

  e. Risk factors

 

Wize is a clinical-stage biopharmaceutical company currently focused on the treatment of ophthalmic disorders, including DES. Wize has in-licensed certain rights to LO2A, a drug developed for the treatment of DES, and other ophthalmological illnesses, including CCH and Sjögren’s. Such license is subject to the payment of annual royalties as described in Note 4 to the annual consolidated financial statements of Wize as of December 31, 2016. Since April 2015, Wize has been financing its activity through numerous activities, including the issuance of ordinary shares and from loans from Ridge, Wize’s controlling shareholder, and from third parties. Wize has historically incurred net losses. As of September 30, 2017, Wize had an accumulated deficit of $25,547. Wize does not know whether or when it will become profitable. Following the Creditors Arrangement and to date, Wize has not commercialized any products or generated any revenues from product sales and accordingly it does not have a revenue stream to support its cost structure. Wize’s losses have resulted principally from costs incurred in development and discovery activities (including payments related to the License Agreement – see Note 4), along with costs related to its debt financing arrangements. Wize expects to continue to incur losses for the foreseeable future, and these losses will likely increase as it:

 

 

pays royalties related to the License Agreement;

 

initiates and manages pre-clinical development and clinical trials for LO2A;

 

seeks regulatory approvals for LO2A;

 

implements internal systems and infrastructures;

 

seeks to license additional technologies to develop;

 

hires management and other personnel; and

 

moves towards commercialization.

 

No certainty exists that Wize will be able to complete the development of LO2A for CCH, Sjögren’s or any other ophthalmic disorder, due to financial, technological or other difficulties. If LO2A fails in clinical trials or does not gain regulatory clearance or approval, or if LO2A does not achieve market acceptance, Wize may never become profitable. Even if Wize does achieve profitability, it may not be able to sustain or increase profitability on a quarterly or annual basis. Wize’s inability to achieve and then maintain profitability would negatively affect its business, financial condition, results of operations and cash flows. Moreover, Wize’s prospects must be considered in light of the risks and uncertainties encountered by an early-stage company and in highly regulated and competitive markets, such as the biopharmaceutical market, where regulatory approval and market acceptance of its products are uncertain. There can be no assurance that Wize’s efforts will ultimately be successful or result in revenues or profits.

 

  10  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 2:- SIGNIFICANT ACCOUNTING POLICIES

   

  a. The significant accounting policies applied in the annual consolidated financial statements of the Company as of December 31, 2016 are applied consistently in these unaudited interim consolidated financial statements.

 

  b. Principles of consolidation:

 

The consolidated financial statements include the accounts of the Company and its wholly owned subsidiary. Inter-company balances and transactions have been eliminated upon consolidation.

 

  c. Use of estimate in preparation of financial statements:

 

The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates, judgments and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. The Company evaluates on an ongoing basis its assumptions. The Company’s management believes that the estimates, judgments and assumptions used are reasonable based upon information available at the time they are made. These estimates, judgments and assumptions can affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the dates of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Actual results could differ from those estimates.

 

  d. Basic and diluted loss per share:

 

Basic loss per share is computed by dividing the loss for the period applicable to Ordinary Shareholders by the weighted average number of Ordinary Shares outstanding during the period.

 

In computing diluted loss per share, basic loss per share are adjusted to reflect the potential dilution that could occur upon the exercise of options or warrants issued or granted using the “treasury stock method” and upon the conversion of the Company’s 2016 loan and 2017 loan using the “if-converted method”, if the effect of each of such financial instruments is dilutive.

 

For the nine and three month periods ended September 30, 2017 and 2016, all outstanding stock options and other convertible instruments have been excluded from the calculation of the diluted net loss per share as all such securities are anti-dilutive for all years presented.

 

The total number of shares related to the outstanding options and warrants excluded from the calculation of diluted net loss per share were 8,296,358 and 4,170,643 for the nine months ended September 30, 2017 and 2016, respectively.

 

  11  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 3:- UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

The accompanying unaudited interim consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States for interim financial information. Accordingly, they do not include all the information and footnotes required by accounting principles generally accepted in the United States for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. Operating results for the three and nine month periods ended September 30, 2017 are not necessarily indicative of the results that may be expected for the year ending December 31, 2017 or for any other interim period. The accompanying interim consolidated financial statements and related notes should be read in conjunction with the audited consolidated financial statements and related notes for the year ended December 31, 2016. The accompanying consolidated balance sheet as of December 31, 2016, and the consolidated statements of comprehensive loss and changes in shareholders’ deficit for the year then ended have been derived from those audited financial statements.

  

NOTE 4:- LICENSE PURCHASE OBLIGATION

  

  a. As noted in Note 4 to the annual consolidated financial statements as of December 31, 2016, as consideration for the License Agreement, the Company undertook to pay a Minimal Commitment of licensing fees and royalties of no less than $500 in the first three years of the engagement. An amount of $100 was paid in May 2015, upon signing the License Agreement and amounts of $150 and $150 were paid in January 2016 and July 2017, respectively.

 

  b. The following table details the repayment dates of the remaining Minimal Commitment on the financial liability and the balance in the consolidated financial statements:

 

      As of December 31,
2016 (*)
   

As of

September 30, 2017 (*)

 
            Unaudited  
  Repayment dates:            
  January 1, 2017   $ 150     $ -  
  January 1, 2018     83       143  
                   
  Remaining balance     233       143  
                   
  Current liability     150       143  
  Non-current liability     83       -  
                   
  Total   $ 233     $ 143  

 

  (*) Upon initial recognition, the balance was discounted according to an annual discount rate of 21%, which in management’s opinion reflected the Company’s credit risk as of the initial recognition of the liability (see also Note 4 to the annual consolidated financial statements as of December 31, 2016).

 

  12  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 4:- LICENSE PURCHASE OBLIGATION (Cont.)

  

  c. In July 2017, the Company and Resdevco amended the License Agreement pursuant to which the annual royalties amount of $475 will be reduced to $150 (which includes also the unpaid amount of $100 under the Minimum Commitment) for 2018 and 2019. If the Company obtains an FDA marketing license during 2019, the Company is required to pay Resdevco the remainder of the payment of 2019. See also Note 4 to the annual consolidated financial statements as of December 31, 2016.

 

 

NOTE 5:- CONVERTIBLE LOANS AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT

 

  a. On March 20, 2016 (“Origination Date”), the Company entered into a convertible loan agreement (as amended on March 30, 2016, the “2016 Loan Agreement”) with Rimon Gold, whereby Rimon Gold extended a loan in the principal amount of up to NIS 2,000,000 (approximately $519 according to the exchange rate at the Origination Date), which bears interest at an annual rate of 4% (the “2016 Loan”). Pursuant to the 2016 Loan Agreement, as modified by the 2017 Loan Agreement (see also Note 5b), the 2016 Loan has a maturity date of December 31, 2017.

 

Under the 2016 Loan Agreement, Rimon Gold has the right, at its sole discretion, to convert any outstanding portion of the 2016 Loan, but not less than NIS 100,000 (approximately $26 according to the exchange rate at the Origination Date), into the Company’s ordinary shares at a fixed conversion price per share of NIS 0.6358 (approximately $0.16 according to the exchange rate at the Origination Date), subject to adjustments for stock splits and similar events set forth in the 2016 Loan Agreement.

 

In order to secure its obligations and performance pursuant to the 2016 Loan Agreement, the Company recorded a first priority fixed charge in favor of Rimon Gold on all of the Company’s rights, including its distribution rights, under the License Agreement, and a first priority floating charge on all of the Company’s rights, title and interest in all of its assets, as may exist from time to time (the agreements relating to such charges being referred to as the “Security Agreements”).

 

In light of the assignment of the License Agreement to the Subsidiary (as detailed in Note 4 to the annual consolidated financial statements as of December 31, 2016), in October 2016, the Subsidiary recorded identical liens to the aforementioned liens of the Company.

 

Rimon Gold is entitled, under certain circumstances, to demand repayment of the 2016 Loan, including among others: (i) if the Company breaches or fails to perform or is shown to have made a false statement, under the 2016 Loan Agreement or the Security Agreements; (ii) any failure of the Company to make a timely payment; (iii) upon the appointment of a receiver; (iv) the imposition of a lien on a material asset of the Company; (v) if the Company files a motion to stay proceedings; (vi) upon the expiration or termination of the License Agreement or if any party is in material breach of the License Agreement or if any party notifies the other of its intention to terminate the License Agreement; (vii) an adverse material change; or (viii) upon the non-performance of the Company pursuant to the 2017 Loan Agreement (see also Note 5b).

 

  13  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 5:- CONVERTIBLE LOAN AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT (Cont.)

  

The 2016 Loan Agreement and the Security Agreements contain a number of restrictive covenants that limit the Company’s operating flexibility. These covenants include, among other things, limitations on the creation of liens; on the incurrence of indebtedness; on dispositions of assets, mergers, acquisitions and other change of control transactions; on changes in the general nature of the Company’s business; restrictions on payments to related parties; restrictions on conducting rights offerings, and on the distribution of dividends.

 

In addition, under the 2016 Loan Agreement, as modified by the 2017 Loan Agreement (see also Note 5b), Rimon Gold has the detachable standalone right (not contingent on electing the loan conversion option), until the lapse of 18 months following the conversion of the loan granted by Rimon Gold under the 2016 Loan Agreement (“Right to Future Investment”), to invest up to NIS 3,000,000 (approximately $850 according to the exchange rate as of September 30, 2017), in the aggregate, at an exercise price per share that will reflect a 15% discount relative to the lowest price per share set for any Company offering, private or public, if the Company conducts any equity financing. Based on the original terms of the Right to Future Investment, management has determined that such right to acquire shares at a future date in the potentially variable investment amount, at a variable purchase price per share represents a derivative liability.

 

The Company used the services of an independent external appraiser to estimate the fair value of the derivative liability at the Origination Date and each reporting date. The fair value of such liability was measured upon initial recognition in an amount of NIS 423,000 (approximately $110 according to the exchange rate at the Origination Date). The fair value was based among other things on management’s estimates of 75% regarding the exercise probability of this right in a future offering and the forecast regarding the timing of a future offering as of that date.

 

The remaining amount of the 2016 Loan proceeds of NIS 1,577,000 (approximately $409 according to exchange rate at the Origination Date) (“Debt”) was allocated to the 2016 Loan. The Company applied ASC 470, “Debt with Conversion and Other Options” (“ASC 470”), pursuant to which the Company recognized and measured a Beneficial Conversion Feature (“BCF”) amounting to NIS 946,000 (approximately $246 according to the exchange rate at the commitment date) by allocating a portion of the proceeds equal to the intrinsic value of the conversion feature to additional paid-in-capital. The intrinsic value of the conversion feature was calculated on the Origination Date by using the effective conversion price to the 2016 Loan. The discount resulting from the BCF is amortized over the life of the 2016 Loan through financial expenses by using the effective interest method unless mandatorily converted earlier.

  

  14  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 5:- CONVERTIBLE LOAN AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT (Cont.)

  

The direct and incremental debt costs amounting to NIS 63,000 (approximately $16 according to the exchange rate at the Origination Date) were allocated to the Right to Future Investment and the 2016 Loan based on the same proportions as the proceeds allocation. The portion that was allocated to the Right to Future Investment amounting to $4 has been expensed immediately to finance expenses while the remaining amount of $12 was allocated and deducted from the 2016 Loan and is amortized over the life of the 2016 Loan through financial expenses by using the effective interest method unless mandatorily converted earlier.

 

For the nine month periods ended September 30, 2017 and 2016, the Company recorded finance expenses amounting to $166 and $75, respectively, due to the amortization of the discount that resulted from the BCF, the proceeds allocated to derivative liability and debt issuance costs. In addition, for the nine month periods ended September 30, 2017 and 2016, the Company recorded interest expense amounting to $17 and $10, respectively.

 

On February 22, 2017 (“Modification Date”), the expiration date of the Right of Future Investment that was associated with the 2016 Loan was extended from March 2018 to the end of the Option Period (see also Note 5b) and the exercise price was changed from a 15% discount of the lowest price per share set for the Company to a fixed price of NIS 0.85 per share. Accordingly, as of the Modification Date, the Right of Future Investment was no longer considered as a derivative liability. In addition, the difference between the fair value of the Right of Future Investment before and after the modification, which amounted to $246 was recognized as expenses within finance expenses, net for the nine month period ended September 30, 2017. In addition, the then outstanding amount related to the Right of Future Investment of $280 was reclassified from a derivative liability to equity upon the date of modification (see also Note 7).

 

  b. On January 15, 2017, the Company entered into a convertible loan agreement (the “2017 Loan Agreement”) with Ridge, and, by way of entering into assignments and assumption agreements following such date, also with Rimon Gold and Fisher (together, the “2017 Lenders”), whereby each of the 2017 lenders extended a loan in the principal amount of NIS 1,000,000 (approximately $283 according to the exchange rate as of September 30, 2017) and in the aggregate principal amount of NIS 3,000,000 (approximately $850 according to the exchange rate as of September 30, 2017), which bears interest at an annual rate of 4% (the “2017 Loan”). Pursuant to the 2017 Loan Agreement, the 2017 Loan has a maturity date of December 31, 2017.

  

  15  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 5:- CONVERTIBLE LOANS AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT (Cont.)

  

Under the 2017 Loan Agreement, each of the 2017 Lenders has the right, at its sole discretion, to convert any outstanding portion of the 2017 Loan, but no less than NIS 100,000 (approximately $28 according to exchange rate as of September 30, 2017), that the lender provided to the Company (each such portion converted, the “Converted Loan Amount”) into the Company’s ordinary shares at a conversion price per share equal to the lower of (i) NIS 1.00 (approximately $0.28 according to the exchange rate as of September 30, 2017) and (ii) the lowest price per share of the Company in any offering made by the Company following the date of the 2017 Loan Agreement and through the date of such requested conversion, subject to adjustments for stock splits and similar events set forth in the 2017 Loan Agreement (the “2017 Loan Conversion Price”). As a result of the 2017 PIPE (see also Note 9a), the current 2017 Loan Conversion Price for Rimon Gold, Fisher and Ridge was adjusted to NIS 0.70 (approximately $0.20 according to the exchange rate as of September 30, 2017).

 

In addition, upon exercise of the conversion right, the 2017 Loan Agreement grants the 2017 Lenders, for a period of 18 months following the conversion of the Converted Loan Amount, the right to make investments in the Company in an amount equal to NIS 1.50 for each NIS 1.00 of its respective Converted Loan Amount, at an agreed price per share equal to 120% of the then applicable 2017 Loan Conversion Price (the “Investment Option”). All shares that will be received by the 2017 Lenders upon the conversion of the 2017 Loan and upon the exercise of the Investment Option, will be unregistered shares. Such shares shall be restricted from sale for a period of 180 days from the date the Investment Option was exercised.

 

Ridge is entitled, under certain circumstances, to demand repayment of the 2017 Loan, including: (i) if the Company breaches or fails to perform or is shown to have made a false statement, under the 2017 Agreement or the Security Agreements; (ii) any failure of the Company to make a timely payment; (iii) upon the appointment of a receiver; (iv) the imposition of a lien on a material asset of the Company; (v) if the Company files a motion to freeze proceedings; or (vi) an adverse material change.

 

The 2017 Loan contains a number of restrictive covenants that limit the Company’s operating flexibility. These covenants include, among other things, limitations on the creation of liens; on the incurrence of indebtedness; on dispositions of assets, mergers, acquisitions and other change of control transactions; on changes in the general nature of the Company’s business; restrictions on payments to related parties; and on the distribution of dividends.

  

  16  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 5:- CONVERTIBLE LOANS AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT (Cont.)

 

As discussed in Note 6, prior to entering into the 2017 Loan Agreement, Ridge provided the following three loans to the Company, all of which bore interest at an annual rate equal to the interest rates of the Israeli government bonds: (i) NIS 250,000 was extended in November 2016, (ii) NIS 300,000 was extended in December 2016 and (iii) NIS 200,000 was extended in February 2017 (together, the “Ridge Interim Loans”). On March 30, 2017, after Ridge already provided NIS 250,000 under the 2017 Loan Agreement out of the NIS 1,000,000 committed by Ridge thereunder, Ridge exercised its right to have the Ridge Interim Loans being treated as a portion of the remaining loan commitment of NIS 1,000,000. As a result, the terms and conditions of the Ridge Interim Loans were modified to those included in the 2017 Loan Agreement.

 

As of the nine month period ended September 30, 2017, all the NIS 3,000,000 (including the above three loans amounting to NIS 750,000 and received from Ridge) has been funded.

 

In addition, as part of the 2017 Loan Agreement, the Company and the other lenders agreed that (i) the security interests made under the Security Agreements will also serve to secure the loans made by Rimon Gold under the 2017 Loan Agreement, and (ii) Rimon Gold will have the right to be repaid the full 2016 Loan prior to any repayment of the 2017 Loan.

 

The Company has considered the provisions of ASC 815-15, “Derivatives and Hedging – Embedded Derivatives” (“ASC 815-15”), and determined that the embedded conversion feature of the 2017 Loan cannot be considered as clearly and closely related to the host debt instrument, However, it was determined that the embedded conversion feature should not be separated from the host instrument because the embedded conversion option, if freestanding, does not meet the definition of a derivative in accordance with the provisions of ASC 815-10, since its terms do not require or permit net settlement. Thus, the conversion feature does not meet the characteristic of being readily convertible to cash.

 

The Company applied ASC 470-20, “Debt - Debt with Conversion and Other Options” which clarifies the accounting for instruments with BCF or contingently adjustable conversion ratios.

 

Pursuant to ASC 470-20-30, the amount of the BCF with respect to the 2017 Loan was calculated at the commitment date, as the difference between the conversion price (i.e. the entire proceeds received for the 2017 Loan) and the aggregate fair value of the common stock and other securities (which consist of the Investment Option) into which the 2017 Loan is convertible.

 

As such difference was determined to be greater than the amount of the entire proceeds received for the 2017 Loan, the amount of the discount assigned to the BCF was limited to the amount of the entire proceeds.

  

  17  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 5:- CONVERTIBLE LOANS AND FINANCIAL DERIVATIVE LIABILITY FOR THE RIGHT TO FUTURE INVESTMENT (Cont.)

 

Accordingly, the BCF amounting to NIS 3,000,000 (approximately $811 according to the average exchange rate at the commitment date) was recorded as a discount on the 2017 Loan with a corresponding amount credited directly to equity as additional paid-in capital. As a result, upon initial recognition, the amount related to the 2017 Loan was NIS 0. After the initial recognition, the discount on the 2017 Loan is amortized as interest expense over the term of the 2017 Loan.

 

In connection to the aforesaid 2017 Loan, the Company had direct and incremental debt issuance costs amounting to NIS 90,000 (approximately $26 according to the exchange rate as of September 30, 2017). Such costs were deferred and presented as an asset because the amount presented for 2017 loan was NIS 0. In subsequent periods, such expenses are amortized ratably over the term of the 2017 Loan. For the nine month period ended September 30, 2017, the Company recorded finance expense amounting to $17.

 

For the nine and three month periods ended September 30, 2017, the Company recorded finance expenses amounting $546 and $281, respectively ($186 and $93, respectively, out of which related to Ridge (see also Note 11)) due to the amortization of the discount that resulted from the BCF and the amortization of the debt issuance costs. In addition, for the nine month period ended September 30, 2017, the Company recorded interest expense amounting to $16 ($6 out of which related to Ridge (see also Note 11)).

 

  c.

In connection with the Merger and under the terms of the Merger Agreement, the “2016 Loan Agreement” and the "2017 Loan Agreement" became convertible into shares of Wize Pharma Inc. common stock which are equal to the number of Wize ordinary shares that were subject to a Convertible Loan immediately prior to the Effective Time multiplied by the Exchange Ratio at a proportionally adjusted conversion price.

  

NOTE 6:- LOANS FORM CONTROLLING SHAREHOLDER

 

  a. On November 15, 2016, the Company’s Board of Directors (after receiving the approval of the Audit Committee on November 14, 2016) approved the receipt of a short-term bridge loan in amount of NIS 250,000 (approximately $65 according to the exchange rate as of November 15, 2016) (“Loan”) from its controlling shareholder (“Shareholder”). The Loan was received on November 21, 2016. The Loan was not linked to any index, had no collateral and bears yearly interest at the level of the interest rate of Israel State Bonds (0.1% as of December 31, 2016). The Loan’s repayment date shall be by the end of the first quarter of 2017 but may be extended from time to time at the Shareholder’s discretion.

  

  18  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 6:- LOANS FORM CONTROLLING SHAREHOLDER (Cont.)

 

  b. On December 25, 2016, the Company’s Board of Directors (after receiving the approval of the Audit Committee on November 14, 2016) approved the receipt of an additional short-term bridge loan of NIS 300,000 (approximately $78 according to the exchange rate as of December 25, 2016) from the Shareholder under the same terms to those described above. An amount of NIS 200,000 (approximately $52 according to the exchange rate as of December 31, 2016) was received in December 2016 and the remaining amount of NIS 100,000 (approximately $26 according to the exchange rate as of December 31, 2016) was received during the three month period ended March 31, 2017. Accordingly, as of December 31, 2016, the total balance of the short-term bridge loans amounted to NIS 450,000 (approximately $117 according to exchange rate as of December 31, 2016).

 

  c. On February 19, 2017, the Company’s Board of Directors (after receiving the approval of the Audit Committee on February 16, 2017), approved the receipt of an additional short-term bridge loan of NIS 200,000 (approximately $54 according to the exchange rate as of February 19, 2017) from the Shareholder (the “Loan”). The Loan was not linked to any index, has no collateral and bears yearly interest at the level of the interest rate of Israel State Bonds. The loan’s repayment date shall be by the end of the first quarter of 2017 and will serve the Company in its current activity. The Shareholder may extend the loan’s redemption date from time to time at its discretion.

 

On March 30, 2017, the Company and the Shareholder agreed to convert the aforesaid bridge loans amounting to an aggregate amount of NIS 750,000 (approximately $206 according to the exchange rate as of March 31, 2017) into the 2017 Loan, the revised terms and conditions of which are described in Note 5b.

  

NOTE 7:- FAIR VALUE MEASUREMENT

 

ASC 820, “Fair Value Measurements and Disclosures” (“ASC 820”), defines fair value as the price that would be received to sell an asset or paid to transfer a liability (i.e., the “exit price”) in an orderly transaction between market participants at the measurement date.

 

In determining fair value, the Company uses various valuation approaches. ASC 820 establishes a hierarchy for inputs used in measuring fair value that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that the most observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing the asset or liability developed based on market data obtained from sources independent of the Company. Unobservable inputs are inputs that reflect the Company’s assumptions about the assumptions market participants would use in pricing the asset or liability developed based on the best information available in the circumstances.

  

  19  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 7:- FAIR VALUE MEASUREMENT (Cont.)

 

The hierarchy is broken down into three levels based on the inputs as follows:

 

  Level 1  - Valuations based on quoted prices in active markets for identical assets that the Company has the ability to access.
       
  Level 2  - Valuations based on one or more quoted prices in markets that are not active or for which all significant inputs are observable, either directly or indirectly.
       
  Level 3  - Valuations based on inputs that are unobservable and significant to the overall fair value measurement.

 

Following the modification described in Note 5a, based on the modified terms of the Right of Future Investment, the Company’s management engaged an external appraiser that measured the fair value of the Right of Future Investment immediately prior to the Modification Date at NIS 1,042,000 (approximately $280 according to the exchange rate as of the Modification Date) and reclassified such amount from a derivative liability to additional paid-in capital.

 

The following tabular presentation reflects the components of the derivative liability associated with such rights as of September 30, 2017 (unaudited):

 

      Fair value
of Right of Future Investment
 
         
  Balance at December 31, 2016   $ 34  
  Change in the fair value of derivative liability     246  
  Reclassification of derivative liability into equity     (280 )
           
  Balance at September 30, 2017 (unaudited)   $ -  

 

In addition, the Company’s financial instruments also include cash and cash equivalents, restricted bank deposit, other accounts receivable, trade payables and other accounts payables. As of September 30, 2017, the fair value of these financial instruments was not materially different from their carrying values due to the short-term maturities of such instruments.

 

NOTE 8:- COMMITMENTS AND CONTINGENCIES

  

Litigation

 

As further described in Note 10 in the annual consolidated financial statements as of December 31, 2016, from April 2015 to September 2015, the Company and its directors employed at the Company received a number of letters from Go D.M. Investments Ltd (“Go D.M.”), an Israeli public company, engaged in the field of repositioning of drugs, regarding its claims on various issues.

 

  20  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 8:- COMMITMENTS AND CONTINGENCIES (Cont.)

  

On October 5, 2016, the response was filed to the temporary injunction motion on behalf of the Company, claiming that the temporary injunction was baseless, both factually and legally, and that it was designed to serve as a tool for applying wrong and unfair pressure on its respondents, sabotage the Company’s business and threaten its officers and controlling shareholders. The Company claims that the injunction motion was filed with the sole purpose of preventing Mr. Noam Danenberg and Professor Halfon from exercising their right to vote at the General Meetings of Go D.M. shareholders and at the Go D.M. General Meeting that took place on September 26, 2016 and which had the appointment of the directors on its agenda in particular. The Company claimed that the stated motive for filing the motion leads to the necessary conclusion that the very fact that the motion was filed constitutes a cynical misuse of judicial proceedings. The Company also argued that the temporary injunction motion must be rejected, inter alia, due to the fact that the requested remedies are identical to the primary remedies claimed in the suits; due to the fact that some of them are ridiculous and draconic mandatory injunctions; due to the fact that the motion for a temporary injunction was filed with a significant delay, in spite of the fact that there is no urgency in resolving it and due to the fact that there is no evidentiary basis for the arguments made in it. In essence, the Company argued that Go D.M.’s claims against it, in the matter of the violation of the commitment to delineate activity, are wrong, and supported its response with two expert opinions.

 

Go D.M. asked for a stay of 7 days to reply to the response, and received the court’s approval. However, they subsequently asked for additional extensions, due to commencement of negotiations between Go D.M. and Mr. Danenberg and others, that may make the legal proceedings between them unnecessary, including the one to which the Company is a party.

 

On January 16, 2017, a settlement was signed between the Go D.M. and Mr. Dov Goldstein and D.D. Goldstein Assets and Investments Ltd. (through which Mr. Dov Goldstein holds Go D.M. shares) and between Panmed, Mr. Danenberg and Professor Halfon and the Company and Altshuler Shaham Trusts Ltd. (the settlement trustee) (the “Settlement”), the key points of which relevant to the Company are as follows:

 

  1. The parties and/or companies under their control undertook not to purchase each other’s shares (by themselves and/or through others), as well as sell the other party’s shares (inasmuch as they have any) in the period set in the Settlement, and not to act against the other party, its officers and controlling, shareholders, consultants, employees and service providers of any of the above in any manner, past, present and future.

 

  2. Within the framework of the Settlement, letters of waiver and release were signed by all of the parties as well as other related entities regarding the final, full and absolute waiver of any claims, suits and demands by the parties for legal proceedings and/or by anyone operating on their behalf (including subsidiaries, controlling shareholders and interested parties, executives and officers, directors and so on). Upon completing the preconditions set in the Settlement, an agreed-upon message will be submitted to the Court in each of the legal proceedings, according to which the parties seek to reject the relevant proceedings, with no order for expenses and a blocking order preventing the filing of any suit against the parties and/or anyone operating on their behalf.

 

  21  

 

  

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 8:- COMMITMENTS AND CONTINGENCIES (Cont.)

 

  3. Upon approving the Settlement and completing all of the actions detailed in the Settlement, none of the parties, their representatives and shareholders, as well as the Company and subsidiaries and related companies and/or anyone operating on their behalf and their shareholders shall have any claim, suit and demand from the other party, related parties and officer in it, past and present, in connection to any issue the grounds of which were before the signing of the Settlement by the certified Court.

 

  4. The Settlement established various provisions regarding the interim period, starting from the signing of the settlement agreement and until the completion of the pending terms.

 

  5. Completion of the Settlement is subject to the existence of various stipulations detailed in the Settlement and which are not under the Company’s control, within 90 days of signing (unless this date has been extended by the parties in writing), including the approval of the certified Court for certain actions to be carried out by Go D.M., and the commitment of the parties to the Settlement to vote in the gatherings of Go D.M. shareholders to approve the Settlement.

 

  6. Pursuant to the Settlement, additional agreements exist between some of the parties, some of which are Company controlling shareholders, but these agreements do not pertain to the Company.

 

On January 19, 2017, the Settlement was submitted to the Tel Aviv District Court for approval. On the same date, the Court ruled that the Settlement would be given the force of a legal ruling subject to meeting the preconditions as per the Settlement, including the Court’s approval of the arrangement in accordance with Section 350 of the Companies Law, 1999, and by February 21, 2017 the parties will update the Court on compliance with these conditions, and in the event that this takes place, the Settlement will be given the force of a legal ruling.

 

On February 16, 2017, Go D.M. filed a notice on the results of the Go D.M. shareholders meeting (Series 3) and a motion to approve an arrangement in accordance with Section 350(a) of the Companies Law and to the certain Go D.M related decision (hereinafter: “the Motion to Approve the Arrangement”), in which Go D.M., among other things, specified that the Settlement had been ratified by the meeting of Go D.M. shareholders and the meeting of Go D.M. option holders (Series 3) which took place on February 14, 2017, this with no objections.

 

On February 16, 2017, the Court ruled the motion to approve the arrangement shall be sent to the Securities Authority, Tel Aviv Stock Exchange and the Official Receiver for approval within 20 days.

 

On February 19, 2017, Go D.M. filed a motion asking that the respondents reply to the motion to approve the arrangements no later than February 26, 2017 and the case set for an internal memorandum on February 27, 2017. On the same date, the Court decided to alter the respondent’s response date so that these would respond to the motion to approve the arrangement by February 26, 2017. The Court also ruled that a hearing would take place on February 28, 2017.

  

  22  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 8:- COMMITMENTS AND CONTINGENCIES (Cont.)

  

On March 26, 2017, the parties entered into a settlement agreement pursuant to which it was agreed on final, full and absolute waiver of any claims, suits and demands by the parties for legal proceedings and/or by anyone operating on their behalf (including subsidiaries, controlling shareholders and interested parties, executives and officers, directors). As a result of this settlement agreement, the Company considers this matter closed.

 

NOTE 9:- SHAREHOLDERS’ DEFICIT

  

  a. Investment

 

On June 23, 2017, Wize entered into a Private Placement Agreement (the “2017 PIPE Agreements”) with each of Eliahu Peretz (“Peretz”), Yaacov Zrachia (“Zrachia”), Simcha Sadan (“Sadan”) and Jonathan Brian Rubini (“Rubini”, and together with Peretz, Zrachia and Sadan, the “2017 PIPE Investors”). Pursuant to the 2017 PIPE Agreements, the 2017 PIPE Investors agreed to invest a total of NIS 3,490,000 (approximately $986 according to exchange rate as of June 23, 2017) in exchange for a total of 4,985,714 ordinary shares of Wize (the “2017 PIPE”), at a price per share of NIS 0.70 (approximately $0.20 according to the exchange rate as of June 23, 2017), with Peretz undertaking to invest NIS 490,000 (approximately $139 according to the exchange rate as of June 23, 2017) in exchange for the private placement of 700,000 ordinary shares of Wize (the “Peretz Investment”) and each of Zrachia, Sadan and Rubini (the “Other Investors”) undertaking to invest NIS 1,000,000 (approximately $282 according to the exchange rate as of June 23, 2017) in exchange for the private placement of 1,428,571 ordinary shares of Wize each (together, the “Other Investments”).

 

Subject to the closing of the Merger (see also Note 1d), Wize also undertook to cause OphthaliX to grant warrants to each of the 2017 PIPE Investors (the “Warrants”), with each Warrant being exercisable into one share of common stock of OphthaliX, with a term of three years from the date of grant. According to the 2017 PIPE Agreements, the number of Warrants and the exercise price thereof will reflect, prior to giving effect to an adjustment based on the Exchange Ratio, (i) 735,000 warrants to Peretz and (ii) 1,500,000 warrants to each of the Other Investors, each warrant exercisable into one ordinary share of Wize, at an exercise price of NIS 0.29 per share (approximately $0.08 according to the exchange rate as of September 30, 2017). According to the Exchange Ratio, Peretz will be granted 3,046,266 Warrants exercisable into OphthaliX Common Stock and each of the Other Investors will be granted 6,216,869 Warrants exercisable into OphthaliX Common Stock. Sadan’s commitment to provide his portion of the Other Financing was conditioned upon Wize not raising more than NIS 3,500,000 (approximately $988 according to the exchange rate as of June 23, 2017) and not less than NIS 2,000,000 (approximately $565 according to the exchange rate as of June 23, 2017) in the 2017 PIPE, including the amount to be invested by Sadan.

  

  23  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 9:- SHAREHOLDERS’ DEFICIT (Cont.)

  

On June 22, 2017, Ridge provided notice to Wize that it has waived its right to adjust the 2017 Loan Conversion Price in connection with the Peretz Investment. In July 2017, Wize completed the Peretz Investment and Other Investments. However, Ridge did not waive its right to adjust the 2017 Loan Conversion Price in connection with the Other Investments.

 

As a result of the Peretz Investment and Other Investments, the current 2017 Loan Conversion Price for Rimon Gold, Fisher and Ridge was adjusted from NIS 1.00 (approximately $0.28 according to the exchange rate as of September 30, 2017) to NIS 0.70 (approximately $0.20 according to the exchange rate as of September 30, 2017).

 

During the nine month period ended September 30, 2017, the investment amount of NIS 3,490,000 from Peretz Investment and Other Investments has been received and the Company issued a total of 4,985,714 ordinary shares.

 

  b. Stock based-compensation:

 

As of August 20, 2015, the Company’s Board of Directors authorized through its 2015 Incentive Option Plan (the “2015 Plan”), the grant of options to officers, directors, advisors, management and other key employees. The Company reserved for grants of options up to 2,000,000 of the Company’s Ordinary Shares. The exercise price and the vesting schedule of the options granted will be subject to the Company’s Board of Directors discretion and expire 2 years after the ending of the vesting schedule on each batch. As of September 30, 2017, 975,000 options are available for future grants under 2015 Plan. Upon the Merger closing (see also Note 1d), all the outstanding options under 2015 Plan were cancelled.

 

A summary of the Company’s options activity for employees and director under the Company’s 2015 Plan is as follows:

  

     

Nine month period ended

September 30, 2017

 
      Number of options     Weighted average exercise price     Weighted average remaining contractual life  
                     
  Options outstanding at beginning of year     635,000     $ 0.64       2.16  
  Granted     -     $ -       -  
                           
  Options outstanding at end of period     635,000     $ 0.64       1.41  
                           
  Options vested and expected to be vested     635,000     $ 0.64       1.41  
                           
  Options exercisable at end of period     499,375     $ 0.74       1.13  

 

  24  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 9:- SHAREHOLDERS’ DEFICIT (Cont.)

  

As of September 30, 2017, the aggregate intrinsic value of outstanding and exercisable options is $117 and $88, respectively. The aggregate intrinsic value represents the total intrinsic value (the difference between the deemed fair value of the Company’s Ordinary Shares on the last day of third quarter of 2017 and the exercise price, multiplied by the number of in-the-money options) that would have been received by the option holders had all option holders exercised their options on September 30, 2017. This amount is impacted by the changes in the fair value of the Company’s shares.

 

  c. The Company granted options to certain non-employees under the Company’s 2015 Plan and accounted for these options in accordance with ASC 505-50.

 

The outstanding options granted to the Company’s non-employees are as follows:

 

  Grant date   Number of options    

Exercise

price

    Expiration date
  October 26, 2015     230,000     $ 1.03     February 1, 2018 - November 1, 2019
        230,000              

 

  d. The stock-based compensation expense amounting to $33, $21, $7 and $5 during the nine and three month periods ended September 30, 2017 and 2016 respectively was recognized as part of general and administrative expenses in the consolidated statements of comprehensive loss.

 

As of September 30, 2017, the total unrecognized estimated compensation cost related to non-vested stock options granted to employees, director and non-employees is $11, which is expected to be recognized over a weighted average period of approximately 0.78 years.

  

  25  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 10:- FINANCIAL EXPENSE, NET

  

     

Nine months ended

September 30,

   

Three months ended

September 30,

 
      2017     2016     2017     2016  
      Unaudited  
                           
  Accrued interest on convertible loans   $ 33       10       14       5  
  Amortization of BCF, proceeds allocated to the derivative liability and debt issuance costs for convertible loans     729       75       368       44  
  Amortization of discount resulting from exchange rate differences on license purchase obligation     1       22       5       6  
  Change in the fair value of derivative liability for Right to Future Investment     246       -       -       -  
  Bank commissions and others     7       1       5       (4 )
                                   
  Total financial expenses, net   $ 1,016     $ 108     $ 392     $ 51  

 

  *) Representing an amount less than $1

  

NOTE 11:- RELATED PARTIES BALANCES AND TRANSACTIONS

  

  a. Balances with interested and related parties:

 

      September 30,
    December 31,
 
      2017     2016  
      Unaudited        
               
  Included in other accounts payable (1)   $ 8     $ 13  
                   
  Loans from controlling shareholder (2)   $ -     $ 117  
                   
  Loan from controlling shareholder included  in Convertible Loans (2)   $ 283     $ -  
                   

 

  b. Transactions with interested and related parties:

 

     

Nine months ended

September 30,

   

Three months ended

September 30,

 
      2017     2016     2017     2016  
      Unaudited  
  Amounts charged to:                        
                           
  General and administrative expenses (1)   $ 61     $ 39     $ 20     $ 21  
                                   
  Finance expenses (2)   $ 192     $ -     $ 96     $ -  

 

  26  

 

 

WIZE PHARMA LTD. AND SUBSDIARY

 

NOTES TO UNAUDITED INTERIM CONSOLIDATED FINANCIAL STATEMENTS

 

U.S. dollars in thousands, except share and per share data

 

NOTE 11:- RELATED PARTIES BALANCES AND TRANSACTIONS (Cont.)

  

  (1) On September 30, 2015, the shareholders meeting approved the Employment Agreement (“Agreement”) of a relative to a controlling shareholder (“Relative”), as strategic consultant to the Company through a company under the Relative’s control, effective as of April 29, 2015, and for a period of three years from the date of such approval. The services will include strategic consulting in the field of business development in Israel and abroad, raising funds and others.

 

The consulting fees in accordance with the Agreement, shall be 25,000 NIS per month (approximately $7 according to the average exchange rate during the nine and three month periods ended September 30, 2017 and 2016) which may be updated by up to 30%, subject to the opinion of the Company’s Compensation Committee and the Company’s compliance with the goals set in the Agreement of the Relative.

 

  (2) See Note 5b and Note 6.

  

NOTE 12:- SUBSEQUENT EVENTS

  

  a.

The Company evaluates events or transactions that occur after the balance sheet date but prior to the issuance of the interim consolidated financial statements to identify matters that require additional disclosure. For its interim consolidated financial statements, as of September 30, 2017 and for the nine month period then ended, the Company evaluated subsequent events through November 21, 2017, the date that the interim consolidated financial statements were issued. Except as described below, the Company has concluded that no other subsequent events have occurred that require disclosure.

 

  b. As discussed in Note 1d, on October 16, 2017, the annual meeting of the Company’s shareholders approved the Merger, including the merger consideration and the delisting of the ordinary shares from the TASE.

 

  c. In addition, on October 31, 2017, the Israeli District Court approved the Arrangement as described in Note 1d.

 

  d.

On November 16, 2017, Wize completed its Merger with Merger Sub in accordance with the terms of the Merger Agreement pursuant to which Merger Sub merged with and into Wize, with Wize surviving as a wholly owned subsidiary of OphthaliX. The accompanying unaudited interim consolidated financial statements do not include any adjustments related to the Merger.

 

 

27

 

 

 

Exhibit 99.3

 

UNAUDITED PRO FORMA CONSOLIDATED FINANCIAL STATEMENTS

 

On May 21, 2017, Wize Pharma, Inc. (formerly, OphthaliX, Inc.), a Delaware corporation (“Company”), Wize Pharma Ltd., a company formed under the laws of the State of Israel (“Wize Israel”), and Bufiduck Ltd., a company formed under the laws of the State of Israel and a wholly owned subsidiary of the Company (“Merger Sub”), entered into an agreement and plan of merger (as amended on October 31, 2017, the “Merger Agreement”) that provided for, among other things, the merger of Merger Sub with and into Wize Israel, with Wize Israel continuing as the surviving entity and becoming a wholly owned subsidiary of the Company, on the terms and conditions set forth in the Merger Agreement (the “Merger”).

 

Upon closing of the Merger on November 16, 2017, holders of outstanding Wize Israel ordinary shares (collectively referred to herein as the Wize Israel shareholders) became entitled to receive 4.1445791236989 shares of the Company common stock per Wize Israel ordinary shares they held (the “Exchange Ratio”), or an aggregate of 93,971,259 shares of the Company common stock at closing. Immediately following the effective time of the Merger (the “Effective Time”), pre-merger Wize Israel shareholders owned approximately 90% of the outstanding common stock of the Company while pre-merger Company stockholders owned the remaining approximate 10%. At the Effective Time, pre-merger Company stockholders continued to own and hold their existing shares of the Company common stock.

 

The following unaudited pro forma consolidated financial statements give effect to the Merger. The Merger was structured as a reverse merger and Wize Israel was determined to be the accounting acquirer based upon the terms of the Merger and other factors including: (i) Wize Israel security holders owning approximately 90% of the Company immediately following the Effective Time, (ii) the entire board of directors of the Company post-Merger is filled by Wize Israel appointed directors, with the exception of Professor Michael Belkin who will remain a director of Wize US and (iii) Wize Israel’s management holding all key positions in the management of the Company post-Merger. The transaction will be accounted for under reverse capitalization accounting as a reverse acquisition under US GAAP, except that any excess fair value of the consideration transferred over the net fair value of the monetary assets of the Company will be recognized as a reduction of equity.

 

Pro Forma Information

 

The unaudited pro forma consolidated balance sheet as of September 30, 2017 and the unaudited pro forma consolidated statements of operations for the nine month period ended September 30, 2017 and the year ended December 31, 2016 are based on (i) the historical consolidated results of operations of Wize Israel and OcuWize Ltd., Wize Israel’s wholly owned Israeli subsidiary; (ii) and the historical consolidated results of operations of the Company and Eyefite Ltd., the Company’s former wholly owned Israeli s ubsidiary.

 

The unaudited pro forma consolidated balance sheet as of September 30, 2017 assumes that the Merger took place on September 30, 2017 and combines the historical balance sheets of the Company and Wize Israel as of September 30, 2017. The unaudited pro forma consolidated statements of operations for the nine month period ended September 30, 2017 and for the year ended December 31, 2016 assume that the Merger occurred on the first day of the periods presented, and combines the historical results of the Company and Wize Israel.

 

The unaudited pro forma consolidated financial statements are based on the assumptions and adjustments that are described in the accompanying notes. The unaudited pro forma consolidated financial statements and pro forma adjustments have been prepared based on preliminary estimates. Differences between these preliminary estimates and the final Merger will occur and these differences could have a material impact on the accompanying unaudited pro forma consolidated financial statements and the consolidated company’s future results of operations and financial position. The actual amounts recorded as of the completion of the Merger may differ materially from the information presented in these unaudited pro forma consolidated financial statements as a result of the amount, if any, of capital raised by Wize Israel between the signing of the Merger Agreement and closing of the Merger; the amount of cash used by the Company’s operations between the signing of the Merger Agreement and the closing of the Merger; the timing of the closing of the Merger; and other changes in the Wize Israel or the Company assets and liabilities that occur prior to the completion of the Merger.

 

The unaudited pro forma consolidated financial statements do not give effect to the potential impact of current financial conditions, regulatory matters, operating efficiencies or other savings or expenses that may be associated with the Merger. The unaudited pro forma consolidated financial statements have been prepared for illustrative purposes only and are not necessarily indicative of the financial position or results of operations in future periods or the results that actually would have been realized had the Company and Wize Israel been a consolidated company during the specified periods. The unaudited pro forma consolidated financial statements, including the notes thereto, should be read in conjunction with the audited consolidated financial statements of the Company and Wize Israel for the year ended December 31, 2016 and the unaudited interim consolidated financial statements of the Company and Wize Israel for the nine month period ended September 30, 2017.

 

 

 

 

Unaudited Pro Forma Consolidated Balance Sheet

(in thousands)

As of September 30, 2017

 

   

Historical

Wize Pharma Ltd.

   

Historical

OphthaliX,

Inc.

    Pro forma Merger Adjustments    

 

 

Note

   

 

Pro forma Consolidated

 
                               
ASSETS                              
                               
CURRENT ASSETS:                              
Cash and cash equivalents   $ 572     $ 11     $ (1 )   B     $ 582  
Restricted bank deposit     11       -       -             11  
Marketable securities     -       383       -             383  
Other accounts receivable     45       -       -             45  
                                       
Total current assets     628       394       (1 )           1,021  
                                       
NON-CURRENT ASSETS:                                      
                                       
Property and equipment, net     3       -       -             3  
                                       
Total non-current assets     3       -       -             3  
                                       
TOTAL ASSETS   $ 631     $ 394     $ (1 )         $ 1,024  
                                       
LIABILITIES AND STOCKOLDERS’ EQUITY (DEFICIT)                                      
                                       
CURRENT LIABILITIES:                                      
Related company   $ -     $ 4,942     $ (4,942 )   B, C     $ -  
Trade payables     44       -       -             44  
Other accounts payable     221       214       (80 )   B, C, E       355  
Current portion of license purchase obligation     143       -       -             143  
Convertible loans, net     1,082       -       -             1,082  
                                       
Total current liabilities     1,490       5,156       (5,022 )           1,624  
                                       
STOCKHOLDERS’ EQUITY (DEFICIT):                                      
Common stock     *)-       10       94     A       104  
Additional paid- in capital     25,481       5,519       579     A, C, D       31,579  
Treasury stock     (747 )     -       747     D       -  
Accumulated other comprehensive loss     (46 )     -       -             (46 )
Accumulated deficit     (25,547 )     (10,291 )     3,601     B       (32,237 )
                                       
Total stockholders’ equity (deficit)     (859 )     (4,762 )     5,021             (600 )
                                       
TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY (DEFICIT)   $ 631     $ 394     $ (1 )         $ 1,024  

  

*) Representing amount less than $1 thousand

 

  2  

 

 

Unaudited Pro Forma Consolidated Statements of Comprehensive Loss

For the Year Ended December 31, 2016

(in thousands, except share and per share data)

 

   

Historical

Wize Pharma Ltd.

   

Historical

OphthaliX,

Inc.

    Pro forma Merger Adjustments    

 

 

Note

   

 

Pro forma Consolidated

 
                               
Operating expenses:                              
Research and development expenses   $ 240     $ 199     $ (199 )   B     $ 240  
General and administrative expenses     794       432       (44 )   B       1,182  
                                       
Operating loss     1,034       631       (243 )           1,422  
                                       
Financial expense, net     105       285       (94 )   B       296  
                                       
Net loss   $ 1,139     $ 916     $ (337 )         $ 1,718  
                                       
Other comprehensive income:                                      
Foreign currency translation adjustments     3       -       -             3  
                                       
Comprehensive loss   $ 1,136     $ 916     $ (337 )         $ 1,715  
                                       
Net basic and diluted loss per share   $ 0.07     $ 0.09                   $ 0.02  
                                       
Weighted average number of Ordinary Shares used in computing basic and diluted net loss per share             10,441,251                     104,412,510  

 

Unaudited Pro Forma Consolidated Statements of Comprehensive Loss

For the Nine Month Period Ended September 30, 2017

(in thousands, except share and per share data)

 

   

Historical

Wize Pharma Ltd.

   

Historical

OphthaliX,

Inc.

    Pro forma Merger Adjustments    

 

 

Note

 

 

Pro forma Consolidated

 
                             
Operating expenses:                            
Research and development expenses   $ 288     $ 11     $ (11 )   B   $ 288  
General and administrative expenses     760       342       82     B, E     1,184  
                                     
Operating loss     1,048       353       71           1,472  
                                     
Financial expense, net     1,016       249       (73 )   B     1,192  
                                     
Net loss   $ 2,064     $ 602     $ (2 )       $ 2,664  
                                     
Other comprehensive loss:                                    
Foreign currency translation adjustments     51       -       -           51  
                                     
Comprehensive loss   $ 2,115     $ 602     $ (2 )       $ 2,715  
                                     
Net basic and diluted loss per share   $ 0.11     $ 0.06                 $ 0.02  
                                     
Weighted average number of Ordinary Shares used in computing basic and diluted net loss per share             10,441,251                   104,412,510  

 

  3  

 

 

Notes to the Unaudited Pro Forma Consolidated Financial Information

 

1. Description of the Acquisition and Basis of Presentation

 

On May 21, 2017, Wize Israel entered into the Merger Agreement with the Company, a company whose common stock is quoted on the OTC Pink. At the Effective Time of the Merger, Merger Sub merged with and into Wize Israel. Upon completion of the Merger, the separate corporate existence of Merger Sub ceased and Wize Israel continued as the surviving entity and as a wholly owned subsidiary of the Company. On November 16, 2017, the Company changed its name to “Wize Pharma, Inc.” The Company was a clinical-stage biopharmaceutical company focused on developing therapeutic products for the treatment of ophthalmic disorders. Prior to the Merger, the Company had no active business operations and was deemed to be a “shell company” as defined in Rule 12b-2 of the Exchange Act.

 

Subject to the terms and conditions of the Merger Agreement, at the Effective Time of the Merger, each ordinary share of Wize Israel that was issued and outstanding was automatically cancelled and converted into the right to receive that number of validly issued, fully paid and non-assessable shares of the Company common stock equal to the Exchange Ratio. Each convertible note or loan to purchase Wize Israel ordinary shares existing at the time of the Merger Agreement (the “Convertible Loans”) constitute a convertible note to purchase the number of shares of the Company common stock equal to the number of Wize Israel ordinary shares that were subject to a Convertible Loan immediately prior to the Effective Time multiplied by the Exchange Ratio at a proportionally adjusted conversion price. In this respect, it was further agreed that the conversion of all or part of such Convertible Loans (including future investment rights to the holders thereof upon such conversion (the “Future Investment Rights”) and the shares issuable upon exercise of the Future Investment Rights), whether before or after the Effective Time, shall not modify the Exchange Ratio.

 

The organizational history of Wize Israel is described in Wize Israel’s interim consolidated financial statements as of September 30, 2017.

 

2. Basis of Presentation

 

The unaudited pro forma consolidated financial statements were prepared in accordance with the regulations of the SEC. The unaudited pro forma consolidated balance sheet as of September 30, 2017 is presented as if the Merger had been completed on September 30, 2017. The unaudited pro forma consolidated statement of operations for the nine months period ended September 30, 2017 and the year ended December 31, 2016 assumes that the Merger occurs on the first day of the periods presented, and combines the historical results of the Company and Wize Israel.

 

Based on the terms of the Merger, Wize Israel is deemed to be the acquiring company for accounting purposes and the Merger will be accounted for under the reverse recapitalization accounting as a reverse acquisition. Under reverse recapitalization accounting, the assets and liabilities of the Company will be recorded, as of the completion of the Merger, at their historical amounts. Consequently, the interim consolidated financial statements of Wize Israel reflect the operations of the acquirer for accounting purposes together with a deemed issuance of shares, equivalent to the shares held by the former stockholders of the legal acquirer and a recapitalization of the equity of the accounting acquirer. These interim consolidated financial statements include the accounts of the Wize Israel since the effective date of the reverse recapitalization and the accounts of the Company since inception.

 

To the extent there are significant changes to the business following completion of the Merger, the assumptions and estimates set forth in the unaudited pro forma consolidated financial statements could change significantly. Accordingly, the pro forma adjustments are subject to further adjustments as additional information becomes available and as additional analyses are conducted following the completion of the Merger. There can be no assurances that these additional analyses will not result in material changes to the estimates of fair value.

 

  4  

 

 

3. Pro Forma Adjustments and Assumptions

 

The pro forma adjustments were based on the preliminary information available at the time of the preparation of the unaudited pro forma interim consolidated financial information. The unaudited pro forma interim consolidated financial information, including the notes thereto, are qualified in their entirety by reference to, and should be read in conjunction with, the historical interim consolidated financial information of Wize Israel and the Company as of September 30, 2017.

 

A. To reflect the conversion of all outstanding 22,673,295 ordinary shares of Wize Israel, no par value per share, into 93,971,259 shares of the Company’s common stock, par value $0.001 per share, according to the Exchange Ratio.

 

B. The consummation of the sale by the Company, prior to the Effective Time, on an “as-is” basis, of Eye-Fite to Can-Fite BioPharma Ltd. (“Can-Fite”), the Company’s former holder of approximately 82% of the outstanding shares of common stock of the Company, in exchange for the cancellation of all indebtedness owed by the Company and Eye-Fite to Can-Fite and the termination of the license agreement between the Company, to Can-Fite and Eye-Fite; all in accordance with the terms of the agreements attached to the Merger Agreement.

  

C. Representing liabilities amounting to $1,420,000 of the Company as of September 30, 2017, that will be waived by Can-Fite. Since the waiver is by Can-Fite such amount was recorded as part of additional paid in capital.

 

D. All shares of Wize Israel held immediately prior to the Effective Time by Wize Israel as treasury stock or otherwise, if any, and by the Company or any direct or indirect wholly owned subsidiary of the Company, was cancelled and no payment will be made with respect to those shares. Each issued and outstanding share of Merger Sub’s ordinary shares converted into one ordinary share of the post-merger Wize Israel, which will represent the only outstanding shares of capital stock of the post-merger Wize Israel from and after the Effective Time.

 

E. Due to the Merger, an amount of approximately $428,000 in expenses (of which $331,000 is outstanding as of September 30, 2017) is expected to be incurred by Wize Israel and the Company. Therefore, additional expenses amounting to $97,000 have been charged to general and administrative expenses during the period of nine months ended September 30, 2017.

 

 

5

 

Exhibit 99.4

 

Wize Pharma INC Date: November 2017 Investor Presentation All Rights Reserved

 

Forward - Looking Information This presentation contains forward - looking statements about our expectations, beliefs or intentions regarding, among other thing s, our product development efforts, business, financial condition, results of operations, strategies or prospects. In addition, from time to time, we or ou r representatives have made or may make forward - looking statements, orally or in writing. Forward - looking statements can be identified by the use of forward - lookin g words such as “believe,” “expect,” “intend,” “plan,” “may,” “should” or “anticipate” or their negatives or other variations of these words or other co mpa rable words or by the fact that these statements do not relate strictly to historical or current matters. These forward - looking statements may be included in, but are not limited to, this presentation, various filings made by us with the SEC, press releases or oral statements made by or with the approval of one of our authori zed executive officers. Forward - looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Beca use forward - looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause ou r a ctual results to differ materially from any future results expressed or implied by the forward - looking statements. Many factors could cause Wize’s actual activities or results to differ materially from the activities and results anticipated in forward - looking statements, including, but not limited to, the following: risks related to the substantial debt that we have incurred; our needs for additional fina nci ng; our dependence on a single compound, Lo2A and on the continuation of our license to commercialize LO2A; our inability to expand our rights under our lic ens e of LO2A; the initiation, timing, progress and results of our trials and product candidate development efforts; our ability to advance LO2A into clinical trial s o r to successfully complete our preclinical studies or clinical trials; our receipt of regulatory approvals for LO2A, and the timing of other regulatory fili ngs and approvals; the clinical development, commercialization and market acceptance of LO2A; our ability to establish and maintain corporate collaborations; the implemen tat ion of our business model and strategic plans for our business and product candidates; the scope of protection we are able to establish and maintain for in tel lectual property rights covering LO2A and our ability to operate our business without infringing the intellectual property rights of others; estimates of our exp enses, future revenues, and capital requirements; competitive companies, technologies and our industry; and statements as to the impact of the political and secu rit y situation in Israel on our business. More detailed information about the risks and uncertainties affecting Wize is contained under the heading “Risk Fac tor s” included in Wize’s Registration Statement on Form S - 4 filed with the SEC on September 5, 2017, and in other filings that Wize has made and may make with the SEC in the future. These statements are only current predictions and are subject to known and unknown risks, uncertainties and other factors tha t m ay cause our or our industry’s actual results, levels of activity, performance or achievements to be materially different from those anticipated by the forw ard - looking statements. Given these uncertainties, you should not rely upon forward - looking statements as predictions of future events. All forward - looking statements attributable to us or persons acting on our behalf included in, but not limited to, this presenta tion speak only as of the date hereof and are expressly qualified in their entirety by the foregoing. We undertake no obligations to update or revise forward - looking statements to reflect events or circumstances that arise after the date made or to reflect the occurrence of unanticipated events. In evaluating forward - looking statements, you should consider these risks and uncertainties. All Rights Reserved

 

Welcome to Wize Pharma Company Overview

 

WizePharma – At - A - Glance Ticker symbol: OTC (WIZP) Main shareholders: • Public: ~ 2 9 % • Ridge Valley Corp: ~20% • Private Investors: ~44% HQ: Israel Founded: 2015 Market Cap (last day of trading in TASE): NIS 46.0M (~$13.0M) as at 11 / 15 /17 Cash on hand: $572K as at 9/30/17 Manufacturing facilities: Pharma Stullen, Fareva All Rights Reserved

 

LO2A Opportunity Proven eye drops formulation Developed by the licensor, Prof. Disktein, For treatment of dry eye syndrome (DES), sold exclusively in Europe (*) with lubricant and anti irritant properties Ongoing clinical trials, results for pre - IND submission Phase II study to evaluate safety and efficacy of LO2A for patients with moderate to severe CCh and a Phase II trials to evaluate the Safety and Efficacy of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients with Sjögren’s syndrome, involving more than 100 patients (combined) Well established safety profile 1.25M packages sold 2016 (*) Significant business development opportunities In North America and China and other parts of the world and strategic partnerships Novel promising indications Treatment of patients suffering from DES and Conjunctivochalasis (CCh) as well as patient suffering from DES and Sjögern’s Syndrome Existing Manufacturing Facilities in France and Germany All Rights Reserved (*) Sales made by the licensor

 

LO2A Eye Drops Established sales history in Europe (*) Compatible Used with any contact lenses Anti - Irritant Anti - irritant properties Well - established safety profile No material side effects reported Preservative - Free Removes potential for irritation and sensitization which can damage the ocular surface and cornea Multi - dose Multi - dose form under development All Rights Reserved (*) Sales made by the licensor

 

Dry Eye Syndrome (DES) See Appendix • Several clinical trials in Europe involving more than 200 patients with Dry Eye • Documented beneficial effect of LO 2 A eye drops by both the investigators and the patient DES & Sjögren’s syndrome See Appendix • Investigator - initiated study • Performed in Hungary • 21 patients applied LO2A eye drops to both eyes in a single arm, open label trial for 3 months • The study demonstrated improvement in all parameters examined (with the exception of tear production) DES & CCh See Appendix • Investigator - initiated study was performed in Hungary (Article) • 20 patients with Grade 2 or 3 CCh, who had previously failed treatment on a variety of artificial tear preparations, applied LO2A in a single arm, open label study for 3 months • This study demonstrated that after 3 months, CCh severity decreased significantly Previous Clinical Trials All Rights Reserved

 

Competitive Landscape Market Overview

 

All Rights Reserved LO 2 A Eye Drops Wize has licensed certain rights to develop, purchase, market, sell and distribute LO2A for ophthalmic disorders in the United States, Israel, Ukraine and China. Wize has certain rights to add additional territories. Wize has the option to purchase licensor's agreements with its existing distributors in Switzerland, Germany and Holland.

 

European Sales Territory Manufactured in Distributor Packages sold in 2016 Hungary Pharma Stulln (Germany) PannonPharma 6,000 Germany Pharma Stulln (Germany) Pharma Stulln 70,000 The Netherlands Pharma Stulln (Germany) Tramedico 120,000 Switzerland Fareva (France) Thea Pharmaceuticals Ltd 980,000 Israel Pharma Stulln (Germany) Pharmidas Sales expected to commence 2018 Ukraine Pharma Stulln (Germany) EkoTechProm Premium Ltd. Sales expected to commence 2018 China Pharma Stulln (Germany) HPGC Sales expected to commence 2019 Future Sales Reseller Model Existing Royalties Model (*) All Rights Reserved (*) Existing sales by the licensor. Based on information provided by licensor.

 

+ + + Dry Eye Most common, instillation site irritation and decrease in visual acuity ( 5 - 25 % of patients). Blurred vision, eye irritation, conjunctival redness, pruritus (occur in 1 - 5 % of patients) 2 Most common, ocular burning ( 17 %). Conjunctival redness, tearing, blurred vision, eye pain, pruritus (occur in 1 - 5 % of patients) 1 Minor, transient ocular events expected with ophthalmic formulations, e.g ., blurred vision Safety $ 54 M (launched Aug 2016 ) 4 $ 1.5 B 3 ~$ 11 M (estimated) Sales in 2016 + + + Preservative free - - + Use with contact lenses - - + 5 Conjunctivalchalasis - - + 6 Sjögren ’ s Syndrome Competition Allergan Shire LO2A 1 https://www.allergan.com/assets/pdf/restasis_pi.pdf 2 https://www.shire.com/ - /media/shire/shireglobal/shirecom/pdffiles/media%20library/xiidra - clinical - development - program - infographi c.pdf 3 Allergan 2016 annual report (10K) 4 https://market - scope.com/breaking - post/shires - xiidra - dry - eye - treatment - earns - 54 - million - in - sales - in - 2016/ 5 approved in hungary 6 approved in The Netherlands All Rights Reserved

 

Prevalence of DES More than 16M adults in the US have dry eye syndrome 7 Approx. 19M prescriptions were filled in the US in 2013 for anti - inflammatory drugs administered by eye drops for ocular diseases and conditions, resulting in sales of approximately $2.2 billion (Source: IMS Health) Economic burden to US economy is $55.4B 8 7 http://www.sciencedirect.com/science/article/pii/S 0002939417302908 8 https://www.ncbi.nlm.nih.gov/pubmed/ 21045640 / All Rights Reserved

 

Prevalence of Sjögren’s Syndrome Affects about 0.2% - 4% of the adult population 9,10 Wide range, in part, reflects the lack of uniform diagnostic criteria Male/female ratio of 1:9 9 https://emedicine.medscape.com/article/332125 - overview#a6 10 https://www.ncbi.nlm.nih.gov/pubmed/20012976 A chronic autoimmune disorder characterized by exocrine gland dysfunction, affecting the salivary & lacrimal glands All Rights Reserved

 

Prevalence of CCh Refers to redundant folds of loose conjunctiva Increases dramatically with age 12 11 http://journals.plos.org/plosone/article?id= 10.1371 /journal.pone. 0132656 12 https://www.ncbi.nlm.nih.gov/pubmed/ 23036571 Present in up to a third of dry eye patients 11 (approx. 7 million people in the US) All Rights Reserved

 

Clinical Trials & Intellectual Property

 

Ongoing and Planned Clinical Trials DES & Sjogren’s syndrome (Phase II trial)* • Planned commencement: H1,2018 • Evaluate safety and efficacy of LO2A for Symptomatic Improvement of Dry Eye in Patients • with Sjögren’s Syndrome • Randomized, double - blind, placebo - controlled up to 40 patients • Study treatment with LO2A/placebo for 3 months • Designed in conjunction with previous trial designs historically performed for Sjogren syndrome DES & CCh (Phase II trial) • Evaluate safety and efficacy of LO2A for patients with moderate to severe CCh • Multi - center, randomized, double - blind, placebo - controlled up to • 62 patients • Designed according to US standards by Ora Clinic – a leading • US full - service ophthalmic CRO and product development firm • Subject to study protocol approval. All Rights Reserved

 

Timeline Q4/2017 Q1/2018 Q2/2018 Q3/2018 Q4/2018 Q 1 / 2019 Phase II Trial – DES Sjögren ’ s Syndrome (protocol approval) Start of DES Sjögren’s Syndrome Phase II Trial (1st patient) Phase II Trial CCh (completion) Phase II Trial DES Sjögren’s Syndrome (completion) Recruiting Key Option Leaders (KOL) Recruiting Advisory Board All Rights Reserved Pre - IND

 

Patents Territory Manufactured in Distributor International Patent Application Publ. No. WO2012150583 filed on April 5, 2012, assigned to Resdevco, Corresponding members include US Patent No. 8,912,166, Israeli Patent No. 212725, Japanese Patent No. 5957517 and pending European Pat. Appl. 2704747 Granted patents and patents to issue of this patent family will expire, without extension, in 2032 The use of LO2A for treating or alleviating CCh is protected by the patent family of, entitled EYE DROPS FOR TREATMENT OF CONJUNCTIVOCHALASIS. Provisional Patent Application No.62/467139, filed on March 5, 2017, assigned to Resdevco Patents to issue based on this provisional application will expire, without extension, in 2038. The use of LO2A for treating or alleviating irritation of the eye caused non - infectious diseases, such as Sjögren’s, is covered by, entitled EYE DROPS FOR TREATMENT OF IRRITATION NOT DUE TO INFECTION. US Patent No. 5,106,615 Expired The LO2A composition and use thereof fortreating or alleviating DES All Rights Reserved

 

Summary

 

• ~$13.5M market CAP as of 9/30/2017 (in TASE) • ~$5.3K daily average trading volume (H1/2017, in TASE) • Current Cash on hand: ~$450K • Additional Financial assets post Merger: ~$310K (*) • Monthly operating burn rate: ~$85K • ~104.4M shares outstanding • ~195M shares on a fully diluted basis • Average exercise price of convertible securities $ 0.06 (proceeds of ~$5M to the company) (*) As a result of the merger – additional ~$310K financial assets in OphthaliX. Financial Information FINANCING ROUNDS TO DATE $1.2M Private Placement $ 519 K Convertible Loan $ 827 K Convertible Loan $1M Private Placement 2017 2015 2016 2016 All Rights Reserved

 

LO 2 A Opportunity Proven eye drops formulation Developed by the licensor, Prof. Disktein, For treatment of dry eye syndrome (DES), sold exclusively in Europe (*) with lubricant and anti irritant properties Ongoing clinical trials, results for pre - IND submission Phase II study to evaluate safety and efficacy of LO2A for patients with moderate to severe CCh and a Phase II trials to evaluate the Safety and Efficacy of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients with Sjögren’s syndrome, involving more than 100 patients (combined) Well established safety profile 1.25M packages sold 2016 (*) Significant business development opportunities In North America and China and other parts of the world and strategic partnerships Novel promising indications Treatment of patients suffering from DES and Conjunctivochalasis (CCh) as well as patient suffering from DES and Sjögern’s Syndrome Existing Manufacturing Facilities in France and Germany All Rights Reserved (*) Sales made by the licensor.

 

Introducing. Management Team Or Eisenberg CFO, ACTING CEO Joined in March 2015 Formerly controller of Katzir Fund Group Formerly external controller/CFO of TASE co’s Accountant at Ernst & Young BA in Economics & Accounting (Haifa U.) CPA in Israel. OE Noam Danenberg COO Strategic advisor to Wize since April 2015 Served as a founder, director, investment advisor to a number of pharmaceutical and medical companies. Holds a MBA degree from Boston University ND Dr Adam Foley - Coper MEDICAL DIRECTOR Joined July 2015 Experience in development, regulatory strategy, clinical trial planning & execution, with leading international pharmaceutical companies MB Chb, University of Manchester Fellow of the Royal College of Surgeons M.Sc. from University College, London. AF All Rights Reserved

 

Introducing. Scientific Advisory Board Dr. Gideon Stein Medical Advisor More than 15 years experience in drug development, marketing and business development in the biotech industry in public and private companies. A graduate of the Faculty of Medicine at Tel Aviv University, with a specialization in Otolaryngology and Head & Neck Surgery. Holds a MBA and MHA from Tel Aviv University GS Prof Janos Nemeth Member of Scientific Advisory Board Ophthalmologic surgeon and Board Member of the Drug Discovery and Safety Center at Semmelweis University, Budapest, Hungary. Performed clinical trial with LO 2 A in the treatment of CCh JN Prof. Shabtay Dickstein Inventor and Scientific Advisor Professor of Pharmacology at the Hebrew U., Jerusalem. Between 1978 - 1998 head of the Unit of Cell Pharmacology at the Medical School of the Hebrew U., responsible for the development of several drugs currently marketed internationally. Recipient of Hebrew U’s Kaye Innovation Award (1996) and the Ferenc Papolczy Award of the Hungarian Society for Eye Research in (2005). Visiting professor at Stanford London and Oxford Universities. SD All Rights Reserved

 

Thanks 5 b Hanagar St. Hod Hasharon, Israel Tel: + 972 72 2600536 Cell: + 972 54 4318380 Fax: + 972 72 2600537 Visit wizepharma.com or email info@wizepharma.com

 

Appendix

 

Dry Eye – Clinical Trial Results (CCh) 1.9 2.4 2.6 2.8 0 1 week p= 0.19 p< 0.0001 Rose Bengal Score Eyecon Control "Rose Bengal Staining is the Clinical Gold Standard for the Diagnosis of Dry Eye" Dr. E.Knight , FDA, 1994 • Cellulose derivatives • PVP+hydroxyethylcellulose Improvement in Rose Bengal Score following 1 week of treatment ▪ 25 patients ▪ One eye randomized to treatment with LO 2 A and the other to the same preparation previously used by the patient (control) ▪ Patient satisfaction following 1 week of treatment with Conheal ® / Eyecon ® vs control Salomon, A. and Merin, S. The effect of new tear substitute containing glycerol and hyaluronate on keratoconjunctivitis sicca . J . Ocular Pharm. Therap. 14:497 - 502. 1998. All Rights Reserved

 

Clinical Results – Hungarian Study (CCh) Month 3* Comparison Month 3 vs Month 0 Comparison Month 3 vs Month 1 MeanlSD Shift parameter** and 95% Cl P value*** Shift parameter** and 95% Cl P value*** Right Left Right Left Right Left Right Left Right Left LIPCOF 1.4 1.4 - 2.0( - 2.0 - 1.0 ( - 2.0 <0.001 <0.001 0.0 ( - 1.0 0.0 (0.0 0.035 0.312 degree ± 0.6 ± 0.7 to - 1.0) to - 1.0) to 0.0) to 0.0) TFBUT 5.9 5.7 1.1 (0.2 0.9 (0.3 0.020 0.004 0.5( - 0.3 - 0.0 ( - 0.7 0.191 0.953 value ± 2.3 ± 1.8 to 2.0) to 1.5) to 1.3) to 0.6) Oxford 0.3 0.2 - 1.0( - 1.0 - 1.0 ( - 1.0 <0.001 <0.001 0.0( - 1.0 0.0 ( - 1.0 0.016 0.039 grade ± 0.4 ± 0.4 to - 1.0) to - 1.0) to 0.0) to 0.0) OSDI 15.6 ± 16.7 - 13.1 ( - 25.0 to - 8.3) <0.001 - 2.4( - 5.7 to 0.0) 0.012 Score LIPCOF = LId Parallel COnjunctival Folds (grading system for CCh severity) TFBUT = Tear film break - up time OSDI = Ocular Surface Disease Index (Patient questionnaire measuring subjective symtpom score All Rights Reserved

 

Clinical Results – Hungarian Study (CCh) 1 2 3 0 1 2 3 Conjunctivochalasis (LIPCOF degree) Time (months) Right eyes 0 1 2 3 0 1 2 3 Conjunctivochalasis (LIPCOF degree) Time (months) Left eyes 0 The graph demonstrates a statistically significant improvement in treating patients with CCh according to LIPCOF (LId Parallel COnjunctival Folds) Grade Figure 2: Degree of the conjunctivochalasis in terms of LIPCOF degrees after 1 and 3 months of artificial tear treatment. Artificial te ar treatment and measurement of LIPCOF degree on 20 patients were performed as described in Methods. The artificial tear investigated caused a significant decrease of LIPCOF deg ree on both eyes after one month of use that advanced further on the right eye (filled diamonds, solid line) significantly, and showed the same tendency on the left eye (open rect ang les, dashed line) after three months of use. Means and their standard errors of the LIPCOF degree are shown. Statistical evaluation was performed using the Wilcoxon Signed Rank Tes t. One and three asterisks note p<0.05 and p<0.001, respectively. All Rights Reserved

 

Clinical Results – Hungarian Study (CCh) Bar chart demonstrating the improvement in CCh per eye, measured by LIPCOF Grade, after one and three months treatment with Conheal® All Rights Reserved

 

Clinical Results – Hungarian Study (Sjögren ’ s) Figure 1: The artificial tears with high glycerine content ceased the corneal staining almost completely in the patients with Sjogren s ynd rome by the end of the three - month treatment. In the patients the initial ocular sin face staining was developed in spite of the earlier lasting use of ar tif icial tears. (Lisszamin - zöld festodés (Oxford skála szerint) = Lissamin green staining (according to the Oxford scale); Jobb szemek = Right ey es; Ido (honapok) = Duration (m onths), Bal szemek = left eyes) All Rights Reserved